ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
KMEHGPNO_00001 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KMEHGPNO_00002 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KMEHGPNO_00003 1.25e-51 yaaB - - S - - - Domain of unknown function (DUF370)
KMEHGPNO_00004 4.54e-264 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KMEHGPNO_00005 2.24e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
KMEHGPNO_00006 9.88e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KMEHGPNO_00007 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KMEHGPNO_00008 3.3e-70 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KMEHGPNO_00009 9.29e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KMEHGPNO_00010 1.83e-141 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
KMEHGPNO_00011 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KMEHGPNO_00012 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KMEHGPNO_00013 1.01e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
KMEHGPNO_00014 9e-193 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
KMEHGPNO_00015 9.26e-98 - - - S - - - Bacterial PH domain
KMEHGPNO_00016 4.79e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
KMEHGPNO_00017 5.62e-191 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
KMEHGPNO_00018 9.15e-145 yyaC - - S - - - Sporulation protein YyaC
KMEHGPNO_00019 5.34e-227 yyaD - - S - - - Membrane
KMEHGPNO_00020 7.41e-45 yyzM - - S - - - protein conserved in bacteria
KMEHGPNO_00021 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KMEHGPNO_00022 5.65e-256 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KMEHGPNO_00023 1.01e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
KMEHGPNO_00024 1.81e-103 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KMEHGPNO_00025 4.25e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KMEHGPNO_00026 9.83e-186 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
KMEHGPNO_00027 6.12e-230 ccpB - - K - - - Transcriptional regulator
KMEHGPNO_00028 2.07e-89 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KMEHGPNO_00029 3.26e-130 vatD 2.3.1.28, 2.3.1.79 - S ko:K00638,ko:K00661,ko:K18234 - br01600,ko00000,ko01000,ko01504 Bacterial transferase hexapeptide (six repeats)
KMEHGPNO_00030 0.0 - - - EGP ko:K08369 - ko00000,ko02000 Major facilitator superfamily
KMEHGPNO_00031 8.91e-217 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
KMEHGPNO_00032 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
KMEHGPNO_00034 1.99e-77 - - - - - - - -
KMEHGPNO_00035 3.93e-05 - - - L ko:K06400 - ko00000 Recombinase zinc beta ribbon domain
KMEHGPNO_00036 8.79e-17 - - - L - - - Recombinase
KMEHGPNO_00037 1.07e-06 - - - S - - - SIR2-like domain
KMEHGPNO_00038 4.41e-67 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
KMEHGPNO_00039 6.04e-83 - - - S ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Putative inner membrane exporter, YdcZ
KMEHGPNO_00040 3.64e-86 - - - S ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Putative inner membrane exporter, YdcZ
KMEHGPNO_00043 4.22e-120 yyaS - - S ko:K07149 - ko00000 Membrane
KMEHGPNO_00044 1.07e-92 yjcF - - S - - - Acetyltransferase (GNAT) domain
KMEHGPNO_00045 4.54e-100 yybA - - K - - - transcriptional
KMEHGPNO_00046 5.08e-163 - - - S - - - Metallo-beta-lactamase superfamily
KMEHGPNO_00047 2.39e-85 - - - S - - - SnoaL-like domain
KMEHGPNO_00048 2.39e-182 - - - - - - - -
KMEHGPNO_00049 1.25e-141 - - - K - - - TipAS antibiotic-recognition domain
KMEHGPNO_00050 1.01e-307 yybO - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
KMEHGPNO_00052 7.84e-91 - - - - - - - -
KMEHGPNO_00053 4.89e-210 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
KMEHGPNO_00054 6.68e-90 yybR - - K - - - Transcriptional regulator
KMEHGPNO_00055 2.89e-110 cotF - - M ko:K06329 - ko00000 Spore coat protein
KMEHGPNO_00057 5.23e-205 yybS - - S - - - membrane
KMEHGPNO_00058 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
KMEHGPNO_00059 2.74e-96 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
KMEHGPNO_00060 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KMEHGPNO_00061 5.96e-283 yycB - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
KMEHGPNO_00062 5.44e-22 yycC - - K - - - YycC-like protein
KMEHGPNO_00064 3.48e-40 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
KMEHGPNO_00065 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
KMEHGPNO_00066 9.45e-99 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KMEHGPNO_00067 1.29e-314 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KMEHGPNO_00072 1.45e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KMEHGPNO_00073 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KMEHGPNO_00074 0.0 yycH - - S - - - protein conserved in bacteria
KMEHGPNO_00075 6.94e-200 yycI - - S - - - protein conserved in bacteria
KMEHGPNO_00076 4.01e-191 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
KMEHGPNO_00077 9.43e-279 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KMEHGPNO_00078 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
KMEHGPNO_00079 1.23e-295 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
KMEHGPNO_00080 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
KMEHGPNO_00081 3.22e-213 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
KMEHGPNO_00083 7.14e-238 - - - S - - - aspartate phosphatase
KMEHGPNO_00084 3.55e-109 yycN - - K - - - Acetyltransferase
KMEHGPNO_00085 4.81e-169 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
KMEHGPNO_00086 1.94e-269 yycP - - - - - - -
KMEHGPNO_00087 1.69e-33 yycQ - - S - - - Protein of unknown function (DUF2651)
KMEHGPNO_00089 7.38e-297 yycR 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
KMEHGPNO_00090 4.34e-85 - - - - - - - -
KMEHGPNO_00092 5e-106 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KMEHGPNO_00093 2.94e-125 - - - - - - - -
KMEHGPNO_00094 4.53e-64 - - - - - - - -
KMEHGPNO_00095 5.82e-161 dcm 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 DNA (cytosine-5-)-methyltransferase activity
KMEHGPNO_00096 2.91e-168 - - - S - - - MvaI/BcnI restriction endonuclease family
KMEHGPNO_00098 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
KMEHGPNO_00099 8.12e-17 - - - - - - - -
KMEHGPNO_00100 1.35e-237 - - - S - - - Radical SAM superfamily
KMEHGPNO_00101 3.65e-172 - - - O ko:K16922 - ko00000,ko01002 Peptidase M50
KMEHGPNO_00102 3.42e-142 - - - P ko:K16917 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KMEHGPNO_00103 4.71e-153 - - - S ko:K16916 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
KMEHGPNO_00104 1.69e-23 - - - - - - - -
KMEHGPNO_00105 7.95e-159 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
KMEHGPNO_00106 4.38e-43 - 2.7.1.199 - G ko:K02777,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system
KMEHGPNO_00107 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KMEHGPNO_00108 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
KMEHGPNO_00109 9.33e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
KMEHGPNO_00110 0.0 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KMEHGPNO_00111 2.05e-295 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
KMEHGPNO_00112 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
KMEHGPNO_00113 4.42e-164 gntR - - K ko:K11476 - ko00000,ko03000 transcriptional
KMEHGPNO_00114 1.11e-261 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
KMEHGPNO_00115 3.62e-245 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
KMEHGPNO_00116 2.19e-153 yxaC - - M - - - effector of murein hydrolase
KMEHGPNO_00117 2.08e-77 - - - S ko:K06518 - ko00000,ko02000 LrgA family
KMEHGPNO_00118 6.83e-94 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
KMEHGPNO_00119 6.1e-255 yxnA - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
KMEHGPNO_00120 3.22e-129 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
KMEHGPNO_00121 8.59e-250 - 1.13.11.24 - S ko:K07155 - ko00000,ko01000 AraC-like ligand binding domain
KMEHGPNO_00122 2.53e-284 - - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
KMEHGPNO_00123 4.03e-99 yxaI - - S - - - membrane protein domain
KMEHGPNO_00124 3.11e-80 - - - S - - - Family of unknown function (DUF5391)
KMEHGPNO_00125 2.63e-137 yxaL - - S - - - PQQ-like domain
KMEHGPNO_00126 4.03e-42 yxaI - - S - - - membrane protein domain
KMEHGPNO_00127 9.79e-313 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
KMEHGPNO_00128 2e-263 yxbF - - K - - - Bacterial regulatory proteins, tetR family
KMEHGPNO_00129 1.33e-189 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
KMEHGPNO_00131 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
KMEHGPNO_00132 1.69e-312 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
KMEHGPNO_00133 2.13e-64 yxcD - - S - - - Protein of unknown function (DUF2653)
KMEHGPNO_00135 1.74e-224 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
KMEHGPNO_00136 1.56e-177 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
KMEHGPNO_00137 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KMEHGPNO_00138 1.41e-199 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
KMEHGPNO_00139 1.75e-227 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
KMEHGPNO_00140 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
KMEHGPNO_00141 7.09e-222 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
KMEHGPNO_00142 4.89e-297 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
KMEHGPNO_00143 1.55e-251 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
KMEHGPNO_00144 1.08e-212 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
KMEHGPNO_00145 5.63e-194 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
KMEHGPNO_00146 2.83e-204 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
KMEHGPNO_00147 2.8e-160 yxdJ - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KMEHGPNO_00148 3.15e-230 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KMEHGPNO_00149 4.46e-180 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
KMEHGPNO_00150 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
KMEHGPNO_00151 5.95e-77 yxeA - - S - - - Protein of unknown function (DUF1093)
KMEHGPNO_00152 3.51e-225 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KMEHGPNO_00153 9.65e-91 - - - - - - - -
KMEHGPNO_00154 7.57e-28 yxeD - - - - - - -
KMEHGPNO_00155 7.32e-42 yxeE - - - - - - -
KMEHGPNO_00158 2.71e-192 yxeH - - S - - - hydrolases of the HAD superfamily
KMEHGPNO_00159 2.68e-207 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
KMEHGPNO_00160 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KMEHGPNO_00161 1.54e-121 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KMEHGPNO_00162 4.3e-186 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
KMEHGPNO_00163 3e-148 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
KMEHGPNO_00164 1.67e-171 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KMEHGPNO_00165 3.93e-270 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
KMEHGPNO_00166 1.21e-315 yxeQ - - S - - - MmgE/PrpD family
KMEHGPNO_00167 4.46e-255 eutH - - E ko:K04023 - ko00000 Ethanolamine utilisation protein, EutH
KMEHGPNO_00168 5.06e-195 - - - S - - - Domain of Unknown Function (DUF1206)
KMEHGPNO_00169 1.22e-221 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
KMEHGPNO_00170 1.18e-149 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KMEHGPNO_00171 1.92e-263 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KMEHGPNO_00172 9.46e-298 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
KMEHGPNO_00173 0.0 ybgF - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
KMEHGPNO_00174 3.98e-230 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
KMEHGPNO_00175 4.32e-297 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
KMEHGPNO_00176 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KMEHGPNO_00177 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
KMEHGPNO_00178 7.02e-103 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
KMEHGPNO_00179 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
KMEHGPNO_00180 5.89e-34 - - - S - - - Domain of unknown function (DUF5082)
KMEHGPNO_00181 1.33e-52 yxiC - - S - - - Family of unknown function (DUF5344)
KMEHGPNO_00182 8.32e-172 - - - S ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
KMEHGPNO_00183 9.21e-44 - - - - - - - -
KMEHGPNO_00184 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KMEHGPNO_00185 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KMEHGPNO_00186 6.99e-94 yxiE - - T - - - Belongs to the universal stress protein A family
KMEHGPNO_00187 2.07e-210 yxxF - - EG - - - EamA-like transporter family
KMEHGPNO_00188 0.0 wapA - - M - - - COG3209 Rhs family protein
KMEHGPNO_00191 5.65e-80 - - - S - - - Protein of unknown function (DUF2812)
KMEHGPNO_00192 2.01e-69 - - - K - - - Transcriptional regulator PadR-like family
KMEHGPNO_00193 1.18e-272 - - - E - - - GDSL-like Lipase/Acylhydrolase
KMEHGPNO_00194 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
KMEHGPNO_00195 2.56e-290 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
KMEHGPNO_00196 3.07e-142 - - - - - - - -
KMEHGPNO_00197 5.66e-193 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
KMEHGPNO_00198 1.77e-183 bglS - - M - - - licheninase activity
KMEHGPNO_00199 2e-284 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
KMEHGPNO_00200 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
KMEHGPNO_00201 2.28e-63 yxiS - - - - - - -
KMEHGPNO_00202 1.71e-132 - - - T - - - Domain of unknown function (DUF4163)
KMEHGPNO_00203 1.72e-268 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KMEHGPNO_00204 5.47e-198 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
KMEHGPNO_00205 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
KMEHGPNO_00206 2.21e-166 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KMEHGPNO_00207 5.91e-151 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
KMEHGPNO_00208 2.77e-174 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
KMEHGPNO_00209 1.28e-274 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
KMEHGPNO_00210 8.66e-277 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
KMEHGPNO_00211 4.98e-112 yxjI - - S - - - LURP-one-related
KMEHGPNO_00213 3.16e-298 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
KMEHGPNO_00214 1.05e-145 - - - K ko:K02479 - ko00000,ko02022 helix_turn_helix, Lux Regulon
KMEHGPNO_00215 6.98e-243 - - - T - - - Signal transduction histidine kinase
KMEHGPNO_00216 3.81e-100 - - - S - - - Protein of unknown function (DUF1453)
KMEHGPNO_00217 8.17e-209 - - - K - - - LysR substrate binding domain
KMEHGPNO_00218 3.9e-121 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
KMEHGPNO_00219 1.05e-249 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
KMEHGPNO_00220 7.81e-182 - - - - - - - -
KMEHGPNO_00221 2.29e-188 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
KMEHGPNO_00222 0.0 aldY 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KMEHGPNO_00223 1.93e-210 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
KMEHGPNO_00224 3.44e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KMEHGPNO_00225 7.49e-199 yxkH - - G - - - Polysaccharide deacetylase
KMEHGPNO_00227 0.0 - - - O - - - Peptidase family M48
KMEHGPNO_00228 2.67e-308 cimH - - C - - - COG3493 Na citrate symporter
KMEHGPNO_00229 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
KMEHGPNO_00230 1.36e-242 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
KMEHGPNO_00231 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
KMEHGPNO_00232 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
KMEHGPNO_00233 8.79e-201 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KMEHGPNO_00234 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
KMEHGPNO_00235 2.6e-124 sigY - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
KMEHGPNO_00236 2.74e-62 yxlC - - S - - - Family of unknown function (DUF5345)
KMEHGPNO_00237 1.63e-39 - - - - - - - -
KMEHGPNO_00238 2.17e-39 yxlE - - S - - - Phospholipase_D-nuclease N-terminal
KMEHGPNO_00239 2.09e-213 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KMEHGPNO_00240 1.61e-178 yxlG - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
KMEHGPNO_00241 4.11e-273 yxlH - - EGP - - - Major Facilitator Superfamily
KMEHGPNO_00242 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
KMEHGPNO_00243 3.23e-145 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
KMEHGPNO_00244 8.94e-28 yxzF - - - - - - -
KMEHGPNO_00245 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
KMEHGPNO_00246 1.89e-67 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
KMEHGPNO_00247 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KMEHGPNO_00248 3.2e-50 licA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KMEHGPNO_00249 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
KMEHGPNO_00250 1.07e-263 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
KMEHGPNO_00251 2.91e-178 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
KMEHGPNO_00252 4.09e-294 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KMEHGPNO_00253 6.83e-50 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KMEHGPNO_00254 2.68e-296 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
KMEHGPNO_00255 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KMEHGPNO_00256 5.1e-213 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
KMEHGPNO_00257 2.52e-149 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
KMEHGPNO_00258 2.74e-315 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
KMEHGPNO_00259 4.48e-297 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KMEHGPNO_00260 3.57e-114 ywaE - - K - - - Transcriptional regulator
KMEHGPNO_00261 7.88e-155 ywaF - - S - - - Integral membrane protein
KMEHGPNO_00262 3.78e-216 gspA - - M - - - General stress
KMEHGPNO_00263 2.6e-195 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
KMEHGPNO_00264 2.4e-311 sacX 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KMEHGPNO_00265 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
KMEHGPNO_00266 4.49e-313 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KMEHGPNO_00267 4.65e-157 ywbB - - S - - - Protein of unknown function (DUF2711)
KMEHGPNO_00268 1.99e-87 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
KMEHGPNO_00269 4.17e-280 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
KMEHGPNO_00270 3.13e-38 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
KMEHGPNO_00271 1.51e-279 ywbF - - EGP ko:K05820 - ko00000,ko02000 Nucleoside H+ symporter
KMEHGPNO_00272 1.21e-143 ywbG - - M - - - effector of murein hydrolase
KMEHGPNO_00273 1.1e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
KMEHGPNO_00274 2.7e-203 ywbI - - K - - - Transcriptional regulator
KMEHGPNO_00275 3.25e-185 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KMEHGPNO_00276 2.88e-145 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
KMEHGPNO_00277 0.0 - - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
KMEHGPNO_00278 5.94e-247 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
KMEHGPNO_00279 1.72e-305 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
KMEHGPNO_00280 5.38e-143 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
KMEHGPNO_00281 0.0 ywcA - - S ko:K14393 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KMEHGPNO_00282 6.1e-64 ywcB - - S - - - Protein of unknown function, DUF485
KMEHGPNO_00284 3.99e-157 ywcC - - K - - - transcriptional regulator
KMEHGPNO_00285 3.33e-77 gtcA - - S - - - GtrA-like protein
KMEHGPNO_00286 3.6e-287 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KMEHGPNO_00287 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
KMEHGPNO_00288 5.11e-49 ydaS - - S - - - membrane
KMEHGPNO_00289 6.94e-226 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
KMEHGPNO_00290 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KMEHGPNO_00291 1.2e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
KMEHGPNO_00292 1.12e-83 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
KMEHGPNO_00293 6.61e-52 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
KMEHGPNO_00294 8.89e-269 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
KMEHGPNO_00295 2.31e-178 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
KMEHGPNO_00296 4.19e-239 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KMEHGPNO_00297 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
KMEHGPNO_00299 1.29e-193 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
KMEHGPNO_00300 6.85e-179 - - - P ko:K02598 - ko00000,ko02000 Formate/nitrite transporter
KMEHGPNO_00301 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KMEHGPNO_00302 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
KMEHGPNO_00303 6.19e-39 ywdA - - - - - - -
KMEHGPNO_00304 2.21e-187 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
KMEHGPNO_00305 7.92e-76 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
KMEHGPNO_00306 8.74e-146 ywdD - - - - - - -
KMEHGPNO_00308 4.68e-192 ywdF - - S - - - Glycosyltransferase like family 2
KMEHGPNO_00309 2.71e-165 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KMEHGPNO_00310 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
KMEHGPNO_00311 2.18e-63 ywdI - - S - - - Family of unknown function (DUF5327)
KMEHGPNO_00312 5.33e-303 ywdJ - - F - - - Xanthine uracil
KMEHGPNO_00313 1.59e-78 ywdK - - S - - - small membrane protein
KMEHGPNO_00314 3.62e-112 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
KMEHGPNO_00315 4.68e-186 spsA - - M - - - Spore Coat
KMEHGPNO_00316 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
KMEHGPNO_00317 6.44e-285 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
KMEHGPNO_00318 1.04e-210 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
KMEHGPNO_00319 6.8e-272 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
KMEHGPNO_00320 5.2e-166 spsF - - M ko:K07257 - ko00000 Spore Coat
KMEHGPNO_00321 5.98e-242 spsG - - M - - - Spore Coat
KMEHGPNO_00322 6.13e-177 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KMEHGPNO_00323 1.51e-232 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KMEHGPNO_00324 5.74e-205 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KMEHGPNO_00325 3.07e-112 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
KMEHGPNO_00326 6.13e-100 - - - - - - - -
KMEHGPNO_00327 5.19e-311 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
KMEHGPNO_00328 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
KMEHGPNO_00329 0.0 rocB - - E - - - arginine degradation protein
KMEHGPNO_00330 3.01e-315 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
KMEHGPNO_00331 8.95e-274 ywfA - - EGP - - - -transporter
KMEHGPNO_00332 5.11e-146 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
KMEHGPNO_00333 1.24e-175 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
KMEHGPNO_00334 3.83e-179 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KMEHGPNO_00335 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
KMEHGPNO_00336 7.22e-264 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
KMEHGPNO_00337 2.47e-294 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
KMEHGPNO_00338 7.94e-175 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
KMEHGPNO_00339 3.43e-187 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
KMEHGPNO_00340 1.67e-224 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
KMEHGPNO_00341 2.16e-208 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
KMEHGPNO_00342 1.24e-198 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
KMEHGPNO_00343 2.14e-202 ywfM - - EG ko:K03298 - ko00000,ko02000 EamA-like transporter family
KMEHGPNO_00344 6.58e-146 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
KMEHGPNO_00345 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
KMEHGPNO_00346 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
KMEHGPNO_00347 1.47e-115 ywgA - - - ko:K09388 - ko00000 -
KMEHGPNO_00348 1.28e-102 yffB - - K - - - Transcriptional regulator
KMEHGPNO_00349 1.15e-301 mmr - - U ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
KMEHGPNO_00351 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KMEHGPNO_00352 7.19e-94 ywhA - - K - - - Transcriptional regulator
KMEHGPNO_00353 1.43e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
KMEHGPNO_00354 3.29e-154 ywhC - - S - - - Peptidase family M50
KMEHGPNO_00355 1.92e-123 ywhD - - S - - - YwhD family
KMEHGPNO_00356 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
KMEHGPNO_00357 1.93e-204 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KMEHGPNO_00358 6.02e-215 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
KMEHGPNO_00360 1.4e-74 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
KMEHGPNO_00363 1.3e-10 - - - - - - - -
KMEHGPNO_00366 8.17e-100 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
KMEHGPNO_00367 9.47e-275 ywhK - - CO - - - amine dehydrogenase activity
KMEHGPNO_00368 9.89e-315 ywhL - - CO - - - amine dehydrogenase activity
KMEHGPNO_00370 5.85e-316 - - - L - - - Peptidase, M16
KMEHGPNO_00371 1.2e-276 - 2.7.1.26, 2.7.7.2 - L ko:K07263,ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase, M16
KMEHGPNO_00372 1.39e-296 mgtA 3.6.3.2 - P ko:K01531,ko:K16905 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPase, P-type transporting, HAD superfamily, subfamily IC
KMEHGPNO_00373 1.5e-169 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
KMEHGPNO_00375 0.0 - - - C ko:K22227 - ko00000 Fe-S oxidoreductases
KMEHGPNO_00376 3.71e-12 - - - S - - - Bacteriocin subtilosin A
KMEHGPNO_00377 4.64e-96 ywiB - - S - - - protein conserved in bacteria
KMEHGPNO_00378 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
KMEHGPNO_00379 1.2e-273 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
KMEHGPNO_00380 3.27e-168 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
KMEHGPNO_00381 9.09e-154 ywiC - - S - - - YwiC-like protein
KMEHGPNO_00382 1.49e-11 ywiC - - S - - - YwiC-like protein
KMEHGPNO_00383 9.74e-108 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
KMEHGPNO_00384 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KMEHGPNO_00385 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
KMEHGPNO_00386 9.27e-121 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
KMEHGPNO_00387 1.02e-159 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
KMEHGPNO_00388 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KMEHGPNO_00389 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
KMEHGPNO_00390 5.49e-124 ywjB - - H - - - RibD C-terminal domain
KMEHGPNO_00391 1.32e-57 ywjC - - - - - - -
KMEHGPNO_00392 2.82e-235 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
KMEHGPNO_00393 1.59e-285 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
KMEHGPNO_00394 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
KMEHGPNO_00395 2.98e-269 acdA - - I - - - acyl-CoA dehydrogenase
KMEHGPNO_00396 1.03e-82 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KMEHGPNO_00397 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KMEHGPNO_00398 2.24e-118 ywjG - - S - - - Domain of unknown function (DUF2529)
KMEHGPNO_00399 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
KMEHGPNO_00400 7.82e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
KMEHGPNO_00401 5.69e-147 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KMEHGPNO_00402 2.26e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KMEHGPNO_00403 2.03e-224 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
KMEHGPNO_00404 5.53e-303 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KMEHGPNO_00405 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
KMEHGPNO_00406 9.96e-135 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
KMEHGPNO_00407 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
KMEHGPNO_00408 3.24e-204 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
KMEHGPNO_00409 9.96e-116 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
KMEHGPNO_00410 1.19e-89 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KMEHGPNO_00411 9.95e-245 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KMEHGPNO_00412 8.46e-205 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KMEHGPNO_00414 5.61e-73 ywlA - - S - - - Uncharacterised protein family (UPF0715)
KMEHGPNO_00415 9.35e-152 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
KMEHGPNO_00416 1.79e-100 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
KMEHGPNO_00417 7.37e-251 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KMEHGPNO_00418 4.56e-117 mntP - - P - - - Probably functions as a manganese efflux pump
KMEHGPNO_00419 1.58e-100 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KMEHGPNO_00420 2.35e-106 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
KMEHGPNO_00421 2.49e-123 ywlG - - S - - - Belongs to the UPF0340 family
KMEHGPNO_00422 1.25e-302 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KMEHGPNO_00423 5.5e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KMEHGPNO_00424 1.91e-81 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
KMEHGPNO_00425 6.06e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
KMEHGPNO_00426 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KMEHGPNO_00427 2.62e-79 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KMEHGPNO_00428 7.94e-116 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KMEHGPNO_00429 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KMEHGPNO_00430 2.58e-194 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KMEHGPNO_00431 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KMEHGPNO_00432 3.89e-72 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
KMEHGPNO_00433 7.16e-114 ywmA - - - - - - -
KMEHGPNO_00434 4.54e-45 ywzB - - S - - - membrane
KMEHGPNO_00435 1.97e-173 ywmB - - S - - - TATA-box binding
KMEHGPNO_00436 4.96e-306 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KMEHGPNO_00437 2.8e-233 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
KMEHGPNO_00438 1.89e-157 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
KMEHGPNO_00439 1.02e-155 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
KMEHGPNO_00441 2.22e-187 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KMEHGPNO_00442 1.47e-243 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KMEHGPNO_00443 3.1e-129 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
KMEHGPNO_00444 1.21e-109 ywmF - - S - - - Peptidase M50
KMEHGPNO_00445 1.11e-21 csbD - - K - - - CsbD-like
KMEHGPNO_00446 8.2e-68 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
KMEHGPNO_00447 1.12e-83 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
KMEHGPNO_00448 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
KMEHGPNO_00449 4.58e-85 ywnA - - K - - - Transcriptional regulator
KMEHGPNO_00450 2.06e-145 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
KMEHGPNO_00451 1.06e-78 ywnC - - S - - - Family of unknown function (DUF5362)
KMEHGPNO_00452 4.65e-182 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
KMEHGPNO_00453 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KMEHGPNO_00454 7.07e-92 ywnF - - S - - - Family of unknown function (DUF5392)
KMEHGPNO_00455 4.64e-22 ywnC - - S - - - Family of unknown function (DUF5362)
KMEHGPNO_00456 1.49e-114 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
KMEHGPNO_00457 1.85e-161 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
KMEHGPNO_00458 1.63e-95 ywnJ - - S - - - VanZ like family
KMEHGPNO_00459 6.02e-135 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
KMEHGPNO_00460 4.51e-77 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
KMEHGPNO_00461 1.6e-288 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
KMEHGPNO_00462 5.04e-101 - - - - - - - -
KMEHGPNO_00463 3e-133 yjgF - - Q - - - Isochorismatase family
KMEHGPNO_00464 2.67e-307 ywoD - - EGP - - - Major facilitator superfamily
KMEHGPNO_00465 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
KMEHGPNO_00466 4.62e-309 ywoF - - P - - - Right handed beta helix region
KMEHGPNO_00467 1.37e-269 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
KMEHGPNO_00468 8.45e-92 - - - K - - - COG1846 Transcriptional regulators
KMEHGPNO_00469 4.88e-59 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
KMEHGPNO_00470 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
KMEHGPNO_00471 1.77e-172 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
KMEHGPNO_00472 1.17e-181 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
KMEHGPNO_00473 2.59e-255 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
KMEHGPNO_00474 6.89e-107 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KMEHGPNO_00475 5.62e-78 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KMEHGPNO_00476 0.0 ywpD - - T - - - Histidine kinase
KMEHGPNO_00477 1.68e-221 M1-574 - - T - - - Transcriptional regulatory protein, C terminal
KMEHGPNO_00478 0.0 - - - M - - - cell wall anchor domain
KMEHGPNO_00479 1.24e-108 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
KMEHGPNO_00480 8.81e-89 ywpF - - S - - - YwpF-like protein
KMEHGPNO_00481 5.26e-88 ywpG - - - - - - -
KMEHGPNO_00482 8.53e-76 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
KMEHGPNO_00483 4.62e-178 glcR - - K ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
KMEHGPNO_00484 5.07e-200 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
KMEHGPNO_00485 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
KMEHGPNO_00486 0.0 ywqB - - S - - - SWIM zinc finger
KMEHGPNO_00487 3.6e-25 - - - - - - - -
KMEHGPNO_00488 5.33e-163 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
KMEHGPNO_00489 6.13e-152 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
KMEHGPNO_00490 8.34e-179 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
KMEHGPNO_00491 4e-314 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KMEHGPNO_00492 4.19e-196 ywqG - - S - - - Domain of unknown function (DUF1963)
KMEHGPNO_00494 2.17e-52 ywqI - - S - - - Family of unknown function (DUF5344)
KMEHGPNO_00495 3.15e-265 - - - L - - - nucleic acid phosphodiester bond hydrolysis
KMEHGPNO_00496 1.77e-26 - - - - - - - -
KMEHGPNO_00497 1.3e-23 - - - - - - - -
KMEHGPNO_00498 1.86e-94 ywqJ - - S - - - Pre-toxin TG
KMEHGPNO_00499 1.29e-97 - - - - - - - -
KMEHGPNO_00500 2.88e-66 - - - - - - - -
KMEHGPNO_00502 1.71e-30 - - - - - - - -
KMEHGPNO_00503 1.89e-75 - - - - - - - -
KMEHGPNO_00504 2.44e-154 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
KMEHGPNO_00505 1.93e-208 - - - K - - - Transcriptional regulator
KMEHGPNO_00506 9.04e-131 ywqN - - S - - - NAD(P)H-dependent
KMEHGPNO_00507 6.07e-114 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
KMEHGPNO_00508 4.53e-132 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
KMEHGPNO_00509 2.79e-107 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
KMEHGPNO_00510 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
KMEHGPNO_00511 1.13e-70 - - - S - - - Domain of unknown function (DUF4181)
KMEHGPNO_00512 7.22e-142 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KMEHGPNO_00513 1e-17 - - - - - - - -
KMEHGPNO_00514 2.08e-265 cotH - - M ko:K06330 - ko00000 Spore Coat
KMEHGPNO_00515 1.99e-171 cotB - - - ko:K06325 - ko00000 -
KMEHGPNO_00516 2.14e-162 ywrJ - - - - - - -
KMEHGPNO_00517 1.32e-278 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KMEHGPNO_00518 3.36e-218 alsR - - K - - - LysR substrate binding domain
KMEHGPNO_00519 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
KMEHGPNO_00520 1.84e-187 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
KMEHGPNO_00521 3.57e-125 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
KMEHGPNO_00522 3.75e-63 ywsA - - S - - - Protein of unknown function (DUF3892)
KMEHGPNO_00523 9.76e-120 batE - - T - - - Sh3 type 3 domain protein
KMEHGPNO_00524 9.04e-204 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
KMEHGPNO_00525 3.35e-203 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
KMEHGPNO_00526 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
KMEHGPNO_00527 6.55e-84 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
KMEHGPNO_00528 1.25e-204 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KMEHGPNO_00529 1.27e-225 rbsR - - K ko:K02529 - ko00000,ko03000 transcriptional
KMEHGPNO_00530 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
KMEHGPNO_00531 8.44e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
KMEHGPNO_00532 1.1e-276 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
KMEHGPNO_00533 2.29e-29 ywtC - - - - - - -
KMEHGPNO_00534 1.37e-304 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
KMEHGPNO_00535 4.69e-201 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
KMEHGPNO_00536 1.42e-220 ywtF_2 - - K - - - Transcriptional regulator
KMEHGPNO_00537 1.84e-314 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
KMEHGPNO_00538 2.52e-263 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
KMEHGPNO_00539 2.45e-247 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
KMEHGPNO_00540 0.0 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
KMEHGPNO_00541 2.62e-238 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
KMEHGPNO_00542 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KMEHGPNO_00543 0.0 - - - - - - - -
KMEHGPNO_00544 2.1e-270 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KMEHGPNO_00545 1.9e-185 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
KMEHGPNO_00546 3.82e-91 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
KMEHGPNO_00547 0.0 tagE 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferase 1 domain A
KMEHGPNO_00548 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KMEHGPNO_00549 2.06e-194 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
KMEHGPNO_00550 0.0 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
KMEHGPNO_00551 1.78e-208 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
KMEHGPNO_00552 1.56e-276 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KMEHGPNO_00553 1.13e-218 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
KMEHGPNO_00554 3.26e-50 - - - - - - - -
KMEHGPNO_00555 0.0 lytB - - D - - - Stage II sporulation protein
KMEHGPNO_00556 0.0 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
KMEHGPNO_00557 1.49e-143 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
KMEHGPNO_00558 4.13e-315 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KMEHGPNO_00559 4.86e-280 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
KMEHGPNO_00560 0.0 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KMEHGPNO_00561 0.0 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
KMEHGPNO_00562 1.17e-146 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
KMEHGPNO_00563 8.42e-187 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
KMEHGPNO_00564 2.39e-296 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
KMEHGPNO_00565 1.22e-230 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
KMEHGPNO_00566 2.56e-221 yvhJ - - K - - - Transcriptional regulator
KMEHGPNO_00567 2.41e-155 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
KMEHGPNO_00568 2.94e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
KMEHGPNO_00569 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KMEHGPNO_00570 1.77e-198 degV - - S - - - protein conserved in bacteria
KMEHGPNO_00571 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KMEHGPNO_00572 2.97e-60 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
KMEHGPNO_00573 2.26e-162 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
KMEHGPNO_00574 5.26e-96 yvyF - - S - - - flagellar protein
KMEHGPNO_00575 4.32e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
KMEHGPNO_00576 1e-101 yvyG - - NOU - - - FlgN protein
KMEHGPNO_00577 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
KMEHGPNO_00578 5.4e-197 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
KMEHGPNO_00579 1.7e-92 yviE - - - - - - -
KMEHGPNO_00580 1.23e-96 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
KMEHGPNO_00581 1.23e-39 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KMEHGPNO_00582 1.01e-106 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KMEHGPNO_00583 9.02e-76 flaG - - N ko:K06603 - ko00000,ko02035 flagellar protein FlaG
KMEHGPNO_00584 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KMEHGPNO_00585 1.48e-90 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
KMEHGPNO_00586 8.69e-09 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
KMEHGPNO_00587 2.46e-67 - - - - - - - -
KMEHGPNO_00588 2.02e-131 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KMEHGPNO_00589 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KMEHGPNO_00590 5.73e-232 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KMEHGPNO_00591 5.34e-184 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
KMEHGPNO_00592 4.42e-73 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
KMEHGPNO_00593 1.5e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
KMEHGPNO_00594 5.45e-199 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
KMEHGPNO_00595 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
KMEHGPNO_00596 1.38e-73 swrA - - S - - - Swarming motility protein
KMEHGPNO_00597 6.4e-280 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KMEHGPNO_00598 2.48e-294 yvkA - - P - - - -transporter
KMEHGPNO_00599 1.43e-131 yvkB - - K - - - Transcriptional regulator
KMEHGPNO_00600 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
KMEHGPNO_00601 2.54e-42 csbA - - S - - - protein conserved in bacteria
KMEHGPNO_00602 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KMEHGPNO_00603 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KMEHGPNO_00604 3.03e-147 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KMEHGPNO_00605 2.25e-45 yvkN - - - - - - -
KMEHGPNO_00606 8.09e-65 yvlA - - - - - - -
KMEHGPNO_00607 9.59e-220 yvlB - - S - - - Putative adhesin
KMEHGPNO_00608 1.5e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
KMEHGPNO_00609 3.8e-66 yvlD - - S ko:K08972 - ko00000 Membrane
KMEHGPNO_00610 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
KMEHGPNO_00611 8.67e-171 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
KMEHGPNO_00612 3.81e-169 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KMEHGPNO_00613 8.41e-280 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
KMEHGPNO_00614 8.52e-216 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KMEHGPNO_00615 9.11e-195 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KMEHGPNO_00616 5.65e-206 yvoD - - P - - - COG0370 Fe2 transport system protein B
KMEHGPNO_00617 3.05e-153 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
KMEHGPNO_00618 3.58e-119 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
KMEHGPNO_00619 3.15e-153 - 4.2.2.10, 4.2.2.2 - G ko:K19551 ko00040,map00040 ko00000,ko00001,ko01000 Pectate lyase
KMEHGPNO_00620 1.76e-178 yvpB - - NU - - - protein conserved in bacteria
KMEHGPNO_00621 2.42e-281 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KMEHGPNO_00622 1.06e-147 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
KMEHGPNO_00623 3e-291 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KMEHGPNO_00624 1.17e-137 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
KMEHGPNO_00625 5.24e-143 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KMEHGPNO_00626 1.27e-164 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KMEHGPNO_00627 5.63e-176 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
KMEHGPNO_00628 1.82e-141 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
KMEHGPNO_00629 7.13e-117 - - - S - - - Predicted membrane protein (DUF2339)
KMEHGPNO_00630 6.85e-91 - - - - - - - -
KMEHGPNO_00632 9.55e-88 - - - - - - - -
KMEHGPNO_00633 3.26e-95 - - - - - - - -
KMEHGPNO_00634 0.0 - - - - - - - -
KMEHGPNO_00636 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
KMEHGPNO_00637 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
KMEHGPNO_00638 4.66e-186 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
KMEHGPNO_00639 1.18e-225 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KMEHGPNO_00640 2.39e-117 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
KMEHGPNO_00641 8.53e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
KMEHGPNO_00642 6.72e-227 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
KMEHGPNO_00643 1.04e-219 whiA - - K ko:K09762 - ko00000 May be required for sporulation
KMEHGPNO_00644 3.92e-50 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
KMEHGPNO_00645 8.98e-180 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
KMEHGPNO_00646 5.4e-43 - - - - - - - -
KMEHGPNO_00647 1.9e-171 yvcP - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KMEHGPNO_00648 1.08e-248 yvcQ - - T - - - His Kinase A (phosphoacceptor) domain
KMEHGPNO_00649 1.28e-180 yxdL_2 - - V ko:K02003,ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
KMEHGPNO_00650 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
KMEHGPNO_00651 2.7e-233 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KMEHGPNO_00652 8.79e-136 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
KMEHGPNO_00653 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
KMEHGPNO_00654 7.84e-71 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
KMEHGPNO_00655 5.37e-137 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
KMEHGPNO_00656 1.54e-221 yvdE - - K - - - Transcriptional regulator
KMEHGPNO_00657 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, N-terminal ig-like domain
KMEHGPNO_00658 5.95e-302 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
KMEHGPNO_00659 1.67e-308 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
KMEHGPNO_00660 1.96e-189 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
KMEHGPNO_00661 3.55e-200 malA - - S - - - Protein of unknown function (DUF1189)
KMEHGPNO_00662 0.0 yvdK 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
KMEHGPNO_00663 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
KMEHGPNO_00664 2.65e-147 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
KMEHGPNO_00665 8.17e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KMEHGPNO_00667 1.12e-121 yvdQ - - S - - - Protein of unknown function (DUF3231)
KMEHGPNO_00668 1.03e-66 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
KMEHGPNO_00669 6.31e-68 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
KMEHGPNO_00670 1.17e-137 yvdT_1 - - K - - - Transcriptional regulator
KMEHGPNO_00671 0.0 ybeC - - E - - - amino acid
KMEHGPNO_00672 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
KMEHGPNO_00673 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
KMEHGPNO_00674 0.0 pbpE - - V - - - Beta-lactamase
KMEHGPNO_00675 1.51e-163 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
KMEHGPNO_00676 1.75e-93 - - - S - - - Protein of unknown function (DUF3237)
KMEHGPNO_00677 5.4e-120 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
KMEHGPNO_00679 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
KMEHGPNO_00680 3.57e-98 - - - K ko:K19417 - ko00000,ko03000 transcriptional
KMEHGPNO_00681 1.61e-157 epsA - - M ko:K19420 - ko00000 biosynthesis protein
KMEHGPNO_00682 2.28e-149 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
KMEHGPNO_00683 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
KMEHGPNO_00684 7.45e-280 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
KMEHGPNO_00685 1.25e-201 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
KMEHGPNO_00686 2.06e-277 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
KMEHGPNO_00687 2.08e-263 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
KMEHGPNO_00688 2.87e-247 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
KMEHGPNO_00689 1.83e-257 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
KMEHGPNO_00690 1.94e-245 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
KMEHGPNO_00691 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KMEHGPNO_00692 9.14e-139 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
KMEHGPNO_00693 8.22e-77 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
KMEHGPNO_00694 8.7e-278 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
KMEHGPNO_00695 1.91e-234 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
KMEHGPNO_00696 5.69e-44 yvfG - - S - - - YvfG protein
KMEHGPNO_00697 1.73e-306 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
KMEHGPNO_00698 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
KMEHGPNO_00699 2.79e-145 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
KMEHGPNO_00700 2e-236 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
KMEHGPNO_00701 2.19e-290 cycB - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
KMEHGPNO_00702 2.15e-300 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
KMEHGPNO_00703 3.82e-194 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
KMEHGPNO_00704 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 beta-galactosidase
KMEHGPNO_00705 0.0 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
KMEHGPNO_00706 1.52e-265 - 3.1.3.3 - T ko:K07315 - ko00000,ko01000,ko03021 response regulator
KMEHGPNO_00707 2.08e-200 rsbQ - - S ko:K19707 - ko00000,ko03021 Alpha/beta hydrolase family
KMEHGPNO_00709 3.03e-202 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
KMEHGPNO_00710 2.04e-170 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
KMEHGPNO_00711 1.21e-248 yvfT 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KMEHGPNO_00712 1.25e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KMEHGPNO_00713 4.23e-42 - - - K - - - Transcriptional regulator PadR-like family
KMEHGPNO_00714 3.88e-57 - - - S - - - Protein of unknown function (DUF2812)
KMEHGPNO_00715 9.08e-175 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
KMEHGPNO_00716 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
KMEHGPNO_00717 2.4e-171 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
KMEHGPNO_00718 1.73e-248 - - - S - - - Glycosyl hydrolase
KMEHGPNO_00719 7.07e-307 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
KMEHGPNO_00720 7.93e-198 yvbV - - EG - - - EamA-like transporter family
KMEHGPNO_00721 3.45e-206 yvbU - - K - - - Transcriptional regulator
KMEHGPNO_00722 2.98e-245 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KMEHGPNO_00723 1.51e-258 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
KMEHGPNO_00724 0.0 araE - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
KMEHGPNO_00725 5.69e-236 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
KMEHGPNO_00726 5.72e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KMEHGPNO_00727 1.97e-277 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
KMEHGPNO_00728 2.12e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KMEHGPNO_00729 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
KMEHGPNO_00730 1.38e-309 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KMEHGPNO_00731 9.77e-106 yvbK - - K - - - acetyltransferase
KMEHGPNO_00732 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
KMEHGPNO_00733 1.61e-156 yvbI - - M - - - Membrane
KMEHGPNO_00734 4.91e-144 yvbH - - S - - - YvbH-like oligomerisation region
KMEHGPNO_00735 1.37e-135 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
KMEHGPNO_00736 4.8e-128 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
KMEHGPNO_00737 5.58e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
KMEHGPNO_00738 5.63e-145 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
KMEHGPNO_00739 3.52e-221 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
KMEHGPNO_00740 1.13e-135 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
KMEHGPNO_00741 6.63e-122 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
KMEHGPNO_00742 3.64e-271 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
KMEHGPNO_00743 1.27e-141 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
KMEHGPNO_00744 4.78e-220 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
KMEHGPNO_00745 2.48e-134 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
KMEHGPNO_00746 1.04e-231 bsaB - - S ko:K20483 ko02020,ko02024,map02020,map02024 ko00000,ko00001 Lantibiotic dehydratase, C terminus
KMEHGPNO_00747 8.57e-193 - - - V ko:K06147,ko:K06148,ko:K20485 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 ABC transporter
KMEHGPNO_00748 8.33e-95 spaC1 - - V ko:K20484 ko02020,ko02024,map02020,map02024 ko00000,ko00001 Lanthionine synthetase C-like protein
KMEHGPNO_00751 7.1e-131 spaF - - V ko:K01990,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
KMEHGPNO_00752 1.67e-110 spaE - - S ko:K20491 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
KMEHGPNO_00753 1.49e-103 spaG - - S ko:K20492 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
KMEHGPNO_00754 1.41e-135 spaR - - K ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
KMEHGPNO_00755 1.43e-195 spaK 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
KMEHGPNO_00756 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
KMEHGPNO_00757 3.85e-72 yvaP - - K - - - transcriptional
KMEHGPNO_00758 9.82e-92 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
KMEHGPNO_00759 4.08e-92 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
KMEHGPNO_00760 4.9e-48 yvzC - - K - - - transcriptional
KMEHGPNO_00761 1.71e-195 yvaM 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Serine aminopeptidase, S33
KMEHGPNO_00762 1.87e-35 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
KMEHGPNO_00763 1.99e-182 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
KMEHGPNO_00764 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KMEHGPNO_00765 2.4e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KMEHGPNO_00767 3.96e-182 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
KMEHGPNO_00768 1.66e-126 - - - K - - - Bacterial regulatory proteins, tetR family
KMEHGPNO_00769 5.85e-70 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
KMEHGPNO_00770 2.02e-97 yvaD - - S - - - Family of unknown function (DUF5360)
KMEHGPNO_00771 0.0 - - - S - - - Fusaric acid resistance protein-like
KMEHGPNO_00772 5.09e-154 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KMEHGPNO_00773 2.83e-247 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
KMEHGPNO_00774 6.89e-65 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
KMEHGPNO_00775 3.66e-41 copZ - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Copper resistance protein CopZ
KMEHGPNO_00776 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
KMEHGPNO_00777 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
KMEHGPNO_00778 3.45e-137 bdbD - - O - - - Thioredoxin
KMEHGPNO_00779 1.99e-95 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
KMEHGPNO_00780 2.34e-139 yvgT - - S - - - membrane
KMEHGPNO_00782 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
KMEHGPNO_00783 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KMEHGPNO_00784 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
KMEHGPNO_00785 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
KMEHGPNO_00786 7.97e-113 yvgO - - - - - - -
KMEHGPNO_00787 6.19e-201 yvgN - - S - - - reductase
KMEHGPNO_00788 2.89e-152 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
KMEHGPNO_00789 1.22e-174 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
KMEHGPNO_00790 6.98e-212 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
KMEHGPNO_00791 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
KMEHGPNO_00792 2.38e-109 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
KMEHGPNO_00793 9.37e-23 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
KMEHGPNO_00794 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
KMEHGPNO_00796 4.45e-225 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KMEHGPNO_00797 2e-235 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KMEHGPNO_00798 4.78e-226 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KMEHGPNO_00799 2.92e-191 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
KMEHGPNO_00800 3.61e-231 - - - M ko:K02005 - ko00000 Efflux transporter rnd family, mfp subunit
KMEHGPNO_00801 1.09e-157 yvrO - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KMEHGPNO_00802 4.45e-272 yvrN - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
KMEHGPNO_00803 9.89e-86 yvrL - - S - - - Regulatory protein YrvL
KMEHGPNO_00804 3.76e-291 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
KMEHGPNO_00805 3.46e-26 - - - S - - - YvrJ protein family
KMEHGPNO_00806 7.02e-128 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
KMEHGPNO_00807 8.75e-33 - - - - - - - -
KMEHGPNO_00808 1.1e-170 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KMEHGPNO_00809 0.0 yvrG - - T - - - Histidine kinase
KMEHGPNO_00810 1.32e-219 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
KMEHGPNO_00811 1.23e-180 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
KMEHGPNO_00812 3.48e-217 btuF - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
KMEHGPNO_00813 1.56e-235 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KMEHGPNO_00814 1.49e-308 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
KMEHGPNO_00815 2.96e-130 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
KMEHGPNO_00816 6.23e-286 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
KMEHGPNO_00817 6.17e-82 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
KMEHGPNO_00818 9.94e-143 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
KMEHGPNO_00819 1.41e-172 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
KMEHGPNO_00820 6.29e-163 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
KMEHGPNO_00821 3.89e-244 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KMEHGPNO_00822 4.46e-139 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KMEHGPNO_00823 6.16e-243 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
KMEHGPNO_00824 3.94e-251 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
KMEHGPNO_00825 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
KMEHGPNO_00826 4.48e-34 - - - S - - - Protein of unknown function (DUF3970)
KMEHGPNO_00827 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
KMEHGPNO_00828 8.77e-204 yuxN - - K - - - Transcriptional regulator
KMEHGPNO_00829 0.0 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KMEHGPNO_00830 2.23e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KMEHGPNO_00831 1.12e-304 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KMEHGPNO_00832 2.15e-104 fri - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
KMEHGPNO_00833 1.75e-193 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
KMEHGPNO_00834 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
KMEHGPNO_00835 3.48e-88 - - - S - - - YusW-like protein
KMEHGPNO_00836 2.51e-195 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
KMEHGPNO_00837 3.99e-53 yusU - - S - - - Protein of unknown function (DUF2573)
KMEHGPNO_00838 6.91e-203 gltR - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
KMEHGPNO_00839 1.22e-138 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
KMEHGPNO_00840 1.02e-85 yusQ - - S - - - Tautomerase enzyme
KMEHGPNO_00841 0.0 yusP - - P - - - Major facilitator superfamily
KMEHGPNO_00842 1.05e-96 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
KMEHGPNO_00843 8.66e-70 yusN - - M - - - Coat F domain
KMEHGPNO_00844 2.23e-54 - - - - - - - -
KMEHGPNO_00845 8.15e-210 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
KMEHGPNO_00846 1.11e-13 - - - S - - - YuzL-like protein
KMEHGPNO_00847 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
KMEHGPNO_00848 1.34e-278 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
KMEHGPNO_00849 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
KMEHGPNO_00850 1.01e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
KMEHGPNO_00851 5.91e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
KMEHGPNO_00852 7.34e-54 yusG - - S - - - Protein of unknown function (DUF2553)
KMEHGPNO_00853 7.62e-97 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
KMEHGPNO_00854 5.73e-73 yusE - - CO - - - Thioredoxin
KMEHGPNO_00855 1.53e-74 yusD - - S - - - SCP-2 sterol transfer family
KMEHGPNO_00856 2.5e-235 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KMEHGPNO_00857 6.5e-126 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
KMEHGPNO_00858 5.86e-189 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
KMEHGPNO_00859 1.56e-80 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KMEHGPNO_00860 4.46e-182 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
KMEHGPNO_00861 6.1e-312 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
KMEHGPNO_00862 1.14e-298 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KMEHGPNO_00863 6.26e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
KMEHGPNO_00864 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
KMEHGPNO_00865 5.06e-86 yurT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KMEHGPNO_00866 3.35e-56 - - - - - - - -
KMEHGPNO_00868 1.59e-265 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
KMEHGPNO_00869 1.2e-87 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
KMEHGPNO_00870 5.27e-235 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
KMEHGPNO_00871 1.93e-305 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
KMEHGPNO_00872 3.54e-199 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KMEHGPNO_00873 1.94e-216 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
KMEHGPNO_00874 1.3e-206 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
KMEHGPNO_00875 8.71e-175 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
KMEHGPNO_00876 8.1e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KMEHGPNO_00877 6.27e-216 bsn - - L - - - Ribonuclease
KMEHGPNO_00878 6.56e-292 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
KMEHGPNO_00879 1.3e-300 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
KMEHGPNO_00880 4.85e-232 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
KMEHGPNO_00881 3.58e-142 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
KMEHGPNO_00882 8.63e-188 pucC 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03519 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
KMEHGPNO_00883 0.0 pucD 1.17.1.4 - C ko:K00087 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
KMEHGPNO_00884 2.42e-122 - 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03518 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
KMEHGPNO_00885 0.000154 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
KMEHGPNO_00886 4.38e-74 pucM 3.5.2.17 - S ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
KMEHGPNO_00887 0.0 - 1.7.3.3, 4.1.1.97 - Q ko:K16838 ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
KMEHGPNO_00888 9.52e-285 pbuX - - F ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
KMEHGPNO_00889 1.82e-294 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 Permease family
KMEHGPNO_00890 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
KMEHGPNO_00891 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
KMEHGPNO_00892 1.07e-79 yunG - - - - - - -
KMEHGPNO_00893 4.26e-220 yunF - - S - - - Protein of unknown function DUF72
KMEHGPNO_00894 2.65e-180 yunE - - S ko:K07090 - ko00000 membrane transporter protein
KMEHGPNO_00895 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
KMEHGPNO_00896 1.39e-64 yunC - - S - - - Domain of unknown function (DUF1805)
KMEHGPNO_00897 3.49e-169 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
KMEHGPNO_00898 7.63e-252 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
KMEHGPNO_00899 1.37e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KMEHGPNO_00900 1.34e-144 yutC - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KMEHGPNO_00901 3.2e-63 yutD - - S - - - protein conserved in bacteria
KMEHGPNO_00902 1.96e-98 yutE - - S - - - Protein of unknown function DUF86
KMEHGPNO_00903 3.69e-183 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KMEHGPNO_00904 2.26e-101 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
KMEHGPNO_00905 4.98e-252 yutH - - S - - - Spore coat protein
KMEHGPNO_00906 6.79e-307 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
KMEHGPNO_00907 6.87e-253 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KMEHGPNO_00908 2.57e-221 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KMEHGPNO_00909 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
KMEHGPNO_00910 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
KMEHGPNO_00911 2.7e-74 yuzD - - S - - - protein conserved in bacteria
KMEHGPNO_00912 1.12e-253 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
KMEHGPNO_00913 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
KMEHGPNO_00914 6.25e-270 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KMEHGPNO_00915 3.9e-208 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KMEHGPNO_00916 6.81e-83 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
KMEHGPNO_00917 8.44e-118 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KMEHGPNO_00918 2.84e-149 paiB - - K ko:K07734 - ko00000,ko03000 Putative FMN-binding domain
KMEHGPNO_00919 6.4e-235 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KMEHGPNO_00921 3.32e-240 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
KMEHGPNO_00922 1.7e-300 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
KMEHGPNO_00923 2.8e-46 yuiB - - S - - - Putative membrane protein
KMEHGPNO_00924 1.39e-150 yuiC - - S - - - protein conserved in bacteria
KMEHGPNO_00925 8.63e-102 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
KMEHGPNO_00926 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KMEHGPNO_00927 3.65e-279 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
KMEHGPNO_00928 8.33e-125 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
KMEHGPNO_00929 2.36e-157 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
KMEHGPNO_00930 1.26e-211 eSD - - S ko:K07017 - ko00000 Putative esterase
KMEHGPNO_00931 4.1e-178 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
KMEHGPNO_00932 1.22e-289 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
KMEHGPNO_00933 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
KMEHGPNO_00934 3.15e-228 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
KMEHGPNO_00935 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KMEHGPNO_00936 2.02e-47 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
KMEHGPNO_00937 1.2e-168 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
KMEHGPNO_00938 1.64e-261 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
KMEHGPNO_00939 2.84e-290 yukF - - QT - - - Transcriptional regulator
KMEHGPNO_00940 3.93e-60 yukE - - S - - - Belongs to the WXG100 family
KMEHGPNO_00941 1.93e-54 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
KMEHGPNO_00942 8.62e-271 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
KMEHGPNO_00943 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
KMEHGPNO_00944 0.0 yueB - - S - - - type VII secretion protein EsaA
KMEHGPNO_00945 1.78e-96 yueC - - S - - - Family of unknown function (DUF5383)
KMEHGPNO_00946 1.68e-168 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KMEHGPNO_00947 1.91e-125 yueE - - S ko:K06950 - ko00000 phosphohydrolase
KMEHGPNO_00948 8.4e-33 - - - S - - - Protein of unknown function (DUF2642)
KMEHGPNO_00949 3.82e-91 - - - S - - - Protein of unknown function (DUF2283)
KMEHGPNO_00950 1.35e-244 yueF - - S - - - transporter activity
KMEHGPNO_00951 7.15e-43 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
KMEHGPNO_00952 1.63e-52 yueH - - S - - - YueH-like protein
KMEHGPNO_00953 8.92e-87 - - - S - - - Protein of unknown function (DUF1694)
KMEHGPNO_00954 4.46e-132 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
KMEHGPNO_00955 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KMEHGPNO_00956 2.92e-298 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
KMEHGPNO_00957 4.38e-09 yuzC - - - - - - -
KMEHGPNO_00958 6.29e-10 - - - S - - - DegQ (SacQ) family
KMEHGPNO_00959 2.85e-182 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Belongs to the FPP GGPP synthase family
KMEHGPNO_00961 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KMEHGPNO_00962 2.06e-150 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KMEHGPNO_00963 1.11e-82 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
KMEHGPNO_00964 1.41e-77 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
KMEHGPNO_00965 2.23e-51 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KMEHGPNO_00966 2.12e-102 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KMEHGPNO_00967 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KMEHGPNO_00968 1.72e-66 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KMEHGPNO_00969 7.66e-91 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KMEHGPNO_00970 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
KMEHGPNO_00971 2.46e-22 - - - - - - - -
KMEHGPNO_00972 7.99e-309 malP - - C ko:K11616 ko02020,map02020 ko00000,ko00001 COG3493 Na citrate symporter
KMEHGPNO_00973 1.71e-215 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
KMEHGPNO_00974 6.39e-237 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
KMEHGPNO_00975 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KMEHGPNO_00976 5.28e-246 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
KMEHGPNO_00977 7.68e-161 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
KMEHGPNO_00978 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
KMEHGPNO_00979 4.19e-113 yufK - - S - - - Family of unknown function (DUF5366)
KMEHGPNO_00980 1.92e-97 yuxK - - S - - - protein conserved in bacteria
KMEHGPNO_00981 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
KMEHGPNO_00982 4.61e-244 yuxJ - - EGP - - - Major facilitator superfamily
KMEHGPNO_00984 8.49e-150 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
KMEHGPNO_00985 8.69e-92 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
KMEHGPNO_00986 7.15e-295 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KMEHGPNO_00987 2.44e-288 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
KMEHGPNO_00988 8.84e-52 yugE - - S - - - Domain of unknown function (DUF1871)
KMEHGPNO_00989 2.72e-198 yugF - - I - - - Hydrolase
KMEHGPNO_00990 6.74e-112 alaR - - K - - - Transcriptional regulator
KMEHGPNO_00991 5.43e-255 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
KMEHGPNO_00992 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
KMEHGPNO_00993 2.21e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
KMEHGPNO_00994 2.85e-287 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
KMEHGPNO_00995 9.22e-290 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
KMEHGPNO_00996 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
KMEHGPNO_00998 4.22e-95 yugN - - S - - - YugN-like family
KMEHGPNO_00999 3.56e-233 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
KMEHGPNO_01000 5.01e-69 mstX - - S - - - Membrane-integrating protein Mistic
KMEHGPNO_01001 1.58e-50 - - - - - - - -
KMEHGPNO_01002 4.8e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
KMEHGPNO_01003 8.8e-301 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
KMEHGPNO_01004 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
KMEHGPNO_01005 3.63e-95 yugU - - S - - - Uncharacterised protein family UPF0047
KMEHGPNO_01006 5e-48 - - - - - - - -
KMEHGPNO_01007 6.15e-181 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
KMEHGPNO_01008 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
KMEHGPNO_01009 6.34e-300 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
KMEHGPNO_01010 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
KMEHGPNO_01011 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
KMEHGPNO_01012 0.0 yuxG - - IQ - - - Class II Aldolase and Adducin N-terminal domain
KMEHGPNO_01013 5.79e-172 yulB - - K ko:K02530,ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
KMEHGPNO_01014 0.0 rhaB 2.7.1.5 - G ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
KMEHGPNO_01015 4.94e-73 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
KMEHGPNO_01016 9.8e-317 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Belongs to the rhamnose isomerase family
KMEHGPNO_01017 7.48e-235 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
KMEHGPNO_01018 8.95e-255 yubA - - S - - - transporter activity
KMEHGPNO_01019 4.06e-181 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KMEHGPNO_01021 3.95e-113 cdoA 1.13.11.20 - S ko:K00456 ko00270,ko00430,ko01100,map00270,map00430,map01100 ko00000,ko00001,ko01000 Cysteine dioxygenase type I
KMEHGPNO_01022 0.0 yubD - - P - - - Major Facilitator Superfamily
KMEHGPNO_01023 3.09e-195 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KMEHGPNO_01024 3.31e-52 yubF - - S - - - yiaA/B two helix domain
KMEHGPNO_01025 4.35e-300 - - - P ko:K03498 - ko00000,ko02000 Potassium
KMEHGPNO_01026 1.06e-156 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
KMEHGPNO_01027 5.83e-118 yuaB - - - - - - -
KMEHGPNO_01028 2.39e-121 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
KMEHGPNO_01029 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
KMEHGPNO_01030 2.46e-291 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
KMEHGPNO_01031 1.66e-136 yuaD - - - - - - -
KMEHGPNO_01032 1.95e-109 yuaE - - S - - - DinB superfamily
KMEHGPNO_01033 1.33e-106 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
KMEHGPNO_01034 5.27e-257 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
KMEHGPNO_01035 1.64e-120 - - - M - - - FR47-like protein
KMEHGPNO_01036 2.52e-122 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
KMEHGPNO_01040 4.94e-13 - - - - - - - -
KMEHGPNO_01041 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
KMEHGPNO_01042 9.94e-90 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
KMEHGPNO_01043 1.67e-310 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
KMEHGPNO_01044 4.47e-294 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KMEHGPNO_01045 2.29e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
KMEHGPNO_01046 2.72e-148 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
KMEHGPNO_01047 4.51e-141 - - - - - - - -
KMEHGPNO_01048 1.65e-243 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KMEHGPNO_01049 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KMEHGPNO_01050 5.01e-66 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
KMEHGPNO_01051 1.2e-30 ymzA - - - - - - -
KMEHGPNO_01052 1.63e-31 - - - - - - - -
KMEHGPNO_01053 1.28e-45 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
KMEHGPNO_01054 1.38e-223 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KMEHGPNO_01055 5.41e-76 ymaF - - S - - - YmaF family
KMEHGPNO_01057 5.79e-66 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
KMEHGPNO_01058 6.39e-73 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 COG2076 Membrane transporters of cations and cationic drugs
KMEHGPNO_01059 5.98e-105 ymaD - - O - - - redox protein, regulator of disulfide bond formation
KMEHGPNO_01060 1.14e-162 ymaC - - S - - - Replication protein
KMEHGPNO_01062 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
KMEHGPNO_01063 1.09e-206 - - - S - - - Metallo-beta-lactamase superfamily
KMEHGPNO_01064 9.39e-80 ymzB - - - - - - -
KMEHGPNO_01065 8.33e-296 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
KMEHGPNO_01066 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
KMEHGPNO_01067 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
KMEHGPNO_01068 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
KMEHGPNO_01069 0.0 - - - Q ko:K13612 - ko00000,ko01004,ko01008 Polyketide synthase of type I
KMEHGPNO_01070 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
KMEHGPNO_01071 4.47e-176 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
KMEHGPNO_01072 2.78e-181 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
KMEHGPNO_01073 5.61e-313 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
KMEHGPNO_01074 3.07e-303 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KMEHGPNO_01075 5.46e-51 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
KMEHGPNO_01076 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
KMEHGPNO_01077 2.14e-232 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
KMEHGPNO_01079 1.25e-206 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
KMEHGPNO_01080 2.71e-165 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
KMEHGPNO_01081 2.32e-138 pksA - - K - - - Transcriptional regulator
KMEHGPNO_01082 9.3e-126 ymcC - - S - - - Membrane
KMEHGPNO_01084 6.4e-90 - - - S - - - Regulatory protein YrvL
KMEHGPNO_01085 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KMEHGPNO_01086 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KMEHGPNO_01087 1.74e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
KMEHGPNO_01088 1.27e-89 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
KMEHGPNO_01089 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KMEHGPNO_01090 4.84e-277 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
KMEHGPNO_01091 3.38e-252 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
KMEHGPNO_01092 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
KMEHGPNO_01093 6.18e-195 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
KMEHGPNO_01094 4.25e-306 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
KMEHGPNO_01095 3.84e-278 pbpX - - V - - - Beta-lactamase
KMEHGPNO_01096 2.72e-238 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KMEHGPNO_01097 1.06e-299 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
KMEHGPNO_01098 3.34e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KMEHGPNO_01099 8.75e-177 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
KMEHGPNO_01100 3.91e-183 ymfK - - S - - - Protein of unknown function (DUF3388)
KMEHGPNO_01101 5.13e-55 ymfJ - - S - - - Protein of unknown function (DUF3243)
KMEHGPNO_01102 3.01e-166 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
KMEHGPNO_01103 1.37e-308 ymfH - - S - - - zinc protease
KMEHGPNO_01104 1.1e-297 albE - - S - - - Peptidase M16
KMEHGPNO_01105 5.1e-266 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
KMEHGPNO_01106 1.28e-171 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
KMEHGPNO_01107 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
KMEHGPNO_01108 4.94e-44 - - - S - - - YlzJ-like protein
KMEHGPNO_01109 5.01e-171 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
KMEHGPNO_01110 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KMEHGPNO_01111 6.39e-201 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KMEHGPNO_01112 4.9e-283 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
KMEHGPNO_01113 1.66e-247 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KMEHGPNO_01114 8.17e-141 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
KMEHGPNO_01115 5.3e-208 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
KMEHGPNO_01116 1.53e-56 ymxH - - S - - - YlmC YmxH family
KMEHGPNO_01117 1.62e-295 mlpA - - S - - - Belongs to the peptidase M16 family
KMEHGPNO_01118 3.98e-230 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
KMEHGPNO_01119 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
KMEHGPNO_01120 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KMEHGPNO_01121 1.1e-230 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
KMEHGPNO_01122 2.46e-219 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KMEHGPNO_01123 3.29e-75 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KMEHGPNO_01124 1.11e-59 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
KMEHGPNO_01125 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KMEHGPNO_01126 6.16e-63 ylxQ - - J - - - ribosomal protein
KMEHGPNO_01127 2.01e-57 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
KMEHGPNO_01128 5.49e-261 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
KMEHGPNO_01129 1.34e-104 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
KMEHGPNO_01130 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KMEHGPNO_01131 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KMEHGPNO_01132 6.84e-294 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
KMEHGPNO_01133 1.39e-276 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
KMEHGPNO_01134 3.33e-178 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
KMEHGPNO_01135 3.84e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KMEHGPNO_01136 9.6e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KMEHGPNO_01137 5.82e-163 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
KMEHGPNO_01138 4e-201 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KMEHGPNO_01139 1.49e-168 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
KMEHGPNO_01140 1.15e-99 ylxL - - - - - - -
KMEHGPNO_01141 1.33e-175 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KMEHGPNO_01142 3.34e-112 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
KMEHGPNO_01143 5.06e-144 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
KMEHGPNO_01144 9.03e-103 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
KMEHGPNO_01145 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
KMEHGPNO_01146 1.81e-252 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
KMEHGPNO_01147 1.55e-200 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
KMEHGPNO_01148 5.65e-256 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
KMEHGPNO_01149 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KMEHGPNO_01150 6.38e-240 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KMEHGPNO_01151 1.47e-170 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
KMEHGPNO_01152 5.23e-50 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
KMEHGPNO_01153 1.21e-141 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
KMEHGPNO_01154 1.39e-130 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
KMEHGPNO_01155 1.22e-76 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
KMEHGPNO_01156 3.94e-253 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KMEHGPNO_01157 6.61e-231 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
KMEHGPNO_01158 5.59e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
KMEHGPNO_01159 1.09e-179 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
KMEHGPNO_01160 2.81e-96 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
KMEHGPNO_01161 6.14e-303 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
KMEHGPNO_01162 1.51e-78 ylxF - - S - - - MgtE intracellular N domain
KMEHGPNO_01163 1.79e-91 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
KMEHGPNO_01164 3.5e-307 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
KMEHGPNO_01165 9.51e-145 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
KMEHGPNO_01166 6.08e-230 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
KMEHGPNO_01167 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
KMEHGPNO_01168 5.5e-53 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
KMEHGPNO_01169 1.2e-95 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
KMEHGPNO_01170 1.62e-83 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
KMEHGPNO_01171 1.95e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KMEHGPNO_01172 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KMEHGPNO_01173 3.01e-120 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KMEHGPNO_01174 1.13e-217 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
KMEHGPNO_01175 5.45e-314 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KMEHGPNO_01176 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KMEHGPNO_01177 3.62e-215 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
KMEHGPNO_01178 3.09e-213 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KMEHGPNO_01179 1.94e-268 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
KMEHGPNO_01180 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
KMEHGPNO_01181 0.0 ylqG - - - - - - -
KMEHGPNO_01182 2.04e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KMEHGPNO_01183 5.7e-200 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KMEHGPNO_01184 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KMEHGPNO_01185 2.41e-177 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
KMEHGPNO_01186 1.84e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KMEHGPNO_01187 3.41e-80 ylqD - - S - - - YlqD protein
KMEHGPNO_01188 1.2e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
KMEHGPNO_01189 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
KMEHGPNO_01190 3.95e-308 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KMEHGPNO_01191 5.64e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KMEHGPNO_01192 1.67e-114 - - - - - - - -
KMEHGPNO_01193 3.38e-227 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KMEHGPNO_01194 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
KMEHGPNO_01195 2.12e-174 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KMEHGPNO_01196 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
KMEHGPNO_01197 7.07e-167 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
KMEHGPNO_01198 3.76e-218 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
KMEHGPNO_01199 1.68e-229 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KMEHGPNO_01200 6.22e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
KMEHGPNO_01201 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KMEHGPNO_01202 3.4e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
KMEHGPNO_01203 1.45e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
KMEHGPNO_01204 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
KMEHGPNO_01205 3.65e-78 yloU - - S - - - protein conserved in bacteria
KMEHGPNO_01206 7.06e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
KMEHGPNO_01207 2.72e-155 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
KMEHGPNO_01208 4.68e-153 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
KMEHGPNO_01209 1.12e-214 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KMEHGPNO_01210 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
KMEHGPNO_01211 3.54e-180 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
KMEHGPNO_01212 2.16e-263 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
KMEHGPNO_01213 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KMEHGPNO_01214 1.05e-224 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KMEHGPNO_01215 4.8e-109 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KMEHGPNO_01216 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KMEHGPNO_01217 4.21e-285 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KMEHGPNO_01218 6.21e-39 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KMEHGPNO_01219 5.73e-143 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
KMEHGPNO_01220 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
KMEHGPNO_01221 2.41e-201 yloC - - S - - - stress-induced protein
KMEHGPNO_01222 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
KMEHGPNO_01223 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
KMEHGPNO_01224 7.63e-107 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
KMEHGPNO_01225 2.4e-186 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
KMEHGPNO_01226 1.02e-185 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
KMEHGPNO_01227 1.31e-140 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
KMEHGPNO_01228 1.07e-284 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
KMEHGPNO_01229 1.04e-229 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
KMEHGPNO_01230 5.95e-182 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
KMEHGPNO_01231 8.96e-149 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KMEHGPNO_01232 6.56e-164 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KMEHGPNO_01233 8.96e-223 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KMEHGPNO_01234 7.44e-183 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
KMEHGPNO_01235 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
KMEHGPNO_01236 3.76e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
KMEHGPNO_01237 9.71e-317 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KMEHGPNO_01238 2.54e-214 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
KMEHGPNO_01239 2.24e-295 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
KMEHGPNO_01240 4.45e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KMEHGPNO_01241 2.04e-224 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
KMEHGPNO_01242 2.71e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KMEHGPNO_01243 9.18e-83 ylyA - - T - - - COG1734 DnaK suppressor protein
KMEHGPNO_01244 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KMEHGPNO_01245 6.44e-100 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
KMEHGPNO_01246 1.49e-178 ylmH - - S - - - conserved protein, contains S4-like domain
KMEHGPNO_01247 1.22e-53 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
KMEHGPNO_01248 1.28e-86 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KMEHGPNO_01249 3.68e-161 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KMEHGPNO_01250 9.17e-204 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
KMEHGPNO_01251 3.58e-51 ylmC - - S - - - sporulation protein
KMEHGPNO_01252 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
KMEHGPNO_01253 1.1e-188 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
KMEHGPNO_01254 7.99e-180 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KMEHGPNO_01255 1.48e-160 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KMEHGPNO_01256 1.23e-219 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
KMEHGPNO_01257 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
KMEHGPNO_01258 1.84e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KMEHGPNO_01259 4.88e-299 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KMEHGPNO_01260 5.37e-76 sbp - - S - - - small basic protein
KMEHGPNO_01261 1.06e-132 ylxX - - S - - - protein conserved in bacteria
KMEHGPNO_01262 1.35e-143 ylxW - - S - - - protein conserved in bacteria
KMEHGPNO_01263 6.8e-178 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KMEHGPNO_01264 1.3e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
KMEHGPNO_01265 7.74e-257 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KMEHGPNO_01266 6.64e-237 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
KMEHGPNO_01267 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KMEHGPNO_01268 9.59e-220 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KMEHGPNO_01269 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KMEHGPNO_01270 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
KMEHGPNO_01271 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
KMEHGPNO_01272 3.42e-68 ftsL - - D - - - Essential cell division protein
KMEHGPNO_01273 1.66e-218 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KMEHGPNO_01274 9.82e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
KMEHGPNO_01275 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
KMEHGPNO_01276 1.12e-214 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KMEHGPNO_01277 2.68e-115 ylbP - - K - - - n-acetyltransferase
KMEHGPNO_01278 4.72e-107 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
KMEHGPNO_01279 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
KMEHGPNO_01280 6.94e-117 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
KMEHGPNO_01282 1.75e-293 ylbM - - S - - - Belongs to the UPF0348 family
KMEHGPNO_01283 4.52e-238 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
KMEHGPNO_01284 1.48e-175 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
KMEHGPNO_01285 9.11e-281 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
KMEHGPNO_01286 3.8e-111 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KMEHGPNO_01287 6.07e-126 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
KMEHGPNO_01288 4.36e-52 ylbG - - S - - - UPF0298 protein
KMEHGPNO_01289 2.34e-97 ylbF - - S - - - Belongs to the UPF0342 family
KMEHGPNO_01290 1.73e-48 ylbE - - S - - - YlbE-like protein
KMEHGPNO_01291 2.66e-88 ylbD - - S - - - Putative coat protein
KMEHGPNO_01292 2.09e-254 ylbC - - S - - - protein with SCP PR1 domains
KMEHGPNO_01293 1.08e-97 ylbB - - T - - - COG0517 FOG CBS domain
KMEHGPNO_01294 1.61e-81 ylbA - - S - - - YugN-like family
KMEHGPNO_01295 2.01e-212 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
KMEHGPNO_01296 6.09e-70 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
KMEHGPNO_01297 1.84e-145 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
KMEHGPNO_01298 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KMEHGPNO_01299 2.38e-252 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
KMEHGPNO_01300 1.7e-208 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
KMEHGPNO_01301 2.85e-212 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
KMEHGPNO_01302 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KMEHGPNO_01303 2.87e-270 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
KMEHGPNO_01304 6.94e-59 ylaN - - S - - - Belongs to the UPF0358 family
KMEHGPNO_01305 3.49e-219 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
KMEHGPNO_01306 9.32e-112 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KMEHGPNO_01307 3.76e-316 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
KMEHGPNO_01308 9.93e-126 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KMEHGPNO_01309 3.64e-43 ylaI - - S - - - protein conserved in bacteria
KMEHGPNO_01310 4.4e-63 ylaH - - S - - - YlaH-like protein
KMEHGPNO_01311 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
KMEHGPNO_01312 1.56e-30 - - - S - - - Family of unknown function (DUF5325)
KMEHGPNO_01313 5.7e-56 ylaE - - - - - - -
KMEHGPNO_01315 8.39e-114 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
KMEHGPNO_01316 3.39e-55 ylaB - - - - - - -
KMEHGPNO_01317 0.0 ylaA - - - - - - -
KMEHGPNO_01318 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
KMEHGPNO_01319 1.01e-220 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KMEHGPNO_01320 4.07e-98 ykzC - - S - - - Acetyltransferase (GNAT) family
KMEHGPNO_01321 4.33e-191 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
KMEHGPNO_01322 4.48e-35 ykzI - - - - - - -
KMEHGPNO_01323 2.15e-151 yktB - - S - - - Belongs to the UPF0637 family
KMEHGPNO_01324 1.34e-56 yktA - - S - - - Belongs to the UPF0223 family
KMEHGPNO_01325 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
KMEHGPNO_01326 4.55e-83 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
KMEHGPNO_01327 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KMEHGPNO_01328 1.47e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KMEHGPNO_01329 3.52e-227 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KMEHGPNO_01330 1.06e-258 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KMEHGPNO_01331 3.53e-137 ykyA - - L - - - Putative cell-wall binding lipoprotein
KMEHGPNO_01332 2.24e-19 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
KMEHGPNO_01333 3.96e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KMEHGPNO_01334 6.8e-186 ykrA - - S - - - hydrolases of the HAD superfamily
KMEHGPNO_01335 8.98e-42 ykzG - - S - - - Belongs to the UPF0356 family
KMEHGPNO_01336 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KMEHGPNO_01337 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KMEHGPNO_01338 1.68e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
KMEHGPNO_01339 3.42e-198 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
KMEHGPNO_01340 4.59e-307 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
KMEHGPNO_01341 2.63e-58 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
KMEHGPNO_01342 6.17e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
KMEHGPNO_01343 1.09e-18 - - - S - - - Uncharacterized protein YkpC
KMEHGPNO_01344 5.94e-303 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
KMEHGPNO_01345 6.74e-214 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KMEHGPNO_01346 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KMEHGPNO_01347 5.43e-52 ykoA - - - - - - -
KMEHGPNO_01348 1.72e-134 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
KMEHGPNO_01349 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
KMEHGPNO_01350 4.07e-215 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
KMEHGPNO_01351 7.41e-176 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
KMEHGPNO_01352 4.52e-264 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
KMEHGPNO_01353 6.1e-160 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KMEHGPNO_01354 1.92e-232 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KMEHGPNO_01355 8.48e-147 yknW - - S - - - Yip1 domain
KMEHGPNO_01356 0.0 yknV - - V ko:K02021,ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
KMEHGPNO_01357 0.0 yknU - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
KMEHGPNO_01358 2.82e-44 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KMEHGPNO_01359 1.1e-108 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
KMEHGPNO_01360 8.11e-121 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
KMEHGPNO_01361 1.01e-311 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
KMEHGPNO_01362 7.59e-245 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
KMEHGPNO_01363 2.17e-140 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
KMEHGPNO_01364 2.83e-199 yknT - - - ko:K06437 - ko00000 -
KMEHGPNO_01365 1.78e-120 rok - - K - - - Repressor of ComK
KMEHGPNO_01366 6.01e-104 ykuV - - CO - - - thiol-disulfide
KMEHGPNO_01367 9.78e-130 ykuU - - O - - - Alkyl hydroperoxide reductase
KMEHGPNO_01368 4.1e-181 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
KMEHGPNO_01369 7.23e-51 ykuS - - S - - - Belongs to the UPF0180 family
KMEHGPNO_01370 1.8e-272 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KMEHGPNO_01371 1.31e-125 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KMEHGPNO_01372 1.03e-101 fld - - C ko:K03839 - ko00000 Flavodoxin
KMEHGPNO_01373 3.51e-222 ykuO - - - - - - -
KMEHGPNO_01374 1.23e-110 - - - C ko:K03839 - ko00000 Flavodoxin domain
KMEHGPNO_01375 6.52e-216 ccpC - - K - - - Transcriptional regulator
KMEHGPNO_01376 5.15e-100 ykuL - - S - - - CBS domain
KMEHGPNO_01377 7.83e-38 ykzF - - S - - - Antirepressor AbbA
KMEHGPNO_01378 6.44e-122 - - - S ko:K09776 - ko00000 Ribonuclease H-like
KMEHGPNO_01379 5.16e-50 ykuJ - - S - - - protein conserved in bacteria
KMEHGPNO_01380 1.76e-298 ykuI - - T - - - Diguanylate phosphodiesterase
KMEHGPNO_01381 1.06e-181 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KMEHGPNO_01382 3.48e-212 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
KMEHGPNO_01383 5.84e-115 ykuD - - S - - - protein conserved in bacteria
KMEHGPNO_01384 2.55e-305 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
KMEHGPNO_01385 3.71e-110 ykyB - - S - - - YkyB-like protein
KMEHGPNO_01386 4.95e-216 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
KMEHGPNO_01387 1.05e-22 - - - - - - - -
KMEHGPNO_01388 1.4e-281 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
KMEHGPNO_01389 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KMEHGPNO_01390 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
KMEHGPNO_01391 3.62e-170 ykwD - - J - - - protein with SCP PR1 domains
KMEHGPNO_01392 1.68e-17 vgb - - H ko:K18235 - ko00000,ko01000,ko01504 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid
KMEHGPNO_01393 4.02e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
KMEHGPNO_01394 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
KMEHGPNO_01395 1.52e-162 ykwB - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KMEHGPNO_01396 2.49e-256 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
KMEHGPNO_01397 1.54e-51 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
KMEHGPNO_01398 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KMEHGPNO_01399 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
KMEHGPNO_01400 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KMEHGPNO_01401 6.87e-168 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
KMEHGPNO_01403 5.43e-229 ykvZ - - K - - - Transcriptional regulator
KMEHGPNO_01405 1.85e-262 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
KMEHGPNO_01406 3.99e-09 - - - - - - - -
KMEHGPNO_01407 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
KMEHGPNO_01408 5.79e-117 stoA - - CO - - - thiol-disulfide
KMEHGPNO_01409 6.46e-302 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KMEHGPNO_01410 4.32e-140 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
KMEHGPNO_01411 2.5e-39 - - - - - - - -
KMEHGPNO_01412 5.43e-35 ykvS - - S - - - protein conserved in bacteria
KMEHGPNO_01413 2.67e-62 ykvR - - S - - - Protein of unknown function (DUF3219)
KMEHGPNO_01414 1.44e-203 - - - G - - - Glycosyl hydrolases family 18
KMEHGPNO_01415 7.56e-48 - 3.5.1.104 - M ko:K22278 - ko00000,ko01000 LysM domain
KMEHGPNO_01416 2.47e-294 - - - M - - - Glycosyl transferases group 1
KMEHGPNO_01417 9.35e-173 ykvO - - IQ - - - Enoyl-(Acyl carrier protein) reductase
KMEHGPNO_01418 2.8e-81 ykvN - - K - - - Transcriptional regulator
KMEHGPNO_01419 2.36e-125 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KMEHGPNO_01420 1.45e-178 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
KMEHGPNO_01421 6.96e-105 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
KMEHGPNO_01422 6.42e-161 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KMEHGPNO_01423 6.76e-227 ykvI - - S - - - membrane
KMEHGPNO_01424 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
KMEHGPNO_01425 3.23e-178 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
KMEHGPNO_01426 4.91e-170 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
KMEHGPNO_01427 4.26e-98 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
KMEHGPNO_01428 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
KMEHGPNO_01429 5.84e-95 eag - - - - - - -
KMEHGPNO_01431 8.82e-68 - - - S - - - Protein of unknown function (DUF1232)
KMEHGPNO_01432 8.7e-123 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KMEHGPNO_01433 1.84e-146 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
KMEHGPNO_01434 7.2e-175 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
KMEHGPNO_01435 9.72e-295 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
KMEHGPNO_01436 4.81e-296 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
KMEHGPNO_01437 1.99e-193 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KMEHGPNO_01438 2.37e-291 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
KMEHGPNO_01439 1.62e-253 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KMEHGPNO_01441 2.76e-115 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KMEHGPNO_01442 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KMEHGPNO_01443 9.58e-244 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
KMEHGPNO_01444 1.77e-28 ykzE - - - - - - -
KMEHGPNO_01446 2.58e-310 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
KMEHGPNO_01447 3.97e-199 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
KMEHGPNO_01448 1.55e-159 ykrK - - S - - - Domain of unknown function (DUF1836)
KMEHGPNO_01449 1.4e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
KMEHGPNO_01450 2.83e-192 rsgI - - S - - - Anti-sigma factor N-terminus
KMEHGPNO_01451 1.8e-167 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KMEHGPNO_01452 4.63e-227 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
KMEHGPNO_01453 1.71e-143 ykoX - - S - - - membrane-associated protein
KMEHGPNO_01454 0.0 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
KMEHGPNO_01455 2.53e-204 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
KMEHGPNO_01456 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
KMEHGPNO_01457 9.49e-238 ykoT - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
KMEHGPNO_01458 0.0 ykoS - - - - - - -
KMEHGPNO_01459 1.77e-197 ykoQ - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
KMEHGPNO_01460 2.38e-127 ykoP - - G - - - polysaccharide deacetylase
KMEHGPNO_01461 1.58e-270 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
KMEHGPNO_01462 9.83e-106 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
KMEHGPNO_01463 3.04e-36 ykoL - - - - - - -
KMEHGPNO_01464 1.63e-25 - - - - - - - -
KMEHGPNO_01465 1.49e-70 tnrA - - K - - - transcriptional
KMEHGPNO_01466 9.86e-300 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
KMEHGPNO_01468 1.45e-08 - - - - - - - -
KMEHGPNO_01469 1.51e-110 ykoJ - - S - - - Peptidase propeptide and YPEB domain
KMEHGPNO_01470 3.74e-143 ykoI - - S - - - Peptidase propeptide and YPEB domain
KMEHGPNO_01471 2.46e-306 ykoH - - T - - - Histidine kinase
KMEHGPNO_01472 1.01e-157 ykoG - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KMEHGPNO_01473 9.94e-142 ykoF - - S - - - YKOF-related Family
KMEHGPNO_01474 5.67e-127 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
KMEHGPNO_01475 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KMEHGPNO_01476 3.8e-175 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
KMEHGPNO_01477 3.99e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KMEHGPNO_01478 4.27e-225 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
KMEHGPNO_01479 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KMEHGPNO_01480 1.15e-114 guaD 3.5.4.3 - FJ ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 COG0590 Cytosine adenosine deaminases
KMEHGPNO_01481 8.15e-94 ohrB - - O - - - Organic hydroperoxide resistance protein
KMEHGPNO_01482 5.78e-97 ohrR - - K - - - COG1846 Transcriptional regulators
KMEHGPNO_01483 3.98e-92 ohrA - - O - - - Organic hydroperoxide resistance protein
KMEHGPNO_01484 1.32e-288 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KMEHGPNO_01485 4.3e-255 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KMEHGPNO_01486 1.66e-217 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
KMEHGPNO_01487 1.36e-66 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
KMEHGPNO_01488 2.1e-71 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
KMEHGPNO_01489 1.2e-126 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KMEHGPNO_01490 2.61e-127 ykkA - - S - - - Protein of unknown function (DUF664)
KMEHGPNO_01491 3.95e-167 ykjA - - S - - - Protein of unknown function (DUF421)
KMEHGPNO_01492 2.11e-16 - - - - - - - -
KMEHGPNO_01493 4.4e-288 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KMEHGPNO_01494 1.55e-119 ykhA - - I - - - Acyl-CoA hydrolase
KMEHGPNO_01495 5.1e-205 ykgA - - E - - - Amidinotransferase
KMEHGPNO_01496 8.08e-261 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
KMEHGPNO_01497 8.44e-237 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KMEHGPNO_01498 5.11e-210 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
KMEHGPNO_01499 8.03e-256 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
KMEHGPNO_01500 1.37e-224 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
KMEHGPNO_01502 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
KMEHGPNO_01503 7.46e-234 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KMEHGPNO_01504 3.02e-224 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KMEHGPNO_01505 9.7e-204 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KMEHGPNO_01506 5.7e-196 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
KMEHGPNO_01507 3.89e-177 proG 1.5.1.2 - E ko:K00286,ko:K02239 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko02044 Pyrroline-5-carboxylate reductase
KMEHGPNO_01508 1.09e-280 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KMEHGPNO_01509 1.28e-228 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
KMEHGPNO_01510 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KMEHGPNO_01511 2.82e-233 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
KMEHGPNO_01512 2.57e-309 steT - - E ko:K03294 - ko00000 amino acid
KMEHGPNO_01513 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
KMEHGPNO_01514 1.54e-225 pit - - P ko:K03306 - ko00000 phosphate transporter
KMEHGPNO_01515 3.4e-175 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
KMEHGPNO_01516 1.78e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
KMEHGPNO_01518 3.73e-208 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
KMEHGPNO_01519 1.92e-51 xhlB - - S - - - SPP1 phage holin
KMEHGPNO_01520 2.21e-51 xhlA - - S - - - Haemolysin XhlA
KMEHGPNO_01521 8.05e-194 xepA - - - - - - -
KMEHGPNO_01522 6.35e-31 xkdX - - - - - - -
KMEHGPNO_01523 8.04e-70 xkdW - - S - - - XkdW protein
KMEHGPNO_01524 0.0 - - - - - - - -
KMEHGPNO_01525 6.29e-56 - - - - - - - -
KMEHGPNO_01526 3.23e-134 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
KMEHGPNO_01527 1.79e-243 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
KMEHGPNO_01528 7.71e-90 xkdS - - S - - - Protein of unknown function (DUF2634)
KMEHGPNO_01529 4.32e-53 xkdR - - S - - - Protein of unknown function (DUF2577)
KMEHGPNO_01530 2.7e-231 xkdQ - - G - - - NLP P60 protein
KMEHGPNO_01531 1.77e-158 xkdP - - S - - - Lysin motif
KMEHGPNO_01532 0.0 xkdO - - L - - - Transglycosylase SLT domain
KMEHGPNO_01533 3.34e-101 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
KMEHGPNO_01534 6.01e-99 xkdM - - S - - - Phage tail tube protein
KMEHGPNO_01535 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
KMEHGPNO_01536 2.87e-101 xkdJ - - - - - - -
KMEHGPNO_01537 2.38e-114 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
KMEHGPNO_01538 1.44e-83 yqbH - - S - - - Domain of unknown function (DUF3599)
KMEHGPNO_01539 1.63e-82 yqbG - - S - - - Protein of unknown function (DUF3199)
KMEHGPNO_01540 3.91e-217 xkdG - - S - - - Phage capsid family
KMEHGPNO_01541 9.88e-177 xkdF3 - - L - - - Putative phage serine protease XkdF
KMEHGPNO_01542 0.0 yqbA - - S - - - portal protein
KMEHGPNO_01543 0.0 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
KMEHGPNO_01544 5.58e-178 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
KMEHGPNO_01545 2.33e-109 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
KMEHGPNO_01549 7.48e-153 xkdC - - L - - - Bacterial dnaA protein
KMEHGPNO_01550 3.73e-203 xkdB - - K - - - sequence-specific DNA binding
KMEHGPNO_01552 2.01e-74 xre - - K - - - Helix-turn-helix XRE-family like proteins
KMEHGPNO_01553 1.53e-144 xkdA - - E - - - IrrE N-terminal-like domain
KMEHGPNO_01554 4.54e-204 yjqC - - P ko:K07217 - ko00000 Catalase
KMEHGPNO_01555 1.58e-138 yjqB - - S - - - Pfam:DUF867
KMEHGPNO_01556 1.3e-78 yjqA - - S - - - Bacterial PH domain
KMEHGPNO_01557 2.54e-216 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
KMEHGPNO_01558 1.79e-55 - - - S - - - YCII-related domain
KMEHGPNO_01560 7.06e-271 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
KMEHGPNO_01561 6.08e-314 VCP - - O - - - AAA domain (dynein-related subfamily)
KMEHGPNO_01562 1.1e-102 yjoA - - S - - - DinB family
KMEHGPNO_01563 4.56e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
KMEHGPNO_01564 0.0 uxaA 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
KMEHGPNO_01565 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
KMEHGPNO_01566 9.87e-238 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
KMEHGPNO_01567 1.86e-287 exuT - - G ko:K03535,ko:K08191 - ko00000,ko02000 Sugar (and other) transporter
KMEHGPNO_01568 2.23e-195 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
KMEHGPNO_01569 2.18e-270 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
KMEHGPNO_01570 3.76e-245 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
KMEHGPNO_01571 5.97e-241 allD 1.1.1.350 - C ko:K00073 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000 Belongs to the LDH2 MDH2 oxidoreductase family
KMEHGPNO_01572 1.69e-311 - - - G ko:K03292 - ko00000 symporter YjmB
KMEHGPNO_01573 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
KMEHGPNO_01574 2.15e-280 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
KMEHGPNO_01575 1.39e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
KMEHGPNO_01576 2.02e-117 yjlB - - S - - - Cupin domain
KMEHGPNO_01577 3.64e-224 yjlA - - EG - - - Putative multidrug resistance efflux transporter
KMEHGPNO_01578 2.79e-175 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
KMEHGPNO_01579 9.04e-156 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
KMEHGPNO_01580 2.49e-188 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
KMEHGPNO_01581 1.11e-41 - - - - - - - -
KMEHGPNO_01582 1.76e-279 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
KMEHGPNO_01583 1.52e-282 yjiB 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
KMEHGPNO_01585 4.15e-144 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
KMEHGPNO_01587 9.24e-122 yjgD - - S - - - Protein of unknown function (DUF1641)
KMEHGPNO_01588 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
KMEHGPNO_01589 4.96e-133 yjgB - - S - - - Domain of unknown function (DUF4309)
KMEHGPNO_01590 1.42e-213 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
KMEHGPNO_01591 1.13e-29 yjfB - - S - - - Putative motility protein
KMEHGPNO_01592 2.22e-108 - - - S - - - Protein of unknown function (DUF2690)
KMEHGPNO_01593 0.0 yjeA 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
KMEHGPNO_01595 6.19e-223 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
KMEHGPNO_01596 2.31e-69 yjdJ - - S - - - Domain of unknown function (DUF4306)
KMEHGPNO_01597 6.12e-40 - - - S - - - Domain of unknown function (DUF4177)
KMEHGPNO_01598 8.3e-105 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KMEHGPNO_01600 8.85e-118 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
KMEHGPNO_01601 9.24e-76 yjdF3 - - S - - - Protein of unknown function (DUF2992)
KMEHGPNO_01602 9.86e-238 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
KMEHGPNO_01603 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KMEHGPNO_01604 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
KMEHGPNO_01605 0.000759 - - - - - - - -
KMEHGPNO_01606 8.05e-180 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
KMEHGPNO_01607 1.27e-61 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
KMEHGPNO_01610 1.55e-33 - - - - - - - -
KMEHGPNO_01614 5.1e-108 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
KMEHGPNO_01615 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
KMEHGPNO_01616 1.3e-39 - - - S - - - Domain of unknown function (DUF4917)
KMEHGPNO_01618 2.85e-45 - - - S - - - peptidoglycan catabolic process
KMEHGPNO_01619 1.14e-20 - - - S - - - peptidoglycan catabolic process
KMEHGPNO_01621 2.59e-81 - - - - - - - -
KMEHGPNO_01624 6.59e-41 - - - - - - - -
KMEHGPNO_01625 1.33e-50 - - - - - - - -
KMEHGPNO_01628 1.74e-272 yjcL - - S - - - Protein of unknown function (DUF819)
KMEHGPNO_01629 2.13e-129 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
KMEHGPNO_01630 1.51e-279 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
KMEHGPNO_01631 1.98e-273 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
KMEHGPNO_01632 7.77e-177 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
KMEHGPNO_01633 1.2e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
KMEHGPNO_01634 7.75e-94 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KMEHGPNO_01635 6.31e-51 - - - - - - - -
KMEHGPNO_01636 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
KMEHGPNO_01637 5.39e-52 spoVIF - - S - - - Stage VI sporulation protein F
KMEHGPNO_01640 1.23e-75 yjcA - - S - - - Protein of unknown function (DUF1360)
KMEHGPNO_01641 4.12e-72 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
KMEHGPNO_01642 1.06e-34 cotW - - - ko:K06341 - ko00000 -
KMEHGPNO_01643 2.87e-94 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
KMEHGPNO_01644 3.12e-124 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
KMEHGPNO_01645 4.57e-108 cotZ - - S ko:K06344 - ko00000 Spore coat protein
KMEHGPNO_01646 1.71e-102 yjbX - - S - - - Spore coat protein
KMEHGPNO_01647 1.75e-182 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
KMEHGPNO_01648 8.38e-192 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
KMEHGPNO_01649 8.78e-238 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
KMEHGPNO_01650 6.78e-174 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
KMEHGPNO_01651 2.18e-41 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 thiamine diphosphate biosynthetic process
KMEHGPNO_01652 3.65e-274 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
KMEHGPNO_01653 6.65e-138 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
KMEHGPNO_01654 5.7e-177 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KMEHGPNO_01655 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
KMEHGPNO_01656 3.3e-180 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
KMEHGPNO_01657 1.49e-202 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
KMEHGPNO_01658 2.94e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KMEHGPNO_01659 5.06e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
KMEHGPNO_01660 5.35e-81 yjbL - - S - - - Belongs to the UPF0738 family
KMEHGPNO_01661 7.32e-130 yjbK - - S - - - protein conserved in bacteria
KMEHGPNO_01662 3.42e-127 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
KMEHGPNO_01663 8.58e-94 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
KMEHGPNO_01664 1.32e-218 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
KMEHGPNO_01665 2.68e-28 - - - - - - - -
KMEHGPNO_01666 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
KMEHGPNO_01667 2.33e-277 coiA - - S ko:K06198 - ko00000 Competence protein
KMEHGPNO_01668 6.89e-151 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
KMEHGPNO_01669 7.1e-144 yjbE - - P - - - Integral membrane protein TerC family
KMEHGPNO_01670 1.01e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KMEHGPNO_01671 8.88e-132 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KMEHGPNO_01672 6.76e-260 yjbB - - EGP - - - Major Facilitator Superfamily
KMEHGPNO_01673 1.27e-219 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KMEHGPNO_01674 3.22e-248 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KMEHGPNO_01675 7.55e-212 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KMEHGPNO_01676 4.19e-212 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KMEHGPNO_01677 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
KMEHGPNO_01678 6.15e-235 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
KMEHGPNO_01679 3.18e-190 yjbA - - S - - - Belongs to the UPF0736 family
KMEHGPNO_01680 1.03e-208 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KMEHGPNO_01681 6.73e-216 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KMEHGPNO_01682 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
KMEHGPNO_01683 1.99e-235 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KMEHGPNO_01684 6.15e-234 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KMEHGPNO_01685 9.1e-191 yjaZ - - O - - - Zn-dependent protease
KMEHGPNO_01686 3.06e-302 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KMEHGPNO_01687 1.61e-221 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KMEHGPNO_01688 4.43e-30 yjzB - - - - - - -
KMEHGPNO_01689 1.07e-35 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
KMEHGPNO_01690 3.7e-234 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
KMEHGPNO_01691 6.08e-131 yjaV - - - - - - -
KMEHGPNO_01692 1.4e-181 yjaU - - I - - - carboxylic ester hydrolase activity
KMEHGPNO_01693 2.17e-23 yjzD - - S - - - Protein of unknown function (DUF2929)
KMEHGPNO_01694 2.51e-39 yjzC - - S - - - YjzC-like protein
KMEHGPNO_01695 4.27e-225 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KMEHGPNO_01696 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
KMEHGPNO_01697 6.67e-262 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
KMEHGPNO_01698 2.8e-277 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
KMEHGPNO_01699 1.27e-175 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
KMEHGPNO_01700 2.48e-293 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KMEHGPNO_01701 1.18e-251 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KMEHGPNO_01702 3.24e-114 yitZ - - G - - - Major Facilitator Superfamily
KMEHGPNO_01703 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
KMEHGPNO_01704 1.74e-31 - - - S - - - Proteolipid membrane potential modulator
KMEHGPNO_01705 4.63e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
KMEHGPNO_01706 1.45e-184 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
KMEHGPNO_01707 5.29e-199 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
KMEHGPNO_01708 1.01e-25 - - - S - - - Protein of unknown function (DUF3813)
KMEHGPNO_01709 9.69e-94 ipi - - S - - - Intracellular proteinase inhibitor
KMEHGPNO_01710 2.29e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
KMEHGPNO_01711 2.51e-199 yitS - - S - - - protein conserved in bacteria
KMEHGPNO_01712 0.0 nprB 3.4.24.28 - E ko:K01400,ko:K08777 ko02024,map02024 ko00000,ko00001,ko01000,ko01002 Peptidase M4
KMEHGPNO_01713 4.59e-59 yitR - - S - - - Domain of unknown function (DUF3784)
KMEHGPNO_01714 5.02e-119 - - - - - - - -
KMEHGPNO_01715 2.08e-77 - - - K - - - Transcriptional regulator PadR-like family
KMEHGPNO_01716 3.29e-127 - - - S - - - Sporulation delaying protein SdpA
KMEHGPNO_01717 1.42e-218 - - - - - - - -
KMEHGPNO_01718 4.16e-122 - - - - - - - -
KMEHGPNO_01719 3.08e-201 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
KMEHGPNO_01720 1.75e-76 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
KMEHGPNO_01721 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
KMEHGPNO_01722 2.16e-93 - - - S - - - Acetyltransferase (GNAT) domain
KMEHGPNO_01723 1.5e-195 yitH - - K - - - Acetyltransferase (GNAT) domain
KMEHGPNO_01724 2.37e-290 yitG - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
KMEHGPNO_01725 2.14e-283 yitF 5.5.1.27 - M ko:K18983 ko00053,map00053 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
KMEHGPNO_01726 6.62e-140 yitE - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
KMEHGPNO_01727 7.15e-179 yitD 4.4.1.19 - S ko:K08097 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 synthase
KMEHGPNO_01728 5.62e-155 - 3.1.3.71 - H ko:K05979 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the ComB family
KMEHGPNO_01729 3.06e-181 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
KMEHGPNO_01730 3.1e-292 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
KMEHGPNO_01731 4.06e-145 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
KMEHGPNO_01732 1.07e-197 yisY 1.11.1.10 - I ko:K00433 - ko00000,ko01000 hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KMEHGPNO_01733 2.15e-96 yisX - - S - - - Pentapeptide repeats (9 copies)
KMEHGPNO_01734 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KMEHGPNO_01735 1.05e-137 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
KMEHGPNO_01736 9.94e-120 yisT - - S - - - DinB family
KMEHGPNO_01737 1.17e-245 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
KMEHGPNO_01738 5.26e-235 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
KMEHGPNO_01739 1.65e-206 yisR - - K - - - Transcriptional regulator
KMEHGPNO_01740 2.91e-310 yisQ - - V - - - Mate efflux family protein
KMEHGPNO_01741 2.1e-187 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
KMEHGPNO_01742 1.07e-114 yizA - - S - - - Damage-inducible protein DinB
KMEHGPNO_01743 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
KMEHGPNO_01744 8.67e-131 yisN - - S - - - Protein of unknown function (DUF2777)
KMEHGPNO_01745 0.0 wprA - - O ko:K13274 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
KMEHGPNO_01746 1.02e-74 yisL - - S - - - UPF0344 protein
KMEHGPNO_01747 2.66e-219 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
KMEHGPNO_01748 6.56e-223 cotH - - M ko:K06330 - ko00000 Spore Coat
KMEHGPNO_01749 1.52e-32 yisI - - S - - - Spo0E like sporulation regulatory protein
KMEHGPNO_01750 1.82e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
KMEHGPNO_01751 1.76e-47 gerPB - - S ko:K06300 - ko00000 cell differentiation
KMEHGPNO_01752 6.73e-92 gerPC - - S ko:K06301 - ko00000 Spore germination protein
KMEHGPNO_01753 1.49e-33 gerPD - - S ko:K06302 - ko00000 Spore germination protein
KMEHGPNO_01754 1.79e-82 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
KMEHGPNO_01755 3.3e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
KMEHGPNO_01756 3.71e-64 yisB - - V - - - COG1403 Restriction endonuclease
KMEHGPNO_01757 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
KMEHGPNO_01758 1.4e-280 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
KMEHGPNO_01759 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
KMEHGPNO_01760 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
KMEHGPNO_01761 9.3e-102 yhjR - - S - - - Rubrerythrin
KMEHGPNO_01762 4.17e-67 yhjQ - - C - - - COG1145 Ferredoxin
KMEHGPNO_01763 0.0 - - - S - - - Sugar transport-related sRNA regulator N-term
KMEHGPNO_01764 4.74e-268 - - - EGP - - - Transmembrane secretion effector
KMEHGPNO_01765 2.05e-258 yhjN - - S ko:K07120 - ko00000 membrane
KMEHGPNO_01766 5.09e-238 yhjM - - K - - - Transcriptional regulator
KMEHGPNO_01767 0.0 - 2.6.1.104 - E ko:K18653 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
KMEHGPNO_01768 5.31e-205 ntdB 3.1.3.24, 3.1.3.92 - S ko:K07024,ko:K18654 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose-6F-phosphate phosphohydrolase
KMEHGPNO_01769 3.27e-256 - 1.1.1.18, 1.1.1.361, 1.1.1.369 - S ko:K00010,ko:K18652 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
KMEHGPNO_01770 1.05e-270 glcP - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
KMEHGPNO_01773 8.09e-122 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
KMEHGPNO_01774 0.0 yhjG - - CH - - - FAD binding domain
KMEHGPNO_01775 3.09e-118 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
KMEHGPNO_01776 4.87e-141 yhjE - - S - - - SNARE associated Golgi protein
KMEHGPNO_01777 8.34e-78 yhjD - - - - - - -
KMEHGPNO_01778 1.61e-36 yhjC - - S - - - Protein of unknown function (DUF3311)
KMEHGPNO_01779 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KMEHGPNO_01780 4.64e-53 yhjA - - S - - - Excalibur calcium-binding domain
KMEHGPNO_01781 1.48e-215 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
KMEHGPNO_01782 9.07e-75 - - - FG - - - Domain of unknown function (DUF4269)
KMEHGPNO_01783 5.77e-210 - - - E - - - glucose-methanol-choline oxidoreductase
KMEHGPNO_01785 9.63e-36 - - - M - - - DegT/DnrJ/EryC1/StrS aminotransferase family
KMEHGPNO_01786 1.5e-50 - 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
KMEHGPNO_01787 9.74e-12 - - - - - - - -
KMEHGPNO_01788 6.02e-114 - - - - - - - -
KMEHGPNO_01789 2.41e-142 - - - V - - - HNH endonuclease
KMEHGPNO_01795 2.73e-34 - - - L - - - DNA helicase
KMEHGPNO_01796 6.7e-138 - 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 UvrD-like helicase C-terminal domain
KMEHGPNO_01799 4.27e-95 - - - S - - - Protein of unknown function (DUF3037)
KMEHGPNO_01800 2.27e-116 - - - - - - - -
KMEHGPNO_01801 1.24e-35 - - - - - - - -
KMEHGPNO_01802 5.43e-189 - - - L - - - Phage integrase family
KMEHGPNO_01803 1.29e-113 - - - L - - - Belongs to the 'phage' integrase family
KMEHGPNO_01804 7.07e-101 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
KMEHGPNO_01805 9.84e-45 yhzC - - S - - - IDEAL
KMEHGPNO_01806 2.24e-203 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KMEHGPNO_01807 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
KMEHGPNO_01808 1.85e-260 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
KMEHGPNO_01809 1.47e-118 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
KMEHGPNO_01810 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
KMEHGPNO_01811 8.96e-252 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
KMEHGPNO_01812 1.13e-139 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
KMEHGPNO_01813 1.32e-221 yhfQ - - M ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
KMEHGPNO_01814 1.33e-229 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
KMEHGPNO_01815 3.6e-101 - - - K - - - acetyltransferase
KMEHGPNO_01816 6.91e-260 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
KMEHGPNO_01817 6.5e-306 yhfN - - O - - - Peptidase M48
KMEHGPNO_01818 2.78e-85 yhfM - - - - - - -
KMEHGPNO_01819 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
KMEHGPNO_01820 8.67e-143 yhfK - - GM - - - NmrA-like family
KMEHGPNO_01821 4.06e-245 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
KMEHGPNO_01822 5.93e-183 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
KMEHGPNO_01823 4.77e-289 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KMEHGPNO_01824 1.53e-93 - - - S - - - ASCH
KMEHGPNO_01825 1.55e-252 yhfE - - G - - - peptidase M42
KMEHGPNO_01826 3.8e-177 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
KMEHGPNO_01827 1.25e-236 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KMEHGPNO_01828 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
KMEHGPNO_01829 5.79e-132 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
KMEHGPNO_01830 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KMEHGPNO_01831 2.69e-228 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
KMEHGPNO_01832 5.25e-259 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KMEHGPNO_01833 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
KMEHGPNO_01834 5.35e-118 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
KMEHGPNO_01835 7.73e-312 yhfA - - C - - - membrane
KMEHGPNO_01836 2.55e-290 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KMEHGPNO_01837 1.18e-160 ecsC - - S - - - EcsC protein family
KMEHGPNO_01838 1.27e-271 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
KMEHGPNO_01839 1.1e-175 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
KMEHGPNO_01840 3.5e-106 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
KMEHGPNO_01841 2.15e-261 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KMEHGPNO_01842 6.32e-104 trpP - - S - - - Tryptophan transporter TrpP
KMEHGPNO_01843 9.66e-30 - - - - - - - -
KMEHGPNO_01844 3.89e-54 yhaH - - S - - - YtxH-like protein
KMEHGPNO_01845 4.92e-148 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
KMEHGPNO_01846 8.48e-73 yhaI - - S - - - Protein of unknown function (DUF1878)
KMEHGPNO_01847 1.4e-116 yhaK - - S - - - Putative zincin peptidase
KMEHGPNO_01848 3.52e-167 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KMEHGPNO_01849 1.88e-39 yhaL - - S - - - Sporulation protein YhaL
KMEHGPNO_01850 5.22e-228 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
KMEHGPNO_01851 0.0 yhaN - - L - - - AAA domain
KMEHGPNO_01852 6.83e-294 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
KMEHGPNO_01853 5.99e-271 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
KMEHGPNO_01854 1.53e-212 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KMEHGPNO_01855 9.36e-36 - - - S - - - YhzD-like protein
KMEHGPNO_01856 8.38e-170 yhaR - - I - - - enoyl-CoA hydratase
KMEHGPNO_01858 6.51e-114 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
KMEHGPNO_01859 1.85e-267 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
KMEHGPNO_01860 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
KMEHGPNO_01861 8.7e-198 yhaX - - S - - - haloacid dehalogenase-like hydrolase
KMEHGPNO_01862 2.61e-261 yhaZ - - L - - - DNA alkylation repair enzyme
KMEHGPNO_01863 7.46e-72 yheA - - S - - - Belongs to the UPF0342 family
KMEHGPNO_01864 2.93e-259 yheB - - S - - - Belongs to the UPF0754 family
KMEHGPNO_01865 1.32e-273 yheC - - HJ - - - YheC/D like ATP-grasp
KMEHGPNO_01866 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
KMEHGPNO_01867 2.27e-49 yheE - - S - - - Family of unknown function (DUF5342)
KMEHGPNO_01868 1.25e-38 sspB - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
KMEHGPNO_01869 1.84e-140 yheG - - GM - - - NAD(P)H-binding
KMEHGPNO_01870 0.0 yheH - - V ko:K06147,ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
KMEHGPNO_01871 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
KMEHGPNO_01872 1.53e-108 nhaX - - T - - - Belongs to the universal stress protein A family
KMEHGPNO_01873 8.48e-302 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
KMEHGPNO_01874 3.16e-197 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
KMEHGPNO_01875 3.54e-194 nodB1 - - G - - - deacetylase
KMEHGPNO_01876 5.67e-178 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
KMEHGPNO_01877 9.73e-239 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
KMEHGPNO_01878 3.7e-09 yhdX - - S - - - Uncharacterized protein YhdX
KMEHGPNO_01879 1.5e-171 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
KMEHGPNO_01880 1.67e-86 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KMEHGPNO_01881 2.04e-65 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KMEHGPNO_01882 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
KMEHGPNO_01883 5.1e-284 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
KMEHGPNO_01884 3.44e-97 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
KMEHGPNO_01885 2.18e-304 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
KMEHGPNO_01886 3.9e-143 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
KMEHGPNO_01887 6.74e-244 yhdN - - C - - - Aldo keto reductase
KMEHGPNO_01888 3.24e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
KMEHGPNO_01889 6.13e-258 yhdL - - S - - - Sigma factor regulator N-terminal
KMEHGPNO_01890 4.27e-59 yhdK - - S - - - Sigma-M inhibitor protein
KMEHGPNO_01891 1.75e-100 - - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KMEHGPNO_01892 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KMEHGPNO_01893 1.01e-308 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
KMEHGPNO_01894 3.58e-316 yhdG - - E ko:K03294 - ko00000 amino acid
KMEHGPNO_01895 4.53e-205 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KMEHGPNO_01896 1.06e-260 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
KMEHGPNO_01897 4.93e-210 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
KMEHGPNO_01898 1.45e-203 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
KMEHGPNO_01899 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
KMEHGPNO_01900 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
KMEHGPNO_01901 2.5e-305 ygxB - - M - - - Conserved TM helix
KMEHGPNO_01902 5.58e-99 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
KMEHGPNO_01903 1.95e-272 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
KMEHGPNO_01904 1.02e-71 yhdC - - S - - - Protein of unknown function (DUF3889)
KMEHGPNO_01905 1.65e-51 yhdB - - S - - - YhdB-like protein
KMEHGPNO_01906 6.64e-116 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
KMEHGPNO_01907 4.47e-143 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KMEHGPNO_01908 1.04e-269 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
KMEHGPNO_01909 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
KMEHGPNO_01910 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KMEHGPNO_01911 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KMEHGPNO_01912 5.7e-196 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
KMEHGPNO_01913 6.25e-134 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KMEHGPNO_01914 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KMEHGPNO_01915 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KMEHGPNO_01916 2.5e-154 yhcW - - S ko:K07025 - ko00000 hydrolase
KMEHGPNO_01917 1.76e-90 yhcV - - S - - - COG0517 FOG CBS domain
KMEHGPNO_01918 1.74e-88 yhcU - - S - - - Family of unknown function (DUF5365)
KMEHGPNO_01919 4.78e-218 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
KMEHGPNO_01920 1.78e-134 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
KMEHGPNO_01921 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
KMEHGPNO_01922 2.29e-144 yhcQ - - M - - - Spore coat protein
KMEHGPNO_01923 4.62e-226 yhcP - - - - - - -
KMEHGPNO_01924 3.06e-101 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KMEHGPNO_01925 2.69e-62 yhcM - - - - - - -
KMEHGPNO_01926 3.22e-65 - - - K - - - Transcriptional regulator PadR-like family
KMEHGPNO_01927 1.19e-114 - - - S - - - Protein of unknown function (DUF2812)
KMEHGPNO_01928 2.62e-301 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KMEHGPNO_01929 2.76e-248 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
KMEHGPNO_01930 4.49e-194 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
KMEHGPNO_01931 1.91e-42 cspB - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
KMEHGPNO_01932 3.45e-212 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
KMEHGPNO_01933 3.59e-210 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KMEHGPNO_01934 3.24e-156 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KMEHGPNO_01935 1.67e-79 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
KMEHGPNO_01936 2.06e-69 - - - - - - - -
KMEHGPNO_01937 3.24e-58 yhcC - - - - - - -
KMEHGPNO_01938 4.87e-128 yhcB 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 Belongs to the WrbA family
KMEHGPNO_01939 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
KMEHGPNO_01940 2.67e-133 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
KMEHGPNO_01941 1.29e-101 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
KMEHGPNO_01942 1.21e-286 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
KMEHGPNO_01943 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
KMEHGPNO_01944 2.12e-105 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
KMEHGPNO_01945 1.32e-95 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
KMEHGPNO_01946 9.75e-143 yhbD - - K - - - Protein of unknown function (DUF4004)
KMEHGPNO_01947 6.53e-113 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KMEHGPNO_01948 1.95e-225 yhbB - - S - - - Putative amidase domain
KMEHGPNO_01949 2.42e-283 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KMEHGPNO_01950 6.43e-146 yhzB - - S - - - B3/4 domain
KMEHGPNO_01952 1.48e-39 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
KMEHGPNO_01953 3.13e-99 ygaO - - - - - - -
KMEHGPNO_01954 4.82e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KMEHGPNO_01956 2.68e-275 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
KMEHGPNO_01957 8.33e-190 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
KMEHGPNO_01958 8.45e-218 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
KMEHGPNO_01959 9.01e-179 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
KMEHGPNO_01960 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
KMEHGPNO_01962 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KMEHGPNO_01963 3.89e-137 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
KMEHGPNO_01964 1.58e-36 - - - - - - - -
KMEHGPNO_01965 5.24e-184 spo0M - - S ko:K06377 - ko00000 COG4326 Sporulation control protein
KMEHGPNO_01982 2.53e-97 nucB - - M - - - Deoxyribonuclease NucA/NucB
KMEHGPNO_01983 5.21e-168 - - - - - - - -
KMEHGPNO_01984 3.62e-215 yqeC 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconate dehydrogenase
KMEHGPNO_01985 6.59e-135 yqeD - - S - - - SNARE associated Golgi protein
KMEHGPNO_01986 1.24e-178 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
KMEHGPNO_01987 2.24e-182 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
KMEHGPNO_01989 2.17e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
KMEHGPNO_01990 4.78e-273 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
KMEHGPNO_01991 8.1e-199 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KMEHGPNO_01992 8.95e-61 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
KMEHGPNO_01993 2.47e-141 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KMEHGPNO_01994 3.95e-132 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
KMEHGPNO_01995 1.39e-81 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KMEHGPNO_01996 5.44e-176 yqeM - - Q - - - Methyltransferase
KMEHGPNO_01997 1.82e-187 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KMEHGPNO_01998 3.84e-135 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
KMEHGPNO_01999 3.25e-137 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
KMEHGPNO_02000 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
KMEHGPNO_02001 2.36e-22 - - - S - - - YqzM-like protein
KMEHGPNO_02002 9.55e-243 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
KMEHGPNO_02003 4e-49 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
KMEHGPNO_02004 3.42e-258 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
KMEHGPNO_02005 2.73e-283 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
KMEHGPNO_02006 1.17e-68 yqxA - - S - - - Protein of unknown function (DUF3679)
KMEHGPNO_02007 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KMEHGPNO_02008 1.13e-273 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
KMEHGPNO_02009 1.65e-241 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KMEHGPNO_02010 4.36e-116 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KMEHGPNO_02011 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
KMEHGPNO_02012 3.41e-257 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KMEHGPNO_02013 1.33e-224 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
KMEHGPNO_02014 1.14e-177 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KMEHGPNO_02015 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
KMEHGPNO_02016 1.64e-200 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
KMEHGPNO_02017 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
KMEHGPNO_02018 2.25e-90 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
KMEHGPNO_02019 2.18e-289 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
KMEHGPNO_02020 4.35e-192 yqfA - - S - - - UPF0365 protein
KMEHGPNO_02021 5.2e-78 yqfB - - - - - - -
KMEHGPNO_02022 2.07e-60 yqfC - - S - - - sporulation protein YqfC
KMEHGPNO_02023 1.04e-242 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
KMEHGPNO_02024 4.99e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
KMEHGPNO_02026 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
KMEHGPNO_02027 8.68e-106 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KMEHGPNO_02028 4.75e-80 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
KMEHGPNO_02029 6.71e-93 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
KMEHGPNO_02030 9.98e-215 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KMEHGPNO_02031 5.29e-27 - - - S - - - YqzL-like protein
KMEHGPNO_02032 2.14e-186 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
KMEHGPNO_02033 2.12e-222 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
KMEHGPNO_02034 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
KMEHGPNO_02035 3.29e-144 ccpN - - K - - - CBS domain
KMEHGPNO_02036 6.38e-191 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
KMEHGPNO_02037 6.03e-114 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
KMEHGPNO_02038 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KMEHGPNO_02039 2.79e-254 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KMEHGPNO_02040 1.61e-81 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
KMEHGPNO_02041 8.05e-149 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
KMEHGPNO_02042 1.26e-267 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KMEHGPNO_02043 1.75e-226 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KMEHGPNO_02044 3.36e-49 yqfQ - - S - - - YqfQ-like protein
KMEHGPNO_02045 1.55e-310 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KMEHGPNO_02046 4.23e-214 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KMEHGPNO_02047 3.01e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
KMEHGPNO_02048 3.83e-199 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
KMEHGPNO_02049 4.98e-106 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
KMEHGPNO_02050 4.78e-141 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
KMEHGPNO_02051 2.04e-81 yqfX - - S - - - membrane
KMEHGPNO_02052 5.22e-257 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KMEHGPNO_02053 1.35e-61 yqfZ - - M ko:K06417 - ko00000 LysM domain
KMEHGPNO_02054 3.2e-167 yqgB - - S - - - Protein of unknown function (DUF1189)
KMEHGPNO_02055 8.25e-101 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
KMEHGPNO_02056 1.59e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
KMEHGPNO_02057 3.96e-293 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
KMEHGPNO_02058 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
KMEHGPNO_02059 1.06e-204 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
KMEHGPNO_02060 7.11e-203 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
KMEHGPNO_02061 8.71e-201 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
KMEHGPNO_02062 9.78e-190 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KMEHGPNO_02063 1.29e-185 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KMEHGPNO_02064 1.09e-93 yqzC - - S - - - YceG-like family
KMEHGPNO_02065 3.42e-68 yqzD - - - - - - -
KMEHGPNO_02067 1.6e-247 yqgM 2.4.1.250 - M ko:K15521 - ko00000,ko01000 Glycosyl transferases group 1
KMEHGPNO_02068 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
KMEHGPNO_02069 3.25e-136 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KMEHGPNO_02070 3.38e-14 yqgO - - - - - - -
KMEHGPNO_02071 8.21e-302 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
KMEHGPNO_02072 9.15e-45 yqgQ - - S - - - Protein conserved in bacteria
KMEHGPNO_02073 3.28e-230 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
KMEHGPNO_02074 0.0 yqgS 2.7.8.20 - M ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
KMEHGPNO_02075 4.14e-281 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
KMEHGPNO_02076 1.81e-254 yqgU - - - - - - -
KMEHGPNO_02077 7.34e-66 yqgV - - S - - - Thiamine-binding protein
KMEHGPNO_02078 1.91e-31 yqgW - - S - - - Protein of unknown function (DUF2759)
KMEHGPNO_02079 1.3e-156 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
KMEHGPNO_02080 1.46e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
KMEHGPNO_02081 7.79e-85 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
KMEHGPNO_02083 7.35e-187 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KMEHGPNO_02084 1.16e-304 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
KMEHGPNO_02085 1.51e-233 yqxL - - P - - - Mg2 transporter protein
KMEHGPNO_02086 4.03e-05 - - - S - - - CBS domain
KMEHGPNO_02087 9.05e-257 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KMEHGPNO_02088 1.76e-218 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
KMEHGPNO_02089 4.39e-62 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
KMEHGPNO_02090 9.32e-92 gspH - - NU ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02035,ko02044 protein transport across the cell outer membrane
KMEHGPNO_02091 1.77e-78 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
KMEHGPNO_02092 2.38e-45 comGF - - U ko:K02246,ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
KMEHGPNO_02093 3.78e-57 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
KMEHGPNO_02094 4.9e-37 yqzE - - S - - - YqzE-like protein
KMEHGPNO_02095 6.36e-71 yqzG - - S - - - Protein of unknown function (DUF3889)
KMEHGPNO_02096 5.63e-156 yqxM - - - ko:K19433 - ko00000 -
KMEHGPNO_02097 1.74e-96 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
KMEHGPNO_02098 3.14e-182 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
KMEHGPNO_02099 3.69e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
KMEHGPNO_02100 1.39e-33 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
KMEHGPNO_02101 1.84e-196 yqhG - - S - - - Bacterial protein YqhG of unknown function
KMEHGPNO_02102 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
KMEHGPNO_02103 1.91e-261 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
KMEHGPNO_02104 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KMEHGPNO_02105 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KMEHGPNO_02106 7.5e-83 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
KMEHGPNO_02107 3.73e-203 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
KMEHGPNO_02108 1.97e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
KMEHGPNO_02109 7e-210 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
KMEHGPNO_02110 5.18e-81 yqhP - - - - - - -
KMEHGPNO_02111 2.98e-220 yqhQ - - S - - - Protein of unknown function (DUF1385)
KMEHGPNO_02112 8.02e-121 yqhR - - S - - - Conserved membrane protein YqhR
KMEHGPNO_02113 1.17e-101 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
KMEHGPNO_02114 2.99e-249 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
KMEHGPNO_02115 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KMEHGPNO_02116 6.96e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
KMEHGPNO_02117 8.22e-217 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
KMEHGPNO_02118 3.29e-110 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
KMEHGPNO_02119 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
KMEHGPNO_02120 1.93e-77 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
KMEHGPNO_02121 7.65e-257 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
KMEHGPNO_02122 1.28e-131 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
KMEHGPNO_02123 1.08e-148 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
KMEHGPNO_02124 9.92e-135 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
KMEHGPNO_02125 3.21e-93 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KMEHGPNO_02126 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
KMEHGPNO_02127 1.65e-88 yqhY - - S - - - protein conserved in bacteria
KMEHGPNO_02128 4.8e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KMEHGPNO_02129 4.34e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KMEHGPNO_02130 1.02e-311 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KMEHGPNO_02131 1.09e-51 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KMEHGPNO_02132 4.2e-209 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
KMEHGPNO_02133 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KMEHGPNO_02134 1.77e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
KMEHGPNO_02135 8.85e-102 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
KMEHGPNO_02136 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
KMEHGPNO_02137 2.96e-302 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
KMEHGPNO_02138 1.89e-186 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
KMEHGPNO_02140 5.68e-273 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
KMEHGPNO_02141 4.74e-37 - - - - - - - -
KMEHGPNO_02142 9.4e-138 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
KMEHGPNO_02143 1.96e-167 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
KMEHGPNO_02144 3.16e-278 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
KMEHGPNO_02145 9.4e-197 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
KMEHGPNO_02146 1.73e-268 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
KMEHGPNO_02147 2.07e-261 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
KMEHGPNO_02148 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
KMEHGPNO_02149 8.08e-205 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KMEHGPNO_02150 4.47e-46 yqzF - - S - - - Protein of unknown function (DUF2627)
KMEHGPNO_02151 0.0 bkdR - - KT - - - Transcriptional regulator
KMEHGPNO_02152 3.52e-198 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
KMEHGPNO_02153 1.92e-262 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
KMEHGPNO_02154 1.38e-254 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
KMEHGPNO_02155 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KMEHGPNO_02156 1.92e-238 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KMEHGPNO_02157 6.92e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KMEHGPNO_02158 7.95e-290 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KMEHGPNO_02159 2.6e-194 - - - K ko:K19575 - ko00000,ko00002,ko03000 helix_turn_helix, mercury resistance
KMEHGPNO_02160 3.09e-267 norA - - EGP ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
KMEHGPNO_02161 2.45e-213 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KMEHGPNO_02162 7.65e-101 yqiW - - S - - - Belongs to the UPF0403 family
KMEHGPNO_02163 1.18e-174 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
KMEHGPNO_02164 8.94e-143 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
KMEHGPNO_02165 1.49e-165 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
KMEHGPNO_02166 1.73e-221 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
KMEHGPNO_02167 3.43e-128 yqjB - - S - - - protein conserved in bacteria
KMEHGPNO_02169 5.45e-94 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
KMEHGPNO_02170 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
KMEHGPNO_02171 5.26e-259 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
KMEHGPNO_02172 1.57e-177 yqjF - - S ko:K09166 - ko00000 Uncharacterized conserved protein (COG2071)
KMEHGPNO_02173 1.37e-183 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KMEHGPNO_02174 3.57e-32 yqzJ - - - - - - -
KMEHGPNO_02175 7.8e-301 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KMEHGPNO_02176 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KMEHGPNO_02177 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KMEHGPNO_02178 1.8e-220 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KMEHGPNO_02179 8.59e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
KMEHGPNO_02180 3.17e-187 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KMEHGPNO_02181 1.21e-245 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
KMEHGPNO_02182 0.0 rocB - - E - - - arginine degradation protein
KMEHGPNO_02183 3.25e-188 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KMEHGPNO_02184 1.56e-227 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
KMEHGPNO_02185 6.89e-185 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
KMEHGPNO_02186 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
KMEHGPNO_02187 6.6e-229 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
KMEHGPNO_02188 1.28e-93 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KMEHGPNO_02190 3.24e-286 yqjV - - G - - - Major Facilitator Superfamily
KMEHGPNO_02192 4.03e-304 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KMEHGPNO_02193 2.66e-65 yqiX - - S - - - YolD-like protein
KMEHGPNO_02194 1.5e-110 yqjY - - K ko:K06977 - ko00000 acetyltransferase
KMEHGPNO_02195 6.44e-78 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
KMEHGPNO_02196 5.14e-245 yqkA - - K - - - GrpB protein
KMEHGPNO_02197 1.25e-72 yqkB - - S - - - Belongs to the HesB IscA family
KMEHGPNO_02198 1.12e-53 yqkC - - S - - - Protein of unknown function (DUF2552)
KMEHGPNO_02199 9.3e-220 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
KMEHGPNO_02200 6.61e-26 yqkE - - S - - - Protein of unknown function (DUF3886)
KMEHGPNO_02201 1.04e-214 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
KMEHGPNO_02202 8.21e-10 - - - S - - - Protein of unknown function (DUF3936)
KMEHGPNO_02203 4.07e-120 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
KMEHGPNO_02204 9.39e-277 yqxK - - L - - - DNA helicase
KMEHGPNO_02205 3.18e-77 ansR - - K - - - Transcriptional regulator
KMEHGPNO_02206 1.77e-238 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
KMEHGPNO_02207 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
KMEHGPNO_02208 0.0 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
KMEHGPNO_02209 3.95e-309 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
KMEHGPNO_02210 7.27e-42 yqkK - - - - - - -
KMEHGPNO_02211 1.96e-139 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
KMEHGPNO_02212 2.26e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
KMEHGPNO_02213 2.73e-50 - - - S - - - Protein of unknown function (DUF4227)
KMEHGPNO_02214 4.57e-213 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
KMEHGPNO_02215 6.8e-294 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
KMEHGPNO_02216 1.39e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KMEHGPNO_02217 9.65e-271 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
KMEHGPNO_02218 3e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
KMEHGPNO_02219 1.37e-99 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
KMEHGPNO_02220 1.18e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KMEHGPNO_02221 1.15e-143 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
KMEHGPNO_02222 5.43e-90 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
KMEHGPNO_02223 2.74e-101 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
KMEHGPNO_02224 6.02e-246 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
KMEHGPNO_02225 2.15e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
KMEHGPNO_02226 1.85e-143 - - - S ko:K06407 - ko00000 stage V sporulation protein
KMEHGPNO_02227 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
KMEHGPNO_02228 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KMEHGPNO_02229 8.93e-192 ypuA - - S - - - Secreted protein
KMEHGPNO_02230 1.23e-105 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KMEHGPNO_02236 4.28e-42 - - - S - - - Pfam Transposase IS66
KMEHGPNO_02237 1.5e-33 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KMEHGPNO_02239 1.02e-42 ypzJ - - S ko:K07069 - ko00000 nucleic-acid-binding protein containing a Zn-ribbon domain
KMEHGPNO_02240 1.18e-132 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
KMEHGPNO_02241 5.98e-72 ypuD - - - - - - -
KMEHGPNO_02242 2.07e-260 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KMEHGPNO_02243 2.5e-147 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
KMEHGPNO_02244 5.16e-291 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KMEHGPNO_02245 8.41e-107 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
KMEHGPNO_02246 1.12e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KMEHGPNO_02247 1.19e-118 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
KMEHGPNO_02248 3.82e-167 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KMEHGPNO_02249 9.54e-134 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KMEHGPNO_02250 2.92e-126 ypuI - - S - - - Protein of unknown function (DUF3907)
KMEHGPNO_02251 9.67e-272 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
KMEHGPNO_02252 7.57e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
KMEHGPNO_02253 8.62e-114 spmB - - S ko:K06374 - ko00000 Spore maturation protein
KMEHGPNO_02254 4.45e-169 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
KMEHGPNO_02255 1.5e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
KMEHGPNO_02256 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
KMEHGPNO_02257 9.03e-277 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
KMEHGPNO_02258 6.88e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KMEHGPNO_02259 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KMEHGPNO_02260 1.08e-133 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
KMEHGPNO_02261 4.8e-237 rsiX - - - - - - -
KMEHGPNO_02262 6.53e-172 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
KMEHGPNO_02263 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KMEHGPNO_02264 1.78e-121 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KMEHGPNO_02265 8.35e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
KMEHGPNO_02266 1.05e-253 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
KMEHGPNO_02267 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
KMEHGPNO_02268 3.55e-128 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
KMEHGPNO_02269 2.62e-137 ypbE - - M - - - Lysin motif
KMEHGPNO_02270 8.23e-106 ypbF - - S - - - Protein of unknown function (DUF2663)
KMEHGPNO_02271 3.73e-104 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
KMEHGPNO_02272 1.32e-65 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
KMEHGPNO_02273 5.56e-136 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
KMEHGPNO_02274 1.42e-308 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
KMEHGPNO_02275 4.25e-223 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
KMEHGPNO_02276 7.18e-153 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
KMEHGPNO_02277 6.93e-208 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
KMEHGPNO_02278 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
KMEHGPNO_02279 1.04e-140 ypfA - - M - - - Flagellar protein YcgR
KMEHGPNO_02280 1.39e-29 - - - S - - - Family of unknown function (DUF5359)
KMEHGPNO_02281 3.91e-144 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
KMEHGPNO_02282 7.8e-262 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
KMEHGPNO_02283 9.39e-235 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KMEHGPNO_02284 1.13e-11 - - - S - - - YpzI-like protein
KMEHGPNO_02285 2.73e-134 yphA - - - - - - -
KMEHGPNO_02286 4.35e-207 yphB - - S ko:K05739 - ko00000 YIEGIA protein
KMEHGPNO_02287 5.91e-38 ypzH - - - - - - -
KMEHGPNO_02288 1.72e-315 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
KMEHGPNO_02289 2.01e-243 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
KMEHGPNO_02290 7.09e-27 yphE - - S - - - Protein of unknown function (DUF2768)
KMEHGPNO_02291 4.31e-176 yphF - - - - - - -
KMEHGPNO_02292 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KMEHGPNO_02293 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KMEHGPNO_02294 4.41e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
KMEHGPNO_02295 5.13e-46 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
KMEHGPNO_02296 8.72e-178 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
KMEHGPNO_02297 1.34e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
KMEHGPNO_02298 4.09e-249 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
KMEHGPNO_02299 2.17e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
KMEHGPNO_02300 5.03e-181 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
KMEHGPNO_02301 1.44e-277 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KMEHGPNO_02302 1.35e-261 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KMEHGPNO_02303 9.82e-84 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
KMEHGPNO_02304 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KMEHGPNO_02305 5e-229 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KMEHGPNO_02306 4.18e-145 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
KMEHGPNO_02307 1.91e-151 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
KMEHGPNO_02308 1.48e-291 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KMEHGPNO_02309 3.66e-184 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
KMEHGPNO_02310 1.24e-256 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KMEHGPNO_02311 1.21e-264 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
KMEHGPNO_02312 4.03e-301 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KMEHGPNO_02313 3.56e-297 ypiA - - S - - - COG0457 FOG TPR repeat
KMEHGPNO_02314 1.83e-129 ypiB - - S - - - Belongs to the UPF0302 family
KMEHGPNO_02315 5.55e-100 ypiF - - S - - - Protein of unknown function (DUF2487)
KMEHGPNO_02316 3.35e-126 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
KMEHGPNO_02317 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
KMEHGPNO_02318 5.71e-191 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
KMEHGPNO_02319 6.63e-125 ypjA - - S - - - membrane
KMEHGPNO_02320 1.38e-182 ypjB - - S - - - sporulation protein
KMEHGPNO_02321 3.7e-200 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
KMEHGPNO_02322 1.01e-73 ypjD - - S - - - Nucleotide pyrophosphohydrolase
KMEHGPNO_02323 2.4e-189 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KMEHGPNO_02324 1.03e-92 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
KMEHGPNO_02325 1.89e-166 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
KMEHGPNO_02326 4.94e-267 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
KMEHGPNO_02327 5.87e-276 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KMEHGPNO_02328 6.91e-234 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KMEHGPNO_02329 1.98e-193 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
KMEHGPNO_02330 5.47e-200 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KMEHGPNO_02331 4.16e-85 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
KMEHGPNO_02332 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
KMEHGPNO_02333 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
KMEHGPNO_02334 2.66e-102 ypmB - - S - - - protein conserved in bacteria
KMEHGPNO_02335 2.53e-284 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
KMEHGPNO_02336 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
KMEHGPNO_02337 1.56e-163 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
KMEHGPNO_02338 3.57e-158 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KMEHGPNO_02339 1.67e-120 ypoC - - - - - - -
KMEHGPNO_02340 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
KMEHGPNO_02341 3.2e-150 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KMEHGPNO_02342 2.94e-237 yppC - - S - - - Protein of unknown function (DUF2515)
KMEHGPNO_02345 7.9e-10 yppE - - S - - - Bacterial domain of unknown function (DUF1798)
KMEHGPNO_02346 9.21e-11 - - - S - - - YppF-like protein
KMEHGPNO_02347 1.45e-66 yppG - - S - - - YppG-like protein
KMEHGPNO_02348 2.06e-93 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
KMEHGPNO_02349 2.13e-109 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
KMEHGPNO_02350 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
KMEHGPNO_02351 5.68e-298 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
KMEHGPNO_02352 2.4e-128 ypsA - - S - - - Belongs to the UPF0398 family
KMEHGPNO_02353 2.97e-60 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KMEHGPNO_02354 1.16e-285 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
KMEHGPNO_02356 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
KMEHGPNO_02357 4.63e-176 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KMEHGPNO_02358 2.96e-203 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
KMEHGPNO_02359 7.8e-238 kdgR - - K ko:K02525 - ko00000,ko03000 transcriptional
KMEHGPNO_02360 1.15e-236 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
KMEHGPNO_02361 1.03e-132 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
KMEHGPNO_02362 4.09e-224 kdgT - - P ko:K02526 - ko00000,ko02000 The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
KMEHGPNO_02363 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KMEHGPNO_02364 5.51e-127 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KMEHGPNO_02365 8.61e-292 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
KMEHGPNO_02366 2.63e-265 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
KMEHGPNO_02367 3.33e-113 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
KMEHGPNO_02369 0.0 ypbR - - S - - - Dynamin family
KMEHGPNO_02370 4.07e-52 ypbS - - S - - - Protein of unknown function (DUF2533)
KMEHGPNO_02371 1.08e-11 - - - - - - - -
KMEHGPNO_02372 2.26e-213 ypcP - - L - - - 5'3' exonuclease
KMEHGPNO_02373 5.23e-05 - - - - ko:K06429 - ko00000 -
KMEHGPNO_02374 7.64e-88 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
KMEHGPNO_02375 3.27e-136 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KMEHGPNO_02376 2.13e-158 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
KMEHGPNO_02377 1.54e-37 ypeQ - - S - - - Zinc-finger
KMEHGPNO_02378 1.05e-40 - - - S - - - Protein of unknown function (DUF2564)
KMEHGPNO_02379 1.17e-22 degR - - - - - - -
KMEHGPNO_02380 5.12e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
KMEHGPNO_02381 3.67e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
KMEHGPNO_02382 2.04e-223 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KMEHGPNO_02383 1.43e-110 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
KMEHGPNO_02384 2.07e-141 yagB - - S ko:K06950 - ko00000 phosphohydrolase
KMEHGPNO_02385 2.32e-203 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
KMEHGPNO_02386 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
KMEHGPNO_02387 9.69e-99 yphP - - S - - - Belongs to the UPF0403 family
KMEHGPNO_02388 4.85e-184 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
KMEHGPNO_02389 3.47e-148 ypjP - - S - - - YpjP-like protein
KMEHGPNO_02390 8.91e-121 ltrC 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
KMEHGPNO_02391 3.9e-121 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KMEHGPNO_02392 9.49e-143 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
KMEHGPNO_02393 8.03e-143 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
KMEHGPNO_02394 5.47e-234 yplP - - K - - - Transcriptional regulator
KMEHGPNO_02395 1.04e-309 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KMEHGPNO_02396 2.12e-53 ypmP - - S - - - Protein of unknown function (DUF2535)
KMEHGPNO_02397 2.27e-139 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
KMEHGPNO_02398 5.21e-178 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
KMEHGPNO_02399 3.23e-127 ypmS - - S - - - protein conserved in bacteria
KMEHGPNO_02400 8.69e-40 ypmT - - S - - - Uncharacterized ympT
KMEHGPNO_02401 9.99e-290 mepA - - V - - - MATE efflux family protein
KMEHGPNO_02402 4.14e-94 ypoP - - K - - - transcriptional
KMEHGPNO_02403 9.83e-133 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KMEHGPNO_02404 7.13e-103 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
KMEHGPNO_02405 1.66e-157 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
KMEHGPNO_02406 2.31e-279 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
KMEHGPNO_02407 5.2e-225 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
KMEHGPNO_02408 3.1e-83 cgeA - - - ko:K06319 - ko00000 -
KMEHGPNO_02409 1.76e-58 cgeC - - - ko:K06321 - ko00000 -
KMEHGPNO_02410 0.0 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
KMEHGPNO_02411 2.31e-183 yiiD - - K ko:K06323 - ko00000 acetyltransferase
KMEHGPNO_02413 3.74e-316 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KMEHGPNO_02414 1.97e-160 atoD 2.8.3.8, 2.8.3.9 - I ko:K01034 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KMEHGPNO_02415 3.85e-152 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
KMEHGPNO_02416 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
KMEHGPNO_02417 2.51e-195 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
KMEHGPNO_02418 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
KMEHGPNO_02419 9.87e-63 yokU - - S - - - YokU-like protein, putative antitoxin
KMEHGPNO_02420 7.3e-50 yozE - - S - - - Belongs to the UPF0346 family
KMEHGPNO_02421 7.44e-159 yodN - - - - - - -
KMEHGPNO_02423 5.18e-34 yozD - - S - - - YozD-like protein
KMEHGPNO_02424 5.48e-136 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
KMEHGPNO_02425 1.17e-71 yodL - - S - - - YodL-like
KMEHGPNO_02426 2.08e-12 - - - - - - - -
KMEHGPNO_02427 1.68e-163 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
KMEHGPNO_02428 1.33e-189 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
KMEHGPNO_02429 4.86e-41 yodI - - - - - - -
KMEHGPNO_02430 1.24e-165 yodH - - Q - - - Methyltransferase
KMEHGPNO_02431 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
KMEHGPNO_02432 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KMEHGPNO_02433 2.36e-38 - - - S - - - Protein of unknown function (DUF3311)
KMEHGPNO_02434 1.68e-223 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
KMEHGPNO_02435 3.76e-146 yahD - - S ko:K06999 - ko00000 Carboxylesterase
KMEHGPNO_02436 1.11e-139 yodC - - C - - - nitroreductase
KMEHGPNO_02437 2.63e-73 yodB - - K - - - transcriptional
KMEHGPNO_02438 3.97e-84 iolK - - S - - - tautomerase
KMEHGPNO_02439 5.59e-291 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
KMEHGPNO_02440 1.95e-14 - - - - - - - -
KMEHGPNO_02441 2.88e-103 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
KMEHGPNO_02442 1.92e-206 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
KMEHGPNO_02443 5.31e-58 - - - - - - - -
KMEHGPNO_02444 2.32e-79 yojF - - S - - - Protein of unknown function (DUF1806)
KMEHGPNO_02445 1.06e-160 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
KMEHGPNO_02446 2.05e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KMEHGPNO_02447 2.06e-313 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
KMEHGPNO_02449 3.54e-140 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KMEHGPNO_02450 5.62e-294 yojK - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
KMEHGPNO_02451 1.07e-266 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
KMEHGPNO_02452 1.26e-142 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KMEHGPNO_02453 4.45e-206 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
KMEHGPNO_02454 0.0 yojO - - P - - - Von Willebrand factor
KMEHGPNO_02455 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
KMEHGPNO_02456 3.16e-265 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
KMEHGPNO_02457 4.5e-212 yocS - - S ko:K03453 - ko00000 -transporter
KMEHGPNO_02458 4.35e-300 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
KMEHGPNO_02459 1.12e-210 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
KMEHGPNO_02460 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
KMEHGPNO_02461 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
KMEHGPNO_02462 1.91e-42 yozC - - - - - - -
KMEHGPNO_02463 2.17e-74 yozO - - S - - - Bacterial PH domain
KMEHGPNO_02464 1.83e-49 yocN - - - - - - -
KMEHGPNO_02465 2.94e-55 yozN - - - - - - -
KMEHGPNO_02466 5.43e-114 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
KMEHGPNO_02467 3.93e-41 - - - - - - - -
KMEHGPNO_02468 4.29e-70 yocL - - - - - - -
KMEHGPNO_02469 2.87e-107 yocK - - T - - - general stress protein
KMEHGPNO_02470 4.18e-147 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KMEHGPNO_02471 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
KMEHGPNO_02472 3.92e-173 yocH - - M - - - COG1388 FOG LysM repeat
KMEHGPNO_02473 4.71e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KMEHGPNO_02474 4.09e-251 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KMEHGPNO_02475 5.67e-258 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
KMEHGPNO_02476 3.19e-239 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
KMEHGPNO_02477 1.08e-121 yocC - - - - - - -
KMEHGPNO_02478 8.69e-184 - - - - - - - -
KMEHGPNO_02479 3.97e-119 yozB - - S ko:K08976 - ko00000 membrane
KMEHGPNO_02480 9.39e-157 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
KMEHGPNO_02481 8.12e-69 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
KMEHGPNO_02482 2.37e-117 yobW - - - - - - -
KMEHGPNO_02483 8.26e-222 yobV - - K - - - WYL domain
KMEHGPNO_02484 8.64e-112 - - - K - - - Bacterial transcription activator, effector binding domain
KMEHGPNO_02485 1.34e-169 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
KMEHGPNO_02486 3.09e-127 yobS - - K - - - Transcriptional regulator
KMEHGPNO_02487 3.99e-178 - - - J - - - FR47-like protein
KMEHGPNO_02488 1.18e-171 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
KMEHGPNO_02489 9e-72 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
KMEHGPNO_02490 0.0 yobO - - M - - - Pectate lyase superfamily protein
KMEHGPNO_02491 0.0 iaaM 1.4.3.4 - E ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 ko00000,ko00001,ko00002,ko01000 COG1231 Monoamine oxidase
KMEHGPNO_02492 1.28e-132 yokH - - G - - - SMI1 / KNR4 family
KMEHGPNO_02493 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
KMEHGPNO_02494 9.5e-112 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
KMEHGPNO_02495 6.17e-99 - - - S - - - SMI1-KNR4 cell-wall
KMEHGPNO_02496 1.41e-128 yokK - - S - - - SMI1 / KNR4 family
KMEHGPNO_02497 1.45e-125 - - - J - - - Acetyltransferase (GNAT) domain
KMEHGPNO_02498 1.43e-124 rapK - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
KMEHGPNO_02500 8.56e-85 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
KMEHGPNO_02501 2.8e-86 - - - - - - - -
KMEHGPNO_02503 2.9e-68 - - - S - - - YolD-like protein
KMEHGPNO_02504 1.18e-15 dinB2 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KMEHGPNO_02505 3.38e-178 dinB2 - - L ko:K03502 - ko00000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KMEHGPNO_02506 4.71e-161 - - - C ko:K03303 - ko00000,ko02000 L-lactate permease
KMEHGPNO_02507 7.71e-26 - 2.7.9.1 - G ko:K01006 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Pyruvate phosphate dikinase, PEP/pyruvate binding domain
KMEHGPNO_02508 8.58e-89 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KMEHGPNO_02509 3.53e-77 - - - K - - - Cupin domain
KMEHGPNO_02510 7.92e-87 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
KMEHGPNO_02511 1.87e-74 - - - K - - - Helix-turn-helix
KMEHGPNO_02512 2.11e-49 - - - S - - - TM2 domain
KMEHGPNO_02513 7.53e-157 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
KMEHGPNO_02514 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
KMEHGPNO_02516 1.04e-214 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
KMEHGPNO_02517 3.58e-149 lin0465 - - S - - - DJ-1/PfpI family
KMEHGPNO_02518 6.32e-99 yoaW - - - - - - -
KMEHGPNO_02519 1.06e-200 yoaV - - EG - - - EamA-like transporter family
KMEHGPNO_02520 5.48e-202 yoaU - - K - - - LysR substrate binding domain
KMEHGPNO_02521 1.63e-190 yoaT - - S - - - Protein of unknown function (DUF817)
KMEHGPNO_02522 1.21e-40 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
KMEHGPNO_02523 3.22e-98 yoaS - - S - - - Protein of unknown function (DUF2975)
KMEHGPNO_02524 1.25e-212 yoaR - - V - - - vancomycin resistance protein
KMEHGPNO_02525 5.14e-111 - - - - - - - -
KMEHGPNO_02527 5.14e-292 oxdD 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
KMEHGPNO_02530 2.82e-168 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
KMEHGPNO_02531 9.68e-251 - 4.2.2.10 - G ko:K01732 - ko00000,ko01000 Amb_all
KMEHGPNO_02532 7.3e-145 yoaK - - S - - - Membrane
KMEHGPNO_02533 1.24e-169 yoaJ - - G ko:K20628 - ko00000 Endoglucanase C-terminal domain subunit and related proteins
KMEHGPNO_02534 0.0 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
KMEHGPNO_02535 3.89e-283 yoaH - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 methyl-accepting chemotaxis protein
KMEHGPNO_02536 2.99e-55 - - - S - - - Protein of unknown function (DUF4025)
KMEHGPNO_02537 1.46e-19 - - - - - - - -
KMEHGPNO_02539 1.03e-44 yoaF - - - - - - -
KMEHGPNO_02540 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KMEHGPNO_02541 9.63e-234 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KMEHGPNO_02542 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
KMEHGPNO_02543 5.04e-297 yoaB - - EGP - - - the major facilitator superfamily
KMEHGPNO_02544 2.81e-123 yoaA 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KMEHGPNO_02545 4.82e-179 yoxB - - - - - - -
KMEHGPNO_02546 1.7e-54 yoxC - - S - - - Bacterial protein of unknown function (DUF948)
KMEHGPNO_02547 1.87e-158 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
KMEHGPNO_02548 5.37e-79 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
KMEHGPNO_02549 2.72e-185 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KMEHGPNO_02550 2.33e-262 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KMEHGPNO_02551 2.61e-205 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
KMEHGPNO_02552 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
KMEHGPNO_02553 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
KMEHGPNO_02554 1.01e-200 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
KMEHGPNO_02555 3.42e-198 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
KMEHGPNO_02556 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
KMEHGPNO_02557 3.31e-47 yoeD - - G - - - Helix-turn-helix domain
KMEHGPNO_02558 1.14e-124 - - - L - - - Integrase
KMEHGPNO_02560 7.14e-128 yoeB - - S - - - IseA DL-endopeptidase inhibitor
KMEHGPNO_02561 9.8e-313 yoeA - - V - - - MATE efflux family protein
KMEHGPNO_02562 5.75e-242 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
KMEHGPNO_02563 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
KMEHGPNO_02564 2.15e-90 psiE - - S ko:K13256 - ko00000 Protein PsiE homolog
KMEHGPNO_02565 7.32e-306 yrkQ - - T - - - Histidine kinase
KMEHGPNO_02566 7.15e-164 yrkP - - T ko:K02483 - ko00000,ko02022 Transcriptional regulator
KMEHGPNO_02567 3.57e-281 yrkO - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
KMEHGPNO_02568 4.45e-133 yrkN - - K - - - Acetyltransferase (GNAT) family
KMEHGPNO_02569 5.71e-126 yrkL - - S ko:K11748 - ko00000,ko02000 Flavodoxin-like fold
KMEHGPNO_02570 2.58e-103 - - - S - - - Protein of unknown function with HXXEE motif
KMEHGPNO_02571 9.29e-159 yrkJ - - S ko:K07090 - ko00000 membrane transporter protein
KMEHGPNO_02572 6.46e-49 yrkI - - O - - - Belongs to the sulfur carrier protein TusA family
KMEHGPNO_02573 7.55e-266 yrkH - - P - - - Rhodanese Homology Domain
KMEHGPNO_02574 0.000112 perX - - S - - - DsrE/DsrF-like family
KMEHGPNO_02575 6.55e-126 yrkF - - OP - - - Belongs to the sulfur carrier protein TusA family
KMEHGPNO_02576 6.83e-109 yrkE - - O - - - DsrE/DsrF/DrsH-like family
KMEHGPNO_02577 4.38e-52 yrkD - - S - - - protein conserved in bacteria
KMEHGPNO_02578 2.12e-136 yrkC - - G - - - Cupin domain
KMEHGPNO_02579 1.24e-194 bltR - - K - - - helix_turn_helix, mercury resistance
KMEHGPNO_02580 3.09e-268 blt - - EGP ko:K08153,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
KMEHGPNO_02581 5.29e-109 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
KMEHGPNO_02582 1.33e-293 yrkA - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
KMEHGPNO_02583 7.04e-23 - - - S - - - YrzO-like protein
KMEHGPNO_02584 4.91e-216 yrdR - - EG - - - EamA-like transporter family
KMEHGPNO_02585 1.64e-202 - - - K - - - Transcriptional regulator
KMEHGPNO_02586 1.95e-250 trkA - - P ko:K07222 - ko00000 Oxidoreductase
KMEHGPNO_02587 1.21e-212 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
KMEHGPNO_02589 8.26e-291 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
KMEHGPNO_02590 1.97e-66 azlD - - E - - - Branched-chain amino acid transport protein (AzlD)
KMEHGPNO_02591 6.57e-176 azlC - - E - - - AzlC protein
KMEHGPNO_02592 4.82e-103 bkdR - - K - - - helix_turn_helix ASNC type
KMEHGPNO_02593 7.91e-55 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
KMEHGPNO_02594 7.64e-290 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
KMEHGPNO_02595 2.11e-130 yrdC - - Q - - - Isochorismatase family
KMEHGPNO_02596 1.04e-71 - - - S - - - Protein of unknown function (DUF2568)
KMEHGPNO_02597 1.42e-118 yrdA - - S - - - DinB family
KMEHGPNO_02598 1.48e-212 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
KMEHGPNO_02599 1.27e-247 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
KMEHGPNO_02600 9e-184 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
KMEHGPNO_02601 6.85e-162 yrpD - - S - - - Domain of unknown function, YrpD
KMEHGPNO_02604 1.8e-167 zinT - - S ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
KMEHGPNO_02605 2.5e-121 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
KMEHGPNO_02606 4.03e-238 yrpG - - C - - - Aldo/keto reductase family
KMEHGPNO_02607 2.41e-282 yraO - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
KMEHGPNO_02608 7e-209 yraN - - K - - - Transcriptional regulator
KMEHGPNO_02609 1.15e-260 yraM - - S - - - PrpF protein
KMEHGPNO_02610 2.2e-193 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
KMEHGPNO_02611 5.07e-56 yraL - - S - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KMEHGPNO_02612 5.9e-192 - - - S - - - Alpha beta hydrolase
KMEHGPNO_02613 1.33e-79 - - - T - - - sh3 domain protein
KMEHGPNO_02614 2.92e-81 - - - T - - - sh3 domain protein
KMEHGPNO_02615 6.62e-87 - - - E - - - Glyoxalase-like domain
KMEHGPNO_02616 4.19e-50 yraG - - - ko:K06440 - ko00000 -
KMEHGPNO_02617 9.61e-84 yraF - - M - - - Spore coat protein
KMEHGPNO_02618 3.41e-279 adhB 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
KMEHGPNO_02619 1.23e-35 yraE - - - ko:K06440 - ko00000 -
KMEHGPNO_02620 7.23e-66 yraD - - M ko:K06439 - ko00000 Spore coat protein
KMEHGPNO_02621 3.17e-68 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
KMEHGPNO_02622 4.53e-33 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 peroxiredoxin activity
KMEHGPNO_02623 2.29e-251 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
KMEHGPNO_02624 1.58e-116 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
KMEHGPNO_02625 0.0 sacC 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
KMEHGPNO_02626 1.39e-192 levG - - G ko:K02771,ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
KMEHGPNO_02627 2.79e-166 levF - - G ko:K02746,ko:K02795,ko:K11196 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
KMEHGPNO_02628 6.27e-106 ptnA 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11195 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system mannose fructose sorbose family
KMEHGPNO_02629 1.08e-96 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
KMEHGPNO_02630 0.0 levR - - K - - - PTS system fructose IIA component
KMEHGPNO_02631 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
KMEHGPNO_02632 5.63e-137 yrhP - - E - - - LysE type translocator
KMEHGPNO_02633 5.9e-194 yrhO - - K - - - Archaeal transcriptional regulator TrmB
KMEHGPNO_02634 5.77e-113 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
KMEHGPNO_02635 1.01e-190 rsiV - - S - - - Protein of unknown function (DUF3298)
KMEHGPNO_02636 0.0 oatA - - I - - - Acyltransferase family
KMEHGPNO_02637 6.32e-59 yrhK - - S - - - YrhK-like protein
KMEHGPNO_02638 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
KMEHGPNO_02639 2.26e-135 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
KMEHGPNO_02640 1.05e-124 yrhH - - Q - - - methyltransferase
KMEHGPNO_02641 9.39e-08 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
KMEHGPNO_02643 1.38e-183 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
KMEHGPNO_02644 4.41e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
KMEHGPNO_02645 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
KMEHGPNO_02646 1.22e-102 yrhD - - S - - - Protein of unknown function (DUF1641)
KMEHGPNO_02647 6.93e-49 yrhC - - S - - - YrhC-like protein
KMEHGPNO_02648 8.55e-269 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
KMEHGPNO_02649 1.66e-216 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
KMEHGPNO_02650 5.64e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KMEHGPNO_02651 2.83e-152 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
KMEHGPNO_02652 4.94e-36 yrzA - - S - - - Protein of unknown function (DUF2536)
KMEHGPNO_02653 1.42e-102 yrrS - - S - - - Protein of unknown function (DUF1510)
KMEHGPNO_02654 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
KMEHGPNO_02655 1.14e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KMEHGPNO_02656 4.51e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
KMEHGPNO_02657 4.62e-313 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
KMEHGPNO_02658 6.3e-222 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
KMEHGPNO_02659 1.4e-154 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
KMEHGPNO_02660 4.34e-241 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KMEHGPNO_02661 2.94e-60 yrzB - - S - - - Belongs to the UPF0473 family
KMEHGPNO_02662 5.49e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KMEHGPNO_02663 2.22e-55 yrzL - - S - - - Belongs to the UPF0297 family
KMEHGPNO_02664 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KMEHGPNO_02665 1.25e-241 yrrI - - S - - - AI-2E family transporter
KMEHGPNO_02666 2.21e-168 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
KMEHGPNO_02667 1.01e-184 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
KMEHGPNO_02668 1.6e-76 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KMEHGPNO_02669 1.85e-47 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KMEHGPNO_02670 9.26e-140 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KMEHGPNO_02671 5.38e-12 - - - S - - - Protein of unknown function (DUF3918)
KMEHGPNO_02672 8.4e-42 yrzR - - - - - - -
KMEHGPNO_02673 1.44e-107 yrrD - - S - - - protein conserved in bacteria
KMEHGPNO_02674 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KMEHGPNO_02675 1.01e-20 yrrB - - S - - - COG0457 FOG TPR repeat
KMEHGPNO_02676 5.64e-279 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KMEHGPNO_02677 2.19e-269 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
KMEHGPNO_02678 8.12e-93 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
KMEHGPNO_02679 6.69e-301 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
KMEHGPNO_02680 2.29e-176 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
KMEHGPNO_02681 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KMEHGPNO_02682 7.37e-311 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
KMEHGPNO_02684 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
KMEHGPNO_02685 1.36e-90 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KMEHGPNO_02686 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KMEHGPNO_02687 2.53e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KMEHGPNO_02688 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
KMEHGPNO_02689 1.07e-64 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
KMEHGPNO_02690 6.51e-114 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
KMEHGPNO_02691 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KMEHGPNO_02692 5.53e-65 yrzD - - S - - - Post-transcriptional regulator
KMEHGPNO_02693 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KMEHGPNO_02694 1.23e-144 yrbG - - S - - - membrane
KMEHGPNO_02695 3.59e-97 yrzE - - S - - - Protein of unknown function (DUF3792)
KMEHGPNO_02696 1.29e-52 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
KMEHGPNO_02697 4.74e-292 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KMEHGPNO_02698 6.03e-248 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KMEHGPNO_02699 2.39e-29 yrzS - - S - - - Protein of unknown function (DUF2905)
KMEHGPNO_02700 9.14e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KMEHGPNO_02701 2.84e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KMEHGPNO_02702 6.46e-121 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
KMEHGPNO_02703 0.0 csbX - - EGP - - - the major facilitator superfamily
KMEHGPNO_02704 1.13e-247 idhA 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
KMEHGPNO_02705 1.91e-151 yrzF - - T - - - serine threonine protein kinase
KMEHGPNO_02707 2.09e-66 - - - S - - - Family of unknown function (DUF5412)
KMEHGPNO_02709 0.0 yrbD - - E ko:K03310 - ko00000 Sodium alanine symporter
KMEHGPNO_02710 4.99e-164 yebC - - K - - - transcriptional regulatory protein
KMEHGPNO_02711 2.55e-70 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KMEHGPNO_02712 2.43e-217 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
KMEHGPNO_02713 1.87e-271 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KMEHGPNO_02714 5.92e-201 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
KMEHGPNO_02715 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
KMEHGPNO_02716 3.9e-276 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
KMEHGPNO_02717 1.44e-122 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
KMEHGPNO_02718 1.43e-208 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
KMEHGPNO_02719 4.75e-96 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
KMEHGPNO_02720 5.59e-308 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KMEHGPNO_02721 4.25e-139 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
KMEHGPNO_02722 2.7e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
KMEHGPNO_02723 2.66e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
KMEHGPNO_02724 6.34e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
KMEHGPNO_02725 3.74e-208 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
KMEHGPNO_02726 3.03e-186 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
KMEHGPNO_02727 6.84e-185 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
KMEHGPNO_02728 4.3e-158 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
KMEHGPNO_02729 8.72e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
KMEHGPNO_02730 7.78e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
KMEHGPNO_02731 5.26e-235 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
KMEHGPNO_02732 1.39e-161 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
KMEHGPNO_02733 7.06e-132 maf - - D ko:K06287 - ko00000 septum formation protein Maf
KMEHGPNO_02734 4.28e-211 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
KMEHGPNO_02735 3.08e-162 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
KMEHGPNO_02736 8.99e-315 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
KMEHGPNO_02737 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KMEHGPNO_02738 1.53e-35 - - - - - - - -
KMEHGPNO_02739 4.82e-252 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KMEHGPNO_02740 0.0 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
KMEHGPNO_02741 1.38e-309 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
KMEHGPNO_02742 3.7e-233 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
KMEHGPNO_02743 1.01e-183 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
KMEHGPNO_02744 8.91e-220 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
KMEHGPNO_02745 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
KMEHGPNO_02746 6.39e-316 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KMEHGPNO_02747 3.92e-115 ysxD - - - - - - -
KMEHGPNO_02748 7.6e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
KMEHGPNO_02749 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KMEHGPNO_02750 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
KMEHGPNO_02751 1.15e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KMEHGPNO_02752 2.09e-285 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KMEHGPNO_02753 3.19e-239 ysoA - - H - - - Tetratricopeptide repeat
KMEHGPNO_02754 1.48e-147 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KMEHGPNO_02755 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KMEHGPNO_02756 1.23e-254 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
KMEHGPNO_02757 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KMEHGPNO_02758 5.55e-244 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KMEHGPNO_02759 5.05e-110 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
KMEHGPNO_02760 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
KMEHGPNO_02762 2.83e-99 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
KMEHGPNO_02763 3.34e-205 - - - N - - - domain, Protein
KMEHGPNO_02764 3.36e-181 ysnF - - S - - - protein conserved in bacteria
KMEHGPNO_02766 4.05e-119 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
KMEHGPNO_02767 7.86e-132 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KMEHGPNO_02768 7.12e-171 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KMEHGPNO_02769 3.27e-255 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
KMEHGPNO_02770 3.69e-193 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
KMEHGPNO_02771 1.6e-98 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
KMEHGPNO_02772 1.81e-41 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
KMEHGPNO_02773 2.65e-102 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
KMEHGPNO_02774 2.33e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
KMEHGPNO_02775 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
KMEHGPNO_02776 1.35e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
KMEHGPNO_02777 8.53e-104 yslB - - S - - - Protein of unknown function (DUF2507)
KMEHGPNO_02778 3.96e-275 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
KMEHGPNO_02779 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KMEHGPNO_02780 1.12e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
KMEHGPNO_02781 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
KMEHGPNO_02782 5.84e-226 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
KMEHGPNO_02783 2.58e-179 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
KMEHGPNO_02784 2.56e-175 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
KMEHGPNO_02785 5.74e-129 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
KMEHGPNO_02786 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KMEHGPNO_02787 3.76e-89 yshE - - S ko:K08989 - ko00000 membrane
KMEHGPNO_02788 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KMEHGPNO_02789 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
KMEHGPNO_02790 1.09e-111 yshB - - S - - - membrane protein, required for colicin V production
KMEHGPNO_02791 1.04e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KMEHGPNO_02792 2.76e-218 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KMEHGPNO_02793 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KMEHGPNO_02794 1.81e-250 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KMEHGPNO_02795 1.81e-170 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KMEHGPNO_02796 4.37e-43 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
KMEHGPNO_02797 1.45e-259 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
KMEHGPNO_02798 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Glycolate oxidase subunit
KMEHGPNO_02799 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
KMEHGPNO_02800 2.81e-67 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase-like domain
KMEHGPNO_02801 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
KMEHGPNO_02802 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
KMEHGPNO_02803 1.49e-190 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
KMEHGPNO_02804 6.77e-219 araP - - G ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
KMEHGPNO_02805 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
KMEHGPNO_02806 1.65e-285 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
KMEHGPNO_02807 2.03e-185 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
KMEHGPNO_02808 1.7e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
KMEHGPNO_02809 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
KMEHGPNO_02810 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
KMEHGPNO_02811 9.92e-242 - 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
KMEHGPNO_02812 4.35e-262 ysdC - - G - - - COG1363 Cellulase M and related proteins
KMEHGPNO_02813 2.29e-88 ysdB - - S - - - Sigma-w pathway protein YsdB
KMEHGPNO_02814 1.27e-59 ysdA - - S - - - Membrane
KMEHGPNO_02815 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KMEHGPNO_02816 3.93e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
KMEHGPNO_02817 1.81e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KMEHGPNO_02819 5.34e-150 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
KMEHGPNO_02820 2e-83 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
KMEHGPNO_02821 9.32e-165 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
KMEHGPNO_02822 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KMEHGPNO_02823 1.2e-190 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
KMEHGPNO_02824 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KMEHGPNO_02826 3.46e-205 ytxC - - S - - - YtxC-like family
KMEHGPNO_02827 1.33e-141 ytxB - - S - - - SNARE associated Golgi protein
KMEHGPNO_02828 1e-219 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
KMEHGPNO_02829 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
KMEHGPNO_02830 2.42e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KMEHGPNO_02831 2.42e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KMEHGPNO_02832 1.22e-246 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KMEHGPNO_02833 1.15e-86 ytcD - - K - - - Transcriptional regulator
KMEHGPNO_02834 1.28e-258 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
KMEHGPNO_02835 4.54e-205 ytbE - - S - - - reductase
KMEHGPNO_02836 2.82e-126 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KMEHGPNO_02837 1.68e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
KMEHGPNO_02838 4.05e-202 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KMEHGPNO_02839 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KMEHGPNO_02840 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
KMEHGPNO_02841 3.27e-169 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KMEHGPNO_02842 1.04e-217 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
KMEHGPNO_02843 9.27e-309 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
KMEHGPNO_02844 1.17e-267 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
KMEHGPNO_02845 9.38e-95 ytwI - - S - - - membrane
KMEHGPNO_02846 2.73e-245 ytvI - - S - - - sporulation integral membrane protein YtvI
KMEHGPNO_02847 3.16e-80 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
KMEHGPNO_02848 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
KMEHGPNO_02849 4.65e-229 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KMEHGPNO_02850 9.82e-234 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
KMEHGPNO_02851 1.46e-206 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KMEHGPNO_02852 8.53e-287 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
KMEHGPNO_02853 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
KMEHGPNO_02854 2.45e-75 ytrH - - S - - - Sporulation protein YtrH
KMEHGPNO_02855 2.08e-111 ytrI - - - - - - -
KMEHGPNO_02856 1.15e-39 - - - - - - - -
KMEHGPNO_02857 7.15e-230 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
KMEHGPNO_02858 2.15e-63 ytpI - - S - - - YtpI-like protein
KMEHGPNO_02859 1.13e-308 ytoI - - K - - - transcriptional regulator containing CBS domains
KMEHGPNO_02860 1.91e-166 ytkL - - S - - - Belongs to the UPF0173 family
KMEHGPNO_02861 8.04e-182 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KMEHGPNO_02863 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
KMEHGPNO_02864 4.3e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
KMEHGPNO_02865 3.87e-113 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
KMEHGPNO_02866 4.69e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KMEHGPNO_02867 3.78e-224 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
KMEHGPNO_02868 1.93e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KMEHGPNO_02869 1.06e-94 ytfJ - - S - - - Sporulation protein YtfJ
KMEHGPNO_02870 5.87e-149 ytfI - - S - - - Protein of unknown function (DUF2953)
KMEHGPNO_02871 4.08e-112 yteJ - - S - - - RDD family
KMEHGPNO_02872 2.39e-230 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
KMEHGPNO_02873 1.39e-188 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KMEHGPNO_02874 0.0 ytcJ - - S - - - amidohydrolase
KMEHGPNO_02875 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
KMEHGPNO_02876 2.12e-40 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
KMEHGPNO_02877 6.26e-289 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KMEHGPNO_02878 3.73e-264 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
KMEHGPNO_02879 1.17e-304 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
KMEHGPNO_02880 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KMEHGPNO_02881 5.29e-198 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
KMEHGPNO_02882 1.2e-141 yttP - - K - - - Transcriptional regulator
KMEHGPNO_02883 1.87e-112 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
KMEHGPNO_02884 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
KMEHGPNO_02885 2.01e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KMEHGPNO_02887 5.31e-303 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KMEHGPNO_02888 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
KMEHGPNO_02889 3.46e-156 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
KMEHGPNO_02890 6.16e-152 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
KMEHGPNO_02891 1.81e-290 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
KMEHGPNO_02892 1.6e-161 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
KMEHGPNO_02893 6.84e-187 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
KMEHGPNO_02894 4.16e-235 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
KMEHGPNO_02895 7.64e-250 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
KMEHGPNO_02896 3.7e-70 ytxJ - - O - - - Protein of unknown function (DUF2847)
KMEHGPNO_02897 3.17e-30 ytxH - - S - - - COG4980 Gas vesicle protein
KMEHGPNO_02898 1.67e-63 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KMEHGPNO_02899 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
KMEHGPNO_02900 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
KMEHGPNO_02901 1.78e-140 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KMEHGPNO_02902 1.02e-191 ytpQ - - S - - - Belongs to the UPF0354 family
KMEHGPNO_02903 3.17e-75 ytpP - - CO - - - Thioredoxin
KMEHGPNO_02904 7.02e-103 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
KMEHGPNO_02905 3.71e-261 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
KMEHGPNO_02906 1.17e-67 ytzB - - S - - - small secreted protein
KMEHGPNO_02907 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
KMEHGPNO_02908 2.61e-191 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
KMEHGPNO_02909 3.07e-156 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KMEHGPNO_02910 9.51e-61 ytzH - - S - - - YtzH-like protein
KMEHGPNO_02911 3.02e-192 ytmP - - M - - - Phosphotransferase
KMEHGPNO_02912 0.0 amyX 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
KMEHGPNO_02913 5.24e-230 ytlR - - I - - - Diacylglycerol kinase catalytic domain
KMEHGPNO_02914 2e-211 ytlQ - - - - - - -
KMEHGPNO_02915 1.44e-128 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KMEHGPNO_02916 3e-221 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
KMEHGPNO_02917 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
KMEHGPNO_02918 7.02e-288 pbuO - - S ko:K06901 - ko00000,ko02000 permease
KMEHGPNO_02919 1.67e-253 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
KMEHGPNO_02920 9.39e-167 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
KMEHGPNO_02921 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
KMEHGPNO_02922 7.43e-170 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
KMEHGPNO_02923 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KMEHGPNO_02924 6.99e-294 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
KMEHGPNO_02925 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
KMEHGPNO_02926 2.14e-36 yteV - - S - - - Sporulation protein Cse60
KMEHGPNO_02927 2.3e-151 yteU - - S - - - Integral membrane protein
KMEHGPNO_02928 0.0 yteT - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
KMEHGPNO_02929 4.78e-94 yteS - - G - - - transport
KMEHGPNO_02930 1.88e-275 yteR 3.2.1.172 GH105 G ko:K15532 - ko00000,ko01000 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
KMEHGPNO_02931 1.53e-219 lplB13 - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
KMEHGPNO_02932 0.0 ytdP - - K - - - Transcriptional regulator
KMEHGPNO_02933 0.0 - - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
KMEHGPNO_02934 1.02e-191 ytcP - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
KMEHGPNO_02935 1.28e-177 ytbQ 1.1.1.203, 1.1.1.388 - GM ko:K18981,ko:K19243 ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 NAD dependent epimerase/dehydratase family
KMEHGPNO_02936 1.29e-278 bioI 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
KMEHGPNO_02937 2.08e-240 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KMEHGPNO_02938 1.09e-158 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KMEHGPNO_02939 1.56e-276 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
KMEHGPNO_02940 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
KMEHGPNO_02941 1.24e-176 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
KMEHGPNO_02942 1.13e-219 - - - S - - - Acetyl xylan esterase (AXE1)
KMEHGPNO_02943 2.64e-243 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
KMEHGPNO_02944 3.36e-308 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
KMEHGPNO_02945 1.66e-214 amyD - - P ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KMEHGPNO_02946 7.65e-186 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
KMEHGPNO_02947 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
KMEHGPNO_02948 1.22e-68 ytwF - - P - - - Sulfurtransferase
KMEHGPNO_02949 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
KMEHGPNO_02950 3.63e-72 ytvB - - S - - - Protein of unknown function (DUF4257)
KMEHGPNO_02951 3.82e-183 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
KMEHGPNO_02952 8.54e-269 yttB - - EGP - - - Major facilitator superfamily
KMEHGPNO_02953 9.37e-77 yttA - - S - - - Pfam Transposase IS66
KMEHGPNO_02954 0.0 bceB - - V ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
KMEHGPNO_02955 1.28e-177 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
KMEHGPNO_02956 1.14e-232 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
KMEHGPNO_02957 1.06e-165 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KMEHGPNO_02958 9.81e-297 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
KMEHGPNO_02959 5.88e-163 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
KMEHGPNO_02960 9.3e-184 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
KMEHGPNO_02961 1.74e-195 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
KMEHGPNO_02962 5.96e-207 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
KMEHGPNO_02963 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
KMEHGPNO_02965 1.27e-55 ytzC - - S - - - Protein of unknown function (DUF2524)
KMEHGPNO_02966 2.35e-244 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
KMEHGPNO_02967 9.61e-137 ytqB - - J - - - Putative rRNA methylase
KMEHGPNO_02968 2.78e-275 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
KMEHGPNO_02969 1.57e-190 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
KMEHGPNO_02970 5.88e-88 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KMEHGPNO_02971 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
KMEHGPNO_02972 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
KMEHGPNO_02973 2.26e-286 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KMEHGPNO_02974 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KMEHGPNO_02975 2.85e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
KMEHGPNO_02976 5.48e-190 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
KMEHGPNO_02977 1.87e-240 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
KMEHGPNO_02978 6.12e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
KMEHGPNO_02979 1.32e-183 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
KMEHGPNO_02980 4.47e-113 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
KMEHGPNO_02981 3.2e-81 ytkC - - S - - - Bacteriophage holin family
KMEHGPNO_02982 1.8e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
KMEHGPNO_02984 6.79e-95 ytkA - - S - - - YtkA-like
KMEHGPNO_02985 8.36e-113 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KMEHGPNO_02986 1.27e-133 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
KMEHGPNO_02987 5.02e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
KMEHGPNO_02988 1.03e-315 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
KMEHGPNO_02989 3.3e-238 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
KMEHGPNO_02990 2.84e-33 - - - S - - - Domain of Unknown Function (DUF1540)
KMEHGPNO_02991 3.09e-190 mntD - - P ko:K11709,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
KMEHGPNO_02992 6.11e-295 mntC - - P ko:K11705,ko:K11708,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
KMEHGPNO_02993 3.97e-175 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K11710,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
KMEHGPNO_02994 1.53e-216 troA - - P ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
KMEHGPNO_02995 5.81e-272 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
KMEHGPNO_02996 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
KMEHGPNO_02997 3.45e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KMEHGPNO_02998 1.63e-195 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
KMEHGPNO_02999 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KMEHGPNO_03000 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
KMEHGPNO_03001 8.68e-169 yteA - - T - - - COG1734 DnaK suppressor protein
KMEHGPNO_03002 6.12e-190 ytdA 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
KMEHGPNO_03003 7.94e-308 ytcA 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KMEHGPNO_03004 4.3e-228 ytcB - - M - - - NAD-dependent epimerase dehydratase
KMEHGPNO_03005 3.4e-296 - - - M ko:K06338 - ko00000 Glycosyltransferase Family 4
KMEHGPNO_03007 2.82e-262 cotS - - S ko:K06337 - ko00000 Seems to be required for the assembly of the CotSA protein in spores
KMEHGPNO_03008 1.68e-274 cotSA - - M ko:K06338 - ko00000 Glycosyl transferases group 1
KMEHGPNO_03009 6.11e-259 cotI - - S ko:K06331 - ko00000 Spore coat protein
KMEHGPNO_03010 6.61e-100 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
KMEHGPNO_03011 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KMEHGPNO_03012 0.0 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
KMEHGPNO_03013 1.07e-237 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Glucose-1-phosphate adenylyltransferase, GlgD subunit
KMEHGPNO_03014 8.49e-265 glgC 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KMEHGPNO_03015 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KMEHGPNO_03033 4.02e-201 ydhU - - P ko:K07217 - ko00000 Catalase
KMEHGPNO_03034 1.12e-269 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
KMEHGPNO_03035 6.94e-238 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
KMEHGPNO_03036 1.21e-214 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
KMEHGPNO_03037 7.44e-169 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
KMEHGPNO_03038 0.0 ydhP 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KMEHGPNO_03039 6.23e-303 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KMEHGPNO_03040 4.82e-67 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KMEHGPNO_03041 1.88e-63 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KMEHGPNO_03042 6.3e-255 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
KMEHGPNO_03043 2.59e-126 ydhK - - M - - - Protein of unknown function (DUF1541)
KMEHGPNO_03044 6.35e-230 ydhJ - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
KMEHGPNO_03045 1.04e-105 - - - K - - - Acetyltransferase (GNAT) domain
KMEHGPNO_03047 6.48e-87 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
KMEHGPNO_03048 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
KMEHGPNO_03049 6.08e-163 - - - - - - - -
KMEHGPNO_03050 1.37e-289 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
KMEHGPNO_03051 2.1e-308 ydhD - - M - - - Glycosyl hydrolase
KMEHGPNO_03052 7.45e-158 ydhC - - K - - - FCD
KMEHGPNO_03053 2.51e-155 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
KMEHGPNO_03054 9.46e-264 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
KMEHGPNO_03055 3.29e-90 - - - K - - - Winged helix DNA-binding domain
KMEHGPNO_03056 6.42e-147 ydgI - - C - - - nitroreductase
KMEHGPNO_03057 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
KMEHGPNO_03058 8.12e-104 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
KMEHGPNO_03059 1.4e-116 - - - S - - - DinB family
KMEHGPNO_03060 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
KMEHGPNO_03061 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
KMEHGPNO_03062 3.15e-108 yycN - - K - - - Acetyltransferase
KMEHGPNO_03063 6.73e-69 - - - S - - - DoxX-like family
KMEHGPNO_03064 4.92e-127 ydgC - - K - - - Bacterial regulatory proteins, tetR family
KMEHGPNO_03065 8.97e-47 ydgB - - S - - - Spore germination protein gerPA/gerPF
KMEHGPNO_03066 1.53e-47 ydgA - - S - - - Spore germination protein gerPA/gerPF
KMEHGPNO_03067 2.57e-89 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
KMEHGPNO_03068 8.96e-160 ydfS - - S - - - Protein of unknown function (DUF421)
KMEHGPNO_03069 9.94e-40 ydfR - - S - - - Protein of unknown function (DUF421)
KMEHGPNO_03070 9.11e-65 ydfR - - S - - - Protein of unknown function (DUF421)
KMEHGPNO_03072 4.57e-40 - - - - - - - -
KMEHGPNO_03073 2.4e-21 ydgA - - S - - - Spore germination protein gerPA/gerPF
KMEHGPNO_03074 3.11e-73 ydfQ - - CO - - - Thioredoxin
KMEHGPNO_03075 8.02e-84 ydfP - - S ko:K15977 - ko00000 DoxX
KMEHGPNO_03076 4.51e-237 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
KMEHGPNO_03077 1.51e-139 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
KMEHGPNO_03078 5e-197 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KMEHGPNO_03079 8.33e-187 - - - K - - - Bacterial transcription activator, effector binding domain
KMEHGPNO_03080 1.31e-149 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
KMEHGPNO_03081 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
KMEHGPNO_03082 2.3e-142 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KMEHGPNO_03083 1.37e-251 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KMEHGPNO_03085 3.92e-104 - - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KMEHGPNO_03086 1.5e-158 ydfF - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
KMEHGPNO_03087 9.91e-150 ydfE - - S - - - Flavin reductase like domain
KMEHGPNO_03088 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KMEHGPNO_03089 1.27e-186 - - - EG - - - EamA-like transporter family
KMEHGPNO_03090 3.34e-158 - - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
KMEHGPNO_03091 7.61e-279 - - - T - - - GHKL domain
KMEHGPNO_03092 2.52e-199 - - - - - - - -
KMEHGPNO_03093 1.45e-157 nodB1 - - G - - - deacetylase
KMEHGPNO_03094 4.78e-191 - - - K - - - Transcriptional regulator
KMEHGPNO_03095 6.09e-182 - - - J - - - GNAT acetyltransferase
KMEHGPNO_03096 2.38e-292 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KMEHGPNO_03097 1.22e-74 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
KMEHGPNO_03098 6.56e-194 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
KMEHGPNO_03099 2.49e-73 - - - K - - - HxlR-like helix-turn-helix
KMEHGPNO_03100 1.39e-134 - - - S ko:K07002 - ko00000 Serine hydrolase
KMEHGPNO_03101 4.3e-96 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
KMEHGPNO_03102 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KMEHGPNO_03103 1.49e-193 ydeK - - EG - - - -transporter
KMEHGPNO_03104 1.96e-146 - - - - - - - -
KMEHGPNO_03105 5.52e-133 ydeI - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
KMEHGPNO_03106 7.89e-71 ydeH - - - - - - -
KMEHGPNO_03107 2.67e-277 ydeG - - EGP - - - Major facilitator superfamily
KMEHGPNO_03108 0.0 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KMEHGPNO_03109 3.91e-211 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
KMEHGPNO_03110 5.34e-219 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KMEHGPNO_03111 1.03e-207 - - - K - - - AraC-like ligand binding domain
KMEHGPNO_03112 6.72e-41 ydzE - - EG - - - spore germination
KMEHGPNO_03113 2.07e-102 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
KMEHGPNO_03114 4.22e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
KMEHGPNO_03115 5.08e-91 ydeA - - S - - - DJ-1/PfpI family
KMEHGPNO_03120 1.45e-282 ydeG3 - - EGP - - - Major Facilitator Superfamily
KMEHGPNO_03121 1.34e-184 yddR - - S - - - Zn-dependent hydrolases of the beta-lactamase fold
KMEHGPNO_03122 1.62e-128 yddQ - - Q - - - Isochorismatase family
KMEHGPNO_03123 1.26e-101 lrpB - - K ko:K03719 - ko00000,ko03000,ko03036 transcriptional
KMEHGPNO_03124 8.15e-94 lrpA - - K ko:K03719 - ko00000,ko03000,ko03036 transcriptional
KMEHGPNO_03125 6.69e-239 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KMEHGPNO_03133 1.59e-109 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
KMEHGPNO_03134 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
KMEHGPNO_03135 1.54e-101 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
KMEHGPNO_03136 1.32e-106 ydcG - - S - - - EVE domain
KMEHGPNO_03140 7.57e-141 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
KMEHGPNO_03141 1.55e-178 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KMEHGPNO_03142 2.48e-111 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
KMEHGPNO_03143 1.97e-70 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
KMEHGPNO_03144 1.31e-243 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
KMEHGPNO_03145 2.45e-89 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
KMEHGPNO_03146 1.8e-74 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
KMEHGPNO_03147 8.58e-184 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
KMEHGPNO_03148 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
KMEHGPNO_03149 9.49e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
KMEHGPNO_03150 1.77e-282 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KMEHGPNO_03151 4.66e-234 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
KMEHGPNO_03152 1.32e-76 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KMEHGPNO_03153 4.21e-138 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
KMEHGPNO_03154 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
KMEHGPNO_03155 2.12e-107 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
KMEHGPNO_03156 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KMEHGPNO_03157 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KMEHGPNO_03158 4.18e-256 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
KMEHGPNO_03159 4.19e-75 ydbP - - CO - - - Thioredoxin
KMEHGPNO_03160 2.72e-202 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KMEHGPNO_03162 1.49e-26 - - - S - - - Fur-regulated basic protein B
KMEHGPNO_03163 2.49e-278 ydbM - - I - - - acyl-CoA dehydrogenase
KMEHGPNO_03164 9.32e-70 ydbL - - - - - - -
KMEHGPNO_03165 2.99e-159 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
KMEHGPNO_03166 4.59e-219 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KMEHGPNO_03167 1.32e-230 ydbI - - S - - - AI-2E family transporter
KMEHGPNO_03168 3.64e-289 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KMEHGPNO_03169 3.39e-155 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
KMEHGPNO_03170 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
KMEHGPNO_03171 3.66e-253 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
KMEHGPNO_03172 2.24e-197 ydbD - - P ko:K07217 - ko00000 Catalase
KMEHGPNO_03173 5.01e-80 ydbC - - S - - - Domain of unknown function (DUF4937
KMEHGPNO_03174 1.07e-75 ydbB - - G - - - Cupin domain
KMEHGPNO_03175 8.37e-11 gsiB - - S ko:K06884 - ko00000 general stress protein
KMEHGPNO_03176 4.3e-190 ydbA - - P - - - EcsC protein family
KMEHGPNO_03177 2.25e-100 ydaT - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
KMEHGPNO_03178 1.67e-42 ydaS - - S - - - membrane
KMEHGPNO_03179 3.9e-286 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
KMEHGPNO_03180 6.14e-53 - - - - - - - -
KMEHGPNO_03181 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
KMEHGPNO_03182 7.28e-101 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
KMEHGPNO_03183 0.0 ydaO - - E - - - amino acid
KMEHGPNO_03184 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
KMEHGPNO_03185 1.12e-303 ydaM - - M - - - Glycosyl transferase family group 2
KMEHGPNO_03186 4.53e-275 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
KMEHGPNO_03187 2.34e-108 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
KMEHGPNO_03188 3.66e-192 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
KMEHGPNO_03189 3.31e-262 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
KMEHGPNO_03190 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KMEHGPNO_03191 3.95e-98 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
KMEHGPNO_03192 1.09e-61 ydzA - - EGP - - - Domain of unknown function (DUF3817)
KMEHGPNO_03193 1.31e-178 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
KMEHGPNO_03194 5.24e-101 ydaG - - S - - - general stress protein
KMEHGPNO_03195 1.1e-132 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KMEHGPNO_03196 2.36e-126 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
KMEHGPNO_03197 3.74e-207 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KMEHGPNO_03198 3.36e-126 ydaC - - Q - - - Methyltransferase domain
KMEHGPNO_03199 0.0 ydaB - - IQ - - - acyl-CoA ligase
KMEHGPNO_03200 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
KMEHGPNO_03201 1.09e-222 ycsN - - S - - - Oxidoreductase
KMEHGPNO_03202 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
KMEHGPNO_03203 8.97e-65 yczJ - - S - - - biosynthesis
KMEHGPNO_03205 6.66e-151 ycsK - - E - - - anatomical structure formation involved in morphogenesis
KMEHGPNO_03206 1.55e-170 kipR - - K - - - Transcriptional regulator
KMEHGPNO_03207 9.48e-237 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
KMEHGPNO_03208 4.84e-171 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
KMEHGPNO_03209 1.93e-187 ycsI - - S - - - Belongs to the D-glutamate cyclase family
KMEHGPNO_03210 2.78e-273 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
KMEHGPNO_03211 3.67e-179 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
KMEHGPNO_03212 1.9e-177 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
KMEHGPNO_03214 1.89e-87 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
KMEHGPNO_03215 2.73e-140 - - - Q - - - COG0412 Dienelactone hydrolase and related enzymes
KMEHGPNO_03216 1.25e-96 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
KMEHGPNO_03218 1.01e-256 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
KMEHGPNO_03219 2.97e-266 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
KMEHGPNO_03220 8.3e-95 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
KMEHGPNO_03221 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
KMEHGPNO_03222 4.67e-75 - - - - - - - -
KMEHGPNO_03223 2.88e-136 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
KMEHGPNO_03224 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
KMEHGPNO_03225 3.99e-134 ycnI - - S - - - protein conserved in bacteria
KMEHGPNO_03226 5.9e-187 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KMEHGPNO_03227 1.67e-190 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
KMEHGPNO_03231 7.42e-144 - - - V ko:K20485 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 ABC-type multidrug transport system, ATPase and permease
KMEHGPNO_03232 7.04e-162 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
KMEHGPNO_03233 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KMEHGPNO_03234 1.89e-310 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KMEHGPNO_03235 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KMEHGPNO_03236 6.51e-69 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
KMEHGPNO_03237 1.68e-60 ycnE - - S - - - Monooxygenase
KMEHGPNO_03238 8.65e-174 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Oxidoreductase
KMEHGPNO_03239 2.91e-198 ycnC - - K - - - Transcriptional regulator
KMEHGPNO_03240 0.0 ycnB - - EGP - - - the major facilitator superfamily
KMEHGPNO_03241 4.69e-212 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
KMEHGPNO_03242 2.29e-175 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KMEHGPNO_03243 3.16e-209 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KMEHGPNO_03244 1.09e-205 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KMEHGPNO_03245 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
KMEHGPNO_03247 1.58e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
KMEHGPNO_03249 2.18e-97 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
KMEHGPNO_03250 0.0 yclK - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
KMEHGPNO_03251 2.23e-165 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KMEHGPNO_03252 1.35e-276 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
KMEHGPNO_03253 8e-154 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
KMEHGPNO_03254 1.33e-253 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
KMEHGPNO_03255 8.01e-295 gerKC - - S ko:K06297 - ko00000 spore germination
KMEHGPNO_03256 0.0 gerKA - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
KMEHGPNO_03258 0.0 yclG - - M - - - Pectate lyase superfamily protein
KMEHGPNO_03259 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
KMEHGPNO_03260 8.75e-199 yclE 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Alpha beta hydrolase
KMEHGPNO_03261 2.32e-104 yclD - - - - - - -
KMEHGPNO_03262 4.02e-52 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
KMEHGPNO_03263 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
KMEHGPNO_03264 3.72e-139 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
KMEHGPNO_03265 5.32e-209 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
KMEHGPNO_03266 3.54e-187 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
KMEHGPNO_03267 4.6e-157 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
KMEHGPNO_03268 7.11e-172 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
KMEHGPNO_03269 8.71e-148 yczE - - S ko:K07149 - ko00000 membrane
KMEHGPNO_03270 4.76e-145 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
KMEHGPNO_03271 0.0 ycxD - - K - - - GntR family transcriptional regulator
KMEHGPNO_03272 6.59e-205 ycxC - - EG - - - EamA-like transporter family
KMEHGPNO_03273 1.48e-122 - - - S - - - YcxB-like protein
KMEHGPNO_03274 2.66e-289 - - - EGP - - - Major Facilitator Superfamily
KMEHGPNO_03275 1.91e-178 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
KMEHGPNO_03276 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
KMEHGPNO_03277 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KMEHGPNO_03278 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KMEHGPNO_03279 6.05e-86 hxlR - - K - - - transcriptional
KMEHGPNO_03280 3.26e-136 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
KMEHGPNO_03281 5.38e-125 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
KMEHGPNO_03282 5.32e-268 tlpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
KMEHGPNO_03283 7.94e-100 nucA - - M - - - Deoxyribonuclease NucA/NucB
KMEHGPNO_03284 4.78e-91 nin - - S - - - Competence protein J (ComJ)
KMEHGPNO_03285 0.0 yckE 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KMEHGPNO_03286 8.33e-68 yckD - - S - - - Protein of unknown function (DUF2680)
KMEHGPNO_03287 9.11e-31 yckC - - S - - - membrane
KMEHGPNO_03289 6.23e-186 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
KMEHGPNO_03290 4.96e-148 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
KMEHGPNO_03291 9.24e-289 yciC - - S - - - GTPases (G3E family)
KMEHGPNO_03292 3.49e-139 - - - M - - - ErfK YbiS YcfS YnhG
KMEHGPNO_03293 6.79e-219 folE2 3.5.4.16 - S ko:K09007 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Converts GTP to 7,8-dihydroneopterin triphosphate
KMEHGPNO_03294 3.18e-282 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
KMEHGPNO_03295 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
KMEHGPNO_03296 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KMEHGPNO_03297 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KMEHGPNO_03298 1.2e-74 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
KMEHGPNO_03299 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
KMEHGPNO_03300 2.01e-243 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
KMEHGPNO_03301 4.02e-201 ycgS - - I - - - alpha/beta hydrolase fold
KMEHGPNO_03302 9.14e-187 ycgR - - S ko:K07089 - ko00000 permeases
KMEHGPNO_03303 3.82e-195 ycgQ - - S ko:K08986 - ko00000 membrane
KMEHGPNO_03304 3.92e-288 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
KMEHGPNO_03305 0.0 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KMEHGPNO_03306 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
KMEHGPNO_03307 3.63e-218 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
KMEHGPNO_03308 3.03e-184 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
KMEHGPNO_03309 4.48e-231 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
KMEHGPNO_03310 4.63e-227 ycgK - - K ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 LysR substrate binding domain
KMEHGPNO_03311 5.9e-183 - - - Q - - - ubiE/COQ5 methyltransferase family
KMEHGPNO_03312 3.52e-135 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KMEHGPNO_03314 3.09e-139 tmrB - - S - - - AAA domain
KMEHGPNO_03315 1.83e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KMEHGPNO_03316 1.08e-144 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
KMEHGPNO_03317 0.0 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
KMEHGPNO_03318 3.73e-195 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
KMEHGPNO_03319 6.42e-147 ycgF - - E - - - Lysine exporter protein LysE YggA
KMEHGPNO_03320 3.7e-101 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
KMEHGPNO_03321 0.0 mdr - - EGP - - - the major facilitator superfamily
KMEHGPNO_03322 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
KMEHGPNO_03323 1.19e-232 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
KMEHGPNO_03324 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
KMEHGPNO_03325 3.86e-105 ycgB - - - - - - -
KMEHGPNO_03326 0.0 ycgA - - S - - - Membrane
KMEHGPNO_03327 3.26e-275 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
KMEHGPNO_03328 2.01e-210 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
KMEHGPNO_03329 2.1e-186 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
KMEHGPNO_03330 8.99e-293 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
KMEHGPNO_03331 4.82e-61 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
KMEHGPNO_03332 1.97e-259 - - - EGP - - - Uncharacterised MFS-type transporter YbfB
KMEHGPNO_03333 7.75e-278 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
KMEHGPNO_03334 2.96e-245 yceH - - P - - - Belongs to the TelA family
KMEHGPNO_03335 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
KMEHGPNO_03336 4.1e-176 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
KMEHGPNO_03337 4.97e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
KMEHGPNO_03338 8.9e-137 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
KMEHGPNO_03339 2.64e-141 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
KMEHGPNO_03340 3.44e-237 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KMEHGPNO_03341 4.63e-173 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
KMEHGPNO_03342 2.32e-169 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
KMEHGPNO_03343 1.95e-221 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
KMEHGPNO_03344 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
KMEHGPNO_03345 5.63e-179 - 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
KMEHGPNO_03346 1.16e-247 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
KMEHGPNO_03347 4.4e-122 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
KMEHGPNO_03348 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
KMEHGPNO_03349 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
KMEHGPNO_03350 1.35e-241 ycdA - - S - - - Domain of unknown function (DUF5105)
KMEHGPNO_03351 1.95e-221 yccK - - C - - - Aldo keto reductase
KMEHGPNO_03352 1.8e-253 - - - CP ko:K09696 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
KMEHGPNO_03353 2.2e-170 natA 3.6.3.7 - CP ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
KMEHGPNO_03354 6.86e-163 natR - - T ko:K02477,ko:K11641 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
KMEHGPNO_03355 2.51e-212 natK 2.7.13.3 - T ko:K11640 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
KMEHGPNO_03356 1.01e-254 yccF - - K ko:K07039 - ko00000 SEC-C motif
KMEHGPNO_03357 2.31e-73 - - - S - - - RDD family
KMEHGPNO_03358 4e-147 - 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
KMEHGPNO_03359 1.69e-257 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
KMEHGPNO_03360 6.54e-132 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
KMEHGPNO_03361 1.24e-302 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
KMEHGPNO_03362 4.17e-260 ycbU - - E - - - Selenocysteine lyase
KMEHGPNO_03363 3.43e-154 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KMEHGPNO_03364 3.61e-158 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KMEHGPNO_03365 3.12e-38 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
KMEHGPNO_03366 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
KMEHGPNO_03367 2.7e-174 ycbR - - T - - - vWA found in TerF C terminus
KMEHGPNO_03368 2.13e-101 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
KMEHGPNO_03369 2.21e-76 ycbP - - S - - - Protein of unknown function (DUF2512)
KMEHGPNO_03370 2.87e-148 - - - S - - - ABC-2 family transporter protein
KMEHGPNO_03371 3.74e-213 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KMEHGPNO_03372 1.53e-214 ycbM - - T - - - Histidine kinase
KMEHGPNO_03373 2.24e-161 ycbL - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KMEHGPNO_03374 1.35e-213 eamA1 - - EG - - - spore germination
KMEHGPNO_03375 1.24e-32 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
KMEHGPNO_03376 7.09e-222 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
KMEHGPNO_03377 0.0 garD 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
KMEHGPNO_03378 7.68e-160 ycbG - - K ko:K05799 - ko00000,ko03000 FCD
KMEHGPNO_03379 0.0 gudD 4.2.1.40 - M ko:K01706 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
KMEHGPNO_03380 0.0 gudP - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
KMEHGPNO_03381 0.0 ycbD - - C ko:K22187 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KMEHGPNO_03382 4.1e-222 ycbC 4.2.1.41 - EM ko:K01707 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 5-dehydro-4-deoxyglucarate dehydratase activity
KMEHGPNO_03383 4.94e-217 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
KMEHGPNO_03384 2.05e-293 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KMEHGPNO_03385 8.78e-238 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
KMEHGPNO_03386 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
KMEHGPNO_03387 1.29e-233 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
KMEHGPNO_03388 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
KMEHGPNO_03389 1.03e-257 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
KMEHGPNO_03391 2.91e-165 - - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
KMEHGPNO_03392 3.02e-174 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KMEHGPNO_03393 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KMEHGPNO_03394 6.04e-273 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KMEHGPNO_03395 1.16e-244 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
KMEHGPNO_03396 0.0 - - - S ko:K06880 - ko00000,ko01000,ko01504 Erythromycin esterase
KMEHGPNO_03397 1.58e-59 ybfN - - - - - - -
KMEHGPNO_03398 2.06e-188 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
KMEHGPNO_03399 7.07e-112 ybfM - - S - - - SNARE associated Golgi protein
KMEHGPNO_03400 2.81e-123 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KMEHGPNO_03401 1.12e-213 - - - S - - - Alpha/beta hydrolase family
KMEHGPNO_03403 2.39e-228 mpr - - M - - - Belongs to the peptidase S1B family
KMEHGPNO_03404 7.62e-270 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KMEHGPNO_03405 7.39e-188 ybfI - - K - - - AraC-like ligand binding domain
KMEHGPNO_03406 2.5e-206 ybfH - - EG - - - EamA-like transporter family
KMEHGPNO_03407 2.9e-285 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
KMEHGPNO_03408 2.87e-216 ybfA - - K - - - FR47-like protein
KMEHGPNO_03409 1.02e-46 - - - S - - - Protein of unknown function (DUF2651)
KMEHGPNO_03410 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
KMEHGPNO_03411 8.15e-206 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
KMEHGPNO_03412 4.04e-55 - - - M - - - PFAM Glycosyl transferase family 2
KMEHGPNO_03413 0.0 ybeC - - E - - - amino acid
KMEHGPNO_03414 1.11e-54 ybyB - - - - - - -
KMEHGPNO_03415 4.43e-313 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
KMEHGPNO_03416 1.24e-191 ybxI 3.5.2.6 - V ko:K17838 ko01501,map01501 ko00000,ko00001,ko01000 beta-lactamase
KMEHGPNO_03417 6.92e-41 ybxH - - S - - - Family of unknown function (DUF5370)
KMEHGPNO_03418 5.46e-51 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
KMEHGPNO_03419 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
KMEHGPNO_03420 4.26e-272 ybdO - - S - - - Domain of unknown function (DUF4885)
KMEHGPNO_03421 2.79e-178 ybdM 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 Protein tyrosine kinase
KMEHGPNO_03423 1.08e-216 - - - T - - - His Kinase A (phospho-acceptor) domain
KMEHGPNO_03424 6.9e-158 - - - T ko:K02483 - ko00000,ko02022 Transcriptional regulatory protein, C terminal
KMEHGPNO_03425 3.83e-231 - - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KMEHGPNO_03426 9.98e-75 - - - - - - - -
KMEHGPNO_03427 3.65e-255 ybcL - - EGP ko:K08164 - ko00000,ko02000 COG2814 Arabinose efflux permease
KMEHGPNO_03428 9.45e-67 - - - K - - - Helix-turn-helix domain
KMEHGPNO_03429 3.6e-80 ybcI - - S - - - Uncharacterized conserved protein (DUF2294)
KMEHGPNO_03430 4.6e-63 - - - - - - - -
KMEHGPNO_03432 1.15e-119 ybcF - - P - - - carbonic anhydrase
KMEHGPNO_03433 0.0 ybcC - - S ko:K09822 - ko00000 Belongs to the UPF0753 family
KMEHGPNO_03434 0.0 ndhF 1.6.5.3 - CP ko:K05577 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
KMEHGPNO_03435 1.76e-125 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KMEHGPNO_03436 1.25e-152 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
KMEHGPNO_03437 1.61e-221 alkA 3.2.2.21 - L ko:K01247,ko:K13529 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KMEHGPNO_03438 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KMEHGPNO_03439 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KMEHGPNO_03440 3.55e-291 ybbR - - S - - - protein conserved in bacteria
KMEHGPNO_03441 5.43e-189 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KMEHGPNO_03442 1.11e-151 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
KMEHGPNO_03443 4.59e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
KMEHGPNO_03449 1.99e-99 ybbK - - S - - - Protein of unknown function (DUF523)
KMEHGPNO_03450 4.28e-112 ybbJ - - J - - - acetyltransferase
KMEHGPNO_03451 1.35e-209 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KMEHGPNO_03452 5.21e-192 ybbH - - K - - - transcriptional
KMEHGPNO_03453 6.98e-302 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KMEHGPNO_03454 0.0 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
KMEHGPNO_03455 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
KMEHGPNO_03456 2.33e-302 ybbC - - S - - - protein conserved in bacteria
KMEHGPNO_03457 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
KMEHGPNO_03458 5.12e-216 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
KMEHGPNO_03459 1.17e-225 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KMEHGPNO_03460 3.51e-228 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KMEHGPNO_03461 2.14e-164 ybbA - - S ko:K07017 - ko00000 Putative esterase
KMEHGPNO_03462 5.36e-203 ybaS - - S - - - Na -dependent transporter
KMEHGPNO_03463 0.0 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
KMEHGPNO_03464 1.56e-08 - - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
KMEHGPNO_03467 3.38e-225 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KMEHGPNO_03468 7.42e-112 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
KMEHGPNO_03469 4.84e-161 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
KMEHGPNO_03470 4.91e-109 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
KMEHGPNO_03471 1.34e-240 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KMEHGPNO_03472 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
KMEHGPNO_03473 2.95e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
KMEHGPNO_03474 2.14e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KMEHGPNO_03475 5.48e-31 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
KMEHGPNO_03476 3.55e-161 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KMEHGPNO_03477 3.2e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
KMEHGPNO_03478 3e-167 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
KMEHGPNO_03479 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KMEHGPNO_03480 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KMEHGPNO_03481 3.48e-189 ydjC - - S - - - Abhydrolase domain containing 18
KMEHGPNO_03482 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
KMEHGPNO_03483 1.51e-258 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
KMEHGPNO_03484 0.0 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
KMEHGPNO_03485 1.48e-221 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
KMEHGPNO_03486 1.08e-147 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
KMEHGPNO_03487 1.73e-226 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KMEHGPNO_03488 7.87e-166 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
KMEHGPNO_03489 5.98e-202 ydjI - - S - - - virion core protein (lumpy skin disease virus)
KMEHGPNO_03490 1.37e-248 - - - S - - - Ion transport 2 domain protein
KMEHGPNO_03491 0.0 iolT - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
KMEHGPNO_03492 2.88e-248 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
KMEHGPNO_03493 1.79e-84 ydjM - - M - - - Lytic transglycolase
KMEHGPNO_03494 2.81e-208 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
KMEHGPNO_03496 8.2e-48 ydjO - - S - - - Cold-inducible protein YdjO
KMEHGPNO_03497 2.43e-200 - - - I - - - Alpha/beta hydrolase family
KMEHGPNO_03498 9.69e-227 yeaA - - S - - - Protein of unknown function (DUF4003)
KMEHGPNO_03499 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
KMEHGPNO_03500 0.0 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
KMEHGPNO_03501 1.76e-198 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KMEHGPNO_03502 5.62e-226 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
KMEHGPNO_03503 6.46e-285 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
KMEHGPNO_03504 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
KMEHGPNO_03505 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
KMEHGPNO_03506 3.39e-115 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
KMEHGPNO_03507 2.7e-313 - - - S - - - Domain of unknown function (DUF4179)
KMEHGPNO_03508 9.81e-283 pbuG - - S ko:K06901 - ko00000,ko02000 permease
KMEHGPNO_03509 3.38e-164 yebC - - M - - - Membrane
KMEHGPNO_03511 1.08e-119 yebE - - S - - - UPF0316 protein
KMEHGPNO_03512 3.13e-38 yebG - - S - - - NETI protein
KMEHGPNO_03513 2.28e-108 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KMEHGPNO_03514 5.21e-275 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KMEHGPNO_03515 2.81e-314 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KMEHGPNO_03516 1.18e-167 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
KMEHGPNO_03517 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KMEHGPNO_03518 1.15e-167 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KMEHGPNO_03519 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KMEHGPNO_03520 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KMEHGPNO_03521 1.71e-240 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
KMEHGPNO_03522 3.62e-137 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KMEHGPNO_03523 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
KMEHGPNO_03524 7.74e-296 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
KMEHGPNO_03525 8.41e-91 - - - K - - - helix_turn_helix ASNC type
KMEHGPNO_03526 8.3e-292 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
KMEHGPNO_03527 3.45e-37 - - - S - - - Protein of unknown function (DUF2892)
KMEHGPNO_03528 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
KMEHGPNO_03529 9.58e-244 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
KMEHGPNO_03530 6.27e-67 yerC - - S - - - protein conserved in bacteria
KMEHGPNO_03531 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
KMEHGPNO_03533 1.1e-161 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
KMEHGPNO_03534 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
KMEHGPNO_03535 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KMEHGPNO_03536 5.07e-281 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
KMEHGPNO_03537 1.8e-252 yerI - - S - - - homoserine kinase type II (protein kinase fold)
KMEHGPNO_03538 2.29e-160 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
KMEHGPNO_03539 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KMEHGPNO_03540 7.37e-61 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KMEHGPNO_03541 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KMEHGPNO_03542 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KMEHGPNO_03543 2.23e-185 yerO - - K - - - Transcriptional regulator
KMEHGPNO_03544 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KMEHGPNO_03545 1.8e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KMEHGPNO_03546 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KMEHGPNO_03549 6.1e-13 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 asparagine synthase
KMEHGPNO_03555 5.28e-102 - - - V - - - ABC-type multidrug transport system, ATPase and permease
KMEHGPNO_03556 1.46e-113 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KMEHGPNO_03557 4.98e-196 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
KMEHGPNO_03558 1.35e-82 - 3.4.24.40 - CO ko:K01406 ko01503,map01503 ko00000,ko00001,ko01000,ko01002 amine dehydrogenase activity
KMEHGPNO_03559 1.53e-265 rapH - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Tetratricopeptide repeat
KMEHGPNO_03561 6.29e-162 yeeN - - K - - - transcriptional regulatory protein
KMEHGPNO_03563 3.32e-128 dhaR3 - - K ko:K16137 - ko00000,ko03000 Transcriptional regulator
KMEHGPNO_03564 7.91e-104 yesE - - S ko:K06893 - ko00000 SnoaL-like domain
KMEHGPNO_03565 4.1e-194 yesF - - GM - - - NAD(P)H-binding
KMEHGPNO_03566 3.8e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
KMEHGPNO_03567 2.31e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
KMEHGPNO_03568 1.04e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
KMEHGPNO_03569 1.14e-128 yesJ - - K - - - Acetyltransferase (GNAT) family
KMEHGPNO_03571 1.95e-132 yesL - - S - - - Protein of unknown function, DUF624
KMEHGPNO_03572 0.0 yesM 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KMEHGPNO_03573 7.38e-253 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
KMEHGPNO_03574 4.13e-314 yesO - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
KMEHGPNO_03575 2.02e-218 yesP - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KMEHGPNO_03576 1.31e-212 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KMEHGPNO_03577 3.8e-252 - 3.2.1.172 GH105 S ko:K15532 - ko00000,ko01000 Glycosyl Hydrolase Family 88
KMEHGPNO_03578 0.0 yesS - - K - - - Transcriptional regulator
KMEHGPNO_03579 3.68e-164 - - - E - - - GDSL-like Lipase/Acylhydrolase
KMEHGPNO_03580 4.53e-166 yesU - - S - - - Domain of unknown function (DUF1961)
KMEHGPNO_03581 4.02e-145 - - - S - - - Protein of unknown function, DUF624
KMEHGPNO_03582 0.0 - 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
KMEHGPNO_03583 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
KMEHGPNO_03584 9.13e-160 - - - E - - - GDSL-like Lipase/Acylhydrolase
KMEHGPNO_03585 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
KMEHGPNO_03586 0.0 yetA - - - - - - -
KMEHGPNO_03587 0.0 lplA - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
KMEHGPNO_03588 9.71e-226 lplB - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
KMEHGPNO_03589 7.85e-209 - - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KMEHGPNO_03590 0.0 - 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
KMEHGPNO_03591 3.66e-157 yetF - - S - - - membrane
KMEHGPNO_03592 1.9e-72 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
KMEHGPNO_03593 2.47e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KMEHGPNO_03594 6.13e-38 - - - - - - - -
KMEHGPNO_03595 4.37e-185 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KMEHGPNO_03596 1.55e-27 yezD - - S - - - Uncharacterized small protein (DUF2292)
KMEHGPNO_03597 5.15e-135 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
KMEHGPNO_03598 2.04e-08 - - - EG - - - EamA-like transporter family
KMEHGPNO_03599 1.86e-114 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
KMEHGPNO_03600 8.84e-266 yetM - - CH - - - FAD binding domain
KMEHGPNO_03601 5.64e-172 - - - M - - - Membrane
KMEHGPNO_03602 4.11e-251 yetN - - S - - - Protein of unknown function (DUF3900)
KMEHGPNO_03603 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
KMEHGPNO_03604 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
KMEHGPNO_03605 4.01e-186 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
KMEHGPNO_03606 1.37e-219 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
KMEHGPNO_03607 9.02e-228 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
KMEHGPNO_03608 2.84e-285 yfnE - - S - - - Glycosyltransferase like family 2
KMEHGPNO_03609 3.88e-242 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
KMEHGPNO_03610 7.24e-267 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
KMEHGPNO_03611 2.49e-166 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
KMEHGPNO_03612 2.4e-312 yfnA - - E ko:K03294 - ko00000 amino acid
KMEHGPNO_03613 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KMEHGPNO_03614 5.14e-161 yfmS - - NT - - - chemotaxis protein
KMEHGPNO_03615 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KMEHGPNO_03616 3.61e-96 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
KMEHGPNO_03617 3.54e-90 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
KMEHGPNO_03618 2.42e-263 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
KMEHGPNO_03619 4.96e-64 - - - O - - - Subtilase family
KMEHGPNO_03620 9.1e-23 - - - - - - - -
KMEHGPNO_03622 3.95e-74 - - - - - - - -
KMEHGPNO_03623 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KMEHGPNO_03624 4.19e-263 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
KMEHGPNO_03625 3.75e-98 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
KMEHGPNO_03626 2.72e-238 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
KMEHGPNO_03627 1.4e-192 fhuC 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
KMEHGPNO_03628 2.1e-223 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KMEHGPNO_03629 8.17e-221 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KMEHGPNO_03630 1.94e-219 yfmC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
KMEHGPNO_03631 1.06e-31 - - - S - - - Protein of unknown function (DUF3212)
KMEHGPNO_03632 1.71e-76 yflT - - S - - - Heat induced stress protein YflT
KMEHGPNO_03633 2.45e-307 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
KMEHGPNO_03634 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
KMEHGPNO_03635 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
KMEHGPNO_03636 2.68e-152 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
KMEHGPNO_03637 9.78e-231 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
KMEHGPNO_03638 7.59e-288 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
KMEHGPNO_03639 1.7e-192 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
KMEHGPNO_03640 1.95e-275 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KMEHGPNO_03641 2.97e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
KMEHGPNO_03642 2.31e-155 yflK - - S - - - protein conserved in bacteria
KMEHGPNO_03643 3.16e-25 yflJ - - S - - - Protein of unknown function (DUF2639)
KMEHGPNO_03644 6.9e-27 yflI - - - - - - -
KMEHGPNO_03645 1.73e-64 yflH - - S - - - Protein of unknown function (DUF3243)
KMEHGPNO_03646 1.14e-178 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
KMEHGPNO_03647 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
KMEHGPNO_03648 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
KMEHGPNO_03649 1.89e-87 ydhN1 - - S - - - Domain of unknown function (DUF1992)
KMEHGPNO_03650 0.0 yflA - - E ko:K03310 - ko00000 Sodium alanine symporter
KMEHGPNO_03651 3.63e-248 yfkT - - E ko:K06309 - ko00000 Spore germination protein
KMEHGPNO_03653 2.66e-270 yfkR - - S ko:K06297,ko:K06308 - ko00000 spore germination
KMEHGPNO_03654 0.0 yfkQ - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
KMEHGPNO_03655 0.0 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KMEHGPNO_03656 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
KMEHGPNO_03657 1.24e-172 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
KMEHGPNO_03658 6.16e-160 frp - - C - - - nitroreductase
KMEHGPNO_03659 0.0 yfkN 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
KMEHGPNO_03660 3.17e-113 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
KMEHGPNO_03661 6.21e-266 ydiN3 - - EGP - - - COG0477 Permeases of the major facilitator superfamily
KMEHGPNO_03662 5.99e-41 yfkK - - S - - - Belongs to the UPF0435 family
KMEHGPNO_03663 2.14e-110 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KMEHGPNO_03664 1.03e-66 yfkI - - S - - - gas vesicle protein
KMEHGPNO_03665 9.64e-184 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
KMEHGPNO_03666 1.64e-12 - - - - - - - -
KMEHGPNO_03667 1.9e-278 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
KMEHGPNO_03668 1.34e-235 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
KMEHGPNO_03669 3.69e-189 yfkD - - S - - - YfkD-like protein
KMEHGPNO_03670 4.44e-191 yfkC - - M - - - Mechanosensitive ion channel
KMEHGPNO_03671 1.76e-283 yfkA - - S - - - YfkB-like domain
KMEHGPNO_03672 3.26e-36 yfjT - - - - - - -
KMEHGPNO_03673 7.24e-198 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
KMEHGPNO_03674 1.73e-187 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
KMEHGPNO_03675 7.8e-237 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
KMEHGPNO_03676 3.22e-213 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KMEHGPNO_03677 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KMEHGPNO_03678 2.72e-56 - - - S - - - YfzA-like protein
KMEHGPNO_03679 1.92e-240 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KMEHGPNO_03680 9.55e-111 yfjM - - S - - - Psort location Cytoplasmic, score
KMEHGPNO_03681 1.36e-244 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KMEHGPNO_03682 1.59e-243 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KMEHGPNO_03683 6.07e-258 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KMEHGPNO_03684 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KMEHGPNO_03685 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
KMEHGPNO_03686 8.16e-36 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
KMEHGPNO_03687 7.42e-75 yfjF - - S ko:K09771 - ko00000,ko02000 UPF0060 membrane protein
KMEHGPNO_03688 2.16e-100 - - - S - - - Family of unknown function (DUF5381)
KMEHGPNO_03689 1.49e-131 yfjD - - S - - - Family of unknown function (DUF5381)
KMEHGPNO_03690 2.5e-185 yfjC - - - - - - -
KMEHGPNO_03691 1.31e-268 yfjB - - - - - - -
KMEHGPNO_03692 5.59e-61 yfjA - - S - - - Belongs to the WXG100 family
KMEHGPNO_03695 9.67e-25 - - - S - - - protein conserved in bacteria
KMEHGPNO_03697 1.77e-88 - - - S - - - LXG domain of WXG superfamily
KMEHGPNO_03700 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
KMEHGPNO_03701 5.03e-180 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
KMEHGPNO_03702 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KMEHGPNO_03703 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
KMEHGPNO_03704 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
KMEHGPNO_03705 2.01e-84 yfiD3 - - S - - - DoxX
KMEHGPNO_03706 2.85e-206 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
KMEHGPNO_03707 3.4e-239 baeS - - T - - - Histidine kinase
KMEHGPNO_03708 8.27e-144 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
KMEHGPNO_03709 3.75e-215 drrA - - V ko:K01990,ko:K09695 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
KMEHGPNO_03710 3.43e-263 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
KMEHGPNO_03711 1.4e-261 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
KMEHGPNO_03712 5.42e-128 padR - - K - - - transcriptional
KMEHGPNO_03713 7.87e-128 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
KMEHGPNO_03714 2.2e-251 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
KMEHGPNO_03715 4.18e-141 yfiR - - K - - - Transcriptional regulator
KMEHGPNO_03716 4.81e-276 yfiS - - EGP - - - Major facilitator superfamily
KMEHGPNO_03717 2.7e-126 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
KMEHGPNO_03718 0.0 yfiU - - EGP - - - the major facilitator superfamily
KMEHGPNO_03719 2.11e-103 yfiV - - K - - - transcriptional
KMEHGPNO_03720 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KMEHGPNO_03721 3.83e-231 yfiY - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
KMEHGPNO_03722 8.91e-225 yfiZ - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KMEHGPNO_03723 7.36e-229 yfhA - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KMEHGPNO_03724 3.62e-213 yfhB - - S - - - PhzF family
KMEHGPNO_03725 2.87e-138 yfhC - - C - - - nitroreductase
KMEHGPNO_03726 8.86e-35 yfhD - - S - - - YfhD-like protein
KMEHGPNO_03728 1.54e-219 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
KMEHGPNO_03729 5.39e-180 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
KMEHGPNO_03730 4.58e-69 yfhH - - S - - - Protein of unknown function (DUF1811)
KMEHGPNO_03732 4.94e-268 yfhI - - EGP - - - -transporter
KMEHGPNO_03733 2.25e-27 sspK - - S ko:K06428 - ko00000 reproduction
KMEHGPNO_03734 8.95e-60 yfhJ - - S - - - WVELL protein
KMEHGPNO_03735 1.91e-114 yfhK - - T - - - Bacterial SH3 domain homologues
KMEHGPNO_03736 6.3e-66 yfhL - - S - - - SdpI/YhfL protein family
KMEHGPNO_03737 6.53e-217 yfhM 3.8.1.5 - S ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Alpha beta hydrolase
KMEHGPNO_03738 3.43e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
KMEHGPNO_03739 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
KMEHGPNO_03740 2.07e-236 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
KMEHGPNO_03741 1.99e-266 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
KMEHGPNO_03742 1.73e-48 yfhS - - - - - - -
KMEHGPNO_03743 3.13e-172 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KMEHGPNO_03744 2.35e-14 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
KMEHGPNO_03745 8.19e-49 ygaB - - S - - - YgaB-like protein
KMEHGPNO_03746 8.1e-136 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
KMEHGPNO_03747 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
KMEHGPNO_03748 1.87e-238 ygaE - - S - - - Membrane
KMEHGPNO_03749 3.26e-312 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
KMEHGPNO_03750 5.66e-111 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
KMEHGPNO_03751 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
KMEHGPNO_03752 3.38e-73 ygzB - - S - - - UPF0295 protein
KMEHGPNO_03753 8.23e-215 ygxA - - S - - - Nucleotidyltransferase-like
KMEHGPNO_03754 7.88e-119 - - - M - - - Glycosyltransferase like family
KMEHGPNO_03755 5.8e-156 - - - H - - - Methionine biosynthesis protein MetW
KMEHGPNO_03756 2.03e-246 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
KMEHGPNO_03757 3.14e-274 - - - H - - - N-terminal domain of galactosyltransferase
KMEHGPNO_03759 2.78e-124 ynaD - - J - - - Acetyltransferase (GNAT) domain
KMEHGPNO_03760 5.66e-94 - - - S - - - CAAX protease self-immunity
KMEHGPNO_03761 2.5e-109 - - - E - - - phosphoribosylanthranilate isomerase activity
KMEHGPNO_03762 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
KMEHGPNO_03763 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
KMEHGPNO_03764 1.23e-275 xylR - - GK - - - ROK family
KMEHGPNO_03765 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
KMEHGPNO_03766 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
KMEHGPNO_03767 2.92e-144 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
KMEHGPNO_03768 0.0 - - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
KMEHGPNO_03769 5.06e-280 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KMEHGPNO_03770 3.51e-101 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
KMEHGPNO_03773 7.57e-208 - - - S - - - Thymidylate synthase
KMEHGPNO_03775 2.11e-170 - - - S - - - Domain of unknown function, YrpD
KMEHGPNO_03778 1.96e-33 tatA - - U ko:K03116,ko:K03117,ko:K03646 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02000,ko02044 protein secretion
KMEHGPNO_03779 8.58e-94 - - - - - - - -
KMEHGPNO_03780 1.81e-103 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
KMEHGPNO_03783 0.0 yndD1 - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
KMEHGPNO_03784 1.95e-250 yndE7 - - U ko:K06311 - ko00000,ko02000 Spore germination
KMEHGPNO_03785 9.89e-283 - - - S ko:K06293,ko:K06312 - ko00000 Spore germination protein
KMEHGPNO_03786 1.63e-192 yndG - - S - - - DoxX-like family
KMEHGPNO_03787 6.98e-149 - - - S - - - Domain of unknown function (DUF4166)
KMEHGPNO_03788 0.0 yndJ - - S - - - YndJ-like protein
KMEHGPNO_03790 2.68e-174 yndL - - S - - - Replication protein
KMEHGPNO_03791 3.79e-96 yndM - - S - - - Protein of unknown function (DUF2512)
KMEHGPNO_03792 1.43e-100 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
KMEHGPNO_03793 7.22e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KMEHGPNO_03794 8.5e-65 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
KMEHGPNO_03795 2.29e-144 yneB - - L - - - resolvase
KMEHGPNO_03796 1.15e-43 ynzC - - S - - - UPF0291 protein
KMEHGPNO_03797 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KMEHGPNO_03798 2.18e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
KMEHGPNO_03799 4.36e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
KMEHGPNO_03800 4.59e-21 ynzD - - S - - - Spo0E like sporulation regulatory protein
KMEHGPNO_03801 1.18e-164 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
KMEHGPNO_03802 2.12e-77 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
KMEHGPNO_03803 5.07e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
KMEHGPNO_03804 2.79e-97 yneK - - S - - - Protein of unknown function (DUF2621)
KMEHGPNO_03805 5.77e-85 cotM - - O ko:K06335 - ko00000 Spore coat protein
KMEHGPNO_03806 5.65e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
KMEHGPNO_03807 3.27e-21 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
KMEHGPNO_03808 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KMEHGPNO_03809 7.25e-118 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KMEHGPNO_03810 9.26e-10 - - - S - - - Fur-regulated basic protein B
KMEHGPNO_03812 6.62e-48 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
KMEHGPNO_03813 4.02e-95 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
KMEHGPNO_03814 2.02e-40 yneQ - - - - - - -
KMEHGPNO_03815 8.97e-65 yneR - - S - - - Belongs to the HesB IscA family
KMEHGPNO_03816 5.48e-122 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KMEHGPNO_03817 1.41e-89 yneT - - S ko:K06929 - ko00000 CoA-binding protein
KMEHGPNO_03818 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KMEHGPNO_03819 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KMEHGPNO_03820 1.82e-18 - - - - - - - -
KMEHGPNO_03821 8.74e-75 ynfC - - - - - - -
KMEHGPNO_03822 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
KMEHGPNO_03823 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
KMEHGPNO_03825 1.67e-315 ynfF 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
KMEHGPNO_03826 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
KMEHGPNO_03827 1.72e-103 yngA - - S - - - membrane
KMEHGPNO_03828 6.45e-209 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
KMEHGPNO_03829 2.01e-134 yngC - - S - - - membrane-associated protein
KMEHGPNO_03830 3.51e-294 yngD - - S ko:K07097 - ko00000 phosphohydrolase (DHH superfamily)
KMEHGPNO_03831 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
KMEHGPNO_03832 7.04e-174 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
KMEHGPNO_03833 9.56e-212 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
KMEHGPNO_03834 8.37e-42 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
KMEHGPNO_03835 1.87e-316 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
KMEHGPNO_03836 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KMEHGPNO_03837 8.86e-267 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
KMEHGPNO_03838 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
KMEHGPNO_03839 1.01e-82 yngL - - S - - - Protein of unknown function (DUF1360)
KMEHGPNO_03840 0.0 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
KMEHGPNO_03841 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KMEHGPNO_03842 4.31e-181 pdaB - - G - - - Polysaccharide deacetylase
KMEHGPNO_03843 5.95e-133 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
KMEHGPNO_03844 1.04e-122 gerD - - - ko:K06294 - ko00000 -
KMEHGPNO_03845 1.1e-255 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
KMEHGPNO_03846 9.05e-170 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
KMEHGPNO_03847 1.47e-90 ybaK - - S - - - Protein of unknown function (DUF2521)
KMEHGPNO_03848 4.15e-184 ybaJ - - Q - - - Methyltransferase domain
KMEHGPNO_03849 4.28e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
KMEHGPNO_03850 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KMEHGPNO_03851 4.33e-182 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KMEHGPNO_03852 1.6e-177 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KMEHGPNO_03853 1.1e-196 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KMEHGPNO_03854 7.5e-200 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KMEHGPNO_03855 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
KMEHGPNO_03856 7.01e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KMEHGPNO_03857 3.24e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KMEHGPNO_03858 1.09e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KMEHGPNO_03859 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
KMEHGPNO_03860 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KMEHGPNO_03861 2.32e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
KMEHGPNO_03862 2.51e-157 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KMEHGPNO_03863 5.7e-298 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KMEHGPNO_03864 7.32e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
KMEHGPNO_03865 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
KMEHGPNO_03866 9.16e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KMEHGPNO_03867 2.89e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KMEHGPNO_03868 4.47e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KMEHGPNO_03869 3.11e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KMEHGPNO_03870 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KMEHGPNO_03871 7.72e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KMEHGPNO_03872 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KMEHGPNO_03873 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KMEHGPNO_03874 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KMEHGPNO_03875 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
KMEHGPNO_03876 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KMEHGPNO_03877 1.69e-151 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KMEHGPNO_03878 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KMEHGPNO_03879 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KMEHGPNO_03880 2.72e-200 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KMEHGPNO_03881 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KMEHGPNO_03882 7.98e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
KMEHGPNO_03883 7.2e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KMEHGPNO_03884 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
KMEHGPNO_03885 2.59e-230 ybaC - - S - - - Alpha/beta hydrolase family
KMEHGPNO_03886 2.01e-287 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KMEHGPNO_03887 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KMEHGPNO_03888 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KMEHGPNO_03889 6.67e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KMEHGPNO_03890 1.99e-44 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
KMEHGPNO_03891 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KMEHGPNO_03892 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KMEHGPNO_03893 5.1e-140 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
KMEHGPNO_03894 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KMEHGPNO_03895 4.03e-104 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KMEHGPNO_03896 1.82e-162 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KMEHGPNO_03897 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KMEHGPNO_03898 1.37e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
KMEHGPNO_03899 2.65e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KMEHGPNO_03900 3.27e-149 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
KMEHGPNO_03901 3.31e-114 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
KMEHGPNO_03902 3.52e-173 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KMEHGPNO_03903 3.52e-96 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KMEHGPNO_03904 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
KMEHGPNO_03905 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
KMEHGPNO_03906 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KMEHGPNO_03907 6.35e-113 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
KMEHGPNO_03908 4.29e-161 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
KMEHGPNO_03909 2.57e-252 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
KMEHGPNO_03910 3.8e-251 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
KMEHGPNO_03911 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KMEHGPNO_03912 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
KMEHGPNO_03913 7.74e-257 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
KMEHGPNO_03914 2.36e-74 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
KMEHGPNO_03915 8.72e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
KMEHGPNO_03916 2.21e-42 csfB - - S - - - Inhibitor of sigma-G Gin
KMEHGPNO_03917 1.82e-130 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
KMEHGPNO_03918 8.37e-259 yaaN - - P - - - Belongs to the TelA family
KMEHGPNO_03919 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
KMEHGPNO_03920 1.63e-146 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KMEHGPNO_03921 1.02e-72 yaaQ - - S - - - protein conserved in bacteria
KMEHGPNO_03922 1.26e-95 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
KMEHGPNO_03923 1.15e-234 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
KMEHGPNO_03924 5.2e-188 yaaT - - S - - - stage 0 sporulation protein
KMEHGPNO_03925 1.53e-56 yabA - - L - - - Involved in initiation control of chromosome replication
KMEHGPNO_03926 1.63e-177 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
KMEHGPNO_03927 1.2e-64 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
KMEHGPNO_03928 2.95e-207 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KMEHGPNO_03929 1.51e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
KMEHGPNO_03930 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KMEHGPNO_03931 5.9e-184 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
KMEHGPNO_03932 4.1e-278 yabE - - T - - - protein conserved in bacteria
KMEHGPNO_03933 2.03e-125 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KMEHGPNO_03934 4.14e-198 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KMEHGPNO_03935 1.11e-198 yabG - - S ko:K06436 - ko00000 peptidase
KMEHGPNO_03936 5.32e-53 veg - - S - - - protein conserved in bacteria
KMEHGPNO_03937 3.96e-37 sspF - - S ko:K06423 - ko00000 DNA topological change
KMEHGPNO_03938 2.34e-207 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KMEHGPNO_03939 4.66e-196 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
KMEHGPNO_03940 3.45e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
KMEHGPNO_03941 2.45e-63 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
KMEHGPNO_03942 1.49e-308 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KMEHGPNO_03943 1.22e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KMEHGPNO_03944 2.41e-135 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KMEHGPNO_03945 2.03e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KMEHGPNO_03946 5.24e-53 yabK - - S - - - Peptide ABC transporter permease
KMEHGPNO_03947 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KMEHGPNO_03948 5.88e-121 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
KMEHGPNO_03949 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KMEHGPNO_03950 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
KMEHGPNO_03951 4.22e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
KMEHGPNO_03952 1.91e-66 yabP - - S - - - Sporulation protein YabP
KMEHGPNO_03953 1.49e-137 yabQ - - S - - - spore cortex biosynthesis protein
KMEHGPNO_03954 5.94e-75 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
KMEHGPNO_03955 2.49e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
KMEHGPNO_03958 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
KMEHGPNO_03959 5.61e-168 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
KMEHGPNO_03960 1.15e-234 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
KMEHGPNO_03961 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KMEHGPNO_03962 4.82e-121 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
KMEHGPNO_03963 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KMEHGPNO_03964 6.92e-189 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KMEHGPNO_03965 9.54e-208 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KMEHGPNO_03966 1.4e-203 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
KMEHGPNO_03967 1.54e-217 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
KMEHGPNO_03968 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KMEHGPNO_03969 5.98e-137 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
KMEHGPNO_03970 1.79e-213 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
KMEHGPNO_03971 3.32e-205 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KMEHGPNO_03972 3.8e-80 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KMEHGPNO_03973 4.56e-115 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KMEHGPNO_03974 3.02e-40 yazB - - K - - - transcriptional
KMEHGPNO_03975 1.59e-243 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KMEHGPNO_03976 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
KMEHGPNO_03977 3.19e-69 - - - V - - - HNH endonuclease
KMEHGPNO_03978 2.55e-90 yokH - - G - - - SMI1 / KNR4 family
KMEHGPNO_03979 6.17e-20 - - - S - - - SMI1 / KNR4 family
KMEHGPNO_03980 1.12e-38 - - - S - - - SMI1 / KNR4 family
KMEHGPNO_03981 3.76e-69 - - - S - - - Immunity protein 50
KMEHGPNO_03982 3.26e-249 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
KMEHGPNO_03983 1.71e-104 - - - T - - - COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
KMEHGPNO_03984 8.77e-192 - 1.1.1.219 - M ko:K00091 - ko00000,ko01000 NAD dependent epimerase dehydratase family
KMEHGPNO_03987 3.24e-117 - - - S - - - Tetratricopeptide repeat
KMEHGPNO_03989 3.69e-223 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
KMEHGPNO_03990 2.17e-99 yvbU - - K - - - Transcriptional regulator
KMEHGPNO_03991 5.29e-76 - - - S - - - Flavodoxin-like fold
KMEHGPNO_03992 2.92e-197 - 1.8.5.5 - C ko:K08352 ko00920,ko01120,map00920,map01120 ko00000,ko00001,ko01000,ko02000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KMEHGPNO_03993 3.07e-96 - - - P ko:K03449 - ko00000,ko02000 transporter
KMEHGPNO_03994 2.61e-265 - - - EGP ko:K18926 - ko00000,ko00002,ko02000 Major Facilitator Superfamily
KMEHGPNO_03995 5.98e-92 - 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
KMEHGPNO_03996 1.8e-202 ydhE - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
KMEHGPNO_03997 1.14e-197 yybE - - K - - - Transcriptional regulator
KMEHGPNO_03998 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
KMEHGPNO_04000 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
KMEHGPNO_04001 2.93e-279 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aspartate tyrosine aromatic aminotransferase
KMEHGPNO_04002 9.72e-183 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
KMEHGPNO_04003 2.4e-194 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KMEHGPNO_04004 6.03e-78 yuxO - - Q - - - Thioesterase superfamily
KMEHGPNO_04005 8.53e-245 - - - S ko:K12270 - ko00000,ko02044 Accessory Sec secretory system ASP3
KMEHGPNO_04006 0.0 - - - S ko:K12269 - ko00000,ko02044 Accessory Sec system GspB-transporter
KMEHGPNO_04007 0.0 asp1 - - S ko:K12268 - ko00000,ko02044 Accessory Sec system protein Asp1
KMEHGPNO_04008 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
KMEHGPNO_04009 0.0 tagE6 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
KMEHGPNO_04010 6.66e-176 comD 2.7.13.3 - T ko:K07706,ko:K12294 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
KMEHGPNO_04011 9.6e-156 fasA - - T ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Response regulator of the LytR AlgR family
KMEHGPNO_04012 5.44e-109 gpo 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
KMEHGPNO_04013 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KMEHGPNO_04014 1.57e-54 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KMEHGPNO_04015 2.14e-232 yaaC - - S - - - YaaC-like Protein
KMEHGPNO_04016 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
KMEHGPNO_04017 2.16e-315 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
KMEHGPNO_04018 3.7e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
KMEHGPNO_04019 1.66e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KMEHGPNO_04020 9.79e-296 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KMEHGPNO_04022 3.72e-159 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
KMEHGPNO_04023 5.73e-149 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
KMEHGPNO_04024 5.18e-276 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
KMEHGPNO_04025 3.26e-124 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
KMEHGPNO_04026 1.05e-108 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KMEHGPNO_04027 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KMEHGPNO_04028 8.75e-55 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KMEHGPNO_04029 8.53e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KMEHGPNO_04030 1.55e-42 yaaL - - S - - - Protein of unknown function (DUF2508)
KMEHGPNO_04031 5.3e-49 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
KMEHGPNO_04032 0.0 - - - Q ko:K15665 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KMEHGPNO_04033 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KMEHGPNO_04034 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KMEHGPNO_04035 2.02e-168 glnQ 3.6.3.21 - E ko:K02028,ko:K17076 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC-type polar amino acid transport system, ATPase component
KMEHGPNO_04036 1.81e-130 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
KMEHGPNO_04037 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
KMEHGPNO_04038 1.72e-75 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)