ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
HMMFCFNL_00001 2.52e-122 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
HMMFCFNL_00002 1.4e-121 - - - M - - - FR47-like protein
HMMFCFNL_00003 4.54e-258 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
HMMFCFNL_00004 1.68e-109 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
HMMFCFNL_00005 1.95e-109 yuaE - - S - - - DinB superfamily
HMMFCFNL_00006 1.66e-136 yuaD - - - - - - -
HMMFCFNL_00007 2.46e-291 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
HMMFCFNL_00008 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HMMFCFNL_00009 2.39e-121 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
HMMFCFNL_00010 5.83e-118 yuaB - - - - - - -
HMMFCFNL_00011 1.06e-156 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
HMMFCFNL_00012 1.07e-300 - - - P ko:K03498 - ko00000,ko02000 Potassium
HMMFCFNL_00013 3.31e-52 yubF - - S - - - yiaA/B two helix domain
HMMFCFNL_00014 3.09e-195 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HMMFCFNL_00015 0.0 yubD - - P - - - Major Facilitator Superfamily
HMMFCFNL_00016 2.29e-112 cdoA 1.13.11.20 - S ko:K00456 ko00270,ko00430,ko01100,map00270,map00430,map01100 ko00000,ko00001,ko01000 Cysteine dioxygenase type I
HMMFCFNL_00018 1.73e-182 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HMMFCFNL_00019 8.95e-255 yubA - - S - - - transporter activity
HMMFCFNL_00020 7.48e-235 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
HMMFCFNL_00021 9.8e-317 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Belongs to the rhamnose isomerase family
HMMFCFNL_00022 2.86e-72 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
HMMFCFNL_00023 0.0 rhaB 2.7.1.5 - G ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HMMFCFNL_00024 5.79e-172 yulB - - K ko:K02530,ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
HMMFCFNL_00025 0.0 yuxG - - IQ - - - Class II Aldolase and Adducin N-terminal domain
HMMFCFNL_00026 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HMMFCFNL_00027 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HMMFCFNL_00028 1.81e-299 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HMMFCFNL_00029 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HMMFCFNL_00030 6.15e-181 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
HMMFCFNL_00031 5e-48 - - - - - - - -
HMMFCFNL_00032 3.63e-95 yugU - - S - - - Uncharacterised protein family UPF0047
HMMFCFNL_00033 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
HMMFCFNL_00034 8.8e-301 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
HMMFCFNL_00035 4.8e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
HMMFCFNL_00036 1.58e-50 - - - - - - - -
HMMFCFNL_00037 5.01e-69 mstX - - S - - - Membrane-integrating protein Mistic
HMMFCFNL_00038 3.56e-233 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
HMMFCFNL_00039 4.22e-95 yugN - - S - - - YugN-like family
HMMFCFNL_00041 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
HMMFCFNL_00042 9.22e-290 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
HMMFCFNL_00043 2.85e-287 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
HMMFCFNL_00044 2.21e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
HMMFCFNL_00045 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
HMMFCFNL_00046 6.34e-254 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
HMMFCFNL_00047 6.74e-112 alaR - - K - - - Transcriptional regulator
HMMFCFNL_00048 2.72e-198 yugF - - I - - - Hydrolase
HMMFCFNL_00049 8.84e-52 yugE - - S - - - Domain of unknown function (DUF1871)
HMMFCFNL_00050 2.85e-287 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HMMFCFNL_00051 3.04e-296 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HMMFCFNL_00052 2.49e-91 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
HMMFCFNL_00053 1.71e-149 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
HMMFCFNL_00055 4.61e-244 yuxJ - - EGP - - - Major facilitator superfamily
HMMFCFNL_00056 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
HMMFCFNL_00057 3.31e-98 yuxK - - S - - - protein conserved in bacteria
HMMFCFNL_00058 4.19e-113 yufK - - S - - - Family of unknown function (DUF5366)
HMMFCFNL_00059 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
HMMFCFNL_00060 3.26e-162 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
HMMFCFNL_00061 5.28e-246 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
HMMFCFNL_00062 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HMMFCFNL_00063 1.29e-236 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HMMFCFNL_00064 2.43e-215 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HMMFCFNL_00065 7.99e-309 malP - - C ko:K11616 ko02020,map02020 ko00000,ko00001 COG3493 Na citrate symporter
HMMFCFNL_00066 1.73e-22 - - - - - - - -
HMMFCFNL_00067 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HMMFCFNL_00068 7.66e-91 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HMMFCFNL_00069 1.72e-66 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HMMFCFNL_00070 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HMMFCFNL_00071 2.12e-102 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HMMFCFNL_00072 2.23e-51 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HMMFCFNL_00073 5.97e-79 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
HMMFCFNL_00074 7.81e-83 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
HMMFCFNL_00075 2.06e-150 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HMMFCFNL_00076 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HMMFCFNL_00078 5.71e-209 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Polyprenyl synthetase
HMMFCFNL_00079 6.29e-10 - - - S - - - DegQ (SacQ) family
HMMFCFNL_00080 8.73e-09 yuzC - - - - - - -
HMMFCFNL_00081 2.92e-298 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
HMMFCFNL_00082 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HMMFCFNL_00083 7.71e-133 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
HMMFCFNL_00084 3.64e-86 - - - S - - - Protein of unknown function (DUF1694)
HMMFCFNL_00085 1.63e-52 yueH - - S - - - YueH-like protein
HMMFCFNL_00086 1.19e-41 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
HMMFCFNL_00087 1.35e-244 yueF - - S - - - transporter activity
HMMFCFNL_00088 1.1e-90 - - - S - - - Protein of unknown function (DUF2283)
HMMFCFNL_00089 8.4e-33 - - - S - - - Protein of unknown function (DUF2642)
HMMFCFNL_00090 1.91e-125 yueE - - S ko:K06950 - ko00000 phosphohydrolase
HMMFCFNL_00091 6.83e-168 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HMMFCFNL_00092 1.78e-96 yueC - - S - - - Family of unknown function (DUF5383)
HMMFCFNL_00093 0.0 yueB - - S - - - type VII secretion protein EsaA
HMMFCFNL_00094 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HMMFCFNL_00095 8.62e-271 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
HMMFCFNL_00096 1.93e-54 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
HMMFCFNL_00097 3.93e-60 yukE - - S - - - Belongs to the WXG100 family
HMMFCFNL_00098 2.33e-289 yukF - - QT - - - Transcriptional regulator
HMMFCFNL_00099 4.02e-262 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
HMMFCFNL_00100 4.88e-168 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
HMMFCFNL_00101 2.02e-47 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
HMMFCFNL_00102 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMMFCFNL_00103 3.83e-229 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
HMMFCFNL_00104 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
HMMFCFNL_00105 7.03e-289 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
HMMFCFNL_00106 5.83e-178 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
HMMFCFNL_00107 1.27e-212 eSD - - S ko:K07017 - ko00000 Putative esterase
HMMFCFNL_00108 1.6e-155 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
HMMFCFNL_00109 7.98e-123 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
HMMFCFNL_00110 1.05e-278 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
HMMFCFNL_00111 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HMMFCFNL_00112 8.63e-102 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
HMMFCFNL_00113 1.5e-149 yuiC - - S - - - protein conserved in bacteria
HMMFCFNL_00114 9.78e-47 yuiB - - S - - - Putative membrane protein
HMMFCFNL_00115 4.16e-301 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HMMFCFNL_00116 1.16e-240 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
HMMFCFNL_00118 7.47e-234 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HMMFCFNL_00119 8.15e-149 paiB - - K ko:K07734 - ko00000,ko03000 Putative FMN-binding domain
HMMFCFNL_00120 3.98e-115 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HMMFCFNL_00121 6.81e-83 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
HMMFCFNL_00122 3.9e-208 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HMMFCFNL_00123 5.13e-269 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HMMFCFNL_00124 2.47e-52 yuzB - - S - - - Belongs to the UPF0349 family
HMMFCFNL_00125 1.12e-253 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HMMFCFNL_00126 1.56e-73 yuzD - - S - - - protein conserved in bacteria
HMMFCFNL_00127 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
HMMFCFNL_00128 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
HMMFCFNL_00129 2.57e-221 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HMMFCFNL_00130 3.97e-252 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HMMFCFNL_00131 2.76e-306 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
HMMFCFNL_00132 4.98e-252 yutH - - S - - - Spore coat protein
HMMFCFNL_00133 2.26e-101 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
HMMFCFNL_00134 3.69e-183 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HMMFCFNL_00135 1.96e-98 yutE - - S - - - Protein of unknown function DUF86
HMMFCFNL_00136 3.2e-63 yutD - - S - - - protein conserved in bacteria
HMMFCFNL_00137 1.34e-144 yutC - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HMMFCFNL_00138 1.37e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HMMFCFNL_00139 7.63e-252 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
HMMFCFNL_00140 3.49e-169 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
HMMFCFNL_00141 8.06e-64 yunC - - S - - - Domain of unknown function (DUF1805)
HMMFCFNL_00142 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HMMFCFNL_00143 6.51e-181 yunE - - S ko:K07090 - ko00000 membrane transporter protein
HMMFCFNL_00144 4.26e-220 yunF - - S - - - Protein of unknown function DUF72
HMMFCFNL_00145 3.06e-79 yunG - - - - - - -
HMMFCFNL_00146 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
HMMFCFNL_00147 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
HMMFCFNL_00148 2.2e-293 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 Permease family
HMMFCFNL_00149 3.18e-283 pbuX - - F ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
HMMFCFNL_00150 0.0 - 1.7.3.3, 4.1.1.97 - Q ko:K16838 ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
HMMFCFNL_00151 2.09e-72 pucM 3.5.2.17 - S ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
HMMFCFNL_00152 0.000154 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
HMMFCFNL_00153 2.42e-122 - 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03518 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
HMMFCFNL_00154 0.0 pucD 1.17.1.4 - C ko:K00087 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
HMMFCFNL_00155 1.74e-187 pucC 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03519 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
HMMFCFNL_00156 1.2e-140 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
HMMFCFNL_00157 8.74e-235 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HMMFCFNL_00158 1.65e-303 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
HMMFCFNL_00159 6.56e-292 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HMMFCFNL_00160 3.11e-216 bsn - - L - - - Ribonuclease
HMMFCFNL_00161 2.42e-262 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HMMFCFNL_00162 8.71e-175 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
HMMFCFNL_00163 9.57e-209 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
HMMFCFNL_00164 2.27e-215 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
HMMFCFNL_00165 3.54e-199 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HMMFCFNL_00166 4.07e-307 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
HMMFCFNL_00167 5.27e-235 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
HMMFCFNL_00168 1.2e-87 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
HMMFCFNL_00169 7.22e-262 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
HMMFCFNL_00171 3.35e-56 - - - - - - - -
HMMFCFNL_00172 5.06e-86 yurT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HMMFCFNL_00173 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
HMMFCFNL_00174 6.26e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
HMMFCFNL_00175 2.69e-297 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HMMFCFNL_00176 6.1e-312 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
HMMFCFNL_00177 4.46e-182 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HMMFCFNL_00178 1.56e-80 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HMMFCFNL_00179 5.86e-189 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
HMMFCFNL_00180 7.57e-125 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
HMMFCFNL_00181 2.15e-236 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HMMFCFNL_00182 1.53e-74 yusD - - S - - - SCP-2 sterol transfer family
HMMFCFNL_00183 8.14e-73 yusE - - CO - - - Thioredoxin
HMMFCFNL_00184 3.77e-97 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
HMMFCFNL_00185 7.34e-54 yusG - - S - - - Protein of unknown function (DUF2553)
HMMFCFNL_00186 5.91e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
HMMFCFNL_00187 1.01e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
HMMFCFNL_00188 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
HMMFCFNL_00189 1.34e-278 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
HMMFCFNL_00190 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
HMMFCFNL_00191 1.11e-13 - - - S - - - YuzL-like protein
HMMFCFNL_00192 2.84e-210 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
HMMFCFNL_00193 2.23e-54 - - - - - - - -
HMMFCFNL_00194 8.66e-70 yusN - - M - - - Coat F domain
HMMFCFNL_00195 6.35e-98 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
HMMFCFNL_00196 0.0 yusP - - P - - - Major facilitator superfamily
HMMFCFNL_00197 4.86e-84 yusQ - - S - - - Tautomerase enzyme
HMMFCFNL_00198 4.07e-137 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
HMMFCFNL_00199 8.42e-204 gltR - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
HMMFCFNL_00200 3.99e-53 yusU - - S - - - Protein of unknown function (DUF2573)
HMMFCFNL_00201 1.06e-196 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HMMFCFNL_00202 3.48e-88 - - - S - - - YusW-like protein
HMMFCFNL_00203 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
HMMFCFNL_00204 1.75e-193 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HMMFCFNL_00205 2.15e-104 fri - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
HMMFCFNL_00206 7.9e-305 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HMMFCFNL_00207 2.23e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HMMFCFNL_00208 2.77e-316 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HMMFCFNL_00209 3.06e-204 yuxN - - K - - - Transcriptional regulator
HMMFCFNL_00210 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HMMFCFNL_00211 4.48e-34 - - - S - - - Protein of unknown function (DUF3970)
HMMFCFNL_00212 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
HMMFCFNL_00213 3.94e-251 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
HMMFCFNL_00214 3.05e-243 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
HMMFCFNL_00215 4.46e-139 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HMMFCFNL_00216 4.06e-246 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HMMFCFNL_00217 7.65e-164 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
HMMFCFNL_00218 2.19e-176 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
HMMFCFNL_00219 4.05e-142 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
HMMFCFNL_00220 1.51e-82 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
HMMFCFNL_00221 6.23e-286 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
HMMFCFNL_00222 1.93e-131 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
HMMFCFNL_00223 1.22e-307 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HMMFCFNL_00224 1.56e-235 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HMMFCFNL_00225 2.98e-218 btuF - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
HMMFCFNL_00226 1.23e-180 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HMMFCFNL_00227 1.32e-219 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
HMMFCFNL_00228 0.0 yvrG - - T - - - Histidine kinase
HMMFCFNL_00229 1.1e-170 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HMMFCFNL_00230 5.07e-32 - - - - - - - -
HMMFCFNL_00231 7.02e-128 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
HMMFCFNL_00232 3.46e-26 - - - S - - - YvrJ protein family
HMMFCFNL_00233 1.86e-291 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
HMMFCFNL_00234 9.89e-86 yvrL - - S - - - Regulatory protein YrvL
HMMFCFNL_00235 3.36e-272 yvrN - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
HMMFCFNL_00236 3.82e-158 yvrO - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HMMFCFNL_00237 3.61e-231 - - - M ko:K02005 - ko00000 Efflux transporter rnd family, mfp subunit
HMMFCFNL_00238 2.92e-191 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HMMFCFNL_00239 4.78e-226 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HMMFCFNL_00240 1.72e-236 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HMMFCFNL_00241 3.65e-224 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HMMFCFNL_00242 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
HMMFCFNL_00243 9.37e-23 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
HMMFCFNL_00244 2.38e-109 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
HMMFCFNL_00245 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
HMMFCFNL_00246 6.98e-212 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
HMMFCFNL_00247 4.25e-175 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
HMMFCFNL_00248 5.83e-152 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
HMMFCFNL_00249 6.19e-201 yvgN - - S - - - reductase
HMMFCFNL_00250 7.97e-113 yvgO - - - - - - -
HMMFCFNL_00251 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
HMMFCFNL_00252 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HMMFCFNL_00253 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HMMFCFNL_00254 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
HMMFCFNL_00256 2.34e-139 yvgT - - S - - - membrane
HMMFCFNL_00257 5.7e-95 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
HMMFCFNL_00258 3.45e-137 bdbD - - O - - - Thioredoxin
HMMFCFNL_00259 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
HMMFCFNL_00260 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
HMMFCFNL_00261 3.66e-41 copZ - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Copper resistance protein CopZ
HMMFCFNL_00262 6.89e-65 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
HMMFCFNL_00263 2.83e-247 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
HMMFCFNL_00264 5.09e-154 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HMMFCFNL_00265 0.0 - - - S - - - Fusaric acid resistance protein-like
HMMFCFNL_00266 2.02e-97 yvaD - - S - - - Family of unknown function (DUF5360)
HMMFCFNL_00267 3.52e-71 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
HMMFCFNL_00268 5.77e-127 - - - K - - - Bacterial regulatory proteins, tetR family
HMMFCFNL_00269 3.96e-182 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
HMMFCFNL_00271 9.66e-242 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
HMMFCFNL_00272 3.84e-84 - - - S - - - Immunity protein 70
HMMFCFNL_00274 1.44e-140 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
HMMFCFNL_00275 2.18e-75 - - - S - - - Bacteriophage holin family
HMMFCFNL_00278 1.14e-75 - - - - - - - -
HMMFCFNL_00281 5.04e-62 - - - - - - - -
HMMFCFNL_00282 1.32e-306 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
HMMFCFNL_00283 1.02e-143 - - - S - - - Phage tail protein
HMMFCFNL_00284 3.89e-247 - - - S - - - peptidoglycan catabolic process
HMMFCFNL_00285 8.72e-224 - - - S - - - peptidoglycan catabolic process
HMMFCFNL_00286 8.27e-16 - - - - - - - -
HMMFCFNL_00287 1.58e-36 - - - - - - - -
HMMFCFNL_00288 9.75e-79 - - - - - - - -
HMMFCFNL_00289 3.32e-39 - - - - - - - -
HMMFCFNL_00290 3.61e-61 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
HMMFCFNL_00291 1.23e-32 - - - S - - - Phage gp6-like head-tail connector protein
HMMFCFNL_00292 2.66e-39 - - - S - - - peptidoglycan catabolic process
HMMFCFNL_00293 5.37e-09 - - - S - - - peptidoglycan catabolic process
HMMFCFNL_00294 2.08e-228 - - - S - - - capsid protein
HMMFCFNL_00295 9.36e-135 - - - S - - - peptidase activity
HMMFCFNL_00296 3.36e-273 - - - S - - - Phage portal protein
HMMFCFNL_00297 2.58e-14 - - - - - - - -
HMMFCFNL_00298 3.55e-280 - - - S - - - Phage Terminase
HMMFCFNL_00299 1e-89 - - - S - - - Phage terminase, small subunit
HMMFCFNL_00300 2.98e-27 - - - - - - - -
HMMFCFNL_00301 1.85e-82 - - - S - - - HNH endonuclease
HMMFCFNL_00307 9.22e-94 - - - L - - - Phage integrase family
HMMFCFNL_00308 3.08e-67 - - - M - - - ArpU family transcriptional regulator
HMMFCFNL_00310 1.82e-36 - - - - - - - -
HMMFCFNL_00314 3.95e-08 - - - - - - - -
HMMFCFNL_00317 4.86e-10 - - - - - - - -
HMMFCFNL_00320 1.83e-62 - - - L ko:K02315,ko:K11144 - ko00000,ko03032 DNA replication protein
HMMFCFNL_00321 2.79e-87 - - - L - - - dnaD_dom DnaD domain protein
HMMFCFNL_00324 2.6e-09 - - - T ko:K21405 - ko00000,ko03000 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HMMFCFNL_00325 8.19e-58 - - - K - - - Helix-turn-helix XRE-family like proteins
HMMFCFNL_00328 8.18e-82 - - - - - - - -
HMMFCFNL_00329 1.03e-166 - - - S - - - Phage integrase family
HMMFCFNL_00331 2.4e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HMMFCFNL_00332 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HMMFCFNL_00333 2.82e-182 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
HMMFCFNL_00334 5.35e-35 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
HMMFCFNL_00335 2.33e-195 yvaM 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Serine aminopeptidase, S33
HMMFCFNL_00336 4.9e-48 yvzC - - K - - - transcriptional
HMMFCFNL_00337 2.36e-91 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
HMMFCFNL_00338 9.82e-92 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
HMMFCFNL_00339 3.85e-72 yvaP - - K - - - transcriptional
HMMFCFNL_00340 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HMMFCFNL_00341 2.26e-144 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
HMMFCFNL_00342 1.37e-219 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HMMFCFNL_00343 1.55e-142 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
HMMFCFNL_00344 1.48e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HMMFCFNL_00345 6.63e-122 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
HMMFCFNL_00346 5.59e-136 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
HMMFCFNL_00347 7.4e-223 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HMMFCFNL_00348 5.63e-145 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
HMMFCFNL_00349 5.58e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HMMFCFNL_00350 8.29e-129 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
HMMFCFNL_00351 2.77e-135 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
HMMFCFNL_00352 1.2e-144 yvbH - - S - - - YvbH-like oligomerisation region
HMMFCFNL_00353 2.28e-156 yvbI - - M - - - Membrane
HMMFCFNL_00354 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
HMMFCFNL_00355 8.03e-105 yvbK - - K - - - acetyltransferase
HMMFCFNL_00356 1.55e-218 - - - EGP - - - Major facilitator Superfamily
HMMFCFNL_00357 1.25e-192 - - - - - - - -
HMMFCFNL_00358 3.24e-148 - - - S - - - GlcNAc-PI de-N-acetylase
HMMFCFNL_00359 3.37e-156 - - - C - - - WbqC-like protein family
HMMFCFNL_00360 2.55e-144 - - - M - - - Protein involved in cellulose biosynthesis
HMMFCFNL_00361 6.97e-198 - - - E - - - UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HMMFCFNL_00362 6.08e-188 arnA 4.2.1.46, 5.1.3.2 - M ko:K01710,ko:K01784 ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130 ko00000,ko00001,ko00002,ko01000 GDP-mannose 4,6 dehydratase
HMMFCFNL_00363 2.26e-235 - 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
HMMFCFNL_00364 1.58e-274 - 1.1.1.136 - M ko:K13015 ko00520,map00520 ko00000,ko00001,ko01000,ko01005 UDP binding domain
HMMFCFNL_00365 2.12e-209 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
HMMFCFNL_00366 1.38e-309 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HMMFCFNL_00367 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
HMMFCFNL_00368 2.12e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HMMFCFNL_00369 1.97e-277 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
HMMFCFNL_00370 5.72e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HMMFCFNL_00371 5.69e-236 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HMMFCFNL_00372 0.0 araE - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HMMFCFNL_00373 1.51e-258 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
HMMFCFNL_00374 2.98e-245 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HMMFCFNL_00375 4.9e-206 yvbU - - K - - - Transcriptional regulator
HMMFCFNL_00376 7.93e-198 yvbV - - EG - - - EamA-like transporter family
HMMFCFNL_00377 7.07e-307 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
HMMFCFNL_00378 1.22e-248 - - - S - - - Glycosyl hydrolase
HMMFCFNL_00379 4.15e-172 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HMMFCFNL_00380 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
HMMFCFNL_00381 1.24e-172 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HMMFCFNL_00382 3.58e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HMMFCFNL_00383 2.1e-134 yvfT 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HMMFCFNL_00384 2.74e-90 yvfT 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HMMFCFNL_00385 2.04e-170 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
HMMFCFNL_00386 7.12e-201 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
HMMFCFNL_00388 1.46e-200 rsbQ - - S ko:K19707 - ko00000,ko03021 Alpha/beta hydrolase family
HMMFCFNL_00389 3.06e-265 - 3.1.3.3 - T ko:K07315 - ko00000,ko01000,ko03021 response regulator
HMMFCFNL_00390 0.0 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
HMMFCFNL_00391 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 beta-galactosidase
HMMFCFNL_00392 3.82e-194 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
HMMFCFNL_00393 5.29e-301 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
HMMFCFNL_00394 4.62e-292 cycB - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
HMMFCFNL_00395 2e-236 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HMMFCFNL_00396 2.79e-145 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
HMMFCFNL_00397 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
HMMFCFNL_00398 6.04e-307 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
HMMFCFNL_00399 5.69e-44 yvfG - - S - - - YvfG protein
HMMFCFNL_00400 1.2e-237 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
HMMFCFNL_00401 1.18e-275 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
HMMFCFNL_00402 3.33e-76 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
HMMFCFNL_00403 9.14e-139 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HMMFCFNL_00404 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HMMFCFNL_00405 1.94e-245 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
HMMFCFNL_00406 1.91e-259 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
HMMFCFNL_00407 1.42e-247 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
HMMFCFNL_00408 8.82e-265 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
HMMFCFNL_00409 5.06e-278 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HMMFCFNL_00410 1.25e-201 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
HMMFCFNL_00411 7.45e-280 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
HMMFCFNL_00412 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
HMMFCFNL_00413 2.28e-149 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
HMMFCFNL_00414 1.61e-157 epsA - - M ko:K19420 - ko00000 biosynthesis protein
HMMFCFNL_00415 3.57e-98 - - - K ko:K19417 - ko00000,ko03000 transcriptional
HMMFCFNL_00416 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
HMMFCFNL_00418 5.4e-120 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
HMMFCFNL_00419 1.75e-93 - - - S - - - Protein of unknown function (DUF3237)
HMMFCFNL_00420 1.51e-163 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
HMMFCFNL_00421 0.0 pbpE - - V - - - Beta-lactamase
HMMFCFNL_00422 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
HMMFCFNL_00423 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
HMMFCFNL_00424 0.0 ybeC - - E - - - amino acid
HMMFCFNL_00425 1.17e-137 yvdT_1 - - K - - - Transcriptional regulator
HMMFCFNL_00426 6.31e-68 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
HMMFCFNL_00427 1.03e-66 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
HMMFCFNL_00428 1.12e-121 yvdQ - - S - - - Protein of unknown function (DUF3231)
HMMFCFNL_00430 8.17e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HMMFCFNL_00431 3.76e-147 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
HMMFCFNL_00432 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
HMMFCFNL_00433 0.0 yvdK 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
HMMFCFNL_00434 5.46e-200 malA - - S - - - Protein of unknown function (DUF1189)
HMMFCFNL_00435 2.79e-189 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
HMMFCFNL_00436 2.48e-310 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
HMMFCFNL_00437 1.71e-301 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
HMMFCFNL_00438 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, N-terminal ig-like domain
HMMFCFNL_00439 6.28e-221 yvdE - - K - - - Transcriptional regulator
HMMFCFNL_00440 2.66e-137 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
HMMFCFNL_00441 7.84e-71 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
HMMFCFNL_00442 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
HMMFCFNL_00443 8.79e-136 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
HMMFCFNL_00444 2.7e-233 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMMFCFNL_00445 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
HMMFCFNL_00446 4.46e-181 yxdL_2 - - V ko:K02003,ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HMMFCFNL_00447 1.13e-250 yvcQ - - T - - - His Kinase A (phosphoacceptor) domain
HMMFCFNL_00448 3.16e-170 yvcP - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HMMFCFNL_00450 9.49e-26 - - - - - - - -
HMMFCFNL_00451 2.8e-183 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
HMMFCFNL_00452 4.59e-49 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
HMMFCFNL_00453 3.63e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
HMMFCFNL_00454 7.84e-226 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
HMMFCFNL_00455 8.53e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
HMMFCFNL_00456 2.39e-117 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HMMFCFNL_00457 1.18e-225 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HMMFCFNL_00458 8.34e-177 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
HMMFCFNL_00459 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
HMMFCFNL_00460 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
HMMFCFNL_00462 0.0 - - - - - - - -
HMMFCFNL_00463 3.68e-171 - - - - - - - -
HMMFCFNL_00464 1.9e-139 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
HMMFCFNL_00465 1.98e-175 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HMMFCFNL_00466 1.8e-164 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HMMFCFNL_00467 1.2e-148 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HMMFCFNL_00468 4.96e-139 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
HMMFCFNL_00469 1.81e-292 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HMMFCFNL_00470 1.06e-147 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HMMFCFNL_00471 2.42e-281 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HMMFCFNL_00472 6.12e-179 yvpB - - NU - - - protein conserved in bacteria
HMMFCFNL_00473 1.05e-151 - 4.2.2.10, 4.2.2.2 - G ko:K19551 ko00040,map00040 ko00000,ko00001,ko01000 Pectate lyase
HMMFCFNL_00474 3.58e-119 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
HMMFCFNL_00475 4.33e-153 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HMMFCFNL_00476 2.06e-208 yvoD - - P - - - COG0370 Fe2 transport system protein B
HMMFCFNL_00477 2.15e-193 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HMMFCFNL_00478 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HMMFCFNL_00479 9.81e-279 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
HMMFCFNL_00480 8.99e-168 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HMMFCFNL_00481 4.29e-171 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
HMMFCFNL_00482 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
HMMFCFNL_00483 4.06e-94 yvnA - - K - - - helix_turn_helix multiple antibiotic resistance protein
HMMFCFNL_00484 2.45e-288 cypX 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
HMMFCFNL_00485 8.35e-176 yvmC 2.3.2.22 - S ko:K17485 - ko00000,ko01000 Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
HMMFCFNL_00486 3.59e-113 yvmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
HMMFCFNL_00487 4.26e-272 yvmA - - EGP - - - Major Facilitator Superfamily
HMMFCFNL_00488 3.8e-66 yvlD - - S ko:K08972 - ko00000 Membrane
HMMFCFNL_00489 1.5e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
HMMFCFNL_00490 9.59e-220 yvlB - - S - - - Putative adhesin
HMMFCFNL_00491 9.45e-64 yvlA - - - - - - -
HMMFCFNL_00492 2.25e-45 yvkN - - - - - - -
HMMFCFNL_00493 3.03e-147 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HMMFCFNL_00494 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HMMFCFNL_00495 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HMMFCFNL_00496 2.54e-42 csbA - - S - - - protein conserved in bacteria
HMMFCFNL_00497 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
HMMFCFNL_00498 1.43e-131 yvkB - - K - - - Transcriptional regulator
HMMFCFNL_00499 1.01e-293 yvkA - - P - - - -transporter
HMMFCFNL_00500 5.48e-281 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HMMFCFNL_00501 1.38e-73 swrA - - S - - - Swarming motility protein
HMMFCFNL_00502 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
HMMFCFNL_00503 5.45e-199 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HMMFCFNL_00504 1.5e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
HMMFCFNL_00505 3.23e-75 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
HMMFCFNL_00506 6.5e-185 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
HMMFCFNL_00507 2e-232 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HMMFCFNL_00508 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HMMFCFNL_00509 1.73e-132 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HMMFCFNL_00510 9.14e-88 - - - - - - - -
HMMFCFNL_00511 8.69e-09 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
HMMFCFNL_00512 5.15e-91 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
HMMFCFNL_00513 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HMMFCFNL_00514 9.02e-76 flaG - - N ko:K06603 - ko00000,ko02035 flagellar protein FlaG
HMMFCFNL_00515 1.44e-104 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HMMFCFNL_00516 2.58e-41 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HMMFCFNL_00517 1.23e-96 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HMMFCFNL_00518 1.7e-92 yviE - - - - - - -
HMMFCFNL_00519 3.8e-197 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
HMMFCFNL_00520 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
HMMFCFNL_00521 7.06e-102 yvyG - - NOU - - - FlgN protein
HMMFCFNL_00522 8.72e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
HMMFCFNL_00523 1.83e-96 yvyF - - S - - - flagellar protein
HMMFCFNL_00524 6.48e-162 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
HMMFCFNL_00525 5.13e-61 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
HMMFCFNL_00526 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HMMFCFNL_00527 4.16e-197 degV - - S - - - protein conserved in bacteria
HMMFCFNL_00528 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HMMFCFNL_00529 2.94e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HMMFCFNL_00530 2.41e-155 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
HMMFCFNL_00531 9.37e-224 yvhJ - - K - - - Transcriptional regulator
HMMFCFNL_00532 2.1e-231 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
HMMFCFNL_00533 1.96e-295 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
HMMFCFNL_00534 8.42e-187 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
HMMFCFNL_00535 1.17e-146 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
HMMFCFNL_00536 0.0 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
HMMFCFNL_00537 0.0 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HMMFCFNL_00538 2.41e-280 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
HMMFCFNL_00539 5.94e-315 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HMMFCFNL_00540 1.49e-143 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HMMFCFNL_00541 1.78e-108 - - - M - - - Glycosyltransferase like family 2
HMMFCFNL_00542 1.66e-260 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
HMMFCFNL_00543 0.0 lytB - - D - - - Stage II sporulation protein
HMMFCFNL_00544 4.58e-16 - - - - - - - -
HMMFCFNL_00545 2.34e-211 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HMMFCFNL_00546 2.03e-272 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HMMFCFNL_00547 1.48e-103 - - - M - - - Glycosyltransferase like family 2
HMMFCFNL_00548 1.53e-119 - - - M - - - Glycosyl transferases group 1
HMMFCFNL_00550 2.74e-208 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
HMMFCFNL_00551 0.0 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HMMFCFNL_00552 1.95e-167 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
HMMFCFNL_00553 5.53e-179 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HMMFCFNL_00554 6.73e-165 - - - M - - - Glycosyltransferase like family 2
HMMFCFNL_00555 7.57e-103 - - - - - - - -
HMMFCFNL_00556 5.87e-134 - - - M - - - Glycosyltransferase like family 2
HMMFCFNL_00557 1.79e-166 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HMMFCFNL_00558 1.32e-73 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
HMMFCFNL_00559 6.82e-111 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HMMFCFNL_00560 3.11e-116 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HMMFCFNL_00561 1.46e-134 tarI 2.7.7.40, 2.7.7.60 - I ko:K00991,ko:K21030 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
HMMFCFNL_00562 5.68e-186 tarJ 1.1.1.137, 1.1.1.405 - E ko:K05352,ko:K21680 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
HMMFCFNL_00563 4.73e-110 tarK 2.7.8.14, 2.7.8.46, 2.7.8.47 - M ko:K18704,ko:K21592 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HMMFCFNL_00564 1.42e-235 tarL 2.7.8.14, 2.7.8.47 - M ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HMMFCFNL_00565 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HMMFCFNL_00566 7.51e-238 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
HMMFCFNL_00567 0.0 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
HMMFCFNL_00568 2.45e-247 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
HMMFCFNL_00569 1.52e-264 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
HMMFCFNL_00570 9.1e-315 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HMMFCFNL_00571 1.42e-220 ywtF_2 - - K - - - Transcriptional regulator
HMMFCFNL_00572 4.69e-201 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
HMMFCFNL_00573 1.37e-304 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HMMFCFNL_00574 2.29e-29 ywtC - - - - - - -
HMMFCFNL_00575 6.34e-276 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
HMMFCFNL_00576 8.44e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
HMMFCFNL_00577 2.95e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
HMMFCFNL_00578 2.68e-227 rbsR - - K ko:K02529 - ko00000,ko03000 transcriptional
HMMFCFNL_00579 1.39e-201 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HMMFCFNL_00580 6.55e-84 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HMMFCFNL_00581 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HMMFCFNL_00582 3.35e-203 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HMMFCFNL_00583 5.22e-203 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
HMMFCFNL_00584 9.76e-120 batE - - T - - - Sh3 type 3 domain protein
HMMFCFNL_00585 3.75e-63 ywsA - - S - - - Protein of unknown function (DUF3892)
HMMFCFNL_00586 3.57e-125 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
HMMFCFNL_00587 1.84e-187 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
HMMFCFNL_00588 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
HMMFCFNL_00589 3.36e-218 alsR - - K - - - LysR substrate binding domain
HMMFCFNL_00590 1.32e-278 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HMMFCFNL_00591 1.06e-162 ywrJ - - - - - - -
HMMFCFNL_00592 6.97e-172 cotB - - - ko:K06325 - ko00000 -
HMMFCFNL_00593 8.48e-265 cotH - - M ko:K06330 - ko00000 Spore Coat
HMMFCFNL_00594 1e-17 - - - - - - - -
HMMFCFNL_00595 5.08e-142 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HMMFCFNL_00596 2.78e-71 - - - S - - - Domain of unknown function (DUF4181)
HMMFCFNL_00597 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
HMMFCFNL_00598 2.79e-107 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
HMMFCFNL_00599 4.53e-132 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
HMMFCFNL_00600 6.07e-114 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
HMMFCFNL_00601 8.38e-148 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
HMMFCFNL_00603 2.36e-301 ywqJ - - S - - - Pre-toxin TG
HMMFCFNL_00604 2.17e-52 ywqI - - S - - - Family of unknown function (DUF5344)
HMMFCFNL_00606 3.59e-197 ywqG - - S - - - Domain of unknown function (DUF1963)
HMMFCFNL_00607 1.63e-313 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HMMFCFNL_00608 1.44e-179 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
HMMFCFNL_00609 1.06e-152 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
HMMFCFNL_00610 5.33e-163 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
HMMFCFNL_00611 3.6e-25 - - - - - - - -
HMMFCFNL_00612 0.0 ywqB - - S - - - SWIM zinc finger
HMMFCFNL_00613 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
HMMFCFNL_00614 1.24e-200 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
HMMFCFNL_00615 1.96e-179 glcR - - K ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
HMMFCFNL_00616 8.53e-76 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
HMMFCFNL_00617 5.26e-88 ywpG - - - - - - -
HMMFCFNL_00618 2.53e-88 ywpF - - S - - - YwpF-like protein
HMMFCFNL_00619 3.54e-108 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
HMMFCFNL_00620 0.0 - - - M - - - cell wall anchor domain
HMMFCFNL_00621 1.68e-221 M1-574 - - T - - - Transcriptional regulatory protein, C terminal
HMMFCFNL_00622 0.0 ywpD - - T - - - Histidine kinase
HMMFCFNL_00623 5.62e-78 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HMMFCFNL_00624 6.89e-107 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HMMFCFNL_00625 7.42e-255 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
HMMFCFNL_00626 1.17e-181 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
HMMFCFNL_00627 5.07e-172 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
HMMFCFNL_00628 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
HMMFCFNL_00629 4.88e-59 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
HMMFCFNL_00630 8.45e-92 - - - K - - - COG1846 Transcriptional regulators
HMMFCFNL_00631 1.37e-269 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
HMMFCFNL_00633 1.97e-310 ywoF - - P - - - Right handed beta helix region
HMMFCFNL_00634 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
HMMFCFNL_00635 1.88e-307 ywoD - - EGP - - - Major facilitator superfamily
HMMFCFNL_00636 2.56e-134 yjgF - - Q - - - Isochorismatase family
HMMFCFNL_00637 5.04e-101 - - - - - - - -
HMMFCFNL_00638 6.5e-288 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
HMMFCFNL_00639 4.51e-77 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
HMMFCFNL_00640 6.02e-135 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
HMMFCFNL_00641 1.63e-95 ywnJ - - S - - - VanZ like family
HMMFCFNL_00642 1.85e-161 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
HMMFCFNL_00643 1.55e-116 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
HMMFCFNL_00644 6.95e-21 ywnC - - S - - - Family of unknown function (DUF5362)
HMMFCFNL_00645 7.07e-92 ywnF - - S - - - Family of unknown function (DUF5392)
HMMFCFNL_00646 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HMMFCFNL_00647 2.81e-183 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
HMMFCFNL_00648 8.72e-78 ywnC - - S - - - Family of unknown function (DUF5362)
HMMFCFNL_00649 1.29e-148 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
HMMFCFNL_00650 4.58e-85 ywnA - - K - - - Transcriptional regulator
HMMFCFNL_00651 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HMMFCFNL_00652 1.12e-83 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
HMMFCFNL_00653 8.2e-68 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
HMMFCFNL_00654 5.43e-28 - - - E ko:K11963 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
HMMFCFNL_00655 1.11e-21 csbD - - K - - - CsbD-like
HMMFCFNL_00656 1.21e-109 ywmF - - S - - - Peptidase M50
HMMFCFNL_00657 3.1e-129 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
HMMFCFNL_00658 1.08e-245 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HMMFCFNL_00659 9.06e-187 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HMMFCFNL_00661 8.34e-155 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
HMMFCFNL_00662 1.89e-157 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
HMMFCFNL_00663 1.02e-235 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
HMMFCFNL_00664 4.96e-306 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HMMFCFNL_00665 2.3e-172 ywmB - - S - - - TATA-box binding
HMMFCFNL_00666 4.54e-45 ywzB - - S - - - membrane
HMMFCFNL_00667 7.16e-114 ywmA - - - - - - -
HMMFCFNL_00668 3.89e-72 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
HMMFCFNL_00669 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HMMFCFNL_00670 4.46e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HMMFCFNL_00671 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HMMFCFNL_00672 1.95e-116 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HMMFCFNL_00673 2.62e-79 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HMMFCFNL_00674 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HMMFCFNL_00675 6.06e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
HMMFCFNL_00676 1.91e-81 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
HMMFCFNL_00677 5.5e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HMMFCFNL_00678 1.25e-302 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HMMFCFNL_00679 2.49e-123 ywlG - - S - - - Belongs to the UPF0340 family
HMMFCFNL_00680 2.35e-106 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
HMMFCFNL_00681 1.58e-100 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HMMFCFNL_00682 4.56e-117 mntP - - P - - - Probably functions as a manganese efflux pump
HMMFCFNL_00683 7.37e-251 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HMMFCFNL_00684 1.79e-100 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
HMMFCFNL_00685 2.29e-152 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
HMMFCFNL_00686 9.69e-74 ywlA - - S - - - Uncharacterised protein family (UPF0715)
HMMFCFNL_00688 1.2e-204 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HMMFCFNL_00689 9.95e-245 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HMMFCFNL_00690 5.43e-88 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HMMFCFNL_00691 1.72e-116 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
HMMFCFNL_00692 3.24e-204 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
HMMFCFNL_00693 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
HMMFCFNL_00694 9.96e-135 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
HMMFCFNL_00695 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
HMMFCFNL_00696 5.53e-303 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HMMFCFNL_00697 2.03e-224 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
HMMFCFNL_00698 2.26e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HMMFCFNL_00699 5.69e-147 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HMMFCFNL_00700 7.82e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
HMMFCFNL_00701 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
HMMFCFNL_00702 6.41e-118 ywjG - - S - - - Domain of unknown function (DUF2529)
HMMFCFNL_00703 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HMMFCFNL_00704 1.03e-82 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HMMFCFNL_00705 4.24e-269 acdA - - I - - - acyl-CoA dehydrogenase
HMMFCFNL_00706 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
HMMFCFNL_00707 1.85e-284 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HMMFCFNL_00708 4.88e-236 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
HMMFCFNL_00709 1.32e-57 ywjC - - - - - - -
HMMFCFNL_00710 1.29e-122 ywjB - - H - - - RibD C-terminal domain
HMMFCFNL_00711 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
HMMFCFNL_00712 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HMMFCFNL_00713 1.02e-159 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
HMMFCFNL_00714 1.13e-121 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
HMMFCFNL_00715 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
HMMFCFNL_00716 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HMMFCFNL_00717 8.67e-111 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
HMMFCFNL_00718 2.06e-176 ywiC - - S - - - YwiC-like protein
HMMFCFNL_00719 3.27e-168 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
HMMFCFNL_00720 4.81e-274 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
HMMFCFNL_00721 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
HMMFCFNL_00722 4.64e-96 ywiB - - S - - - protein conserved in bacteria
HMMFCFNL_00723 3.71e-12 - - - S - - - Bacteriocin subtilosin A
HMMFCFNL_00724 0.0 - - - C ko:K22227 - ko00000 Fe-S oxidoreductases
HMMFCFNL_00726 1.23e-168 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HMMFCFNL_00727 2.94e-298 mgtA 3.6.3.2 - P ko:K01531,ko:K16905 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPase, P-type transporting, HAD superfamily, subfamily IC
HMMFCFNL_00728 1.7e-276 - 2.7.1.26, 2.7.7.2 - L ko:K07263,ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase, M16
HMMFCFNL_00729 4.68e-315 - - - L - - - Peptidase, M16
HMMFCFNL_00731 9.89e-315 ywhL - - CO - - - amine dehydrogenase activity
HMMFCFNL_00732 9.47e-275 ywhK - - CO - - - amine dehydrogenase activity
HMMFCFNL_00733 5.77e-100 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
HMMFCFNL_00735 2.38e-24 - - - S - - - Aminoacyl-tRNA editing domain
HMMFCFNL_00737 2.99e-215 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
HMMFCFNL_00738 1.93e-204 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HMMFCFNL_00739 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HMMFCFNL_00740 2.1e-64 - - - - - - - -
HMMFCFNL_00741 5.51e-123 ywhD - - S - - - YwhD family
HMMFCFNL_00742 3.29e-154 ywhC - - S - - - Peptidase family M50
HMMFCFNL_00743 1.43e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
HMMFCFNL_00744 1.76e-94 ywhA - - K - - - Transcriptional regulator
HMMFCFNL_00745 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HMMFCFNL_00747 1.52e-300 mmr - - U ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
HMMFCFNL_00748 3.15e-103 yffB - - K - - - Transcriptional regulator
HMMFCFNL_00749 1.47e-115 ywgA - - - ko:K09388 - ko00000 -
HMMFCFNL_00750 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
HMMFCFNL_00751 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
HMMFCFNL_00752 5.39e-145 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
HMMFCFNL_00753 8.35e-200 ywfM - - EG ko:K03298 - ko00000,ko02000 EamA-like transporter family
HMMFCFNL_00754 2.15e-199 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HMMFCFNL_00755 3.73e-209 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
HMMFCFNL_00756 1.67e-224 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
HMMFCFNL_00757 9.83e-187 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
HMMFCFNL_00758 3.93e-175 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
HMMFCFNL_00759 1.74e-294 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
HMMFCFNL_00760 3.07e-265 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
HMMFCFNL_00761 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
HMMFCFNL_00762 2.69e-179 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HMMFCFNL_00763 1.24e-175 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
HMMFCFNL_00764 5.11e-146 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
HMMFCFNL_00765 1.77e-144 ywfA - - EGP - - - -transporter
HMMFCFNL_00766 1.22e-92 ywfA - - EGP - - - -transporter
HMMFCFNL_00767 2.65e-316 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
HMMFCFNL_00768 0.0 rocB - - E - - - arginine degradation protein
HMMFCFNL_00769 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
HMMFCFNL_00770 5.19e-311 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
HMMFCFNL_00771 6.13e-100 - - - - - - - -
HMMFCFNL_00772 3.07e-112 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
HMMFCFNL_00773 1.41e-205 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HMMFCFNL_00774 7.47e-233 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HMMFCFNL_00775 2.5e-176 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HMMFCFNL_00776 4.91e-241 spsG - - M - - - Spore Coat
HMMFCFNL_00777 3.01e-165 spsF - - M ko:K07257 - ko00000 Spore Coat
HMMFCFNL_00778 2.27e-270 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
HMMFCFNL_00779 1.04e-210 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
HMMFCFNL_00780 6.44e-285 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
HMMFCFNL_00781 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
HMMFCFNL_00782 1.15e-186 spsA - - M - - - Spore Coat
HMMFCFNL_00783 7.3e-112 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HMMFCFNL_00784 1.59e-78 ywdK - - S - - - small membrane protein
HMMFCFNL_00785 1.86e-303 ywdJ - - F - - - Xanthine uracil
HMMFCFNL_00786 1.08e-63 ywdI - - S - - - Family of unknown function (DUF5327)
HMMFCFNL_00787 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HMMFCFNL_00788 9.47e-166 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HMMFCFNL_00789 1.34e-191 ywdF - - S - - - Glycosyltransferase like family 2
HMMFCFNL_00791 2.06e-144 ywdD - - - - - - -
HMMFCFNL_00792 5.37e-74 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
HMMFCFNL_00793 1.28e-186 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HMMFCFNL_00794 6.19e-39 ywdA - - - - - - -
HMMFCFNL_00795 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
HMMFCFNL_00796 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HMMFCFNL_00797 2.91e-180 - - - P ko:K02598 - ko00000,ko02000 Formate/nitrite transporter
HMMFCFNL_00798 3.03e-192 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
HMMFCFNL_00800 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HMMFCFNL_00801 3.44e-238 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HMMFCFNL_00802 2.31e-178 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
HMMFCFNL_00803 5.53e-240 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
HMMFCFNL_00804 7.78e-262 - - - S - - - Acetyltransferase
HMMFCFNL_00805 6.61e-52 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
HMMFCFNL_00806 1.12e-83 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
HMMFCFNL_00807 1.2e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
HMMFCFNL_00808 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HMMFCFNL_00809 6.94e-226 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HMMFCFNL_00810 5.11e-49 ydaS - - S - - - membrane
HMMFCFNL_00811 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
HMMFCFNL_00812 7.27e-287 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HMMFCFNL_00813 3.33e-77 gtcA - - S - - - GtrA-like protein
HMMFCFNL_00814 3.42e-158 ywcC - - K - - - transcriptional regulator
HMMFCFNL_00816 2.13e-64 ywcB - - S - - - Protein of unknown function, DUF485
HMMFCFNL_00817 0.0 ywcA - - S ko:K14393 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HMMFCFNL_00818 1.32e-143 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
HMMFCFNL_00819 8.23e-288 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
HMMFCFNL_00820 1.7e-246 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
HMMFCFNL_00821 0.0 - - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
HMMFCFNL_00822 1.09e-149 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HMMFCFNL_00823 3.25e-185 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HMMFCFNL_00824 1.8e-198 ywbI - - K - - - Transcriptional regulator
HMMFCFNL_00825 1.1e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
HMMFCFNL_00826 1.21e-143 ywbG - - M - - - effector of murein hydrolase
HMMFCFNL_00827 3.55e-278 ywbF - - EGP ko:K05820 - ko00000,ko02000 Nucleoside H+ symporter
HMMFCFNL_00828 3.13e-38 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
HMMFCFNL_00829 5.68e-280 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
HMMFCFNL_00830 1.99e-87 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
HMMFCFNL_00831 1.02e-160 ywbB - - S - - - Protein of unknown function (DUF2711)
HMMFCFNL_00832 1.59e-315 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMMFCFNL_00833 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HMMFCFNL_00834 1.45e-312 sacX 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HMMFCFNL_00835 2.6e-195 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
HMMFCFNL_00836 1.87e-216 gspA - - M - - - General stress
HMMFCFNL_00837 1.17e-156 ywaF - - S - - - Integral membrane protein
HMMFCFNL_00838 1.46e-113 ywaE - - K - - - Transcriptional regulator
HMMFCFNL_00839 1.1e-297 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HMMFCFNL_00840 0.0 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
HMMFCFNL_00841 2.52e-149 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
HMMFCFNL_00842 5.7e-210 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
HMMFCFNL_00843 1.27e-20 - - - S - - - D-Ala-teichoic acid biosynthesis protein
HMMFCFNL_00844 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMMFCFNL_00845 2.68e-296 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
HMMFCFNL_00846 6.83e-50 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMMFCFNL_00847 4.09e-294 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HMMFCFNL_00848 2.91e-178 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
HMMFCFNL_00849 1.25e-262 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
HMMFCFNL_00850 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HMMFCFNL_00851 1.58e-50 licA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HMMFCFNL_00852 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMMFCFNL_00853 1.89e-67 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
HMMFCFNL_00854 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
HMMFCFNL_00855 8.94e-28 yxzF - - - - - - -
HMMFCFNL_00856 3.23e-145 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
HMMFCFNL_00857 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
HMMFCFNL_00858 8.28e-273 yxlH - - EGP - - - Major Facilitator Superfamily
HMMFCFNL_00859 1.61e-178 yxlG - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HMMFCFNL_00860 8.53e-213 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HMMFCFNL_00861 2.17e-39 yxlE - - S - - - Phospholipase_D-nuclease N-terminal
HMMFCFNL_00862 1.63e-39 - - - - - - - -
HMMFCFNL_00863 2.74e-62 yxlC - - S - - - Family of unknown function (DUF5345)
HMMFCFNL_00864 2.6e-124 sigY - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HMMFCFNL_00865 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
HMMFCFNL_00866 1.77e-200 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HMMFCFNL_00867 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
HMMFCFNL_00868 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
HMMFCFNL_00869 1.16e-243 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
HMMFCFNL_00870 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
HMMFCFNL_00871 1.09e-307 cimH - - C - - - COG3493 Na citrate symporter
HMMFCFNL_00872 0.0 - - - O - - - Peptidase family M48
HMMFCFNL_00874 5.28e-199 yxkH - - G - - - Polysaccharide deacetylase
HMMFCFNL_00876 1.71e-05 - - - P ko:K07238 - ko00000,ko02000 transporter
HMMFCFNL_00877 4.68e-11 - - - P ko:K07238 - ko00000,ko02000 transporter
HMMFCFNL_00878 3.44e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HMMFCFNL_00879 7.85e-210 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
HMMFCFNL_00880 0.0 aldY 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HMMFCFNL_00881 2.29e-188 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
HMMFCFNL_00882 4.99e-100 yxkC - - S - - - Domain of unknown function (DUF4352)
HMMFCFNL_00883 6.06e-251 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
HMMFCFNL_00884 2.68e-100 - - - S - - - Protein of unknown function (DUF1453)
HMMFCFNL_00885 4.91e-243 - - - T - - - Signal transduction histidine kinase
HMMFCFNL_00886 1.05e-145 - - - K ko:K02479 - ko00000,ko02022 helix_turn_helix, Lux Regulon
HMMFCFNL_00887 3.16e-298 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
HMMFCFNL_00890 5.11e-106 yxjI - - S - - - LURP-one-related
HMMFCFNL_00891 8.66e-277 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
HMMFCFNL_00892 1.81e-274 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
HMMFCFNL_00893 3.37e-175 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HMMFCFNL_00894 5.91e-151 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HMMFCFNL_00895 6.6e-168 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HMMFCFNL_00896 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
HMMFCFNL_00897 1.52e-179 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
HMMFCFNL_00898 1.21e-268 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HMMFCFNL_00899 1.47e-133 - - - T - - - Domain of unknown function (DUF4163)
HMMFCFNL_00900 6.3e-61 yxiS - - - - - - -
HMMFCFNL_00901 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
HMMFCFNL_00902 4.7e-283 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
HMMFCFNL_00903 1.77e-183 bglS - - M - - - licheninase activity
HMMFCFNL_00904 5.66e-193 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
HMMFCFNL_00905 2.75e-145 - - - - - - - -
HMMFCFNL_00906 8.94e-291 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
HMMFCFNL_00907 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
HMMFCFNL_00908 9.26e-270 - - - E - - - GDSL-like Lipase/Acylhydrolase
HMMFCFNL_00909 7e-70 - - - K - - - Transcriptional regulator PadR-like family
HMMFCFNL_00910 3.98e-80 - - - S - - - Protein of unknown function (DUF2812)
HMMFCFNL_00913 4.75e-57 yxiJ - - S - - - YxiJ-like protein
HMMFCFNL_00914 1.37e-109 yxiI - - S - - - Protein of unknown function (DUF2716)
HMMFCFNL_00915 7.87e-179 - - - - - - - -
HMMFCFNL_00916 2.81e-90 yxiG - - - - - - -
HMMFCFNL_00917 2.55e-48 - - - - - - - -
HMMFCFNL_00918 3.43e-209 yxxF - - EG - - - EamA-like transporter family
HMMFCFNL_00919 8.5e-95 yxiE - - T - - - Belongs to the universal stress protein A family
HMMFCFNL_00920 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HMMFCFNL_00921 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HMMFCFNL_00922 5.07e-24 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2247)
HMMFCFNL_00923 3.96e-27 - - - - - - - -
HMMFCFNL_00924 6.18e-37 - - - - - - - -
HMMFCFNL_00926 1.39e-79 - - - - - - - -
HMMFCFNL_00927 6.87e-36 - - - - - - - -
HMMFCFNL_00928 1.34e-55 - - - - - - - -
HMMFCFNL_00929 5.41e-73 - - - - - - - -
HMMFCFNL_00930 9.02e-277 - - - S ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
HMMFCFNL_00931 1.33e-52 yxiC - - S - - - Family of unknown function (DUF5344)
HMMFCFNL_00932 3.79e-37 - - - S - - - Domain of unknown function (DUF5082)
HMMFCFNL_00933 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
HMMFCFNL_00935 7.02e-103 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
HMMFCFNL_00936 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
HMMFCFNL_00937 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HMMFCFNL_00938 9.1e-299 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
HMMFCFNL_00939 7.71e-228 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
HMMFCFNL_00940 0.0 ybgF - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
HMMFCFNL_00941 3.3e-298 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
HMMFCFNL_00942 1.92e-263 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HMMFCFNL_00943 8.3e-150 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HMMFCFNL_00944 8.24e-220 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HMMFCFNL_00948 1.4e-83 - - - - - - - -
HMMFCFNL_00950 4.98e-85 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HMMFCFNL_00953 1.51e-196 - - - S - - - Domain of Unknown Function (DUF1206)
HMMFCFNL_00954 2.21e-255 eutH - - E ko:K04023 - ko00000 Ethanolamine utilisation protein, EutH
HMMFCFNL_00955 1.02e-314 yxeQ - - S - - - MmgE/PrpD family
HMMFCFNL_00956 5.82e-272 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
HMMFCFNL_00957 1.67e-171 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HMMFCFNL_00958 1.81e-149 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
HMMFCFNL_00959 8.69e-186 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
HMMFCFNL_00960 1.8e-120 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HMMFCFNL_00961 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HMMFCFNL_00962 1.57e-236 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
HMMFCFNL_00963 4.49e-191 yxeH - - S - - - hydrolases of the HAD superfamily
HMMFCFNL_00966 5.99e-41 yxeE - - - - - - -
HMMFCFNL_00967 7.57e-28 yxeD - - - - - - -
HMMFCFNL_00968 6.79e-91 - - - - - - - -
HMMFCFNL_00969 4.1e-224 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HMMFCFNL_00970 5.95e-77 yxeA - - S - - - Protein of unknown function (DUF1093)
HMMFCFNL_00971 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
HMMFCFNL_00972 4.46e-180 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HMMFCFNL_00973 2.13e-228 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HMMFCFNL_00974 2.8e-160 yxdJ - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HMMFCFNL_00975 4.69e-203 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
HMMFCFNL_00976 5.63e-194 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
HMMFCFNL_00977 1.87e-213 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
HMMFCFNL_00978 1.55e-251 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HMMFCFNL_00979 4.01e-296 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
HMMFCFNL_00980 4.27e-223 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HMMFCFNL_00981 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HMMFCFNL_00982 1.23e-227 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HMMFCFNL_00983 4.9e-200 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HMMFCFNL_00984 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HMMFCFNL_00985 2.6e-177 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
HMMFCFNL_00986 1.74e-224 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
HMMFCFNL_00988 2.13e-64 yxcD - - S - - - Protein of unknown function (DUF2653)
HMMFCFNL_00989 1.02e-313 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HMMFCFNL_00990 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
HMMFCFNL_00992 2.4e-192 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
HMMFCFNL_00993 5.35e-268 yxbF - - K - - - Bacterial regulatory proteins, tetR family
HMMFCFNL_00994 3.42e-313 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HMMFCFNL_00995 6.82e-14 yxaI - - S - - - membrane protein domain
HMMFCFNL_00996 1.4e-134 yxaL - - S - - - PQQ-like domain
HMMFCFNL_00997 8.92e-80 - - - S - - - Family of unknown function (DUF5391)
HMMFCFNL_00998 4.03e-99 yxaI - - S - - - membrane protein domain
HMMFCFNL_00999 5.11e-284 - - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
HMMFCFNL_01000 1.05e-250 - 1.13.11.24 - S ko:K07155 - ko00000,ko01000 AraC-like ligand binding domain
HMMFCFNL_01001 3.22e-129 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
HMMFCFNL_01002 2.13e-255 yxnA - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HMMFCFNL_01003 6.83e-94 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HMMFCFNL_01004 3.23e-78 - - - S ko:K06518 - ko00000,ko02000 LrgA family
HMMFCFNL_01005 1.27e-152 yxaC - - M - - - effector of murein hydrolase
HMMFCFNL_01006 1.04e-244 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
HMMFCFNL_01007 4.21e-266 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
HMMFCFNL_01008 4.42e-164 gntR - - K ko:K11476 - ko00000,ko03000 transcriptional
HMMFCFNL_01009 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
HMMFCFNL_01010 2.05e-295 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
HMMFCFNL_01011 0.0 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HMMFCFNL_01012 9.33e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
HMMFCFNL_01013 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
HMMFCFNL_01014 6.41e-237 - - - S - - - Polysaccharide pyruvyl transferase
HMMFCFNL_01015 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HMMFCFNL_01016 8.86e-20 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HMMFCFNL_01017 1.08e-156 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
HMMFCFNL_01018 1.44e-24 - - - - - - - -
HMMFCFNL_01019 2.61e-150 - - - S ko:K16916 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
HMMFCFNL_01020 8.4e-143 - - - P ko:K16917 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HMMFCFNL_01021 3.65e-172 - - - O ko:K16922 - ko00000,ko01002 Peptidase M50
HMMFCFNL_01022 2.24e-236 - - - S - - - Radical SAM superfamily
HMMFCFNL_01023 8.12e-17 - - - - - - - -
HMMFCFNL_01024 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
HMMFCFNL_01025 2.01e-16 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2326)
HMMFCFNL_01026 1e-141 - - - - - - - -
HMMFCFNL_01027 1.59e-125 - - - KLT - - - Protein kinase domain
HMMFCFNL_01028 5e-106 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HMMFCFNL_01030 2.39e-75 - - - - - - - -
HMMFCFNL_01031 1.81e-297 yycR 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HMMFCFNL_01033 4.53e-41 yycQ - - S - - - Protein of unknown function (DUF2651)
HMMFCFNL_01034 2.64e-267 yycP - - - - - - -
HMMFCFNL_01035 4.81e-169 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HMMFCFNL_01036 1.45e-108 yycN - - K - - - Acetyltransferase
HMMFCFNL_01037 1.01e-237 - - - S - - - aspartate phosphatase
HMMFCFNL_01039 3.22e-213 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
HMMFCFNL_01040 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
HMMFCFNL_01041 3.38e-293 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
HMMFCFNL_01042 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HMMFCFNL_01043 1.15e-279 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HMMFCFNL_01044 1.15e-190 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
HMMFCFNL_01045 1.2e-200 yycI - - S - - - protein conserved in bacteria
HMMFCFNL_01046 0.0 yycH - - S - - - protein conserved in bacteria
HMMFCFNL_01047 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HMMFCFNL_01048 1.45e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HMMFCFNL_01053 1.29e-314 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HMMFCFNL_01054 9.82e-101 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HMMFCFNL_01055 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
HMMFCFNL_01056 3.48e-40 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
HMMFCFNL_01058 1.89e-22 yycC - - K - - - YycC-like protein
HMMFCFNL_01059 2.83e-281 yycB - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
HMMFCFNL_01060 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HMMFCFNL_01061 2.74e-96 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
HMMFCFNL_01062 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
HMMFCFNL_01063 5.23e-205 yybS - - S - - - membrane
HMMFCFNL_01065 2.89e-110 cotF - - M ko:K06329 - ko00000 Spore coat protein
HMMFCFNL_01066 6.68e-90 yybR - - K - - - Transcriptional regulator
HMMFCFNL_01067 4.89e-210 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
HMMFCFNL_01068 7.84e-91 - - - - - - - -
HMMFCFNL_01070 1.01e-307 yybO - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HMMFCFNL_01071 5.1e-141 - - - K - - - TipAS antibiotic-recognition domain
HMMFCFNL_01072 5.24e-186 - - - - - - - -
HMMFCFNL_01073 3.02e-88 - - - S - - - SnoaL-like domain
HMMFCFNL_01074 1.09e-159 yybG - - S - - - Pentapeptide repeat-containing protein
HMMFCFNL_01075 1.5e-277 yybF - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HMMFCFNL_01076 7.61e-42 yybE - - K - - - Transcriptional regulator
HMMFCFNL_01077 6.1e-131 yybE - - K - - - Transcriptional regulator
HMMFCFNL_01078 2.18e-101 yjcF - - S - - - Acetyltransferase (GNAT) domain
HMMFCFNL_01079 6.78e-32 yybC - - - - - - -
HMMFCFNL_01080 2.02e-35 yybC - - - - - - -
HMMFCFNL_01081 2.16e-164 - - - S - - - Metallo-beta-lactamase superfamily
HMMFCFNL_01082 4.54e-100 yybA - - K - - - transcriptional
HMMFCFNL_01083 1.16e-92 yjcF - - S - - - Acetyltransferase (GNAT) domain
HMMFCFNL_01084 4.28e-125 yyaS - - S ko:K07149 - ko00000 Membrane
HMMFCFNL_01085 1.91e-119 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
HMMFCFNL_01086 7.41e-86 - - - S - - - YjbR
HMMFCFNL_01087 6.31e-139 yyaP - - H - - - RibD C-terminal domain
HMMFCFNL_01088 9.82e-101 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Catalyzes the reduction of arsenate As(V) to arsenite As(III)
HMMFCFNL_01089 6.83e-231 arsB - - P ko:K03325 - ko00000,ko02000 Arsenic resistance protein
HMMFCFNL_01090 1.31e-88 cadI 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HMMFCFNL_01091 2.97e-70 arsR - - K ko:K03892 - ko00000,ko03000 ArsR family transcriptional regulator
HMMFCFNL_01092 1.25e-07 - - - L - - - resolvase
HMMFCFNL_01093 7.7e-09 - - - L - - - Recombinase
HMMFCFNL_01095 3.22e-107 - - - E - - - Transglutaminase-like superfamily
HMMFCFNL_01096 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
HMMFCFNL_01097 5.15e-216 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
HMMFCFNL_01098 0.0 - - - EGP ko:K08369 - ko00000,ko02000 Major facilitator superfamily
HMMFCFNL_01099 2.49e-115 vatD 2.3.1.28, 2.3.1.79 - S ko:K00638,ko:K00661,ko:K18234 - br01600,ko00000,ko01000,ko01504 Bacterial transferase hexapeptide (six repeats)
HMMFCFNL_01100 7.2e-90 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HMMFCFNL_01101 4.83e-227 ccpB - - K - - - Transcriptional regulator
HMMFCFNL_01102 3.43e-186 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
HMMFCFNL_01103 4.25e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HMMFCFNL_01104 1.81e-103 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HMMFCFNL_01105 1.01e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
HMMFCFNL_01106 5.65e-256 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HMMFCFNL_01107 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HMMFCFNL_01108 7.41e-45 yyzM - - S - - - protein conserved in bacteria
HMMFCFNL_01109 1.53e-226 yyaD - - S - - - Membrane
HMMFCFNL_01110 1.3e-144 yyaC - - S - - - Sporulation protein YyaC
HMMFCFNL_01111 3.96e-191 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HMMFCFNL_01112 4.79e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
HMMFCFNL_01113 6.26e-96 - - - S - - - Bacterial PH domain
HMMFCFNL_01114 9e-193 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HMMFCFNL_01115 1.01e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HMMFCFNL_01116 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HMMFCFNL_01117 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HMMFCFNL_01118 1.83e-141 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
HMMFCFNL_01119 9.29e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HMMFCFNL_01120 8.1e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HMMFCFNL_01121 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HMMFCFNL_01122 1.71e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HMMFCFNL_01123 2.24e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
HMMFCFNL_01124 1.85e-263 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HMMFCFNL_01125 1.25e-51 yaaB - - S - - - Domain of unknown function (DUF370)
HMMFCFNL_01126 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HMMFCFNL_01127 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HMMFCFNL_01134 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HMMFCFNL_01135 8.49e-265 glgC 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HMMFCFNL_01136 3.72e-238 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Glucose-1-phosphate adenylyltransferase, GlgD subunit
HMMFCFNL_01137 0.0 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
HMMFCFNL_01138 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HMMFCFNL_01139 8.04e-101 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
HMMFCFNL_01140 5.23e-260 cotI - - S ko:K06331 - ko00000 Spore coat protein
HMMFCFNL_01141 1.18e-274 cotSA - - M ko:K06338 - ko00000 Glycosyl transferases group 1
HMMFCFNL_01142 2.82e-262 cotS - - S ko:K06337 - ko00000 Seems to be required for the assembly of the CotSA protein in spores
HMMFCFNL_01144 1.38e-295 - - - M ko:K06338 - ko00000 Glycosyltransferase Family 4
HMMFCFNL_01145 5.85e-226 ytcB - - M - - - NAD-dependent epimerase dehydratase
HMMFCFNL_01146 1.08e-305 ytcA 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HMMFCFNL_01147 8.09e-195 ytdA 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
HMMFCFNL_01148 8.68e-169 yteA - - T - - - COG1734 DnaK suppressor protein
HMMFCFNL_01149 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
HMMFCFNL_01150 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HMMFCFNL_01151 1.63e-195 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
HMMFCFNL_01152 3.45e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HMMFCFNL_01153 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HMMFCFNL_01154 5.81e-272 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HMMFCFNL_01155 1.53e-216 troA - - P ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HMMFCFNL_01156 9.74e-176 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K11710,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HMMFCFNL_01157 1.23e-294 mntC - - P ko:K11705,ko:K11708,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HMMFCFNL_01158 6.23e-190 mntD - - P ko:K11709,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
HMMFCFNL_01159 2.43e-34 - - - S - - - Domain of Unknown Function (DUF1540)
HMMFCFNL_01160 9.47e-238 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
HMMFCFNL_01161 7.51e-316 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
HMMFCFNL_01162 5.02e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
HMMFCFNL_01163 1.27e-133 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
HMMFCFNL_01164 8.36e-113 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HMMFCFNL_01165 4.78e-95 ytkA - - S - - - YtkA-like
HMMFCFNL_01167 1.8e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
HMMFCFNL_01168 3.2e-81 ytkC - - S - - - Bacteriophage holin family
HMMFCFNL_01169 4.47e-113 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
HMMFCFNL_01170 1.32e-183 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HMMFCFNL_01171 1.5e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HMMFCFNL_01172 2.66e-240 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HMMFCFNL_01173 5.48e-190 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HMMFCFNL_01174 2.85e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
HMMFCFNL_01175 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HMMFCFNL_01176 2.26e-286 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HMMFCFNL_01177 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
HMMFCFNL_01178 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
HMMFCFNL_01179 8.35e-88 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HMMFCFNL_01180 4.7e-192 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
HMMFCFNL_01181 4.81e-276 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
HMMFCFNL_01182 4.57e-135 ytqB - - J - - - Putative rRNA methylase
HMMFCFNL_01183 1.93e-243 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
HMMFCFNL_01184 1.27e-55 ytzC - - S - - - Protein of unknown function (DUF2524)
HMMFCFNL_01186 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
HMMFCFNL_01187 5.96e-207 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HMMFCFNL_01188 2.82e-214 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
HMMFCFNL_01189 1.12e-191 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
HMMFCFNL_01190 5.88e-163 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HMMFCFNL_01191 1.39e-296 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
HMMFCFNL_01192 4.87e-165 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HMMFCFNL_01193 1.9e-231 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
HMMFCFNL_01194 3.14e-178 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
HMMFCFNL_01195 0.0 bceB - - V ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
HMMFCFNL_01196 2.67e-76 yttA - - S - - - Pfam Transposase IS66
HMMFCFNL_01197 9.96e-268 yttB - - EGP - - - Major facilitator superfamily
HMMFCFNL_01198 1.82e-181 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
HMMFCFNL_01199 3.63e-72 ytvB - - S - - - Protein of unknown function (DUF4257)
HMMFCFNL_01200 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
HMMFCFNL_01201 1.22e-68 ytwF - - P - - - Sulfurtransferase
HMMFCFNL_01202 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
HMMFCFNL_01203 7.65e-186 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
HMMFCFNL_01204 2.35e-214 amyD - - P ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HMMFCFNL_01205 1.17e-308 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HMMFCFNL_01206 4.37e-242 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HMMFCFNL_01207 1.13e-219 - - - S - - - Acetyl xylan esterase (AXE1)
HMMFCFNL_01208 2.73e-180 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
HMMFCFNL_01209 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
HMMFCFNL_01210 5.44e-277 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HMMFCFNL_01211 1.09e-158 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HMMFCFNL_01212 6.48e-244 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HMMFCFNL_01213 6.39e-279 bioI 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
HMMFCFNL_01214 5.21e-177 ytbQ 1.1.1.203, 1.1.1.388 - GM ko:K18981,ko:K19243 ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 NAD dependent epimerase/dehydratase family
HMMFCFNL_01215 6.19e-193 ytcP - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
HMMFCFNL_01216 0.0 - - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
HMMFCFNL_01217 0.0 ytdP - - K - - - Transcriptional regulator
HMMFCFNL_01218 1.31e-220 lplB13 - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
HMMFCFNL_01219 1.68e-278 yteR 3.2.1.172 GH105 G ko:K15532 - ko00000,ko01000 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HMMFCFNL_01220 5.57e-93 yteS - - G - - - transport
HMMFCFNL_01221 6.02e-315 yteT - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
HMMFCFNL_01222 3.81e-150 yteU - - S - - - Integral membrane protein
HMMFCFNL_01223 2.14e-36 yteV - - S - - - Sporulation protein Cse60
HMMFCFNL_01224 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
HMMFCFNL_01225 1.41e-293 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
HMMFCFNL_01226 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HMMFCFNL_01227 2.13e-169 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HMMFCFNL_01228 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
HMMFCFNL_01229 2.8e-168 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HMMFCFNL_01230 4.99e-255 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
HMMFCFNL_01231 7.02e-288 pbuO - - S ko:K06901 - ko00000,ko02000 permease
HMMFCFNL_01232 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
HMMFCFNL_01233 3e-221 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HMMFCFNL_01234 2.13e-130 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HMMFCFNL_01235 1.45e-208 ytlQ - - - - - - -
HMMFCFNL_01236 7.44e-230 ytlR - - I - - - Diacylglycerol kinase catalytic domain
HMMFCFNL_01237 0.0 amyX 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
HMMFCFNL_01238 1.75e-191 ytmP - - M - - - Phosphotransferase
HMMFCFNL_01239 9.51e-61 ytzH - - S - - - YtzH-like protein
HMMFCFNL_01240 1.25e-155 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HMMFCFNL_01241 2.61e-191 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
HMMFCFNL_01242 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
HMMFCFNL_01243 1.17e-67 ytzB - - S - - - small secreted protein
HMMFCFNL_01244 3.71e-261 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
HMMFCFNL_01245 7.02e-103 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
HMMFCFNL_01246 3.17e-75 ytpP - - CO - - - Thioredoxin
HMMFCFNL_01247 2.4e-190 ytpQ - - S - - - Belongs to the UPF0354 family
HMMFCFNL_01248 1.78e-140 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HMMFCFNL_01249 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
HMMFCFNL_01250 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
HMMFCFNL_01251 1.67e-63 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HMMFCFNL_01252 3.17e-30 ytxH - - S - - - COG4980 Gas vesicle protein
HMMFCFNL_01253 6.39e-71 ytxJ - - O - - - Protein of unknown function (DUF2847)
HMMFCFNL_01254 7.64e-250 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
HMMFCFNL_01255 8.4e-235 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
HMMFCFNL_01256 6.84e-187 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
HMMFCFNL_01257 1.6e-161 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
HMMFCFNL_01258 1.81e-290 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
HMMFCFNL_01259 6.16e-152 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
HMMFCFNL_01260 2.43e-156 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
HMMFCFNL_01261 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HMMFCFNL_01262 6.47e-304 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HMMFCFNL_01264 2.01e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HMMFCFNL_01265 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
HMMFCFNL_01266 1.13e-113 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
HMMFCFNL_01267 1.2e-141 yttP - - K - - - Transcriptional regulator
HMMFCFNL_01268 1.52e-197 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
HMMFCFNL_01269 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HMMFCFNL_01270 1.17e-304 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HMMFCFNL_01271 5.3e-264 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
HMMFCFNL_01272 6.26e-289 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HMMFCFNL_01273 2.12e-40 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
HMMFCFNL_01274 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HMMFCFNL_01275 0.0 ytcJ - - S - - - amidohydrolase
HMMFCFNL_01276 2.4e-189 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HMMFCFNL_01277 9.73e-230 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
HMMFCFNL_01278 1.37e-110 yteJ - - S - - - RDD family
HMMFCFNL_01279 1.14e-146 ytfI - - S - - - Protein of unknown function (DUF2953)
HMMFCFNL_01280 1.06e-94 ytfJ - - S - - - Sporulation protein YtfJ
HMMFCFNL_01281 1.12e-115 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HMMFCFNL_01282 1.08e-223 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
HMMFCFNL_01283 2.71e-280 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HMMFCFNL_01284 3.31e-114 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
HMMFCFNL_01285 4.3e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
HMMFCFNL_01286 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
HMMFCFNL_01288 8.04e-182 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HMMFCFNL_01289 1.91e-166 ytkL - - S - - - Belongs to the UPF0173 family
HMMFCFNL_01290 1.13e-308 ytoI - - K - - - transcriptional regulator containing CBS domains
HMMFCFNL_01291 2.15e-63 ytpI - - S - - - YtpI-like protein
HMMFCFNL_01292 5.04e-230 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
HMMFCFNL_01293 9.5e-39 - - - - - - - -
HMMFCFNL_01294 5.12e-112 ytrI - - - - - - -
HMMFCFNL_01295 2.45e-75 ytrH - - S - - - Sporulation protein YtrH
HMMFCFNL_01296 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
HMMFCFNL_01297 8.53e-287 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
HMMFCFNL_01298 1.25e-207 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HMMFCFNL_01299 9.82e-234 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HMMFCFNL_01300 4.65e-229 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HMMFCFNL_01301 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
HMMFCFNL_01302 4.68e-82 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
HMMFCFNL_01303 2.73e-245 ytvI - - S - - - sporulation integral membrane protein YtvI
HMMFCFNL_01304 9.38e-95 ytwI - - S - - - membrane
HMMFCFNL_01305 1.17e-267 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
HMMFCFNL_01306 9.27e-309 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
HMMFCFNL_01307 1.04e-217 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
HMMFCFNL_01308 3.27e-169 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HMMFCFNL_01309 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
HMMFCFNL_01310 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HMMFCFNL_01311 1.65e-201 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HMMFCFNL_01312 1.68e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
HMMFCFNL_01313 2.82e-126 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HMMFCFNL_01314 4.54e-205 ytbE - - S - - - reductase
HMMFCFNL_01315 4.46e-259 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
HMMFCFNL_01316 9.85e-88 ytcD - - K - - - Transcriptional regulator
HMMFCFNL_01317 1.22e-246 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HMMFCFNL_01318 2.42e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HMMFCFNL_01319 2.42e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HMMFCFNL_01320 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
HMMFCFNL_01321 1e-219 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
HMMFCFNL_01322 1.33e-141 ytxB - - S - - - SNARE associated Golgi protein
HMMFCFNL_01323 3.46e-205 ytxC - - S - - - YtxC-like family
HMMFCFNL_01325 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HMMFCFNL_01326 1.98e-189 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
HMMFCFNL_01327 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HMMFCFNL_01328 1.96e-166 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
HMMFCFNL_01329 8.47e-85 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HMMFCFNL_01330 5.34e-150 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HMMFCFNL_01332 1.81e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HMMFCFNL_01333 3.93e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
HMMFCFNL_01334 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HMMFCFNL_01335 1.81e-59 ysdA - - S - - - Membrane
HMMFCFNL_01336 2.79e-89 ysdB - - S - - - Sigma-w pathway protein YsdB
HMMFCFNL_01337 4.35e-262 ysdC - - G - - - COG1363 Cellulase M and related proteins
HMMFCFNL_01338 9.92e-242 - 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
HMMFCFNL_01339 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
HMMFCFNL_01340 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
HMMFCFNL_01341 1.7e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HMMFCFNL_01342 1.17e-184 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
HMMFCFNL_01343 7.5e-282 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
HMMFCFNL_01344 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
HMMFCFNL_01345 1.94e-218 araP - - G ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
HMMFCFNL_01346 6.34e-192 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
HMMFCFNL_01347 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
HMMFCFNL_01348 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
HMMFCFNL_01349 3.43e-68 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase-like domain
HMMFCFNL_01350 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
HMMFCFNL_01351 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Glycolate oxidase subunit
HMMFCFNL_01352 2.93e-259 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
HMMFCFNL_01353 4.37e-43 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
HMMFCFNL_01354 3.13e-171 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HMMFCFNL_01355 1.81e-250 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HMMFCFNL_01356 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HMMFCFNL_01357 9.9e-214 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HMMFCFNL_01358 1.04e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HMMFCFNL_01359 1.55e-111 yshB - - S - - - membrane protein, required for colicin V production
HMMFCFNL_01360 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
HMMFCFNL_01361 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HMMFCFNL_01362 3.76e-89 yshE - - S ko:K08989 - ko00000 membrane
HMMFCFNL_01363 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HMMFCFNL_01364 2.34e-128 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
HMMFCFNL_01365 3.12e-176 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
HMMFCFNL_01366 2.58e-179 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
HMMFCFNL_01367 1.43e-226 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
HMMFCFNL_01369 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
HMMFCFNL_01370 1.12e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
HMMFCFNL_01371 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HMMFCFNL_01372 3.96e-275 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HMMFCFNL_01373 8.53e-104 yslB - - S - - - Protein of unknown function (DUF2507)
HMMFCFNL_01374 1.35e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
HMMFCFNL_01375 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
HMMFCFNL_01376 2.33e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
HMMFCFNL_01377 2.18e-101 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
HMMFCFNL_01378 1.81e-41 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
HMMFCFNL_01379 1.6e-98 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
HMMFCFNL_01380 4.49e-194 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
HMMFCFNL_01381 1.62e-255 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
HMMFCFNL_01382 2.04e-170 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HMMFCFNL_01383 7.86e-132 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HMMFCFNL_01384 4.05e-119 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
HMMFCFNL_01386 7.92e-182 ysnF - - S - - - protein conserved in bacteria
HMMFCFNL_01387 3.31e-98 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
HMMFCFNL_01389 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
HMMFCFNL_01390 5.05e-110 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
HMMFCFNL_01391 9.59e-245 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HMMFCFNL_01392 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HMMFCFNL_01393 2.04e-253 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HMMFCFNL_01394 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HMMFCFNL_01395 2.55e-148 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HMMFCFNL_01396 3.19e-239 ysoA - - H - - - Tetratricopeptide repeat
HMMFCFNL_01397 2.54e-286 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HMMFCFNL_01398 1.15e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HMMFCFNL_01399 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
HMMFCFNL_01400 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HMMFCFNL_01401 7.6e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
HMMFCFNL_01402 4.77e-116 ysxD - - - - - - -
HMMFCFNL_01403 2.74e-315 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HMMFCFNL_01404 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
HMMFCFNL_01405 5.15e-219 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HMMFCFNL_01406 1.01e-183 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
HMMFCFNL_01407 2.14e-232 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
HMMFCFNL_01408 1.01e-311 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
HMMFCFNL_01409 0.0 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
HMMFCFNL_01410 2.39e-252 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HMMFCFNL_01411 1.53e-35 - - - - - - - -
HMMFCFNL_01412 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HMMFCFNL_01413 1.55e-315 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
HMMFCFNL_01414 3.08e-162 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HMMFCFNL_01415 1.66e-208 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
HMMFCFNL_01416 1.73e-132 maf - - D ko:K06287 - ko00000 septum formation protein Maf
HMMFCFNL_01417 8.35e-163 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
HMMFCFNL_01418 5.26e-235 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
HMMFCFNL_01419 7.78e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
HMMFCFNL_01420 8.72e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
HMMFCFNL_01421 4.3e-158 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HMMFCFNL_01422 4.82e-185 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
HMMFCFNL_01423 3.03e-186 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
HMMFCFNL_01424 3.08e-207 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
HMMFCFNL_01425 6.34e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
HMMFCFNL_01426 2.66e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
HMMFCFNL_01427 2.7e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
HMMFCFNL_01428 4.25e-139 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
HMMFCFNL_01429 5.59e-308 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HMMFCFNL_01430 4.75e-96 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
HMMFCFNL_01431 1.43e-208 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
HMMFCFNL_01432 5.02e-123 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
HMMFCFNL_01433 4.76e-290 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
HMMFCFNL_01434 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
HMMFCFNL_01435 1.02e-201 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
HMMFCFNL_01436 5.14e-269 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HMMFCFNL_01437 6.96e-217 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
HMMFCFNL_01438 2.55e-70 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HMMFCFNL_01439 3.51e-164 yebC - - K - - - transcriptional regulatory protein
HMMFCFNL_01440 0.0 yrbD - - E ko:K03310 - ko00000 Sodium alanine symporter
HMMFCFNL_01441 1.09e-68 - - - S - - - Family of unknown function (DUF5412)
HMMFCFNL_01443 1.91e-151 yrzF - - T - - - serine threonine protein kinase
HMMFCFNL_01444 4.59e-247 idhA 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
HMMFCFNL_01445 0.0 csbX - - EGP - - - the major facilitator superfamily
HMMFCFNL_01446 1.85e-120 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
HMMFCFNL_01447 2.84e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HMMFCFNL_01448 9.14e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HMMFCFNL_01449 2.91e-30 yrzS - - S - - - Protein of unknown function (DUF2905)
HMMFCFNL_01450 6.03e-248 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HMMFCFNL_01451 4.74e-292 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HMMFCFNL_01452 1.29e-52 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
HMMFCFNL_01453 1.46e-96 yrzE - - S - - - Protein of unknown function (DUF3792)
HMMFCFNL_01454 4.1e-143 yrbG - - S - - - membrane
HMMFCFNL_01455 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HMMFCFNL_01456 5.53e-65 yrzD - - S - - - Post-transcriptional regulator
HMMFCFNL_01457 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HMMFCFNL_01458 6.51e-114 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
HMMFCFNL_01459 1.07e-64 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
HMMFCFNL_01460 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
HMMFCFNL_01461 2.53e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HMMFCFNL_01462 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HMMFCFNL_01463 1.36e-90 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HMMFCFNL_01464 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
HMMFCFNL_01466 7.06e-309 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
HMMFCFNL_01467 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HMMFCFNL_01468 3.96e-177 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HMMFCFNL_01469 6.69e-301 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HMMFCFNL_01470 8.12e-93 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
HMMFCFNL_01471 6.02e-269 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
HMMFCFNL_01472 3.81e-277 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HMMFCFNL_01473 1.01e-20 yrrB - - S - - - COG0457 FOG TPR repeat
HMMFCFNL_01474 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HMMFCFNL_01475 1.44e-107 yrrD - - S - - - protein conserved in bacteria
HMMFCFNL_01476 8.4e-42 yrzR - - - - - - -
HMMFCFNL_01477 5.38e-12 - - - S - - - Protein of unknown function (DUF3918)
HMMFCFNL_01478 2.18e-138 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HMMFCFNL_01479 3.24e-139 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HMMFCFNL_01480 1.01e-184 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
HMMFCFNL_01481 1.28e-167 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
HMMFCFNL_01482 3.07e-242 yrrI - - S - - - AI-2E family transporter
HMMFCFNL_01483 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HMMFCFNL_01484 2.22e-55 yrzL - - S - - - Belongs to the UPF0297 family
HMMFCFNL_01485 5.49e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HMMFCFNL_01486 2.94e-60 yrzB - - S - - - Belongs to the UPF0473 family
HMMFCFNL_01487 7.51e-242 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HMMFCFNL_01488 6.92e-155 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
HMMFCFNL_01489 2.57e-221 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
HMMFCFNL_01490 4.62e-313 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
HMMFCFNL_01491 4.51e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
HMMFCFNL_01492 1.14e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HMMFCFNL_01493 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
HMMFCFNL_01494 8.2e-102 yrrS - - S - - - Protein of unknown function (DUF1510)
HMMFCFNL_01495 4.94e-36 yrzA - - S - - - Protein of unknown function (DUF2536)
HMMFCFNL_01496 1.15e-151 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
HMMFCFNL_01497 9.36e-160 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HMMFCFNL_01498 1.66e-216 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
HMMFCFNL_01499 8.55e-269 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HMMFCFNL_01500 6.93e-49 yrhC - - S - - - YrhC-like protein
HMMFCFNL_01501 1.22e-102 yrhD - - S - - - Protein of unknown function (DUF1641)
HMMFCFNL_01502 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
HMMFCFNL_01503 4.41e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
HMMFCFNL_01504 1.38e-183 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
HMMFCFNL_01506 9.39e-08 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
HMMFCFNL_01507 1.05e-124 yrhH - - Q - - - methyltransferase
HMMFCFNL_01508 2.26e-135 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
HMMFCFNL_01509 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
HMMFCFNL_01510 6.32e-59 yrhK - - S - - - YrhK-like protein
HMMFCFNL_01511 0.0 oatA - - I - - - Acyltransferase family
HMMFCFNL_01512 1.01e-190 rsiV - - S - - - Protein of unknown function (DUF3298)
HMMFCFNL_01513 5.77e-113 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HMMFCFNL_01514 5.9e-194 yrhO - - K - - - Archaeal transcriptional regulator TrmB
HMMFCFNL_01515 5.63e-137 yrhP - - E - - - LysE type translocator
HMMFCFNL_01516 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
HMMFCFNL_01517 0.0 levR - - K - - - PTS system fructose IIA component
HMMFCFNL_01518 1.08e-96 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
HMMFCFNL_01519 6.27e-106 ptnA 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11195 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system mannose fructose sorbose family
HMMFCFNL_01520 2.79e-166 levF - - G ko:K02746,ko:K02795,ko:K11196 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
HMMFCFNL_01521 1.39e-192 levG - - G ko:K02771,ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
HMMFCFNL_01522 0.0 sacC 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
HMMFCFNL_01523 1.58e-116 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
HMMFCFNL_01524 2.78e-252 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
HMMFCFNL_01525 4.53e-33 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 peroxiredoxin activity
HMMFCFNL_01526 3.17e-68 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
HMMFCFNL_01527 7.23e-66 yraD - - M ko:K06439 - ko00000 Spore coat protein
HMMFCFNL_01528 1.23e-35 yraE - - - ko:K06440 - ko00000 -
HMMFCFNL_01529 3.41e-279 adhB 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HMMFCFNL_01530 9.61e-84 yraF - - M - - - Spore coat protein
HMMFCFNL_01531 4.19e-50 yraG - - - ko:K06440 - ko00000 -
HMMFCFNL_01532 5.06e-87 - - - E - - - Glyoxalase-like domain
HMMFCFNL_01533 2.92e-81 - - - T - - - sh3 domain protein
HMMFCFNL_01534 1.33e-79 - - - T - - - sh3 domain protein
HMMFCFNL_01535 1.02e-192 - - - S - - - Alpha beta hydrolase
HMMFCFNL_01536 5.07e-56 yraL - - S - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HMMFCFNL_01537 2.57e-192 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
HMMFCFNL_01538 3.85e-259 yraM - - S - - - PrpF protein
HMMFCFNL_01539 2.44e-209 yraN - - K - - - Transcriptional regulator
HMMFCFNL_01540 5.91e-283 yraO - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
HMMFCFNL_01541 2.43e-239 yrpG - - C - - - Aldo/keto reductase family
HMMFCFNL_01542 1.45e-120 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HMMFCFNL_01543 1.04e-164 zinT - - S ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
HMMFCFNL_01544 2.39e-162 yrpD - - S - - - Domain of unknown function, YrpD
HMMFCFNL_01545 5.43e-185 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
HMMFCFNL_01546 4.23e-246 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
HMMFCFNL_01547 1.64e-28 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
HMMFCFNL_01548 6.68e-159 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
HMMFCFNL_01549 2.01e-118 yrdA - - S - - - DinB family
HMMFCFNL_01550 2.14e-53 - - - - - - - -
HMMFCFNL_01551 2.06e-11 M1-394 - - S - - - Domain of unknown function (DUF4280)
HMMFCFNL_01552 1.04e-71 - - - S - - - Protein of unknown function (DUF2568)
HMMFCFNL_01553 2.11e-130 yrdC - - Q - - - Isochorismatase family
HMMFCFNL_01555 3.11e-289 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
HMMFCFNL_01556 7.91e-55 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
HMMFCFNL_01557 4.82e-103 bkdR - - K - - - helix_turn_helix ASNC type
HMMFCFNL_01558 9.34e-176 azlC - - E - - - AzlC protein
HMMFCFNL_01559 1.97e-66 azlD - - E - - - Branched-chain amino acid transport protein (AzlD)
HMMFCFNL_01560 1.17e-290 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HMMFCFNL_01562 6e-213 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
HMMFCFNL_01563 1.01e-252 trkA - - P ko:K07222 - ko00000 Oxidoreductase
HMMFCFNL_01564 1.64e-202 - - - K - - - Transcriptional regulator
HMMFCFNL_01565 1.16e-214 yrdR - - EG - - - EamA-like transporter family
HMMFCFNL_01566 7.04e-23 - - - S - - - YrzO-like protein
HMMFCFNL_01567 3.27e-294 yrkA - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
HMMFCFNL_01568 2.16e-108 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
HMMFCFNL_01569 2.17e-268 blt - - EGP ko:K08153,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
HMMFCFNL_01570 1.24e-194 bltR - - K - - - helix_turn_helix, mercury resistance
HMMFCFNL_01571 1.01e-134 yrkC - - G - - - Cupin domain
HMMFCFNL_01572 3.32e-28 - - - - - - - -
HMMFCFNL_01573 4.38e-52 yrkD - - S - - - protein conserved in bacteria
HMMFCFNL_01574 1.32e-106 yrkE - - O - - - DsrE/DsrF/DrsH-like family
HMMFCFNL_01575 1.67e-128 yrkF - - OP - - - Belongs to the sulfur carrier protein TusA family
HMMFCFNL_01576 0.000112 perX - - S - - - DsrE/DsrF-like family
HMMFCFNL_01577 2.16e-265 yrkH - - P - - - Rhodanese Homology Domain
HMMFCFNL_01578 6.46e-49 yrkI - - O - - - Belongs to the sulfur carrier protein TusA family
HMMFCFNL_01579 1.29e-165 yrkJ - - S ko:K07090 - ko00000 membrane transporter protein
HMMFCFNL_01580 3.58e-35 - - - S - - - Protein of unknown function with HXXEE motif
HMMFCFNL_01581 3.59e-57 - - - S - - - Protein of unknown function with HXXEE motif
HMMFCFNL_01582 5.71e-126 yrkL - - S ko:K11748 - ko00000,ko02000 Flavodoxin-like fold
HMMFCFNL_01583 3.13e-133 yrkN - - K - - - Acetyltransferase (GNAT) family
HMMFCFNL_01584 1.77e-281 yrkO - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
HMMFCFNL_01585 2.91e-163 yrkP - - T ko:K02483 - ko00000,ko02022 Transcriptional regulator
HMMFCFNL_01586 5.76e-303 yrkQ - - T - - - Histidine kinase
HMMFCFNL_01587 2.15e-90 psiE - - S ko:K13256 - ko00000 Protein PsiE homolog
HMMFCFNL_01588 1.14e-20 - - - L ko:K06400 - ko00000 Recombinase
HMMFCFNL_01589 2.11e-78 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HMMFCFNL_01590 5.74e-38 xkdA - - E - - - IrrE N-terminal-like domain
HMMFCFNL_01592 6.02e-30 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
HMMFCFNL_01595 4.16e-34 - - - S - - - SMI1-KNR4 cell-wall
HMMFCFNL_01596 9.35e-20 - - - - - - - -
HMMFCFNL_01597 9.7e-56 - - - - - - - -
HMMFCFNL_01598 4.37e-20 - - - S - - - SMI1 / KNR4 family
HMMFCFNL_01599 5.52e-37 - - - S - - - SMI1-KNR4 cell-wall
HMMFCFNL_01601 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 nucleic acid phosphodiester bond hydrolysis
HMMFCFNL_01602 2.85e-265 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Aspartate phosphatase response regulator
HMMFCFNL_01604 7.09e-88 - - - K - - - Glyoxalase bleomycin resistance protein dioxygenase
HMMFCFNL_01605 1.97e-198 yybE - - K - - - Transcriptional regulator
HMMFCFNL_01606 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HMMFCFNL_01607 2.67e-38 - - - L ko:K06400 - ko00000 Recombinase
HMMFCFNL_01608 7.53e-161 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HMMFCFNL_01609 2.53e-97 nucB - - M - - - Deoxyribonuclease NucA/NucB
HMMFCFNL_01610 2.12e-167 - - - - - - - -
HMMFCFNL_01611 3.62e-215 yqeC 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconate dehydrogenase
HMMFCFNL_01612 1.89e-134 yqeD - - S - - - SNARE associated Golgi protein
HMMFCFNL_01613 1.68e-176 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
HMMFCFNL_01614 2.24e-182 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
HMMFCFNL_01616 2.17e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
HMMFCFNL_01617 4.78e-273 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HMMFCFNL_01618 8.1e-199 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HMMFCFNL_01619 8.95e-61 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
HMMFCFNL_01620 5.83e-140 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HMMFCFNL_01621 3.95e-132 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
HMMFCFNL_01622 1.39e-81 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HMMFCFNL_01623 6.62e-177 yqeM - - Q - - - Methyltransferase
HMMFCFNL_01624 4.46e-188 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HMMFCFNL_01625 6.38e-136 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
HMMFCFNL_01626 3.25e-137 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
HMMFCFNL_01627 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
HMMFCFNL_01628 2.36e-22 - - - S - - - YqzM-like protein
HMMFCFNL_01629 2.35e-243 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
HMMFCFNL_01630 4e-49 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
HMMFCFNL_01631 9.8e-258 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HMMFCFNL_01632 2.73e-283 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
HMMFCFNL_01633 1.67e-68 yqxA - - S - - - Protein of unknown function (DUF3679)
HMMFCFNL_01634 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HMMFCFNL_01635 9.71e-275 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
HMMFCFNL_01636 1.65e-241 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HMMFCFNL_01637 6.19e-116 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HMMFCFNL_01638 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
HMMFCFNL_01639 3.41e-257 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HMMFCFNL_01640 2.2e-223 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
HMMFCFNL_01641 2.79e-178 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HMMFCFNL_01642 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
HMMFCFNL_01643 4.02e-201 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
HMMFCFNL_01644 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
HMMFCFNL_01645 2.25e-90 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
HMMFCFNL_01646 1.08e-289 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
HMMFCFNL_01647 4.35e-192 yqfA - - S - - - UPF0365 protein
HMMFCFNL_01648 2.57e-78 yqfB - - - - - - -
HMMFCFNL_01649 2.07e-60 yqfC - - S - - - sporulation protein YqfC
HMMFCFNL_01650 4.23e-242 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
HMMFCFNL_01651 4.99e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
HMMFCFNL_01653 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
HMMFCFNL_01654 8.68e-106 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HMMFCFNL_01655 4.75e-80 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
HMMFCFNL_01656 6.71e-93 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HMMFCFNL_01657 9.98e-215 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HMMFCFNL_01658 5.29e-27 - - - S - - - YqzL-like protein
HMMFCFNL_01659 3.56e-185 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
HMMFCFNL_01660 2.12e-222 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
HMMFCFNL_01661 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
HMMFCFNL_01662 3.29e-144 ccpN - - K - - - CBS domain
HMMFCFNL_01663 6.38e-191 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HMMFCFNL_01664 6.03e-114 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
HMMFCFNL_01665 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HMMFCFNL_01666 2.79e-254 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HMMFCFNL_01667 4.62e-81 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
HMMFCFNL_01668 1.63e-148 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
HMMFCFNL_01669 6.25e-268 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HMMFCFNL_01670 1.75e-226 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HMMFCFNL_01671 4.13e-51 yqfQ - - S - - - YqfQ-like protein
HMMFCFNL_01672 1.09e-310 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HMMFCFNL_01673 1.04e-214 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HMMFCFNL_01674 3.01e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
HMMFCFNL_01675 3.83e-199 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
HMMFCFNL_01676 4.98e-106 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
HMMFCFNL_01677 1.37e-140 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
HMMFCFNL_01678 2.04e-81 yqfX - - S - - - membrane
HMMFCFNL_01679 5.22e-257 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HMMFCFNL_01680 1.35e-61 yqfZ - - M ko:K06417 - ko00000 LysM domain
HMMFCFNL_01681 2.74e-168 yqgB - - S - - - Protein of unknown function (DUF1189)
HMMFCFNL_01682 2.36e-100 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
HMMFCFNL_01683 1.59e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
HMMFCFNL_01684 3.96e-293 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
HMMFCFNL_01685 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
HMMFCFNL_01686 2.61e-205 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
HMMFCFNL_01687 7.11e-203 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
HMMFCFNL_01688 1.51e-201 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
HMMFCFNL_01689 9.78e-190 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HMMFCFNL_01690 1.57e-186 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HMMFCFNL_01691 9e-93 yqzC - - S - - - YceG-like family
HMMFCFNL_01692 3.42e-68 yqzD - - - - - - -
HMMFCFNL_01694 2.27e-247 yqgM 2.4.1.250 - M ko:K15521 - ko00000,ko01000 Glycosyl transferases group 1
HMMFCFNL_01695 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HMMFCFNL_01696 2.57e-133 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HMMFCFNL_01697 3.38e-14 yqgO - - - - - - -
HMMFCFNL_01698 0.0 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
HMMFCFNL_01699 1.27e-43 yqgQ - - S - - - Protein conserved in bacteria
HMMFCFNL_01700 2.31e-230 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
HMMFCFNL_01701 0.0 yqgS 2.7.8.20 - M ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
HMMFCFNL_01702 2.05e-281 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
HMMFCFNL_01703 3.82e-256 yqgU - - - - - - -
HMMFCFNL_01704 7.34e-66 yqgV - - S - - - Thiamine-binding protein
HMMFCFNL_01705 1.91e-31 yqgW - - S - - - Protein of unknown function (DUF2759)
HMMFCFNL_01706 1.07e-155 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
HMMFCFNL_01707 1.46e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
HMMFCFNL_01708 7.79e-85 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
HMMFCFNL_01710 8.33e-191 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HMMFCFNL_01711 4.95e-306 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
HMMFCFNL_01712 1.51e-233 yqxL - - P - - - Mg2 transporter protein
HMMFCFNL_01713 7.5e-06 - - - S - - - Domain in cystathionine beta-synthase and other proteins.
HMMFCFNL_01714 2.13e-255 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HMMFCFNL_01715 2.5e-218 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
HMMFCFNL_01716 5.33e-63 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
HMMFCFNL_01717 5.81e-86 gspH - - NU ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02035,ko02044 protein transport across the cell outer membrane
HMMFCFNL_01718 1.77e-78 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
HMMFCFNL_01719 7.11e-47 comGF - - U ko:K02246,ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
HMMFCFNL_01720 1.88e-57 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
HMMFCFNL_01721 2.84e-36 yqzE - - S - - - YqzE-like protein
HMMFCFNL_01722 1.24e-68 yqzG - - S - - - Protein of unknown function (DUF3889)
HMMFCFNL_01723 3.63e-152 yqxM - - - ko:K19433 - ko00000 -
HMMFCFNL_01724 7.4e-98 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
HMMFCFNL_01725 3.14e-182 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
HMMFCFNL_01726 3.69e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
HMMFCFNL_01727 1.39e-33 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
HMMFCFNL_01728 2.07e-193 yqhG - - S - - - Bacterial protein YqhG of unknown function
HMMFCFNL_01729 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
HMMFCFNL_01730 1.35e-261 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
HMMFCFNL_01731 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HMMFCFNL_01732 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HMMFCFNL_01733 7.5e-83 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
HMMFCFNL_01734 1.07e-202 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HMMFCFNL_01735 1.97e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HMMFCFNL_01736 1.21e-210 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
HMMFCFNL_01737 5.18e-81 yqhP - - - - - - -
HMMFCFNL_01738 2.1e-220 yqhQ - - S - - - Protein of unknown function (DUF1385)
HMMFCFNL_01739 8.02e-121 yqhR - - S - - - Conserved membrane protein YqhR
HMMFCFNL_01740 1.17e-101 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
HMMFCFNL_01741 7.05e-248 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
HMMFCFNL_01742 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HMMFCFNL_01743 6.96e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
HMMFCFNL_01744 8.22e-217 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
HMMFCFNL_01745 1.34e-109 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
HMMFCFNL_01746 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
HMMFCFNL_01747 1.93e-77 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
HMMFCFNL_01748 7.65e-257 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
HMMFCFNL_01749 1.28e-131 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
HMMFCFNL_01750 1.08e-148 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
HMMFCFNL_01751 9.92e-135 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
HMMFCFNL_01752 3.21e-93 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HMMFCFNL_01753 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HMMFCFNL_01754 9.55e-88 yqhY - - S - - - protein conserved in bacteria
HMMFCFNL_01755 4.8e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HMMFCFNL_01756 4.34e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HMMFCFNL_01757 2.91e-311 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HMMFCFNL_01758 1.09e-51 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HMMFCFNL_01759 3.45e-208 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HMMFCFNL_01760 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HMMFCFNL_01761 1.77e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
HMMFCFNL_01762 1.53e-102 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
HMMFCFNL_01763 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
HMMFCFNL_01764 5.97e-302 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
HMMFCFNL_01765 1.89e-186 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HMMFCFNL_01767 5.68e-273 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
HMMFCFNL_01768 2.26e-37 - - - - - - - -
HMMFCFNL_01769 1.14e-138 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
HMMFCFNL_01770 5.61e-167 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
HMMFCFNL_01771 1.1e-278 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
HMMFCFNL_01772 3.28e-197 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
HMMFCFNL_01773 1.73e-268 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
HMMFCFNL_01774 1.25e-262 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
HMMFCFNL_01775 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
HMMFCFNL_01776 1.03e-207 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HMMFCFNL_01777 1.56e-46 yqzF - - S - - - Protein of unknown function (DUF2627)
HMMFCFNL_01778 0.0 bkdR - - KT - - - Transcriptional regulator
HMMFCFNL_01779 1.5e-199 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
HMMFCFNL_01780 1.92e-262 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
HMMFCFNL_01781 4.82e-255 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
HMMFCFNL_01782 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HMMFCFNL_01783 1.11e-237 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HMMFCFNL_01784 6.92e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HMMFCFNL_01785 1.64e-282 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HMMFCFNL_01786 6.38e-195 - - - K ko:K19575 - ko00000,ko00002,ko03000 helix_turn_helix, mercury resistance
HMMFCFNL_01787 3.09e-267 norA - - EGP ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
HMMFCFNL_01788 9.96e-213 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HMMFCFNL_01789 3.79e-101 yqiW - - S - - - Belongs to the UPF0403 family
HMMFCFNL_01790 1.43e-175 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
HMMFCFNL_01791 8.94e-143 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
HMMFCFNL_01792 1.49e-165 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
HMMFCFNL_01793 1.73e-221 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
HMMFCFNL_01794 3.43e-128 yqjB - - S - - - protein conserved in bacteria
HMMFCFNL_01796 5.45e-94 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
HMMFCFNL_01797 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HMMFCFNL_01798 5.26e-259 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
HMMFCFNL_01799 1.57e-177 yqjF - - S ko:K09166 - ko00000 Uncharacterized conserved protein (COG2071)
HMMFCFNL_01800 3.36e-184 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HMMFCFNL_01801 1.77e-32 yqzJ - - - - - - -
HMMFCFNL_01802 5.04e-297 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HMMFCFNL_01803 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HMMFCFNL_01804 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HMMFCFNL_01805 4.25e-219 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HMMFCFNL_01806 8.59e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HMMFCFNL_01807 6.4e-187 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HMMFCFNL_01808 1.21e-245 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HMMFCFNL_01809 0.0 rocB - - E - - - arginine degradation protein
HMMFCFNL_01810 3.25e-188 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HMMFCFNL_01811 6.6e-229 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
HMMFCFNL_01812 2.31e-183 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
HMMFCFNL_01813 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
HMMFCFNL_01814 6.6e-229 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
HMMFCFNL_01815 1.82e-93 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HMMFCFNL_01817 1.38e-287 yqjV - - G - - - Major Facilitator Superfamily
HMMFCFNL_01819 4.03e-304 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HMMFCFNL_01820 3.23e-66 yqiX - - S - - - YolD-like protein
HMMFCFNL_01821 5.46e-113 yqjY - - K ko:K06977 - ko00000 acetyltransferase
HMMFCFNL_01822 6.7e-73 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
HMMFCFNL_01823 4.59e-248 yqkA - - K - - - GrpB protein
HMMFCFNL_01824 6.17e-73 yqkB - - S - - - Belongs to the HesB IscA family
HMMFCFNL_01825 1.12e-53 yqkC - - S - - - Protein of unknown function (DUF2552)
HMMFCFNL_01826 3.79e-219 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
HMMFCFNL_01827 6.61e-26 yqkE - - S - - - Protein of unknown function (DUF3886)
HMMFCFNL_01828 1.04e-214 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
HMMFCFNL_01829 8.21e-10 - - - S - - - Protein of unknown function (DUF3936)
HMMFCFNL_01830 4.07e-120 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
HMMFCFNL_01831 2.93e-280 yqxK - - L - - - DNA helicase
HMMFCFNL_01832 3.18e-77 ansR - - K - - - Transcriptional regulator
HMMFCFNL_01833 1.77e-238 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
HMMFCFNL_01834 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
HMMFCFNL_01835 1.14e-309 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
HMMFCFNL_01836 2.78e-309 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
HMMFCFNL_01837 7.27e-42 yqkK - - - - - - -
HMMFCFNL_01838 1.96e-139 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
HMMFCFNL_01839 2.26e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
HMMFCFNL_01840 2.25e-49 - - - S - - - Protein of unknown function (DUF4227)
HMMFCFNL_01841 4.57e-213 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
HMMFCFNL_01842 2.77e-293 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
HMMFCFNL_01843 1.39e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HMMFCFNL_01844 5.58e-270 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HMMFCFNL_01845 3e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
HMMFCFNL_01846 6.78e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HMMFCFNL_01847 1.18e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HMMFCFNL_01848 1.15e-143 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
HMMFCFNL_01849 5.43e-90 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
HMMFCFNL_01850 6.71e-102 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
HMMFCFNL_01851 6.02e-246 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
HMMFCFNL_01852 2.15e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
HMMFCFNL_01853 1.85e-143 - - - S ko:K06407 - ko00000 stage V sporulation protein
HMMFCFNL_01854 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
HMMFCFNL_01855 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HMMFCFNL_01856 1.8e-191 ypuA - - S - - - Secreted protein
HMMFCFNL_01857 1.23e-105 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HMMFCFNL_01863 4.28e-42 - - - S - - - Pfam Transposase IS66
HMMFCFNL_01864 1.5e-33 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HMMFCFNL_01866 1.02e-42 ypzJ - - S ko:K07069 - ko00000 nucleic-acid-binding protein containing a Zn-ribbon domain
HMMFCFNL_01867 5.82e-126 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HMMFCFNL_01868 5.98e-72 ypuD - - - - - - -
HMMFCFNL_01869 5.92e-260 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HMMFCFNL_01870 2.5e-147 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
HMMFCFNL_01871 2.1e-290 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HMMFCFNL_01872 8.41e-107 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HMMFCFNL_01873 1.12e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HMMFCFNL_01874 1.19e-118 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
HMMFCFNL_01875 3.82e-167 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HMMFCFNL_01876 1.65e-134 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HMMFCFNL_01877 2.92e-126 ypuI - - S - - - Protein of unknown function (DUF3907)
HMMFCFNL_01878 1.18e-272 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HMMFCFNL_01879 7.57e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
HMMFCFNL_01880 8.62e-114 spmB - - S ko:K06374 - ko00000 Spore maturation protein
HMMFCFNL_01881 4.45e-169 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HMMFCFNL_01882 1.5e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HMMFCFNL_01883 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
HMMFCFNL_01884 2.7e-278 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HMMFCFNL_01885 1.69e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HMMFCFNL_01886 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HMMFCFNL_01887 1.08e-133 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HMMFCFNL_01888 5.59e-236 rsiX - - - - - - -
HMMFCFNL_01889 6.26e-170 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HMMFCFNL_01890 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMMFCFNL_01891 3.07e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HMMFCFNL_01892 8.35e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
HMMFCFNL_01893 8.28e-251 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
HMMFCFNL_01894 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
HMMFCFNL_01895 3.55e-128 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
HMMFCFNL_01896 1e-141 ypbE - - M - - - Lysin motif
HMMFCFNL_01897 1.42e-106 ypbF - - S - - - Protein of unknown function (DUF2663)
HMMFCFNL_01898 4.33e-188 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
HMMFCFNL_01899 5.56e-136 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HMMFCFNL_01900 1.42e-308 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
HMMFCFNL_01901 5.29e-224 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
HMMFCFNL_01902 1.76e-153 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
HMMFCFNL_01903 6.93e-208 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
HMMFCFNL_01904 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
HMMFCFNL_01905 1.04e-140 ypfA - - M - - - Flagellar protein YcgR
HMMFCFNL_01906 1.39e-29 - - - S - - - Family of unknown function (DUF5359)
HMMFCFNL_01907 7.9e-144 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
HMMFCFNL_01908 7.8e-262 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
HMMFCFNL_01909 1.14e-235 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HMMFCFNL_01910 1.13e-11 - - - S - - - YpzI-like protein
HMMFCFNL_01911 1.3e-132 yphA - - - - - - -
HMMFCFNL_01912 4.35e-207 yphB - - S ko:K05739 - ko00000 YIEGIA protein
HMMFCFNL_01913 5.91e-38 ypzH - - - - - - -
HMMFCFNL_01914 1.72e-315 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
HMMFCFNL_01915 1.05e-229 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
HMMFCFNL_01916 7.09e-27 yphE - - S - - - Protein of unknown function (DUF2768)
HMMFCFNL_01917 4.31e-176 yphF - - - - - - -
HMMFCFNL_01918 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HMMFCFNL_01919 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HMMFCFNL_01920 4.41e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
HMMFCFNL_01921 5.13e-46 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
HMMFCFNL_01922 7.17e-177 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
HMMFCFNL_01923 1.34e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HMMFCFNL_01924 4.09e-249 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HMMFCFNL_01925 2.17e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HMMFCFNL_01926 2.49e-181 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
HMMFCFNL_01927 1.44e-277 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HMMFCFNL_01928 2.23e-260 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HMMFCFNL_01929 9.82e-84 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
HMMFCFNL_01930 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HMMFCFNL_01931 4.1e-228 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HMMFCFNL_01932 4.88e-144 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
HMMFCFNL_01933 2.6e-149 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
HMMFCFNL_01934 8.95e-293 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HMMFCFNL_01935 2.21e-185 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HMMFCFNL_01936 1.83e-258 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HMMFCFNL_01937 1.21e-264 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
HMMFCFNL_01938 6.68e-300 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HMMFCFNL_01939 1.02e-296 ypiA - - S - - - COG0457 FOG TPR repeat
HMMFCFNL_01940 7.45e-129 ypiB - - S - - - Belongs to the UPF0302 family
HMMFCFNL_01941 5.55e-100 ypiF - - S - - - Protein of unknown function (DUF2487)
HMMFCFNL_01942 3.35e-126 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
HMMFCFNL_01943 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
HMMFCFNL_01944 5.71e-191 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
HMMFCFNL_01945 1.15e-125 ypjA - - S - - - membrane
HMMFCFNL_01946 1.8e-178 ypjB - - S - - - sporulation protein
HMMFCFNL_01947 3.7e-200 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
HMMFCFNL_01948 1.01e-73 ypjD - - S - - - Nucleotide pyrophosphohydrolase
HMMFCFNL_01949 2.4e-189 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HMMFCFNL_01950 2.52e-93 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
HMMFCFNL_01951 1.89e-166 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
HMMFCFNL_01952 1.41e-266 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
HMMFCFNL_01953 1.06e-278 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HMMFCFNL_01954 4.87e-234 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HMMFCFNL_01955 4.85e-194 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HMMFCFNL_01956 5.47e-200 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HMMFCFNL_01957 4.16e-85 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HMMFCFNL_01958 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
HMMFCFNL_01959 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
HMMFCFNL_01960 2.66e-102 ypmB - - S - - - protein conserved in bacteria
HMMFCFNL_01961 4.37e-285 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
HMMFCFNL_01962 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
HMMFCFNL_01963 6.62e-165 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
HMMFCFNL_01964 3.57e-158 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HMMFCFNL_01965 1.37e-119 ypoC - - - - - - -
HMMFCFNL_01966 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HMMFCFNL_01967 1.3e-149 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HMMFCFNL_01968 1.4e-235 yppC - - S - - - Protein of unknown function (DUF2515)
HMMFCFNL_01971 1.42e-10 yppE - - S - - - Bacterial domain of unknown function (DUF1798)
HMMFCFNL_01972 9.21e-11 - - - S - - - YppF-like protein
HMMFCFNL_01973 8.72e-68 yppG - - S - - - YppG-like protein
HMMFCFNL_01974 1.19e-92 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HMMFCFNL_01975 1.85e-110 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
HMMFCFNL_01976 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HMMFCFNL_01977 2.41e-299 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
HMMFCFNL_01978 5.9e-129 ypsA - - S - - - Belongs to the UPF0398 family
HMMFCFNL_01979 2.97e-60 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HMMFCFNL_01980 1.16e-285 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
HMMFCFNL_01982 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
HMMFCFNL_01983 4.63e-176 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HMMFCFNL_01984 2.96e-203 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HMMFCFNL_01985 7.8e-238 kdgR - - K ko:K02525 - ko00000,ko03000 transcriptional
HMMFCFNL_01986 2.83e-237 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
HMMFCFNL_01987 1.2e-131 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
HMMFCFNL_01988 9.61e-223 kdgT - - P ko:K02526 - ko00000,ko02000 The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
HMMFCFNL_01989 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HMMFCFNL_01990 9.13e-126 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HMMFCFNL_01991 4.98e-291 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
HMMFCFNL_01992 2.63e-265 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
HMMFCFNL_01993 3.33e-113 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
HMMFCFNL_01994 0.0 ypbR - - S - - - Dynamin family
HMMFCFNL_01995 6.77e-51 ypbS - - S - - - Protein of unknown function (DUF2533)
HMMFCFNL_01996 1.08e-11 - - - - - - - -
HMMFCFNL_01997 2.26e-213 ypcP - - L - - - 5'3' exonuclease
HMMFCFNL_01998 5.23e-05 - - - - ko:K06429 - ko00000 -
HMMFCFNL_01999 7.64e-88 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
HMMFCFNL_02000 2.12e-155 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HMMFCFNL_02001 1.1e-160 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
HMMFCFNL_02002 1.54e-37 ypeQ - - S - - - Zinc-finger
HMMFCFNL_02003 1.5e-40 - - - S - - - Protein of unknown function (DUF2564)
HMMFCFNL_02004 1.17e-22 degR - - - - - - -
HMMFCFNL_02005 5.12e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
HMMFCFNL_02006 4.28e-275 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
HMMFCFNL_02007 6.09e-225 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HMMFCFNL_02008 3.13e-114 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
HMMFCFNL_02009 2.07e-141 yagB - - S ko:K06950 - ko00000 phosphohydrolase
HMMFCFNL_02010 2.32e-203 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
HMMFCFNL_02011 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
HMMFCFNL_02012 9.69e-99 yphP - - S - - - Belongs to the UPF0403 family
HMMFCFNL_02013 1.97e-183 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
HMMFCFNL_02014 8.17e-147 ypjP - - S - - - YpjP-like protein
HMMFCFNL_02015 8.91e-121 ltrC 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
HMMFCFNL_02016 9.58e-122 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HMMFCFNL_02017 2.33e-143 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HMMFCFNL_02018 8.03e-143 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
HMMFCFNL_02019 2.23e-233 yplP - - K - - - Transcriptional regulator
HMMFCFNL_02020 1.04e-309 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HMMFCFNL_02021 2.12e-53 ypmP - - S - - - Protein of unknown function (DUF2535)
HMMFCFNL_02022 7.93e-140 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
HMMFCFNL_02023 2.58e-178 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
HMMFCFNL_02024 5.59e-128 ypmS - - S - - - protein conserved in bacteria
HMMFCFNL_02025 8.69e-40 ypmT - - S - - - Uncharacterized ympT
HMMFCFNL_02026 7.03e-290 mepA - - V - - - MATE efflux family protein
HMMFCFNL_02027 4.14e-94 ypoP - - K - - - transcriptional
HMMFCFNL_02028 9.83e-133 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HMMFCFNL_02029 4.13e-102 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
HMMFCFNL_02030 2.36e-157 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
HMMFCFNL_02031 1.9e-278 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
HMMFCFNL_02032 1.89e-227 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
HMMFCFNL_02033 3.1e-83 cgeA - - - ko:K06319 - ko00000 -
HMMFCFNL_02034 1.06e-59 cgeC - - - ko:K06321 - ko00000 -
HMMFCFNL_02035 0.0 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
HMMFCFNL_02036 3.27e-183 yiiD - - K ko:K06323 - ko00000 acetyltransferase
HMMFCFNL_02038 5.62e-316 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HMMFCFNL_02039 5.65e-160 atoD 2.8.3.8, 2.8.3.9 - I ko:K01034 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HMMFCFNL_02040 9.44e-153 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HMMFCFNL_02041 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
HMMFCFNL_02042 5.27e-197 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
HMMFCFNL_02043 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
HMMFCFNL_02044 1.4e-62 yokU - - S - - - YokU-like protein, putative antitoxin
HMMFCFNL_02045 7.3e-50 yozE - - S - - - Belongs to the UPF0346 family
HMMFCFNL_02046 7.44e-159 yodN - - - - - - -
HMMFCFNL_02048 5.18e-34 yozD - - S - - - YozD-like protein
HMMFCFNL_02049 4.02e-138 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
HMMFCFNL_02050 1.17e-71 yodL - - S - - - YodL-like
HMMFCFNL_02051 2.08e-12 - - - - - - - -
HMMFCFNL_02052 1.68e-163 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
HMMFCFNL_02053 1.33e-189 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
HMMFCFNL_02054 4.86e-41 yodI - - - - - - -
HMMFCFNL_02055 3.03e-166 yodH - - Q - - - Methyltransferase
HMMFCFNL_02056 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
HMMFCFNL_02057 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HMMFCFNL_02058 2.36e-38 - - - S - - - Protein of unknown function (DUF3311)
HMMFCFNL_02059 1.38e-222 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
HMMFCFNL_02060 1.31e-146 yahD - - S ko:K06999 - ko00000 Carboxylesterase
HMMFCFNL_02061 4.53e-139 yodC - - C - - - nitroreductase
HMMFCFNL_02062 2.63e-73 yodB - - K - - - transcriptional
HMMFCFNL_02063 3.97e-84 iolK - - S - - - tautomerase
HMMFCFNL_02064 9.24e-290 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
HMMFCFNL_02065 1.95e-14 - - - - - - - -
HMMFCFNL_02066 2.88e-103 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
HMMFCFNL_02067 1.92e-206 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
HMMFCFNL_02068 6.21e-57 - - - - - - - -
HMMFCFNL_02069 2.32e-79 yojF - - S - - - Protein of unknown function (DUF1806)
HMMFCFNL_02070 3.71e-161 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
HMMFCFNL_02071 2.39e-192 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HMMFCFNL_02072 2.06e-313 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
HMMFCFNL_02074 3.54e-140 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HMMFCFNL_02075 1.13e-293 yojK - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
HMMFCFNL_02076 8.74e-266 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
HMMFCFNL_02077 7.31e-142 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HMMFCFNL_02078 1.33e-207 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
HMMFCFNL_02079 0.0 yojO - - P - - - Von Willebrand factor
HMMFCFNL_02080 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HMMFCFNL_02081 3.02e-263 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HMMFCFNL_02082 1.35e-213 yocS - - S ko:K03453 - ko00000 -transporter
HMMFCFNL_02083 4.35e-300 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HMMFCFNL_02084 3.91e-211 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
HMMFCFNL_02085 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
HMMFCFNL_02086 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HMMFCFNL_02087 1.91e-42 yozC - - - - - - -
HMMFCFNL_02088 2.17e-74 yozO - - S - - - Bacterial PH domain
HMMFCFNL_02089 1.83e-49 yocN - - - - - - -
HMMFCFNL_02090 2.94e-55 yozN - - - - - - -
HMMFCFNL_02091 2.21e-113 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HMMFCFNL_02092 2.67e-39 - - - - - - - -
HMMFCFNL_02093 3.02e-70 yocL - - - - - - -
HMMFCFNL_02094 4.07e-107 yocK - - T - - - general stress protein
HMMFCFNL_02095 1.46e-147 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HMMFCFNL_02096 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
HMMFCFNL_02097 3.92e-173 yocH - - M - - - COG1388 FOG LysM repeat
HMMFCFNL_02098 4.71e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HMMFCFNL_02099 4.09e-251 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HMMFCFNL_02100 2.31e-257 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
HMMFCFNL_02101 4.53e-239 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
HMMFCFNL_02102 1.32e-122 yocC - - - - - - -
HMMFCFNL_02103 2.6e-185 - - - - - - - -
HMMFCFNL_02104 3.97e-119 yozB - - S ko:K08976 - ko00000 membrane
HMMFCFNL_02105 9.39e-157 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HMMFCFNL_02106 8.12e-69 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
HMMFCFNL_02107 5.2e-121 yobW - - - - - - -
HMMFCFNL_02108 5.81e-222 yobV - - K - - - WYL domain
HMMFCFNL_02109 8.64e-112 - - - K - - - Bacterial transcription activator, effector binding domain
HMMFCFNL_02110 4.49e-168 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
HMMFCFNL_02111 1.53e-127 yobS - - K - - - Transcriptional regulator
HMMFCFNL_02112 7.42e-176 - - - J - - - FR47-like protein
HMMFCFNL_02113 1.38e-170 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
HMMFCFNL_02114 1.75e-69 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
HMMFCFNL_02115 0.0 iaaM 1.4.3.4 - E ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 ko00000,ko00001,ko00002,ko01000 COG1231 Monoamine oxidase
HMMFCFNL_02116 1.33e-130 yokH - - G - - - SMI1 / KNR4 family
HMMFCFNL_02117 2.81e-21 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HMMFCFNL_02118 1.91e-34 dinB2 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HMMFCFNL_02119 1.95e-26 - - - - - - - -
HMMFCFNL_02121 7.88e-135 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
HMMFCFNL_02123 9.95e-23 - - - - - - - -
HMMFCFNL_02124 3.23e-86 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
HMMFCFNL_02126 6.26e-152 - - - - - - - -
HMMFCFNL_02127 1.74e-14 - - - - - - - -
HMMFCFNL_02128 2.11e-49 - - - S - - - TM2 domain
HMMFCFNL_02129 7.53e-157 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
HMMFCFNL_02130 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
HMMFCFNL_02133 3.77e-217 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
HMMFCFNL_02134 2.07e-148 lin0465 - - S - - - DJ-1/PfpI family
HMMFCFNL_02135 2.68e-100 yoaW - - - - - - -
HMMFCFNL_02136 8.71e-200 yoaV - - EG - - - EamA-like transporter family
HMMFCFNL_02137 5.48e-202 yoaU - - K - - - LysR substrate binding domain
HMMFCFNL_02138 9.84e-192 yoaT - - S - - - Protein of unknown function (DUF817)
HMMFCFNL_02139 7.19e-41 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
HMMFCFNL_02140 9.24e-98 yoaS - - S - - - Protein of unknown function (DUF2975)
HMMFCFNL_02141 2.68e-217 yoaR - - V - - - vancomycin resistance protein
HMMFCFNL_02142 7.6e-113 - - - - - - - -
HMMFCFNL_02143 1.42e-25 yoaP - - K - - - YoaP-like
HMMFCFNL_02145 1.79e-292 oxdD 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
HMMFCFNL_02148 5.08e-171 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
HMMFCFNL_02149 5e-253 - 4.2.2.10 - G ko:K01732 - ko00000,ko01000 Amb_all
HMMFCFNL_02150 1.79e-145 yoaK - - S - - - Membrane
HMMFCFNL_02151 2.61e-171 yoaJ - - G ko:K20628 - ko00000 Endoglucanase C-terminal domain subunit and related proteins
HMMFCFNL_02152 0.0 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
HMMFCFNL_02153 1.36e-283 yoaH - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 methyl-accepting chemotaxis protein
HMMFCFNL_02154 2.99e-55 - - - S - - - Protein of unknown function (DUF4025)
HMMFCFNL_02155 1.46e-19 - - - - - - - -
HMMFCFNL_02157 1.25e-45 yoaF - - - - - - -
HMMFCFNL_02158 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HMMFCFNL_02159 3.36e-234 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMMFCFNL_02160 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
HMMFCFNL_02161 6.14e-298 yoaB - - EGP - - - the major facilitator superfamily
HMMFCFNL_02162 1.9e-121 yoaA 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HMMFCFNL_02163 4.08e-171 yoxB - - - - - - -
HMMFCFNL_02164 6.37e-50 yoxC - - S - - - Bacterial protein of unknown function (DUF948)
HMMFCFNL_02165 2.28e-159 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
HMMFCFNL_02166 5.37e-79 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
HMMFCFNL_02167 2.72e-185 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HMMFCFNL_02168 1.29e-259 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HMMFCFNL_02169 2.61e-205 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
HMMFCFNL_02170 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
HMMFCFNL_02171 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HMMFCFNL_02172 4.18e-237 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HMMFCFNL_02173 1.69e-198 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
HMMFCFNL_02174 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
HMMFCFNL_02175 3.31e-47 yoeD - - G - - - Helix-turn-helix domain
HMMFCFNL_02176 1.14e-124 - - - L - - - Integrase
HMMFCFNL_02178 5.87e-127 yoeB - - S - - - IseA DL-endopeptidase inhibitor
HMMFCFNL_02179 9.8e-313 yoeA - - V - - - MATE efflux family protein
HMMFCFNL_02180 1.92e-240 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
HMMFCFNL_02181 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
HMMFCFNL_02191 1.5e-183 spo0M - - S ko:K06377 - ko00000 COG4326 Sporulation control protein
HMMFCFNL_02192 1.58e-36 - - - - - - - -
HMMFCFNL_02193 8.12e-157 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
HMMFCFNL_02194 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HMMFCFNL_02196 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
HMMFCFNL_02197 9.01e-179 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HMMFCFNL_02198 6.93e-217 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
HMMFCFNL_02199 8.33e-190 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HMMFCFNL_02200 1.55e-274 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
HMMFCFNL_02202 4.82e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HMMFCFNL_02203 5.19e-98 ygaO - - - - - - -
HMMFCFNL_02204 1.48e-39 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
HMMFCFNL_02206 6.43e-146 yhzB - - S - - - B3/4 domain
HMMFCFNL_02207 1.2e-283 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HMMFCFNL_02208 9.27e-224 yhbB - - S - - - Putative amidase domain
HMMFCFNL_02209 1.08e-111 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HMMFCFNL_02210 3.4e-143 yhbD - - K - - - Protein of unknown function (DUF4004)
HMMFCFNL_02211 1.32e-95 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
HMMFCFNL_02212 9.07e-107 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
HMMFCFNL_02213 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
HMMFCFNL_02214 1.21e-286 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
HMMFCFNL_02215 1.29e-101 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
HMMFCFNL_02216 2.67e-133 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
HMMFCFNL_02217 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
HMMFCFNL_02218 4.87e-128 yhcB 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 Belongs to the WrbA family
HMMFCFNL_02219 1.13e-58 yhcC - - - - - - -
HMMFCFNL_02220 2.06e-69 - - - - - - - -
HMMFCFNL_02221 1.67e-79 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
HMMFCFNL_02222 7.32e-153 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HMMFCFNL_02223 1.25e-210 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HMMFCFNL_02224 1.64e-210 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HMMFCFNL_02225 1.91e-42 cspB - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
HMMFCFNL_02226 4.49e-194 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
HMMFCFNL_02227 3.36e-249 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
HMMFCFNL_02228 2.62e-301 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HMMFCFNL_02229 1.39e-113 - - - S - - - Protein of unknown function (DUF2812)
HMMFCFNL_02230 3.22e-65 - - - K - - - Transcriptional regulator PadR-like family
HMMFCFNL_02231 1.09e-61 yhcM - - - - - - -
HMMFCFNL_02232 9.32e-108 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HMMFCFNL_02233 2.29e-226 yhcP - - - - - - -
HMMFCFNL_02234 1.68e-146 yhcQ - - M - - - Spore coat protein
HMMFCFNL_02235 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HMMFCFNL_02236 5.1e-134 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
HMMFCFNL_02237 4.78e-218 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
HMMFCFNL_02238 1.74e-88 yhcU - - S - - - Family of unknown function (DUF5365)
HMMFCFNL_02239 1.76e-90 yhcV - - S - - - COG0517 FOG CBS domain
HMMFCFNL_02240 2.5e-154 yhcW - - S ko:K07025 - ko00000 hydrolase
HMMFCFNL_02241 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HMMFCFNL_02242 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HMMFCFNL_02243 5.35e-135 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HMMFCFNL_02244 5.7e-196 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HMMFCFNL_02245 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HMMFCFNL_02246 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HMMFCFNL_02247 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
HMMFCFNL_02248 1.88e-272 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
HMMFCFNL_02249 7.73e-144 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HMMFCFNL_02250 1.34e-115 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
HMMFCFNL_02251 1.65e-51 yhdB - - S - - - YhdB-like protein
HMMFCFNL_02252 1.02e-71 yhdC - - S - - - Protein of unknown function (DUF3889)
HMMFCFNL_02253 2.86e-271 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
HMMFCFNL_02254 1.95e-99 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
HMMFCFNL_02255 2.5e-305 ygxB - - M - - - Conserved TM helix
HMMFCFNL_02256 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
HMMFCFNL_02257 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
HMMFCFNL_02258 7.21e-204 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
HMMFCFNL_02259 4.93e-210 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
HMMFCFNL_02260 3.05e-260 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
HMMFCFNL_02261 5.51e-206 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HMMFCFNL_02262 3.58e-316 yhdG - - E ko:K03294 - ko00000 amino acid
HMMFCFNL_02263 1.01e-308 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HMMFCFNL_02264 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HMMFCFNL_02265 1.75e-100 - - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HMMFCFNL_02266 4.27e-59 yhdK - - S - - - Sigma-M inhibitor protein
HMMFCFNL_02267 1.02e-256 yhdL - - S - - - Sigma factor regulator N-terminal
HMMFCFNL_02268 3.24e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HMMFCFNL_02269 6.74e-244 yhdN - - C - - - Aldo keto reductase
HMMFCFNL_02270 2.26e-142 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HMMFCFNL_02271 2.18e-304 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
HMMFCFNL_02272 3.44e-97 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
HMMFCFNL_02273 5.1e-284 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
HMMFCFNL_02274 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
HMMFCFNL_02275 2.04e-65 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HMMFCFNL_02276 5.83e-87 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HMMFCFNL_02277 1.82e-172 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
HMMFCFNL_02278 3.7e-09 yhdX - - S - - - Uncharacterized protein YhdX
HMMFCFNL_02279 9.73e-239 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
HMMFCFNL_02280 3.28e-177 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HMMFCFNL_02281 1.01e-193 nodB1 - - G - - - deacetylase
HMMFCFNL_02282 3.16e-197 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HMMFCFNL_02283 8.48e-302 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
HMMFCFNL_02284 1.78e-107 nhaX - - T - - - Belongs to the universal stress protein A family
HMMFCFNL_02285 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HMMFCFNL_02286 0.0 yheH - - V ko:K06147,ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HMMFCFNL_02287 9.1e-141 yheG - - GM - - - NAD(P)H-binding
HMMFCFNL_02288 1.25e-38 sspB - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
HMMFCFNL_02289 2.27e-49 yheE - - S - - - Family of unknown function (DUF5342)
HMMFCFNL_02290 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
HMMFCFNL_02291 1.32e-273 yheC - - HJ - - - YheC/D like ATP-grasp
HMMFCFNL_02292 5.9e-259 yheB - - S - - - Belongs to the UPF0754 family
HMMFCFNL_02293 7.46e-72 yheA - - S - - - Belongs to the UPF0342 family
HMMFCFNL_02294 2.61e-261 yhaZ - - L - - - DNA alkylation repair enzyme
HMMFCFNL_02295 8.7e-198 yhaX - - S - - - haloacid dehalogenase-like hydrolase
HMMFCFNL_02296 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
HMMFCFNL_02297 2.63e-267 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
HMMFCFNL_02298 6.51e-114 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
HMMFCFNL_02300 1.79e-169 yhaR - - I - - - enoyl-CoA hydratase
HMMFCFNL_02301 9.36e-36 - - - S - - - YhzD-like protein
HMMFCFNL_02302 1.86e-213 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HMMFCFNL_02303 5.14e-272 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
HMMFCFNL_02304 6.37e-299 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
HMMFCFNL_02305 0.0 yhaN - - L - - - AAA domain
HMMFCFNL_02306 5.22e-228 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
HMMFCFNL_02307 1.88e-39 yhaL - - S - - - Sporulation protein YhaL
HMMFCFNL_02308 6.9e-160 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HMMFCFNL_02309 1.4e-116 yhaK - - S - - - Putative zincin peptidase
HMMFCFNL_02310 8.48e-73 yhaI - - S - - - Protein of unknown function (DUF1878)
HMMFCFNL_02311 4.92e-148 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
HMMFCFNL_02312 3.89e-54 yhaH - - S - - - YtxH-like protein
HMMFCFNL_02313 9.66e-30 - - - - - - - -
HMMFCFNL_02314 6.32e-104 trpP - - S - - - Tryptophan transporter TrpP
HMMFCFNL_02315 1.84e-262 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HMMFCFNL_02316 3.5e-106 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HMMFCFNL_02317 2.7e-176 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
HMMFCFNL_02318 3.63e-271 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
HMMFCFNL_02319 3.37e-160 ecsC - - S - - - EcsC protein family
HMMFCFNL_02320 6.27e-291 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HMMFCFNL_02321 7.4e-310 yhfA - - C - - - membrane
HMMFCFNL_02322 1e-44 - - - C - - - Rubrerythrin
HMMFCFNL_02323 1.31e-118 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
HMMFCFNL_02324 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HMMFCFNL_02325 1.76e-257 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HMMFCFNL_02326 3.99e-230 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
HMMFCFNL_02327 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HMMFCFNL_02328 1.59e-129 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
HMMFCFNL_02329 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
HMMFCFNL_02330 1.25e-236 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HMMFCFNL_02331 3.8e-177 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
HMMFCFNL_02332 1.55e-252 yhfE - - G - - - peptidase M42
HMMFCFNL_02333 1.53e-93 - - - S - - - ASCH
HMMFCFNL_02334 4.77e-289 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HMMFCFNL_02335 3.43e-182 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
HMMFCFNL_02336 1.66e-244 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
HMMFCFNL_02337 8.31e-141 yhfK - - GM - - - NmrA-like family
HMMFCFNL_02338 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
HMMFCFNL_02339 3.94e-85 yhfM - - - - - - -
HMMFCFNL_02340 2.01e-301 yhfN - - O - - - Peptidase M48
HMMFCFNL_02341 1.7e-260 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HMMFCFNL_02342 1.53e-102 - - - K - - - acetyltransferase
HMMFCFNL_02343 1.33e-229 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
HMMFCFNL_02344 3.23e-222 yhfQ - - M ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
HMMFCFNL_02345 9.64e-141 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
HMMFCFNL_02346 4.86e-240 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
HMMFCFNL_02347 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
HMMFCFNL_02348 1.47e-118 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
HMMFCFNL_02349 7.51e-260 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
HMMFCFNL_02350 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
HMMFCFNL_02351 7.82e-204 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HMMFCFNL_02352 9.84e-45 yhzC - - S - - - IDEAL
HMMFCFNL_02353 6.29e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
HMMFCFNL_02354 6.01e-215 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
HMMFCFNL_02355 4.64e-53 yhjA - - S - - - Excalibur calcium-binding domain
HMMFCFNL_02356 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HMMFCFNL_02357 1.61e-36 yhjC - - S - - - Protein of unknown function (DUF3311)
HMMFCFNL_02358 4.13e-78 yhjD - - - - - - -
HMMFCFNL_02359 4.87e-141 yhjE - - S - - - SNARE associated Golgi protein
HMMFCFNL_02360 3.09e-118 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HMMFCFNL_02361 0.0 yhjG - - CH - - - FAD binding domain
HMMFCFNL_02362 2.82e-122 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
HMMFCFNL_02363 8.57e-271 glcP - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
HMMFCFNL_02364 2.69e-255 - 1.1.1.18, 1.1.1.361, 1.1.1.369 - S ko:K00010,ko:K18652 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
HMMFCFNL_02365 5.31e-205 ntdB 3.1.3.24, 3.1.3.92 - S ko:K07024,ko:K18654 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose-6F-phosphate phosphohydrolase
HMMFCFNL_02366 0.0 - 2.6.1.104 - E ko:K18653 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
HMMFCFNL_02367 5.09e-238 yhjM - - K - - - Transcriptional regulator
HMMFCFNL_02368 2.05e-258 yhjN - - S ko:K07120 - ko00000 membrane
HMMFCFNL_02369 1.02e-262 - - - EGP - - - Transmembrane secretion effector
HMMFCFNL_02370 0.0 - - - S - - - Sugar transport-related sRNA regulator N-term
HMMFCFNL_02371 3.85e-72 yhjQ - - C - - - COG1145 Ferredoxin
HMMFCFNL_02372 9.3e-102 yhjR - - S - - - Rubrerythrin
HMMFCFNL_02373 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
HMMFCFNL_02374 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
HMMFCFNL_02375 3.84e-278 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HMMFCFNL_02376 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
HMMFCFNL_02377 2.61e-64 yisB - - V - - - COG1403 Restriction endonuclease
HMMFCFNL_02378 3.3e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
HMMFCFNL_02379 1.12e-85 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
HMMFCFNL_02380 6.07e-33 gerPD - - S ko:K06302 - ko00000 Spore germination protein
HMMFCFNL_02381 3.34e-92 gerPC - - S ko:K06301 - ko00000 Spore germination protein
HMMFCFNL_02382 3.87e-42 gerPB - - S ko:K06300 - ko00000 cell differentiation
HMMFCFNL_02383 1.82e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
HMMFCFNL_02384 1.52e-32 yisI - - S - - - Spo0E like sporulation regulatory protein
HMMFCFNL_02385 4.25e-219 cotH - - M ko:K06330 - ko00000 Spore Coat
HMMFCFNL_02386 2.66e-219 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HMMFCFNL_02387 1.02e-74 yisL - - S - - - UPF0344 protein
HMMFCFNL_02388 0.0 wprA - - O ko:K13274 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HMMFCFNL_02389 8.67e-131 yisN - - S - - - Protein of unknown function (DUF2777)
HMMFCFNL_02390 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
HMMFCFNL_02391 3.27e-159 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
HMMFCFNL_02392 2.91e-310 yisQ - - V - - - Mate efflux family protein
HMMFCFNL_02393 1.41e-207 yisR - - K - - - Transcriptional regulator
HMMFCFNL_02394 1.76e-233 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HMMFCFNL_02395 1.36e-244 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
HMMFCFNL_02396 1.72e-120 yisT - - S - - - DinB family
HMMFCFNL_02397 6.06e-137 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
HMMFCFNL_02398 2.18e-175 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HMMFCFNL_02399 3.51e-160 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HMMFCFNL_02400 2.15e-96 yisX - - S - - - Pentapeptide repeats (9 copies)
HMMFCFNL_02401 5.29e-198 yisY 1.11.1.10 - I ko:K00433 - ko00000,ko01000 hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HMMFCFNL_02402 4.06e-145 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
HMMFCFNL_02403 3.62e-291 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
HMMFCFNL_02404 7.51e-182 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
HMMFCFNL_02405 2.29e-154 - 3.1.3.71 - H ko:K05979 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the ComB family
HMMFCFNL_02406 7.15e-179 yitD 4.4.1.19 - S ko:K08097 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 synthase
HMMFCFNL_02407 6.77e-145 yitE - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
HMMFCFNL_02408 4.32e-283 yitF 5.5.1.27 - M ko:K18983 ko00053,map00053 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
HMMFCFNL_02409 8.28e-291 yitG - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HMMFCFNL_02410 1.29e-196 yitH - - K - - - Acetyltransferase (GNAT) domain
HMMFCFNL_02411 2.16e-93 - - - S - - - Acetyltransferase (GNAT) domain
HMMFCFNL_02412 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HMMFCFNL_02413 1.75e-76 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
HMMFCFNL_02414 2.26e-203 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
HMMFCFNL_02415 4.16e-122 - - - - - - - -
HMMFCFNL_02416 1.66e-217 - - - - - - - -
HMMFCFNL_02417 3.29e-127 - - - S - - - Sporulation delaying protein SdpA
HMMFCFNL_02418 2.08e-77 - - - K - - - Transcriptional regulator PadR-like family
HMMFCFNL_02419 1.23e-119 - - - - - - - -
HMMFCFNL_02420 4.59e-59 yitR - - S - - - Domain of unknown function (DUF3784)
HMMFCFNL_02421 0.0 nprB 3.4.24.28 - E ko:K01400,ko:K08777 ko02024,map02024 ko00000,ko00001,ko01000,ko01002 Peptidase M4
HMMFCFNL_02422 1.24e-199 yitS - - S - - - protein conserved in bacteria
HMMFCFNL_02423 2.29e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
HMMFCFNL_02424 9.69e-94 ipi - - S - - - Intracellular proteinase inhibitor
HMMFCFNL_02425 1.01e-25 - - - S - - - Protein of unknown function (DUF3813)
HMMFCFNL_02426 1.52e-198 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
HMMFCFNL_02427 1.69e-183 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
HMMFCFNL_02428 3.26e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
HMMFCFNL_02429 1.74e-31 - - - S - - - Proteolipid membrane potential modulator
HMMFCFNL_02430 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
HMMFCFNL_02431 3.24e-114 yitZ - - G - - - Major Facilitator Superfamily
HMMFCFNL_02432 3.52e-253 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HMMFCFNL_02433 8.28e-292 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HMMFCFNL_02434 1.27e-175 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
HMMFCFNL_02435 5.65e-277 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
HMMFCFNL_02436 1.91e-261 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
HMMFCFNL_02437 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
HMMFCFNL_02438 4.27e-225 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HMMFCFNL_02439 2.51e-39 yjzC - - S - - - YjzC-like protein
HMMFCFNL_02440 2.17e-23 yjzD - - S - - - Protein of unknown function (DUF2929)
HMMFCFNL_02441 2.42e-182 yjaU - - I - - - carboxylic ester hydrolase activity
HMMFCFNL_02442 5.84e-129 yjaV - - - - - - -
HMMFCFNL_02443 3.7e-234 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
HMMFCFNL_02444 1.07e-35 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
HMMFCFNL_02445 4.61e-32 yjzB - - - - - - -
HMMFCFNL_02446 1.61e-221 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HMMFCFNL_02447 3.06e-302 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HMMFCFNL_02448 8.73e-189 yjaZ - - O - - - Zn-dependent protease
HMMFCFNL_02449 1.76e-233 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HMMFCFNL_02450 2.42e-236 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HMMFCFNL_02451 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
HMMFCFNL_02452 6.73e-216 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HMMFCFNL_02453 1.48e-197 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HMMFCFNL_02454 3.18e-190 yjbA - - S - - - Belongs to the UPF0736 family
HMMFCFNL_02455 6.15e-235 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
HMMFCFNL_02456 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HMMFCFNL_02457 1.03e-212 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HMMFCFNL_02458 7.55e-212 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HMMFCFNL_02459 5.56e-249 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HMMFCFNL_02460 1.27e-219 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HMMFCFNL_02461 6.46e-258 yjbB - - EGP - - - Major Facilitator Superfamily
HMMFCFNL_02462 8.88e-132 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HMMFCFNL_02463 1.01e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HMMFCFNL_02464 7.1e-144 yjbE - - P - - - Integral membrane protein TerC family
HMMFCFNL_02465 4.65e-149 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HMMFCFNL_02466 6.97e-279 coiA - - S ko:K06198 - ko00000 Competence protein
HMMFCFNL_02467 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
HMMFCFNL_02468 2.68e-28 - - - - - - - -
HMMFCFNL_02469 1.32e-218 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
HMMFCFNL_02470 2.03e-92 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
HMMFCFNL_02471 3.42e-127 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HMMFCFNL_02472 7.32e-130 yjbK - - S - - - protein conserved in bacteria
HMMFCFNL_02473 5.35e-81 yjbL - - S - - - Belongs to the UPF0738 family
HMMFCFNL_02474 5.06e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
HMMFCFNL_02475 2.94e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HMMFCFNL_02476 1.49e-202 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
HMMFCFNL_02477 3.3e-180 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
HMMFCFNL_02478 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HMMFCFNL_02479 5.7e-177 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HMMFCFNL_02480 4.49e-136 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
HMMFCFNL_02481 1.09e-275 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
HMMFCFNL_02482 2.18e-41 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 thiamine diphosphate biosynthetic process
HMMFCFNL_02483 6.78e-174 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HMMFCFNL_02484 5.08e-237 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HMMFCFNL_02485 4.85e-191 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HMMFCFNL_02486 1.23e-182 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
HMMFCFNL_02487 2.32e-107 yjbX - - S - - - Spore coat protein
HMMFCFNL_02488 4.57e-108 cotZ - - S ko:K06344 - ko00000 Spore coat protein
HMMFCFNL_02489 3.12e-124 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
HMMFCFNL_02490 5.55e-65 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
HMMFCFNL_02491 3.45e-26 cotW - - - ko:K06341 - ko00000 -
HMMFCFNL_02492 2.28e-53 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
HMMFCFNL_02493 5.88e-74 yjcA - - S - - - Protein of unknown function (DUF1360)
HMMFCFNL_02496 1.88e-52 spoVIF - - S - - - Stage VI sporulation protein F
HMMFCFNL_02497 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
HMMFCFNL_02498 6.31e-51 - - - - - - - -
HMMFCFNL_02499 7.75e-94 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HMMFCFNL_02500 1.2e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
HMMFCFNL_02501 1.63e-178 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
HMMFCFNL_02502 1.89e-271 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HMMFCFNL_02503 7.47e-280 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HMMFCFNL_02504 2.39e-126 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
HMMFCFNL_02505 2.88e-271 yjcL - - S - - - Protein of unknown function (DUF819)
HMMFCFNL_02507 2.93e-19 - - - - - - - -
HMMFCFNL_02508 3.39e-53 - - - - - - - -
HMMFCFNL_02509 3.27e-41 - - - - - - - -
HMMFCFNL_02512 3.61e-79 - - - - - - - -
HMMFCFNL_02514 6.13e-21 - - - S - - - peptidoglycan catabolic process
HMMFCFNL_02515 2.09e-45 - - - S - - - peptidoglycan catabolic process
HMMFCFNL_02517 2.54e-39 - - - S - - - Domain of unknown function (DUF4917)
HMMFCFNL_02518 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HMMFCFNL_02519 5.1e-108 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
HMMFCFNL_02523 1.55e-33 - - - - - - - -
HMMFCFNL_02525 2.57e-61 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
HMMFCFNL_02526 1.62e-179 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
HMMFCFNL_02527 0.000759 - - - - - - - -
HMMFCFNL_02528 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
HMMFCFNL_02529 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HMMFCFNL_02530 1.4e-237 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
HMMFCFNL_02531 9.24e-76 yjdF3 - - S - - - Protein of unknown function (DUF2992)
HMMFCFNL_02532 8.85e-118 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HMMFCFNL_02534 8.3e-105 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HMMFCFNL_02535 1.45e-38 - - - S - - - Domain of unknown function (DUF4177)
HMMFCFNL_02536 2.31e-69 yjdJ - - S - - - Domain of unknown function (DUF4306)
HMMFCFNL_02537 1.03e-221 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HMMFCFNL_02539 0.0 yjeA 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
HMMFCFNL_02540 2.22e-108 - - - S - - - Protein of unknown function (DUF2690)
HMMFCFNL_02541 1.13e-29 yjfB - - S - - - Putative motility protein
HMMFCFNL_02542 6.01e-57 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
HMMFCFNL_02543 2.22e-136 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
HMMFCFNL_02544 1.38e-59 yjgA - - T - - - Protein of unknown function (DUF2809)
HMMFCFNL_02545 4.96e-133 yjgB - - S - - - Domain of unknown function (DUF4309)
HMMFCFNL_02546 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
HMMFCFNL_02547 1.6e-122 yjgD - - S - - - Protein of unknown function (DUF1641)
HMMFCFNL_02549 4.15e-144 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
HMMFCFNL_02551 6.72e-286 yjiB 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
HMMFCFNL_02552 2.92e-278 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HMMFCFNL_02553 1.11e-41 - - - - - - - -
HMMFCFNL_02554 1.01e-187 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
HMMFCFNL_02555 1.82e-155 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
HMMFCFNL_02556 5.64e-175 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HMMFCFNL_02557 6.3e-225 yjlA - - EG - - - Putative multidrug resistance efflux transporter
HMMFCFNL_02558 2.02e-117 yjlB - - S - - - Cupin domain
HMMFCFNL_02559 1.39e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
HMMFCFNL_02560 2.15e-280 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HMMFCFNL_02561 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
HMMFCFNL_02562 1.19e-311 - - - G ko:K03292 - ko00000 symporter YjmB
HMMFCFNL_02563 4.91e-240 allD 1.1.1.350 - C ko:K00073 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000 Belongs to the LDH2 MDH2 oxidoreductase family
HMMFCFNL_02564 5.12e-243 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
HMMFCFNL_02565 1.86e-271 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
HMMFCFNL_02566 2.23e-195 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HMMFCFNL_02567 5.58e-289 exuT - - G ko:K03535,ko:K08191 - ko00000,ko02000 Sugar (and other) transporter
HMMFCFNL_02568 9.87e-238 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
HMMFCFNL_02569 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
HMMFCFNL_02570 0.0 uxaA 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
HMMFCFNL_02571 4.56e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
HMMFCFNL_02572 4.68e-104 yjoA - - S - - - DinB family
HMMFCFNL_02573 7.02e-86 VCP - - O - - - AAA domain (dynein-related subfamily)
HMMFCFNL_02574 3.54e-188 VCP - - O - - - AAA domain (dynein-related subfamily)
HMMFCFNL_02575 8.59e-272 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
HMMFCFNL_02577 1.79e-55 - - - S - - - YCII-related domain
HMMFCFNL_02578 3.09e-217 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
HMMFCFNL_02579 2.24e-79 yjqA - - S - - - Bacterial PH domain
HMMFCFNL_02580 5.3e-137 yjqB - - S - - - Pfam:DUF867
HMMFCFNL_02581 4.54e-204 yjqC - - P ko:K07217 - ko00000 Catalase
HMMFCFNL_02582 1.53e-144 xkdA - - E - - - IrrE N-terminal-like domain
HMMFCFNL_02583 2.01e-74 xre - - K - - - Helix-turn-helix XRE-family like proteins
HMMFCFNL_02585 1.78e-201 xkdB - - K - - - sequence-specific DNA binding
HMMFCFNL_02586 7.48e-153 xkdC - - L - - - Bacterial dnaA protein
HMMFCFNL_02590 2.72e-108 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HMMFCFNL_02591 4.58e-177 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
HMMFCFNL_02592 0.0 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
HMMFCFNL_02593 0.0 yqbA - - S - - - portal protein
HMMFCFNL_02594 5.71e-176 xkdF3 - - L - - - Putative phage serine protease XkdF
HMMFCFNL_02595 3.91e-217 xkdG - - S - - - Phage capsid family
HMMFCFNL_02596 1.63e-82 yqbG - - S - - - Protein of unknown function (DUF3199)
HMMFCFNL_02597 1.75e-84 yqbH - - S - - - Domain of unknown function (DUF3599)
HMMFCFNL_02598 1.67e-114 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
HMMFCFNL_02599 2.87e-101 xkdJ - - - - - - -
HMMFCFNL_02600 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
HMMFCFNL_02601 6.01e-99 xkdM - - S - - - Phage tail tube protein
HMMFCFNL_02602 3.34e-101 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
HMMFCFNL_02603 0.0 xkdO - - L - - - Transglycosylase SLT domain
HMMFCFNL_02604 6.91e-156 xkdP - - S - - - Lysin motif
HMMFCFNL_02605 2.31e-232 xkdQ - - G - - - NLP P60 protein
HMMFCFNL_02606 1.02e-51 xkdR - - S - - - Protein of unknown function (DUF2577)
HMMFCFNL_02607 1.1e-89 xkdS - - S - - - Protein of unknown function (DUF2634)
HMMFCFNL_02608 1.47e-242 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HMMFCFNL_02609 6.51e-134 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
HMMFCFNL_02610 7.36e-55 - - - - - - - -
HMMFCFNL_02611 0.0 - - - - - - - -
HMMFCFNL_02612 8.66e-58 - - - S - - - XkdW protein
HMMFCFNL_02613 6.35e-31 xkdX - - - - - - -
HMMFCFNL_02614 8.05e-194 xepA - - - - - - -
HMMFCFNL_02615 2.21e-51 xhlA - - S - - - Haemolysin XhlA
HMMFCFNL_02616 1.15e-52 xhlB - - S - - - SPP1 phage holin
HMMFCFNL_02617 3.73e-208 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
HMMFCFNL_02619 1.78e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
HMMFCFNL_02620 1.19e-175 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
HMMFCFNL_02621 1.54e-225 pit - - P ko:K03306 - ko00000 phosphate transporter
HMMFCFNL_02622 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
HMMFCFNL_02623 6.06e-308 steT - - E ko:K03294 - ko00000 amino acid
HMMFCFNL_02624 8.07e-233 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
HMMFCFNL_02625 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HMMFCFNL_02626 1.82e-228 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
HMMFCFNL_02628 2.41e-284 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HMMFCFNL_02629 4.95e-180 proG 1.5.1.2 - E ko:K00286,ko:K02239 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko02044 Pyrroline-5-carboxylate reductase
HMMFCFNL_02630 1.4e-196 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
HMMFCFNL_02631 9.7e-204 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HMMFCFNL_02632 3.02e-224 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HMMFCFNL_02633 1.06e-233 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HMMFCFNL_02634 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HMMFCFNL_02636 6.49e-223 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
HMMFCFNL_02637 2.3e-255 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
HMMFCFNL_02638 2.33e-206 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HMMFCFNL_02639 8.44e-237 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HMMFCFNL_02640 8.08e-261 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
HMMFCFNL_02641 1.78e-205 ykgA - - E - - - Amidinotransferase
HMMFCFNL_02642 1.55e-119 ykhA - - I - - - Acyl-CoA hydrolase
HMMFCFNL_02643 5.35e-289 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HMMFCFNL_02644 1.33e-17 - - - - - - - -
HMMFCFNL_02645 3.95e-167 ykjA - - S - - - Protein of unknown function (DUF421)
HMMFCFNL_02646 1.07e-126 ykkA - - S - - - Protein of unknown function (DUF664)
HMMFCFNL_02647 1.2e-126 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HMMFCFNL_02648 1.27e-72 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
HMMFCFNL_02649 1.36e-66 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
HMMFCFNL_02650 4.77e-217 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HMMFCFNL_02651 4.3e-255 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HMMFCFNL_02652 1.32e-288 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HMMFCFNL_02653 2.39e-93 ohrA - - O - - - Organic hydroperoxide resistance protein
HMMFCFNL_02654 1.42e-97 ohrR - - K - - - COG1846 Transcriptional regulators
HMMFCFNL_02655 3.32e-93 ohrB - - O - - - Organic hydroperoxide resistance protein
HMMFCFNL_02656 3.29e-114 guaD 3.5.4.3 - FJ ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 COG0590 Cytosine adenosine deaminases
HMMFCFNL_02657 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HMMFCFNL_02658 3.66e-226 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HMMFCFNL_02659 3.99e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HMMFCFNL_02660 3.12e-174 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
HMMFCFNL_02661 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HMMFCFNL_02662 1.39e-127 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
HMMFCFNL_02663 9.94e-142 ykoF - - S - - - YKOF-related Family
HMMFCFNL_02664 1.06e-159 ykoG - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HMMFCFNL_02665 7.7e-310 ykoH - - T - - - Histidine kinase
HMMFCFNL_02666 3.35e-146 ykoI - - S - - - Peptidase propeptide and YPEB domain
HMMFCFNL_02667 1.51e-110 ykoJ - - S - - - Peptidase propeptide and YPEB domain
HMMFCFNL_02668 1.45e-08 - - - - - - - -
HMMFCFNL_02670 9.86e-300 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
HMMFCFNL_02671 1.49e-70 tnrA - - K - - - transcriptional
HMMFCFNL_02672 1.63e-25 - - - - - - - -
HMMFCFNL_02673 3.04e-36 ykoL - - - - - - -
HMMFCFNL_02674 9.83e-106 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
HMMFCFNL_02675 1.62e-279 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
HMMFCFNL_02676 2.38e-127 ykoP - - G - - - polysaccharide deacetylase
HMMFCFNL_02677 2.07e-196 ykoQ - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
HMMFCFNL_02678 0.0 ykoS - - - - - - -
HMMFCFNL_02679 9.49e-238 ykoT - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
HMMFCFNL_02680 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
HMMFCFNL_02681 5.1e-204 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HMMFCFNL_02682 0.0 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
HMMFCFNL_02683 1.71e-143 ykoX - - S - - - membrane-associated protein
HMMFCFNL_02684 3.39e-179 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HMMFCFNL_02685 1.8e-167 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HMMFCFNL_02686 9.93e-200 rsgI - - S - - - Anti-sigma factor N-terminus
HMMFCFNL_02687 1.4e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
HMMFCFNL_02688 1.55e-159 ykrK - - S - - - Domain of unknown function (DUF1836)
HMMFCFNL_02689 3.97e-199 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
HMMFCFNL_02690 2.58e-310 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
HMMFCFNL_02692 1.77e-28 ykzE - - - - - - -
HMMFCFNL_02693 9.58e-244 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
HMMFCFNL_02694 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HMMFCFNL_02695 2.76e-115 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HMMFCFNL_02697 1.33e-252 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HMMFCFNL_02698 2.37e-291 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HMMFCFNL_02699 4.7e-192 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HMMFCFNL_02700 2.78e-295 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HMMFCFNL_02701 3.39e-295 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
HMMFCFNL_02702 1.02e-174 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
HMMFCFNL_02703 1.84e-146 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
HMMFCFNL_02704 8.7e-123 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HMMFCFNL_02705 8.49e-66 - - - S - - - Protein of unknown function (DUF1232)
HMMFCFNL_02707 5.84e-95 eag - - - - - - -
HMMFCFNL_02708 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
HMMFCFNL_02709 5.17e-99 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
HMMFCFNL_02710 4.91e-170 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
HMMFCFNL_02711 2.01e-178 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
HMMFCFNL_02712 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
HMMFCFNL_02713 7.88e-226 ykvI - - S - - - membrane
HMMFCFNL_02714 6.42e-161 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HMMFCFNL_02715 6.96e-105 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
HMMFCFNL_02716 2.06e-178 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HMMFCFNL_02717 2.36e-125 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HMMFCFNL_02718 2.8e-81 ykvN - - K - - - Transcriptional regulator
HMMFCFNL_02719 7.68e-172 ykvO - - IQ - - - Enoyl-(Acyl carrier protein) reductase
HMMFCFNL_02720 1.47e-45 - - - M - - - Glycosyl transferases group 1
HMMFCFNL_02721 3.38e-234 - - - M - - - Glycosyl transferases group 1
HMMFCFNL_02722 7.56e-48 - 3.5.1.104 - M ko:K22278 - ko00000,ko01000 LysM domain
HMMFCFNL_02723 1.01e-203 - - - G - - - Glycosyl hydrolases family 18
HMMFCFNL_02724 2.67e-62 ykvR - - S - - - Protein of unknown function (DUF3219)
HMMFCFNL_02725 5.43e-35 ykvS - - S - - - protein conserved in bacteria
HMMFCFNL_02726 2.5e-39 - - - - - - - -
HMMFCFNL_02727 5.26e-141 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
HMMFCFNL_02728 6.46e-302 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HMMFCFNL_02729 5.79e-117 stoA - - CO - - - thiol-disulfide
HMMFCFNL_02730 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
HMMFCFNL_02731 3.99e-09 - - - - - - - -
HMMFCFNL_02732 1.93e-264 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
HMMFCFNL_02733 2.21e-228 ykvZ - - K - - - Transcriptional regulator
HMMFCFNL_02735 6.87e-168 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
HMMFCFNL_02736 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HMMFCFNL_02737 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
HMMFCFNL_02738 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HMMFCFNL_02739 1.54e-51 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
HMMFCFNL_02740 2.49e-256 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
HMMFCFNL_02741 1.52e-162 ykwB - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HMMFCFNL_02742 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HMMFCFNL_02743 4.02e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HMMFCFNL_02744 1.68e-17 vgb - - H ko:K18235 - ko00000,ko01000,ko01504 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid
HMMFCFNL_02745 3.62e-170 ykwD - - J - - - protein with SCP PR1 domains
HMMFCFNL_02746 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HMMFCFNL_02747 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HMMFCFNL_02748 2.82e-281 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HMMFCFNL_02749 1.05e-22 - - - - - - - -
HMMFCFNL_02750 4.95e-216 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
HMMFCFNL_02751 2.15e-109 ykyB - - S - - - YkyB-like protein
HMMFCFNL_02752 7.3e-305 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
HMMFCFNL_02753 5.84e-115 ykuD - - S - - - protein conserved in bacteria
HMMFCFNL_02754 3.48e-212 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
HMMFCFNL_02755 3.03e-181 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HMMFCFNL_02756 1.44e-297 ykuI - - T - - - Diguanylate phosphodiesterase
HMMFCFNL_02757 5.16e-50 ykuJ - - S - - - protein conserved in bacteria
HMMFCFNL_02758 3.73e-121 - - - S ko:K09776 - ko00000 Ribonuclease H-like
HMMFCFNL_02759 7.83e-38 ykzF - - S - - - Antirepressor AbbA
HMMFCFNL_02760 5.15e-100 ykuL - - S - - - CBS domain
HMMFCFNL_02761 6.52e-216 ccpC - - K - - - Transcriptional regulator
HMMFCFNL_02762 1.18e-108 - - - C ko:K03839 - ko00000 Flavodoxin domain
HMMFCFNL_02763 3.51e-222 ykuO - - - - - - -
HMMFCFNL_02764 2.08e-101 fld - - C ko:K03839 - ko00000 Flavodoxin
HMMFCFNL_02765 1.31e-125 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HMMFCFNL_02766 1.27e-272 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HMMFCFNL_02767 7.23e-51 ykuS - - S - - - Belongs to the UPF0180 family
HMMFCFNL_02768 4.1e-181 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
HMMFCFNL_02769 9.78e-130 ykuU - - O - - - Alkyl hydroperoxide reductase
HMMFCFNL_02770 6.01e-104 ykuV - - CO - - - thiol-disulfide
HMMFCFNL_02771 1.78e-120 rok - - K - - - Repressor of ComK
HMMFCFNL_02772 2.83e-199 yknT - - - ko:K06437 - ko00000 -
HMMFCFNL_02773 3.75e-141 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HMMFCFNL_02774 2.54e-243 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HMMFCFNL_02775 4.11e-311 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
HMMFCFNL_02776 3.44e-122 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
HMMFCFNL_02777 6.61e-110 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
HMMFCFNL_02778 2.82e-44 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HMMFCFNL_02779 0.0 yknU - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HMMFCFNL_02780 0.0 yknV - - V ko:K02021,ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HMMFCFNL_02781 8.85e-149 yknW - - S - - - Yip1 domain
HMMFCFNL_02782 1.06e-229 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HMMFCFNL_02783 6.1e-160 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HMMFCFNL_02784 2.24e-264 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
HMMFCFNL_02785 7.41e-176 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
HMMFCFNL_02786 4.07e-215 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
HMMFCFNL_02787 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HMMFCFNL_02788 1.72e-134 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HMMFCFNL_02789 5.43e-52 ykoA - - - - - - -
HMMFCFNL_02790 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HMMFCFNL_02791 6.74e-214 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HMMFCFNL_02792 2.07e-303 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
HMMFCFNL_02793 1.09e-18 - - - S - - - Uncharacterized protein YkpC
HMMFCFNL_02794 6.17e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
HMMFCFNL_02795 2.63e-58 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
HMMFCFNL_02796 2.65e-306 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
HMMFCFNL_02797 8.06e-197 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
HMMFCFNL_02798 1.68e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
HMMFCFNL_02799 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HMMFCFNL_02800 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HMMFCFNL_02801 8.98e-42 ykzG - - S - - - Belongs to the UPF0356 family
HMMFCFNL_02802 1.18e-186 ykrA - - S - - - hydrolases of the HAD superfamily
HMMFCFNL_02803 3.96e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HMMFCFNL_02804 1.26e-07 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
HMMFCFNL_02805 1.06e-138 ykyA - - L - - - Putative cell-wall binding lipoprotein
HMMFCFNL_02806 1.06e-258 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HMMFCFNL_02807 3.52e-227 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HMMFCFNL_02808 1.47e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HMMFCFNL_02809 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HMMFCFNL_02810 4.55e-83 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
HMMFCFNL_02811 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
HMMFCFNL_02812 1.34e-56 yktA - - S - - - Belongs to the UPF0223 family
HMMFCFNL_02813 2.15e-151 yktB - - S - - - Belongs to the UPF0637 family
HMMFCFNL_02814 4.48e-35 ykzI - - - - - - -
HMMFCFNL_02815 2.14e-191 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
HMMFCFNL_02816 1.17e-97 ykzC - - S - - - Acetyltransferase (GNAT) family
HMMFCFNL_02817 1.01e-220 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HMMFCFNL_02818 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
HMMFCFNL_02819 0.0 ylaA - - - - - - -
HMMFCFNL_02820 1.44e-56 ylaB - - - - - - -
HMMFCFNL_02821 2.51e-115 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HMMFCFNL_02823 5.7e-56 ylaE - - - - - - -
HMMFCFNL_02824 2.21e-30 - - - S - - - Family of unknown function (DUF5325)
HMMFCFNL_02825 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
HMMFCFNL_02826 4.4e-63 ylaH - - S - - - YlaH-like protein
HMMFCFNL_02827 3.64e-43 ylaI - - S - - - protein conserved in bacteria
HMMFCFNL_02828 9.93e-126 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HMMFCFNL_02829 3.76e-316 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
HMMFCFNL_02830 9.32e-112 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HMMFCFNL_02831 3.49e-219 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
HMMFCFNL_02832 6.94e-59 ylaN - - S - - - Belongs to the UPF0358 family
HMMFCFNL_02833 2.65e-270 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
HMMFCFNL_02834 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HMMFCFNL_02835 2.85e-212 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HMMFCFNL_02836 1.7e-208 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HMMFCFNL_02837 2.38e-252 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HMMFCFNL_02838 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HMMFCFNL_02839 1.84e-145 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HMMFCFNL_02840 6.09e-70 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HMMFCFNL_02841 2.01e-212 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
HMMFCFNL_02842 1.61e-81 ylbA - - S - - - YugN-like family
HMMFCFNL_02843 1.08e-97 ylbB - - T - - - COG0517 FOG CBS domain
HMMFCFNL_02844 5.13e-255 ylbC - - S - - - protein with SCP PR1 domains
HMMFCFNL_02845 3.24e-89 ylbD - - S - - - Putative coat protein
HMMFCFNL_02846 1.73e-48 ylbE - - S - - - YlbE-like protein
HMMFCFNL_02847 2.34e-97 ylbF - - S - - - Belongs to the UPF0342 family
HMMFCFNL_02848 4.36e-52 ylbG - - S - - - UPF0298 protein
HMMFCFNL_02849 2.47e-125 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
HMMFCFNL_02850 1.55e-110 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HMMFCFNL_02851 9.11e-281 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
HMMFCFNL_02852 2.56e-176 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
HMMFCFNL_02853 7.81e-239 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
HMMFCFNL_02854 2.7e-297 ylbM - - S - - - Belongs to the UPF0348 family
HMMFCFNL_02856 6.94e-117 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
HMMFCFNL_02857 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
HMMFCFNL_02858 4.72e-107 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HMMFCFNL_02859 1.33e-115 ylbP - - K - - - n-acetyltransferase
HMMFCFNL_02860 1.12e-214 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HMMFCFNL_02861 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HMMFCFNL_02862 9.82e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
HMMFCFNL_02863 1.66e-218 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HMMFCFNL_02864 3.42e-68 ftsL - - D - - - Essential cell division protein
HMMFCFNL_02865 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HMMFCFNL_02866 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
HMMFCFNL_02867 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HMMFCFNL_02868 3.9e-219 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HMMFCFNL_02869 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HMMFCFNL_02870 6.64e-237 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
HMMFCFNL_02871 1.82e-255 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HMMFCFNL_02872 3.74e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
HMMFCFNL_02873 3.37e-178 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HMMFCFNL_02874 2.23e-142 ylxW - - S - - - protein conserved in bacteria
HMMFCFNL_02875 1.5e-132 ylxX - - S - - - protein conserved in bacteria
HMMFCFNL_02876 5.37e-76 sbp - - S - - - small basic protein
HMMFCFNL_02877 4.88e-299 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HMMFCFNL_02878 1.84e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HMMFCFNL_02879 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
HMMFCFNL_02880 7.14e-219 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HMMFCFNL_02881 1.48e-160 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HMMFCFNL_02882 7.99e-180 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HMMFCFNL_02883 1.29e-187 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HMMFCFNL_02884 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
HMMFCFNL_02885 3.58e-51 ylmC - - S - - - sporulation protein
HMMFCFNL_02886 9.17e-204 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
HMMFCFNL_02887 1.28e-161 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HMMFCFNL_02888 1.28e-86 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HMMFCFNL_02889 1.22e-53 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
HMMFCFNL_02890 1.49e-178 ylmH - - S - - - conserved protein, contains S4-like domain
HMMFCFNL_02891 6.44e-100 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
HMMFCFNL_02892 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HMMFCFNL_02893 1.58e-83 ylyA - - T - - - COG1734 DnaK suppressor protein
HMMFCFNL_02894 2.71e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HMMFCFNL_02895 3.52e-225 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HMMFCFNL_02896 4.45e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HMMFCFNL_02897 9.12e-295 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
HMMFCFNL_02898 1.72e-212 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
HMMFCFNL_02899 0.0 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HMMFCFNL_02900 1.31e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
HMMFCFNL_02901 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
HMMFCFNL_02902 4.31e-182 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HMMFCFNL_02903 2.11e-221 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HMMFCFNL_02904 1.88e-163 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HMMFCFNL_02905 8.96e-149 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HMMFCFNL_02907 5.95e-182 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
HMMFCFNL_02908 4.05e-227 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
HMMFCFNL_02909 8.77e-284 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
HMMFCFNL_02910 1.59e-141 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
HMMFCFNL_02911 5.9e-185 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
HMMFCFNL_02912 5.9e-187 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
HMMFCFNL_02913 2.28e-108 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
HMMFCFNL_02914 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
HMMFCFNL_02915 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
HMMFCFNL_02916 8.41e-202 yloC - - S - - - stress-induced protein
HMMFCFNL_02917 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
HMMFCFNL_02918 5.73e-143 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
HMMFCFNL_02919 6.21e-39 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HMMFCFNL_02920 5.13e-286 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HMMFCFNL_02921 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HMMFCFNL_02922 4.8e-109 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HMMFCFNL_02923 7.08e-223 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HMMFCFNL_02924 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HMMFCFNL_02925 8.79e-263 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HMMFCFNL_02926 2.05e-179 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
HMMFCFNL_02927 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
HMMFCFNL_02928 1.12e-214 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HMMFCFNL_02929 9.44e-153 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
HMMFCFNL_02930 1.35e-155 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
HMMFCFNL_02931 7.06e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
HMMFCFNL_02932 3.65e-78 yloU - - S - - - protein conserved in bacteria
HMMFCFNL_02933 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
HMMFCFNL_02934 1.45e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
HMMFCFNL_02935 3.4e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
HMMFCFNL_02936 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HMMFCFNL_02937 6.22e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HMMFCFNL_02938 8.33e-230 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HMMFCFNL_02939 1.86e-218 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
HMMFCFNL_02940 3.5e-167 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
HMMFCFNL_02941 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
HMMFCFNL_02942 2.12e-174 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HMMFCFNL_02943 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
HMMFCFNL_02944 6.83e-227 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HMMFCFNL_02945 1.67e-114 - - - - - - - -
HMMFCFNL_02946 5.64e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HMMFCFNL_02947 3.95e-308 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HMMFCFNL_02948 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
HMMFCFNL_02949 1.2e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
HMMFCFNL_02950 9.77e-80 ylqD - - S - - - YlqD protein
HMMFCFNL_02951 1.84e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HMMFCFNL_02952 2.41e-177 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
HMMFCFNL_02953 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HMMFCFNL_02954 5.7e-200 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HMMFCFNL_02955 2.04e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HMMFCFNL_02956 0.0 ylqG - - - - - - -
HMMFCFNL_02957 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
HMMFCFNL_02958 6.77e-269 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HMMFCFNL_02959 3.09e-213 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HMMFCFNL_02960 3.62e-215 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
HMMFCFNL_02961 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HMMFCFNL_02962 2.22e-313 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HMMFCFNL_02963 1.13e-217 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
HMMFCFNL_02964 3.01e-120 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HMMFCFNL_02965 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HMMFCFNL_02966 1.95e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HMMFCFNL_02967 1.62e-83 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HMMFCFNL_02968 8.81e-98 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
HMMFCFNL_02969 5.5e-53 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
HMMFCFNL_02970 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
HMMFCFNL_02971 6.08e-230 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HMMFCFNL_02972 1.92e-144 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
HMMFCFNL_02973 3.5e-307 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HMMFCFNL_02974 1.79e-91 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
HMMFCFNL_02975 7.29e-72 ylxF - - S - - - MgtE intracellular N domain
HMMFCFNL_02976 3.04e-303 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
HMMFCFNL_02977 2.81e-96 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
HMMFCFNL_02978 1.66e-174 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
HMMFCFNL_02979 5.59e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
HMMFCFNL_02980 6.61e-231 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HMMFCFNL_02981 1.38e-253 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HMMFCFNL_02982 1.22e-76 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
HMMFCFNL_02983 2.81e-130 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
HMMFCFNL_02984 1.21e-141 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
HMMFCFNL_02985 5.23e-50 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
HMMFCFNL_02986 1.47e-170 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
HMMFCFNL_02987 3.89e-244 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HMMFCFNL_02988 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HMMFCFNL_02989 5.65e-256 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
HMMFCFNL_02990 3.14e-200 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
HMMFCFNL_02991 2.58e-252 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HMMFCFNL_02992 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
HMMFCFNL_02993 1.56e-103 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
HMMFCFNL_02994 5.06e-144 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HMMFCFNL_02995 6.74e-112 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HMMFCFNL_02996 1.33e-175 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HMMFCFNL_02997 4.66e-99 ylxL - - - - - - -
HMMFCFNL_02998 1.49e-168 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
HMMFCFNL_02999 9.82e-202 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HMMFCFNL_03000 5.82e-163 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
HMMFCFNL_03001 9.6e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HMMFCFNL_03002 3.84e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HMMFCFNL_03003 3.33e-178 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
HMMFCFNL_03004 1.39e-276 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HMMFCFNL_03005 6.84e-294 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
HMMFCFNL_03006 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HMMFCFNL_03007 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HMMFCFNL_03008 1.34e-104 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
HMMFCFNL_03009 5.49e-261 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
HMMFCFNL_03010 2.01e-57 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
HMMFCFNL_03011 6.16e-63 ylxQ - - J - - - ribosomal protein
HMMFCFNL_03012 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HMMFCFNL_03013 1.11e-59 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
HMMFCFNL_03014 3.29e-75 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HMMFCFNL_03015 3.49e-219 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HMMFCFNL_03016 9.42e-232 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
HMMFCFNL_03017 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HMMFCFNL_03018 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HMMFCFNL_03019 2.15e-234 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
HMMFCFNL_03020 1.62e-295 mlpA - - S - - - Belongs to the peptidase M16 family
HMMFCFNL_03021 1.53e-56 ymxH - - S - - - YlmC YmxH family
HMMFCFNL_03022 5.3e-208 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
HMMFCFNL_03023 8.17e-141 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HMMFCFNL_03024 1.66e-247 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HMMFCFNL_03025 2e-282 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HMMFCFNL_03026 9.08e-201 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HMMFCFNL_03027 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HMMFCFNL_03028 5.01e-171 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
HMMFCFNL_03029 4.94e-44 - - - S - - - YlzJ-like protein
HMMFCFNL_03030 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
HMMFCFNL_03031 3.02e-170 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
HMMFCFNL_03032 4.19e-265 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HMMFCFNL_03033 1.1e-297 albE - - S - - - Peptidase M16
HMMFCFNL_03034 4.79e-309 ymfH - - S - - - zinc protease
HMMFCFNL_03035 3.01e-166 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
HMMFCFNL_03036 5.13e-55 ymfJ - - S - - - Protein of unknown function (DUF3243)
HMMFCFNL_03037 3.91e-183 ymfK - - S - - - Protein of unknown function (DUF3388)
HMMFCFNL_03038 8.75e-177 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
HMMFCFNL_03039 3.34e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HMMFCFNL_03040 1.06e-299 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
HMMFCFNL_03041 2.72e-238 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HMMFCFNL_03042 3.84e-278 pbpX - - V - - - Beta-lactamase
HMMFCFNL_03043 4.25e-306 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
HMMFCFNL_03044 6.18e-195 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
HMMFCFNL_03045 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
HMMFCFNL_03046 8.31e-253 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
HMMFCFNL_03047 8.02e-276 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HMMFCFNL_03048 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HMMFCFNL_03049 1.27e-89 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
HMMFCFNL_03050 1.74e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
HMMFCFNL_03051 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HMMFCFNL_03052 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HMMFCFNL_03053 1.91e-91 - - - S - - - Regulatory protein YrvL
HMMFCFNL_03055 1.61e-126 ymcC - - S - - - Membrane
HMMFCFNL_03056 4.01e-139 pksA - - K - - - Transcriptional regulator
HMMFCFNL_03057 9.47e-166 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
HMMFCFNL_03058 1.25e-206 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
HMMFCFNL_03060 2.14e-232 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
HMMFCFNL_03061 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
HMMFCFNL_03062 5.46e-51 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
HMMFCFNL_03063 5.31e-304 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HMMFCFNL_03064 4.61e-312 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
HMMFCFNL_03065 2.78e-181 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
HMMFCFNL_03066 1.1e-176 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
HMMFCFNL_03067 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
HMMFCFNL_03068 0.0 - - - Q ko:K13612 - ko00000,ko01004,ko01008 Polyketide synthase of type I
HMMFCFNL_03069 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
HMMFCFNL_03070 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
HMMFCFNL_03071 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
HMMFCFNL_03072 3.39e-295 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
HMMFCFNL_03073 8.03e-81 ymzB - - - - - - -
HMMFCFNL_03074 8.93e-206 - - - S - - - Metallo-beta-lactamase superfamily
HMMFCFNL_03075 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
HMMFCFNL_03077 1.61e-162 ymaC - - S - - - Replication protein
HMMFCFNL_03078 5.98e-105 ymaD - - O - - - redox protein, regulator of disulfide bond formation
HMMFCFNL_03079 1.57e-73 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 COG2076 Membrane transporters of cations and cationic drugs
HMMFCFNL_03080 2.02e-66 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
HMMFCFNL_03082 5.41e-76 ymaF - - S - - - YmaF family
HMMFCFNL_03083 1.38e-223 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HMMFCFNL_03084 1.28e-45 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HMMFCFNL_03085 1.63e-31 - - - - - - - -
HMMFCFNL_03086 1.2e-30 ymzA - - - - - - -
HMMFCFNL_03087 5.01e-66 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
HMMFCFNL_03088 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HMMFCFNL_03089 1.65e-243 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HMMFCFNL_03090 3.05e-139 - - - - - - - -
HMMFCFNL_03091 2.72e-148 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
HMMFCFNL_03092 2.29e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
HMMFCFNL_03093 1.28e-293 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HMMFCFNL_03094 3.37e-310 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HMMFCFNL_03095 4.05e-89 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
HMMFCFNL_03096 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
HMMFCFNL_03097 4.94e-13 - - - - - - - -
HMMFCFNL_03102 4.02e-201 ydhU - - P ko:K07217 - ko00000 Catalase
HMMFCFNL_03103 1.86e-268 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
HMMFCFNL_03104 5.09e-240 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
HMMFCFNL_03105 3.34e-212 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
HMMFCFNL_03106 7.75e-171 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
HMMFCFNL_03107 0.0 ydhP 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HMMFCFNL_03108 2.27e-305 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMMFCFNL_03109 3.39e-67 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HMMFCFNL_03110 1.88e-63 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HMMFCFNL_03111 2.56e-254 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
HMMFCFNL_03112 1.5e-125 ydhK - - M - - - Protein of unknown function (DUF1541)
HMMFCFNL_03113 3.67e-229 ydhJ - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HMMFCFNL_03114 6.55e-109 - - - K - - - Acetyltransferase (GNAT) domain
HMMFCFNL_03116 2.26e-87 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
HMMFCFNL_03117 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
HMMFCFNL_03118 3.01e-163 - - - - - - - -
HMMFCFNL_03119 9.61e-290 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HMMFCFNL_03120 8.26e-290 ydhD - - M - - - Glycosyl hydrolase
HMMFCFNL_03121 1.49e-148 ydhC - - K - - - FCD
HMMFCFNL_03122 8.4e-154 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
HMMFCFNL_03123 4.02e-265 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
HMMFCFNL_03124 3.29e-90 - - - K - - - Winged helix DNA-binding domain
HMMFCFNL_03125 6.42e-147 ydgI - - C - - - nitroreductase
HMMFCFNL_03126 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
HMMFCFNL_03127 8.12e-104 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HMMFCFNL_03128 1.4e-116 - - - S - - - DinB family
HMMFCFNL_03129 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
HMMFCFNL_03130 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
HMMFCFNL_03131 1.1e-108 yycN - - K - - - Acetyltransferase
HMMFCFNL_03132 7e-71 - - - S - - - DoxX-like family
HMMFCFNL_03133 4.92e-127 ydgC - - K - - - Bacterial regulatory proteins, tetR family
HMMFCFNL_03134 8.97e-47 ydgB - - S - - - Spore germination protein gerPA/gerPF
HMMFCFNL_03135 1.53e-47 ydgA - - S - - - Spore germination protein gerPA/gerPF
HMMFCFNL_03136 1.81e-89 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HMMFCFNL_03137 1.6e-138 ydfS - - S - - - Protein of unknown function (DUF421)
HMMFCFNL_03138 8.71e-104 ydfR - - S - - - Protein of unknown function (DUF421)
HMMFCFNL_03140 7.9e-41 - - - - - - - -
HMMFCFNL_03141 2.4e-21 ydgA - - S - - - Spore germination protein gerPA/gerPF
HMMFCFNL_03142 3.11e-73 ydfQ - - CO - - - Thioredoxin
HMMFCFNL_03143 8.02e-84 ydfP - - S ko:K15977 - ko00000 DoxX
HMMFCFNL_03144 1.11e-237 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
HMMFCFNL_03145 1.29e-140 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
HMMFCFNL_03146 6.08e-198 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HMMFCFNL_03147 2.91e-187 - - - K - - - Bacterial transcription activator, effector binding domain
HMMFCFNL_03148 1.31e-149 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
HMMFCFNL_03149 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
HMMFCFNL_03150 2.3e-142 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HMMFCFNL_03151 1.31e-249 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HMMFCFNL_03153 3.92e-104 - - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HMMFCFNL_03154 1.5e-158 ydfF - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HMMFCFNL_03155 4.71e-148 ydfE - - S - - - Flavin reductase like domain
HMMFCFNL_03156 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HMMFCFNL_03157 7.51e-185 - - - EG - - - EamA-like transporter family
HMMFCFNL_03158 3.34e-158 - - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
HMMFCFNL_03159 1.26e-277 - - - T - - - GHKL domain
HMMFCFNL_03160 4.16e-198 - - - - - - - -
HMMFCFNL_03161 1.45e-157 nodB1 - - G - - - deacetylase
HMMFCFNL_03162 1.37e-190 - - - K - - - Transcriptional regulator
HMMFCFNL_03163 1.1e-184 - - - J - - - GNAT acetyltransferase
HMMFCFNL_03164 3.53e-294 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HMMFCFNL_03165 3e-75 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
HMMFCFNL_03166 1.09e-192 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
HMMFCFNL_03167 8.68e-74 - - - K - - - HxlR-like helix-turn-helix
HMMFCFNL_03168 2.81e-134 - - - S ko:K07002 - ko00000 Serine hydrolase
HMMFCFNL_03169 2.49e-95 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
HMMFCFNL_03170 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HMMFCFNL_03171 5.21e-194 ydeK - - EG - - - -transporter
HMMFCFNL_03172 1.28e-143 - - - - - - - -
HMMFCFNL_03173 4.53e-132 ydeI - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
HMMFCFNL_03174 7.89e-71 ydeH - - - - - - -
HMMFCFNL_03175 4.42e-276 ydeG - - EGP - - - Major facilitator superfamily
HMMFCFNL_03176 0.0 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HMMFCFNL_03177 3.34e-212 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
HMMFCFNL_03178 1.17e-222 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HMMFCFNL_03179 1.47e-211 - - - K - - - AraC-like ligand binding domain
HMMFCFNL_03180 3.43e-101 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
HMMFCFNL_03181 4.22e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
HMMFCFNL_03182 2.02e-246 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
HMMFCFNL_03184 1.8e-45 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
HMMFCFNL_03185 4.83e-98 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
HMMFCFNL_03186 0.0 - - - M - - - Domain of unknown function DUF11
HMMFCFNL_03187 1.86e-71 - - - - - - - -
HMMFCFNL_03189 2.92e-91 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
HMMFCFNL_03191 6.29e-93 - - - J - - - Acetyltransferase (GNAT) domain
HMMFCFNL_03199 3.74e-108 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
HMMFCFNL_03200 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
HMMFCFNL_03201 1.79e-100 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HMMFCFNL_03202 1.32e-106 ydcG - - S - - - EVE domain
HMMFCFNL_03205 2.17e-140 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
HMMFCFNL_03206 1.55e-178 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HMMFCFNL_03207 8.3e-110 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HMMFCFNL_03208 3.98e-70 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
HMMFCFNL_03209 1.08e-242 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
HMMFCFNL_03210 2.45e-89 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HMMFCFNL_03211 1.8e-74 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
HMMFCFNL_03212 8.58e-184 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
HMMFCFNL_03213 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
HMMFCFNL_03214 9.49e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HMMFCFNL_03215 1.77e-282 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HMMFCFNL_03216 4.66e-234 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
HMMFCFNL_03217 1.6e-77 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HMMFCFNL_03218 2.53e-139 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
HMMFCFNL_03219 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
HMMFCFNL_03220 2.12e-107 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
HMMFCFNL_03221 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HMMFCFNL_03222 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HMMFCFNL_03223 5.09e-257 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
HMMFCFNL_03224 4.19e-75 ydbP - - CO - - - Thioredoxin
HMMFCFNL_03225 2.72e-202 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HMMFCFNL_03227 1.49e-26 - - - S - - - Fur-regulated basic protein B
HMMFCFNL_03228 8.7e-279 ydbM - - I - - - acyl-CoA dehydrogenase
HMMFCFNL_03229 9.32e-70 ydbL - - - - - - -
HMMFCFNL_03230 2.99e-159 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HMMFCFNL_03231 4.59e-219 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HMMFCFNL_03233 1.32e-230 ydbI - - S - - - AI-2E family transporter
HMMFCFNL_03234 5.16e-289 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HMMFCFNL_03235 3.39e-155 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
HMMFCFNL_03236 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
HMMFCFNL_03237 6.07e-252 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HMMFCFNL_03238 2.24e-197 ydbD - - P ko:K07217 - ko00000 Catalase
HMMFCFNL_03239 4.45e-83 ydbC - - S - - - Domain of unknown function (DUF4937
HMMFCFNL_03240 1.07e-75 ydbB - - G - - - Cupin domain
HMMFCFNL_03241 8.37e-11 gsiB - - S ko:K06884 - ko00000 general stress protein
HMMFCFNL_03242 2.49e-189 ydbA - - P - - - EcsC protein family
HMMFCFNL_03243 9.17e-100 ydaT - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
HMMFCFNL_03244 1.67e-42 ydaS - - S - - - membrane
HMMFCFNL_03245 3.9e-286 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HMMFCFNL_03246 1.45e-51 - - - - - - - -
HMMFCFNL_03247 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
HMMFCFNL_03248 1.9e-66 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
HMMFCFNL_03249 0.0 ydaO - - E - - - amino acid
HMMFCFNL_03250 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
HMMFCFNL_03251 1.12e-303 ydaM - - M - - - Glycosyl transferase family group 2
HMMFCFNL_03252 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
HMMFCFNL_03253 3.66e-192 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
HMMFCFNL_03254 1.41e-263 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
HMMFCFNL_03255 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HMMFCFNL_03256 3.95e-98 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
HMMFCFNL_03257 1.27e-60 ydzA - - EGP - - - Domain of unknown function (DUF3817)
HMMFCFNL_03258 1.87e-178 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HMMFCFNL_03259 5.24e-101 ydaG - - S - - - general stress protein
HMMFCFNL_03260 1.1e-132 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HMMFCFNL_03261 2.75e-125 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
HMMFCFNL_03262 1.07e-206 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HMMFCFNL_03263 7.92e-125 ydaC - - Q - - - Methyltransferase domain
HMMFCFNL_03264 0.0 ydaB - - IQ - - - acyl-CoA ligase
HMMFCFNL_03265 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
HMMFCFNL_03266 2.57e-221 ycsN - - S - - - Oxidoreductase
HMMFCFNL_03267 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
HMMFCFNL_03268 8.97e-65 yczJ - - S - - - biosynthesis
HMMFCFNL_03270 1.57e-149 ycsK - - E - - - anatomical structure formation involved in morphogenesis
HMMFCFNL_03271 6.3e-170 kipR - - K - - - Transcriptional regulator
HMMFCFNL_03272 1.91e-236 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
HMMFCFNL_03273 8.37e-172 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
HMMFCFNL_03274 9.55e-188 ycsI - - S - - - Belongs to the D-glutamate cyclase family
HMMFCFNL_03275 6.53e-272 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
HMMFCFNL_03276 3.01e-178 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
HMMFCFNL_03277 1.9e-177 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
HMMFCFNL_03279 4.45e-86 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
HMMFCFNL_03280 3.32e-141 - - - Q - - - COG0412 Dienelactone hydrolase and related enzymes
HMMFCFNL_03281 1.25e-96 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HMMFCFNL_03282 4.13e-256 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
HMMFCFNL_03283 1.79e-267 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
HMMFCFNL_03284 4.81e-94 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
HMMFCFNL_03285 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
HMMFCFNL_03286 4.67e-75 - - - - - - - -
HMMFCFNL_03287 1.22e-137 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
HMMFCFNL_03288 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
HMMFCFNL_03289 3.05e-138 ycnI - - S - - - protein conserved in bacteria
HMMFCFNL_03290 5.9e-187 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HMMFCFNL_03291 1.67e-190 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
HMMFCFNL_03292 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HMMFCFNL_03293 4.64e-311 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HMMFCFNL_03294 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HMMFCFNL_03295 6.51e-69 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HMMFCFNL_03296 1.68e-60 ycnE - - S - - - Monooxygenase
HMMFCFNL_03297 1.01e-172 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Oxidoreductase
HMMFCFNL_03298 2.91e-198 ycnC - - K - - - Transcriptional regulator
HMMFCFNL_03299 0.0 ycnB - - EGP - - - the major facilitator superfamily
HMMFCFNL_03300 4.69e-212 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
HMMFCFNL_03301 5.63e-176 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HMMFCFNL_03302 3.16e-209 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HMMFCFNL_03303 2.2e-205 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HMMFCFNL_03304 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HMMFCFNL_03307 4.5e-94 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
HMMFCFNL_03308 0.0 yclK - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HMMFCFNL_03309 2.23e-165 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HMMFCFNL_03310 6.2e-277 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
HMMFCFNL_03311 9.73e-155 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
HMMFCFNL_03312 1.36e-246 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
HMMFCFNL_03313 3.21e-285 gerKC - - S ko:K06297 - ko00000 spore germination
HMMFCFNL_03314 0.0 gerKA - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
HMMFCFNL_03316 0.0 yclG - - M - - - Pectate lyase superfamily protein
HMMFCFNL_03317 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
HMMFCFNL_03318 5.5e-202 yclE 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Alpha beta hydrolase
HMMFCFNL_03319 1.45e-107 yclD - - - - - - -
HMMFCFNL_03320 5.71e-52 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
HMMFCFNL_03321 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
HMMFCFNL_03322 1.3e-139 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HMMFCFNL_03323 5.32e-209 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
HMMFCFNL_03324 3.54e-187 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
HMMFCFNL_03325 4.6e-157 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
HMMFCFNL_03326 7.11e-172 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
HMMFCFNL_03327 8.71e-148 yczE - - S ko:K07149 - ko00000 membrane
HMMFCFNL_03328 4.76e-145 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
HMMFCFNL_03329 0.0 ycxD - - K - - - GntR family transcriptional regulator
HMMFCFNL_03330 1.62e-205 ycxC - - EG - - - EamA-like transporter family
HMMFCFNL_03331 1.48e-122 - - - S - - - YcxB-like protein
HMMFCFNL_03332 2.66e-289 - - - EGP - - - Major Facilitator Superfamily
HMMFCFNL_03333 1.91e-178 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
HMMFCFNL_03334 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
HMMFCFNL_03335 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMMFCFNL_03336 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMMFCFNL_03337 6.05e-86 hxlR - - K - - - transcriptional
HMMFCFNL_03338 3.97e-137 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
HMMFCFNL_03339 1.54e-124 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
HMMFCFNL_03340 5.32e-268 tlpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HMMFCFNL_03341 7.94e-100 nucA - - M - - - Deoxyribonuclease NucA/NucB
HMMFCFNL_03342 2.37e-91 nin - - S - - - Competence protein J (ComJ)
HMMFCFNL_03343 0.0 yckE 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HMMFCFNL_03344 1.16e-154 - - - S - - - AAA domain
HMMFCFNL_03345 9e-32 - - - - - - - -
HMMFCFNL_03346 5.24e-58 - - - K - - - MarR family
HMMFCFNL_03347 8.01e-66 yckD - - S - - - Protein of unknown function (DUF2680)
HMMFCFNL_03348 8.73e-83 yckC - - S - - - membrane
HMMFCFNL_03350 2.17e-186 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
HMMFCFNL_03351 3.49e-148 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
HMMFCFNL_03352 3.76e-288 yciC - - S - - - GTPases (G3E family)
HMMFCFNL_03353 4.07e-138 - - - M - - - ErfK YbiS YcfS YnhG
HMMFCFNL_03354 4.09e-220 folE2 3.5.4.16 - S ko:K09007 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Converts GTP to 7,8-dihydroneopterin triphosphate
HMMFCFNL_03355 3.18e-282 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
HMMFCFNL_03356 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
HMMFCFNL_03357 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HMMFCFNL_03358 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HMMFCFNL_03359 1.2e-74 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
HMMFCFNL_03360 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
HMMFCFNL_03361 5.3e-239 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
HMMFCFNL_03362 1.46e-203 ycgS - - I - - - alpha/beta hydrolase fold
HMMFCFNL_03363 9.79e-101 ycgR - - S ko:K07089 - ko00000 permeases
HMMFCFNL_03364 5.14e-69 ycgR - - S ko:K07089 - ko00000 permeases
HMMFCFNL_03365 2.88e-190 ycgQ - - S ko:K08986 - ko00000 membrane
HMMFCFNL_03366 3.92e-288 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
HMMFCFNL_03367 2.64e-316 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HMMFCFNL_03368 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
HMMFCFNL_03369 3.63e-218 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
HMMFCFNL_03370 4.49e-186 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
HMMFCFNL_03371 1.29e-230 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
HMMFCFNL_03372 9.34e-227 ycgK - - K ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 LysR substrate binding domain
HMMFCFNL_03373 1.24e-184 - - - Q - - - ubiE/COQ5 methyltransferase family
HMMFCFNL_03374 1.05e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HMMFCFNL_03375 8.86e-139 tmrB - - S - - - AAA domain
HMMFCFNL_03376 3.69e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HMMFCFNL_03377 7.6e-145 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
HMMFCFNL_03378 0.0 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
HMMFCFNL_03379 1.52e-194 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
HMMFCFNL_03380 3.71e-146 ycgF - - E - - - Lysine exporter protein LysE YggA
HMMFCFNL_03381 2.14e-100 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
HMMFCFNL_03382 0.0 mdr - - EGP - - - the major facilitator superfamily
HMMFCFNL_03383 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
HMMFCFNL_03384 6.9e-232 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HMMFCFNL_03385 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
HMMFCFNL_03386 2.72e-105 ycgB - - - - - - -
HMMFCFNL_03387 0.0 ycgA - - S - - - Membrane
HMMFCFNL_03388 1.89e-274 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
HMMFCFNL_03389 2.01e-210 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
HMMFCFNL_03390 2.1e-186 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
HMMFCFNL_03391 8.99e-293 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
HMMFCFNL_03392 4.82e-61 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HMMFCFNL_03393 2.2e-256 - - - EGP - - - Uncharacterised MFS-type transporter YbfB
HMMFCFNL_03394 2.7e-278 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
HMMFCFNL_03395 4.21e-245 yceH - - P - - - Belongs to the TelA family
HMMFCFNL_03396 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
HMMFCFNL_03397 1.67e-175 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
HMMFCFNL_03398 4.97e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
HMMFCFNL_03399 8.9e-137 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
HMMFCFNL_03400 3.75e-141 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
HMMFCFNL_03401 2.83e-236 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HMMFCFNL_03402 4.63e-173 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HMMFCFNL_03403 2.32e-169 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HMMFCFNL_03404 1.95e-221 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HMMFCFNL_03405 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
HMMFCFNL_03406 5.63e-179 - 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
HMMFCFNL_03407 1.16e-247 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
HMMFCFNL_03408 2.98e-120 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
HMMFCFNL_03409 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HMMFCFNL_03410 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HMMFCFNL_03411 1.35e-241 ycdA - - S - - - Domain of unknown function (DUF5105)
HMMFCFNL_03412 5.59e-221 yccK - - C - - - Aldo keto reductase
HMMFCFNL_03413 6.29e-254 - - - CP ko:K09696 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
HMMFCFNL_03414 2.2e-170 natA 3.6.3.7 - CP ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
HMMFCFNL_03415 6.86e-163 natR - - T ko:K02477,ko:K11641 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
HMMFCFNL_03416 1.36e-200 natK 2.7.13.3 - T ko:K11640 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
HMMFCFNL_03417 8.33e-254 yccF - - K ko:K07039 - ko00000 SEC-C motif
HMMFCFNL_03418 8.72e-78 - - - S - - - RDD family
HMMFCFNL_03419 1.63e-146 - 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
HMMFCFNL_03420 1.69e-257 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HMMFCFNL_03421 6.54e-132 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
HMMFCFNL_03422 1.24e-302 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
HMMFCFNL_03423 2.07e-260 ycbU - - E - - - Selenocysteine lyase
HMMFCFNL_03424 1.4e-153 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HMMFCFNL_03425 3.61e-158 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HMMFCFNL_03426 3.12e-38 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HMMFCFNL_03427 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
HMMFCFNL_03428 3.68e-172 ycbR - - T - - - vWA found in TerF C terminus
HMMFCFNL_03429 5.22e-102 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
HMMFCFNL_03430 2.21e-76 ycbP - - S - - - Protein of unknown function (DUF2512)
HMMFCFNL_03431 2.87e-148 - - - S - - - ABC-2 family transporter protein
HMMFCFNL_03432 3.74e-213 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HMMFCFNL_03433 2.26e-216 ycbM - - T - - - Histidine kinase
HMMFCFNL_03434 1.51e-159 ycbL - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HMMFCFNL_03435 6.77e-177 eamA1 - - EG - - - spore germination
HMMFCFNL_03436 8.73e-33 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
HMMFCFNL_03437 1.43e-221 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
HMMFCFNL_03438 0.0 garD 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
HMMFCFNL_03439 2.3e-161 ycbG - - K ko:K05799 - ko00000,ko03000 FCD
HMMFCFNL_03440 0.0 gudD 4.2.1.40 - M ko:K01706 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
HMMFCFNL_03441 0.0 gudP - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HMMFCFNL_03442 0.0 ycbD - - C ko:K22187 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HMMFCFNL_03443 1.67e-221 ycbC 4.2.1.41 - EM ko:K01707 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 5-dehydro-4-deoxyglucarate dehydratase activity
HMMFCFNL_03444 4.94e-217 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
HMMFCFNL_03445 2.05e-293 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HMMFCFNL_03446 4.35e-238 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
HMMFCFNL_03447 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
HMMFCFNL_03448 1.29e-233 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
HMMFCFNL_03449 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
HMMFCFNL_03450 1.63e-259 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
HMMFCFNL_03452 1.18e-164 - - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
HMMFCFNL_03453 1.43e-172 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HMMFCFNL_03454 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HMMFCFNL_03455 4.25e-273 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HMMFCFNL_03456 1.16e-244 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
HMMFCFNL_03457 7.01e-212 ybfP - - K ko:K13653 - ko00000,ko03000 Transcriptional regulator
HMMFCFNL_03458 0.0 - - - S ko:K06880 - ko00000,ko01000,ko01504 Erythromycin esterase
HMMFCFNL_03459 6.45e-59 ybfN - - - - - - -
HMMFCFNL_03460 2.06e-188 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
HMMFCFNL_03461 7.07e-112 ybfM - - S - - - SNARE associated Golgi protein
HMMFCFNL_03462 2.81e-123 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HMMFCFNL_03463 2.17e-211 - - - S - - - Alpha/beta hydrolase family
HMMFCFNL_03465 4.14e-229 mpr - - M - - - Belongs to the peptidase S1B family
HMMFCFNL_03466 3.78e-270 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HMMFCFNL_03467 1.05e-187 ybfI - - K - - - AraC-like ligand binding domain
HMMFCFNL_03468 8.74e-207 ybfH - - EG - - - EamA-like transporter family
HMMFCFNL_03469 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
HMMFCFNL_03471 1.94e-286 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
HMMFCFNL_03472 1.05e-202 ybfA - - K - - - FR47-like protein
HMMFCFNL_03473 1.02e-46 - - - S - - - Protein of unknown function (DUF2651)
HMMFCFNL_03474 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
HMMFCFNL_03475 5.52e-208 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
HMMFCFNL_03476 0.0 ybeC - - E - - - amino acid
HMMFCFNL_03477 1.11e-54 ybyB - - - - - - -
HMMFCFNL_03478 3.12e-313 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
HMMFCFNL_03479 7.18e-191 ybxI 3.5.2.6 - V ko:K17838 ko01501,map01501 ko00000,ko00001,ko01000 beta-lactamase
HMMFCFNL_03480 8.11e-40 ybxH - - S - - - Family of unknown function (DUF5370)
HMMFCFNL_03481 5.46e-51 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
HMMFCFNL_03482 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
HMMFCFNL_03483 2.11e-272 ybdO - - S - - - Domain of unknown function (DUF4885)
HMMFCFNL_03484 2.2e-175 ybdM 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 Protein tyrosine kinase
HMMFCFNL_03486 1.08e-216 - - - T - - - His Kinase A (phospho-acceptor) domain
HMMFCFNL_03487 9.8e-158 - - - T ko:K02483 - ko00000,ko02022 Transcriptional regulatory protein, C terminal
HMMFCFNL_03488 3.15e-230 - - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HMMFCFNL_03489 6e-76 - - - - - - - -
HMMFCFNL_03490 1.33e-257 ybcL - - EGP ko:K08164 - ko00000,ko02000 COG2814 Arabinose efflux permease
HMMFCFNL_03491 9.45e-67 - - - K - - - Helix-turn-helix domain
HMMFCFNL_03492 3.6e-80 ybcI - - S - - - Uncharacterized conserved protein (DUF2294)
HMMFCFNL_03493 1.6e-63 - - - - - - - -
HMMFCFNL_03494 3.85e-120 ybcF - - P - - - carbonic anhydrase
HMMFCFNL_03495 0.0 ybcC - - S ko:K09822 - ko00000 Belongs to the UPF0753 family
HMMFCFNL_03496 0.0 ndhF 1.6.5.3 - CP ko:K05577 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HMMFCFNL_03497 8.85e-126 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Bacitracin ABC transporter permease
HMMFCFNL_03498 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HMMFCFNL_03499 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HMMFCFNL_03500 3.55e-291 ybbR - - S - - - protein conserved in bacteria
HMMFCFNL_03501 5.43e-189 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HMMFCFNL_03502 1.3e-150 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HMMFCFNL_03503 4.59e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HMMFCFNL_03509 2.43e-100 ybbK - - S - - - Protein of unknown function (DUF523)
HMMFCFNL_03510 2.58e-113 ybbJ - - J - - - acetyltransferase
HMMFCFNL_03511 6.7e-210 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HMMFCFNL_03512 1.28e-192 ybbH - - K - - - transcriptional
HMMFCFNL_03513 6.98e-302 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HMMFCFNL_03514 0.0 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
HMMFCFNL_03515 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
HMMFCFNL_03516 5.73e-303 ybbC - - S - - - protein conserved in bacteria
HMMFCFNL_03517 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
HMMFCFNL_03518 3.6e-216 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
HMMFCFNL_03519 3.36e-225 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HMMFCFNL_03520 1.01e-227 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HMMFCFNL_03521 1.33e-173 ybbA - - S ko:K07017 - ko00000 Putative esterase
HMMFCFNL_03522 2.09e-200 ybaS - - S - - - Na -dependent transporter
HMMFCFNL_03524 0.0 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
HMMFCFNL_03527 1.01e-226 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HMMFCFNL_03528 2.41e-111 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
HMMFCFNL_03529 2.8e-160 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
HMMFCFNL_03530 1.41e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HMMFCFNL_03531 1.34e-240 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HMMFCFNL_03532 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
HMMFCFNL_03533 8.47e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HMMFCFNL_03534 2.14e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HMMFCFNL_03535 5.48e-31 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HMMFCFNL_03536 3.55e-161 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HMMFCFNL_03537 3.2e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
HMMFCFNL_03538 1.74e-166 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
HMMFCFNL_03539 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HMMFCFNL_03540 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HMMFCFNL_03541 1.03e-95 - - - L - - - Phage integrase family
HMMFCFNL_03542 1.54e-40 yddG - - S - - - maturation of SSU-rRNA
HMMFCFNL_03543 4.69e-26 yddG - - S - - - maturation of SSU-rRNA
HMMFCFNL_03544 4.41e-30 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
HMMFCFNL_03545 3.21e-94 - - - E - - - AzlC protein
HMMFCFNL_03546 6.85e-201 gntR9 - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HMMFCFNL_03547 2.48e-18 - - - S - - - B3/4 domain
HMMFCFNL_03548 2.16e-215 megL 4.4.1.11 - E ko:K01761 ko00270,ko00450,map00270,map00450 ko00000,ko00001,ko01000 methionine gamma-lyase
HMMFCFNL_03549 3.29e-158 - - - I - - - Fatty acid desaturase
HMMFCFNL_03550 3.41e-18 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HMMFCFNL_03552 6.03e-190 ydjC - - S - - - Abhydrolase domain containing 18
HMMFCFNL_03553 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
HMMFCFNL_03554 4.32e-258 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
HMMFCFNL_03555 0.0 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
HMMFCFNL_03556 5.78e-219 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
HMMFCFNL_03557 1.08e-147 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
HMMFCFNL_03558 1.73e-226 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HMMFCFNL_03559 3.5e-171 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
HMMFCFNL_03560 1.04e-202 ydjI - - S - - - virion core protein (lumpy skin disease virus)
HMMFCFNL_03561 1.13e-247 - - - S - - - Ion transport 2 domain protein
HMMFCFNL_03562 0.0 iolT - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HMMFCFNL_03563 3.5e-249 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
HMMFCFNL_03564 1.79e-84 ydjM - - M - - - Lytic transglycolase
HMMFCFNL_03565 9.38e-207 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
HMMFCFNL_03567 8.2e-48 ydjO - - S - - - Cold-inducible protein YdjO
HMMFCFNL_03568 2.43e-200 - - - I - - - Alpha/beta hydrolase family
HMMFCFNL_03569 8.92e-225 yeaA - - S - - - Protein of unknown function (DUF4003)
HMMFCFNL_03570 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
HMMFCFNL_03571 0.0 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
HMMFCFNL_03572 1.76e-198 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HMMFCFNL_03573 1.32e-224 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
HMMFCFNL_03574 2.16e-283 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
HMMFCFNL_03575 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
HMMFCFNL_03576 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
HMMFCFNL_03577 2.41e-283 pbuG - - S ko:K06901 - ko00000,ko02000 permease
HMMFCFNL_03578 5.85e-165 yebC - - M - - - Membrane
HMMFCFNL_03580 2.18e-119 yebE - - S - - - UPF0316 protein
HMMFCFNL_03581 3.13e-38 yebG - - S - - - NETI protein
HMMFCFNL_03582 2.28e-108 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HMMFCFNL_03583 6.34e-276 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HMMFCFNL_03584 2.81e-314 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HMMFCFNL_03585 3.39e-167 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
HMMFCFNL_03586 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HMMFCFNL_03587 1.15e-167 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HMMFCFNL_03588 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HMMFCFNL_03589 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HMMFCFNL_03590 9.88e-240 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
HMMFCFNL_03591 3.62e-137 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HMMFCFNL_03592 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
HMMFCFNL_03593 1.63e-297 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
HMMFCFNL_03594 1.06e-95 - - - K - - - helix_turn_helix ASNC type
HMMFCFNL_03595 5.05e-284 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
HMMFCFNL_03596 3.45e-37 - - - S - - - Protein of unknown function (DUF2892)
HMMFCFNL_03597 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
HMMFCFNL_03598 9.58e-244 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
HMMFCFNL_03599 6.27e-67 yerC - - S - - - protein conserved in bacteria
HMMFCFNL_03600 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
HMMFCFNL_03602 1.1e-161 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HMMFCFNL_03603 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
HMMFCFNL_03604 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HMMFCFNL_03605 1.45e-280 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
HMMFCFNL_03606 4.95e-250 yerI - - S - - - homoserine kinase type II (protein kinase fold)
HMMFCFNL_03607 2.29e-160 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
HMMFCFNL_03608 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HMMFCFNL_03609 7.37e-61 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HMMFCFNL_03611 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HMMFCFNL_03612 2.23e-185 yerO - - K - - - Transcriptional regulator
HMMFCFNL_03613 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HMMFCFNL_03614 1.8e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HMMFCFNL_03615 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HMMFCFNL_03616 1.18e-186 - 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 C-5 cytosine-specific DNA methylase
HMMFCFNL_03617 2.66e-173 - - - S - - - type ii restriction enzyme
HMMFCFNL_03618 1.82e-157 - - - S - - - Protein of unknown function DUF262
HMMFCFNL_03619 1.62e-59 - - - - - - - -
HMMFCFNL_03621 7.93e-125 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
HMMFCFNL_03623 2.42e-54 - - - S - - - Immunity protein 22
HMMFCFNL_03624 7.2e-229 - - - S - - - Bacterial EndoU nuclease
HMMFCFNL_03626 8.53e-128 - - - L - - - endonuclease activity
HMMFCFNL_03627 4.98e-209 - 3.4.24.40 - CO ko:K01406 ko01503,map01503 ko00000,ko00001,ko01000,ko01002 amine dehydrogenase activity
HMMFCFNL_03628 4.24e-14 - - - S - - - Pfam:DUF1311
HMMFCFNL_03629 8.24e-270 rapH - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Tetratricopeptide repeat
HMMFCFNL_03631 6.29e-162 yeeN - - K - - - transcriptional regulatory protein
HMMFCFNL_03633 9.93e-130 dhaR3 - - K ko:K16137 - ko00000,ko03000 Transcriptional regulator
HMMFCFNL_03634 1.94e-104 yesE - - S ko:K06893 - ko00000 SnoaL-like domain
HMMFCFNL_03635 4.1e-194 yesF - - GM - - - NAD(P)H-binding
HMMFCFNL_03636 3.8e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
HMMFCFNL_03637 2.31e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
HMMFCFNL_03638 1.04e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
HMMFCFNL_03639 1.19e-130 yesJ - - K - - - Acetyltransferase (GNAT) family
HMMFCFNL_03641 2.56e-132 yesL - - S - - - Protein of unknown function, DUF624
HMMFCFNL_03642 0.0 yesM 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HMMFCFNL_03643 7.38e-253 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
HMMFCFNL_03644 3.39e-313 yesO - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
HMMFCFNL_03645 2.02e-218 yesP - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HMMFCFNL_03646 2.17e-211 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HMMFCFNL_03647 7.67e-252 - 3.2.1.172 GH105 S ko:K15532 - ko00000,ko01000 Glycosyl Hydrolase Family 88
HMMFCFNL_03648 0.0 yesS - - K - - - Transcriptional regulator
HMMFCFNL_03649 4.66e-167 - - - E - - - GDSL-like Lipase/Acylhydrolase
HMMFCFNL_03650 5.08e-163 yesU - - S - - - Domain of unknown function (DUF1961)
HMMFCFNL_03651 6.66e-144 - - - S - - - Protein of unknown function, DUF624
HMMFCFNL_03652 0.0 - 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
HMMFCFNL_03653 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
HMMFCFNL_03654 9.13e-160 - - - E - - - GDSL-like Lipase/Acylhydrolase
HMMFCFNL_03655 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
HMMFCFNL_03656 0.0 yetA - - - - - - -
HMMFCFNL_03657 0.0 lplA - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HMMFCFNL_03658 2.78e-225 lplB - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
HMMFCFNL_03659 7.85e-209 - - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HMMFCFNL_03660 0.0 - 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
HMMFCFNL_03661 3.66e-157 yetF - - S - - - membrane
HMMFCFNL_03662 4.67e-73 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
HMMFCFNL_03663 2.47e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HMMFCFNL_03664 1.75e-44 - - - - - - - -
HMMFCFNL_03665 1.25e-184 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HMMFCFNL_03666 3.81e-28 yezD - - S - - - Uncharacterized small protein (DUF2292)
HMMFCFNL_03667 2.55e-135 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
HMMFCFNL_03668 2.75e-116 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
HMMFCFNL_03669 1.26e-265 yetM - - CH - - - FAD binding domain
HMMFCFNL_03670 1.01e-253 yetN - - S - - - Protein of unknown function (DUF3900)
HMMFCFNL_03671 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
HMMFCFNL_03672 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
HMMFCFNL_03673 4.01e-186 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
HMMFCFNL_03674 1.37e-219 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
HMMFCFNL_03675 9.02e-228 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
HMMFCFNL_03676 2.84e-285 yfnE - - S - - - Glycosyltransferase like family 2
HMMFCFNL_03677 3.88e-242 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
HMMFCFNL_03678 6.21e-268 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HMMFCFNL_03679 1.29e-168 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
HMMFCFNL_03680 3.41e-312 yfnA - - E ko:K03294 - ko00000 amino acid
HMMFCFNL_03681 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HMMFCFNL_03682 5.14e-161 yfmS - - NT - - - chemotaxis protein
HMMFCFNL_03683 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HMMFCFNL_03684 3.61e-96 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
HMMFCFNL_03685 3.54e-90 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
HMMFCFNL_03686 3.59e-265 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
HMMFCFNL_03687 4.96e-64 - - - O - - - Subtilase family
HMMFCFNL_03688 9.1e-23 - - - - - - - -
HMMFCFNL_03690 3.95e-74 - - - - - - - -
HMMFCFNL_03691 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HMMFCFNL_03692 7.25e-264 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
HMMFCFNL_03693 3.75e-98 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
HMMFCFNL_03694 6.69e-239 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
HMMFCFNL_03695 1.4e-192 fhuC 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
HMMFCFNL_03696 2.1e-223 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HMMFCFNL_03697 8.17e-221 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HMMFCFNL_03698 2.76e-219 yfmC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
HMMFCFNL_03699 1.06e-31 - - - S - - - Protein of unknown function (DUF3212)
HMMFCFNL_03700 1.71e-76 yflT - - S - - - Heat induced stress protein YflT
HMMFCFNL_03701 1.73e-307 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
HMMFCFNL_03702 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
HMMFCFNL_03703 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
HMMFCFNL_03704 3.26e-153 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
HMMFCFNL_03705 6.89e-231 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
HMMFCFNL_03706 5.35e-288 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
HMMFCFNL_03707 1.7e-192 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
HMMFCFNL_03708 1.67e-276 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HMMFCFNL_03709 2.97e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
HMMFCFNL_03710 3.42e-157 yflK - - S - - - protein conserved in bacteria
HMMFCFNL_03711 9.08e-25 yflJ - - S - - - Protein of unknown function (DUF2639)
HMMFCFNL_03712 6.9e-27 yflI - - - - - - -
HMMFCFNL_03713 2.1e-65 yflH - - S - - - Protein of unknown function (DUF3243)
HMMFCFNL_03714 1.14e-178 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
HMMFCFNL_03715 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HMMFCFNL_03716 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
HMMFCFNL_03717 4.45e-86 ydhN1 - - S - - - Domain of unknown function (DUF1992)
HMMFCFNL_03718 0.0 yflA - - E ko:K03310 - ko00000 Sodium alanine symporter
HMMFCFNL_03719 3.48e-246 yfkT - - E ko:K06309 - ko00000 Spore germination protein
HMMFCFNL_03721 2.66e-270 yfkR - - S ko:K06297,ko:K06308 - ko00000 spore germination
HMMFCFNL_03722 0.0 yfkQ - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
HMMFCFNL_03723 0.0 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HMMFCFNL_03724 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
HMMFCFNL_03725 1.24e-172 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
HMMFCFNL_03726 6.16e-160 frp - - C - - - nitroreductase
HMMFCFNL_03727 0.0 yfkN 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HMMFCFNL_03728 3.3e-115 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
HMMFCFNL_03729 2.07e-264 ydiN3 - - EGP - - - COG0477 Permeases of the major facilitator superfamily
HMMFCFNL_03730 7.27e-42 yfkK - - S - - - Belongs to the UPF0435 family
HMMFCFNL_03731 9.78e-107 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HMMFCFNL_03732 1.03e-66 yfkI - - S - - - gas vesicle protein
HMMFCFNL_03733 9.64e-184 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
HMMFCFNL_03734 1.64e-12 - - - - - - - -
HMMFCFNL_03735 1.9e-278 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
HMMFCFNL_03736 1.34e-235 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
HMMFCFNL_03737 3.69e-189 yfkD - - S - - - YfkD-like protein
HMMFCFNL_03738 1.27e-190 yfkC - - M - - - Mechanosensitive ion channel
HMMFCFNL_03739 1.76e-283 yfkA - - S - - - YfkB-like domain
HMMFCFNL_03740 3.26e-36 yfjT - - - - - - -
HMMFCFNL_03741 7.24e-198 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
HMMFCFNL_03742 3.63e-189 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HMMFCFNL_03743 3.18e-236 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
HMMFCFNL_03744 5.34e-212 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HMMFCFNL_03745 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HMMFCFNL_03746 3.31e-57 - - - S - - - YfzA-like protein
HMMFCFNL_03747 4.72e-241 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HMMFCFNL_03748 3.74e-108 yfjM - - S - - - Psort location Cytoplasmic, score
HMMFCFNL_03749 1.36e-244 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HMMFCFNL_03750 1.59e-243 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HMMFCFNL_03751 1.82e-259 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HMMFCFNL_03752 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HMMFCFNL_03753 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
HMMFCFNL_03754 8.16e-36 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
HMMFCFNL_03755 7.42e-75 yfjF - - S ko:K09771 - ko00000,ko02000 UPF0060 membrane protein
HMMFCFNL_03756 1.52e-100 - - - S - - - Family of unknown function (DUF5381)
HMMFCFNL_03757 1.49e-131 yfjD - - S - - - Family of unknown function (DUF5381)
HMMFCFNL_03758 2.5e-185 yfjC - - - - - - -
HMMFCFNL_03759 5.56e-270 yfjB - - - - - - -
HMMFCFNL_03760 5.59e-61 yfjA - - S - - - Belongs to the WXG100 family
HMMFCFNL_03761 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HMMFCFNL_03762 5.03e-180 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
HMMFCFNL_03763 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HMMFCFNL_03764 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
HMMFCFNL_03765 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HMMFCFNL_03766 2.86e-84 yfiD3 - - S - - - DoxX
HMMFCFNL_03767 1.16e-205 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
HMMFCFNL_03768 1.69e-239 baeS - - T - - - Histidine kinase
HMMFCFNL_03769 8.27e-144 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
HMMFCFNL_03770 6.45e-212 drrA - - V ko:K01990,ko:K09695 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HMMFCFNL_03771 3.92e-269 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HMMFCFNL_03772 8.45e-263 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
HMMFCFNL_03773 1.89e-128 padR - - K - - - transcriptional
HMMFCFNL_03774 7.87e-128 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
HMMFCFNL_03775 4.43e-251 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HMMFCFNL_03776 1.15e-127 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
HMMFCFNL_03777 0.0 yfiU - - EGP - - - the major facilitator superfamily
HMMFCFNL_03778 2.11e-103 yfiV - - K - - - transcriptional
HMMFCFNL_03779 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HMMFCFNL_03780 3.83e-231 yfiY - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HMMFCFNL_03781 8.91e-225 yfiZ - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HMMFCFNL_03782 7.36e-229 yfhA - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HMMFCFNL_03783 1.21e-211 yfhB - - S - - - PhzF family
HMMFCFNL_03784 1.66e-137 yfhC - - C - - - nitroreductase
HMMFCFNL_03785 8.86e-35 yfhD - - S - - - YfhD-like protein
HMMFCFNL_03787 2.19e-219 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
HMMFCFNL_03788 9.32e-181 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
HMMFCFNL_03789 4.58e-69 yfhH - - S - - - Protein of unknown function (DUF1811)
HMMFCFNL_03791 3.47e-268 yfhI - - EGP - - - -transporter
HMMFCFNL_03792 2.25e-27 sspK - - S ko:K06428 - ko00000 reproduction
HMMFCFNL_03793 8.95e-60 yfhJ - - S - - - WVELL protein
HMMFCFNL_03794 1.91e-114 yfhK - - T - - - Bacterial SH3 domain homologues
HMMFCFNL_03795 1.66e-62 yfhL - - S - - - SdpI/YhfL protein family
HMMFCFNL_03796 1.13e-217 yfhM 3.8.1.5 - S ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Alpha beta hydrolase
HMMFCFNL_03797 3.43e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
HMMFCFNL_03798 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
HMMFCFNL_03799 5.93e-236 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
HMMFCFNL_03800 1.31e-265 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
HMMFCFNL_03801 1.73e-48 yfhS - - - - - - -
HMMFCFNL_03802 3.13e-172 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HMMFCFNL_03803 2.35e-14 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
HMMFCFNL_03804 8.19e-49 ygaB - - S - - - YgaB-like protein
HMMFCFNL_03805 8.1e-136 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
HMMFCFNL_03806 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
HMMFCFNL_03807 1.87e-238 ygaE - - S - - - Membrane
HMMFCFNL_03808 3.26e-312 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
HMMFCFNL_03809 1.69e-112 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
HMMFCFNL_03810 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
HMMFCFNL_03811 3.38e-73 ygzB - - S - - - UPF0295 protein
HMMFCFNL_03812 8.23e-215 ygxA - - S - - - Nucleotidyltransferase-like
HMMFCFNL_03814 4.06e-119 - - - M - - - Glycosyltransferase like family
HMMFCFNL_03815 2.75e-154 - - - H - - - Methionine biosynthesis protein MetW
HMMFCFNL_03816 2.03e-246 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
HMMFCFNL_03817 3.14e-274 - - - H - - - N-terminal domain of galactosyltransferase
HMMFCFNL_03818 1.49e-128 ynaD - - J - - - Acetyltransferase (GNAT) domain
HMMFCFNL_03819 2.62e-92 - - - S - - - CAAX protease self-immunity
HMMFCFNL_03820 3.35e-11 ywlA - - S - - - Uncharacterised protein family (UPF0715)
HMMFCFNL_03821 9.72e-31 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
HMMFCFNL_03822 3.04e-151 - - - S - - - Domain of unknown function (DUF3885)
HMMFCFNL_03823 2.36e-53 ynaF - - - - - - -
HMMFCFNL_03825 1.82e-102 - - - E - - - phosphoribosylanthranilate isomerase activity
HMMFCFNL_03826 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
HMMFCFNL_03827 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
HMMFCFNL_03828 1.23e-275 xylR - - GK - - - ROK family
HMMFCFNL_03829 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
HMMFCFNL_03830 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
HMMFCFNL_03831 6.15e-146 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
HMMFCFNL_03832 0.0 - - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HMMFCFNL_03834 2.06e-279 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HMMFCFNL_03835 5.49e-107 - - - S - - - Protein of unknown function (DUF2691)
HMMFCFNL_03836 3.51e-101 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
HMMFCFNL_03839 1.53e-207 - - - S - - - Thymidylate synthase
HMMFCFNL_03840 8.27e-40 - - - - - - - -
HMMFCFNL_03842 5.34e-166 - - - S - - - Domain of unknown function, YrpD
HMMFCFNL_03845 2.37e-34 tatA - - U ko:K03116,ko:K03117,ko:K03646 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02000,ko02044 protein secretion
HMMFCFNL_03846 8.92e-96 - - - - - - - -
HMMFCFNL_03847 2.47e-101 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
HMMFCFNL_03850 0.0 yndD1 - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
HMMFCFNL_03851 3.94e-250 yndE7 - - U ko:K06311 - ko00000,ko02000 Spore germination
HMMFCFNL_03852 7.59e-287 - - - S ko:K06293,ko:K06312 - ko00000 Spore germination protein
HMMFCFNL_03853 1.25e-196 yndG - - S - - - DoxX-like family
HMMFCFNL_03854 1.65e-147 - - - S - - - Domain of unknown function (DUF4166)
HMMFCFNL_03855 0.0 yndJ - - S - - - YndJ-like protein
HMMFCFNL_03857 6.31e-173 yndL - - S - - - Replication protein
HMMFCFNL_03858 1.32e-96 yndM - - S - - - Protein of unknown function (DUF2512)
HMMFCFNL_03859 1.74e-101 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
HMMFCFNL_03860 7.22e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HMMFCFNL_03861 8.5e-65 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
HMMFCFNL_03862 3.97e-145 yneB - - L - - - resolvase
HMMFCFNL_03863 1.15e-43 ynzC - - S - - - UPF0291 protein
HMMFCFNL_03864 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HMMFCFNL_03865 2.18e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
HMMFCFNL_03866 4.36e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
HMMFCFNL_03867 4.59e-21 ynzD - - S - - - Spo0E like sporulation regulatory protein
HMMFCFNL_03868 4.13e-165 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
HMMFCFNL_03869 2.12e-77 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
HMMFCFNL_03870 3.57e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
HMMFCFNL_03871 3.97e-97 yneK - - S - - - Protein of unknown function (DUF2621)
HMMFCFNL_03872 5.77e-85 cotM - - O ko:K06335 - ko00000 Spore coat protein
HMMFCFNL_03873 5.65e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
HMMFCFNL_03874 3.75e-21 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
HMMFCFNL_03875 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HMMFCFNL_03876 2.53e-118 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HMMFCFNL_03877 9.26e-10 - - - S - - - Fur-regulated basic protein B
HMMFCFNL_03879 1.9e-47 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
HMMFCFNL_03880 4.02e-95 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
HMMFCFNL_03881 1.63e-71 yneQ - - - - - - -
HMMFCFNL_03882 8.97e-65 yneR - - S - - - Belongs to the HesB IscA family
HMMFCFNL_03883 3.86e-122 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HMMFCFNL_03884 1.21e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
HMMFCFNL_03885 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HMMFCFNL_03886 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HMMFCFNL_03887 1.82e-18 - - - - - - - -
HMMFCFNL_03888 8.74e-75 ynfC - - - - - - -
HMMFCFNL_03889 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
HMMFCFNL_03890 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
HMMFCFNL_03892 3.94e-316 ynfF 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
HMMFCFNL_03893 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
HMMFCFNL_03894 1.72e-103 yngA - - S - - - membrane
HMMFCFNL_03895 2.74e-210 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
HMMFCFNL_03896 2.01e-134 yngC - - S - - - membrane-associated protein
HMMFCFNL_03897 7.39e-296 yngD - - S ko:K07097 - ko00000 phosphohydrolase (DHH superfamily)
HMMFCFNL_03898 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HMMFCFNL_03899 1e-173 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
HMMFCFNL_03900 1.65e-212 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
HMMFCFNL_03901 2.4e-41 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
HMMFCFNL_03902 9.36e-317 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
HMMFCFNL_03903 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HMMFCFNL_03904 3.09e-267 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
HMMFCFNL_03905 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
HMMFCFNL_03906 1.01e-82 yngL - - S - - - Protein of unknown function (DUF1360)
HMMFCFNL_03907 0.0 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
HMMFCFNL_03908 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMMFCFNL_03909 8.69e-181 pdaB - - G - - - Polysaccharide deacetylase
HMMFCFNL_03910 5.95e-133 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
HMMFCFNL_03911 1.04e-122 gerD - - - ko:K06294 - ko00000 -
HMMFCFNL_03912 1.1e-255 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HMMFCFNL_03913 9.05e-170 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
HMMFCFNL_03914 2.54e-91 ybaK - - S - - - Protein of unknown function (DUF2521)
HMMFCFNL_03915 4.15e-184 ybaJ - - Q - - - Methyltransferase domain
HMMFCFNL_03916 4.28e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
HMMFCFNL_03917 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HMMFCFNL_03918 2.51e-181 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HMMFCFNL_03919 1.6e-177 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMMFCFNL_03920 5.21e-195 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMMFCFNL_03921 7.5e-200 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMMFCFNL_03922 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
HMMFCFNL_03923 7.01e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMMFCFNL_03924 3.24e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HMMFCFNL_03925 1.09e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HMMFCFNL_03926 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
HMMFCFNL_03927 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HMMFCFNL_03928 2.32e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
HMMFCFNL_03929 2.51e-157 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HMMFCFNL_03930 5.7e-298 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HMMFCFNL_03931 7.32e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
HMMFCFNL_03932 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
HMMFCFNL_03933 9.16e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HMMFCFNL_03934 2.89e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HMMFCFNL_03935 4.47e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HMMFCFNL_03936 3.11e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HMMFCFNL_03937 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HMMFCFNL_03938 7.72e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HMMFCFNL_03939 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HMMFCFNL_03940 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HMMFCFNL_03941 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HMMFCFNL_03942 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
HMMFCFNL_03943 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HMMFCFNL_03944 5.9e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HMMFCFNL_03945 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HMMFCFNL_03946 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HMMFCFNL_03947 2.72e-200 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HMMFCFNL_03948 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HMMFCFNL_03949 7.98e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
HMMFCFNL_03950 7.2e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HMMFCFNL_03951 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
HMMFCFNL_03952 1.9e-232 ybaC - - S - - - Alpha/beta hydrolase family
HMMFCFNL_03953 2.01e-287 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HMMFCFNL_03954 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HMMFCFNL_03955 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HMMFCFNL_03956 6.67e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HMMFCFNL_03957 1.99e-44 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
HMMFCFNL_03958 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMMFCFNL_03959 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMMFCFNL_03960 7.25e-140 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
HMMFCFNL_03961 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HMMFCFNL_03962 4.03e-104 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HMMFCFNL_03963 1.82e-162 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HMMFCFNL_03964 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HMMFCFNL_03965 1.37e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
HMMFCFNL_03966 2.65e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HMMFCFNL_03967 3.27e-149 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
HMMFCFNL_03968 3.31e-114 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
HMMFCFNL_03969 3.52e-173 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HMMFCFNL_03970 3.52e-96 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HMMFCFNL_03971 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HMMFCFNL_03972 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
HMMFCFNL_03973 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HMMFCFNL_03974 2.59e-112 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HMMFCFNL_03975 2.13e-161 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HMMFCFNL_03976 3.65e-252 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
HMMFCFNL_03977 3.8e-251 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HMMFCFNL_03978 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HMMFCFNL_03979 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
HMMFCFNL_03980 7.74e-257 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HMMFCFNL_03981 2.36e-74 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
HMMFCFNL_03982 8.72e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
HMMFCFNL_03983 2.21e-42 csfB - - S - - - Inhibitor of sigma-G Gin
HMMFCFNL_03984 3.83e-132 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
HMMFCFNL_03985 4.84e-258 yaaN - - P - - - Belongs to the TelA family
HMMFCFNL_03986 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
HMMFCFNL_03987 4.67e-146 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HMMFCFNL_03988 1.02e-72 yaaQ - - S - - - protein conserved in bacteria
HMMFCFNL_03989 1.26e-95 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
HMMFCFNL_03990 2.82e-235 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
HMMFCFNL_03991 6.33e-189 yaaT - - S - - - stage 0 sporulation protein
HMMFCFNL_03992 1.53e-56 yabA - - L - - - Involved in initiation control of chromosome replication
HMMFCFNL_03993 1.63e-177 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
HMMFCFNL_03994 1.2e-64 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
HMMFCFNL_03995 2.95e-207 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HMMFCFNL_03996 1.51e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
HMMFCFNL_03997 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HMMFCFNL_03998 5.9e-184 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
HMMFCFNL_03999 4.1e-278 yabE - - T - - - protein conserved in bacteria
HMMFCFNL_04000 1.43e-125 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HMMFCFNL_04001 2.39e-197 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HMMFCFNL_04002 1.11e-198 yabG - - S ko:K06436 - ko00000 peptidase
HMMFCFNL_04003 5.32e-53 veg - - S - - - protein conserved in bacteria
HMMFCFNL_04004 3.96e-37 sspF - - S ko:K06423 - ko00000 DNA topological change
HMMFCFNL_04005 2.34e-207 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HMMFCFNL_04006 4.66e-196 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
HMMFCFNL_04007 3.45e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
HMMFCFNL_04008 2.45e-63 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HMMFCFNL_04009 2.58e-309 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HMMFCFNL_04010 1.22e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HMMFCFNL_04011 4.16e-136 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HMMFCFNL_04012 2.03e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HMMFCFNL_04013 6.36e-54 yabK - - S - - - Peptide ABC transporter permease
HMMFCFNL_04014 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HMMFCFNL_04015 5.88e-121 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
HMMFCFNL_04016 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HMMFCFNL_04017 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HMMFCFNL_04018 4.22e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HMMFCFNL_04019 1.91e-66 yabP - - S - - - Sporulation protein YabP
HMMFCFNL_04020 7.09e-136 yabQ - - S - - - spore cortex biosynthesis protein
HMMFCFNL_04021 4.18e-75 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
HMMFCFNL_04022 2.49e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
HMMFCFNL_04025 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
HMMFCFNL_04026 5.61e-168 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
HMMFCFNL_04027 1.2e-236 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
HMMFCFNL_04028 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HMMFCFNL_04029 4.82e-121 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
HMMFCFNL_04030 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HMMFCFNL_04031 6.92e-189 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HMMFCFNL_04032 9.54e-208 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HMMFCFNL_04033 7.8e-195 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
HMMFCFNL_04034 1.54e-217 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HMMFCFNL_04035 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HMMFCFNL_04036 8.16e-135 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
HMMFCFNL_04037 5.14e-213 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
HMMFCFNL_04038 9.52e-205 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HMMFCFNL_04039 2.2e-79 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HMMFCFNL_04040 4.56e-115 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HMMFCFNL_04041 1.81e-41 yazB - - K - - - transcriptional
HMMFCFNL_04042 1.59e-243 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HMMFCFNL_04043 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
HMMFCFNL_04044 5.3e-49 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
HMMFCFNL_04045 1.55e-42 yaaL - - S - - - Protein of unknown function (DUF2508)
HMMFCFNL_04046 8.53e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HMMFCFNL_04047 8.75e-55 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HMMFCFNL_04048 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HMMFCFNL_04049 1.05e-108 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HMMFCFNL_04050 1.89e-123 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
HMMFCFNL_04051 2.99e-275 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
HMMFCFNL_04052 5.73e-149 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
HMMFCFNL_04053 2.15e-158 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
HMMFCFNL_04055 4.64e-294 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HMMFCFNL_04056 1.66e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HMMFCFNL_04057 3.7e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HMMFCFNL_04058 3.75e-316 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HMMFCFNL_04059 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HMMFCFNL_04060 1.76e-231 yaaC - - S - - - YaaC-like Protein
HMMFCFNL_04062 0.0 - - - Q ko:K15665 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMMFCFNL_04063 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMMFCFNL_04064 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMMFCFNL_04065 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)