ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
MLFELBAE_00001 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
MLFELBAE_00002 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
MLFELBAE_00003 2.14e-198 yloC - - S - - - stress-induced protein
MLFELBAE_00004 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
MLFELBAE_00005 4.91e-144 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
MLFELBAE_00006 2.53e-38 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MLFELBAE_00007 2.18e-287 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MLFELBAE_00008 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MLFELBAE_00009 5e-111 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MLFELBAE_00010 4.76e-224 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MLFELBAE_00011 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MLFELBAE_00012 8.79e-263 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MLFELBAE_00013 3.51e-178 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
MLFELBAE_00014 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
MLFELBAE_00015 6.22e-211 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MLFELBAE_00016 3.42e-150 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
MLFELBAE_00017 1.3e-153 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
MLFELBAE_00018 3.49e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
MLFELBAE_00019 3.65e-78 yloU - - S - - - protein conserved in bacteria
MLFELBAE_00020 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
MLFELBAE_00021 4.15e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
MLFELBAE_00022 4.14e-202 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
MLFELBAE_00023 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MLFELBAE_00024 4.38e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
MLFELBAE_00025 3.14e-229 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MLFELBAE_00026 1.31e-218 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
MLFELBAE_00027 8.61e-168 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
MLFELBAE_00028 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
MLFELBAE_00029 6.09e-174 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MLFELBAE_00030 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
MLFELBAE_00031 1.87e-224 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MLFELBAE_00032 9.73e-179 - - - S - - - Phosphotransferase enzyme family
MLFELBAE_00033 1.97e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MLFELBAE_00034 3.46e-302 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MLFELBAE_00035 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
MLFELBAE_00036 4.9e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
MLFELBAE_00037 3.41e-80 ylqD - - S - - - YlqD protein
MLFELBAE_00038 1.51e-121 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MLFELBAE_00039 8.4e-178 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
MLFELBAE_00040 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MLFELBAE_00041 7.24e-203 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MLFELBAE_00042 8.29e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MLFELBAE_00043 0.0 ylqG - - - - - - -
MLFELBAE_00044 4.88e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
MLFELBAE_00045 2.02e-270 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MLFELBAE_00046 7.59e-214 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MLFELBAE_00047 1.54e-217 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
MLFELBAE_00048 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MLFELBAE_00049 3.83e-314 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MLFELBAE_00050 3.64e-219 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
MLFELBAE_00051 6.07e-120 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MLFELBAE_00052 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MLFELBAE_00053 2.77e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MLFELBAE_00054 2.8e-84 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
MLFELBAE_00055 8.81e-98 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
MLFELBAE_00056 1.51e-50 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
MLFELBAE_00057 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
MLFELBAE_00058 2.48e-229 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MLFELBAE_00059 9.29e-121 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
MLFELBAE_00060 4.97e-307 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
MLFELBAE_00061 2.17e-92 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
MLFELBAE_00062 3.43e-89 ylxF - - S - - - MgtE intracellular N domain
MLFELBAE_00063 1.73e-259 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
MLFELBAE_00064 8.9e-96 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
MLFELBAE_00065 2.79e-179 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
MLFELBAE_00066 7.7e-80 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
MLFELBAE_00067 1.49e-229 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MLFELBAE_00068 1.21e-247 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MLFELBAE_00069 2.12e-77 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
MLFELBAE_00070 9.34e-144 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
MLFELBAE_00071 6.02e-142 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
MLFELBAE_00072 3.15e-51 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
MLFELBAE_00073 5.74e-168 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
MLFELBAE_00074 2.53e-242 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MLFELBAE_00075 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MLFELBAE_00076 3.23e-249 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
MLFELBAE_00077 6.35e-200 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
MLFELBAE_00078 5.8e-248 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
MLFELBAE_00079 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
MLFELBAE_00080 2.49e-105 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
MLFELBAE_00081 3.42e-142 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
MLFELBAE_00082 2.86e-113 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
MLFELBAE_00083 3.96e-177 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLFELBAE_00084 7.11e-95 ylxL - - - - - - -
MLFELBAE_00085 1.74e-167 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
MLFELBAE_00086 1.63e-200 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MLFELBAE_00087 7.09e-164 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
MLFELBAE_00088 1.94e-118 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MLFELBAE_00089 7.76e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MLFELBAE_00090 3.8e-179 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
MLFELBAE_00091 7.68e-274 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MLFELBAE_00092 9.82e-298 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
MLFELBAE_00093 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MLFELBAE_00094 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MLFELBAE_00095 5.66e-106 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
MLFELBAE_00096 4.04e-264 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
MLFELBAE_00097 6.76e-56 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
MLFELBAE_00098 6.16e-63 ylxQ - - J - - - ribosomal protein
MLFELBAE_00099 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MLFELBAE_00100 3.88e-60 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
MLFELBAE_00101 1.03e-73 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MLFELBAE_00102 7.05e-219 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MLFELBAE_00103 1.24e-230 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
MLFELBAE_00104 4.12e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MLFELBAE_00105 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MLFELBAE_00106 1.02e-232 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
MLFELBAE_00107 2.51e-300 mlpA - - S - - - Belongs to the peptidase M16 family
MLFELBAE_00108 2.17e-56 ymxH - - S - - - YlmC YmxH family
MLFELBAE_00109 5.49e-205 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
MLFELBAE_00110 4.75e-138 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
MLFELBAE_00111 7.07e-249 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MLFELBAE_00112 2e-282 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
MLFELBAE_00113 7.2e-202 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MLFELBAE_00114 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MLFELBAE_00115 1.31e-165 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
MLFELBAE_00116 3.66e-41 - - - S - - - YlzJ-like protein
MLFELBAE_00117 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
MLFELBAE_00118 4.48e-172 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
MLFELBAE_00119 9.04e-296 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
MLFELBAE_00120 9.88e-100 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MLFELBAE_00121 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
MLFELBAE_00122 3.22e-306 albE - - S - - - Peptidase M16
MLFELBAE_00123 2.89e-310 ymfH - - S - - - zinc protease
MLFELBAE_00124 8.62e-166 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
MLFELBAE_00125 6.23e-56 ymfJ - - S - - - Protein of unknown function (DUF3243)
MLFELBAE_00126 3.82e-184 ymfK - - S - - - Protein of unknown function (DUF3388)
MLFELBAE_00127 5.76e-177 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
MLFELBAE_00128 1.17e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MLFELBAE_00129 3.27e-294 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
MLFELBAE_00130 2.81e-235 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MLFELBAE_00131 9.05e-278 pbpX - - V - - - Beta-lactamase
MLFELBAE_00132 2.91e-308 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
MLFELBAE_00133 3.72e-196 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
MLFELBAE_00134 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
MLFELBAE_00135 8.3e-251 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
MLFELBAE_00136 4.29e-275 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MLFELBAE_00137 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MLFELBAE_00138 2.11e-88 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
MLFELBAE_00139 7.09e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
MLFELBAE_00140 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MLFELBAE_00141 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MLFELBAE_00142 2.34e-88 - - - L - - - Belongs to the 'phage' integrase family
MLFELBAE_00143 3.97e-49 - - - - - - - -
MLFELBAE_00146 3.33e-165 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
MLFELBAE_00147 4.05e-208 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
MLFELBAE_00148 7.46e-233 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
MLFELBAE_00149 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
MLFELBAE_00150 2.51e-47 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
MLFELBAE_00151 4.42e-310 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
MLFELBAE_00152 4.33e-187 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
MLFELBAE_00153 3.42e-180 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
MLFELBAE_00154 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
MLFELBAE_00155 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
MLFELBAE_00156 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
MLFELBAE_00157 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
MLFELBAE_00158 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
MLFELBAE_00159 7.97e-293 cypA 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
MLFELBAE_00160 2.47e-101 nucB - - M - - - Deoxyribonuclease NucA/NucB
MLFELBAE_00161 1.28e-152 yoaK - - S - - - Membrane
MLFELBAE_00162 2.78e-82 ymzB - - - - - - -
MLFELBAE_00163 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
MLFELBAE_00164 3.03e-06 - - - - - - - -
MLFELBAE_00165 6.85e-164 ymaC - - S - - - Replication protein
MLFELBAE_00166 1.71e-104 ymaD - - O - - - redox protein, regulator of disulfide bond formation
MLFELBAE_00167 7.46e-72 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
MLFELBAE_00168 1.82e-63 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
MLFELBAE_00170 5.96e-77 ymaF - - S - - - YmaF family
MLFELBAE_00171 7.63e-221 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MLFELBAE_00172 9e-46 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
MLFELBAE_00173 6e-59 - - - - - - - -
MLFELBAE_00174 9.42e-29 ymzA - - - - - - -
MLFELBAE_00175 9.34e-88 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
MLFELBAE_00176 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MLFELBAE_00177 5.77e-244 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MLFELBAE_00178 3.18e-141 ymaB - - S - - - MutT family
MLFELBAE_00179 1.07e-148 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
MLFELBAE_00180 1.55e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
MLFELBAE_00181 5.44e-295 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MLFELBAE_00182 6.79e-310 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
MLFELBAE_00183 5.34e-89 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
MLFELBAE_00184 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
MLFELBAE_00186 4.86e-65 - - - - - - - -
MLFELBAE_00188 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
MLFELBAE_00189 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
MLFELBAE_00190 7.75e-279 xylR - - GK - - - ROK family
MLFELBAE_00191 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
MLFELBAE_00192 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
MLFELBAE_00193 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
MLFELBAE_00196 2.21e-27 - - - - - - - -
MLFELBAE_00197 7.2e-152 yobV - - K - - - WYL domain
MLFELBAE_00198 5.71e-71 dinB - - S - - - DinB family
MLFELBAE_00199 1.77e-238 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
MLFELBAE_00200 6.73e-23 - - - - - - - -
MLFELBAE_00201 1.42e-26 yoaW - - - - - - -
MLFELBAE_00202 3.63e-06 ywlA - - S - - - Uncharacterised protein family (UPF0715)
MLFELBAE_00203 6.56e-181 yoaP - - K - - - YoaP-like
MLFELBAE_00204 1.97e-129 - - - J - - - Acetyltransferase (GNAT) domain
MLFELBAE_00206 3.47e-154 - - - S - - - Domain of unknown function (DUF3885)
MLFELBAE_00207 4.15e-258 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLFELBAE_00208 1.65e-152 - - AA10,CBM73 S ko:K03933 - ko00000 Pfam:Chitin_bind_3
MLFELBAE_00209 9.28e-07 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
MLFELBAE_00210 7.48e-85 yoaA 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
MLFELBAE_00211 1.83e-124 yvgO - - - - - - -
MLFELBAE_00213 0.0 yobO - - M - - - Pectate lyase superfamily protein
MLFELBAE_00214 1.49e-102 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
MLFELBAE_00215 1.01e-184 yndL - - S - - - Replication protein
MLFELBAE_00216 1.74e-11 - - - - - - - -
MLFELBAE_00217 1.48e-183 - - - O - - - COG0330 Membrane protease subunits, stomatin prohibitin homologs
MLFELBAE_00218 1.07e-93 yndM - - S - - - Protein of unknown function (DUF2512)
MLFELBAE_00220 7.8e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MLFELBAE_00221 1.01e-67 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
MLFELBAE_00222 4.29e-144 yneB - - L - - - resolvase
MLFELBAE_00223 2.33e-43 ynzC - - S - - - UPF0291 protein
MLFELBAE_00224 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MLFELBAE_00225 1.08e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
MLFELBAE_00226 6.2e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
MLFELBAE_00227 1.97e-33 ynzD - - S - - - Spo0E like sporulation regulatory protein
MLFELBAE_00228 1.28e-163 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
MLFELBAE_00229 7.09e-76 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
MLFELBAE_00230 2.27e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
MLFELBAE_00231 1.18e-98 yneK - - S - - - Protein of unknown function (DUF2621)
MLFELBAE_00232 7.01e-82 cotM - - O ko:K06335 - ko00000 Spore coat protein
MLFELBAE_00233 1.97e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
MLFELBAE_00234 6.2e-22 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
MLFELBAE_00235 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MLFELBAE_00236 3.46e-120 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MLFELBAE_00238 1e-43 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
MLFELBAE_00239 2.94e-97 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
MLFELBAE_00240 7.79e-70 yneQ - - - - - - -
MLFELBAE_00241 2.67e-66 yneR - - S - - - Belongs to the HesB IscA family
MLFELBAE_00242 9.09e-121 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MLFELBAE_00243 9.94e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
MLFELBAE_00244 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MLFELBAE_00245 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MLFELBAE_00246 3.14e-19 - - - - - - - -
MLFELBAE_00247 1.82e-63 ynfC - - - - - - -
MLFELBAE_00248 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
MLFELBAE_00249 7.44e-230 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
MLFELBAE_00250 8.49e-242 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
MLFELBAE_00251 1.84e-147 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
MLFELBAE_00252 1.55e-268 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
MLFELBAE_00253 1.06e-193 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MLFELBAE_00254 1.5e-232 regR - - K ko:K02525 - ko00000,ko03000 transcriptional
MLFELBAE_00255 3.21e-286 exuT - - G ko:K08191,ko:K08194 - ko00000,ko02000 Sugar (and other) transporter
MLFELBAE_00256 3.31e-198 yndG - - S - - - DoxX-like family
MLFELBAE_00257 1.83e-98 - - - S - - - Domain of unknown function (DUF4166)
MLFELBAE_00258 0.0 yndJ - - S - - - YndJ-like protein
MLFELBAE_00260 2.99e-34 - - - - - - - -
MLFELBAE_00262 1.3e-173 - - - S - - - COG0457 FOG TPR repeat
MLFELBAE_00267 4.17e-89 - - - S ko:K02004 - ko00000,ko00002,ko02000 Protein of unknown function (DUF1430)
MLFELBAE_00268 4.96e-83 - - - V ko:K02003,ko:K09810 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MLFELBAE_00271 1.05e-84 - - - S - - - Platelet-activating factor acetylhydrolase, isoform II
MLFELBAE_00272 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
MLFELBAE_00273 1.48e-69 yvlA - - S - - - Domain of unknown function (DUF4870)
MLFELBAE_00274 9.79e-312 - - - T - - - Histidine kinase
MLFELBAE_00275 1.88e-164 - - - T - - - Transcriptional regulatory protein, C terminal
MLFELBAE_00276 2.55e-315 ynfF 3.2.1.136 GH5 G ko:K15924 - ko00000,ko01000 Glycosyl hydrolase family 30 beta sandwich domain
MLFELBAE_00277 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
MLFELBAE_00278 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLFELBAE_00279 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLFELBAE_00280 0.0 nrsA - - Q ko:K15661 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLFELBAE_00281 9.85e-281 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
MLFELBAE_00283 6.52e-175 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
MLFELBAE_00284 4.5e-157 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MLFELBAE_00285 8.91e-162 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MLFELBAE_00286 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
MLFELBAE_00287 1.52e-283 bioI 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
MLFELBAE_00288 1.12e-246 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MLFELBAE_00289 1.83e-167 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MLFELBAE_00290 1.68e-274 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MLFELBAE_00291 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
MLFELBAE_00292 1.34e-185 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
MLFELBAE_00293 2.26e-95 yngA - - S - - - membrane
MLFELBAE_00294 1.52e-207 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
MLFELBAE_00295 5.33e-135 yngC - - S - - - SNARE associated Golgi protein
MLFELBAE_00296 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MLFELBAE_00297 1.18e-176 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
MLFELBAE_00298 6.01e-215 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
MLFELBAE_00299 2.77e-41 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
MLFELBAE_00300 0.0 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
MLFELBAE_00301 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MLFELBAE_00302 4.39e-267 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
MLFELBAE_00303 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
MLFELBAE_00304 1.67e-85 yngL - - S - - - Protein of unknown function (DUF1360)
MLFELBAE_00305 0.0 - - - Q ko:K15656,ko:K15668 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 D-alanine [D-alanyl carrier protein] ligase activity
MLFELBAE_00306 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLFELBAE_00307 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLFELBAE_00308 0.0 - - - Q ko:K15665 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLFELBAE_00309 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLFELBAE_00310 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
MLFELBAE_00311 3.33e-240 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
MLFELBAE_00312 3.69e-312 yoeA - - V - - - MATE efflux family protein
MLFELBAE_00313 7.42e-125 yoeB - - S - - - IseA DL-endopeptidase inhibitor
MLFELBAE_00315 3.97e-125 - - - L - - - Integrase
MLFELBAE_00316 6.69e-47 yoeD - - G - - - Helix-turn-helix domain
MLFELBAE_00317 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
MLFELBAE_00318 4.8e-256 - - - EGP ko:K08164 - ko00000,ko02000 -transporter
MLFELBAE_00319 3.29e-67 - - - K - - - Helix-turn-helix domain
MLFELBAE_00320 9.36e-18 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MLFELBAE_00321 3.04e-200 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
MLFELBAE_00322 3.07e-240 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
MLFELBAE_00323 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
MLFELBAE_00324 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
MLFELBAE_00325 3.04e-204 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
MLFELBAE_00326 3.29e-258 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MLFELBAE_00327 2.93e-182 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MLFELBAE_00328 8.13e-82 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
MLFELBAE_00329 3.49e-160 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
MLFELBAE_00330 6.9e-56 - - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MLFELBAE_00331 9.01e-178 yoxB - - - - - - -
MLFELBAE_00332 6.05e-259 yoaB - - EGP - - - the major facilitator superfamily
MLFELBAE_00333 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
MLFELBAE_00334 2.19e-248 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MLFELBAE_00335 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MLFELBAE_00336 8.57e-22 yoaF - - - - - - -
MLFELBAE_00338 1.1e-126 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MLFELBAE_00339 1.45e-60 - - - - - - - -
MLFELBAE_00340 3.86e-112 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
MLFELBAE_00341 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MLFELBAE_00342 1.49e-70 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
MLFELBAE_00343 1.83e-173 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
MLFELBAE_00344 2.64e-122 yobS - - K - - - Transcriptional regulator
MLFELBAE_00345 6.63e-173 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
MLFELBAE_00346 3.86e-119 yobW - - - - - - -
MLFELBAE_00347 7.69e-73 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
MLFELBAE_00348 1.19e-157 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MLFELBAE_00349 8.99e-116 yozB - - S ko:K08976 - ko00000 membrane
MLFELBAE_00350 2.69e-183 - - - J - - - Protein required for attachment to host cells
MLFELBAE_00351 1.6e-123 yocC - - - - - - -
MLFELBAE_00352 6.44e-239 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
MLFELBAE_00354 6.28e-164 yocH - - M - - - COG1388 FOG LysM repeat
MLFELBAE_00355 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
MLFELBAE_00356 2.32e-144 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MLFELBAE_00358 4.5e-79 yocK - - T - - - general stress protein
MLFELBAE_00359 1.92e-13 yocL - - - - - - -
MLFELBAE_00360 3.51e-13 yocN - - - - - - -
MLFELBAE_00361 2.29e-116 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
MLFELBAE_00362 5.58e-59 yozN - - - - - - -
MLFELBAE_00363 6.36e-50 yocN - - - - - - -
MLFELBAE_00364 5.32e-75 yozO - - S - - - Bacterial PH domain
MLFELBAE_00366 1.35e-42 yozC - - - - - - -
MLFELBAE_00367 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
MLFELBAE_00368 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
MLFELBAE_00369 4.76e-212 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
MLFELBAE_00370 1.45e-298 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MLFELBAE_00371 8.09e-214 yocS - - S ko:K03453 - ko00000 -transporter
MLFELBAE_00372 9.06e-180 - - - S - - - Metallo-beta-lactamase superfamily
MLFELBAE_00373 7.08e-261 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
MLFELBAE_00374 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
MLFELBAE_00375 0.0 yojO - - P - - - Von Willebrand factor
MLFELBAE_00376 4.2e-209 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
MLFELBAE_00377 2.18e-143 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MLFELBAE_00378 1.01e-291 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
MLFELBAE_00379 2.35e-285 - - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
MLFELBAE_00380 9.47e-144 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MLFELBAE_00382 4.62e-308 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
MLFELBAE_00383 1.44e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MLFELBAE_00384 3.71e-161 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
MLFELBAE_00385 8.09e-80 yojF - - S - - - Protein of unknown function (DUF1806)
MLFELBAE_00386 1.05e-30 - - - - - - - -
MLFELBAE_00387 4.21e-210 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
MLFELBAE_00388 4e-105 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
MLFELBAE_00390 1.5e-88 iolK - - S - - - tautomerase
MLFELBAE_00391 1.59e-91 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
MLFELBAE_00392 1.2e-74 yodB - - K - - - transcriptional
MLFELBAE_00393 1.35e-138 yodC - - C - - - nitroreductase
MLFELBAE_00394 2.53e-142 yahD - - S ko:K06999 - ko00000 Carboxylesterase
MLFELBAE_00395 7.66e-222 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
MLFELBAE_00396 1.97e-28 - - - S - - - Protein of unknown function (DUF3311)
MLFELBAE_00397 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MLFELBAE_00398 0.0 - 3.2.1.45 GH30 M ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 ko00000,ko00001,ko01000 Glycosyl hydrolase family 30 beta sandwich domain
MLFELBAE_00399 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MLFELBAE_00400 2.9e-168 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
MLFELBAE_00401 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
MLFELBAE_00402 4.31e-166 yodH - - Q - - - Methyltransferase
MLFELBAE_00403 1.68e-50 yodI - - - - - - -
MLFELBAE_00404 1.83e-191 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
MLFELBAE_00405 1.05e-161 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
MLFELBAE_00407 1.16e-72 yodL - - S - - - YodL-like
MLFELBAE_00408 1.29e-134 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
MLFELBAE_00409 9.77e-34 yozD - - S - - - YozD-like protein
MLFELBAE_00411 1.9e-161 yodN - - - - - - -
MLFELBAE_00412 2.45e-48 yozE - - S - - - Belongs to the UPF0346 family
MLFELBAE_00413 8.43e-64 yokU - - S - - - YokU-like protein, putative antitoxin
MLFELBAE_00414 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
MLFELBAE_00415 2.08e-205 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
MLFELBAE_00416 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
MLFELBAE_00417 2.68e-159 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MLFELBAE_00418 6.87e-161 atoD 2.8.3.8, 2.8.3.9 - I ko:K01034 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MLFELBAE_00419 5.89e-313 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MLFELBAE_00420 3.97e-82 - - - L - - - Bacterial transcription activator, effector binding domain
MLFELBAE_00422 1.34e-183 yiiD - - K ko:K06323 - ko00000 acetyltransferase
MLFELBAE_00423 0.0 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
MLFELBAE_00424 6.96e-64 cgeC - - - ko:K06321 - ko00000 -
MLFELBAE_00425 3.65e-89 cgeA - - - ko:K06319 - ko00000 -
MLFELBAE_00426 7.75e-232 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
MLFELBAE_00427 1.11e-282 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
MLFELBAE_00428 3.54e-95 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
MLFELBAE_00433 2.25e-100 yoqH - - M - - - LysM domain
MLFELBAE_00434 4.42e-251 - - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
MLFELBAE_00436 1.69e-216 - - - S - - - amine dehydrogenase activity
MLFELBAE_00438 3.52e-64 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
MLFELBAE_00439 4.3e-122 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MLFELBAE_00440 1.27e-194 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MLFELBAE_00442 3e-109 - - - G - - - SMI1-KNR4 cell-wall
MLFELBAE_00443 5.15e-109 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
MLFELBAE_00444 0.0 yokA - - L - - - Recombinase
MLFELBAE_00445 1.02e-135 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
MLFELBAE_00446 4.61e-106 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
MLFELBAE_00447 1.2e-133 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MLFELBAE_00448 8.22e-90 ypoP - - K - - - transcriptional
MLFELBAE_00449 7.94e-126 ypmS - - S - - - protein conserved in bacteria
MLFELBAE_00450 4.29e-175 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
MLFELBAE_00451 4.2e-136 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
MLFELBAE_00452 8.98e-55 ypmP - - S - - - Protein of unknown function (DUF2535)
MLFELBAE_00453 4.25e-309 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MLFELBAE_00454 1.05e-226 yplP - - K - - - Transcriptional regulator
MLFELBAE_00455 7.44e-143 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
MLFELBAE_00456 6.97e-150 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MLFELBAE_00457 3.01e-117 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MLFELBAE_00458 3.6e-203 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MLFELBAE_00459 6.48e-148 ypjP - - S - - - YpjP-like protein
MLFELBAE_00460 2.02e-171 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
MLFELBAE_00461 4.8e-99 yphP - - S - - - Belongs to the UPF0403 family
MLFELBAE_00462 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
MLFELBAE_00463 7.72e-202 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
MLFELBAE_00464 1.33e-127 yagB - - S ko:K06950 - ko00000 phosphohydrolase
MLFELBAE_00465 9.63e-114 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
MLFELBAE_00466 2.3e-227 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MLFELBAE_00467 5.21e-275 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
MLFELBAE_00468 5.12e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
MLFELBAE_00469 1.27e-17 degR - - - - - - -
MLFELBAE_00470 1.13e-49 - - - S - - - Protein of unknown function (DUF2564)
MLFELBAE_00471 5.43e-39 ypeQ - - S - - - Zinc-finger
MLFELBAE_00472 1.98e-157 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
MLFELBAE_00473 1.09e-151 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MLFELBAE_00474 5.83e-87 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
MLFELBAE_00476 2.74e-209 ypcP - - L - - - 5'3' exonuclease
MLFELBAE_00477 2.44e-10 - - - - - - - -
MLFELBAE_00478 8.23e-52 ypbS - - S - - - Protein of unknown function (DUF2533)
MLFELBAE_00479 0.0 ypbR - - S - - - Dynamin family
MLFELBAE_00480 1.26e-117 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
MLFELBAE_00481 4.22e-267 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
MLFELBAE_00482 5.69e-137 - - - J - - - Acetyltransferase (GNAT) domain
MLFELBAE_00483 2.21e-66 MGMT - - L ko:K07443 - ko00000 6-O-methylguanine DNA methyltransferase, DNA binding domain
MLFELBAE_00484 1.21e-08 - - - S - - - Bacillus cereus group antimicrobial protein
MLFELBAE_00485 3.5e-42 ydfR - - S - - - Protein of unknown function (DUF421)
MLFELBAE_00486 1.48e-128 yrdC - - Q - - - Isochorismatase family
MLFELBAE_00487 2.23e-07 - - - S - - - Bacillus cereus group antimicrobial protein
MLFELBAE_00488 3.91e-37 - - - K - - - Helix-turn-helix domain
MLFELBAE_00491 2.17e-101 tagE 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
MLFELBAE_00494 2.43e-86 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 Ami_2
MLFELBAE_00495 5.3e-75 - - - S - - - Pfam:Phage_holin_4_1
MLFELBAE_00496 2.4e-07 - - - S - - - Phage uncharacterised protein (Phage_XkdX)
MLFELBAE_00497 0.000763 - - - - - - - -
MLFELBAE_00498 1.33e-118 - - - - - - - -
MLFELBAE_00499 0.0 - - - S - - - Peptidase_G2, IMC autoproteolytic cleavage domain
MLFELBAE_00500 2.29e-288 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
MLFELBAE_00501 1.08e-131 - - - S - - - Phage tail protein
MLFELBAE_00502 0.0 - - - D - - - phage tail tape measure protein
MLFELBAE_00503 6.81e-06 - - - - - - - -
MLFELBAE_00504 9.78e-105 - - - S - - - Phage tail tube protein
MLFELBAE_00506 8.97e-62 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
MLFELBAE_00507 1.34e-54 - - - S - - - Phage head-tail joining protein
MLFELBAE_00508 1.2e-51 - - - S - - - Phage gp6-like head-tail connector protein
MLFELBAE_00509 4.39e-36 - - - - - - - -
MLFELBAE_00510 1.59e-198 - - - S - - - capsid protein
MLFELBAE_00511 9.69e-105 - - - S - - - peptidase activity
MLFELBAE_00512 1.74e-216 - - - S - - - Phage portal protein
MLFELBAE_00513 0.0 - - - S - - - Terminase
MLFELBAE_00514 1.42e-99 - - - L - - - phage terminase small subunit
MLFELBAE_00517 6.21e-25 - - - K - - - Transcriptional regulator
MLFELBAE_00519 8.61e-18 - - - K - - - Transcriptional regulator
MLFELBAE_00521 2.91e-88 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
MLFELBAE_00524 7.1e-89 - - - - - - - -
MLFELBAE_00528 1.07e-28 yqaO - - S - - - Phage-like element PBSX protein XtrA
MLFELBAE_00530 4.56e-78 rusA - - L - - - Endodeoxyribonuclease RusA
MLFELBAE_00532 7.45e-148 yqaM - - L - - - IstB-like ATP binding protein
MLFELBAE_00533 1.46e-100 yqaL - - L - - - DnaD domain protein
MLFELBAE_00535 1.05e-79 pi112 - - L - - - PDDEXK-like domain of unknown function (DUF3799)
MLFELBAE_00536 3.75e-126 - - - - - - - -
MLFELBAE_00540 9.77e-112 - - - - - - - -
MLFELBAE_00541 7.2e-50 - - - K ko:K07741 - ko00000 AntA/AntB antirepressor
MLFELBAE_00542 3.79e-45 - - - - - - - -
MLFELBAE_00543 6.12e-08 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
MLFELBAE_00544 2.3e-18 - - - K - - - Helix-turn-helix XRE-family like proteins
MLFELBAE_00545 1.56e-176 - - - L - - - Belongs to the 'phage' integrase family
MLFELBAE_00546 1.77e-298 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine
MLFELBAE_00547 1.16e-128 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MLFELBAE_00548 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MLFELBAE_00549 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
MLFELBAE_00551 6.91e-31 - - - S - - - YpzG-like protein
MLFELBAE_00552 6.65e-276 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
MLFELBAE_00553 5.52e-61 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MLFELBAE_00554 2.69e-128 ypsA - - S - - - Belongs to the UPF0398 family
MLFELBAE_00555 9.36e-48 cotD - - S ko:K06327 - ko00000 Inner spore coat protein D
MLFELBAE_00557 1.83e-298 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
MLFELBAE_00558 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
MLFELBAE_00559 1.21e-115 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
MLFELBAE_00560 5.09e-93 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
MLFELBAE_00561 3.33e-81 yppG - - S - - - YppG-like protein
MLFELBAE_00565 0.000542 - - - - ko:K06430 - ko00000 -
MLFELBAE_00566 1.35e-237 yppC - - S - - - Protein of unknown function (DUF2515)
MLFELBAE_00567 8.84e-146 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MLFELBAE_00568 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
MLFELBAE_00569 2.11e-118 ypoC - - - - - - -
MLFELBAE_00570 1.02e-157 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MLFELBAE_00571 9.8e-167 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
MLFELBAE_00572 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
MLFELBAE_00573 1.4e-281 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
MLFELBAE_00574 9.65e-105 ypmB - - S - - - protein conserved in bacteria
MLFELBAE_00575 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
MLFELBAE_00576 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
MLFELBAE_00577 2.41e-84 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MLFELBAE_00578 1.15e-201 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MLFELBAE_00579 1.14e-192 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
MLFELBAE_00580 3.67e-229 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MLFELBAE_00581 8.05e-278 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MLFELBAE_00582 1.04e-268 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
MLFELBAE_00583 7.44e-169 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
MLFELBAE_00584 6.19e-94 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
MLFELBAE_00585 9.78e-189 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MLFELBAE_00586 2.47e-74 ypjD - - S - - - Nucleotide pyrophosphohydrolase
MLFELBAE_00587 4.31e-199 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
MLFELBAE_00588 1.42e-289 - 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
MLFELBAE_00589 2.05e-182 ypjB - - S - - - sporulation protein
MLFELBAE_00590 1.03e-133 ypjA - - S - - - membrane
MLFELBAE_00591 4.02e-191 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
MLFELBAE_00592 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
MLFELBAE_00593 2.86e-127 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
MLFELBAE_00594 3.21e-99 ypiF - - S - - - Protein of unknown function (DUF2487)
MLFELBAE_00595 1.06e-128 ypiB - - S - - - Belongs to the UPF0302 family
MLFELBAE_00596 6.15e-298 ypiA - - S - - - COG0457 FOG TPR repeat
MLFELBAE_00597 1.5e-152 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
MLFELBAE_00598 2.04e-66 - - - L - - - transposase activity
MLFELBAE_00599 6.98e-302 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MLFELBAE_00600 1.52e-261 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
MLFELBAE_00601 2.14e-257 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MLFELBAE_00602 6.61e-186 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MLFELBAE_00603 7.35e-292 trpB 4.2.1.20 - E ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MLFELBAE_00604 9.06e-151 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
MLFELBAE_00605 2.46e-169 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
MLFELBAE_00606 2.03e-212 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MLFELBAE_00607 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MLFELBAE_00608 2.93e-79 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
MLFELBAE_00609 7.79e-261 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MLFELBAE_00610 9.75e-276 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MLFELBAE_00611 3.54e-181 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
MLFELBAE_00612 2.35e-101 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
MLFELBAE_00613 2.29e-251 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MLFELBAE_00614 7.76e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MLFELBAE_00615 9.74e-178 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
MLFELBAE_00616 6.23e-47 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
MLFELBAE_00617 6.27e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
MLFELBAE_00618 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MLFELBAE_00619 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MLFELBAE_00620 3.97e-172 yphF - - - - - - -
MLFELBAE_00621 3.25e-23 yphE - - S - - - Protein of unknown function (DUF2768)
MLFELBAE_00622 4.93e-244 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
MLFELBAE_00623 0.0 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
MLFELBAE_00624 8.79e-136 yphA - - - - - - -
MLFELBAE_00625 1.87e-12 - - - S - - - YpzI-like protein
MLFELBAE_00626 1.14e-235 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MLFELBAE_00627 8.14e-264 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
MLFELBAE_00628 2.02e-146 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
MLFELBAE_00629 7.86e-18 - - - S - - - Family of unknown function (DUF5359)
MLFELBAE_00630 3.6e-74 ypfA - - M - - - Flagellar protein YcgR
MLFELBAE_00631 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
MLFELBAE_00632 3.09e-212 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
MLFELBAE_00633 6.4e-156 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
MLFELBAE_00634 1.85e-239 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
MLFELBAE_00635 1.81e-311 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
MLFELBAE_00636 3.35e-137 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MLFELBAE_00637 2.71e-188 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
MLFELBAE_00638 1.92e-111 ypbF - - S - - - Protein of unknown function (DUF2663)
MLFELBAE_00639 2.05e-124 ypbE - - M - - - Lysin motif
MLFELBAE_00640 1.09e-128 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
MLFELBAE_00641 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
MLFELBAE_00642 1.82e-254 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
MLFELBAE_00643 5.88e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
MLFELBAE_00644 6.2e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MLFELBAE_00645 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MLFELBAE_00646 2.02e-249 rsiX - - - - - - -
MLFELBAE_00647 3.22e-135 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MLFELBAE_00648 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MLFELBAE_00649 9.77e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLFELBAE_00650 1.79e-251 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
MLFELBAE_00651 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
MLFELBAE_00652 4.31e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
MLFELBAE_00653 7.38e-168 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MLFELBAE_00654 2.58e-115 spmB - - S ko:K06374 - ko00000 Spore maturation protein
MLFELBAE_00655 3.75e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
MLFELBAE_00656 3.65e-272 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MLFELBAE_00657 6.14e-122 ypuI - - S - - - Protein of unknown function (DUF3907)
MLFELBAE_00658 1.11e-132 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MLFELBAE_00659 2.09e-166 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MLFELBAE_00661 2.83e-121 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
MLFELBAE_00662 2.74e-84 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MLFELBAE_00663 6.92e-106 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MLFELBAE_00664 7.34e-291 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MLFELBAE_00665 6.59e-143 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
MLFELBAE_00666 1.53e-267 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MLFELBAE_00667 4.92e-71 ypuD - - - - - - -
MLFELBAE_00668 3.8e-130 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MLFELBAE_00669 9.6e-106 ccdC1 - - O - - - Protein of unknown function (DUF1453)
MLFELBAE_00670 4.12e-104 ppiB 5.2.1.8 - O ko:K01802,ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MLFELBAE_00671 6.31e-199 ypuA - - S - - - Secreted protein
MLFELBAE_00672 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MLFELBAE_00673 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
MLFELBAE_00674 5.32e-142 - - - S ko:K06407 - ko00000 stage V sporulation protein
MLFELBAE_00675 1.51e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
MLFELBAE_00676 8.19e-244 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
MLFELBAE_00677 9.92e-104 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
MLFELBAE_00678 1.43e-78 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
MLFELBAE_00679 4.7e-143 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
MLFELBAE_00680 6.81e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLFELBAE_00681 4.77e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
MLFELBAE_00682 4.86e-77 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
MLFELBAE_00683 6.08e-274 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MLFELBAE_00684 9.06e-192 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MLFELBAE_00685 4.97e-294 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
MLFELBAE_00686 2.17e-211 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
MLFELBAE_00687 9.51e-51 - - - S - - - Protein of unknown function (DUF4227)
MLFELBAE_00688 4.56e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
MLFELBAE_00689 5.01e-142 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
MLFELBAE_00691 4.38e-47 yqkK - - - - - - -
MLFELBAE_00692 6.84e-31 - - - - - - - -
MLFELBAE_00693 4.12e-310 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
MLFELBAE_00694 2.15e-314 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
MLFELBAE_00695 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
MLFELBAE_00696 5.31e-240 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
MLFELBAE_00697 1.15e-75 ansR - - K - - - Transcriptional regulator
MLFELBAE_00698 6.16e-282 yqxK - - L - - - DNA helicase
MLFELBAE_00699 4.25e-122 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
MLFELBAE_00700 2.01e-10 - - - S - - - Protein of unknown function (DUF3936)
MLFELBAE_00701 5.13e-215 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
MLFELBAE_00702 1.45e-11 yqkE - - S - - - Protein of unknown function (DUF3886)
MLFELBAE_00703 7.06e-227 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
MLFELBAE_00704 7.88e-54 yqkC - - S - - - Protein of unknown function (DUF2552)
MLFELBAE_00705 5.4e-80 yqkB - - S - - - Belongs to the HesB IscA family
MLFELBAE_00706 1.44e-223 yqkA - - K - - - GrpB protein
MLFELBAE_00707 1.71e-80 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
MLFELBAE_00708 2.81e-115 yqjY - - K ko:K06977 - ko00000 acetyltransferase
MLFELBAE_00709 5.69e-300 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MLFELBAE_00710 9.19e-76 - - - S - - - YolD-like protein
MLFELBAE_00712 6.44e-243 yueF - - S - - - transporter activity
MLFELBAE_00714 2.67e-96 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MLFELBAE_00715 4.46e-227 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
MLFELBAE_00716 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
MLFELBAE_00717 3.39e-180 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
MLFELBAE_00718 6.83e-224 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
MLFELBAE_00719 6.79e-186 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MLFELBAE_00720 4.14e-176 - - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
MLFELBAE_00721 3.9e-306 - 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
MLFELBAE_00722 8.08e-281 - 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
MLFELBAE_00723 0.0 - 1.6.5.5 - C ko:K00344 - ko00000,ko01000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
MLFELBAE_00724 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
MLFELBAE_00725 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
MLFELBAE_00726 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
MLFELBAE_00727 7.12e-69 - - - L - - - COG2963 Transposase and inactivated derivatives
MLFELBAE_00730 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
MLFELBAE_00731 2.06e-109 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
MLFELBAE_00732 2.75e-244 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MLFELBAE_00733 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MLFELBAE_00734 2.48e-254 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MLFELBAE_00735 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MLFELBAE_00736 3.1e-149 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MLFELBAE_00737 7.83e-240 ysoA - - H - - - Tetratricopeptide repeat
MLFELBAE_00738 2.18e-287 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MLFELBAE_00739 3.28e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MLFELBAE_00740 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
MLFELBAE_00741 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MLFELBAE_00742 1.79e-137 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
MLFELBAE_00743 1.32e-112 ysxD - - - - - - -
MLFELBAE_00744 1.76e-314 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MLFELBAE_00745 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
MLFELBAE_00746 1.49e-222 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
MLFELBAE_00747 3.98e-184 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
MLFELBAE_00748 3.43e-236 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
MLFELBAE_00749 5.4e-311 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
MLFELBAE_00750 6.4e-299 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
MLFELBAE_00751 1.55e-250 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MLFELBAE_00752 1.53e-35 - - - - - - - -
MLFELBAE_00753 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MLFELBAE_00754 3.78e-307 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
MLFELBAE_00755 1.27e-171 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
MLFELBAE_00756 2.55e-208 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
MLFELBAE_00757 2.36e-130 maf - - D ko:K06287 - ko00000 septum formation protein Maf
MLFELBAE_00758 2.5e-164 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
MLFELBAE_00759 1.06e-234 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
MLFELBAE_00760 4.34e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
MLFELBAE_00761 6.14e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
MLFELBAE_00762 6.85e-155 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MLFELBAE_00763 3.94e-184 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
MLFELBAE_00764 1.39e-188 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
MLFELBAE_00765 3.59e-206 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
MLFELBAE_00766 1.28e-65 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
MLFELBAE_00767 1.42e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
MLFELBAE_00768 7.74e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
MLFELBAE_00769 3.64e-140 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
MLFELBAE_00770 7.1e-311 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MLFELBAE_00771 5.94e-95 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
MLFELBAE_00772 8.16e-206 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
MLFELBAE_00773 2.49e-123 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
MLFELBAE_00774 2.23e-282 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
MLFELBAE_00775 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
MLFELBAE_00776 9.07e-197 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
MLFELBAE_00777 1.73e-271 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MLFELBAE_00778 4.89e-256 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
MLFELBAE_00779 8.92e-61 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MLFELBAE_00781 4.21e-121 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
MLFELBAE_00782 8.13e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MLFELBAE_00783 6.17e-237 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MLFELBAE_00784 9.76e-29 yrzS - - S - - - Protein of unknown function (DUF2905)
MLFELBAE_00785 1.66e-245 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MLFELBAE_00786 2.01e-293 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MLFELBAE_00787 1.03e-50 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
MLFELBAE_00788 9.08e-81 yrzE - - S - - - Protein of unknown function (DUF3792)
MLFELBAE_00789 2.03e-143 yrbG - - S - - - membrane
MLFELBAE_00790 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MLFELBAE_00791 3.45e-68 yrzD - - S - - - Post-transcriptional regulator
MLFELBAE_00792 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MLFELBAE_00793 3.1e-112 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
MLFELBAE_00794 8.73e-60 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
MLFELBAE_00795 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
MLFELBAE_00796 5.1e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MLFELBAE_00797 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MLFELBAE_00798 4.95e-98 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MLFELBAE_00799 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
MLFELBAE_00802 3e-310 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
MLFELBAE_00803 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MLFELBAE_00804 1.18e-178 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
MLFELBAE_00805 3.74e-303 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
MLFELBAE_00806 9.19e-84 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
MLFELBAE_00807 3.63e-270 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
MLFELBAE_00808 1.19e-280 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MLFELBAE_00809 1.12e-23 yrrB - - S - - - COG0457 FOG TPR repeat
MLFELBAE_00810 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MLFELBAE_00811 1.76e-107 yrrD - - S - - - protein conserved in bacteria
MLFELBAE_00812 8.4e-42 yrzR - - - - - - -
MLFELBAE_00813 6.52e-13 - - - S - - - Protein of unknown function (DUF3918)
MLFELBAE_00814 1.87e-139 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MLFELBAE_00815 3.94e-140 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MLFELBAE_00816 3.14e-189 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
MLFELBAE_00817 9.37e-170 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
MLFELBAE_00818 6.63e-237 yrrI - - S - - - AI-2E family transporter
MLFELBAE_00819 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MLFELBAE_00820 1.29e-54 yrzL - - S - - - Belongs to the UPF0297 family
MLFELBAE_00821 2.72e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MLFELBAE_00822 7.2e-61 yrzB - - S - - - Belongs to the UPF0473 family
MLFELBAE_00823 8.08e-259 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MLFELBAE_00824 3.69e-150 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
MLFELBAE_00825 2.2e-222 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
MLFELBAE_00826 1.88e-312 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
MLFELBAE_00827 2.61e-147 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
MLFELBAE_00828 1.62e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MLFELBAE_00829 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
MLFELBAE_00830 5.89e-123 yrrS - - S - - - Protein of unknown function (DUF1510)
MLFELBAE_00831 1.78e-38 yrzA - - S - - - Protein of unknown function (DUF2536)
MLFELBAE_00832 7.23e-155 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
MLFELBAE_00833 5.64e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MLFELBAE_00834 2.28e-218 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
MLFELBAE_00835 5.35e-268 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
MLFELBAE_00836 3.31e-47 yrhC - - S - - - YrhC-like protein
MLFELBAE_00837 4.76e-106 yrhD - - S - - - Protein of unknown function (DUF1641)
MLFELBAE_00838 0.0 yrhE 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
MLFELBAE_00839 1.54e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
MLFELBAE_00840 3.96e-183 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
MLFELBAE_00841 2.37e-07 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
MLFELBAE_00842 9.01e-121 yrhH - - Q - - - methyltransferase
MLFELBAE_00843 4.77e-130 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
MLFELBAE_00844 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
MLFELBAE_00845 7.6e-270 yybF1 - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
MLFELBAE_00846 7.57e-211 yybE - - K - - - Transcriptional regulator
MLFELBAE_00847 1.13e-107 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MLFELBAE_00848 1.98e-232 romA - - S - - - Beta-lactamase superfamily domain
MLFELBAE_00849 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
MLFELBAE_00850 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MLFELBAE_00851 5.09e-240 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
MLFELBAE_00852 2.04e-168 - - - K - - - Helix-turn-helix domain, rpiR family
MLFELBAE_00853 6.84e-186 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
MLFELBAE_00854 1.69e-189 supH - - S - - - hydrolase
MLFELBAE_00855 1.42e-122 - - - S - - - DinB family
MLFELBAE_00856 2.13e-40 - - - K - - - acetyltransferase
MLFELBAE_00857 2.23e-129 yqaC - - F - - - adenylate kinase activity
MLFELBAE_00858 1.76e-130 yrkN - - K - - - Acetyltransferase (GNAT) family
MLFELBAE_00860 8.99e-275 yrkO - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
MLFELBAE_00861 7.69e-159 yrkP - - T ko:K02483 - ko00000,ko02022 Transcriptional regulator
MLFELBAE_00862 2.67e-308 yrkQ - - T - - - Histidine kinase
MLFELBAE_00863 2.15e-90 psiE - - S ko:K13256 - ko00000 Belongs to the PsiE family
MLFELBAE_00864 9.84e-123 - - - K - - - Transcriptional regulator PadR-like family
MLFELBAE_00865 4.85e-203 - - - S - - - Carbohydrate esterase, sialic acid-specific acetylesterase
MLFELBAE_00866 2.4e-20 xkdG - - S - - - Phage capsid family
MLFELBAE_00867 2.72e-91 - - - K - - - MerR family transcriptional regulator
MLFELBAE_00868 2.03e-173 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 Reductase
MLFELBAE_00870 3.94e-27 xkdR - - S - - - Protein of unknown function (DUF2577)
MLFELBAE_00871 4.64e-140 racD 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
MLFELBAE_00872 2.74e-33 xkdS - - S - - - Protein of unknown function (DUF2634)
MLFELBAE_00873 5.58e-161 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLFELBAE_00874 1.28e-276 - - - EGP - - - Transmembrane secretion effector
MLFELBAE_00876 2.92e-138 yqeD - - S - - - SNARE associated Golgi protein
MLFELBAE_00877 8.09e-181 pdaC 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
MLFELBAE_00878 3.59e-178 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
MLFELBAE_00880 5.51e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
MLFELBAE_00881 7.93e-272 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
MLFELBAE_00882 1.15e-198 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MLFELBAE_00883 1.05e-59 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
MLFELBAE_00884 2.89e-140 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MLFELBAE_00885 2.38e-133 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
MLFELBAE_00886 4.65e-80 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MLFELBAE_00887 2.41e-178 yqeM - - Q - - - Methyltransferase
MLFELBAE_00888 1.62e-190 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MLFELBAE_00889 1.19e-135 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
MLFELBAE_00890 3.79e-136 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
MLFELBAE_00891 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
MLFELBAE_00892 3.84e-234 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
MLFELBAE_00893 1.91e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
MLFELBAE_00894 2.51e-260 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MLFELBAE_00895 2.6e-279 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
MLFELBAE_00896 2.1e-71 yqxA - - S - - - Protein of unknown function (DUF3679)
MLFELBAE_00897 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MLFELBAE_00898 5.86e-276 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
MLFELBAE_00899 2.73e-240 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MLFELBAE_00900 5.18e-110 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MLFELBAE_00901 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
MLFELBAE_00902 4.93e-266 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MLFELBAE_00903 6.58e-225 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
MLFELBAE_00904 1.18e-179 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MLFELBAE_00905 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
MLFELBAE_00906 9.26e-200 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
MLFELBAE_00907 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
MLFELBAE_00908 7.84e-91 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
MLFELBAE_00909 5.44e-295 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
MLFELBAE_00910 4.48e-189 yqfA - - S - - - UPF0365 protein
MLFELBAE_00911 1.79e-85 yqfB - - - - - - -
MLFELBAE_00912 3.57e-61 yqfC - - S - - - sporulation protein YqfC
MLFELBAE_00913 1.58e-283 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
MLFELBAE_00914 2.47e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
MLFELBAE_00915 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
MLFELBAE_00916 7.14e-105 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MLFELBAE_00917 5.28e-83 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
MLFELBAE_00918 1.92e-92 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
MLFELBAE_00919 1.42e-214 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MLFELBAE_00920 6e-24 - - - S - - - YqzL-like protein
MLFELBAE_00921 8.73e-186 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
MLFELBAE_00922 5.19e-223 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
MLFELBAE_00923 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
MLFELBAE_00924 5.89e-145 ccpN - - K - - - CBS domain
MLFELBAE_00925 5.46e-192 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MLFELBAE_00926 1.36e-112 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
MLFELBAE_00927 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MLFELBAE_00928 3.97e-255 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MLFELBAE_00929 9.68e-83 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
MLFELBAE_00930 1.35e-158 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
MLFELBAE_00931 7.6e-269 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MLFELBAE_00932 8.66e-227 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MLFELBAE_00933 4.39e-82 yqfQ - - S - - - YqfQ-like protein
MLFELBAE_00934 2.47e-307 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MLFELBAE_00935 1.72e-213 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MLFELBAE_00936 8.63e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
MLFELBAE_00937 5.44e-199 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
MLFELBAE_00938 2.25e-100 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
MLFELBAE_00939 4.09e-142 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
MLFELBAE_00940 3.34e-80 yqfX - - S - - - membrane
MLFELBAE_00941 1.97e-256 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MLFELBAE_00942 1.84e-64 yqfZ - - M ko:K06417 - ko00000 LysM domain
MLFELBAE_00943 1.08e-167 yqgB - - S - - - Protein of unknown function (DUF1189)
MLFELBAE_00944 4.77e-100 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
MLFELBAE_00945 4.22e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
MLFELBAE_00946 2.37e-289 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
MLFELBAE_00947 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
MLFELBAE_00948 2.72e-207 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
MLFELBAE_00949 6.1e-204 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
MLFELBAE_00950 2.91e-199 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
MLFELBAE_00951 1.75e-187 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MLFELBAE_00952 1.9e-187 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MLFELBAE_00953 2.5e-99 yqzC - - S - - - Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MLFELBAE_00954 3.42e-68 yqzD - - - - - - -
MLFELBAE_00955 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
MLFELBAE_00956 1.49e-126 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MLFELBAE_00957 5.38e-11 yqgO - - - - - - -
MLFELBAE_00958 1.21e-274 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
MLFELBAE_00959 1.84e-38 yqgQ - - S - - - Protein conserved in bacteria
MLFELBAE_00960 7.14e-229 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
MLFELBAE_00961 1.24e-284 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
MLFELBAE_00962 1.55e-255 yqgU - - - - - - -
MLFELBAE_00963 2.99e-65 dglA - - S - - - Thiamine-binding protein
MLFELBAE_00964 1.07e-28 yqgW - - S - - - Protein of unknown function (DUF2759)
MLFELBAE_00965 3.45e-157 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
MLFELBAE_00966 4.19e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
MLFELBAE_00967 1.15e-86 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
MLFELBAE_00969 1.44e-190 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MLFELBAE_00970 9.23e-305 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
MLFELBAE_00971 6.43e-239 yqxL - - P - - - Mg2 transporter protein
MLFELBAE_00972 3.84e-258 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MLFELBAE_00973 1.89e-232 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
MLFELBAE_00974 1.82e-65 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
MLFELBAE_00975 2.37e-95 - - - NU ko:K02246,ko:K08084 - ko00000,ko00002,ko02044 Tfp pilus assembly protein FimT
MLFELBAE_00976 2.21e-26 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
MLFELBAE_00977 1.82e-84 comGF - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
MLFELBAE_00978 4.9e-83 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
MLFELBAE_00979 2e-36 yqzE - - S - - - YqzE-like protein
MLFELBAE_00980 6.88e-71 yqzG - - S - - - Protein of unknown function (DUF3889)
MLFELBAE_00981 4.47e-154 yqxM - - - ko:K19433 - ko00000 -
MLFELBAE_00982 1.89e-102 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
MLFELBAE_00983 1.82e-181 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
MLFELBAE_00984 2.75e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
MLFELBAE_00985 2.31e-32 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
MLFELBAE_00986 3.06e-195 yqhG - - S - - - Bacterial protein YqhG of unknown function
MLFELBAE_00987 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
MLFELBAE_00988 9.52e-264 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
MLFELBAE_00989 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MLFELBAE_00990 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MLFELBAE_00991 3.18e-84 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
MLFELBAE_00992 1.58e-204 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
MLFELBAE_00993 5.64e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
MLFELBAE_00994 6.71e-208 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
MLFELBAE_00995 1.54e-82 yqhP - - - - - - -
MLFELBAE_00996 7.33e-221 yqhQ - - S - - - Protein of unknown function (DUF1385)
MLFELBAE_00997 3.99e-118 yqhR - - S - - - Conserved membrane protein YqhR
MLFELBAE_00998 7.05e-248 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
MLFELBAE_00999 6.82e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MLFELBAE_01000 9.89e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
MLFELBAE_01001 2.56e-220 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
MLFELBAE_01002 6.93e-112 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
MLFELBAE_01003 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
MLFELBAE_01004 3.72e-55 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
MLFELBAE_01005 5.23e-261 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
MLFELBAE_01006 1.05e-130 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
MLFELBAE_01007 3.34e-148 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
MLFELBAE_01008 2.24e-93 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
MLFELBAE_01009 3.84e-85 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MLFELBAE_01010 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
MLFELBAE_01011 1.93e-87 yqhY - - S - - - protein conserved in bacteria
MLFELBAE_01012 6.32e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MLFELBAE_01013 3.05e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MLFELBAE_01014 4.1e-310 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MLFELBAE_01015 2.67e-52 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MLFELBAE_01016 4.51e-204 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MLFELBAE_01017 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MLFELBAE_01018 2.51e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
MLFELBAE_01019 4.38e-102 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
MLFELBAE_01020 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
MLFELBAE_01021 8.85e-304 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
MLFELBAE_01022 6.11e-187 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
MLFELBAE_01023 5.23e-277 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MLFELBAE_01026 3.94e-273 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
MLFELBAE_01028 1.15e-145 - - - K - - - Protein of unknown function (DUF1232)
MLFELBAE_01029 1.96e-131 - - - P - - - Probably functions as a manganese efflux pump
MLFELBAE_01031 6.87e-137 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
MLFELBAE_01032 1.9e-175 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
MLFELBAE_01033 1.61e-271 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
MLFELBAE_01034 4.16e-198 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
MLFELBAE_01035 5.06e-260 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
MLFELBAE_01036 8.44e-262 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
MLFELBAE_01037 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
MLFELBAE_01038 4e-205 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MLFELBAE_01039 6.25e-47 yqzF - - S - - - Protein of unknown function (DUF2627)
MLFELBAE_01040 0.0 bkdR - - KT - - - Transcriptional regulator
MLFELBAE_01041 1.67e-195 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
MLFELBAE_01042 2.24e-261 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
MLFELBAE_01043 6.96e-263 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
MLFELBAE_01044 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MLFELBAE_01045 7.89e-222 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MLFELBAE_01046 1.7e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MLFELBAE_01047 2.88e-274 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MLFELBAE_01048 4.26e-219 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MLFELBAE_01049 1.68e-99 yqiW - - S - - - Belongs to the UPF0403 family
MLFELBAE_01050 5.83e-175 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
MLFELBAE_01051 1.04e-141 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
MLFELBAE_01052 2.58e-166 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
MLFELBAE_01053 2.65e-218 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
MLFELBAE_01054 2.61e-123 yqjB - - S - - - protein conserved in bacteria
MLFELBAE_01056 1.89e-95 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
MLFELBAE_01057 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MLFELBAE_01058 1.06e-258 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
MLFELBAE_01059 2.91e-191 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MLFELBAE_01060 1.3e-34 yqzJ - - - - - - -
MLFELBAE_01061 9.49e-302 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MLFELBAE_01062 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MLFELBAE_01063 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MLFELBAE_01064 9.27e-219 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MLFELBAE_01065 1.11e-189 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MLFELBAE_01066 1.27e-247 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
MLFELBAE_01067 7.04e-42 - - - S - - - GlpM protein
MLFELBAE_01068 6.14e-122 nusG1 - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
MLFELBAE_01069 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
MLFELBAE_01072 2.16e-311 - 6.1.3.1, 6.2.1.3, 6.2.1.34 - IQ ko:K00666,ko:K01897,ko:K12508,ko:K22319 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MLFELBAE_01073 1.54e-165 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
MLFELBAE_01074 1.54e-271 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MLFELBAE_01075 2.64e-211 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
MLFELBAE_01076 0.0 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MLFELBAE_01077 5.06e-195 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
MLFELBAE_01078 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MLFELBAE_01079 0.0 - - - M - - - Glycosyltransferase like family 2
MLFELBAE_01080 2.69e-91 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
MLFELBAE_01081 3.69e-183 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MLFELBAE_01082 2.49e-277 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MLFELBAE_01083 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MLFELBAE_01084 1.58e-239 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
MLFELBAE_01085 0.0 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
MLFELBAE_01086 4.46e-254 gerBB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
MLFELBAE_01087 7.36e-273 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
MLFELBAE_01088 0.0 - - - J ko:K07011 - ko00000 Glycosyl transferase family 2
MLFELBAE_01089 3.45e-315 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MLFELBAE_01090 2.3e-229 ywtF_2 - - K - - - Transcriptional regulator
MLFELBAE_01091 1.3e-202 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
MLFELBAE_01092 1.82e-76 yttA - - S - - - Pfam Transposase IS66
MLFELBAE_01093 6.71e-305 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MLFELBAE_01094 4.04e-29 ywtC - - - - - - -
MLFELBAE_01095 1.39e-280 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
MLFELBAE_01096 2.95e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
MLFELBAE_01097 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
MLFELBAE_01098 2.54e-241 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
MLFELBAE_01099 7.28e-246 - - - E - - - Spore germination protein
MLFELBAE_01100 2.62e-262 gerKC - - S - - - Spore germination B3/ GerAC like, C-terminal
MLFELBAE_01101 4.28e-228 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
MLFELBAE_01102 2.94e-203 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MLFELBAE_01103 5.6e-85 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MLFELBAE_01104 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
MLFELBAE_01105 5.37e-205 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MLFELBAE_01106 6.93e-208 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
MLFELBAE_01107 8.33e-116 batE - - T - - - Sh3 type 3 domain protein
MLFELBAE_01108 1.19e-124 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
MLFELBAE_01109 5.71e-191 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
MLFELBAE_01110 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
MLFELBAE_01111 5.35e-215 alsR - - K - - - LysR substrate binding domain
MLFELBAE_01112 1.27e-307 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MLFELBAE_01113 3.43e-163 ywrJ - - - - - - -
MLFELBAE_01114 1.29e-185 cotB - - - ko:K06325 - ko00000 -
MLFELBAE_01115 2.76e-271 cotH - - M ko:K06330 - ko00000 Spore Coat
MLFELBAE_01116 9.51e-25 - - - - - - - -
MLFELBAE_01117 2.33e-143 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MLFELBAE_01118 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
MLFELBAE_01119 3.53e-110 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
MLFELBAE_01120 1.16e-129 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
MLFELBAE_01121 1.74e-113 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
MLFELBAE_01122 2.14e-173 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
MLFELBAE_01123 7.6e-118 - - - - - - - -
MLFELBAE_01124 6.52e-98 - - - S ko:K21494 - ko00000,ko02048 SMI1 / KNR4 family
MLFELBAE_01125 2.74e-85 - - - S ko:K21494 - ko00000,ko02048 SMI1 / KNR4 family (SUKH-1)
MLFELBAE_01126 9.3e-68 - - - S - - - LXG domain of WXG superfamily
MLFELBAE_01127 2.05e-66 - - - - - - - -
MLFELBAE_01128 6.72e-131 - - - L ko:K07497 - ko00000 Integrase core domain
MLFELBAE_01129 4.9e-118 - - - - - - - -
MLFELBAE_01130 0.0 ywqJ - - S - - - Pre-toxin TG
MLFELBAE_01131 2.09e-50 ywqI - - S - - - Family of unknown function (DUF5344)
MLFELBAE_01134 3.4e-190 ywqG - - S - - - Domain of unknown function (DUF1963)
MLFELBAE_01135 2.91e-312 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MLFELBAE_01136 7.45e-182 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
MLFELBAE_01137 5.42e-158 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
MLFELBAE_01138 1.01e-151 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
MLFELBAE_01139 1.74e-21 - - - - - - - -
MLFELBAE_01140 0.0 ywqB - - S - - - SWIM zinc finger
MLFELBAE_01141 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
MLFELBAE_01142 7.5e-202 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
MLFELBAE_01143 4.82e-181 glcR - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
MLFELBAE_01144 5.13e-77 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
MLFELBAE_01145 4.49e-82 ywpG - - - - - - -
MLFELBAE_01146 9.16e-91 ywpF - - S - - - YwpF-like protein
MLFELBAE_01147 7.6e-74 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MLFELBAE_01148 3.15e-98 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MLFELBAE_01149 1.63e-258 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
MLFELBAE_01150 4.64e-188 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
MLFELBAE_01151 1.03e-173 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
MLFELBAE_01152 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
MLFELBAE_01153 5.93e-60 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
MLFELBAE_01154 3.58e-93 ywoH - - K - - - transcriptional
MLFELBAE_01155 2.89e-272 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
MLFELBAE_01156 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
MLFELBAE_01157 2.21e-309 ywoD - - EGP - - - Major facilitator superfamily
MLFELBAE_01158 1.37e-133 yjgF - - Q - - - Isochorismatase family
MLFELBAE_01159 1.32e-291 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
MLFELBAE_01160 1.07e-75 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
MLFELBAE_01161 6e-267 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
MLFELBAE_01162 5.79e-132 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
MLFELBAE_01163 2.7e-94 ywnJ - - S - - - VanZ like family
MLFELBAE_01164 1.31e-188 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
MLFELBAE_01165 2.27e-114 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
MLFELBAE_01167 2.55e-90 ywnF - - S - - - Family of unknown function (DUF5392)
MLFELBAE_01168 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MLFELBAE_01169 8.03e-79 ywnC - - S - - - Family of unknown function (DUF5362)
MLFELBAE_01170 5.3e-157 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
MLFELBAE_01171 3.09e-88 ywnA - - K - - - Transcriptional regulator
MLFELBAE_01172 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
MLFELBAE_01173 1.85e-82 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
MLFELBAE_01174 2.86e-68 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
MLFELBAE_01175 2.94e-17 csbD - - K - - - CsbD-like
MLFELBAE_01176 3.01e-107 ywmF - - S - - - Peptidase M50
MLFELBAE_01177 6.28e-116 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
MLFELBAE_01178 2.18e-245 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MLFELBAE_01179 8.69e-185 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MLFELBAE_01181 1.5e-158 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
MLFELBAE_01182 1.42e-148 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
MLFELBAE_01183 5.51e-240 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
MLFELBAE_01184 7.05e-306 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MLFELBAE_01185 6.86e-174 ywmB - - S - - - TATA-box binding
MLFELBAE_01186 2.25e-45 ywzB - - S - - - membrane
MLFELBAE_01187 1.76e-118 ywmA - - - - - - -
MLFELBAE_01188 8.24e-83 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
MLFELBAE_01189 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MLFELBAE_01190 1.1e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MLFELBAE_01191 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MLFELBAE_01192 1.95e-116 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MLFELBAE_01193 1.66e-82 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MLFELBAE_01194 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MLFELBAE_01195 1.05e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
MLFELBAE_01196 4.49e-80 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
MLFELBAE_01197 2.24e-147 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MLFELBAE_01198 1.7e-300 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MLFELBAE_01199 3.68e-125 ywlG - - S - - - Belongs to the UPF0340 family
MLFELBAE_01200 6.74e-106 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
MLFELBAE_01201 2.43e-100 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MLFELBAE_01202 1.66e-119 mntP - - P - - - Probably functions as a manganese efflux pump
MLFELBAE_01203 6.22e-243 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MLFELBAE_01204 6.01e-99 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
MLFELBAE_01205 2.68e-152 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
MLFELBAE_01206 2.08e-79 ywlA - - S - - - Uncharacterised protein family (UPF0715)
MLFELBAE_01208 1.71e-203 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MLFELBAE_01209 1.11e-244 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MLFELBAE_01210 9.07e-89 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MLFELBAE_01211 1.72e-122 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
MLFELBAE_01212 2.02e-202 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
MLFELBAE_01213 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
MLFELBAE_01214 5.56e-136 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
MLFELBAE_01215 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
MLFELBAE_01216 5.13e-304 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MLFELBAE_01217 1.43e-224 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
MLFELBAE_01218 5.55e-304 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MLFELBAE_01219 2.22e-144 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MLFELBAE_01220 5.51e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
MLFELBAE_01221 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
MLFELBAE_01222 4.7e-120 ywjG - - S - - - Domain of unknown function (DUF2529)
MLFELBAE_01223 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MLFELBAE_01224 1.39e-74 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MLFELBAE_01225 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
MLFELBAE_01226 5.5e-282 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
MLFELBAE_01227 1.1e-232 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
MLFELBAE_01228 1.13e-58 ywjC - - - - - - -
MLFELBAE_01229 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
MLFELBAE_01230 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MLFELBAE_01231 3.38e-133 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
MLFELBAE_01232 1.45e-159 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
MLFELBAE_01233 2.19e-124 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
MLFELBAE_01234 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
MLFELBAE_01235 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MLFELBAE_01236 2.05e-109 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
MLFELBAE_01237 1.51e-178 ywiC - - S - - - YwiC-like protein
MLFELBAE_01238 1.33e-167 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
MLFELBAE_01239 2.47e-272 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
MLFELBAE_01240 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
MLFELBAE_01241 1.14e-96 ywiB - - S - - - protein conserved in bacteria
MLFELBAE_01242 2.26e-304 ywhL - - CO - - - amine dehydrogenase activity
MLFELBAE_01243 2.51e-256 ywhK - - CO - - - amine dehydrogenase activity
MLFELBAE_01244 2.04e-100 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
MLFELBAE_01246 9.15e-41 ydcG - - K ko:K07729 - ko00000,ko03000 sequence-specific DNA binding
MLFELBAE_01247 9.81e-45 - - - - - - - -
MLFELBAE_01249 1.15e-98 - - - CP - - - Membrane
MLFELBAE_01252 4.95e-214 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
MLFELBAE_01253 1.58e-203 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MLFELBAE_01254 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
MLFELBAE_01255 1.2e-26 - - - - - - - -
MLFELBAE_01256 5.29e-121 ywhD - - S - - - YwhD family
MLFELBAE_01257 3.84e-153 ywhC - - S - - - Peptidase family M50
MLFELBAE_01258 2.37e-34 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
MLFELBAE_01259 9.43e-90 ywhA - - K - - - Transcriptional regulator
MLFELBAE_01260 1.91e-313 potE5 - - E ko:K03294 - ko00000 C-terminus of AA_permease
MLFELBAE_01261 2.02e-115 ywgA - - - ko:K09388 - ko00000 -
MLFELBAE_01262 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
MLFELBAE_01263 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
MLFELBAE_01264 2.89e-144 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
MLFELBAE_01265 4.58e-69 - - - K ko:K10947 - ko00000,ko03000 PadR family transcriptional regulator
MLFELBAE_01266 4.59e-121 - - - S - - - membrane
MLFELBAE_01267 3.71e-208 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MLFELBAE_01268 4.2e-215 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC transporter (permease)
MLFELBAE_01271 8.13e-239 - - - - - - - -
MLFELBAE_01273 9.14e-204 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
MLFELBAE_01274 2.63e-209 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
MLFELBAE_01275 2.3e-211 - - - S - - - Conserved hypothetical protein 698
MLFELBAE_01276 2.03e-225 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
MLFELBAE_01277 4.87e-187 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
MLFELBAE_01278 2.94e-181 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
MLFELBAE_01279 3.82e-298 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
MLFELBAE_01280 8.14e-265 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
MLFELBAE_01281 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
MLFELBAE_01282 8.05e-181 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLFELBAE_01283 1.19e-176 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
MLFELBAE_01284 5.69e-146 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
MLFELBAE_01285 1.65e-285 ywfA - - EGP - - - -transporter
MLFELBAE_01286 1.4e-264 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
MLFELBAE_01287 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
MLFELBAE_01288 0.0 rocB - - E - - - arginine degradation protein
MLFELBAE_01289 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
MLFELBAE_01290 3.15e-314 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
MLFELBAE_01291 5.97e-196 - - - T - - - Histidine kinase
MLFELBAE_01292 1.8e-153 - - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLFELBAE_01293 4.23e-28 - - - K ko:K06284 - ko00000,ko03000 AbrB family
MLFELBAE_01294 1.65e-69 - - - S - - - Putative adhesin
MLFELBAE_01295 9.11e-132 - - - S - - - ABC-2 family transporter protein
MLFELBAE_01296 1e-205 bcrA5 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MLFELBAE_01298 3.5e-160 - - - V - - - ABC transporter permease
MLFELBAE_01299 0.0 nrpS2 - - Q - - - AMP-binding enzyme C-terminal domain
MLFELBAE_01300 0.0 nrpS2 - - Q - - - Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLFELBAE_01301 0.0 - - - Q ko:K15654,ko:K15664 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 TIGRFAM amino acid adenylation domain
MLFELBAE_01302 1.15e-112 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
MLFELBAE_01303 2.25e-206 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MLFELBAE_01304 7.47e-233 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MLFELBAE_01305 5.67e-177 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MLFELBAE_01306 2.15e-237 spsG - - M - - - Spore Coat
MLFELBAE_01307 4.8e-170 spsF - - M ko:K07257 - ko00000 Spore Coat
MLFELBAE_01308 2.89e-273 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
MLFELBAE_01309 1.24e-201 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
MLFELBAE_01310 3.42e-280 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
MLFELBAE_01311 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
MLFELBAE_01312 1.29e-183 spsA - - M - - - Spore Coat
MLFELBAE_01313 1.49e-89 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
MLFELBAE_01314 2.17e-76 ywdK - - S - - - small membrane protein
MLFELBAE_01315 3.96e-293 ywdJ - - F - - - Xanthine uracil
MLFELBAE_01316 3.7e-61 ywdI - - S - - - Family of unknown function (DUF5327)
MLFELBAE_01317 7.22e-171 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MLFELBAE_01318 6.93e-194 ywdF - - S - - - Glycosyltransferase like family 2
MLFELBAE_01320 2e-115 ywdD - - - - - - -
MLFELBAE_01321 1.6e-75 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
MLFELBAE_01322 4.13e-187 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
MLFELBAE_01323 3.52e-26 ywdA - - - - - - -
MLFELBAE_01324 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
MLFELBAE_01325 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MLFELBAE_01326 4.68e-196 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
MLFELBAE_01328 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MLFELBAE_01329 6.66e-236 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLFELBAE_01330 3.28e-178 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
MLFELBAE_01331 1.58e-263 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
MLFELBAE_01332 6.77e-100 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
MLFELBAE_01333 2.54e-51 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
MLFELBAE_01334 8.22e-85 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
MLFELBAE_01335 4.91e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
MLFELBAE_01336 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MLFELBAE_01337 2.21e-228 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
MLFELBAE_01338 5.74e-48 ydaS - - S - - - membrane
MLFELBAE_01339 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
MLFELBAE_01340 2.94e-274 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MLFELBAE_01341 3.45e-81 gtcA - - S - - - GtrA-like protein
MLFELBAE_01342 6.43e-146 - - - K - - - Bacterial regulatory proteins, tetR family
MLFELBAE_01344 7.5e-168 - - - H - - - Methionine biosynthesis protein MetW
MLFELBAE_01345 4.9e-172 - - - S - - - Streptomycin biosynthesis protein StrF
MLFELBAE_01346 5.99e-143 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
MLFELBAE_01347 1.54e-309 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
MLFELBAE_01348 6.77e-145 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MLFELBAE_01349 2.25e-176 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MLFELBAE_01350 4.83e-202 ywbI - - K - - - Transcriptional regulator
MLFELBAE_01351 9.02e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
MLFELBAE_01352 6.47e-144 ywbG - - M - - - effector of murein hydrolase
MLFELBAE_01353 2.61e-37 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
MLFELBAE_01354 4.85e-182 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
MLFELBAE_01355 1.37e-216 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
MLFELBAE_01356 1.53e-286 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
MLFELBAE_01357 1.51e-87 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
MLFELBAE_01358 3.28e-315 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MLFELBAE_01359 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MLFELBAE_01360 2.56e-208 gspA - - M - - - General stress
MLFELBAE_01361 4.35e-150 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
MLFELBAE_01362 3.08e-214 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
MLFELBAE_01363 7.08e-18 - - - S - - - D-Ala-teichoic acid biosynthesis protein
MLFELBAE_01364 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLFELBAE_01365 7.34e-293 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
MLFELBAE_01366 1.96e-49 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLFELBAE_01367 3.76e-290 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MLFELBAE_01368 1.35e-261 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
MLFELBAE_01369 8.66e-310 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
MLFELBAE_01371 2.56e-309 ydhD - - M - - - Glycosyl hydrolase
MLFELBAE_01372 4.86e-128 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
MLFELBAE_01373 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MLFELBAE_01374 1.87e-170 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
MLFELBAE_01375 2.21e-190 yojH - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MLFELBAE_01376 2.88e-223 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MLFELBAE_01377 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MLFELBAE_01378 2.61e-154 nsr - - T - - - COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
MLFELBAE_01379 2.8e-277 - - - EGP ko:K05820 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
MLFELBAE_01380 1e-180 - - - M - - - PFAM Collagen triple helix repeat (20 copies)
MLFELBAE_01381 6.09e-276 - - - M - - - Glycosyl transferase family 2
MLFELBAE_01383 1e-83 - - - D - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MLFELBAE_01384 5.52e-92 ohrB - - O - - - Organic hydroperoxide resistance protein
MLFELBAE_01385 1.2e-111 ohrR - - K - - - COG1846 Transcriptional regulators
MLFELBAE_01386 6.87e-93 ohrA - - O - - - Organic hydroperoxide resistance protein
MLFELBAE_01387 1.37e-290 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MLFELBAE_01388 1.25e-261 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MLFELBAE_01389 5.81e-218 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
MLFELBAE_01390 1.04e-65 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
MLFELBAE_01391 9.78e-69 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
MLFELBAE_01392 1.28e-130 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MLFELBAE_01393 8.79e-120 ykhA - - I - - - Acyl-CoA hydrolase
MLFELBAE_01394 6.95e-203 ykgA - - E - - - Amidinotransferase
MLFELBAE_01395 2.07e-263 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
MLFELBAE_01396 1.34e-230 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MLFELBAE_01397 7.95e-220 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MLFELBAE_01398 7.75e-258 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
MLFELBAE_01399 1.68e-227 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
MLFELBAE_01400 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MLFELBAE_01401 2.26e-243 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MLFELBAE_01402 6.59e-227 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLFELBAE_01403 5.65e-204 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLFELBAE_01404 4.36e-200 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
MLFELBAE_01406 0.0 yubD - - P - - - Major Facilitator Superfamily
MLFELBAE_01407 4.55e-277 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MLFELBAE_01409 1.56e-229 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
MLFELBAE_01410 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MLFELBAE_01411 3.43e-234 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
MLFELBAE_01412 2.3e-312 steT - - E ko:K03294 - ko00000 amino acid
MLFELBAE_01413 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
MLFELBAE_01414 7.07e-226 pit - - P ko:K03306 - ko00000 phosphate transporter
MLFELBAE_01415 1.89e-172 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
MLFELBAE_01416 2.53e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
MLFELBAE_01417 5.16e-217 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
MLFELBAE_01418 4.7e-52 xhlB - - S - - - SPP1 phage holin
MLFELBAE_01419 1.11e-50 xhlA - - S - - - Haemolysin XhlA
MLFELBAE_01420 5e-175 xepA - - - - - - -
MLFELBAE_01421 5.6e-41 xkdX - - - - - - -
MLFELBAE_01423 6.69e-83 - - - - - - - -
MLFELBAE_01424 3.63e-37 - - - - - - - -
MLFELBAE_01425 7.1e-113 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
MLFELBAE_01426 7.58e-213 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
MLFELBAE_01427 2.86e-76 xkdS - - S - - - Protein of unknown function (DUF2634)
MLFELBAE_01428 2.51e-43 xkdR - - S - - - Protein of unknown function (DUF2577)
MLFELBAE_01429 1.87e-206 xkdQ - - G - - - NLP P60 protein
MLFELBAE_01430 6.56e-145 xkdP - - S - - - Lysin motif
MLFELBAE_01431 2.75e-286 xkdO - - L - - - Transglycosylase SLT domain
MLFELBAE_01432 4.33e-27 - - - - - - - -
MLFELBAE_01433 7.28e-96 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
MLFELBAE_01434 8.21e-97 xkdM - - S - - - Phage tail tube protein
MLFELBAE_01435 6.61e-287 xkdK - - S - - - Phage tail sheath C-terminal domain
MLFELBAE_01436 1.57e-20 - - - - - - - -
MLFELBAE_01437 1.05e-74 xkdJ - - - - - - -
MLFELBAE_01438 2.94e-78 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
MLFELBAE_01439 5.78e-56 - - - S - - - Domain of unknown function (DUF3599)
MLFELBAE_01440 2.17e-61 yqbG - - S - - - Protein of unknown function (DUF3199)
MLFELBAE_01441 8.3e-203 xkdG - - S - - - Phage capsid family
MLFELBAE_01442 8.8e-119 xkdF3 - - L - - - Putative phage serine protease XkdF
MLFELBAE_01443 3.36e-304 xkdE3 - - S - - - portal protein
MLFELBAE_01444 2.36e-263 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
MLFELBAE_01445 4.8e-140 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
MLFELBAE_01446 3.05e-110 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
MLFELBAE_01450 8.78e-196 xkdC - - L - - - Bacterial dnaA protein
MLFELBAE_01452 3.78e-74 xre - - K - - - Helix-turn-helix XRE-family like proteins
MLFELBAE_01453 1.54e-143 xkdA - - E - - - IrrE N-terminal-like domain
MLFELBAE_01454 7.99e-189 yjqC - - P ko:K07217 - ko00000 Catalase
MLFELBAE_01455 8.47e-141 yjqB - - S - - - phage-related replication protein
MLFELBAE_01456 9.51e-81 yjqA - - S - - - Bacterial PH domain
MLFELBAE_01457 2.37e-221 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
MLFELBAE_01459 2.68e-275 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
MLFELBAE_01460 1.02e-103 yjoA - - S - - - DinB family
MLFELBAE_01461 3.21e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
MLFELBAE_01462 0.0 uxaA 4.2.1.7 - G ko:K01685 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
MLFELBAE_01463 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
MLFELBAE_01464 1.24e-235 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
MLFELBAE_01465 0.0 - - - G ko:K03292 - ko00000 symporter YjmB
MLFELBAE_01466 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
MLFELBAE_01467 6.15e-280 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
MLFELBAE_01468 1.7e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
MLFELBAE_01469 1.22e-118 yjlB - - S - - - Cupin domain
MLFELBAE_01470 3.94e-225 yjlA - - EG - - - Putative multidrug resistance efflux transporter
MLFELBAE_01471 8.84e-166 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 Belongs to the ABC transporter superfamily
MLFELBAE_01472 2.79e-156 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
MLFELBAE_01473 3.09e-182 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
MLFELBAE_01474 1.73e-40 - - - - - - - -
MLFELBAE_01475 9.09e-281 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MLFELBAE_01476 6.01e-287 yjiB 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
MLFELBAE_01477 3.12e-117 yjgD - - S - - - Protein of unknown function (DUF1641)
MLFELBAE_01478 0.0 - 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
MLFELBAE_01479 1.43e-131 yjgB - - S - - - Domain of unknown function (DUF4309)
MLFELBAE_01480 1.8e-91 yjgA - - T - - - Protein of unknown function (DUF2809)
MLFELBAE_01481 1.91e-31 yjfB - - S - - - Putative motility protein
MLFELBAE_01483 2.48e-136 - - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
MLFELBAE_01486 3.55e-162 - - - S - - - Haloacid dehalogenase-like hydrolase
MLFELBAE_01487 2.21e-178 yulB - - K ko:K02530 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
MLFELBAE_01488 0.0 lacG 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MLFELBAE_01489 8.91e-67 celC 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MLFELBAE_01490 0.0 lacE 2.7.1.207 - G ko:K02761,ko:K02787,ko:K02788 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MLFELBAE_01491 5.44e-277 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MLFELBAE_01492 5.12e-243 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
MLFELBAE_01493 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
MLFELBAE_01494 2.69e-281 yvfO 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
MLFELBAE_01495 1.06e-106 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MLFELBAE_01496 0.0 yfjF - - EGP - - - Belongs to the major facilitator superfamily
MLFELBAE_01497 4.44e-61 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
MLFELBAE_01498 8.5e-213 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
MLFELBAE_01500 0.0 - - - S - - - Bacterial EndoU nuclease
MLFELBAE_01501 1.22e-74 - - - - - - - -
MLFELBAE_01502 6.83e-23 - - - - - - - -
MLFELBAE_01503 3.4e-54 - - - - - - - -
MLFELBAE_01504 1.26e-90 - - - S - - - Protein of unknown function (DUF3800)
MLFELBAE_01505 4.23e-249 - - - M - - - nucleic acid phosphodiester bond hydrolysis
MLFELBAE_01506 8.37e-39 - - - S - - - SMI1-KNR4 cell-wall
MLFELBAE_01509 5.37e-251 - - - M - - - nucleic acid phosphodiester bond hydrolysis
MLFELBAE_01511 2.1e-29 - - - - - - - -
MLFELBAE_01512 6.35e-27 - - - - - - - -
MLFELBAE_01514 8.08e-280 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
MLFELBAE_01515 3.37e-272 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
MLFELBAE_01516 1.23e-164 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
MLFELBAE_01517 5.73e-120 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
MLFELBAE_01518 1.05e-97 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MLFELBAE_01520 1.76e-47 - - - K - - - SpoVT / AbrB like domain
MLFELBAE_01521 2.48e-171 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
MLFELBAE_01522 1.53e-158 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
MLFELBAE_01523 2.19e-164 blm 3.5.2.6 - S ko:K17837 ko01501,map01501 ko00000,ko00001,ko01000 Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
MLFELBAE_01524 1.23e-48 - - - - - - - -
MLFELBAE_01525 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
MLFELBAE_01526 2.57e-51 spoVIF - - S - - - Stage VI sporulation protein F
MLFELBAE_01527 5.69e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
MLFELBAE_01530 2.05e-73 yjcA - - S - - - Protein of unknown function (DUF1360)
MLFELBAE_01531 2.67e-68 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
MLFELBAE_01532 8.38e-36 cotW - - - ko:K06341 - ko00000 -
MLFELBAE_01533 4.33e-99 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
MLFELBAE_01534 1.61e-116 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
MLFELBAE_01535 9.62e-105 cotZ - - S ko:K06344 - ko00000 Spore coat protein
MLFELBAE_01536 1.16e-121 yjbX - - S - - - Spore coat protein
MLFELBAE_01537 6.85e-180 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
MLFELBAE_01538 1.83e-190 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
MLFELBAE_01539 1.36e-241 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MLFELBAE_01540 1.81e-173 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
MLFELBAE_01541 5.5e-42 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 Thiamine biosynthesis
MLFELBAE_01542 9.62e-270 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
MLFELBAE_01543 1.63e-138 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
MLFELBAE_01544 2.71e-177 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MLFELBAE_01545 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MLFELBAE_01546 5.27e-184 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
MLFELBAE_01547 1.65e-211 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
MLFELBAE_01548 2.07e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MLFELBAE_01549 9.01e-139 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
MLFELBAE_01550 3.5e-81 yjbL - - S - - - Belongs to the UPF0738 family
MLFELBAE_01551 4.23e-129 yjbK - - S - - - protein conserved in bacteria
MLFELBAE_01552 2.56e-151 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MLFELBAE_01553 7.06e-93 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
MLFELBAE_01554 2.46e-219 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
MLFELBAE_01555 1.28e-26 - - - - - - - -
MLFELBAE_01556 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
MLFELBAE_01557 8.1e-282 coiA - - S ko:K06198 - ko00000 Competence protein
MLFELBAE_01558 9.78e-150 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MLFELBAE_01559 5.59e-141 yjbE - - P - - - Integral membrane protein TerC family
MLFELBAE_01560 2.47e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MLFELBAE_01561 4.4e-132 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MLFELBAE_01562 1.22e-295 - - - S - - - Putative glycosyl hydrolase domain
MLFELBAE_01563 2.19e-220 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MLFELBAE_01564 8.69e-256 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MLFELBAE_01565 3.59e-210 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLFELBAE_01566 2.53e-213 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLFELBAE_01567 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MLFELBAE_01568 2.51e-234 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
MLFELBAE_01569 5.28e-189 yjbA - - S - - - Belongs to the UPF0736 family
MLFELBAE_01570 3.87e-209 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLFELBAE_01571 4.24e-219 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLFELBAE_01572 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
MLFELBAE_01573 7.23e-238 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MLFELBAE_01574 1.45e-232 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MLFELBAE_01575 1.84e-190 yjaZ - - O - - - Zn-dependent protease
MLFELBAE_01576 5.48e-300 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MLFELBAE_01577 3.78e-220 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MLFELBAE_01578 2.82e-44 yjzB - - - - - - -
MLFELBAE_01579 6.46e-37 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
MLFELBAE_01580 4.67e-213 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
MLFELBAE_01581 9.68e-134 yjaV - - - - - - -
MLFELBAE_01582 2.14e-176 yjaU - - I - - - carboxylic ester hydrolase activity
MLFELBAE_01583 1.06e-32 yjzD - - S - - - Protein of unknown function (DUF2929)
MLFELBAE_01584 7.21e-39 yjzC - - S - - - YjzC-like protein
MLFELBAE_01585 2.89e-225 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MLFELBAE_01586 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
MLFELBAE_01587 2.41e-259 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
MLFELBAE_01588 4.84e-278 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
MLFELBAE_01589 8.95e-176 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
MLFELBAE_01590 5.39e-292 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MLFELBAE_01591 1.01e-252 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MLFELBAE_01592 1.18e-121 yitZ - - G - - - Major Facilitator Superfamily
MLFELBAE_01593 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
MLFELBAE_01594 1.08e-101 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
MLFELBAE_01595 3.26e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
MLFELBAE_01596 3.05e-186 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
MLFELBAE_01597 1.52e-198 - 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
MLFELBAE_01598 1.49e-11 - - - - - - - -
MLFELBAE_01599 1.5e-36 - - - S - - - Protein of unknown function (DUF3813)
MLFELBAE_01600 6.41e-106 ipi - - S - - - Intracellular proteinase inhibitor
MLFELBAE_01601 1.61e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
MLFELBAE_01602 5.28e-201 yitS - - S - - - protein conserved in bacteria
MLFELBAE_01604 4.92e-305 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
MLFELBAE_01605 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
MLFELBAE_01606 2.66e-222 - - - S ko:K07335 - ko00000 ABC transporter substrate-binding protein PnrA-like
MLFELBAE_01607 1.59e-206 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
MLFELBAE_01608 6.39e-79 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
MLFELBAE_01609 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
MLFELBAE_01610 3.78e-106 - - - S - - - Acetyltransferase (GNAT) domain
MLFELBAE_01611 6.14e-108 yisX - - S - - - Pentapeptide repeats (9 copies)
MLFELBAE_01612 3.38e-239 yisV - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MLFELBAE_01613 8.48e-96 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
MLFELBAE_01614 3.11e-116 yisT - - S - - - DinB family
MLFELBAE_01615 2.04e-66 - - - L - - - transposase activity
MLFELBAE_01616 1.44e-150 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
MLFELBAE_01617 1.35e-205 yisR - - K - - - Transcriptional regulator
MLFELBAE_01618 1.84e-311 yisQ - - V - - - Mate efflux family protein
MLFELBAE_01619 6.59e-172 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
MLFELBAE_01620 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
MLFELBAE_01621 1.59e-125 yisN - - S - - - Protein of unknown function (DUF2777)
MLFELBAE_01622 2.22e-78 yisL - - S - - - UPF0344 protein
MLFELBAE_01623 1.54e-218 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
MLFELBAE_01624 2.25e-11 yisI - - S - - - Spo0E like sporulation regulatory protein
MLFELBAE_01625 1.28e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
MLFELBAE_01626 6.59e-48 gerPB - - S ko:K06300 - ko00000 cell differentiation
MLFELBAE_01627 3.46e-108 gerPC - - S ko:K06301 - ko00000 Spore germination protein
MLFELBAE_01628 3e-33 gerPD - - S ko:K06302 - ko00000 Spore germination protein
MLFELBAE_01629 6.55e-84 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
MLFELBAE_01630 6.66e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
MLFELBAE_01631 1.53e-66 yisB - - V - - - COG1403 Restriction endonuclease
MLFELBAE_01632 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
MLFELBAE_01633 5.49e-282 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MLFELBAE_01634 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
MLFELBAE_01635 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
MLFELBAE_01636 1.27e-160 ydfS - - S - - - Protein of unknown function (DUF421)
MLFELBAE_01637 7.28e-122 yhjR - - S - - - Rubrerythrin
MLFELBAE_01638 2.72e-142 - - - K - - - QacR-like protein, C-terminal region
MLFELBAE_01639 2.27e-269 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
MLFELBAE_01640 1.7e-262 yhjN - - S ko:K07120 - ko00000 membrane
MLFELBAE_01641 4.89e-122 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
MLFELBAE_01642 0.0 yhjG - - CH - - - FAD binding domain
MLFELBAE_01643 9.51e-119 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MLFELBAE_01644 1.64e-144 yhjE - - S - - - SNARE associated Golgi protein
MLFELBAE_01645 4.12e-79 yhjD - - - - - - -
MLFELBAE_01646 1.37e-37 yhjC - - S - - - Protein of unknown function (DUF3311)
MLFELBAE_01647 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MLFELBAE_01648 2.64e-63 - - - S - - - Belongs to the UPF0145 family
MLFELBAE_01649 1.23e-57 yhjA - - S - - - Excalibur calcium-binding domain
MLFELBAE_01650 4.26e-161 yrpD - - S - - - Domain of unknown function, YrpD
MLFELBAE_01651 2.29e-103 - - - S - - - MepB protein
MLFELBAE_01652 3.9e-79 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
MLFELBAE_01653 1.09e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
MLFELBAE_01654 1.15e-43 yhzC - - S - - - IDEAL
MLFELBAE_01655 1.92e-204 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLFELBAE_01656 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
MLFELBAE_01657 1.13e-276 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
MLFELBAE_01658 1.86e-116 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
MLFELBAE_01659 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
MLFELBAE_01660 2.04e-252 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
MLFELBAE_01661 1.48e-134 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
MLFELBAE_01662 3.7e-201 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
MLFELBAE_01663 3.46e-265 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MLFELBAE_01664 6.42e-301 yhfN - - O - - - Peptidase M48
MLFELBAE_01665 2.38e-86 yhfM - - - - - - -
MLFELBAE_01666 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
MLFELBAE_01667 2.21e-143 yhfK - - GM - - - NmrA-like family
MLFELBAE_01668 6.47e-242 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
MLFELBAE_01669 1.7e-182 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
MLFELBAE_01671 3.43e-282 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MLFELBAE_01672 3.65e-251 yhfE - - G - - - peptidase M42
MLFELBAE_01674 5.92e-235 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MLFELBAE_01675 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
MLFELBAE_01676 3.63e-130 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
MLFELBAE_01677 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MLFELBAE_01678 5.24e-231 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
MLFELBAE_01679 1.04e-258 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MLFELBAE_01680 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
MLFELBAE_01681 1.79e-116 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
MLFELBAE_01682 9.36e-310 yhfA - - C - - - membrane
MLFELBAE_01683 3.08e-286 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
MLFELBAE_01684 1.43e-160 ecsC - - S - - - EcsC protein family
MLFELBAE_01685 2.24e-281 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
MLFELBAE_01686 1.82e-174 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
MLFELBAE_01687 5.82e-105 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
MLFELBAE_01688 3.28e-256 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MLFELBAE_01689 1.43e-100 trpP - - S - - - Tryptophan transporter TrpP
MLFELBAE_01690 2.55e-24 - - - - - - - -
MLFELBAE_01691 2.74e-54 yhaH - - S - - - YtxH-like protein
MLFELBAE_01692 8.17e-147 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
MLFELBAE_01693 1.2e-72 yhaI - - S - - - Protein of unknown function (DUF1878)
MLFELBAE_01694 1.29e-123 yhaK - - S - - - Putative zincin peptidase
MLFELBAE_01695 8.84e-184 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MLFELBAE_01696 1.23e-69 tnrA - - K - - - transcriptional
MLFELBAE_01697 1.11e-23 - - - - - - - -
MLFELBAE_01698 5.25e-37 ykoL - - - - - - -
MLFELBAE_01699 1.98e-105 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
MLFELBAE_01700 3.81e-129 ykoP - - G - - - polysaccharide deacetylase
MLFELBAE_01701 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
MLFELBAE_01702 2.47e-195 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MLFELBAE_01703 1.43e-131 ykoX - - S - - - membrane-associated protein
MLFELBAE_01704 6.84e-172 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
MLFELBAE_01705 6.02e-163 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLFELBAE_01706 1.84e-236 ykrI - - S - - - Anti-sigma factor N-terminus
MLFELBAE_01707 5.7e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
MLFELBAE_01708 1.55e-159 ykrK - - S - - - Domain of unknown function (DUF1836)
MLFELBAE_01709 6.35e-200 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
MLFELBAE_01710 3.64e-306 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
MLFELBAE_01711 6.05e-148 - - - S - - - Protein of unknown function (DUF421)
MLFELBAE_01712 3.07e-32 ykzE - - - - - - -
MLFELBAE_01713 5.54e-243 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
MLFELBAE_01714 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MLFELBAE_01715 2.55e-111 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MLFELBAE_01717 4.44e-251 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MLFELBAE_01718 6e-288 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
MLFELBAE_01719 6.67e-192 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MLFELBAE_01720 6.29e-292 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MLFELBAE_01721 2.73e-289 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
MLFELBAE_01722 2.71e-174 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
MLFELBAE_01723 3.87e-148 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
MLFELBAE_01724 2.6e-124 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
MLFELBAE_01726 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
MLFELBAE_01727 1.36e-100 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
MLFELBAE_01728 4.04e-169 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
MLFELBAE_01729 1.17e-176 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
MLFELBAE_01730 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
MLFELBAE_01731 6.6e-233 ykvI - - S - - - membrane
MLFELBAE_01732 1.27e-251 - - - - - - - -
MLFELBAE_01733 2.72e-162 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MLFELBAE_01734 1.26e-102 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
MLFELBAE_01735 2.06e-178 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
MLFELBAE_01736 2.56e-124 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MLFELBAE_01738 1e-79 - - - K - - - HxlR-like helix-turn-helix
MLFELBAE_01739 1.74e-168 ykvO - - IQ - - - Enoyl-(Acyl carrier protein) reductase
MLFELBAE_01740 2.64e-35 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MLFELBAE_01741 2.88e-270 - - - M - - - Glycosyl transferases group 1
MLFELBAE_01742 3.08e-47 - 3.5.1.104 - M ko:K22278 - ko00000,ko01000 LysM domain
MLFELBAE_01743 2.48e-204 - - - G - - - Glycosyl hydrolases family 18
MLFELBAE_01745 1.47e-59 ykvR - - S - - - Protein of unknown function (DUF3219)
MLFELBAE_01746 5.43e-35 ykvS - - S - - - protein conserved in bacteria
MLFELBAE_01747 4.16e-38 - - - - - - - -
MLFELBAE_01748 1.45e-142 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
MLFELBAE_01749 2.66e-306 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MLFELBAE_01750 2.1e-114 stoA - - CO - - - thiol-disulfide
MLFELBAE_01751 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
MLFELBAE_01752 1.41e-264 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
MLFELBAE_01754 1.01e-224 ykvZ - - K - - - Transcriptional regulator
MLFELBAE_01755 2.78e-199 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
MLFELBAE_01756 0.0 ptsG 2.7.1.199 - G ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MLFELBAE_01757 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
MLFELBAE_01758 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MLFELBAE_01759 3.63e-50 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
MLFELBAE_01760 1.44e-255 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
MLFELBAE_01761 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
MLFELBAE_01762 3.3e-202 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
MLFELBAE_01763 6.19e-170 ykwD - - J - - - protein with SCP PR1 domains
MLFELBAE_01764 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
MLFELBAE_01765 2.83e-300 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 PAS fold
MLFELBAE_01766 1.39e-98 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MLFELBAE_01767 4.65e-275 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MLFELBAE_01769 4.75e-214 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
MLFELBAE_01770 5.07e-108 ykyB - - S - - - YkyB-like protein
MLFELBAE_01771 2.28e-308 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
MLFELBAE_01772 5.14e-116 ykuD - - S - - - protein conserved in bacteria
MLFELBAE_01773 4.7e-198 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
MLFELBAE_01774 2.49e-180 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLFELBAE_01776 7.72e-297 ykuI - - T - - - Diguanylate phosphodiesterase
MLFELBAE_01777 3.63e-50 ykuJ - - S - - - protein conserved in bacteria
MLFELBAE_01778 4.35e-120 ykuK - - S ko:K09776 - ko00000 Ribonuclease H-like
MLFELBAE_01779 3.09e-35 ykzF - - S - - - Antirepressor AbbA
MLFELBAE_01780 8.55e-99 ykuL - - S - - - CBS domain
MLFELBAE_01781 1.32e-215 ccpC - - K - - - Transcriptional regulator
MLFELBAE_01782 1.28e-116 ykuN - - C ko:K03839 - ko00000 Flavodoxin
MLFELBAE_01783 4.41e-216 ykuO - - - - - - -
MLFELBAE_01784 2.52e-102 fld - - C ko:K03839 - ko00000 Flavodoxin
MLFELBAE_01785 2.89e-129 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MLFELBAE_01786 2.39e-277 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MLFELBAE_01787 2.15e-52 ykuS - - S - - - Belongs to the UPF0180 family
MLFELBAE_01788 6.03e-179 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
MLFELBAE_01789 2.24e-101 ykuV - - CO - - - thiol-disulfide
MLFELBAE_01790 3.04e-126 rok - - K - - - Repressor of ComK
MLFELBAE_01791 3.59e-218 yknT - - - ko:K06437 - ko00000 -
MLFELBAE_01792 9.54e-140 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
MLFELBAE_01793 2.33e-239 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MLFELBAE_01794 2.78e-309 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
MLFELBAE_01795 3.21e-122 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
MLFELBAE_01796 4.15e-108 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
MLFELBAE_01797 2.06e-46 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MLFELBAE_01798 3.81e-139 yknW - - S - - - Yip1 domain
MLFELBAE_01799 2e-246 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MLFELBAE_01800 2.9e-158 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MLFELBAE_01801 1.09e-271 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
MLFELBAE_01802 2.77e-171 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
MLFELBAE_01803 4.75e-214 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
MLFELBAE_01804 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
MLFELBAE_01805 5.36e-138 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MLFELBAE_01806 1.82e-50 ykoA - - - - - - -
MLFELBAE_01807 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MLFELBAE_01808 6.98e-211 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MLFELBAE_01809 1.2e-302 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
MLFELBAE_01810 4.47e-18 - - - S - - - Uncharacterized protein YkpC
MLFELBAE_01811 3.72e-235 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
MLFELBAE_01812 6.37e-60 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
MLFELBAE_01813 5.87e-313 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
MLFELBAE_01814 5.27e-197 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
MLFELBAE_01815 9.71e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
MLFELBAE_01816 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MLFELBAE_01817 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MLFELBAE_01818 4.45e-42 ykzG - - S - - - Belongs to the UPF0356 family
MLFELBAE_01819 3.17e-189 ykrA - - S - - - hydrolases of the HAD superfamily
MLFELBAE_01820 1.14e-130 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MLFELBAE_01821 1.08e-06 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
MLFELBAE_01822 5.6e-134 ykyA - - L - - - Putative cell-wall binding lipoprotein
MLFELBAE_01823 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
MLFELBAE_01824 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
MLFELBAE_01825 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 polyketide synthase
MLFELBAE_01826 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
MLFELBAE_01827 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
MLFELBAE_01828 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
MLFELBAE_01829 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
MLFELBAE_01830 0.0 - - - IQ - - - Phosphopantetheine attachment site
MLFELBAE_01831 3.48e-269 - - - V - - - Beta-lactamase
MLFELBAE_01832 7.79e-261 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MLFELBAE_01833 1.01e-226 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MLFELBAE_01834 2.96e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MLFELBAE_01835 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MLFELBAE_01836 7.97e-59 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
MLFELBAE_01837 7.14e-186 pdaA_2 3.5.1.104 - G ko:K01567,ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
MLFELBAE_01838 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
MLFELBAE_01839 9.4e-57 yktA - - S - - - Belongs to the UPF0223 family
MLFELBAE_01840 4.72e-154 yktB - - S - - - Belongs to the UPF0637 family
MLFELBAE_01841 7.89e-32 ykzI - - - - - - -
MLFELBAE_01842 8.12e-196 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
MLFELBAE_01843 1.3e-108 ykzC - - S - - - Acetyltransferase (GNAT) family
MLFELBAE_01844 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
MLFELBAE_01845 4.16e-236 ylaA - - - - - - -
MLFELBAE_01846 7.37e-59 ylaB - - - - - - -
MLFELBAE_01847 4.7e-120 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MLFELBAE_01849 6.54e-61 ylaE - - - - - - -
MLFELBAE_01850 5.62e-33 - - - S - - - Family of unknown function (DUF5325)
MLFELBAE_01851 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
MLFELBAE_01852 6.99e-65 - - - S - - - YlaH-like protein
MLFELBAE_01853 6.78e-46 ylaI - - S - - - protein conserved in bacteria
MLFELBAE_01854 3.84e-138 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MLFELBAE_01855 9.42e-314 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
MLFELBAE_01856 3.53e-110 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MLFELBAE_01857 2.67e-223 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
MLFELBAE_01858 1.99e-58 ylaN - - S - - - Belongs to the UPF0358 family
MLFELBAE_01859 1.42e-270 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
MLFELBAE_01860 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MLFELBAE_01861 3.47e-214 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
MLFELBAE_01862 2.07e-209 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MLFELBAE_01863 3.38e-252 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
MLFELBAE_01864 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MLFELBAE_01865 5.92e-142 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
MLFELBAE_01866 3.53e-69 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
MLFELBAE_01867 2.08e-211 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
MLFELBAE_01868 4.12e-79 ylbA - - S - - - YugN-like family
MLFELBAE_01869 1.36e-95 ylbB - - T - - - COG0517 FOG CBS domain
MLFELBAE_01870 2.8e-255 ylbC - - S - - - protein with SCP PR1 domains
MLFELBAE_01871 1.03e-87 ylbD - - S - - - Putative coat protein
MLFELBAE_01872 1.73e-48 ylbE - - S - - - YlbE-like protein
MLFELBAE_01873 3.33e-97 ylbF - - S - - - Belongs to the UPF0342 family
MLFELBAE_01874 2.78e-57 ylbG - - S - - - UPF0298 protein
MLFELBAE_01875 7.68e-116 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
MLFELBAE_01876 1.01e-110 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MLFELBAE_01877 8.35e-277 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
MLFELBAE_01878 1.23e-178 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
MLFELBAE_01879 5.09e-239 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
MLFELBAE_01880 5.01e-293 ylbM - - S - - - Belongs to the UPF0348 family
MLFELBAE_01881 4.88e-117 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
MLFELBAE_01882 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
MLFELBAE_01883 1.81e-110 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
MLFELBAE_01884 1.14e-116 ylbP - - K - - - n-acetyltransferase
MLFELBAE_01885 2.39e-210 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MLFELBAE_01886 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
MLFELBAE_01887 1.78e-101 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
MLFELBAE_01888 4.08e-219 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MLFELBAE_01889 2.4e-68 ftsL - - D - - - Essential cell division protein
MLFELBAE_01890 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
MLFELBAE_01891 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
MLFELBAE_01892 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MLFELBAE_01893 7.04e-222 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MLFELBAE_01894 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MLFELBAE_01895 2.7e-236 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
MLFELBAE_01896 5.45e-257 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MLFELBAE_01897 9.58e-214 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
MLFELBAE_01898 2.2e-178 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MLFELBAE_01899 1.57e-298 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MLFELBAE_01900 2.61e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MLFELBAE_01901 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
MLFELBAE_01902 1.94e-216 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
MLFELBAE_01903 7.35e-161 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLFELBAE_01904 9.33e-179 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLFELBAE_01905 1.62e-186 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
MLFELBAE_01906 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
MLFELBAE_01907 4.13e-51 ylmC - - S - - - sporulation protein
MLFELBAE_01908 9.55e-206 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
MLFELBAE_01909 2.59e-161 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MLFELBAE_01910 1.54e-83 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MLFELBAE_01911 5.12e-56 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
MLFELBAE_01912 3.54e-181 ylmH - - S - - - conserved protein, contains S4-like domain
MLFELBAE_01913 1.85e-99 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
MLFELBAE_01914 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MLFELBAE_01915 1.79e-84 ylyA - - T - - - COG1734 DnaK suppressor protein
MLFELBAE_01916 1.24e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MLFELBAE_01917 5.35e-216 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MLFELBAE_01918 2.21e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MLFELBAE_01919 1.39e-296 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
MLFELBAE_01920 2.44e-212 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
MLFELBAE_01921 3.79e-315 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MLFELBAE_01922 8.86e-268 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
MLFELBAE_01923 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
MLFELBAE_01924 5.24e-183 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
MLFELBAE_01925 7.36e-222 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MLFELBAE_01926 5.2e-163 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MLFELBAE_01927 7.37e-148 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MLFELBAE_01929 9.88e-181 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
MLFELBAE_01930 8.54e-229 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
MLFELBAE_01931 3.72e-285 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
MLFELBAE_01932 6.76e-143 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
MLFELBAE_01933 5.9e-185 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
MLFELBAE_01934 7.18e-188 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
MLFELBAE_01935 9.98e-103 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
MLFELBAE_01936 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MLFELBAE_01937 1.18e-67 licA 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MLFELBAE_01938 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MLFELBAE_01939 4.46e-66 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
MLFELBAE_01940 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
MLFELBAE_01941 2.98e-141 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
MLFELBAE_01942 1.57e-218 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLFELBAE_01943 4.83e-231 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLFELBAE_01944 9.23e-214 cbrA3 - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
MLFELBAE_01945 4.51e-77 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
MLFELBAE_01946 1.04e-289 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MLFELBAE_01947 1.18e-66 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MLFELBAE_01948 7.89e-66 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MLFELBAE_01949 6.01e-304 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MLFELBAE_01950 0.0 ydhP 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MLFELBAE_01951 2.18e-214 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
MLFELBAE_01952 1.11e-238 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
MLFELBAE_01953 1.31e-267 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
MLFELBAE_01954 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
MLFELBAE_01955 9.22e-245 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
MLFELBAE_01956 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
MLFELBAE_01957 1.07e-201 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MLFELBAE_01958 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
MLFELBAE_01959 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
MLFELBAE_01960 2.16e-239 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
MLFELBAE_01961 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
MLFELBAE_01962 1.51e-285 cimH - - C - - - COG3493 Na citrate symporter
MLFELBAE_01963 5.7e-199 yxkH - - G - - - Polysaccharide deacetylase
MLFELBAE_01964 5.06e-259 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MLFELBAE_01965 7.01e-213 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
MLFELBAE_01966 4.82e-190 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
MLFELBAE_01967 8.94e-119 yxkC - - S - - - Domain of unknown function (DUF4352)
MLFELBAE_01968 6.54e-250 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
MLFELBAE_01969 2.82e-301 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
MLFELBAE_01972 6.11e-111 yxjI - - S - - - LURP-one-related
MLFELBAE_01973 2.8e-278 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
MLFELBAE_01974 7.52e-206 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
MLFELBAE_01975 3.47e-268 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MLFELBAE_01976 3.75e-126 - - - T - - - Domain of unknown function (DUF4163)
MLFELBAE_01977 2.68e-67 yxiS - - - - - - -
MLFELBAE_01978 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
MLFELBAE_01979 1.57e-281 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
MLFELBAE_01980 2.33e-184 bglS - - M - - - licheninase activity
MLFELBAE_01981 1.39e-192 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
MLFELBAE_01982 1.05e-281 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
MLFELBAE_01983 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
MLFELBAE_01986 1.67e-79 - - - S - - - SMI1-KNR4 cell-wall
MLFELBAE_01987 5.7e-63 yxiI - - S - - - Protein of unknown function (DUF2716)
MLFELBAE_01988 2.38e-27 - - - - - - - -
MLFELBAE_01989 9.08e-12 yxiJ - - S - - - YxiJ-like protein
MLFELBAE_01993 6.87e-69 yxiG - - - - - - -
MLFELBAE_01994 9.53e-93 yxxG - - - - - - -
MLFELBAE_01997 1.56e-256 pelB 4.2.2.10, 4.2.2.2 - G ko:K01728,ko:K01732 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
MLFELBAE_01998 8.44e-208 yxxF - - EG - - - EamA-like transporter family
MLFELBAE_01999 1.44e-85 yxiE - - T - - - Belongs to the universal stress protein A family
MLFELBAE_02002 1.79e-70 - - - K - - - Transcriptional regulator
MLFELBAE_02003 6.08e-11 - - - K - - - Transcriptional regulator
MLFELBAE_02005 1.17e-39 - - - - - - - -
MLFELBAE_02006 3.12e-26 - - - L - - - Replication protein
MLFELBAE_02007 2.6e-75 - - - L - - - Replication protein
MLFELBAE_02008 3.73e-18 - - - S - - - Domain of unknown function (DUF5082)
MLFELBAE_02009 4.8e-59 - - - L ko:K07458 - ko00000,ko01000,ko03400 May nick specific sequences that contain T G mispairs resulting from m5C-deamination
MLFELBAE_02010 3.9e-232 dcm 2.1.1.37 - H ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 C-5 cytosine-specific DNA methylase
MLFELBAE_02011 4.28e-115 - - - S - - - GTP binding
MLFELBAE_02012 2.43e-87 - - - L - - - NgoFVII restriction endonuclease
MLFELBAE_02013 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
MLFELBAE_02014 9.97e-103 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
MLFELBAE_02015 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
MLFELBAE_02016 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MLFELBAE_02017 2.61e-298 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
MLFELBAE_02018 5.85e-226 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
MLFELBAE_02019 0.0 hutM - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
MLFELBAE_02020 3.85e-297 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
MLFELBAE_02021 4.04e-265 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MLFELBAE_02022 4.09e-145 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MLFELBAE_02023 1e-220 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MLFELBAE_02024 1.34e-192 yxeH - - S - - - hydrolases of the HAD superfamily
MLFELBAE_02027 2.06e-42 yxeE - - - - - - -
MLFELBAE_02028 5.09e-35 yxeD - - - - - - -
MLFELBAE_02030 8.33e-228 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
MLFELBAE_02031 9.89e-76 yxeA - - S - - - Protein of unknown function (DUF1093)
MLFELBAE_02032 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
MLFELBAE_02033 3.28e-182 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MLFELBAE_02034 3.23e-223 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MLFELBAE_02035 5.65e-160 yxdJ - - T ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLFELBAE_02036 0.0 - - - T - - - Histidine kinase
MLFELBAE_02037 1.57e-176 yvrH - - T - - - Transcriptional regulator
MLFELBAE_02038 5.31e-211 - - - V ko:K20459,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MLFELBAE_02039 1.36e-167 - - - S ko:K20460 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 permease
MLFELBAE_02040 1.89e-170 - - - S ko:K20461 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
MLFELBAE_02041 8.12e-204 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
MLFELBAE_02042 1.03e-201 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
MLFELBAE_02043 1.08e-212 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
MLFELBAE_02044 5.4e-252 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
MLFELBAE_02045 5.22e-294 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
MLFELBAE_02046 3.96e-224 iolE 4.2.1.44 - H ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
MLFELBAE_02047 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
MLFELBAE_02048 2.4e-232 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
MLFELBAE_02049 6.21e-203 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
MLFELBAE_02050 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MLFELBAE_02051 6.09e-175 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
MLFELBAE_02052 1.43e-223 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
MLFELBAE_02053 1.1e-313 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MLFELBAE_02054 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
MLFELBAE_02056 8.74e-195 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
MLFELBAE_02057 1.07e-131 desR - - T ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLFELBAE_02058 2.38e-254 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MLFELBAE_02059 1.23e-255 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
MLFELBAE_02060 1.98e-274 yxbF - - K - - - Bacterial regulatory proteins, tetR family
MLFELBAE_02061 0.0 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
MLFELBAE_02062 2.33e-187 yxaL - - S - - - PQQ-like domain
MLFELBAE_02063 8.36e-84 - - - S - - - Family of unknown function (DUF5391)
MLFELBAE_02064 7.01e-67 arsR3 - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MLFELBAE_02065 1.97e-258 - - - EGP - - - Major Facilitator Superfamily
MLFELBAE_02066 1.92e-97 yxaI - - S - - - membrane protein domain
MLFELBAE_02067 1.34e-162 - - - E - - - Ring-cleavage extradiol dioxygenase
MLFELBAE_02068 1.61e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
MLFELBAE_02069 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
MLFELBAE_02070 7.64e-290 - - - S - - - Fic/DOC family
MLFELBAE_02071 5.26e-314 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
MLFELBAE_02072 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
MLFELBAE_02073 3.87e-111 pucE 1.2.5.3 - C ko:K03518 - ko00000,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
MLFELBAE_02074 1.63e-198 - - - C - - - COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
MLFELBAE_02075 0.0 - - - C - - - COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
MLFELBAE_02076 2.63e-119 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
MLFELBAE_02077 1.52e-239 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MLFELBAE_02078 2.71e-235 - - - S - - - Fusaric acid resistance protein-like
MLFELBAE_02079 2.06e-25 - - - - - - - -
MLFELBAE_02080 5.82e-20 - - - K - - - Helix-turn-helix XRE-family like proteins
MLFELBAE_02081 1.09e-138 yhdJ 2.1.1.72 - L ko:K00571,ko:K07319 - ko00000,ko01000,ko02048 Belongs to the N(4) N(6)-methyltransferase family
MLFELBAE_02084 4.5e-100 - - - S - - - AIPR protein
MLFELBAE_02085 1.01e-105 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MLFELBAE_02089 1.45e-275 yycP - - - - - - -
MLFELBAE_02090 1.43e-172 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MLFELBAE_02091 3.17e-235 - - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
MLFELBAE_02092 3.54e-114 yycN - - K - - - Acetyltransferase
MLFELBAE_02094 3.17e-260 - - - S ko:K06361,ko:K06365,ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
MLFELBAE_02095 1.86e-212 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
MLFELBAE_02096 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
MLFELBAE_02097 9.68e-295 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
MLFELBAE_02098 2.68e-87 yvaZ - - S - - - Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
MLFELBAE_02099 2.69e-57 sdpR - - K - - - transcriptional
MLFELBAE_02100 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
MLFELBAE_02101 2.16e-187 - 1.14.11.27 - P ko:K10277 - ko00000,ko01000,ko03036 peptidyl-arginine hydroxylation
MLFELBAE_02102 0.0 - - - S - - - ABC transporter
MLFELBAE_02103 1.85e-252 - - - S - - - Major Facilitator Superfamily
MLFELBAE_02104 0.0 - - - - - - - -
MLFELBAE_02105 2.93e-244 thiF 2.7.7.73 - H ko:K03148 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 ThiF family
MLFELBAE_02106 0.0 - 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
MLFELBAE_02107 9.23e-14 phoP1 - - KT ko:K02483 - ko00000,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLFELBAE_02108 1.63e-278 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MLFELBAE_02109 9.84e-192 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
MLFELBAE_02110 1.19e-195 yycI - - S - - - protein conserved in bacteria
MLFELBAE_02111 0.0 yycH - - S - - - protein conserved in bacteria
MLFELBAE_02112 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MLFELBAE_02113 1.51e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLFELBAE_02118 1.06e-315 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MLFELBAE_02119 1.63e-96 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MLFELBAE_02120 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
MLFELBAE_02121 2.21e-38 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
MLFELBAE_02123 7.28e-25 yycC - - K - - - YycC-like protein
MLFELBAE_02124 1.92e-51 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase activity
MLFELBAE_02125 8.52e-304 - - - M - - - Glycosyltransferase Family 4
MLFELBAE_02126 9.45e-261 - - - S - - - Ecdysteroid kinase
MLFELBAE_02127 4.63e-297 - - - S - - - Carbamoyl-phosphate synthase L chain, ATP binding domain
MLFELBAE_02128 1.35e-298 - - - M - - - Glycosyltransferase Family 4
MLFELBAE_02129 1.25e-156 - - - S - - - GlcNAc-PI de-N-acetylase
MLFELBAE_02130 8.06e-156 - - - KLT - - - COG0515 Serine threonine protein kinase
MLFELBAE_02131 1.58e-95 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
MLFELBAE_02132 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
MLFELBAE_02133 5.01e-204 yybS - - S - - - membrane
MLFELBAE_02135 3.33e-111 cotF - - M ko:K06329 - ko00000 Spore coat protein
MLFELBAE_02136 4.56e-87 yybR - - K - - - Transcriptional regulator
MLFELBAE_02137 2.95e-211 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
MLFELBAE_02138 8.34e-197 ypaH - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MLFELBAE_02139 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
MLFELBAE_02140 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
MLFELBAE_02141 3.98e-151 - - - K - - - FCD domain
MLFELBAE_02142 1.36e-117 - - - S - - - PFAM DinB family protein
MLFELBAE_02143 2.34e-204 - - - G - - - Major Facilitator Superfamily
MLFELBAE_02144 3.56e-203 - - - K - - - LysR substrate binding domain
MLFELBAE_02145 9.29e-129 - - - E - - - LysE type translocator
MLFELBAE_02146 1.94e-74 ypaA - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
MLFELBAE_02147 1.7e-148 ydgI - - C - - - nitroreductase
MLFELBAE_02148 1.37e-89 - - - K - - - Winged helix DNA-binding domain
MLFELBAE_02149 1.38e-196 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
MLFELBAE_02150 1.3e-99 yybA - - K - - - transcriptional
MLFELBAE_02151 4.45e-99 yjcF - - S - - - Acetyltransferase (GNAT) domain
MLFELBAE_02152 9.58e-211 - - - M - - - Domain of Unknown Function (DUF1259)
MLFELBAE_02153 2.02e-88 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
MLFELBAE_02154 4.21e-212 - - - K - - - Transcriptional regulator
MLFELBAE_02155 1.27e-180 bdh 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
MLFELBAE_02156 4.3e-312 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MLFELBAE_02157 4.96e-164 - - - EG - - - EamA-like transporter family
MLFELBAE_02158 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
MLFELBAE_02159 3.6e-211 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
MLFELBAE_02160 0.0 - - - G ko:K08369 - ko00000,ko02000 Sugar (and other) transporter
MLFELBAE_02161 1.99e-87 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MLFELBAE_02162 1.19e-232 ccpB - - K - - - Transcriptional regulator
MLFELBAE_02163 1.98e-185 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
MLFELBAE_02164 2.04e-129 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MLFELBAE_02165 1.26e-136 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
MLFELBAE_02166 1.11e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MLFELBAE_02167 4.77e-99 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MLFELBAE_02168 2.9e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
MLFELBAE_02169 5.42e-254 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MLFELBAE_02170 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MLFELBAE_02171 1.82e-45 yyzM - - S - - - protein conserved in bacteria
MLFELBAE_02172 3.36e-225 yyaD - - S - - - Membrane
MLFELBAE_02173 4.04e-109 yhhY - - K - - - FR47-like protein
MLFELBAE_02174 4.91e-144 yyaC - - S - - - Sporulation protein YyaC
MLFELBAE_02175 8.27e-189 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
MLFELBAE_02176 1.18e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
MLFELBAE_02177 6.61e-195 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
MLFELBAE_02178 2.29e-164 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
MLFELBAE_02179 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MLFELBAE_02180 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MLFELBAE_02181 6.6e-142 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
MLFELBAE_02182 2.12e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MLFELBAE_02183 1.99e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MLFELBAE_02184 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MLFELBAE_02185 3.45e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MLFELBAE_02186 3.19e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
MLFELBAE_02187 3.2e-264 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MLFELBAE_02188 6.18e-52 yaaB - - S - - - Domain of unknown function (DUF370)
MLFELBAE_02189 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MLFELBAE_02190 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MLFELBAE_02212 2.59e-102 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
MLFELBAE_02213 6.11e-169 yteA - - T - - - COG1734 DnaK suppressor protein
MLFELBAE_02214 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
MLFELBAE_02215 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MLFELBAE_02216 8.79e-200 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
MLFELBAE_02217 7.52e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MLFELBAE_02218 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MLFELBAE_02219 1e-272 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
MLFELBAE_02220 1.92e-34 - - - S - - - Domain of Unknown Function (DUF1540)
MLFELBAE_02221 2.49e-233 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
MLFELBAE_02222 2.59e-312 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
MLFELBAE_02223 8.35e-55 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
MLFELBAE_02224 9.31e-137 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
MLFELBAE_02225 6.93e-53 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
MLFELBAE_02226 7.16e-114 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MLFELBAE_02227 1.04e-99 ytkA - - S - - - YtkA-like
MLFELBAE_02229 1.8e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
MLFELBAE_02230 1.23e-79 ytkC - - S - - - Bacteriophage holin family
MLFELBAE_02231 1.01e-114 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
MLFELBAE_02232 2.16e-173 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MLFELBAE_02233 6.12e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MLFELBAE_02234 9.14e-239 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
MLFELBAE_02235 7.79e-190 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
MLFELBAE_02236 2.85e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
MLFELBAE_02237 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MLFELBAE_02238 7.88e-287 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MLFELBAE_02239 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
MLFELBAE_02240 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
MLFELBAE_02241 4.06e-84 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MLFELBAE_02242 5.71e-193 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
MLFELBAE_02243 2.35e-270 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
MLFELBAE_02244 9e-186 - 3.1.4.46, 5.4.2.11 - C ko:K01126,ko:K01834 ko00010,ko00260,ko00564,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00564,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 glycerophosphoryl diester phosphodiesterase
MLFELBAE_02246 3.1e-137 ytqB - - J - - - Putative rRNA methylase
MLFELBAE_02247 5.76e-245 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
MLFELBAE_02248 0.0 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
MLFELBAE_02249 1.13e-249 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MLFELBAE_02250 7.09e-53 ytzC - - S - - - Protein of unknown function (DUF2524)
MLFELBAE_02252 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
MLFELBAE_02253 4.38e-209 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MLFELBAE_02254 5.02e-212 ytrC - - S ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
MLFELBAE_02255 5.41e-228 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
MLFELBAE_02256 1.56e-210 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
MLFELBAE_02257 2.12e-161 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MLFELBAE_02258 3.9e-287 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
MLFELBAE_02259 4.49e-167 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLFELBAE_02260 1.18e-219 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
MLFELBAE_02261 3.81e-173 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
MLFELBAE_02262 0.0 bceB - - V ko:K02004,ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
MLFELBAE_02263 1.92e-153 ywaF - - S - - - Integral membrane protein
MLFELBAE_02264 1.36e-268 yttB - - EGP - - - Major facilitator superfamily
MLFELBAE_02265 1.77e-176 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
MLFELBAE_02266 7.19e-69 ytvB - - S - - - Protein of unknown function (DUF4257)
MLFELBAE_02267 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
MLFELBAE_02268 2.47e-68 ytwF - - P - - - Sulfurtransferase
MLFELBAE_02269 5.91e-112 - - - M - - - Acetyltransferase (GNAT) domain
MLFELBAE_02270 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
MLFELBAE_02271 2.37e-183 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
MLFELBAE_02272 1.6e-217 - - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MLFELBAE_02273 2.28e-310 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
MLFELBAE_02274 3.87e-239 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
MLFELBAE_02275 2.14e-36 yteV - - S - - - Sporulation protein Cse60
MLFELBAE_02276 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
MLFELBAE_02277 3.73e-299 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
MLFELBAE_02278 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MLFELBAE_02279 8.68e-169 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MLFELBAE_02280 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
MLFELBAE_02281 2.58e-163 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MLFELBAE_02282 9.06e-279 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
MLFELBAE_02283 2.99e-290 pbuO - - S ko:K06901 - ko00000,ko02000 permease
MLFELBAE_02284 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
MLFELBAE_02285 2.38e-222 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
MLFELBAE_02286 3.14e-132 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MLFELBAE_02287 9.95e-215 ytlQ - - - - - - -
MLFELBAE_02288 8.33e-227 ytlR - - I - - - Diacylglycerol kinase catalytic domain
MLFELBAE_02289 2.93e-199 ytmP - - M - - - Phosphotransferase
MLFELBAE_02290 3.88e-60 ytzH - - S - - - YtzH-like protein
MLFELBAE_02291 6.43e-160 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MLFELBAE_02292 6.76e-212 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
MLFELBAE_02293 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
MLFELBAE_02294 9.96e-69 ytzB - - S - - - small secreted protein
MLFELBAE_02295 4.33e-260 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
MLFELBAE_02296 1.42e-102 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
MLFELBAE_02297 5.47e-76 ytpP - - CO - - - Thioredoxin
MLFELBAE_02298 8.04e-189 ytpQ - - S - - - Belongs to the UPF0354 family
MLFELBAE_02299 5.96e-139 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MLFELBAE_02300 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
MLFELBAE_02301 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
MLFELBAE_02302 5.38e-26 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MLFELBAE_02303 1.83e-30 ytxH - - S - - - COG4980 Gas vesicle protein
MLFELBAE_02304 8.39e-58 ytxJ - - O - - - Protein of unknown function (DUF2847)
MLFELBAE_02305 1.54e-249 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
MLFELBAE_02306 5.91e-235 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
MLFELBAE_02307 1.23e-184 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
MLFELBAE_02308 1.05e-155 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
MLFELBAE_02309 3.91e-290 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
MLFELBAE_02310 1.02e-150 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
MLFELBAE_02311 1.71e-156 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
MLFELBAE_02312 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MLFELBAE_02313 2.44e-303 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MLFELBAE_02314 2.52e-63 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
MLFELBAE_02315 5.77e-160 ygaZ - - E - - - AzlC protein
MLFELBAE_02316 7.76e-191 - - - K - - - Transcriptional regulator
MLFELBAE_02317 4.99e-193 - - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MLFELBAE_02318 1.68e-176 - - - E - - - GDSL-like Lipase/Acylhydrolase family
MLFELBAE_02320 1.65e-118 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
MLFELBAE_02322 9.15e-284 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MLFELBAE_02323 1.65e-76 yokH - - G - - - SMI1 / KNR4 family
MLFELBAE_02324 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
MLFELBAE_02325 5.75e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MLFELBAE_02326 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
MLFELBAE_02327 5.2e-113 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
MLFELBAE_02328 2.41e-141 yttP - - K - - - Transcriptional regulator
MLFELBAE_02329 1.46e-196 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
MLFELBAE_02330 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MLFELBAE_02331 1.96e-308 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
MLFELBAE_02332 5.54e-266 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
MLFELBAE_02333 2.09e-287 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MLFELBAE_02334 2.05e-42 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
MLFELBAE_02335 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MLFELBAE_02336 0.0 ytcJ - - S - - - amidohydrolase
MLFELBAE_02337 2.71e-195 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MLFELBAE_02338 3.7e-234 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
MLFELBAE_02339 2.77e-114 yteJ - - S - - - RDD family
MLFELBAE_02340 3.66e-156 ytfI - - S - - - Protein of unknown function (DUF2953)
MLFELBAE_02341 9.89e-84 ytfJ - - S - - - Sporulation protein YtfJ
MLFELBAE_02342 1.36e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MLFELBAE_02343 3.18e-236 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
MLFELBAE_02344 2.33e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MLFELBAE_02345 4.03e-115 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
MLFELBAE_02346 4.3e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
MLFELBAE_02347 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
MLFELBAE_02349 9.79e-183 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLFELBAE_02350 3.42e-165 ytkL - - S - - - Belongs to the UPF0173 family
MLFELBAE_02351 6.77e-305 ytoI - - K - - - transcriptional regulator containing CBS domains
MLFELBAE_02352 3.05e-63 ytpI - - S - - - YtpI-like protein
MLFELBAE_02353 2.14e-231 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
MLFELBAE_02354 1e-31 - - - - - - - -
MLFELBAE_02355 2.64e-114 ytrI - - - - - - -
MLFELBAE_02356 4.94e-75 ytrH - - S - - - Sporulation protein YtrH
MLFELBAE_02357 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
MLFELBAE_02358 1.72e-286 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
MLFELBAE_02359 3.59e-207 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MLFELBAE_02360 3.28e-232 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
MLFELBAE_02361 3.98e-230 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MLFELBAE_02362 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
MLFELBAE_02363 3.42e-84 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
MLFELBAE_02364 4.05e-247 ytvI - - S - - - sporulation integral membrane protein YtvI
MLFELBAE_02365 2.3e-95 ytwI - - S - - - membrane
MLFELBAE_02366 5.5e-83 yjdF3 - - S - - - Protein of unknown function (DUF2992)
MLFELBAE_02367 8.21e-268 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
MLFELBAE_02368 1.32e-308 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
MLFELBAE_02369 3.62e-218 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
MLFELBAE_02370 1.38e-165 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLFELBAE_02371 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
MLFELBAE_02372 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MLFELBAE_02373 9.87e-203 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MLFELBAE_02374 2e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
MLFELBAE_02375 2.94e-128 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MLFELBAE_02376 1.59e-205 ytbE - - S - - - reductase
MLFELBAE_02377 1.97e-259 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
MLFELBAE_02378 1.69e-89 ytcD - - K - - - Transcriptional regulator
MLFELBAE_02379 2.19e-249 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MLFELBAE_02380 1.82e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MLFELBAE_02381 5.95e-106 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MLFELBAE_02382 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
MLFELBAE_02383 3e-200 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
MLFELBAE_02384 7.7e-141 ytxB - - S - - - SNARE associated Golgi protein
MLFELBAE_02385 1.99e-197 ytxC - - S - - - YtxC-like family
MLFELBAE_02386 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MLFELBAE_02387 2.94e-193 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
MLFELBAE_02388 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MLFELBAE_02389 3e-167 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
MLFELBAE_02390 2.76e-69 - - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 effector of murein hydrolase LrgA
MLFELBAE_02391 3.1e-147 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
MLFELBAE_02392 1.79e-112 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MLFELBAE_02393 1.95e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
MLFELBAE_02394 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MLFELBAE_02395 7.74e-56 ysdA - - S - - - Membrane
MLFELBAE_02396 9.71e-90 ysdB - - S - - - Sigma-w pathway protein YsdB
MLFELBAE_02397 1.85e-263 ysdC - - G - - - COG1363 Cellulase M and related proteins
MLFELBAE_02398 6.97e-241 abnA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
MLFELBAE_02399 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
MLFELBAE_02400 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
MLFELBAE_02401 3.43e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
MLFELBAE_02402 1.77e-180 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
MLFELBAE_02403 1.35e-284 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
MLFELBAE_02404 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
MLFELBAE_02405 4.38e-215 araP - - P ko:K10189,ko:K10241,ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PFAM binding-protein-dependent transport systems inner membrane component
MLFELBAE_02406 4.82e-191 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
MLFELBAE_02407 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
MLFELBAE_02408 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
MLFELBAE_02409 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
MLFELBAE_02410 0.0 - 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD binding domain
MLFELBAE_02411 4.35e-262 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
MLFELBAE_02412 1.07e-43 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
MLFELBAE_02413 1.89e-172 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MLFELBAE_02414 2.19e-249 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MLFELBAE_02415 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MLFELBAE_02416 1.03e-213 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MLFELBAE_02417 1.47e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MLFELBAE_02418 3.5e-108 yshB - - S - - - membrane protein, required for colicin V production
MLFELBAE_02419 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
MLFELBAE_02420 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MLFELBAE_02421 3.09e-88 yshE - - S ko:K08989 - ko00000 membrane
MLFELBAE_02422 4.49e-159 ywbB - - S - - - Protein of unknown function (DUF2711)
MLFELBAE_02423 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MLFELBAE_02424 6.22e-134 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
MLFELBAE_02425 2.48e-178 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
MLFELBAE_02426 8.64e-178 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
MLFELBAE_02427 3.02e-228 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
MLFELBAE_02428 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
MLFELBAE_02429 1.6e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
MLFELBAE_02430 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MLFELBAE_02431 1.74e-274 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
MLFELBAE_02432 2.45e-103 yslB - - S - - - Protein of unknown function (DUF2507)
MLFELBAE_02433 2.73e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
MLFELBAE_02434 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
MLFELBAE_02435 4.34e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
MLFELBAE_02436 2.67e-101 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
MLFELBAE_02437 6.32e-42 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
MLFELBAE_02438 3.77e-97 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
MLFELBAE_02439 4.68e-196 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
MLFELBAE_02440 2.58e-254 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
MLFELBAE_02441 1.44e-170 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MLFELBAE_02442 1.59e-131 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MLFELBAE_02443 4.05e-119 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
MLFELBAE_02447 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
MLFELBAE_02448 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 Type I restriction-modification system
MLFELBAE_02449 1.09e-65 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
MLFELBAE_02450 5.59e-17 res - - L - - - Resolvase, N terminal domain
MLFELBAE_02451 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
MLFELBAE_02452 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
MLFELBAE_02453 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MLFELBAE_02454 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
MLFELBAE_02455 6.36e-130 yvgT - - S - - - membrane
MLFELBAE_02456 6.64e-191 - - - S - - - Metallo-peptidase family M12
MLFELBAE_02457 3.56e-94 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
MLFELBAE_02458 3.33e-140 bdbD - - O - - - Thioredoxin
MLFELBAE_02459 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
MLFELBAE_02460 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
MLFELBAE_02461 3.24e-40 - - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Heavy-metal-associated domain
MLFELBAE_02462 8.06e-64 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
MLFELBAE_02463 8.25e-248 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
MLFELBAE_02464 5.95e-153 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MLFELBAE_02465 4.21e-207 - - - K - - - Helix-turn-helix XRE-family like proteins
MLFELBAE_02466 6.18e-282 - - - EGP - - - Major Facilitator Superfamily
MLFELBAE_02467 2.61e-91 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
MLFELBAE_02468 1.19e-186 - - - S ko:K07045 - ko00000 Amidohydrolase
MLFELBAE_02469 0.0 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLFELBAE_02470 4.82e-60 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
MLFELBAE_02471 8.34e-231 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLFELBAE_02472 1.82e-180 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
MLFELBAE_02473 5.8e-156 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MLFELBAE_02474 1.79e-157 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MLFELBAE_02475 1.5e-189 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
MLFELBAE_02476 1.39e-166 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
MLFELBAE_02477 3.16e-130 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
MLFELBAE_02478 1.89e-204 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
MLFELBAE_02479 3.94e-180 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
MLFELBAE_02480 1.19e-65 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
MLFELBAE_02481 3.81e-52 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
MLFELBAE_02483 4.85e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MLFELBAE_02484 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MLFELBAE_02485 1.7e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
MLFELBAE_02486 4.58e-36 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
MLFELBAE_02487 1.64e-47 yvzC - - K - - - transcriptional
MLFELBAE_02488 9.53e-93 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
MLFELBAE_02489 3.52e-96 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
MLFELBAE_02490 2.97e-70 yvaP - - K - - - transcriptional
MLFELBAE_02491 0.0 spaK 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
MLFELBAE_02492 4.69e-159 spaR - - K ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
MLFELBAE_02493 6.3e-175 spaG - - S ko:K20492 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
MLFELBAE_02494 6.23e-160 spaE - - S ko:K20491 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
MLFELBAE_02495 5.4e-162 spaF - - V ko:K01990,ko:K20459,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MLFELBAE_02496 4.22e-144 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
MLFELBAE_02497 2.67e-221 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MLFELBAE_02498 8e-145 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
MLFELBAE_02499 5.78e-268 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MLFELBAE_02500 3.42e-124 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
MLFELBAE_02501 6.21e-141 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
MLFELBAE_02502 3.25e-222 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MLFELBAE_02503 1.61e-144 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
MLFELBAE_02504 2.98e-269 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MLFELBAE_02505 4.11e-129 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
MLFELBAE_02506 3.8e-135 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
MLFELBAE_02507 2.66e-157 yvbI - - M - - - Membrane
MLFELBAE_02508 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
MLFELBAE_02509 1.11e-106 yvbK - - K - - - acetyltransferase
MLFELBAE_02510 3.81e-270 - - - EGP - - - Major facilitator Superfamily
MLFELBAE_02511 6.59e-227 - - - - - - - -
MLFELBAE_02512 1.83e-161 - - - S - - - GlcNAc-PI de-N-acetylase
MLFELBAE_02513 1.67e-184 - - - C - - - WbqC-like protein family
MLFELBAE_02514 6.49e-191 - - - M - - - Protein involved in cellulose biosynthesis
MLFELBAE_02515 2.93e-298 - - - E - - - UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MLFELBAE_02516 1.22e-219 arnA 4.2.1.46, 5.1.3.2 - M ko:K01710,ko:K01784 ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130 ko00000,ko00001,ko00002,ko01000 GDP-mannose 4,6 dehydratase
MLFELBAE_02517 3.4e-278 - 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
MLFELBAE_02518 0.0 - 1.1.1.136 - M ko:K13015 ko00520,map00520 ko00000,ko00001,ko01000,ko01005 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MLFELBAE_02519 1.52e-306 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
MLFELBAE_02520 9.69e-310 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MLFELBAE_02521 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
MLFELBAE_02522 2.58e-177 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MLFELBAE_02523 3.98e-277 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
MLFELBAE_02524 4.7e-237 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MLFELBAE_02525 2.95e-240 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MLFELBAE_02527 0.0 araE - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MLFELBAE_02528 9.49e-262 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
MLFELBAE_02531 1.71e-241 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLFELBAE_02533 8.34e-198 yvbU - - K - - - Transcriptional regulator
MLFELBAE_02534 5.22e-203 yvbV - - EG - - - EamA-like transporter family
MLFELBAE_02535 4.71e-275 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
MLFELBAE_02536 0.0 - - - - - - - -
MLFELBAE_02537 3.55e-231 yhjM - - K - - - Transcriptional regulator
MLFELBAE_02538 8.98e-149 - - - S ko:K07149 - ko00000 Membrane
MLFELBAE_02539 4.41e-215 - 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
MLFELBAE_02540 1.56e-194 gntR - - K - - - RpiR family transcriptional regulator
MLFELBAE_02541 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
MLFELBAE_02542 1.37e-290 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
MLFELBAE_02543 4.13e-172 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MLFELBAE_02544 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
MLFELBAE_02545 2.14e-173 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MLFELBAE_02546 2.25e-284 - - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MLFELBAE_02547 3.1e-156 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
MLFELBAE_02548 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
MLFELBAE_02549 3.79e-308 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
MLFELBAE_02550 4.01e-44 yvfG - - S - - - YvfG protein
MLFELBAE_02551 2.84e-240 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
MLFELBAE_02552 9.49e-283 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
MLFELBAE_02553 5.73e-79 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
MLFELBAE_02554 1.92e-140 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MLFELBAE_02555 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MLFELBAE_02556 1.48e-249 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
MLFELBAE_02557 2.13e-256 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
MLFELBAE_02558 5.37e-248 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
MLFELBAE_02559 3.44e-262 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
MLFELBAE_02560 2.03e-271 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
MLFELBAE_02561 3.2e-205 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
MLFELBAE_02562 7.13e-277 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
MLFELBAE_02563 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
MLFELBAE_02564 7.67e-152 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
MLFELBAE_02565 4.08e-156 epsA - - M ko:K19420 - ko00000 biosynthesis protein
MLFELBAE_02566 6.96e-100 - - - K ko:K19417 - ko00000,ko03000 transcriptional
MLFELBAE_02567 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
MLFELBAE_02568 3.85e-125 ywjB - - H - - - RibD C-terminal domain
MLFELBAE_02569 2.51e-144 yyaS - - S ko:K07149 - ko00000 Membrane
MLFELBAE_02570 5.46e-119 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MLFELBAE_02571 2.47e-121 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
MLFELBAE_02572 6.65e-17 - - - S - - - Protein of unknown function (DUF1433)
MLFELBAE_02573 3.36e-62 - - - S - - - Protein of unknown function (DUF1433)
MLFELBAE_02574 7.71e-51 - - - IU - - - Lipase (class 3)
MLFELBAE_02575 5.79e-33 - - - S - - - Protein of unknown function (DUF1433)
MLFELBAE_02576 7.79e-36 - - - S - - - Protein of unknown function (DUF1433)
MLFELBAE_02577 3.28e-297 - - - I - - - Pfam Lipase (class 3)
MLFELBAE_02578 2.53e-43 - - - - - - - -
MLFELBAE_02580 0.0 cscA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
MLFELBAE_02581 1.65e-284 rafB - - P ko:K02532 - ko00000,ko02000 LacY proton/sugar symporter
MLFELBAE_02582 2.23e-234 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
MLFELBAE_02583 3.74e-136 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MLFELBAE_02584 3.34e-210 yraN - - K - - - Transcriptional regulator
MLFELBAE_02585 3.5e-271 yraM - - S - - - PrpF protein
MLFELBAE_02586 0.0 - - - EGP - - - Sugar (and other) transporter
MLFELBAE_02588 3.78e-137 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
MLFELBAE_02589 1.3e-69 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
MLFELBAE_02590 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
MLFELBAE_02591 4.41e-137 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
MLFELBAE_02592 6.9e-232 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MLFELBAE_02593 5.54e-105 - - - M - - - Ribonuclease
MLFELBAE_02594 6.92e-184 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
MLFELBAE_02595 2.76e-50 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
MLFELBAE_02596 1.48e-219 whiA - - K ko:K09762 - ko00000 May be required for sporulation
MLFELBAE_02597 3.66e-225 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
MLFELBAE_02598 2.09e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
MLFELBAE_02599 5.15e-113 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
MLFELBAE_02600 3.13e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MLFELBAE_02601 4.08e-201 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
MLFELBAE_02602 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
MLFELBAE_02603 3.35e-246 sasA - - T - - - Histidine kinase
MLFELBAE_02604 1.62e-157 mprA3 - - T - - - COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLFELBAE_02605 5.51e-73 - - - - - - - -
MLFELBAE_02606 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
MLFELBAE_02607 8.12e-144 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
MLFELBAE_02608 3.4e-177 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MLFELBAE_02609 9.3e-167 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MLFELBAE_02610 2.32e-146 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MLFELBAE_02611 1.17e-137 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
MLFELBAE_02612 2.72e-299 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MLFELBAE_02613 1.83e-148 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MLFELBAE_02614 6.03e-270 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MLFELBAE_02615 4.16e-177 yvpB - - NU - - - protein conserved in bacteria
MLFELBAE_02616 1.7e-112 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
MLFELBAE_02617 9.48e-157 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
MLFELBAE_02618 4.15e-192 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MLFELBAE_02619 6e-216 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MLFELBAE_02620 2.45e-288 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
MLFELBAE_02621 1.9e-173 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MLFELBAE_02622 1.05e-171 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
MLFELBAE_02623 1.27e-135 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
MLFELBAE_02624 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
MLFELBAE_02625 7.66e-66 yvlD - - S ko:K08972 - ko00000 Membrane
MLFELBAE_02626 4.01e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
MLFELBAE_02627 3.2e-218 yvlB - - S - - - Putative adhesin
MLFELBAE_02628 4.87e-66 yvlA - - - - - - -
MLFELBAE_02629 1.03e-50 yvkN - - - - - - -
MLFELBAE_02630 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MLFELBAE_02631 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MLFELBAE_02632 2.59e-45 csbA - - S - - - protein conserved in bacteria
MLFELBAE_02633 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
MLFELBAE_02634 2.32e-144 yvkB - - K - - - Transcriptional regulator
MLFELBAE_02635 5.92e-298 yvkA - - P - - - -transporter
MLFELBAE_02636 1.91e-232 - - - S - - - Psort location CytoplasmicMembrane, score
MLFELBAE_02637 8.77e-282 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MLFELBAE_02638 2.47e-73 swrA - - S - - - Swarming motility protein
MLFELBAE_02639 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
MLFELBAE_02640 7.31e-306 ywoF - - P - - - Right handed beta helix region
MLFELBAE_02641 2.48e-198 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
MLFELBAE_02642 8.68e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
MLFELBAE_02643 5.11e-59 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
MLFELBAE_02644 4.82e-192 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
MLFELBAE_02645 6.64e-233 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MLFELBAE_02646 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MLFELBAE_02647 3.94e-133 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MLFELBAE_02648 5.5e-89 - - - - - - - -
MLFELBAE_02649 4.35e-10 fliT - - N ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
MLFELBAE_02650 5.79e-88 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
MLFELBAE_02651 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MLFELBAE_02652 9.78e-173 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MLFELBAE_02653 2.67e-43 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
MLFELBAE_02654 5.2e-98 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
MLFELBAE_02655 2.8e-108 yviE - - - - - - -
MLFELBAE_02656 5.69e-207 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
MLFELBAE_02657 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
MLFELBAE_02658 2.2e-105 yvyG - - NOU - - - FlgN protein
MLFELBAE_02659 6.14e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
MLFELBAE_02660 1.1e-97 yvyF - - S - - - flagellar protein
MLFELBAE_02661 1.43e-99 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
MLFELBAE_02662 3.56e-57 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
MLFELBAE_02663 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MLFELBAE_02664 5.95e-202 degV - - S - - - protein conserved in bacteria
MLFELBAE_02665 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLFELBAE_02666 3.44e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
MLFELBAE_02667 1.2e-154 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
MLFELBAE_02668 3.83e-230 yvhJ - - K - - - Transcriptional regulator
MLFELBAE_02669 3.12e-233 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
MLFELBAE_02670 4.3e-299 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
MLFELBAE_02671 2.82e-185 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
MLFELBAE_02672 2.46e-148 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
MLFELBAE_02673 0.0 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
MLFELBAE_02674 0.0 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MLFELBAE_02675 4.07e-288 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
MLFELBAE_02676 0.0 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MLFELBAE_02677 4.22e-151 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MLFELBAE_02678 0.0 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
MLFELBAE_02679 0.0 lytB - - D - - - Stage II sporulation protein
MLFELBAE_02680 3.22e-65 - - - - - - - -
MLFELBAE_02681 1.28e-203 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
MLFELBAE_02682 9.76e-88 yvrL - - S - - - Regulatory protein YrvL
MLFELBAE_02683 7.32e-294 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
MLFELBAE_02684 3.78e-21 - - - S - - - YvrJ protein family
MLFELBAE_02685 3.23e-134 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
MLFELBAE_02686 1.67e-50 - - - - - - - -
MLFELBAE_02687 2.7e-172 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLFELBAE_02688 0.0 yvrG - - T - - - Histidine kinase
MLFELBAE_02689 3.79e-219 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
MLFELBAE_02690 4.1e-179 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MLFELBAE_02691 1.36e-214 yvrC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MLFELBAE_02692 1.96e-231 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLFELBAE_02693 7.3e-287 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
MLFELBAE_02694 3.62e-130 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
MLFELBAE_02695 5.58e-289 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
MLFELBAE_02696 1.62e-68 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
MLFELBAE_02697 3.96e-133 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
MLFELBAE_02698 2.03e-192 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
MLFELBAE_02699 8.92e-164 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
MLFELBAE_02700 3.48e-247 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MLFELBAE_02701 1.02e-139 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLFELBAE_02702 1.36e-265 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
MLFELBAE_02703 2.52e-243 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
MLFELBAE_02704 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
MLFELBAE_02705 1.83e-33 - - - S - - - Protein of unknown function (DUF3970)
MLFELBAE_02706 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MLFELBAE_02707 3.11e-201 yuxN - - K - - - Transcriptional regulator
MLFELBAE_02708 4.63e-33 - - - - - - - -
MLFELBAE_02709 0.0 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MLFELBAE_02710 3.17e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLFELBAE_02711 6.82e-308 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MLFELBAE_02712 4.12e-103 dps2 - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
MLFELBAE_02713 5.04e-195 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MLFELBAE_02714 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
MLFELBAE_02715 2.18e-59 - - - S - - - YusW-like protein
MLFELBAE_02716 1.29e-192 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MLFELBAE_02717 2.15e-52 yusU - - S - - - Protein of unknown function (DUF2573)
MLFELBAE_02718 8.47e-241 apbA 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MLFELBAE_02719 4.31e-178 - 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
MLFELBAE_02720 1.52e-206 - - - K - - - Transcriptional regulator
MLFELBAE_02721 1.16e-204 yusT - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
MLFELBAE_02722 1.27e-169 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
MLFELBAE_02723 1.69e-86 yusQ - - S - - - Tautomerase enzyme
MLFELBAE_02724 0.0 yusP - - P - - - Major facilitator superfamily
MLFELBAE_02725 9.65e-92 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
MLFELBAE_02726 4.46e-72 yusN - - M - - - Coat F domain
MLFELBAE_02727 1.31e-57 - - - - - - - -
MLFELBAE_02728 1.48e-263 yusP - - P - - - Major facilitator superfamily
MLFELBAE_02729 6.51e-216 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
MLFELBAE_02730 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
MLFELBAE_02731 9.03e-277 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
MLFELBAE_02732 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
MLFELBAE_02733 7.13e-84 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
MLFELBAE_02734 4.16e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
MLFELBAE_02735 5.16e-54 yusG - - S - - - Protein of unknown function (DUF2553)
MLFELBAE_02736 1.08e-82 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
MLFELBAE_02737 1.64e-72 yusE - - CO - - - Thioredoxin
MLFELBAE_02738 1.29e-76 yusD - - S - - - SCP-2 sterol transfer family
MLFELBAE_02739 3.71e-237 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MLFELBAE_02740 2.08e-138 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
MLFELBAE_02741 1.82e-186 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
MLFELBAE_02742 2.54e-84 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MLFELBAE_02743 3.82e-183 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
MLFELBAE_02744 8.67e-312 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
MLFELBAE_02745 2.31e-298 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MLFELBAE_02746 8.89e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
MLFELBAE_02747 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
MLFELBAE_02748 5.94e-200 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
MLFELBAE_02749 2.61e-105 yncE - - S - - - Protein of unknown function (DUF2691)
MLFELBAE_02750 1.21e-162 - - - Q - - - ubiE/COQ5 methyltransferase family
MLFELBAE_02751 2.05e-256 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
MLFELBAE_02752 5.74e-86 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
MLFELBAE_02755 3.88e-211 - - - K - - - helix_turn_helix, mercury resistance
MLFELBAE_02756 2.33e-238 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
MLFELBAE_02757 4.28e-312 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
MLFELBAE_02758 5.26e-203 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MLFELBAE_02759 3.6e-209 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
MLFELBAE_02760 1.78e-204 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
MLFELBAE_02761 5.89e-173 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
MLFELBAE_02762 3.88e-264 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MLFELBAE_02763 4.09e-217 bsn - - L - - - Ribonuclease
MLFELBAE_02764 9.82e-299 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
MLFELBAE_02765 8.1e-300 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
MLFELBAE_02766 1.23e-273 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
MLFELBAE_02767 2.6e-84 - - - - - - - -
MLFELBAE_02768 1.43e-175 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Aspartate phosphatase response regulator
MLFELBAE_02771 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
MLFELBAE_02772 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
MLFELBAE_02773 3.55e-79 - - - S - - - phosphoglycolate phosphatase activity
MLFELBAE_02774 8.23e-214 yunF - - S - - - Protein of unknown function DUF72
MLFELBAE_02775 3.01e-186 yunE - - S ko:K07090 - ko00000 membrane transporter protein
MLFELBAE_02776 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MLFELBAE_02777 4.76e-168 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
MLFELBAE_02778 4.58e-248 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
MLFELBAE_02779 3.92e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MLFELBAE_02780 3.71e-62 yutD - - S - - - protein conserved in bacteria
MLFELBAE_02781 2.67e-96 yutE - - S - - - Protein of unknown function DUF86
MLFELBAE_02782 5.03e-181 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MLFELBAE_02783 1.5e-109 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
MLFELBAE_02784 1.55e-250 yutH - - S - - - Spore coat protein
MLFELBAE_02785 1.43e-308 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
MLFELBAE_02786 1.55e-249 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MLFELBAE_02787 2.26e-215 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MLFELBAE_02788 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
MLFELBAE_02789 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
MLFELBAE_02790 3.29e-73 yuzD - - S - - - protein conserved in bacteria
MLFELBAE_02791 4.9e-265 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
MLFELBAE_02792 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
MLFELBAE_02793 1.49e-273 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MLFELBAE_02794 5.54e-208 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MLFELBAE_02795 1.38e-82 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
MLFELBAE_02797 1.82e-177 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
MLFELBAE_02798 6.91e-50 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
MLFELBAE_02800 5.3e-44 - - - S - - - Bacteriocin class IId cyclical uberolysin-like
MLFELBAE_02802 1.18e-159 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MLFELBAE_02803 5.92e-93 - - - CP - - - Membrane
MLFELBAE_02804 5.68e-40 - - - - - - - -
MLFELBAE_02805 6.68e-237 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MLFELBAE_02807 1.03e-238 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
MLFELBAE_02808 1.39e-299 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
MLFELBAE_02809 8.54e-46 yuiB - - S - - - Putative membrane protein
MLFELBAE_02810 7.23e-155 yuiC - - S - - - protein conserved in bacteria
MLFELBAE_02811 4.99e-101 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
MLFELBAE_02812 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MLFELBAE_02813 2.01e-276 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
MLFELBAE_02814 3.73e-131 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
MLFELBAE_02815 1.13e-155 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
MLFELBAE_02816 1.21e-209 eSD - - S ko:K07017 - ko00000 Putative esterase
MLFELBAE_02817 7.08e-171 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
MLFELBAE_02818 1.36e-286 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
MLFELBAE_02819 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
MLFELBAE_02820 4.79e-221 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
MLFELBAE_02821 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLFELBAE_02822 3.87e-46 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
MLFELBAE_02823 1.77e-170 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
MLFELBAE_02824 5.7e-261 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
MLFELBAE_02825 2.11e-291 yukF - - QT - - - Transcriptional regulator
MLFELBAE_02826 1.94e-60 yukE - - S - - - Belongs to the WXG100 family
MLFELBAE_02827 5.28e-53 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
MLFELBAE_02828 7.6e-274 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
MLFELBAE_02829 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MLFELBAE_02830 0.0 yueB - - S - - - type VII secretion protein EsaA
MLFELBAE_02831 8.01e-102 yueC - - S - - - Family of unknown function (DUF5383)
MLFELBAE_02832 2.29e-166 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLFELBAE_02833 1.57e-124 yueE - - S ko:K06950 - ko00000 phosphohydrolase
MLFELBAE_02834 1.98e-31 - - - S - - - Protein of unknown function (DUF2642)
MLFELBAE_02835 5.37e-238 yueF - - S - - - transporter activity
MLFELBAE_02836 6.33e-46 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
MLFELBAE_02837 5.46e-51 yueH - - S - - - YueH-like protein
MLFELBAE_02838 7.94e-90 yueI - - S - - - Protein of unknown function (DUF1694)
MLFELBAE_02839 4.65e-134 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
MLFELBAE_02840 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MLFELBAE_02841 6.86e-296 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
MLFELBAE_02842 9.23e-71 yuzC - - - - - - -
MLFELBAE_02843 2.66e-11 - - - S - - - DegQ (SacQ) family
MLFELBAE_02844 1.2e-111 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Polyprenyl synthetase
MLFELBAE_02846 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MLFELBAE_02847 4.85e-15 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MLFELBAE_02848 8.07e-148 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLFELBAE_02849 1.19e-84 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
MLFELBAE_02850 4.2e-79 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
MLFELBAE_02851 1.91e-52 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MLFELBAE_02852 1.23e-101 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MLFELBAE_02853 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MLFELBAE_02854 1.47e-67 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MLFELBAE_02855 5.39e-91 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MLFELBAE_02856 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MLFELBAE_02858 4.39e-218 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MLFELBAE_02859 1.11e-237 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MLFELBAE_02860 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MLFELBAE_02861 4.98e-250 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
MLFELBAE_02862 5.63e-163 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
MLFELBAE_02863 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
MLFELBAE_02864 1.6e-101 yufK - - S - - - Family of unknown function (DUF5366)
MLFELBAE_02865 2.62e-95 yuxK - - S - - - protein conserved in bacteria
MLFELBAE_02866 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
MLFELBAE_02867 2.04e-244 yuxJ - - EGP - - - Major facilitator superfamily
MLFELBAE_02868 3.22e-152 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
MLFELBAE_02869 1.62e-87 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
MLFELBAE_02870 1.49e-291 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MLFELBAE_02871 2.73e-285 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
MLFELBAE_02872 1.22e-54 yugE - - S - - - Domain of unknown function (DUF1871)
MLFELBAE_02873 4.03e-200 yugF - - I - - - Hydrolase
MLFELBAE_02874 3.75e-109 alaR - - K - - - Transcriptional regulator
MLFELBAE_02875 1.68e-266 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
MLFELBAE_02876 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
MLFELBAE_02877 3.14e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
MLFELBAE_02878 1.65e-286 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
MLFELBAE_02879 7.9e-291 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
MLFELBAE_02880 4.34e-152 ycaC - - Q - - - Isochorismatase family
MLFELBAE_02881 2.15e-23 - - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
MLFELBAE_02882 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
MLFELBAE_02884 2.09e-95 yugN - - S - - - YugN-like family
MLFELBAE_02885 9.77e-231 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
MLFELBAE_02886 2.44e-35 mstX - - S - - - Membrane-integrating protein Mistic
MLFELBAE_02887 4.35e-23 - - - - - - - -
MLFELBAE_02888 1.67e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
MLFELBAE_02889 1.63e-296 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
MLFELBAE_02890 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
MLFELBAE_02891 5.43e-98 yugU - - S - - - Uncharacterised protein family UPF0047
MLFELBAE_02892 8.17e-242 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
MLFELBAE_02893 1.61e-55 - - - - - - - -
MLFELBAE_02894 3.68e-178 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
MLFELBAE_02895 4.4e-316 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
MLFELBAE_02896 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
MLFELBAE_02897 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
MLFELBAE_02898 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
MLFELBAE_02899 6.95e-127 yraA 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 DJ-1/PfpI family
MLFELBAE_02900 1.35e-237 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
MLFELBAE_02901 9.96e-251 yubA - - S - - - transporter activity
MLFELBAE_02902 6.56e-187 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MLFELBAE_02904 1.3e-69 yjcN - - - - - - -
MLFELBAE_02905 1.58e-158 - - - G - - - Cupin
MLFELBAE_02906 1.46e-282 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MLFELBAE_02907 2.58e-191 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MLFELBAE_02908 1.06e-156 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
MLFELBAE_02909 2.03e-122 yuaB - - - - - - -
MLFELBAE_02910 1.37e-122 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
MLFELBAE_02911 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
MLFELBAE_02912 7.08e-290 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
MLFELBAE_02913 6.79e-141 - - - S - - - MOSC domain
MLFELBAE_02914 8.91e-106 yuaE - - S - - - DinB superfamily
MLFELBAE_02915 1.96e-109 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
MLFELBAE_02916 5.08e-276 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
MLFELBAE_02917 1.46e-126 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
MLFELBAE_02918 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
MLFELBAE_02919 8.71e-164 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
MLFELBAE_02920 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
MLFELBAE_02921 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MLFELBAE_02922 2.74e-286 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
MLFELBAE_02923 1.8e-248 yerI - - S - - - homoserine kinase type II (protein kinase fold)
MLFELBAE_02924 1.68e-157 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
MLFELBAE_02925 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MLFELBAE_02926 1.81e-60 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MLFELBAE_02927 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MLFELBAE_02928 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MLFELBAE_02929 6.12e-195 yerO - - K - - - Transcriptional regulator
MLFELBAE_02930 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MLFELBAE_02931 4.24e-217 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MLFELBAE_02932 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MLFELBAE_02934 1.31e-200 cylA - - V ko:K01990,ko:K09695,ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
MLFELBAE_02935 6.78e-176 cylB - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
MLFELBAE_02936 5.51e-72 - - - S - - - Protein of unknown function, DUF600
MLFELBAE_02937 1.81e-60 - - - S - - - Protein of unknown function, DUF600
MLFELBAE_02938 1.04e-50 - - - S - - - Protein of unknown function, DUF600
MLFELBAE_02939 5.72e-94 - - - S - - - Protein of unknown function, DUF600
MLFELBAE_02940 1.59e-28 - - - S - - - Colicin immunity protein / pyocin immunity protein
MLFELBAE_02941 2.72e-316 - - - S - - - Bacterial EndoU nuclease
MLFELBAE_02942 3.12e-162 yeeN - - K - - - transcriptional regulatory protein
MLFELBAE_02944 2.67e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
MLFELBAE_02945 1.62e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
MLFELBAE_02946 1.48e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
MLFELBAE_02947 8.73e-127 yesJ - - K - - - Acetyltransferase (GNAT) family
MLFELBAE_02948 4.2e-05 - - - - - - - -
MLFELBAE_02949 1.81e-156 yetF - - S - - - membrane
MLFELBAE_02950 1.11e-72 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
MLFELBAE_02951 7.63e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MLFELBAE_02952 4.42e-197 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MLFELBAE_02953 1.34e-31 - - - S - - - Uncharacterized small protein (DUF2292)
MLFELBAE_02954 1.06e-72 - - - H - - - riboflavin kinase activity
MLFELBAE_02955 2.19e-136 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
MLFELBAE_02956 4.9e-116 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
MLFELBAE_02957 8.18e-263 yetM - - CH - - - FAD binding domain
MLFELBAE_02958 2.38e-252 yetN - - S - - - Protein of unknown function (DUF3900)
MLFELBAE_02959 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
MLFELBAE_02961 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
MLFELBAE_02962 1.02e-188 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
MLFELBAE_02963 6.8e-220 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
MLFELBAE_02964 2.31e-230 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
MLFELBAE_02965 1.46e-284 yfnE - - S - - - Glycosyltransferase like family 2
MLFELBAE_02966 1.2e-239 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
MLFELBAE_02967 2.22e-277 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
MLFELBAE_02968 3.41e-312 yfnA - - E ko:K03294 - ko00000 amino acid
MLFELBAE_02969 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MLFELBAE_02970 2.04e-162 yfmS - - NT - - - chemotaxis protein
MLFELBAE_02971 4.94e-214 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
MLFELBAE_02972 3.45e-265 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
MLFELBAE_02973 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MLFELBAE_02974 8.7e-91 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
MLFELBAE_02975 1.25e-264 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
MLFELBAE_02976 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MLFELBAE_02977 4.37e-265 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
MLFELBAE_02978 8.42e-86 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
MLFELBAE_02979 4.91e-241 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
MLFELBAE_02980 1.1e-30 - - - S - - - Protein of unknown function (DUF3212)
MLFELBAE_02981 4.9e-76 yflT - - S - - - Heat induced stress protein YflT
MLFELBAE_02982 2.18e-306 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
MLFELBAE_02983 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
MLFELBAE_02988 0.0 ywpD - - T - - - Histidine kinase
MLFELBAE_02989 2.49e-193 M1-574 - - T - - - Transcriptional regulatory protein, C terminal
MLFELBAE_02990 0.0 - - - M - - - cell wall anchor domain
MLFELBAE_02991 9.62e-105 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
MLFELBAE_02992 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
MLFELBAE_02993 5.63e-154 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
MLFELBAE_02994 9.72e-227 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
MLFELBAE_02995 8.19e-287 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
MLFELBAE_02996 8.08e-191 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
MLFELBAE_02997 8.63e-279 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
MLFELBAE_02998 9.63e-60 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
MLFELBAE_02999 2.51e-158 yflK - - S - - - protein conserved in bacteria
MLFELBAE_03000 5.84e-21 yflJ - - S - - - Protein of unknown function (DUF2639)
MLFELBAE_03001 1.98e-26 yflI - - - - - - -
MLFELBAE_03002 2.78e-65 yflH - - S - - - Protein of unknown function (DUF3243)
MLFELBAE_03003 6.62e-178 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
MLFELBAE_03004 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
MLFELBAE_03005 7.03e-98 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
MLFELBAE_03006 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
MLFELBAE_03007 8.46e-84 ydhN1 - - S - - - Domain of unknown function (DUF1992)
MLFELBAE_03008 1.43e-104 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
MLFELBAE_03009 8.17e-52 ydgA - - S - - - Spore germination protein gerPA/gerPF
MLFELBAE_03010 7.28e-51 ydgB - - S - - - Spore germination protein gerPA/gerPF
MLFELBAE_03011 1.83e-312 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MLFELBAE_03012 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
MLFELBAE_03013 9.69e-165 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
MLFELBAE_03014 5.91e-158 frp - - C - - - nitroreductase
MLFELBAE_03015 6e-167 yibF - - S - - - YibE/F-like protein
MLFELBAE_03016 5.42e-256 yibE - - S - - - YibE/F-like protein
MLFELBAE_03017 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
MLFELBAE_03018 7.82e-118 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
MLFELBAE_03019 9.13e-239 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
MLFELBAE_03020 3.54e-209 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MLFELBAE_03021 4.11e-174 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MLFELBAE_03022 6.67e-250 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
MLFELBAE_03023 1.47e-41 yfkK - - S - - - Belongs to the UPF0435 family
MLFELBAE_03024 1.69e-112 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MLFELBAE_03025 1.76e-68 yfkI - - S - - - gas vesicle protein
MLFELBAE_03026 1.37e-185 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
MLFELBAE_03027 1.16e-12 - - - - - - - -
MLFELBAE_03028 4.15e-278 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
MLFELBAE_03029 8.42e-239 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
MLFELBAE_03030 5.66e-186 yfkD - - S - - - YfkD-like protein
MLFELBAE_03031 6.07e-188 yfkC - - M - - - Mechanosensitive ion channel
MLFELBAE_03032 1.97e-280 yfkA - - S - - - YfkB-like domain
MLFELBAE_03033 7.99e-37 yfjT - - - - - - -
MLFELBAE_03034 1.78e-198 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
MLFELBAE_03035 2.39e-194 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
MLFELBAE_03037 2.24e-236 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
MLFELBAE_03038 1.72e-208 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MLFELBAE_03039 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MLFELBAE_03040 2.15e-67 - - - S - - - YfzA-like protein
MLFELBAE_03042 2.97e-245 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MLFELBAE_03043 1.11e-115 yfjM - - S - - - Psort location Cytoplasmic, score
MLFELBAE_03044 5.55e-244 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MLFELBAE_03045 3.08e-241 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MLFELBAE_03046 3.96e-274 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MLFELBAE_03047 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MLFELBAE_03048 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
MLFELBAE_03049 6.64e-22 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
MLFELBAE_03050 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MLFELBAE_03051 7.72e-179 glvR - - F ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
MLFELBAE_03052 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MLFELBAE_03053 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
MLFELBAE_03054 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
MLFELBAE_03055 6.47e-81 yfiD3 - - S - - - DoxX
MLFELBAE_03056 6.43e-203 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
MLFELBAE_03057 2.64e-217 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MLFELBAE_03058 1.61e-125 padR - - K - - - transcriptional
MLFELBAE_03059 4.22e-143 - 1.6.5.2 - S ko:K00355 ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
MLFELBAE_03060 1.89e-236 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
MLFELBAE_03061 0.0 - 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
MLFELBAE_03062 1.17e-60 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
MLFELBAE_03063 1.14e-128 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
MLFELBAE_03064 0.0 yfiU - - EGP - - - the major facilitator superfamily
MLFELBAE_03065 1.38e-108 yfiV - - K - - - transcriptional
MLFELBAE_03066 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MLFELBAE_03067 5.56e-213 yfhB - - S - - - PhzF family
MLFELBAE_03068 8.22e-138 yfhC - - C - - - nitroreductase
MLFELBAE_03069 3.61e-34 yfhD - - S - - - YfhD-like protein
MLFELBAE_03070 1.72e-214 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
MLFELBAE_03071 1.49e-181 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
MLFELBAE_03072 1.12e-69 yfhH - - S - - - Protein of unknown function (DUF1811)
MLFELBAE_03073 4.06e-268 yfhI - - EGP - - - -transporter
MLFELBAE_03075 2.45e-216 mpr - - M - - - Belongs to the peptidase S1B family
MLFELBAE_03076 2.57e-59 yfhJ - - S - - - WVELL protein
MLFELBAE_03077 9.84e-123 yfhK - - T - - - Bacterial SH3 domain homologues
MLFELBAE_03078 1.48e-57 yfhL - - S - - - SdpI/YhfL protein family
MLFELBAE_03079 9.66e-219 - - - S - - - Alpha/beta hydrolase family
MLFELBAE_03080 1.35e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
MLFELBAE_03081 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
MLFELBAE_03082 2.94e-236 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
MLFELBAE_03083 1.4e-260 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
MLFELBAE_03084 2.54e-50 yfhS - - - - - - -
MLFELBAE_03085 3.81e-173 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLFELBAE_03086 2.38e-06 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
MLFELBAE_03087 1.4e-49 ygaB - - S - - - YgaB-like protein
MLFELBAE_03088 2.32e-135 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
MLFELBAE_03089 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
MLFELBAE_03090 5.48e-239 ygaE - - S - - - Membrane
MLFELBAE_03091 6.86e-314 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
MLFELBAE_03092 1.39e-111 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
MLFELBAE_03093 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
MLFELBAE_03094 4.67e-75 ygzB - - S - - - UPF0295 protein
MLFELBAE_03095 6.49e-212 ygxA - - S - - - Nucleotidyltransferase-like
MLFELBAE_03096 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
MLFELBAE_03097 6.89e-143 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLFELBAE_03098 1.95e-265 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MLFELBAE_03099 4.19e-50 yraG - - - ko:K06440 - ko00000 -
MLFELBAE_03100 4.76e-84 yraF - - M - - - Spore coat protein
MLFELBAE_03101 2.5e-281 adhB 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MLFELBAE_03102 9.81e-33 yraE - - - ko:K06440 - ko00000 -
MLFELBAE_03103 2.84e-63 yraD - - M ko:K06439 - ko00000 Spore coat protein
MLFELBAE_03104 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MLFELBAE_03105 1.29e-202 ydeK - - EG - - - -transporter
MLFELBAE_03106 1.2e-132 ydeS - - K - - - Transcriptional regulator
MLFELBAE_03107 7.31e-242 ydeR - - EGP - - - Uncharacterised MFS-type transporter YbfB
MLFELBAE_03109 2.95e-146 paiB - - K ko:K07734 - ko00000,ko03000 Transcriptional regulator
MLFELBAE_03110 0.0 - - - K ko:K00375 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
MLFELBAE_03111 7.9e-288 nhaC_1 - - C - - - antiporter
MLFELBAE_03112 7.29e-87 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
MLFELBAE_03113 5.46e-259 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
MLFELBAE_03114 9.38e-209 - - - S - - - Sodium Bile acid symporter family
MLFELBAE_03115 6.9e-298 - - - G - - - Haloacid dehalogenase-like hydrolase
MLFELBAE_03116 7.44e-191 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7 - H ko:K00941,ko:K14153 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
MLFELBAE_03117 4.34e-189 - - - Q - - - ubiE/COQ5 methyltransferase family
MLFELBAE_03118 3.94e-250 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MLFELBAE_03119 2.61e-110 - - - F - - - nucleoside 2-deoxyribosyltransferase
MLFELBAE_03120 4.32e-73 ydeH - - - - - - -
MLFELBAE_03121 1.01e-254 cfr 2.1.1.224 - J ko:K15632 - ko00000,ko01000,ko01504,ko03009 Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
MLFELBAE_03123 9.44e-190 dapA7 4.3.3.7 - EM ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Dihydrodipicolinate synthetase family
MLFELBAE_03125 5e-253 trkA - - P ko:K07222 - ko00000 Oxidoreductase
MLFELBAE_03126 1.71e-214 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
MLFELBAE_03127 6.64e-50 - - - E ko:K07032 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MLFELBAE_03128 0.0 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
MLFELBAE_03131 1.49e-84 - - - G - - - Cupin domain
MLFELBAE_03132 2.47e-101 - - - S - - - DinB superfamily
MLFELBAE_03133 3.56e-234 - - - S - - - Patatin-like phospholipase
MLFELBAE_03134 1.58e-299 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
MLFELBAE_03135 2.98e-216 ybfA - - K - - - FR47-like protein
MLFELBAE_03136 9.96e-69 - - - K - - - Transcriptional regulator PadR-like family
MLFELBAE_03137 2.56e-134 - - - S - - - Protein of unknown function (DUF2812)
MLFELBAE_03138 1.5e-158 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
MLFELBAE_03139 9.77e-264 - - - EGP ko:K18926 - ko00000,ko00002,ko02000 Major Facilitator Superfamily
MLFELBAE_03140 3.37e-96 - - - P ko:K03449 - ko00000,ko02000 transporter
MLFELBAE_03141 5.21e-188 - 1.8.5.5 - C ko:K08352 ko00920,ko01120,map00920,map01120 ko00000,ko00001,ko01000,ko02000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MLFELBAE_03142 2.17e-99 yvbU - - K - - - Transcriptional regulator
MLFELBAE_03143 2.07e-102 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
MLFELBAE_03144 3.87e-42 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
MLFELBAE_03145 2.7e-145 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
MLFELBAE_03146 3.91e-95 ywnA - - K - - - Transcriptional regulator
MLFELBAE_03147 3.46e-84 - - - S - - - YjbR
MLFELBAE_03148 2.05e-94 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
MLFELBAE_03149 1.43e-110 yddJ - - S - - - Domain of unknown function with cystatin-like fold (DUF4467)
MLFELBAE_03150 6.04e-65 ohrR - - K - - - Transcriptional regulator
MLFELBAE_03151 0.0 - - - EGP ko:K03761,ko:K03762 - ko00000,ko02000 Transporter
MLFELBAE_03152 1.13e-193 - - - S - - - Serine aminopeptidase, S33
MLFELBAE_03153 2.73e-92 lrpA - - K ko:K03719 - ko00000,ko03000,ko03036 transcriptional
MLFELBAE_03154 1.81e-180 yddR - - S - - - Zn-dependent hydrolases of the beta-lactamase fold
MLFELBAE_03155 6.17e-96 - - - S - - - SnoaL-like polyketide cyclase
MLFELBAE_03156 1.35e-124 yrkL - - S ko:K11748 - ko00000,ko02000 Flavodoxin-like fold
MLFELBAE_03164 1.74e-75 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
MLFELBAE_03165 1.78e-21 - - - - - - - -
MLFELBAE_03166 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
MLFELBAE_03167 5.75e-141 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
MLFELBAE_03168 1.14e-180 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLFELBAE_03169 7.1e-111 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
MLFELBAE_03170 9.77e-71 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
MLFELBAE_03171 3.6e-241 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
MLFELBAE_03172 1.73e-89 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
MLFELBAE_03173 1.09e-75 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
MLFELBAE_03174 6.07e-186 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
MLFELBAE_03175 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
MLFELBAE_03176 6.68e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
MLFELBAE_03177 4.66e-278 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MLFELBAE_03178 6.39e-235 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
MLFELBAE_03179 5.17e-74 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MLFELBAE_03180 2.08e-138 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
MLFELBAE_03181 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
MLFELBAE_03182 2.18e-96 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
MLFELBAE_03183 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MLFELBAE_03184 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MLFELBAE_03185 2.16e-258 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
MLFELBAE_03186 6.46e-74 ydbP - - CO - - - Thioredoxin
MLFELBAE_03187 2e-160 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MLFELBAE_03188 6.58e-14 - - - S - - - Fur-regulated basic protein A
MLFELBAE_03189 1.13e-15 - - - S - - - Fur-regulated basic protein B
MLFELBAE_03190 7.2e-260 ydbM - - I - - - acyl-CoA dehydrogenase
MLFELBAE_03191 2.29e-70 ydbL - - - - - - -
MLFELBAE_03192 2.44e-167 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MLFELBAE_03193 9.66e-221 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MLFELBAE_03194 8.61e-231 ydbI - - S - - - AI-2E family transporter
MLFELBAE_03195 3.91e-287 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MLFELBAE_03196 3.67e-153 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
MLFELBAE_03197 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
MLFELBAE_03198 8.63e-252 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
MLFELBAE_03199 1.64e-199 ydbD - - P ko:K07217 - ko00000 Catalase
MLFELBAE_03200 2.58e-82 ydbC - - S - - - Domain of unknown function (DUF4937
MLFELBAE_03201 9.34e-85 ydbB - - G - - - Cupin domain
MLFELBAE_03202 6.55e-10 gsiB - - S ko:K06884 - ko00000 general stress protein
MLFELBAE_03203 5.55e-179 ydbA - - P - - - EcsC protein family
MLFELBAE_03204 6.77e-70 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
MLFELBAE_03205 1.31e-94 yvaD - - S - - - Family of unknown function (DUF5360)
MLFELBAE_03206 1.95e-45 ydaT - - - - - - -
MLFELBAE_03208 1.87e-288 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
MLFELBAE_03209 2.14e-53 - - - - - - - -
MLFELBAE_03210 3.47e-129 - - - - - - - -
MLFELBAE_03211 7.25e-114 - - - - - - - -
MLFELBAE_03213 1.81e-17 - - - - - - - -
MLFELBAE_03216 8.8e-72 - - - K - - - acetyltransferase
MLFELBAE_03217 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
MLFELBAE_03218 9.21e-99 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
MLFELBAE_03219 0.0 ydaO - - E - - - amino acid
MLFELBAE_03220 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
MLFELBAE_03221 1.85e-302 ydaM - - M - - - Glycosyl transferase family group 2
MLFELBAE_03222 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
MLFELBAE_03223 6.29e-188 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
MLFELBAE_03224 8.41e-260 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
MLFELBAE_03225 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MLFELBAE_03226 1.61e-97 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
MLFELBAE_03227 5.59e-64 ydzA - - EGP - - - Domain of unknown function (DUF3817)
MLFELBAE_03228 4.39e-177 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
MLFELBAE_03229 1.83e-101 ydaG - - S - - - general stress protein
MLFELBAE_03230 6.7e-148 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MLFELBAE_03231 2.75e-125 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
MLFELBAE_03232 3.82e-207 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLFELBAE_03233 0.0 ydaB - - IQ - - - acyl-CoA ligase
MLFELBAE_03234 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
MLFELBAE_03235 1.22e-219 ycsN - - S - - - Oxidoreductase
MLFELBAE_03236 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
MLFELBAE_03237 1.11e-70 yczJ - - S - - - biosynthesis
MLFELBAE_03239 5.26e-148 ycsK - - E - - - anatomical structure formation involved in morphogenesis
MLFELBAE_03240 4.65e-167 kipR - - K - - - Transcriptional regulator
MLFELBAE_03241 3.45e-240 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
MLFELBAE_03242 1.98e-176 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
MLFELBAE_03243 2.07e-193 ycsI - - S - - - Belongs to the D-glutamate cyclase family
MLFELBAE_03244 1.32e-271 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
MLFELBAE_03245 6.12e-181 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
MLFELBAE_03246 2.69e-177 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
MLFELBAE_03248 3.38e-86 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
MLFELBAE_03249 1.16e-263 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
MLFELBAE_03250 1.38e-93 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
MLFELBAE_03251 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
MLFELBAE_03252 9.6e-73 - - - - - - - -
MLFELBAE_03253 8.6e-138 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
MLFELBAE_03254 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
MLFELBAE_03255 1.39e-129 ycnI - - S - - - protein conserved in bacteria
MLFELBAE_03256 2.4e-186 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLFELBAE_03257 8.27e-191 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
MLFELBAE_03258 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MLFELBAE_03259 7.59e-288 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MLFELBAE_03260 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MLFELBAE_03261 1.37e-70 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MLFELBAE_03262 1.97e-59 ycnE - - S - - - Monooxygenase
MLFELBAE_03263 1.38e-174 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Nitroreductase family
MLFELBAE_03264 1.05e-195 ycnC - - K - - - Transcriptional regulator
MLFELBAE_03265 2.1e-315 ycnB - - EGP - - - the major facilitator superfamily
MLFELBAE_03266 6.82e-224 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
MLFELBAE_03267 1.61e-175 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MLFELBAE_03268 1.64e-211 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLFELBAE_03269 7.78e-211 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLFELBAE_03270 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
MLFELBAE_03272 1.2e-99 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
MLFELBAE_03273 0.0 yclK - - T - - - COG0642 Signal transduction histidine kinase
MLFELBAE_03274 9.08e-165 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLFELBAE_03275 1.56e-312 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
MLFELBAE_03276 1.74e-153 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
MLFELBAE_03277 0.0 yxeQ - - S - - - MmgE/PrpD family
MLFELBAE_03278 4.14e-278 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
MLFELBAE_03279 1.95e-170 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MLFELBAE_03280 6.05e-148 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
MLFELBAE_03281 1.56e-183 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
MLFELBAE_03282 3.64e-119 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MLFELBAE_03283 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLFELBAE_03284 9.23e-249 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
MLFELBAE_03285 1.98e-300 gerKC - - S ko:K06297 - ko00000 spore germination
MLFELBAE_03286 0.0 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
MLFELBAE_03288 0.0 yclG - - M - - - Pectate lyase superfamily protein
MLFELBAE_03289 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
MLFELBAE_03290 8.64e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MLFELBAE_03291 3.9e-303 - - - G ko:K08191,ko:K08194 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
MLFELBAE_03292 1.34e-188 - 4.2.1.118 - G ko:K15652 ko00400,ko01110,ko01130,map00400,map01110,map01130 ko00000,ko00001,ko01000 Xylose isomerase-like TIM barrel
MLFELBAE_03293 1.3e-138 tmrB - - S - - - AAA domain
MLFELBAE_03294 6.96e-07 - - - S - - - Bacillus cereus group antimicrobial protein
MLFELBAE_03295 7.44e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MLFELBAE_03296 3.22e-146 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
MLFELBAE_03297 4.47e-312 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
MLFELBAE_03298 6.95e-191 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
MLFELBAE_03299 1.11e-147 ycgF - - E - - - Lysine exporter protein LysE YggA
MLFELBAE_03300 4.01e-100 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
MLFELBAE_03301 0.0 mdr - - EGP - - - the major facilitator superfamily
MLFELBAE_03302 3.82e-227 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
MLFELBAE_03303 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
MLFELBAE_03304 1.08e-106 ycgB - - - - - - -
MLFELBAE_03305 1.8e-290 ycgA - - S - - - Membrane
MLFELBAE_03306 1.87e-269 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
MLFELBAE_03307 7e-211 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
MLFELBAE_03308 2.45e-185 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
MLFELBAE_03309 1.28e-292 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
MLFELBAE_03310 5.07e-62 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MLFELBAE_03311 5.81e-242 - - - EGP - - - Uncharacterised MFS-type transporter YbfB
MLFELBAE_03312 1.79e-267 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
MLFELBAE_03313 3.9e-245 yceH - - P - - - Belongs to the TelA family
MLFELBAE_03314 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
MLFELBAE_03315 2.12e-178 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
MLFELBAE_03316 2.46e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
MLFELBAE_03317 3.63e-136 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
MLFELBAE_03318 1.16e-139 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
MLFELBAE_03319 1.2e-237 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLFELBAE_03320 1.19e-174 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MLFELBAE_03321 1.4e-170 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MLFELBAE_03322 1.48e-213 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
MLFELBAE_03323 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
MLFELBAE_03324 1.05e-179 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
MLFELBAE_03325 2.86e-248 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
MLFELBAE_03326 8.88e-122 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
MLFELBAE_03327 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MLFELBAE_03328 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MLFELBAE_03329 1.38e-227 ycdA - - S - - - Domain of unknown function (DUF5105)
MLFELBAE_03330 1.08e-218 yccK - - C - - - Aldo keto reductase
MLFELBAE_03331 1.68e-252 yccF - - K ko:K07039 - ko00000 SEC-C motif
MLFELBAE_03332 5.23e-144 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
MLFELBAE_03333 5.04e-257 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
MLFELBAE_03334 8.93e-130 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
MLFELBAE_03335 5.62e-310 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
MLFELBAE_03336 1.21e-266 ycbU - - E - - - Selenocysteine lyase
MLFELBAE_03337 5.93e-155 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MLFELBAE_03338 2.86e-159 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MLFELBAE_03339 8.68e-36 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MLFELBAE_03340 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
MLFELBAE_03341 1.05e-101 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
MLFELBAE_03342 1.63e-82 ycbP - - S - - - Protein of unknown function (DUF2512)
MLFELBAE_03343 1.54e-73 ydfQ - - CO - - - Thioredoxin
MLFELBAE_03344 9.37e-83 ydfP - - S ko:K15977 - ko00000 DoxX
MLFELBAE_03345 5.06e-234 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
MLFELBAE_03346 6.96e-145 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
MLFELBAE_03347 3.67e-199 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MLFELBAE_03348 5.89e-36 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
MLFELBAE_03349 2.88e-44 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
MLFELBAE_03350 5.81e-221 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
MLFELBAE_03351 7.61e-280 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MLFELBAE_03352 3.19e-240 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
MLFELBAE_03353 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
MLFELBAE_03354 1.06e-232 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
MLFELBAE_03355 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
MLFELBAE_03356 5.02e-256 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
MLFELBAE_03357 8.22e-272 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MLFELBAE_03358 2.35e-244 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
MLFELBAE_03359 1.23e-54 ybfN - - - - - - -
MLFELBAE_03360 3.05e-194 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
MLFELBAE_03361 8.6e-113 ybfM - - S - - - SNARE associated Golgi protein
MLFELBAE_03362 1.56e-120 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MLFELBAE_03363 9.69e-273 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MLFELBAE_03364 2.59e-256 ypjH - - C ko:K08317 - ko00000,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
MLFELBAE_03365 1.69e-107 - - - K - - - Helix-turn-helix XRE-family like proteins
MLFELBAE_03366 2.44e-45 - - - - - - - -
MLFELBAE_03367 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
MLFELBAE_03369 1.66e-266 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
MLFELBAE_03370 5.8e-23 - - - S - - - Protein of unknown function (DUF2651)
MLFELBAE_03371 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
MLFELBAE_03372 8.53e-213 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
MLFELBAE_03375 4.86e-60 - - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MLFELBAE_03376 0.0 ybeC - - E - - - amino acid
MLFELBAE_03377 7.84e-55 ybyB - - - - - - -
MLFELBAE_03378 1.3e-146 yqeB - - - - - - -
MLFELBAE_03379 2.48e-52 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
MLFELBAE_03380 4.28e-102 - - - S - - - Domain of unknown function (DUF4879)
MLFELBAE_03381 6.02e-51 - - - Q - - - Dimerisation domain
MLFELBAE_03382 0.0 - - - Q - - - TIGRFAM amino acid adenylation domain
MLFELBAE_03383 1.57e-114 - - - Q - - - Flavin containing amine oxidoreductase
MLFELBAE_03384 0.0 - - - Q - - - Polyketide synthase modules and related proteins
MLFELBAE_03385 0.0 - - - Q - - - Beta-ketoacyl synthase
MLFELBAE_03386 3.86e-150 - 2.3.1.39 - I ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 PFAM Acyl transferase
MLFELBAE_03387 0.0 - - - Q - - - Non-ribosomal peptide synthetase modules and related proteins
MLFELBAE_03388 0.0 - - - Q - - - Non-ribosomal peptide synthetase modules and related proteins
MLFELBAE_03389 1.97e-73 - - - Q - - - Thioesterase domain
MLFELBAE_03390 1.62e-19 - - - - - - - -
MLFELBAE_03391 7.64e-154 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
MLFELBAE_03392 4.3e-184 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
MLFELBAE_03393 2.14e-170 yfiL - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MLFELBAE_03394 1.24e-104 - - - KT - - - helix_turn_helix, Lux Regulon
MLFELBAE_03395 1.01e-131 - - - T - - - Histidine kinase
MLFELBAE_03396 5.24e-116 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
MLFELBAE_03397 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
MLFELBAE_03398 2.29e-92 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MLFELBAE_03399 1.41e-67 - - - S ko:K06518 - ko00000,ko02000 LrgA family
MLFELBAE_03400 1.49e-135 yxaC - - M - - - effector of murein hydrolase
MLFELBAE_03401 3.09e-208 dkgB - - S - - - Aldo/keto reductase family
MLFELBAE_03402 1.06e-165 ybdO - - S - - - Domain of unknown function (DUF4885)
MLFELBAE_03403 4.35e-124 ybdN - - - - - - -
MLFELBAE_03404 2.02e-138 - - - S - - - ABC-2 family transporter protein
MLFELBAE_03405 8.7e-199 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MLFELBAE_03406 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MLFELBAE_03407 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MLFELBAE_03408 5.88e-290 ybbR - - S - - - protein conserved in bacteria
MLFELBAE_03409 9e-188 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MLFELBAE_03410 6.45e-151 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
MLFELBAE_03411 4.59e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MLFELBAE_03417 7.84e-101 ybbK - - S - - - Protein of unknown function (DUF523)
MLFELBAE_03418 8.67e-111 ybbJ - - J - - - acetyltransferase
MLFELBAE_03419 1.34e-207 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MLFELBAE_03420 1.75e-311 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MLFELBAE_03421 1.18e-313 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
MLFELBAE_03422 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
MLFELBAE_03423 9.1e-300 ybbC - - S - - - protein conserved in bacteria
MLFELBAE_03424 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
MLFELBAE_03425 8.55e-220 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
MLFELBAE_03426 8.92e-226 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLFELBAE_03427 2.89e-229 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLFELBAE_03428 1.16e-144 ybbA - - S ko:K07017 - ko00000 Putative esterase
MLFELBAE_03429 4.41e-222 ybaS - - S - - - Na -dependent transporter
MLFELBAE_03430 2.25e-287 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
MLFELBAE_03431 9.77e-257 - 1.1.1.14, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00008 ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
MLFELBAE_03432 3.68e-229 suhB 3.1.3.25, 3.1.3.7 - G ko:K01082,ko:K01092 ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070 ko00000,ko00001,ko00002,ko01000,ko03016 inositol monophosphate 1-phosphatase activity
MLFELBAE_03433 2.57e-313 gabT 2.6.1.19 - E ko:K00823 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MLFELBAE_03434 5.72e-282 glcP1 - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
MLFELBAE_03435 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MLFELBAE_03436 5.16e-135 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MLFELBAE_03437 8.1e-199 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MLFELBAE_03438 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MLFELBAE_03439 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MLFELBAE_03440 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
MLFELBAE_03441 3.84e-28 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
MLFELBAE_03442 6.13e-140 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLFELBAE_03443 1.02e-117 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
MLFELBAE_03444 6.98e-53 yhdB - - S - - - YhdB-like protein
MLFELBAE_03445 4.18e-71 yhdC - - S - - - Protein of unknown function (DUF3889)
MLFELBAE_03446 1.41e-295 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
MLFELBAE_03447 1.32e-96 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
MLFELBAE_03448 0.0 ygxB - - M - - - Conserved TM helix
MLFELBAE_03449 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
MLFELBAE_03450 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
MLFELBAE_03451 2.62e-176 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
MLFELBAE_03452 7e-210 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
MLFELBAE_03453 1.64e-261 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
MLFELBAE_03454 9.14e-205 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLFELBAE_03455 8.9e-317 yhdG - - E ko:K03294 - ko00000 amino acid
MLFELBAE_03456 2.07e-267 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MLFELBAE_03457 8.62e-59 yhdK - - S - - - Sigma-M inhibitor protein
MLFELBAE_03458 6.88e-257 yhdL - - S - - - Sigma factor regulator N-terminal
MLFELBAE_03459 4.6e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MLFELBAE_03460 3.75e-141 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MLFELBAE_03461 3.94e-307 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
MLFELBAE_03462 1.19e-93 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
MLFELBAE_03463 8.17e-286 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
MLFELBAE_03464 1.35e-301 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MLFELBAE_03465 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
MLFELBAE_03466 2.12e-72 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MLFELBAE_03467 8.59e-80 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MLFELBAE_03468 1.28e-165 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
MLFELBAE_03469 1.45e-08 yhdX - - S - - - Uncharacterized protein YhdX
MLFELBAE_03470 6.68e-262 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
MLFELBAE_03471 5.67e-178 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
MLFELBAE_03472 1.7e-201 nodB1 - - G - - - deacetylase
MLFELBAE_03473 1.19e-197 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
MLFELBAE_03474 1.22e-114 pksA - - K - - - Transcriptional regulator
MLFELBAE_03475 1.33e-124 ymcC - - S - - - Membrane
MLFELBAE_03476 2.91e-109 - - - T - - - universal stress protein
MLFELBAE_03477 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
MLFELBAE_03478 0.0 yheH - - V ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
MLFELBAE_03479 3.31e-143 yheG - - GM - - - NAD(P)H-binding
MLFELBAE_03481 9.47e-39 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
MLFELBAE_03482 8.64e-49 yheE - - S - - - Family of unknown function (DUF5342)
MLFELBAE_03483 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
MLFELBAE_03484 1.32e-273 yheC - - HJ - - - YheC/D like ATP-grasp
MLFELBAE_03485 2.25e-263 yheB - - S - - - Belongs to the UPF0754 family
MLFELBAE_03486 2.32e-70 yheA - - S - - - Belongs to the UPF0342 family
MLFELBAE_03487 2.37e-256 yhaZ - - L - - - DNA alkylation repair enzyme
MLFELBAE_03488 2.95e-205 yhaX - - S - - - haloacid dehalogenase-like hydrolase
MLFELBAE_03489 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
MLFELBAE_03490 5.77e-316 - 1.14.13.59 - Q ko:K03897 ko00310,ko01120,map00310,map01120 ko00000,ko00001,ko01000 L-lysine 6-monooxygenase (NADPH-requiring)
MLFELBAE_03491 6.67e-265 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
MLFELBAE_03492 1.87e-113 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
MLFELBAE_03494 4.11e-175 yhaR - - I - - - enoyl-CoA hydratase
MLFELBAE_03495 7.01e-20 - - - S - - - YhzD-like protein
MLFELBAE_03496 3.92e-215 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MLFELBAE_03497 1.13e-275 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
MLFELBAE_03498 4.5e-301 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
MLFELBAE_03499 0.0 yhaN - - L - - - AAA domain
MLFELBAE_03500 2.48e-226 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
MLFELBAE_03501 2.02e-43 yhaL - - S - - - Sporulation protein YhaL
MLFELBAE_03502 2.41e-235 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
MLFELBAE_03503 4.33e-189 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
MLFELBAE_03504 9.61e-217 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
MLFELBAE_03505 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
MLFELBAE_03506 3.14e-311 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MLFELBAE_03507 1.43e-290 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
MLFELBAE_03508 5.76e-243 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
MLFELBAE_03509 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
MLFELBAE_03510 5.95e-75 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
MLFELBAE_03511 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MLFELBAE_03512 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MLFELBAE_03513 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
MLFELBAE_03514 2.01e-285 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
MLFELBAE_03515 8.22e-289 yciC - - S - - - GTPases (G3E family)
MLFELBAE_03516 1.29e-283 fdh 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MLFELBAE_03517 2.67e-96 yckC - - S - - - membrane
MLFELBAE_03518 1.92e-67 - - - S - - - Protein of unknown function (DUF2680)
MLFELBAE_03519 8.02e-114 yckE 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MLFELBAE_03520 3.1e-242 yckE 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MLFELBAE_03521 6.79e-91 nin - - S - - - Competence protein J (ComJ)
MLFELBAE_03522 1.88e-101 nucA - - M - - - Deoxyribonuclease NucA/NucB
MLFELBAE_03523 3.11e-124 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
MLFELBAE_03524 1.1e-139 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
MLFELBAE_03525 1.38e-82 hxlR - - K - - - transcriptional
MLFELBAE_03526 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLFELBAE_03527 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLFELBAE_03528 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
MLFELBAE_03529 3.56e-179 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
MLFELBAE_03530 8.58e-316 - - - E - - - Aminotransferase class I and II
MLFELBAE_03531 3.86e-84 - - - S - - - YcxB-like protein
MLFELBAE_03532 4.54e-216 ycxC - - EG - - - EamA-like transporter family
MLFELBAE_03533 5.41e-310 ycxD - - K - - - GntR family transcriptional regulator
MLFELBAE_03534 4.52e-168 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
MLFELBAE_03535 2.99e-142 yczE - - S ko:K07149 - ko00000 membrane
MLFELBAE_03536 2.78e-169 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
MLFELBAE_03537 2.9e-152 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
MLFELBAE_03538 3.14e-184 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
MLFELBAE_03539 3.45e-205 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
MLFELBAE_03540 3.44e-130 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
MLFELBAE_03541 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
MLFELBAE_03542 2.83e-52 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
MLFELBAE_03543 3.51e-102 yclD - - - - - - -
MLFELBAE_03544 2.03e-67 yerC - - S - - - protein conserved in bacteria
MLFELBAE_03545 7.32e-248 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
MLFELBAE_03546 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
MLFELBAE_03547 8.43e-34 - - - S - - - Protein of unknown function (DUF2892)
MLFELBAE_03548 1.4e-298 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
MLFELBAE_03549 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
MLFELBAE_03550 7.3e-137 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MLFELBAE_03551 5.33e-244 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
MLFELBAE_03552 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MLFELBAE_03553 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MLFELBAE_03554 1.15e-167 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MLFELBAE_03555 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MLFELBAE_03556 7.13e-168 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
MLFELBAE_03557 5.23e-314 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MLFELBAE_03558 4.56e-287 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MLFELBAE_03559 1.13e-108 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MLFELBAE_03560 6.56e-40 yebG - - S - - - NETI protein
MLFELBAE_03561 4.41e-119 yebE - - S - - - UPF0316 protein
MLFELBAE_03563 8.42e-166 yebC - - M - - - Membrane
MLFELBAE_03564 1.23e-269 pbuG - - S ko:K06901 - ko00000,ko02000 permease
MLFELBAE_03565 1.56e-315 - - - S - - - Domain of unknown function (DUF4179)
MLFELBAE_03566 6.63e-122 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MLFELBAE_03567 4.04e-166 - - - K - - - Acetyltransferase (GNAT) domain
MLFELBAE_03568 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
MLFELBAE_03569 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
MLFELBAE_03570 1.62e-276 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
MLFELBAE_03571 5.62e-226 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
MLFELBAE_03572 7.15e-198 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MLFELBAE_03573 4.33e-315 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
MLFELBAE_03574 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
MLFELBAE_03575 2.02e-47 ydjO - - S - - - Cold-inducible protein YdjO
MLFELBAE_03577 1.23e-195 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
MLFELBAE_03578 7.91e-83 ydjM - - M - - - Lytic transglycolase
MLFELBAE_03579 8.25e-248 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
MLFELBAE_03580 1.87e-113 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MLFELBAE_03581 1.13e-192 rsiV - - S - - - Protein of unknown function (DUF3298)
MLFELBAE_03582 0.0 oatA - - I - - - Acyltransferase family
MLFELBAE_03583 7.67e-199 ydjI - - S - - - virion core protein (lumpy skin disease virus)
MLFELBAE_03584 2.24e-162 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
MLFELBAE_03585 1.55e-229 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MLFELBAE_03586 1.36e-146 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
MLFELBAE_03587 5.98e-40 yjdJ - - S - - - Domain of unknown function (DUF4306)
MLFELBAE_03588 2.45e-220 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
MLFELBAE_03589 1.82e-316 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
MLFELBAE_03590 1.19e-255 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
MLFELBAE_03591 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
MLFELBAE_03592 7.07e-51 - - - S - - - Protein of unknown function (DUF4064)
MLFELBAE_03593 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MLFELBAE_03594 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MLFELBAE_03595 8.26e-165 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
MLFELBAE_03596 1.11e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
MLFELBAE_03597 5.74e-161 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MLFELBAE_03598 1.72e-29 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MLFELBAE_03599 1.29e-149 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MLFELBAE_03600 2.95e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
MLFELBAE_03601 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
MLFELBAE_03602 5.33e-244 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MLFELBAE_03603 1.41e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MLFELBAE_03604 5.89e-162 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
MLFELBAE_03605 9.02e-113 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
MLFELBAE_03606 3.28e-232 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MLFELBAE_03609 2.14e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
MLFELBAE_03610 1.14e-83 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
MLFELBAE_03611 3.84e-257 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
MLFELBAE_03612 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
MLFELBAE_03613 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MLFELBAE_03614 3.12e-250 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
MLFELBAE_03615 8.6e-251 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
MLFELBAE_03616 1.01e-159 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MLFELBAE_03617 3.02e-111 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MLFELBAE_03618 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MLFELBAE_03619 3.16e-151 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
MLFELBAE_03620 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
MLFELBAE_03621 4.11e-95 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MLFELBAE_03622 2.04e-172 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MLFELBAE_03623 4.03e-115 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
MLFELBAE_03624 1.39e-150 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
MLFELBAE_03625 3.77e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MLFELBAE_03626 1.28e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
MLFELBAE_03627 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MLFELBAE_03628 8.66e-161 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MLFELBAE_03629 2.33e-103 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MLFELBAE_03630 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MLFELBAE_03631 7.25e-140 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
MLFELBAE_03632 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MLFELBAE_03633 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MLFELBAE_03634 5.94e-46 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
MLFELBAE_03635 9.47e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MLFELBAE_03636 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MLFELBAE_03637 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MLFELBAE_03638 2.35e-286 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MLFELBAE_03639 2.33e-239 ybaC - - S - - - Alpha/beta hydrolase family
MLFELBAE_03640 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
MLFELBAE_03641 1.77e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MLFELBAE_03642 3.68e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
MLFELBAE_03643 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MLFELBAE_03644 9.5e-201 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MLFELBAE_03645 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MLFELBAE_03646 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MLFELBAE_03647 1.69e-151 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MLFELBAE_03648 1.38e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MLFELBAE_03649 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
MLFELBAE_03650 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MLFELBAE_03651 2.55e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MLFELBAE_03652 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MLFELBAE_03653 5.43e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MLFELBAE_03654 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MLFELBAE_03655 1.08e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MLFELBAE_03656 3.14e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MLFELBAE_03657 8.29e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MLFELBAE_03658 4.54e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MLFELBAE_03659 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
MLFELBAE_03660 5.15e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
MLFELBAE_03661 7.75e-296 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MLFELBAE_03662 4.34e-158 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MLFELBAE_03663 2.32e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
MLFELBAE_03664 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MLFELBAE_03665 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
MLFELBAE_03666 1.54e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MLFELBAE_03667 2.28e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MLFELBAE_03668 4.94e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MLFELBAE_03669 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
MLFELBAE_03670 3.05e-199 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MLFELBAE_03671 4.91e-190 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MLFELBAE_03672 2.77e-178 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MLFELBAE_03673 8.74e-182 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MLFELBAE_03674 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MLFELBAE_03675 1.49e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
MLFELBAE_03676 2.06e-184 ybaJ - - Q - - - Methyltransferase domain
MLFELBAE_03677 1.56e-108 yizA - - S - - - Damage-inducible protein DinB
MLFELBAE_03678 1.31e-102 ybaK - - S - - - Protein of unknown function (DUF2521)
MLFELBAE_03679 1.98e-173 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
MLFELBAE_03680 9e-254 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MLFELBAE_03681 6.81e-103 gerD - - - ko:K06294 - ko00000 -
MLFELBAE_03682 1.25e-134 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
MLFELBAE_03683 2.6e-182 pdaB - - G - - - Polysaccharide deacetylase
MLFELBAE_03684 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
MLFELBAE_03685 5.32e-242 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MLFELBAE_03686 6.1e-40 yazB - - K - - - transcriptional
MLFELBAE_03687 2.35e-117 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MLFELBAE_03688 4.62e-81 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MLFELBAE_03689 2.24e-203 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MLFELBAE_03690 1.71e-207 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
MLFELBAE_03691 5.35e-139 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
MLFELBAE_03692 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MLFELBAE_03693 8.88e-217 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
MLFELBAE_03694 3.55e-201 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
MLFELBAE_03695 3.19e-206 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MLFELBAE_03696 6.64e-187 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MLFELBAE_03697 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MLFELBAE_03698 1.05e-119 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
MLFELBAE_03699 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MLFELBAE_03700 1.57e-234 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
MLFELBAE_03701 3.79e-166 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
MLFELBAE_03702 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
MLFELBAE_03705 3.54e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
MLFELBAE_03706 1.2e-74 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
MLFELBAE_03707 3.37e-134 yabQ - - S - - - spore cortex biosynthesis protein
MLFELBAE_03708 5.47e-66 yabP - - S - - - Sporulation protein YabP
MLFELBAE_03709 8.51e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
MLFELBAE_03710 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
MLFELBAE_03711 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MLFELBAE_03712 8.02e-119 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
MLFELBAE_03713 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MLFELBAE_03714 1.1e-54 yabK - - S - - - Peptide ABC transporter permease
MLFELBAE_03715 7.09e-136 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MLFELBAE_03716 2.52e-136 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MLFELBAE_03717 1.22e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MLFELBAE_03718 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MLFELBAE_03719 4.23e-64 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
MLFELBAE_03720 7.5e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
MLFELBAE_03721 5.67e-197 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
MLFELBAE_03722 7.83e-206 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MLFELBAE_03723 7.31e-38 sspF - - S ko:K06423 - ko00000 DNA topological change
MLFELBAE_03724 5.32e-53 veg - - S - - - protein conserved in bacteria
MLFELBAE_03725 2.85e-209 yabG - - S ko:K06436 - ko00000 peptidase
MLFELBAE_03726 8.41e-203 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MLFELBAE_03727 7.62e-126 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MLFELBAE_03728 2.49e-310 yabE - - T - - - protein conserved in bacteria
MLFELBAE_03729 1.24e-183 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
MLFELBAE_03730 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MLFELBAE_03731 6.14e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
MLFELBAE_03732 8.18e-210 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MLFELBAE_03733 1.41e-63 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
MLFELBAE_03734 3.99e-178 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
MLFELBAE_03735 3.08e-56 yabA - - L - - - Involved in initiation control of chromosome replication
MLFELBAE_03736 9e-189 yaaT - - S - - - stage 0 sporulation protein
MLFELBAE_03737 3.29e-234 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
MLFELBAE_03738 2.98e-94 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
MLFELBAE_03739 5.03e-73 yaaQ - - S - - - protein conserved in bacteria
MLFELBAE_03740 7.75e-145 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MLFELBAE_03741 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
MLFELBAE_03742 8.46e-245 yaaN - - P - - - Belongs to the TelA family
MLFELBAE_03743 5.91e-136 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
MLFELBAE_03744 4.46e-42 csfB - - S - - - Inhibitor of sigma-G Gin
MLFELBAE_03755 0.0 - - - C - - - Na+/H+ antiporter family
MLFELBAE_03756 4.02e-171 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
MLFELBAE_03757 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MLFELBAE_03758 0.0 ygaK - - C - - - Berberine and berberine like
MLFELBAE_03760 4.47e-291 oppA5 - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 PFAM extracellular solute-binding protein family 5
MLFELBAE_03761 2.02e-179 - - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MLFELBAE_03762 4.37e-162 - - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLFELBAE_03763 7.73e-170 oppD3 - - P ko:K02031 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MLFELBAE_03764 3.29e-168 oppF9 - - E ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MLFELBAE_03765 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
MLFELBAE_03766 5.69e-235 - - - S ko:K07045 - ko00000 Amidohydrolase
MLFELBAE_03767 4.5e-180 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
MLFELBAE_03768 2.13e-230 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
MLFELBAE_03769 8.27e-186 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
MLFELBAE_03770 3e-273 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
MLFELBAE_03771 1.38e-54 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MLFELBAE_03772 5.25e-106 ygaO - - - - - - -
MLFELBAE_03773 9.41e-32 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
MLFELBAE_03775 1.58e-146 yhzB - - S - - - B3/4 domain
MLFELBAE_03776 2.42e-286 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MLFELBAE_03777 2.13e-226 yhbB - - S - - - Putative amidase domain
MLFELBAE_03778 2.8e-111 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MLFELBAE_03779 1.39e-140 yhbD - - K - - - Protein of unknown function (DUF4004)
MLFELBAE_03780 2.81e-85 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
MLFELBAE_03781 2.02e-94 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
MLFELBAE_03782 1.23e-07 - - - - - - - -
MLFELBAE_03783 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
MLFELBAE_03784 4.34e-281 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
MLFELBAE_03785 1.19e-97 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
MLFELBAE_03786 1.54e-132 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
MLFELBAE_03787 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
MLFELBAE_03788 9.09e-129 wrbA 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
MLFELBAE_03789 1.41e-72 yhcC - - - - - - -
MLFELBAE_03790 2.33e-66 - - - - - - - -
MLFELBAE_03791 4.71e-81 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
MLFELBAE_03792 1.46e-161 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MLFELBAE_03793 1.93e-214 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MLFELBAE_03794 2.13e-207 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MLFELBAE_03795 7.28e-42 cspB - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
MLFELBAE_03796 3.54e-191 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
MLFELBAE_03797 1.94e-248 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
MLFELBAE_03798 1.29e-293 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MLFELBAE_03799 1.9e-79 yhcM - - - - - - -
MLFELBAE_03800 2.69e-122 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MLFELBAE_03801 3.2e-205 yhcP - - - - - - -
MLFELBAE_03802 6.07e-149 yhcQ - - M - - - Spore coat protein
MLFELBAE_03803 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MLFELBAE_03804 4.55e-137 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
MLFELBAE_03805 2.18e-214 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
MLFELBAE_03806 1.88e-92 yhcU - - S - - - Family of unknown function (DUF5365)
MLFELBAE_03807 6.12e-91 yhcV - - S - - - COG0517 FOG CBS domain
MLFELBAE_03808 3.41e-161 yhcW - - S ko:K07025 - ko00000 hydrolase
MLFELBAE_03809 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MLFELBAE_03810 1.16e-171 puuD - - S ko:K07010 - ko00000,ko01002 Peptidase C26
MLFELBAE_03811 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
MLFELBAE_03812 7.5e-127 ynaD - - J - - - Acetyltransferase (GNAT) domain
MLFELBAE_03813 6.07e-192 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
MLFELBAE_03814 2.68e-248 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
MLFELBAE_03815 3.34e-269 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
MLFELBAE_03816 4.57e-287 fabF_1 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MLFELBAE_03817 1.84e-199 - - - K - - - Helix-turn-helix XRE-family like proteins
MLFELBAE_03818 5.2e-157 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
MLFELBAE_03819 3.58e-107 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
MLFELBAE_03820 6.15e-195 bltR - - K - - - helix_turn_helix, mercury resistance
MLFELBAE_03821 8.55e-190 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MLFELBAE_03822 1.92e-146 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
MLFELBAE_03823 4.68e-188 - - - Q - - - ubiE/COQ5 methyltransferase family
MLFELBAE_03824 1.2e-211 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
MLFELBAE_03825 1.61e-154 ydhC - - K - - - FCD
MLFELBAE_03826 7.91e-290 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MLFELBAE_03829 0.0 pbpE - - V - - - Beta-lactamase
MLFELBAE_03831 2.49e-127 ydhK - - M - - - Protein of unknown function (DUF1541)
MLFELBAE_03832 2.14e-245 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
MLFELBAE_03833 2.06e-171 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
MLFELBAE_03834 3.25e-154 - - - K ko:K05799 - ko00000,ko03000 FCD
MLFELBAE_03835 1.23e-276 yycB1 - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
MLFELBAE_03836 1.48e-65 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
MLFELBAE_03837 4.48e-67 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
MLFELBAE_03838 3.63e-136 yvdT_1 - - K - - - Transcriptional regulator
MLFELBAE_03839 0.0 ybeC - - E - - - amino acid
MLFELBAE_03840 5.15e-213 ydhU - - P ko:K07217 - ko00000 Catalase
MLFELBAE_03841 2.06e-112 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
MLFELBAE_03842 2.83e-237 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
MLFELBAE_03843 0.0 iolT - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MLFELBAE_03846 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
MLFELBAE_03847 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
MLFELBAE_03848 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
MLFELBAE_03849 1.38e-113 yvgO - - - - - - -
MLFELBAE_03850 7.23e-200 yvgN - - S - - - reductase
MLFELBAE_03851 7.22e-262 sagI - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
MLFELBAE_03852 2.11e-250 sagH - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
MLFELBAE_03853 8.23e-219 sagG - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
MLFELBAE_03854 1.17e-250 - - - T - - - Histidine kinase
MLFELBAE_03855 4.37e-146 yfiK - - K - - - Regulator
MLFELBAE_03856 1.92e-123 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
MLFELBAE_03857 1.6e-177 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
MLFELBAE_03858 1.41e-213 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
MLFELBAE_03859 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
MLFELBAE_03860 1.01e-110 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
MLFELBAE_03861 1.29e-20 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
MLFELBAE_03862 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
MLFELBAE_03863 3.57e-159 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MLFELBAE_03864 2.21e-228 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MLFELBAE_03865 1.56e-236 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLFELBAE_03866 1.37e-225 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLFELBAE_03867 1.14e-187 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MLFELBAE_03868 6.44e-50 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
MLFELBAE_03869 5.4e-43 yaaL - - S - - - Protein of unknown function (DUF2508)
MLFELBAE_03870 8.53e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MLFELBAE_03871 2.41e-52 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MLFELBAE_03872 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MLFELBAE_03873 2.89e-110 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MLFELBAE_03874 5.85e-128 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
MLFELBAE_03875 1.23e-278 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
MLFELBAE_03876 4.71e-148 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
MLFELBAE_03877 7.51e-159 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
MLFELBAE_03879 2.94e-261 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
MLFELBAE_03880 6.46e-285 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MLFELBAE_03881 1.66e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MLFELBAE_03882 1.29e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MLFELBAE_03883 0.0 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MLFELBAE_03884 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MLFELBAE_03885 1.37e-232 yaaC - - S - - - YaaC-like Protein
MLFELBAE_03886 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
MLFELBAE_03901 4.69e-172 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
MLFELBAE_03910 2.12e-33 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)