ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
MHPNILHJ_00011 0.0 - - - C - - - Na+/H+ antiporter family
MHPNILHJ_00012 2.04e-159 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
MHPNILHJ_00013 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MHPNILHJ_00014 3.15e-313 ygaK - - C - - - Berberine and berberine like
MHPNILHJ_00016 1.69e-291 oppA5 - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 PFAM extracellular solute-binding protein family 5
MHPNILHJ_00017 2.33e-185 - - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MHPNILHJ_00018 6.2e-162 - - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHPNILHJ_00019 5.45e-170 oppD3 - - P ko:K02031 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MHPNILHJ_00020 5.17e-165 oppF9 - - E ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MHPNILHJ_00021 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
MHPNILHJ_00022 2.39e-227 - - - S ko:K07045 - ko00000 Amidohydrolase
MHPNILHJ_00023 1.02e-176 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
MHPNILHJ_00024 2.34e-218 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
MHPNILHJ_00025 6.5e-183 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
MHPNILHJ_00026 8.25e-271 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
MHPNILHJ_00028 1.62e-53 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MHPNILHJ_00029 2.4e-102 ygaO - - - - - - -
MHPNILHJ_00030 5.45e-31 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
MHPNILHJ_00032 1.34e-138 yhzB - - S - - - B3/4 domain
MHPNILHJ_00033 2.14e-280 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MHPNILHJ_00034 8.37e-216 yhbB - - S - - - Putative amidase domain
MHPNILHJ_00035 2.31e-110 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MHPNILHJ_00036 3.35e-132 yhbD - - K - - - Protein of unknown function (DUF4004)
MHPNILHJ_00037 2.51e-76 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
MHPNILHJ_00038 7.48e-85 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
MHPNILHJ_00039 1.23e-07 - - - - - - - -
MHPNILHJ_00040 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
MHPNILHJ_00041 2.12e-276 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
MHPNILHJ_00042 5.43e-94 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
MHPNILHJ_00043 2.98e-130 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
MHPNILHJ_00044 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
MHPNILHJ_00045 2.61e-128 wrbA 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
MHPNILHJ_00046 1.03e-65 yhcC - - - - - - -
MHPNILHJ_00047 7.54e-65 - - - - - - - -
MHPNILHJ_00048 8.78e-77 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
MHPNILHJ_00049 3.78e-148 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHPNILHJ_00050 3.74e-212 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHPNILHJ_00051 1.87e-201 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MHPNILHJ_00052 7.28e-42 cspB - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
MHPNILHJ_00053 2.09e-165 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
MHPNILHJ_00054 2.76e-230 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
MHPNILHJ_00055 1.01e-290 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MHPNILHJ_00056 9.03e-50 - 3.5.1.6, 3.5.1.87 - E ko:K06016 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
MHPNILHJ_00057 6.23e-61 yhcM - - - - - - -
MHPNILHJ_00058 2.12e-117 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MHPNILHJ_00059 6.62e-198 yhcP - - - - - - -
MHPNILHJ_00060 4.1e-147 yhcQ - - M - - - Spore coat protein
MHPNILHJ_00061 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MHPNILHJ_00062 3.17e-128 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
MHPNILHJ_00063 2.24e-207 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
MHPNILHJ_00064 1.88e-83 yhcU - - S - - - Family of unknown function (DUF5365)
MHPNILHJ_00065 5.88e-89 yhcV - - S - - - COG0517 FOG CBS domain
MHPNILHJ_00066 1.33e-158 yhcW - - S ko:K07025 - ko00000 hydrolase
MHPNILHJ_00067 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MHPNILHJ_00068 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MHPNILHJ_00069 3.35e-131 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MHPNILHJ_00070 2.6e-195 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MHPNILHJ_00071 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MHPNILHJ_00072 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MHPNILHJ_00073 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
MHPNILHJ_00074 3.71e-245 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
MHPNILHJ_00075 7.97e-139 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MHPNILHJ_00076 3.01e-110 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
MHPNILHJ_00077 1.16e-51 yhdB - - S - - - YhdB-like protein
MHPNILHJ_00078 2.33e-68 yhdC - - S - - - Protein of unknown function (DUF3889)
MHPNILHJ_00079 1.32e-279 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
MHPNILHJ_00080 6.05e-93 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
MHPNILHJ_00081 5.72e-314 ygxB - - M - - - Conserved TM helix
MHPNILHJ_00082 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
MHPNILHJ_00083 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
MHPNILHJ_00084 1.32e-165 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
MHPNILHJ_00085 3.42e-201 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
MHPNILHJ_00086 8.91e-250 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
MHPNILHJ_00087 2.41e-200 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHPNILHJ_00088 1.1e-311 yhdG - - E ko:K03294 - ko00000 amino acid
MHPNILHJ_00089 4.63e-264 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MHPNILHJ_00090 8.62e-59 yhdK - - S - - - Sigma-M inhibitor protein
MHPNILHJ_00091 2.03e-249 yhdL - - S - - - Sigma factor regulator N-terminal
MHPNILHJ_00092 4.6e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MHPNILHJ_00093 4.04e-136 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MHPNILHJ_00094 2.66e-305 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
MHPNILHJ_00095 2.3e-91 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
MHPNILHJ_00096 2.3e-276 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
MHPNILHJ_00097 7.35e-290 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MHPNILHJ_00098 5.48e-314 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
MHPNILHJ_00099 1.68e-69 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MHPNILHJ_00100 4.22e-71 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MHPNILHJ_00101 3.77e-158 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
MHPNILHJ_00102 1.45e-08 yhdX - - S - - - Uncharacterized protein YhdX
MHPNILHJ_00103 1.54e-251 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
MHPNILHJ_00104 7.42e-174 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
MHPNILHJ_00105 3.96e-191 nodB1 - - G - - - deacetylase
MHPNILHJ_00106 6.34e-193 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
MHPNILHJ_00107 4.2e-106 pksA - - K - - - Transcriptional regulator
MHPNILHJ_00108 1.66e-118 ymcC - - S - - - Membrane
MHPNILHJ_00109 2.39e-108 - - - T - - - universal stress protein
MHPNILHJ_00110 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
MHPNILHJ_00111 0.0 yheH - - V ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
MHPNILHJ_00112 4.78e-127 yheG - - GM - - - NAD(P)H-binding
MHPNILHJ_00114 1.91e-38 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
MHPNILHJ_00115 2.12e-49 yheE - - S - - - Family of unknown function (DUF5342)
MHPNILHJ_00116 5.52e-316 yheD - - HJ - - - YheC/D like ATP-grasp
MHPNILHJ_00117 2.7e-257 yheC - - HJ - - - YheC/D like ATP-grasp
MHPNILHJ_00118 3.13e-254 yheB - - S - - - Belongs to the UPF0754 family
MHPNILHJ_00119 2.72e-69 yheA - - S - - - Belongs to the UPF0342 family
MHPNILHJ_00120 2.49e-197 yhaX - - S - - - haloacid dehalogenase-like hydrolase
MHPNILHJ_00121 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
MHPNILHJ_00122 1.48e-311 - 1.14.13.59 - Q ko:K03897 ko00310,ko01120,map00310,map01120 ko00000,ko00001,ko01000 L-lysine 6-monooxygenase (NADPH-requiring)
MHPNILHJ_00123 7.44e-262 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
MHPNILHJ_00124 1.53e-112 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
MHPNILHJ_00126 1.87e-171 yhaR - - I - - - enoyl-CoA hydratase
MHPNILHJ_00127 1.21e-20 - - - S - - - YhzD-like protein
MHPNILHJ_00128 3.45e-209 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHPNILHJ_00129 2.67e-274 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
MHPNILHJ_00130 3.8e-293 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
MHPNILHJ_00131 0.0 yhaN - - L - - - AAA domain
MHPNILHJ_00132 5.61e-223 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
MHPNILHJ_00133 8.23e-43 yhaL - - S - - - Sporulation protein YhaL
MHPNILHJ_00134 7.87e-183 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MHPNILHJ_00135 4.32e-122 yhaK - - S - - - Putative zincin peptidase
MHPNILHJ_00136 1.2e-72 yhaI - - S - - - Protein of unknown function (DUF1878)
MHPNILHJ_00137 4.54e-144 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
MHPNILHJ_00138 1.58e-53 yhaH - - S - - - YtxH-like protein
MHPNILHJ_00139 2.55e-24 - - - - - - - -
MHPNILHJ_00140 1.12e-97 trpP - - S - - - Tryptophan transporter TrpP
MHPNILHJ_00141 1.49e-252 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MHPNILHJ_00142 5.82e-105 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
MHPNILHJ_00143 2.13e-173 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
MHPNILHJ_00144 3.4e-276 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
MHPNILHJ_00145 9.96e-152 ecsC - - S - - - EcsC protein family
MHPNILHJ_00146 1.68e-274 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
MHPNILHJ_00147 1.65e-303 yhfA - - C - - - membrane
MHPNILHJ_00148 2.98e-115 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
MHPNILHJ_00149 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
MHPNILHJ_00150 9.19e-253 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MHPNILHJ_00151 3.4e-227 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
MHPNILHJ_00152 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MHPNILHJ_00153 5.15e-130 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
MHPNILHJ_00154 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
MHPNILHJ_00155 2.04e-226 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MHPNILHJ_00157 1.66e-247 yhfE - - G - - - peptidase M42
MHPNILHJ_00158 3.75e-286 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MHPNILHJ_00159 2.4e-173 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
MHPNILHJ_00160 1.07e-240 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
MHPNILHJ_00161 3.92e-137 yhfK - - GM - - - NmrA-like family
MHPNILHJ_00162 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
MHPNILHJ_00163 9.31e-84 yhfM - - - - - - -
MHPNILHJ_00164 1.33e-293 yhfN - - O - - - Peptidase M48
MHPNILHJ_00165 1.24e-258 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MHPNILHJ_00166 1.78e-163 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
MHPNILHJ_00167 1.59e-129 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
MHPNILHJ_00168 8.49e-245 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
MHPNILHJ_00169 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
MHPNILHJ_00170 2.32e-110 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
MHPNILHJ_00171 1.71e-271 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
MHPNILHJ_00172 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
MHPNILHJ_00173 2.73e-204 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHPNILHJ_00174 5.49e-42 yhzC - - S - - - IDEAL
MHPNILHJ_00175 2.19e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
MHPNILHJ_00176 4.21e-74 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
MHPNILHJ_00177 1.28e-213 - - - S - - - Acetyltransferase, GNAT family
MHPNILHJ_00178 1.53e-156 yrpD - - S - - - Domain of unknown function, YrpD
MHPNILHJ_00179 7.11e-57 yhjA - - S - - - Excalibur calcium-binding domain
MHPNILHJ_00180 2.64e-63 - - - S - - - Belongs to the UPF0145 family
MHPNILHJ_00181 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MHPNILHJ_00182 5.59e-37 yhjC - - S - - - Protein of unknown function (DUF3311)
MHPNILHJ_00183 2.3e-76 yhjD - - - - - - -
MHPNILHJ_00184 8.02e-136 yhjE - - S - - - SNARE associated Golgi protein
MHPNILHJ_00185 1.3e-116 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MHPNILHJ_00186 0.0 yhjG - - CH - - - FAD binding domain
MHPNILHJ_00187 9.88e-120 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
MHPNILHJ_00188 2.03e-254 yhjN - - S ko:K07120 - ko00000 membrane
MHPNILHJ_00189 1.56e-260 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
MHPNILHJ_00190 1.24e-138 - - - K - - - QacR-like protein, C-terminal region
MHPNILHJ_00191 3.47e-108 yhjR - - S - - - Rubrerythrin
MHPNILHJ_00192 8.81e-152 ydfS - - S - - - Protein of unknown function (DUF421)
MHPNILHJ_00193 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
MHPNILHJ_00194 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
MHPNILHJ_00195 7.47e-280 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MHPNILHJ_00196 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
MHPNILHJ_00197 3.36e-66 yisB - - V - - - COG1403 Restriction endonuclease
MHPNILHJ_00198 5.49e-42 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
MHPNILHJ_00199 1.43e-78 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
MHPNILHJ_00200 1.44e-31 gerPD - - S ko:K06302 - ko00000 Spore germination protein
MHPNILHJ_00201 3.28e-104 gerPC - - S ko:K06301 - ko00000 Spore germination protein
MHPNILHJ_00202 1.01e-44 gerPB - - S ko:K06300 - ko00000 cell differentiation
MHPNILHJ_00203 1.28e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
MHPNILHJ_00204 2.45e-13 yisI - - S - - - Spo0E like sporulation regulatory protein
MHPNILHJ_00205 2.25e-211 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
MHPNILHJ_00206 4.48e-78 yisL - - S - - - UPF0344 protein
MHPNILHJ_00207 0.0 wprA - - O ko:K13274 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MHPNILHJ_00208 5.25e-115 yisN - - S - - - Protein of unknown function (DUF2777)
MHPNILHJ_00209 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
MHPNILHJ_00210 6.09e-150 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
MHPNILHJ_00211 1.69e-307 yisQ - - V - - - Mate efflux family protein
MHPNILHJ_00212 1.77e-201 yisR - - K - - - Transcriptional regulator
MHPNILHJ_00213 3.87e-179 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
MHPNILHJ_00214 2.32e-195 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
MHPNILHJ_00215 3.26e-100 yisT - - S - - - DinB family
MHPNILHJ_00216 8.48e-96 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
MHPNILHJ_00217 1.49e-233 yisV - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MHPNILHJ_00218 6.78e-84 yisX - - S - - - Pentapeptide repeats (9 copies)
MHPNILHJ_00219 6.78e-100 - - - S - - - Acetyltransferase (GNAT) domain
MHPNILHJ_00220 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
MHPNILHJ_00221 7.44e-78 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
MHPNILHJ_00222 3.3e-199 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
MHPNILHJ_00223 2.3e-186 - - - S ko:K07335 - ko00000 ABC transporter substrate-binding protein PnrA-like
MHPNILHJ_00224 1.06e-288 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
MHPNILHJ_00225 8.38e-297 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
MHPNILHJ_00227 3.42e-197 yitS - - S - - - protein conserved in bacteria
MHPNILHJ_00228 4.62e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
MHPNILHJ_00229 3.05e-104 ipi - - S - - - Intracellular proteinase inhibitor
MHPNILHJ_00230 4.3e-36 - - - S - - - Protein of unknown function (DUF3813)
MHPNILHJ_00231 1.49e-11 - - - - - - - -
MHPNILHJ_00232 3.84e-192 - 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
MHPNILHJ_00233 1.62e-181 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
MHPNILHJ_00234 3.26e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
MHPNILHJ_00235 3.29e-92 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
MHPNILHJ_00236 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
MHPNILHJ_00237 4.44e-117 yitZ - - G - - - Major Facilitator Superfamily
MHPNILHJ_00238 4.41e-247 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MHPNILHJ_00239 4.35e-282 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MHPNILHJ_00240 3.58e-166 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
MHPNILHJ_00241 5.32e-266 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
MHPNILHJ_00242 4.59e-248 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
MHPNILHJ_00243 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
MHPNILHJ_00244 1.78e-220 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MHPNILHJ_00245 2.07e-38 yjzC - - S - - - YjzC-like protein
MHPNILHJ_00246 3.71e-31 yjzD - - S - - - Protein of unknown function (DUF2929)
MHPNILHJ_00247 6.59e-171 yjaU - - I - - - carboxylic ester hydrolase activity
MHPNILHJ_00248 7.04e-127 yjaV - - - - - - -
MHPNILHJ_00249 8.66e-209 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
MHPNILHJ_00250 3.74e-36 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
MHPNILHJ_00251 1.46e-37 yjzB - - - - - - -
MHPNILHJ_00252 1.26e-218 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MHPNILHJ_00253 1.24e-296 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MHPNILHJ_00254 4.99e-179 yjaZ - - O - - - Zn-dependent protease
MHPNILHJ_00255 4.64e-229 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MHPNILHJ_00256 1.1e-232 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MHPNILHJ_00257 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
MHPNILHJ_00258 8.55e-219 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHPNILHJ_00259 7.81e-209 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHPNILHJ_00260 5.28e-189 yjbA - - S - - - Belongs to the UPF0736 family
MHPNILHJ_00261 8.74e-235 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
MHPNILHJ_00262 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MHPNILHJ_00263 2.08e-212 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHPNILHJ_00264 1.46e-209 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHPNILHJ_00265 1.96e-252 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MHPNILHJ_00266 1e-216 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MHPNILHJ_00267 3.04e-280 - - - S - - - Putative glycosyl hydrolase domain
MHPNILHJ_00268 1.04e-130 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MHPNILHJ_00269 2.47e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MHPNILHJ_00270 2.28e-140 yjbE - - P - - - Integral membrane protein TerC family
MHPNILHJ_00271 2.3e-148 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MHPNILHJ_00272 1.14e-256 coiA - - S ko:K06198 - ko00000 Competence protein
MHPNILHJ_00273 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
MHPNILHJ_00274 3.14e-27 - - - - - - - -
MHPNILHJ_00275 9.23e-215 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
MHPNILHJ_00276 6.79e-91 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
MHPNILHJ_00277 1.15e-138 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MHPNILHJ_00278 8.1e-118 yjbK - - S - - - protein conserved in bacteria
MHPNILHJ_00279 3.37e-79 yjbL - - S - - - Belongs to the UPF0738 family
MHPNILHJ_00280 3.67e-138 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
MHPNILHJ_00281 6.92e-193 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MHPNILHJ_00282 2.7e-201 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
MHPNILHJ_00283 1.1e-176 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
MHPNILHJ_00284 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MHPNILHJ_00285 2.06e-170 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MHPNILHJ_00286 2.91e-132 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
MHPNILHJ_00287 8.33e-255 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
MHPNILHJ_00288 5.3e-40 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 Thiamine biosynthesis
MHPNILHJ_00289 1.81e-173 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
MHPNILHJ_00290 7.09e-228 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MHPNILHJ_00291 2.99e-180 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
MHPNILHJ_00292 1.38e-179 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
MHPNILHJ_00293 2.47e-100 yjbX - - S - - - Spore coat protein
MHPNILHJ_00294 3.35e-105 cotZ - - S ko:K06344 - ko00000 Spore coat protein
MHPNILHJ_00295 1.75e-120 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
MHPNILHJ_00296 3.55e-98 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
MHPNILHJ_00297 1.02e-36 cotW - - - ko:K06341 - ko00000 -
MHPNILHJ_00298 4.61e-69 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
MHPNILHJ_00299 1.69e-72 yjcA - - S - - - Protein of unknown function (DUF1360)
MHPNILHJ_00302 3.58e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
MHPNILHJ_00303 1.05e-50 spoVIF - - S - - - Stage VI sporulation protein F
MHPNILHJ_00304 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
MHPNILHJ_00305 1.62e-44 - - - - - - - -
MHPNILHJ_00306 6.53e-167 blm 3.5.2.6 - S ko:K17837 ko01501,map01501 ko00000,ko00001,ko01000 Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
MHPNILHJ_00307 2e-154 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
MHPNILHJ_00308 1.09e-165 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
MHPNILHJ_00309 1.19e-45 - - - K - - - SpoVT / AbrB like domain
MHPNILHJ_00310 6.83e-94 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MHPNILHJ_00311 6.7e-119 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
MHPNILHJ_00312 1.79e-157 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
MHPNILHJ_00313 2.09e-266 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
MHPNILHJ_00314 5.84e-273 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
MHPNILHJ_00316 7.48e-225 int7 - - L - - - Belongs to the 'phage' integrase family
MHPNILHJ_00317 3.5e-63 xkdA - - E - - - IrrE N-terminal-like domain
MHPNILHJ_00318 1.53e-96 - - - S - - - Bacterial PH domain
MHPNILHJ_00319 5.32e-112 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
MHPNILHJ_00320 4.44e-25 - - - K - - - Helix-turn-helix XRE-family like proteins
MHPNILHJ_00321 7.04e-08 - - - K - - - Helix-turn-helix domain
MHPNILHJ_00322 5.71e-22 - - - S - - - Helix-turn-helix domain
MHPNILHJ_00323 5.41e-109 - - - - - - - -
MHPNILHJ_00327 3.11e-127 - - - - - - - -
MHPNILHJ_00328 2.07e-86 pi112 - - L - - - PDDEXK-like domain of unknown function (DUF3799)
MHPNILHJ_00330 1.22e-97 yqaL - - L - - - DnaD domain protein
MHPNILHJ_00331 1.41e-83 yqaM - - L - - - IstB-like ATP binding protein
MHPNILHJ_00333 1.07e-76 rusA - - L - - - Endodeoxyribonuclease RusA
MHPNILHJ_00335 1.16e-23 yqaO - - S - - - Phage-like element PBSX protein XtrA
MHPNILHJ_00338 1.81e-33 - - - - - - - -
MHPNILHJ_00340 5.5e-201 - - - EH - - - sulfate reduction
MHPNILHJ_00341 6.17e-85 - - - - - - - -
MHPNILHJ_00344 3.12e-61 - - - - - - - -
MHPNILHJ_00346 3.08e-59 - 4.6.1.1 - T ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 ko00000,ko00001,ko00002,ko01000 Pfam Adenylate and Guanylate cyclase catalytic domain
MHPNILHJ_00350 4.05e-61 - - - L - - - Transposase
MHPNILHJ_00353 6.46e-104 yqaS - - L - - - DNA packaging
MHPNILHJ_00354 2.46e-233 - - - S - - - Terminase-like family
MHPNILHJ_00355 2.48e-193 - - - S - - - Phage portal protein, SPP1 Gp6-like
MHPNILHJ_00357 9.22e-69 - - - S - - - Domain of unknown function (DUF4355)
MHPNILHJ_00358 8.89e-154 - - - S - - - P22 coat protein - gene protein 5
MHPNILHJ_00360 1.74e-40 - - - S - - - Phage Mu protein F like protein
MHPNILHJ_00362 1.21e-61 - - - - - - - -
MHPNILHJ_00364 1.47e-41 - - - - - - - -
MHPNILHJ_00365 1.78e-130 - - - S - - - Protein of unknown function (DUF3383)
MHPNILHJ_00366 2.25e-46 - - - - - - - -
MHPNILHJ_00367 1.65e-19 - - - - - - - -
MHPNILHJ_00368 1.88e-181 - - - N - - - phage tail tape measure protein
MHPNILHJ_00369 9.44e-55 - - - M - - - LysM domain
MHPNILHJ_00370 5.45e-31 - - - - - - - -
MHPNILHJ_00371 2.04e-108 - - - - - - - -
MHPNILHJ_00372 6.47e-35 - - - - - - - -
MHPNILHJ_00373 4.16e-33 - - - S - - - Protein of unknown function (DUF2634)
MHPNILHJ_00374 4.86e-126 - - - S - - - homolog of phage Mu protein gp47
MHPNILHJ_00375 4.28e-79 - - - - - - - -
MHPNILHJ_00376 4.93e-71 - - - - - - - -
MHPNILHJ_00378 1.64e-24 xkdX - - - - - - -
MHPNILHJ_00379 1.19e-40 xhlA - - S - - - Haemolysin XhlA
MHPNILHJ_00380 2.95e-37 xhlB - - S - - - SPP1 phage holin
MHPNILHJ_00381 1.07e-81 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 Ami_2
MHPNILHJ_00383 3.21e-74 - - - M - - - NLP P60 protein
MHPNILHJ_00384 6.76e-29 - - - K - - - Helix-turn-helix domain
MHPNILHJ_00385 8.37e-39 - - - S - - - SMI1-KNR4 cell-wall
MHPNILHJ_00386 1.63e-241 - - - M - - - nucleic acid phosphodiester bond hydrolysis
MHPNILHJ_00390 2.89e-73 - - - - - - - -
MHPNILHJ_00391 2.31e-90 - - - S - - - Bacterial EndoU nuclease
MHPNILHJ_00392 1.06e-42 - - - - - - - -
MHPNILHJ_00393 1.86e-116 yokH - - G - - - SMI1 / KNR4 family
MHPNILHJ_00394 1.61e-128 - 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 2-dehydropantoate 2-reductase
MHPNILHJ_00395 2.21e-28 yokK - - S - - - SMI1 / KNR4 family
MHPNILHJ_00396 9.5e-81 - - - H - - - Acetyltransferase (GNAT) domain
MHPNILHJ_00398 7.99e-240 - - - K - - - Psort location Cytoplasmic, score
MHPNILHJ_00399 0.0 - - - K - - - Psort location Cytoplasmic, score
MHPNILHJ_00400 9.18e-49 - - - S - - - YolD-like protein
MHPNILHJ_00401 2.46e-57 dinB2 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MHPNILHJ_00402 4.74e-38 - - - S - - - Bacillus cereus group antimicrobial protein
MHPNILHJ_00406 6.15e-32 - - - N - - - Kelch motif
MHPNILHJ_00408 1.32e-196 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
MHPNILHJ_00409 5.19e-60 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
MHPNILHJ_00410 1.35e-302 yfjF - - EGP - - - Belongs to the major facilitator superfamily
MHPNILHJ_00411 1.09e-99 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MHPNILHJ_00412 7.71e-277 yvfO 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
MHPNILHJ_00413 0.0 lacE 2.7.1.207 - G ko:K02761,ko:K02787,ko:K02788 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHPNILHJ_00414 3.63e-66 celC 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MHPNILHJ_00415 0.0 lacG 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MHPNILHJ_00416 1.39e-177 yulB - - K ko:K02530 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
MHPNILHJ_00417 1.67e-151 - - - S - - - Haloacid dehalogenase-like hydrolase
MHPNILHJ_00418 3.81e-45 - - - - - - - -
MHPNILHJ_00419 4.16e-69 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MHPNILHJ_00420 2.77e-133 - - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
MHPNILHJ_00422 1.07e-28 yjfB - - S - - - Putative motility protein
MHPNILHJ_00423 6.25e-83 yjgA - - T - - - Protein of unknown function (DUF2809)
MHPNILHJ_00424 4.05e-122 yjgB - - S - - - Domain of unknown function (DUF4309)
MHPNILHJ_00425 0.0 - 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
MHPNILHJ_00426 5.56e-111 yjgD - - S - - - Protein of unknown function (DUF1641)
MHPNILHJ_00427 7.68e-274 yjiB 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
MHPNILHJ_00428 3.96e-275 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MHPNILHJ_00429 1.73e-40 - - - - - - - -
MHPNILHJ_00430 1.44e-180 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
MHPNILHJ_00431 3.47e-150 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
MHPNILHJ_00432 2.23e-159 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 Belongs to the ABC transporter superfamily
MHPNILHJ_00433 5.99e-220 yjlA - - EG - - - Putative multidrug resistance efflux transporter
MHPNILHJ_00434 1.47e-110 yjlB - - S - - - Cupin domain
MHPNILHJ_00435 1.7e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
MHPNILHJ_00436 8.37e-278 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
MHPNILHJ_00437 1.75e-98 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
MHPNILHJ_00438 3.99e-232 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
MHPNILHJ_00439 3.18e-203 uxaA 4.2.1.7 - G ko:K01685 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
MHPNILHJ_00440 1.29e-112 - - - T - - - Transcriptional regulatory protein, C terminal
MHPNILHJ_00441 1.84e-166 - - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
MHPNILHJ_00443 7.24e-164 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
MHPNILHJ_00444 9.4e-100 yjoA - - S - - - DinB family
MHPNILHJ_00445 3.13e-274 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
MHPNILHJ_00447 5.72e-213 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
MHPNILHJ_00448 3.19e-79 yjqA - - S - - - Bacterial PH domain
MHPNILHJ_00449 2.69e-128 yjqB - - S - - - phage-related replication protein
MHPNILHJ_00450 2.86e-139 xkdA - - E - - - IrrE N-terminal-like domain
MHPNILHJ_00451 1.27e-72 xre - - K - - - Helix-turn-helix XRE-family like proteins
MHPNILHJ_00453 2.39e-184 xkdC - - L - - - Bacterial dnaA protein
MHPNILHJ_00457 3.15e-105 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
MHPNILHJ_00458 3.6e-137 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
MHPNILHJ_00459 3.35e-263 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
MHPNILHJ_00460 1.72e-302 xkdE3 - - S - - - portal protein
MHPNILHJ_00461 8.47e-119 xkdF3 - - L - - - Putative phage serine protease XkdF
MHPNILHJ_00462 3.38e-202 xkdG - - S - - - Phage capsid family
MHPNILHJ_00463 8.84e-61 yqbG - - S - - - Protein of unknown function (DUF3199)
MHPNILHJ_00465 2.41e-77 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
MHPNILHJ_00466 1.82e-75 xkdJ - - - - - - -
MHPNILHJ_00467 3.86e-21 - - - - - - - -
MHPNILHJ_00468 4.44e-285 xkdK - - S - - - Phage tail sheath C-terminal domain
MHPNILHJ_00469 8.21e-97 xkdM - - S - - - Phage tail tube protein
MHPNILHJ_00470 7.28e-96 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
MHPNILHJ_00471 4.33e-27 - - - - - - - -
MHPNILHJ_00472 9.82e-277 xkdO - - L - - - Transglycosylase SLT domain
MHPNILHJ_00473 1.88e-144 xkdP - - S - - - Lysin motif
MHPNILHJ_00474 2.78e-208 xkdQ - - G - - - NLP P60 protein
MHPNILHJ_00475 3.05e-44 xkdR - - S - - - Protein of unknown function (DUF2577)
MHPNILHJ_00476 1.65e-75 xkdS - - S - - - Protein of unknown function (DUF2634)
MHPNILHJ_00477 5.1e-211 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
MHPNILHJ_00478 2.37e-111 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
MHPNILHJ_00479 1.48e-36 - - - - - - - -
MHPNILHJ_00480 2.06e-224 - - - - - - - -
MHPNILHJ_00481 6.09e-58 xkdW - - S - - - XkdW protein
MHPNILHJ_00482 2.74e-23 xkdX - - - - - - -
MHPNILHJ_00483 2.64e-134 xepA - - - - - - -
MHPNILHJ_00484 6.44e-50 xhlA - - S - - - Haemolysin XhlA
MHPNILHJ_00485 5.3e-49 xhlB - - S - - - SPP1 phage holin
MHPNILHJ_00486 4.2e-207 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
MHPNILHJ_00487 2.53e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
MHPNILHJ_00488 1.05e-169 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
MHPNILHJ_00489 2.36e-224 pit - - P ko:K03306 - ko00000 phosphate transporter
MHPNILHJ_00490 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
MHPNILHJ_00491 2.11e-308 steT - - E ko:K03294 - ko00000 amino acid
MHPNILHJ_00492 1.75e-227 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
MHPNILHJ_00493 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MHPNILHJ_00494 3.02e-227 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
MHPNILHJ_00496 2.08e-266 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MHPNILHJ_00497 0.0 yubD - - P - - - Major Facilitator Superfamily
MHPNILHJ_00498 4.18e-198 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
MHPNILHJ_00499 2.68e-202 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHPNILHJ_00500 3.22e-218 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHPNILHJ_00501 1.49e-230 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MHPNILHJ_00502 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MHPNILHJ_00503 8.59e-221 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
MHPNILHJ_00504 2e-244 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
MHPNILHJ_00505 1.74e-198 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MHPNILHJ_00506 1.49e-227 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MHPNILHJ_00507 6.11e-256 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
MHPNILHJ_00508 1.45e-179 ykgA - - E - - - Amidinotransferase
MHPNILHJ_00509 2.16e-120 ykhA - - I - - - Acyl-CoA hydrolase
MHPNILHJ_00510 1.01e-118 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MHPNILHJ_00511 8.24e-64 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
MHPNILHJ_00512 1.22e-64 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
MHPNILHJ_00513 1.03e-211 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
MHPNILHJ_00514 3.28e-257 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MHPNILHJ_00515 1.35e-281 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MHPNILHJ_00516 1.89e-90 ohrA - - O - - - Organic hydroperoxide resistance protein
MHPNILHJ_00517 6.88e-102 ohrR - - K - - - COG1846 Transcriptional regulators
MHPNILHJ_00518 1.3e-90 ohrB - - O - - - Organic hydroperoxide resistance protein
MHPNILHJ_00519 1.46e-70 - - - D - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MHPNILHJ_00521 2.15e-260 - - - M - - - Glycosyl transferase family 2
MHPNILHJ_00522 8.96e-151 - - - K - - - Collagen triple helix repeat
MHPNILHJ_00523 3.68e-258 - - - EGP ko:K05820 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
MHPNILHJ_00524 7.17e-152 nsr - - T - - - COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
MHPNILHJ_00525 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MHPNILHJ_00526 2.76e-221 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MHPNILHJ_00527 4.2e-179 yojH - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MHPNILHJ_00528 7.49e-161 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
MHPNILHJ_00529 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MHPNILHJ_00530 3.67e-123 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
MHPNILHJ_00531 4.54e-303 ydhD - - M - - - Glycosyl hydrolase
MHPNILHJ_00533 7.93e-306 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
MHPNILHJ_00534 3.53e-69 tnrA - - K - - - transcriptional
MHPNILHJ_00535 2.24e-23 - - - - - - - -
MHPNILHJ_00536 3.57e-35 ykoL - - - - - - -
MHPNILHJ_00537 3.16e-104 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
MHPNILHJ_00538 2.57e-127 ykoP - - G - - - polysaccharide deacetylase
MHPNILHJ_00539 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
MHPNILHJ_00540 1.82e-197 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MHPNILHJ_00541 0.0 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
MHPNILHJ_00542 1.21e-123 ykoX - - S - - - membrane-associated protein
MHPNILHJ_00543 5.75e-164 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
MHPNILHJ_00544 6.02e-163 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHPNILHJ_00545 3.51e-221 ykrI - - S - - - Anti-sigma factor N-terminus
MHPNILHJ_00546 3.31e-35 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
MHPNILHJ_00547 1.55e-159 ykrK - - S - - - Domain of unknown function (DUF1836)
MHPNILHJ_00548 1.74e-197 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
MHPNILHJ_00549 7.83e-301 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
MHPNILHJ_00550 2.76e-144 - - - S - - - Protein of unknown function (DUF421)
MHPNILHJ_00551 1.37e-26 ykzE - - - - - - -
MHPNILHJ_00552 1.59e-242 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
MHPNILHJ_00553 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MHPNILHJ_00554 9.18e-105 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MHPNILHJ_00556 1.59e-244 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MHPNILHJ_00557 9.79e-278 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
MHPNILHJ_00558 1.03e-175 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MHPNILHJ_00559 1.52e-283 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MHPNILHJ_00560 4.16e-284 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
MHPNILHJ_00561 1.45e-169 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
MHPNILHJ_00562 1.15e-140 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
MHPNILHJ_00563 7.7e-117 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
MHPNILHJ_00565 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
MHPNILHJ_00566 3.34e-101 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
MHPNILHJ_00567 1.14e-160 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
MHPNILHJ_00568 2.96e-176 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
MHPNILHJ_00569 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
MHPNILHJ_00570 6.18e-222 ykvI - - S - - - membrane
MHPNILHJ_00572 1.81e-196 - - - - - - - -
MHPNILHJ_00573 2.72e-162 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MHPNILHJ_00574 2.55e-102 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
MHPNILHJ_00575 1.98e-176 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
MHPNILHJ_00576 2.56e-124 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MHPNILHJ_00577 6.76e-56 ykvR - - S - - - Protein of unknown function (DUF3219)
MHPNILHJ_00578 1.56e-34 ykvS - - S - - - protein conserved in bacteria
MHPNILHJ_00579 8.76e-38 - - - - - - - -
MHPNILHJ_00580 5.23e-136 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
MHPNILHJ_00581 1.16e-300 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MHPNILHJ_00582 6.24e-107 stoA - - CO - - - thiol-disulfide
MHPNILHJ_00583 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
MHPNILHJ_00584 5.05e-258 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
MHPNILHJ_00585 4.21e-217 ykvZ - - K - - - Transcriptional regulator
MHPNILHJ_00586 1.54e-196 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
MHPNILHJ_00587 0.0 ptsG 2.7.1.199 - G ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MHPNILHJ_00588 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
MHPNILHJ_00589 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MHPNILHJ_00590 1.22e-48 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
MHPNILHJ_00591 2.29e-252 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
MHPNILHJ_00592 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
MHPNILHJ_00593 5.71e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
MHPNILHJ_00594 9.19e-65 - - - - - - - -
MHPNILHJ_00595 1.7e-167 ykwD - - J - - - protein with SCP PR1 domains
MHPNILHJ_00596 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
MHPNILHJ_00597 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MHPNILHJ_00598 5.43e-274 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MHPNILHJ_00599 2.22e-15 - - - - - - - -
MHPNILHJ_00600 1.3e-211 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
MHPNILHJ_00601 1.45e-107 ykyB - - S - - - YkyB-like protein
MHPNILHJ_00602 2e-302 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
MHPNILHJ_00603 3.48e-114 ykuD - - S - - - protein conserved in bacteria
MHPNILHJ_00604 7.29e-188 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
MHPNILHJ_00605 1.33e-175 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHPNILHJ_00607 1.74e-293 ykuI - - T - - - Diguanylate phosphodiesterase
MHPNILHJ_00608 2.11e-49 ykuJ - - S - - - protein conserved in bacteria
MHPNILHJ_00609 6.94e-117 ykuK - - S ko:K09776 - ko00000 Ribonuclease H-like
MHPNILHJ_00610 2.63e-36 ykzF - - S - - - Antirepressor AbbA
MHPNILHJ_00611 8.55e-99 ykuL - - S - - - CBS domain
MHPNILHJ_00612 1.08e-214 ccpC - - K - - - Transcriptional regulator
MHPNILHJ_00613 2.92e-113 ykuN - - C ko:K03839 - ko00000 Flavodoxin
MHPNILHJ_00614 1.07e-207 ykuO - - - - - - -
MHPNILHJ_00615 2.61e-95 fld - - C ko:K03839 - ko00000 Flavodoxin
MHPNILHJ_00616 4.79e-128 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MHPNILHJ_00617 8.58e-271 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MHPNILHJ_00618 1.25e-51 ykuS - - S - - - Belongs to the UPF0180 family
MHPNILHJ_00619 5.77e-177 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
MHPNILHJ_00621 1.9e-93 ykuV - - CO - - - thiol-disulfide
MHPNILHJ_00623 3.55e-125 rok - - K - - - Repressor of ComK
MHPNILHJ_00624 8.39e-201 yknT - - - ko:K06437 - ko00000 -
MHPNILHJ_00625 3.85e-130 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
MHPNILHJ_00626 1.45e-233 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MHPNILHJ_00627 7.3e-305 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
MHPNILHJ_00628 3.06e-111 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
MHPNILHJ_00629 1.19e-107 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
MHPNILHJ_00630 4.7e-43 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MHPNILHJ_00631 5.77e-134 yknW - - S - - - Yip1 domain
MHPNILHJ_00632 7e-224 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MHPNILHJ_00633 3.39e-157 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHPNILHJ_00634 4.52e-264 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
MHPNILHJ_00635 8.9e-168 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
MHPNILHJ_00636 8.8e-210 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
MHPNILHJ_00637 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
MHPNILHJ_00638 3.77e-138 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MHPNILHJ_00639 3.54e-48 ykoA - - - - - - -
MHPNILHJ_00640 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MHPNILHJ_00641 4.63e-200 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MHPNILHJ_00642 1.63e-300 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
MHPNILHJ_00643 7.7e-19 - - - S - - - Uncharacterized protein YkpC
MHPNILHJ_00644 6.17e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
MHPNILHJ_00645 7.46e-59 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
MHPNILHJ_00646 9.16e-301 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
MHPNILHJ_00647 3.99e-192 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
MHPNILHJ_00648 9.71e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
MHPNILHJ_00649 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MHPNILHJ_00650 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MHPNILHJ_00651 7.4e-41 ykzG - - S - - - Belongs to the UPF0356 family
MHPNILHJ_00652 3.14e-180 ykrA - - S - - - hydrolases of the HAD superfamily
MHPNILHJ_00653 1.49e-126 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MHPNILHJ_00654 4.93e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
MHPNILHJ_00655 9.3e-84 ykyA - - L - - - Putative cell-wall binding lipoprotein
MHPNILHJ_00656 1.04e-249 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MHPNILHJ_00657 5.84e-226 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MHPNILHJ_00658 6.09e-294 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MHPNILHJ_00659 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MHPNILHJ_00660 6.84e-60 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
MHPNILHJ_00661 3.33e-173 pdaA_2 3.5.1.104 - G ko:K01567,ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
MHPNILHJ_00662 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
MHPNILHJ_00663 5.44e-56 yktA - - S - - - Belongs to the UPF0223 family
MHPNILHJ_00664 3.32e-154 yktB - - S - - - Belongs to the UPF0637 family
MHPNILHJ_00665 7.89e-32 ykzI - - - - - - -
MHPNILHJ_00666 1.57e-193 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
MHPNILHJ_00667 1.08e-92 ykzC - - S - - - Acetyltransferase (GNAT) family
MHPNILHJ_00668 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
MHPNILHJ_00669 9.3e-32 ylaA - - - - - - -
MHPNILHJ_00671 1.62e-56 ylaE - - - - - - -
MHPNILHJ_00672 5.62e-33 - - - S - - - Family of unknown function (DUF5325)
MHPNILHJ_00673 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
MHPNILHJ_00674 1.41e-64 - - - S - - - YlaH-like protein
MHPNILHJ_00675 7.95e-45 ylaI - - S - - - protein conserved in bacteria
MHPNILHJ_00676 1.88e-129 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MHPNILHJ_00677 4.29e-310 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
MHPNILHJ_00678 7.69e-105 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MHPNILHJ_00679 1.94e-216 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
MHPNILHJ_00680 1.99e-58 ylaN - - S - - - Belongs to the UPF0358 family
MHPNILHJ_00681 3.73e-266 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
MHPNILHJ_00682 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MHPNILHJ_00683 3.88e-211 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
MHPNILHJ_00684 2.95e-209 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MHPNILHJ_00685 2.78e-251 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
MHPNILHJ_00686 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MHPNILHJ_00687 3.43e-141 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
MHPNILHJ_00688 3.53e-69 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
MHPNILHJ_00689 1.35e-207 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
MHPNILHJ_00690 8.01e-77 ylbA - - S - - - YugN-like family
MHPNILHJ_00691 1.31e-93 ylbB - - T - - - COG0517 FOG CBS domain
MHPNILHJ_00692 5.8e-248 ylbC - - S - - - protein with SCP PR1 domains
MHPNILHJ_00693 5.5e-83 ylbD - - S - - - Putative coat protein
MHPNILHJ_00694 1.73e-48 ylbE - - S - - - YlbE-like protein
MHPNILHJ_00695 3.73e-94 ylbF - - S - - - Belongs to the UPF0342 family
MHPNILHJ_00696 4.62e-56 ylbG - - S - - - UPF0298 protein
MHPNILHJ_00697 4.27e-126 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
MHPNILHJ_00698 2.38e-109 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MHPNILHJ_00699 8.16e-268 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
MHPNILHJ_00700 2.03e-177 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
MHPNILHJ_00701 7.74e-234 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
MHPNILHJ_00702 1.26e-281 ylbM - - S - - - Belongs to the UPF0348 family
MHPNILHJ_00703 4.69e-115 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
MHPNILHJ_00704 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
MHPNILHJ_00705 1.65e-106 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
MHPNILHJ_00706 2.68e-115 ylbP - - K - - - n-acetyltransferase
MHPNILHJ_00707 4.86e-194 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MHPNILHJ_00708 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
MHPNILHJ_00709 9.07e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
MHPNILHJ_00710 1.66e-218 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MHPNILHJ_00711 2.81e-67 ftsL - - D - - - Essential cell division protein
MHPNILHJ_00712 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
MHPNILHJ_00713 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
MHPNILHJ_00714 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MHPNILHJ_00715 2.36e-220 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MHPNILHJ_00716 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MHPNILHJ_00717 2.7e-236 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
MHPNILHJ_00718 9.42e-258 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MHPNILHJ_00719 3.07e-210 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
MHPNILHJ_00720 1.07e-169 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MHPNILHJ_00721 3.7e-297 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MHPNILHJ_00722 4.32e-259 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MHPNILHJ_00723 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
MHPNILHJ_00724 2.17e-213 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
MHPNILHJ_00725 3.64e-161 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHPNILHJ_00726 3.8e-178 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHPNILHJ_00727 2.58e-183 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
MHPNILHJ_00728 1.67e-308 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
MHPNILHJ_00729 7.13e-52 ylmC - - S - - - sporulation protein
MHPNILHJ_00730 3.85e-196 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
MHPNILHJ_00731 6.55e-155 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MHPNILHJ_00732 8.91e-83 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MHPNILHJ_00733 5.12e-56 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
MHPNILHJ_00734 3.8e-176 ylmH - - S - - - conserved protein, contains S4-like domain
MHPNILHJ_00735 1.85e-99 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
MHPNILHJ_00736 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MHPNILHJ_00737 4.22e-83 ylyA - - T - - - COG1734 DnaK suppressor protein
MHPNILHJ_00738 8.42e-102 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MHPNILHJ_00739 7.29e-214 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MHPNILHJ_00740 2.21e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MHPNILHJ_00741 8.98e-293 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
MHPNILHJ_00742 2.06e-204 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
MHPNILHJ_00743 1.67e-309 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MHPNILHJ_00744 4.71e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
MHPNILHJ_00745 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
MHPNILHJ_00746 2.68e-176 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
MHPNILHJ_00747 1.17e-218 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MHPNILHJ_00748 2.37e-159 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MHPNILHJ_00749 3.5e-146 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MHPNILHJ_00750 7.81e-178 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
MHPNILHJ_00751 5.26e-223 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
MHPNILHJ_00752 5.92e-282 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
MHPNILHJ_00753 1.31e-140 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
MHPNILHJ_00754 6.08e-178 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
MHPNILHJ_00755 1.13e-175 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
MHPNILHJ_00756 1.85e-98 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
MHPNILHJ_00757 0.0 - 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
MHPNILHJ_00758 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
MHPNILHJ_00759 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
MHPNILHJ_00760 3.26e-193 yloC - - S - - - stress-induced protein
MHPNILHJ_00761 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
MHPNILHJ_00762 1.16e-142 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
MHPNILHJ_00763 2.53e-38 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MHPNILHJ_00764 2.84e-283 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MHPNILHJ_00765 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MHPNILHJ_00766 1.61e-107 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MHPNILHJ_00767 6.66e-215 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MHPNILHJ_00768 6.91e-314 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MHPNILHJ_00769 3.58e-262 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MHPNILHJ_00770 2.84e-168 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
MHPNILHJ_00771 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
MHPNILHJ_00772 5.97e-209 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MHPNILHJ_00773 1.69e-148 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
MHPNILHJ_00774 5.45e-146 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
MHPNILHJ_00775 3.49e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
MHPNILHJ_00776 6.07e-77 yloU - - S - - - protein conserved in bacteria
MHPNILHJ_00777 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
MHPNILHJ_00778 1.69e-152 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
MHPNILHJ_00779 3.97e-200 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
MHPNILHJ_00780 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MHPNILHJ_00781 2.96e-119 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
MHPNILHJ_00782 2.58e-228 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MHPNILHJ_00783 2.08e-215 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
MHPNILHJ_00784 5.81e-166 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
MHPNILHJ_00785 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
MHPNILHJ_00786 2.48e-173 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MHPNILHJ_00787 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
MHPNILHJ_00788 2.09e-221 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MHPNILHJ_00789 1.97e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MHPNILHJ_00790 2e-301 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MHPNILHJ_00791 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
MHPNILHJ_00792 4.9e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
MHPNILHJ_00793 8.03e-79 ylqD - - S - - - YlqD protein
MHPNILHJ_00794 4.17e-119 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MHPNILHJ_00795 2.22e-173 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
MHPNILHJ_00796 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MHPNILHJ_00797 5.95e-202 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MHPNILHJ_00798 1.87e-171 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MHPNILHJ_00799 0.0 ylqG - - - - - - -
MHPNILHJ_00800 6.68e-57 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
MHPNILHJ_00801 1.66e-269 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MHPNILHJ_00802 7.59e-214 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MHPNILHJ_00803 6.19e-208 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
MHPNILHJ_00804 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MHPNILHJ_00805 1.05e-311 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MHPNILHJ_00806 1.42e-216 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
MHPNILHJ_00807 1.43e-118 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MHPNILHJ_00808 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MHPNILHJ_00809 7.94e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MHPNILHJ_00810 3.14e-81 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
MHPNILHJ_00811 1.46e-96 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
MHPNILHJ_00812 1.51e-50 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
MHPNILHJ_00813 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
MHPNILHJ_00814 3.52e-229 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MHPNILHJ_00815 2.13e-14 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
MHPNILHJ_00816 6.24e-102 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
MHPNILHJ_00817 2.02e-306 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
MHPNILHJ_00818 2.17e-92 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
MHPNILHJ_00819 3.78e-76 ylxF - - S - - - MgtE intracellular N domain
MHPNILHJ_00820 7.87e-242 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
MHPNILHJ_00821 2.43e-90 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
MHPNILHJ_00822 2.56e-175 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
MHPNILHJ_00823 3.66e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
MHPNILHJ_00824 1.28e-228 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MHPNILHJ_00825 9.42e-231 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MHPNILHJ_00826 2.12e-77 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
MHPNILHJ_00827 6.3e-142 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
MHPNILHJ_00828 1.21e-141 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
MHPNILHJ_00829 9.02e-51 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
MHPNILHJ_00830 4.51e-165 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
MHPNILHJ_00831 3.29e-238 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MHPNILHJ_00832 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MHPNILHJ_00833 4.59e-210 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
MHPNILHJ_00834 1.43e-196 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
MHPNILHJ_00835 2.95e-241 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
MHPNILHJ_00836 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
MHPNILHJ_00837 1.01e-104 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
MHPNILHJ_00838 1.39e-141 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
MHPNILHJ_00839 6.74e-112 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
MHPNILHJ_00840 3.96e-177 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHPNILHJ_00841 1.47e-83 ylxL - - - - - - -
MHPNILHJ_00842 1.74e-167 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
MHPNILHJ_00843 4.66e-200 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MHPNILHJ_00844 7.09e-164 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
MHPNILHJ_00845 1.59e-117 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MHPNILHJ_00846 2.49e-183 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MHPNILHJ_00847 1.48e-176 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
MHPNILHJ_00848 8.59e-271 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MHPNILHJ_00849 2.58e-293 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
MHPNILHJ_00850 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MHPNILHJ_00851 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MHPNILHJ_00852 9.4e-105 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
MHPNILHJ_00853 1.35e-262 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
MHPNILHJ_00854 6.76e-56 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
MHPNILHJ_00855 6.16e-63 ylxQ - - J - - - ribosomal protein
MHPNILHJ_00856 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MHPNILHJ_00857 1.11e-59 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
MHPNILHJ_00858 1.03e-73 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MHPNILHJ_00859 2.64e-214 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MHPNILHJ_00860 6.31e-224 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
MHPNILHJ_00861 4.12e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MHPNILHJ_00862 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MHPNILHJ_00863 2.3e-229 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
MHPNILHJ_00864 9.79e-298 mlpA - - S - - - Belongs to the peptidase M16 family
MHPNILHJ_00865 2.17e-56 ymxH - - S - - - YlmC YmxH family
MHPNILHJ_00866 4.32e-202 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
MHPNILHJ_00867 6.97e-131 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
MHPNILHJ_00868 5.33e-244 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MHPNILHJ_00869 1.83e-278 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
MHPNILHJ_00870 7.2e-202 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MHPNILHJ_00871 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MHPNILHJ_00872 5.34e-165 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
MHPNILHJ_00873 7.4e-41 - - - S - - - YlzJ-like protein
MHPNILHJ_00874 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
MHPNILHJ_00875 1.38e-166 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
MHPNILHJ_00876 2.76e-290 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
MHPNILHJ_00877 7.8e-97 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MHPNILHJ_00878 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
MHPNILHJ_00879 8.12e-300 albE - - S - - - Peptidase M16
MHPNILHJ_00880 2.09e-303 ymfH - - S - - - zinc protease
MHPNILHJ_00881 1.13e-161 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
MHPNILHJ_00882 6.23e-56 ymfJ - - S - - - Protein of unknown function (DUF3243)
MHPNILHJ_00883 3.66e-182 ymfK - - S - - - Protein of unknown function (DUF3388)
MHPNILHJ_00884 2.26e-166 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
MHPNILHJ_00885 2.75e-131 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MHPNILHJ_00886 2.57e-291 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
MHPNILHJ_00887 8.4e-237 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MHPNILHJ_00888 4.31e-260 pbpX - - V - - - Beta-lactamase
MHPNILHJ_00889 2.91e-308 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
MHPNILHJ_00890 3.06e-195 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
MHPNILHJ_00891 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
MHPNILHJ_00892 1.32e-247 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
MHPNILHJ_00893 7.6e-269 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MHPNILHJ_00894 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MHPNILHJ_00895 2.37e-85 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
MHPNILHJ_00896 3.93e-116 cotE - - S ko:K06328 - ko00000 Spore coat protein
MHPNILHJ_00897 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MHPNILHJ_00898 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MHPNILHJ_00899 3.58e-160 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
MHPNILHJ_00900 1.77e-202 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
MHPNILHJ_00901 9.59e-220 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
MHPNILHJ_00902 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
MHPNILHJ_00903 6.16e-48 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
MHPNILHJ_00904 9.98e-307 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
MHPNILHJ_00905 7.4e-179 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
MHPNILHJ_00906 6.35e-176 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
MHPNILHJ_00907 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
MHPNILHJ_00908 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
MHPNILHJ_00909 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
MHPNILHJ_00910 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
MHPNILHJ_00911 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
MHPNILHJ_00912 4.53e-283 cypA 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
MHPNILHJ_00913 3e-93 nucB - - M - - - Deoxyribonuclease NucA/NucB
MHPNILHJ_00914 3.52e-149 yoaK - - S - - - Membrane
MHPNILHJ_00915 9.32e-81 ymzB - - - - - - -
MHPNILHJ_00916 9.4e-317 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
MHPNILHJ_00917 2.64e-07 - - - - - - - -
MHPNILHJ_00918 3.08e-151 ymaC - - S - - - Replication protein
MHPNILHJ_00919 9.17e-100 ymaD - - O - - - redox protein, regulator of disulfide bond formation
MHPNILHJ_00920 1.76e-70 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
MHPNILHJ_00921 1.17e-62 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
MHPNILHJ_00923 9.08e-72 ymaF - - S - - - YmaF family
MHPNILHJ_00924 7.19e-210 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MHPNILHJ_00925 9e-46 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
MHPNILHJ_00926 1.87e-53 - - - - - - - -
MHPNILHJ_00927 2.31e-29 ymzA - - - - - - -
MHPNILHJ_00928 4.43e-77 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
MHPNILHJ_00929 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MHPNILHJ_00930 5.94e-237 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MHPNILHJ_00931 2.21e-132 ymaB - - S - - - MutT family
MHPNILHJ_00932 3.91e-05 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
MHPNILHJ_00933 2e-112 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
MHPNILHJ_00934 2.58e-225 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
MHPNILHJ_00935 9.64e-289 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MHPNILHJ_00936 5.35e-307 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
MHPNILHJ_00937 8.18e-86 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
MHPNILHJ_00938 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
MHPNILHJ_00941 6.66e-151 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
MHPNILHJ_00942 1.54e-271 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
MHPNILHJ_00943 8.41e-314 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
MHPNILHJ_00944 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
MHPNILHJ_00945 6.16e-263 xylR - - GK - - - ROK family
MHPNILHJ_00946 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
MHPNILHJ_00947 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
MHPNILHJ_00948 4.44e-150 - 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
MHPNILHJ_00949 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
MHPNILHJ_00950 7.81e-116 - - - K - - - Transcriptional regulator, TetR family
MHPNILHJ_00951 3.77e-225 bdhA 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
MHPNILHJ_00953 7.33e-250 - - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
MHPNILHJ_00954 0.000425 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
MHPNILHJ_00956 1.08e-86 dinB - - S - - - DinB family
MHPNILHJ_00957 3.67e-231 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
MHPNILHJ_00958 5.82e-16 - - - - - - - -
MHPNILHJ_00959 2.04e-10 - - - - - - - -
MHPNILHJ_00960 1.95e-39 - - - S - - - Protein of unknown function (DUF4025)
MHPNILHJ_00961 1.69e-13 ywlA - - S - - - Uncharacterised protein family (UPF0715)
MHPNILHJ_00962 1.52e-164 yoaP - - K - - - YoaP-like
MHPNILHJ_00963 1.09e-117 - - - J - - - Acetyltransferase (GNAT) domain
MHPNILHJ_00965 1.87e-53 - - - - - - - -
MHPNILHJ_00967 2.39e-130 - - - S - - - Domain of unknown function (DUF3885)
MHPNILHJ_00968 1.34e-238 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MHPNILHJ_00969 3.2e-150 - - AA10,CBM73 S ko:K03933 - ko00000 Pfam:Chitin_bind_3
MHPNILHJ_00970 9.32e-06 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
MHPNILHJ_00971 1.97e-119 yvgO - - - - - - -
MHPNILHJ_00973 0.0 yobO - - M - - - Pectate lyase superfamily protein
MHPNILHJ_00974 1.33e-43 - - - S - - - TM2 domain
MHPNILHJ_00975 9.69e-99 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
MHPNILHJ_00976 3.99e-33 - - - S - - - Domain of unknown function (DUF4177)
MHPNILHJ_00977 2.53e-162 yndL - - S - - - Replication protein
MHPNILHJ_00978 4.12e-10 - - - - - - - -
MHPNILHJ_00979 4.95e-182 - - - O - - - COG0330 Membrane protease subunits, stomatin prohibitin homologs
MHPNILHJ_00980 2.23e-86 yndM - - S - - - Protein of unknown function (DUF2512)
MHPNILHJ_00982 7.8e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MHPNILHJ_00983 4.8e-66 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
MHPNILHJ_00984 4.8e-141 yneB - - L - - - resolvase
MHPNILHJ_00985 2.33e-43 ynzC - - S - - - UPF0291 protein
MHPNILHJ_00986 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MHPNILHJ_00987 3.48e-103 yneE - - S - - - Sporulation inhibitor of replication protein sirA
MHPNILHJ_00988 6.2e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
MHPNILHJ_00989 8.06e-33 ynzD - - S - - - Spo0E like sporulation regulatory protein
MHPNILHJ_00990 1.38e-158 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
MHPNILHJ_00991 4.11e-75 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
MHPNILHJ_00992 7.59e-97 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
MHPNILHJ_00993 4.28e-92 yneK - - S - - - Protein of unknown function (DUF2621)
MHPNILHJ_00994 2.64e-77 cotM - - O ko:K06335 - ko00000 Spore coat protein
MHPNILHJ_00995 1.97e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
MHPNILHJ_00996 6.2e-22 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
MHPNILHJ_00997 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MHPNILHJ_00998 4.36e-114 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MHPNILHJ_01000 4.08e-43 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
MHPNILHJ_01001 8.11e-95 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
MHPNILHJ_01002 5.95e-65 yneQ - - - - - - -
MHPNILHJ_01003 9.38e-58 yneR - - S - - - Belongs to the HesB IscA family
MHPNILHJ_01004 1.51e-119 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MHPNILHJ_01005 1.41e-89 yneT - - S ko:K06929 - ko00000 CoA-binding protein
MHPNILHJ_01006 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MHPNILHJ_01007 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MHPNILHJ_01008 2.21e-19 - - - - - - - -
MHPNILHJ_01009 2.04e-60 ynfC - - - - - - -
MHPNILHJ_01010 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
MHPNILHJ_01011 1.56e-28 yndG - - S - - - DoxX-like family
MHPNILHJ_01012 2.24e-99 - - - S - - - Domain of unknown function (DUF4166)
MHPNILHJ_01013 0.0 yndJ - - S - - - YndJ-like protein
MHPNILHJ_01014 2.03e-67 yvlA - - S - - - Domain of unknown function (DUF4870)
MHPNILHJ_01015 3.49e-282 - - - T - - - Histidine kinase
MHPNILHJ_01016 1.84e-155 - - - T - - - Transcriptional regulatory protein, C terminal
MHPNILHJ_01017 2.01e-303 - 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
MHPNILHJ_01018 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
MHPNILHJ_01019 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHPNILHJ_01020 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHPNILHJ_01021 0.0 nrsA - - Q ko:K15661 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHPNILHJ_01022 3.84e-262 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
MHPNILHJ_01023 1.26e-156 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
MHPNILHJ_01024 6.43e-136 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MHPNILHJ_01025 2.32e-145 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MHPNILHJ_01026 6.2e-207 bioI 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
MHPNILHJ_01027 5.98e-242 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MHPNILHJ_01028 7.37e-158 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MHPNILHJ_01029 3.12e-254 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MHPNILHJ_01030 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
MHPNILHJ_01031 8.22e-171 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
MHPNILHJ_01032 1.02e-88 yngA - - S - - - membrane
MHPNILHJ_01033 1.01e-196 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
MHPNILHJ_01034 6.22e-134 yngC - - S - - - SNARE associated Golgi protein
MHPNILHJ_01035 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MHPNILHJ_01036 2.54e-171 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
MHPNILHJ_01037 2.16e-208 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
MHPNILHJ_01038 2.28e-40 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
MHPNILHJ_01039 1.6e-304 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
MHPNILHJ_01040 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MHPNILHJ_01041 6.97e-264 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
MHPNILHJ_01042 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
MHPNILHJ_01043 9.31e-83 yngL - - S - - - Protein of unknown function (DUF1360)
MHPNILHJ_01044 0.0 - - - Q ko:K15656,ko:K15668 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 D-alanine [D-alanyl carrier protein] ligase activity
MHPNILHJ_01045 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHPNILHJ_01046 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
MHPNILHJ_01047 3.16e-229 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
MHPNILHJ_01048 9.25e-306 yoeA - - V - - - MATE efflux family protein
MHPNILHJ_01049 2.04e-122 yoeB - - S - - - IseA DL-endopeptidase inhibitor
MHPNILHJ_01051 7.69e-123 - - - L - - - Integrase
MHPNILHJ_01052 7.83e-46 yoeD - - G - - - Helix-turn-helix domain
MHPNILHJ_01053 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
MHPNILHJ_01054 2.7e-246 - - - EGP ko:K08164 - ko00000,ko02000 -transporter
MHPNILHJ_01055 1.91e-66 - - - K - - - Helix-turn-helix domain
MHPNILHJ_01056 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MHPNILHJ_01057 8.19e-187 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
MHPNILHJ_01058 1.88e-225 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
MHPNILHJ_01059 5.73e-60 - - - S - - - Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
MHPNILHJ_01060 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
MHPNILHJ_01061 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
MHPNILHJ_01062 7.74e-201 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
MHPNILHJ_01063 3.37e-251 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MHPNILHJ_01064 5.78e-173 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MHPNILHJ_01065 6.69e-81 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
MHPNILHJ_01066 4.03e-156 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
MHPNILHJ_01067 1.23e-49 - - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MHPNILHJ_01068 1.2e-147 yoxB - - - - - - -
MHPNILHJ_01069 1.18e-261 yoaB - - EGP - - - the major facilitator superfamily
MHPNILHJ_01070 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
MHPNILHJ_01071 8.38e-238 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MHPNILHJ_01072 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MHPNILHJ_01073 7.68e-37 yoaF - - - - - - -
MHPNILHJ_01075 1.5e-124 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MHPNILHJ_01076 2.96e-49 - - - - - - - -
MHPNILHJ_01080 2.04e-68 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
MHPNILHJ_01081 6.26e-156 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
MHPNILHJ_01082 1.44e-110 yobS - - K - - - Transcriptional regulator
MHPNILHJ_01083 1.22e-159 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
MHPNILHJ_01084 1.51e-116 yobW - - - - - - -
MHPNILHJ_01085 3.14e-72 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
MHPNILHJ_01086 5.45e-154 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MHPNILHJ_01087 5.42e-117 yozB - - S ko:K08976 - ko00000 membrane
MHPNILHJ_01088 2.97e-173 - - - J - - - Protein required for attachment to host cells
MHPNILHJ_01089 2.99e-119 yocC - - - - - - -
MHPNILHJ_01090 8.07e-233 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
MHPNILHJ_01092 6.61e-157 yocH - - M - - - COG1388 FOG LysM repeat
MHPNILHJ_01093 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
MHPNILHJ_01095 2.71e-143 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MHPNILHJ_01096 7.44e-78 yocK - - T - - - general stress protein
MHPNILHJ_01098 1.16e-11 yocN - - - - - - -
MHPNILHJ_01099 2.21e-114 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
MHPNILHJ_01100 1.13e-58 yozN - - - - - - -
MHPNILHJ_01101 1.83e-49 yocN - - - - - - -
MHPNILHJ_01102 5.32e-75 yozO - - S - - - Bacterial PH domain
MHPNILHJ_01103 4.69e-43 yozC - - - - - - -
MHPNILHJ_01104 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
MHPNILHJ_01105 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
MHPNILHJ_01106 5.12e-207 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
MHPNILHJ_01107 3.13e-293 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MHPNILHJ_01108 3.93e-208 yocS - - S ko:K03453 - ko00000 -transporter
MHPNILHJ_01109 3.22e-164 - - - S - - - Metallo-beta-lactamase superfamily
MHPNILHJ_01110 1.12e-257 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
MHPNILHJ_01111 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
MHPNILHJ_01112 0.0 yojO - - P - - - Von Willebrand factor
MHPNILHJ_01113 2e-207 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
MHPNILHJ_01114 2.75e-137 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MHPNILHJ_01115 1.68e-276 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
MHPNILHJ_01116 1.97e-277 - - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
MHPNILHJ_01117 3.97e-136 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MHPNILHJ_01119 1.51e-297 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
MHPNILHJ_01120 6.24e-187 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MHPNILHJ_01121 2.61e-161 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
MHPNILHJ_01122 4.69e-79 yojF - - S - - - Protein of unknown function (DUF1806)
MHPNILHJ_01123 3.66e-31 - - - - - - - -
MHPNILHJ_01124 3.04e-203 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
MHPNILHJ_01125 1.83e-101 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
MHPNILHJ_01127 9.37e-83 iolK - - S - - - tautomerase
MHPNILHJ_01128 1.93e-69 yodB - - K - - - transcriptional
MHPNILHJ_01129 5.26e-136 yodC - - C - - - nitroreductase
MHPNILHJ_01130 1.35e-137 yahD - - S ko:K06999 - ko00000 Carboxylesterase
MHPNILHJ_01131 5.32e-213 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
MHPNILHJ_01132 1.14e-27 - - - S - - - Protein of unknown function (DUF3311)
MHPNILHJ_01133 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MHPNILHJ_01134 0.0 - 3.2.1.45 GH30 M ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 ko00000,ko00001,ko01000 Glycosyl hydrolase family 30 beta sandwich domain
MHPNILHJ_01135 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MHPNILHJ_01136 3.79e-164 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
MHPNILHJ_01137 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
MHPNILHJ_01138 4.97e-156 yodH - - Q - - - Methyltransferase
MHPNILHJ_01139 2.3e-30 yodI - - - - - - -
MHPNILHJ_01140 8.69e-190 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
MHPNILHJ_01141 4.29e-161 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
MHPNILHJ_01143 1.16e-72 yodL - - S - - - YodL-like
MHPNILHJ_01144 8.36e-131 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
MHPNILHJ_01145 1.97e-33 yozD - - S - - - YozD-like protein
MHPNILHJ_01147 1.18e-155 yodN - - - - - - -
MHPNILHJ_01148 1.39e-66 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MHPNILHJ_01149 2.87e-47 yozE - - S - - - Belongs to the UPF0346 family
MHPNILHJ_01150 6.45e-59 yokU - - S - - - YokU-like protein, putative antitoxin
MHPNILHJ_01151 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
MHPNILHJ_01152 4.82e-180 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
MHPNILHJ_01153 6.72e-316 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
MHPNILHJ_01154 8.26e-154 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MHPNILHJ_01155 1.05e-155 atoD 2.8.3.8, 2.8.3.9 - I ko:K01034 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MHPNILHJ_01156 7.19e-298 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MHPNILHJ_01158 8.69e-84 - - - L - - - Bacterial transcription activator, effector binding domain
MHPNILHJ_01160 7.99e-176 yiiD - - K ko:K06323 - ko00000 acetyltransferase
MHPNILHJ_01161 7.04e-288 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
MHPNILHJ_01162 4.04e-54 cgeC - - - ko:K06321 - ko00000 -
MHPNILHJ_01163 9.24e-83 cgeA - - - ko:K06319 - ko00000 -
MHPNILHJ_01164 3.73e-214 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
MHPNILHJ_01165 5.79e-269 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
MHPNILHJ_01166 5.78e-91 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
MHPNILHJ_01168 5.97e-151 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 FMN-dependent dehydrogenase
MHPNILHJ_01170 6.05e-22 - - - S - - - Regulatory protein YrvL
MHPNILHJ_01171 6.94e-262 yokA - - L - - - Recombinase
MHPNILHJ_01172 1.29e-129 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
MHPNILHJ_01173 2.47e-101 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
MHPNILHJ_01174 1.34e-130 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MHPNILHJ_01175 1.42e-88 ypoP - - K - - - transcriptional
MHPNILHJ_01176 2.45e-122 ypmS - - S - - - protein conserved in bacteria
MHPNILHJ_01177 3.62e-167 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
MHPNILHJ_01178 2.24e-131 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
MHPNILHJ_01179 3.66e-54 ypmP - - S - - - Protein of unknown function (DUF2535)
MHPNILHJ_01180 7.88e-305 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MHPNILHJ_01181 1.54e-207 yplP - - K - - - Transcriptional regulator
MHPNILHJ_01182 7.14e-141 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
MHPNILHJ_01183 9.83e-141 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MHPNILHJ_01184 6.3e-110 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MHPNILHJ_01185 2.08e-202 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MHPNILHJ_01186 1.41e-142 ypjP - - S - - - YpjP-like protein
MHPNILHJ_01187 2.63e-167 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
MHPNILHJ_01188 1.38e-98 yphP - - S - - - Belongs to the UPF0403 family
MHPNILHJ_01189 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
MHPNILHJ_01190 8.12e-197 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
MHPNILHJ_01191 1.69e-116 yagB - - S ko:K06950 - ko00000 phosphohydrolase
MHPNILHJ_01192 4.95e-107 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
MHPNILHJ_01194 1.56e-225 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MHPNILHJ_01195 1.01e-272 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
MHPNILHJ_01196 5.12e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
MHPNILHJ_01197 4.27e-16 degR - - - - - - -
MHPNILHJ_01198 5.37e-48 - - - S - - - Protein of unknown function (DUF2564)
MHPNILHJ_01199 6.37e-38 ypeQ - - S - - - Zinc-finger
MHPNILHJ_01200 4.29e-152 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
MHPNILHJ_01201 3.96e-154 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MHPNILHJ_01202 3.51e-88 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
MHPNILHJ_01204 2.07e-204 ypcP - - L - - - 5'3' exonuclease
MHPNILHJ_01205 5.97e-11 - - - - - - - -
MHPNILHJ_01206 3e-45 ypbS - - S - - - Protein of unknown function (DUF2533)
MHPNILHJ_01207 0.0 ypbR - - S - - - Dynamin family
MHPNILHJ_01208 2.25e-111 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
MHPNILHJ_01209 3.81e-254 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
MHPNILHJ_01210 2.22e-130 - - - J - - - Acetyltransferase (GNAT) domain
MHPNILHJ_01211 8.02e-60 MGMT - - L ko:K07443 - ko00000 6-O-methylguanine DNA methyltransferase, DNA binding domain
MHPNILHJ_01212 2.2e-09 - - - S - - - Bacillus cereus group antimicrobial protein
MHPNILHJ_01213 4.84e-200 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine
MHPNILHJ_01215 1.53e-117 - - - L - - - Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MHPNILHJ_01221 2.2e-33 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MHPNILHJ_01222 1.33e-192 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MHPNILHJ_01226 3.14e-94 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
MHPNILHJ_01227 2.59e-68 - - - S - - - Peptidyl-tRNA hydrolase PTH2
MHPNILHJ_01228 6.38e-16 - - - O - - - Glutaredoxin
MHPNILHJ_01230 3.47e-55 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MHPNILHJ_01231 2.83e-121 - - - L - - - HNH endonuclease
MHPNILHJ_01232 2.37e-134 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MHPNILHJ_01234 3.71e-207 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MHPNILHJ_01235 8.27e-48 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MHPNILHJ_01236 7.02e-156 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MHPNILHJ_01237 1.54e-82 - - - S - - - NrdI Flavodoxin like
MHPNILHJ_01255 6.57e-202 ddeI 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 DNA (cytosine-5-)-methyltransferase activity
MHPNILHJ_01256 1.29e-112 yorS - - S - - - 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
MHPNILHJ_01257 2.04e-92 tmk 2.1.1.45, 2.7.4.9 - F ko:K00560,ko:K00943 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 dTDP biosynthetic process
MHPNILHJ_01261 4.35e-65 - - - S - - - protein conserved in bacteria
MHPNILHJ_01263 3.93e-144 - - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
MHPNILHJ_01264 3.09e-64 - - - S - - - DNA primase activity
MHPNILHJ_01265 1.94e-179 - - - L - - - Participates in initiation and elongation during chromosome replication
MHPNILHJ_01271 1.71e-69 pphA 3.1.3.16 - T ko:K07313 - ko00000,ko01000 Calcineurin-like phosphoesterase
MHPNILHJ_01272 9.82e-276 - - - M - - - Parallel beta-helix repeats
MHPNILHJ_01273 1.27e-106 - - - S - - - Pfam:DUF867
MHPNILHJ_01276 3.57e-205 - - - - - - - -
MHPNILHJ_01277 2.54e-10 - - - S - - - YopX protein
MHPNILHJ_01280 4e-162 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
MHPNILHJ_01281 1.42e-178 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 - L ko:K01971,ko:K10747 ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450 ko00000,ko00001,ko01000,ko03032,ko03400 ATP-dependent DNA ligase
MHPNILHJ_01287 2.26e-22 - - - - - - - -
MHPNILHJ_01291 1.93e-87 - 2.1.1.113 - L ko:K00590 - ko00000,ko01000,ko02048 Belongs to the N(4) N(6)-methyltransferase family
MHPNILHJ_01292 5.48e-32 - - - - - - - -
MHPNILHJ_01296 8.45e-82 - - - N - - - bacterial-type flagellum assembly
MHPNILHJ_01300 1.85e-54 - - - - - - - -
MHPNILHJ_01303 1.45e-30 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
MHPNILHJ_01304 4.49e-198 - - - - - - - -
MHPNILHJ_01305 2.71e-287 - - - S - - - DNA-sulfur modification-associated
MHPNILHJ_01306 5.81e-188 - - - L - - - Belongs to the 'phage' integrase family
MHPNILHJ_01311 2.07e-182 - - - - - - - -
MHPNILHJ_01315 6.34e-98 - - - - - - - -
MHPNILHJ_01329 4.89e-33 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
MHPNILHJ_01330 6.01e-89 yoaW - - - - - - -
MHPNILHJ_01331 1.15e-12 - - - I - - - Acyltransferase family
MHPNILHJ_01332 5.9e-11 ywlA - - S - - - Uncharacterised protein family (UPF0715)
MHPNILHJ_01333 1.93e-112 - - - - - - - -
MHPNILHJ_01335 3.25e-68 - - - - - - - -
MHPNILHJ_01336 5.83e-65 - - - S ko:K07741 - ko00000 Phage regulatory protein Rha (Phage_pRha)
MHPNILHJ_01337 0.0 - - - S - - - ATP-dependent DNA helicase activity
MHPNILHJ_01339 2.49e-176 - - - S - - - N-methyltransferase activity
MHPNILHJ_01340 4.06e-185 - - - S - - - DNA binding
MHPNILHJ_01341 4.26e-260 - - - - - - - -
MHPNILHJ_01343 1.54e-72 - - - D - - - Tubulin/FtsZ family, GTPase domain
MHPNILHJ_01347 0.0 - - - - - - - -
MHPNILHJ_01348 4.77e-47 - - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MHPNILHJ_01351 8.2e-287 - - - - - - - -
MHPNILHJ_01356 3.95e-107 - - - - - - - -
MHPNILHJ_01360 4.83e-84 - - - - - - - -
MHPNILHJ_01363 8.93e-72 - - - - - - - -
MHPNILHJ_01364 1.42e-109 - - - - - - - -
MHPNILHJ_01365 2.21e-147 - - - - - - - -
MHPNILHJ_01366 7.02e-72 - - - - - - - -
MHPNILHJ_01368 3.53e-64 - - - - - - - -
MHPNILHJ_01369 2.74e-44 - - - - - - - -
MHPNILHJ_01371 2.02e-106 - 3.1.4.46, 5.4.2.11 - C ko:K01126,ko:K01834 ko00010,ko00260,ko00564,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00564,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 glycerophosphoryl diester phosphodiesterase
MHPNILHJ_01372 1.26e-76 - - - - - - - -
MHPNILHJ_01373 3.68e-64 - - - - - - - -
MHPNILHJ_01374 2.1e-223 - - - A - - - Belongs to the 'phage' integrase family
MHPNILHJ_01376 3.21e-22 - - - - - - - -
MHPNILHJ_01377 1.13e-102 - - - KLT - - - Protein tyrosine kinase
MHPNILHJ_01380 1.93e-74 - - - - - - - -
MHPNILHJ_01381 9.94e-276 - - - S - - - peptidoglycan catabolic process
MHPNILHJ_01382 0.0 - - - S - - - peptidoglycan catabolic process
MHPNILHJ_01383 8.77e-109 - - - S - - - Phage tail protein
MHPNILHJ_01384 0.0 - - - S - - - Pfam Transposase IS66
MHPNILHJ_01386 2e-136 - - - - - - - -
MHPNILHJ_01387 0.0 - - - M - - - Pectate lyase superfamily protein
MHPNILHJ_01388 3.33e-97 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
MHPNILHJ_01390 2.14e-44 - - - S - - - Bacteriophage holin
MHPNILHJ_01392 1.05e-06 - - - - - - - -
MHPNILHJ_01393 3.53e-85 - - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
MHPNILHJ_01394 2.31e-23 - - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
MHPNILHJ_01396 6.19e-283 dinB2 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MHPNILHJ_01397 2.56e-53 - - - S - - - YolD-like protein
MHPNILHJ_01398 1.97e-26 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
MHPNILHJ_01399 5.79e-117 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
MHPNILHJ_01401 3.72e-100 - - - S - - - SMI1-KNR4 cell-wall
MHPNILHJ_01402 4.74e-227 - - - S - - - Bacterial EndoU nuclease
MHPNILHJ_01403 6.07e-172 - - - V - - - HNH endonuclease
MHPNILHJ_01404 7.74e-121 - - - G - - - SMI1-KNR4 cell-wall
MHPNILHJ_01405 5.36e-110 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
MHPNILHJ_01406 1.89e-47 - - - L - - - Recombinase
MHPNILHJ_01407 2.07e-76 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine
MHPNILHJ_01408 8.76e-124 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MHPNILHJ_01409 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MHPNILHJ_01410 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
MHPNILHJ_01412 6.91e-31 - - - S - - - YpzG-like protein
MHPNILHJ_01413 2.19e-96 yqgA - - - - - - -
MHPNILHJ_01414 3.07e-276 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
MHPNILHJ_01415 5.52e-61 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MHPNILHJ_01416 3.67e-126 ypsA - - S - - - Belongs to the UPF0398 family
MHPNILHJ_01417 8.12e-36 cotD - - S ko:K06327 - ko00000 Inner spore coat protein D
MHPNILHJ_01419 3.33e-285 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
MHPNILHJ_01420 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
MHPNILHJ_01421 6.99e-115 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
MHPNILHJ_01422 6.64e-80 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
MHPNILHJ_01423 2.64e-59 yppG - - S - - - YppG-like protein
MHPNILHJ_01428 1.05e-225 yppC - - S - - - Protein of unknown function (DUF2515)
MHPNILHJ_01429 8.49e-144 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MHPNILHJ_01430 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
MHPNILHJ_01431 4.6e-113 ypoC - - - - - - -
MHPNILHJ_01432 1.63e-154 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MHPNILHJ_01433 8.05e-166 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
MHPNILHJ_01434 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
MHPNILHJ_01435 1.1e-278 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
MHPNILHJ_01436 2.74e-95 ypmB - - S - - - protein conserved in bacteria
MHPNILHJ_01437 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
MHPNILHJ_01438 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
MHPNILHJ_01439 1.98e-83 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MHPNILHJ_01440 4.82e-194 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MHPNILHJ_01441 1.89e-191 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
MHPNILHJ_01442 2.04e-226 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MHPNILHJ_01443 1.53e-266 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MHPNILHJ_01444 2.45e-267 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
MHPNILHJ_01445 3.8e-162 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
MHPNILHJ_01446 3.58e-93 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
MHPNILHJ_01447 9.38e-187 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MHPNILHJ_01448 2.47e-74 ypjD - - S - - - Nucleotide pyrophosphohydrolase
MHPNILHJ_01449 6.13e-199 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
MHPNILHJ_01450 5.93e-282 - 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
MHPNILHJ_01451 1.09e-177 ypjB - - S - - - sporulation protein
MHPNILHJ_01452 6.12e-126 ypjA - - S - - - membrane
MHPNILHJ_01453 9.48e-190 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
MHPNILHJ_01454 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
MHPNILHJ_01455 2.27e-124 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
MHPNILHJ_01456 1.21e-94 ypiF - - S - - - Protein of unknown function (DUF2487)
MHPNILHJ_01457 2.14e-128 ypiB - - S - - - Belongs to the UPF0302 family
MHPNILHJ_01458 7.68e-292 ypiA - - S - - - COG0457 FOG TPR repeat
MHPNILHJ_01459 3.79e-290 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MHPNILHJ_01460 9.38e-256 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
MHPNILHJ_01461 2.67e-251 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MHPNILHJ_01462 1.08e-175 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MHPNILHJ_01463 9.2e-286 trpB 4.2.1.20 - E ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MHPNILHJ_01464 2.57e-141 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
MHPNILHJ_01465 5.7e-159 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
MHPNILHJ_01466 3.8e-201 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MHPNILHJ_01467 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MHPNILHJ_01468 8.09e-77 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
MHPNILHJ_01469 1.14e-253 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MHPNILHJ_01470 3.26e-274 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MHPNILHJ_01471 8e-178 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
MHPNILHJ_01472 2.01e-102 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
MHPNILHJ_01473 1.88e-250 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MHPNILHJ_01474 2.6e-167 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MHPNILHJ_01475 2.68e-175 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
MHPNILHJ_01476 6.23e-47 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
MHPNILHJ_01477 6.27e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
MHPNILHJ_01478 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MHPNILHJ_01479 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MHPNILHJ_01481 2.47e-166 yphF - - - - - - -
MHPNILHJ_01482 1.13e-23 yphE - - S - - - Protein of unknown function (DUF2768)
MHPNILHJ_01483 9.14e-240 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
MHPNILHJ_01484 2.86e-316 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
MHPNILHJ_01485 6.38e-129 yphA - - - - - - -
MHPNILHJ_01486 1.32e-12 - - - S - - - YpzI-like protein
MHPNILHJ_01487 4.76e-228 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MHPNILHJ_01488 3.17e-261 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
MHPNILHJ_01489 3.75e-142 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
MHPNILHJ_01490 1.12e-17 - - - S - - - Family of unknown function (DUF5359)
MHPNILHJ_01491 6.58e-72 ypfA - - M - - - Flagellar protein YcgR
MHPNILHJ_01492 1.1e-311 ypeB - - H ko:K06313 - ko00000 sporulation protein
MHPNILHJ_01493 2.15e-203 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
MHPNILHJ_01494 2.61e-155 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
MHPNILHJ_01495 5.93e-236 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
MHPNILHJ_01496 8.6e-310 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
MHPNILHJ_01497 1.59e-135 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MHPNILHJ_01498 5.62e-181 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
MHPNILHJ_01499 3.73e-109 ypbF - - S - - - Protein of unknown function (DUF2663)
MHPNILHJ_01500 8.85e-110 ypbE - - M - - - Lysin motif
MHPNILHJ_01501 2.24e-124 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
MHPNILHJ_01502 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
MHPNILHJ_01503 2.97e-244 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
MHPNILHJ_01504 5.88e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
MHPNILHJ_01505 3.59e-121 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MHPNILHJ_01506 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MHPNILHJ_01507 4.67e-216 rsiX - - - - - - -
MHPNILHJ_01508 3.09e-133 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MHPNILHJ_01509 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MHPNILHJ_01510 9.77e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHPNILHJ_01511 3.09e-252 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
MHPNILHJ_01512 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
MHPNILHJ_01513 2.05e-126 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
MHPNILHJ_01514 1.74e-166 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MHPNILHJ_01515 7.39e-115 spmB - - S ko:K06374 - ko00000 Spore maturation protein
MHPNILHJ_01516 6.22e-134 spmA - - S ko:K06373 - ko00000 Spore maturation protein
MHPNILHJ_01517 2.36e-268 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MHPNILHJ_01518 5.9e-107 ypuI - - S - - - Protein of unknown function (DUF3907)
MHPNILHJ_01519 1.3e-131 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MHPNILHJ_01520 4.93e-165 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MHPNILHJ_01522 2.41e-113 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
MHPNILHJ_01523 1.12e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MHPNILHJ_01524 1.4e-105 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MHPNILHJ_01525 8.2e-288 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MHPNILHJ_01526 1.09e-141 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
MHPNILHJ_01527 1.24e-257 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MHPNILHJ_01528 7.86e-68 ypuD - - - - - - -
MHPNILHJ_01529 2.37e-124 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MHPNILHJ_01530 6.23e-102 ccdC1 - - O - - - Protein of unknown function (DUF1453)
MHPNILHJ_01531 1.18e-103 ppiB 5.2.1.8 - O ko:K01802,ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MHPNILHJ_01532 1.17e-194 ypuA - - S - - - Secreted protein
MHPNILHJ_01533 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MHPNILHJ_01534 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
MHPNILHJ_01535 1.2e-138 - - - S ko:K06407 - ko00000 stage V sporulation protein
MHPNILHJ_01536 3.57e-74 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
MHPNILHJ_01537 9.17e-241 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
MHPNILHJ_01538 2.85e-103 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
MHPNILHJ_01539 7.71e-90 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
MHPNILHJ_01540 9.1e-141 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
MHPNILHJ_01541 6.81e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHPNILHJ_01542 4.77e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
MHPNILHJ_01543 1.98e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
MHPNILHJ_01544 5.58e-270 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MHPNILHJ_01545 8.69e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MHPNILHJ_01546 1.31e-289 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
MHPNILHJ_01547 1.78e-210 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
MHPNILHJ_01548 2.73e-50 - - - S - - - Protein of unknown function (DUF4227)
MHPNILHJ_01549 3.08e-102 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
MHPNILHJ_01550 4.12e-141 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
MHPNILHJ_01551 2.87e-43 yqkK - - - - - - -
MHPNILHJ_01552 5.05e-33 - - - - - - - -
MHPNILHJ_01553 9.28e-307 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
MHPNILHJ_01554 3.56e-313 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
MHPNILHJ_01555 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
MHPNILHJ_01556 4.88e-236 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
MHPNILHJ_01557 2.32e-75 ansR - - K - - - Transcriptional regulator
MHPNILHJ_01558 1.43e-271 yqxK - - L - - - DNA helicase
MHPNILHJ_01559 1.42e-120 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
MHPNILHJ_01560 5.78e-10 - - - S - - - Protein of unknown function (DUF3936)
MHPNILHJ_01561 2.34e-211 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
MHPNILHJ_01562 3.06e-15 yqkE - - S - - - Protein of unknown function (DUF3886)
MHPNILHJ_01563 2.61e-213 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
MHPNILHJ_01564 7.88e-54 yqkC - - S - - - Protein of unknown function (DUF2552)
MHPNILHJ_01565 1.22e-76 yqkB - - S - - - Belongs to the HesB IscA family
MHPNILHJ_01566 1.16e-213 yqkA - - K - - - GrpB protein
MHPNILHJ_01567 1.92e-08 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
MHPNILHJ_01568 2.7e-113 yqjY - - K ko:K06977 - ko00000 acetyltransferase
MHPNILHJ_01569 6.1e-295 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MHPNILHJ_01570 7.27e-73 - - - S - - - YolD-like protein
MHPNILHJ_01572 5.73e-206 yueF - - S - - - transporter activity
MHPNILHJ_01574 3.01e-225 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
MHPNILHJ_01575 4.1e-307 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
MHPNILHJ_01576 2.99e-174 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
MHPNILHJ_01577 1.11e-213 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
MHPNILHJ_01578 7.56e-181 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MHPNILHJ_01579 6.67e-204 - - - K - - - LysR substrate binding domain
MHPNILHJ_01580 2.42e-61 - - - S - - - GlpM protein
MHPNILHJ_01581 7.32e-247 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
MHPNILHJ_01582 2.4e-184 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MHPNILHJ_01583 4.44e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
MHPNILHJ_01584 2.97e-215 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MHPNILHJ_01585 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MHPNILHJ_01586 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MHPNILHJ_01587 7.78e-294 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MHPNILHJ_01588 2.26e-35 yqzJ - - - - - - -
MHPNILHJ_01589 6.56e-188 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MHPNILHJ_01590 5.04e-257 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
MHPNILHJ_01591 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MHPNILHJ_01592 6.09e-92 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
MHPNILHJ_01594 3.99e-118 yqjB - - S - - - protein conserved in bacteria
MHPNILHJ_01595 1.79e-216 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
MHPNILHJ_01596 2.77e-161 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
MHPNILHJ_01597 6.03e-141 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
MHPNILHJ_01598 2.18e-170 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
MHPNILHJ_01599 1.68e-99 yqiW - - S - - - Belongs to the UPF0403 family
MHPNILHJ_01600 3.22e-214 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MHPNILHJ_01601 2.69e-265 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MHPNILHJ_01602 4e-234 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MHPNILHJ_01603 4.18e-217 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MHPNILHJ_01604 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MHPNILHJ_01605 7.78e-260 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
MHPNILHJ_01606 5.27e-260 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
MHPNILHJ_01607 1.53e-191 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
MHPNILHJ_01608 0.0 bkdR - - KT - - - Transcriptional regulator
MHPNILHJ_01609 7.32e-46 yqzF - - S - - - Protein of unknown function (DUF2627)
MHPNILHJ_01610 7.1e-199 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MHPNILHJ_01611 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
MHPNILHJ_01612 9.85e-261 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
MHPNILHJ_01613 7.69e-255 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
MHPNILHJ_01614 1.86e-185 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
MHPNILHJ_01615 1.21e-266 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
MHPNILHJ_01616 1.04e-163 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
MHPNILHJ_01617 1.94e-127 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
MHPNILHJ_01619 2.52e-119 - - - P - - - Probably functions as a manganese efflux pump
MHPNILHJ_01620 3.85e-144 - - - K - - - Protein of unknown function (DUF1232)
MHPNILHJ_01622 2.85e-266 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
MHPNILHJ_01625 4.31e-260 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MHPNILHJ_01627 4.13e-185 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
MHPNILHJ_01628 5.48e-298 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
MHPNILHJ_01629 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
MHPNILHJ_01630 1.03e-100 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
MHPNILHJ_01631 2.69e-193 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
MHPNILHJ_01632 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MHPNILHJ_01633 7.16e-201 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MHPNILHJ_01634 4.44e-51 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MHPNILHJ_01635 5.36e-308 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MHPNILHJ_01636 2.51e-199 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MHPNILHJ_01637 2.58e-85 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MHPNILHJ_01638 5.53e-87 yqhY - - S - - - protein conserved in bacteria
MHPNILHJ_01639 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
MHPNILHJ_01640 2.59e-83 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MHPNILHJ_01641 1.88e-86 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
MHPNILHJ_01642 1.3e-145 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
MHPNILHJ_01643 1.74e-129 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
MHPNILHJ_01644 3.02e-260 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
MHPNILHJ_01645 5.28e-55 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
MHPNILHJ_01646 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
MHPNILHJ_01647 2.23e-108 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
MHPNILHJ_01648 7.55e-213 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
MHPNILHJ_01649 1.64e-48 yqhV - - S - - - Protein of unknown function (DUF2619)
MHPNILHJ_01650 9.69e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MHPNILHJ_01651 2.75e-245 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
MHPNILHJ_01652 2.13e-113 yqhR - - S - - - Conserved membrane protein YqhR
MHPNILHJ_01653 1.12e-215 yqhQ - - S - - - Protein of unknown function (DUF1385)
MHPNILHJ_01654 8.59e-80 yqhP - - - - - - -
MHPNILHJ_01655 2.51e-203 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
MHPNILHJ_01656 1.14e-96 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
MHPNILHJ_01657 1.25e-201 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
MHPNILHJ_01658 2.33e-84 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
MHPNILHJ_01659 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MHPNILHJ_01660 2.14e-313 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MHPNILHJ_01661 7.69e-254 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
MHPNILHJ_01662 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
MHPNILHJ_01663 8.42e-193 yqhG - - S - - - Bacterial protein YqhG of unknown function
MHPNILHJ_01664 1.3e-29 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
MHPNILHJ_01665 2.27e-71 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
MHPNILHJ_01666 8.28e-178 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
MHPNILHJ_01667 5.48e-95 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
MHPNILHJ_01668 7.32e-144 yqxM - - - ko:K19433 - ko00000 -
MHPNILHJ_01669 3.98e-70 yqzG - - S - - - Protein of unknown function (DUF3889)
MHPNILHJ_01670 9.56e-35 yqzE - - S - - - YqzE-like protein
MHPNILHJ_01671 8.44e-75 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
MHPNILHJ_01672 2.45e-28 comGF - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
MHPNILHJ_01673 1.56e-26 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
MHPNILHJ_01674 3.1e-91 - - - NU ko:K02246,ko:K08084 - ko00000,ko00002,ko02044 Tfp pilus assembly protein FimT
MHPNILHJ_01675 1.5e-64 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
MHPNILHJ_01676 5.79e-227 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
MHPNILHJ_01677 5.85e-253 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MHPNILHJ_01678 1.34e-231 yqxL - - P - - - Mg2 transporter protein
MHPNILHJ_01679 2.13e-294 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
MHPNILHJ_01680 3.19e-178 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MHPNILHJ_01682 4.34e-82 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
MHPNILHJ_01683 4.19e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
MHPNILHJ_01684 2e-156 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
MHPNILHJ_01685 1.07e-28 yqgW - - S - - - Protein of unknown function (DUF2759)
MHPNILHJ_01686 2.02e-63 dglA - - S - - - Thiamine-binding protein
MHPNILHJ_01687 1.06e-48 yqgU - - - - - - -
MHPNILHJ_01688 9.93e-162 yqgU - - - - - - -
MHPNILHJ_01689 1.33e-256 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
MHPNILHJ_01690 1.18e-227 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
MHPNILHJ_01691 1.87e-37 yqgQ - - S - - - Protein conserved in bacteria
MHPNILHJ_01692 2.58e-269 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
MHPNILHJ_01693 5.38e-11 yqgO - - - - - - -
MHPNILHJ_01694 7.01e-116 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MHPNILHJ_01695 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
MHPNILHJ_01696 3.42e-68 yqzD - - - - - - -
MHPNILHJ_01697 1.97e-96 yqzC - - S - - - Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MHPNILHJ_01698 2.71e-187 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MHPNILHJ_01699 2.99e-179 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MHPNILHJ_01700 1.88e-195 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
MHPNILHJ_01701 1.75e-203 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
MHPNILHJ_01702 8.72e-204 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
MHPNILHJ_01703 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
MHPNILHJ_01704 5.94e-283 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
MHPNILHJ_01705 4.22e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
MHPNILHJ_01706 7.59e-97 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
MHPNILHJ_01707 2.44e-164 yqgB - - S - - - Protein of unknown function (DUF1189)
MHPNILHJ_01708 5.95e-59 yqfZ - - M ko:K06417 - ko00000 LysM domain
MHPNILHJ_01709 2.3e-255 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MHPNILHJ_01710 3.9e-79 yqfX - - S - - - membrane
MHPNILHJ_01711 3.23e-139 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
MHPNILHJ_01712 2.63e-99 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
MHPNILHJ_01713 2.47e-195 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
MHPNILHJ_01714 2.48e-48 yqfT - - S - - - Protein of unknown function (DUF2624)
MHPNILHJ_01715 5.3e-208 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MHPNILHJ_01716 3.91e-304 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MHPNILHJ_01717 7.12e-57 yqfQ - - S - - - YqfQ-like protein
MHPNILHJ_01718 4.12e-225 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MHPNILHJ_01719 2.97e-266 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MHPNILHJ_01720 1.65e-159 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
MHPNILHJ_01721 7.67e-80 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
MHPNILHJ_01722 8e-255 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MHPNILHJ_01723 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MHPNILHJ_01724 9.16e-111 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
MHPNILHJ_01725 1.75e-188 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MHPNILHJ_01726 3.41e-144 ccpN - - K - - - CBS domain
MHPNILHJ_01727 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
MHPNILHJ_01728 2.03e-220 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
MHPNILHJ_01729 2.31e-181 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
MHPNILHJ_01730 6e-24 - - - S - - - YqzL-like protein
MHPNILHJ_01731 2.01e-214 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MHPNILHJ_01732 1.92e-92 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
MHPNILHJ_01733 8.76e-82 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
MHPNILHJ_01734 2.91e-104 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MHPNILHJ_01735 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
MHPNILHJ_01736 4.78e-222 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
MHPNILHJ_01737 7.99e-273 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
MHPNILHJ_01738 3.57e-61 yqfC - - S - - - sporulation protein YqfC
MHPNILHJ_01739 1.28e-48 yqfB - - - - - - -
MHPNILHJ_01740 1.22e-186 yqfA - - S - - - UPF0365 protein
MHPNILHJ_01741 7.88e-288 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
MHPNILHJ_01742 7.84e-91 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
MHPNILHJ_01743 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
MHPNILHJ_01744 1.4e-194 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
MHPNILHJ_01745 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
MHPNILHJ_01746 1.14e-177 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MHPNILHJ_01747 7.67e-224 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
MHPNILHJ_01748 4.72e-264 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MHPNILHJ_01749 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
MHPNILHJ_01750 2.08e-106 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MHPNILHJ_01751 1.3e-238 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MHPNILHJ_01752 1.93e-265 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
MHPNILHJ_01753 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MHPNILHJ_01754 1.17e-68 yqxA - - S - - - Protein of unknown function (DUF3679)
MHPNILHJ_01755 2.14e-278 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
MHPNILHJ_01756 9.8e-258 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MHPNILHJ_01757 1.91e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
MHPNILHJ_01758 8.29e-229 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
MHPNILHJ_01759 7.73e-22 - - - S - - - YqzM-like protein
MHPNILHJ_01760 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
MHPNILHJ_01761 8.94e-135 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
MHPNILHJ_01762 3.77e-123 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
MHPNILHJ_01763 1.74e-185 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MHPNILHJ_01764 4.47e-174 yqeM - - Q - - - Methyltransferase
MHPNILHJ_01765 1.1e-78 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MHPNILHJ_01766 1.13e-131 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
MHPNILHJ_01767 8.59e-133 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MHPNILHJ_01768 8.62e-59 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
MHPNILHJ_01769 5.24e-195 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MHPNILHJ_01770 1.08e-269 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
MHPNILHJ_01771 7.28e-122 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
MHPNILHJ_01773 7.74e-174 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
MHPNILHJ_01774 2.3e-171 pdaC 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
MHPNILHJ_01775 2.21e-140 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
MHPNILHJ_01776 7.69e-134 yqeD - - S - - - SNARE associated Golgi protein
MHPNILHJ_01778 2.92e-254 - - - EGP - - - Transmembrane secretion effector
MHPNILHJ_01779 1.17e-158 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHPNILHJ_01780 1.25e-202 - - - S - - - Carbohydrate esterase, sialic acid-specific acetylesterase
MHPNILHJ_01781 7.88e-116 - - - K - - - Transcriptional regulator PadR-like family
MHPNILHJ_01782 3.71e-126 yqaC - - F - - - adenylate kinase activity
MHPNILHJ_01783 6.92e-35 - - - K - - - acetyltransferase
MHPNILHJ_01784 7.94e-282 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 COG0477 Permeases of the major facilitator superfamily
MHPNILHJ_01785 2.45e-114 - - - S - - - DinB family
MHPNILHJ_01786 5.58e-179 supH - - S - - - hydrolase
MHPNILHJ_01787 2.86e-178 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
MHPNILHJ_01788 7.87e-157 - - - K - - - Helix-turn-helix domain, rpiR family
MHPNILHJ_01789 5.34e-217 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
MHPNILHJ_01790 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MHPNILHJ_01791 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
MHPNILHJ_01792 1.31e-212 romA - - S - - - Beta-lactamase superfamily domain
MHPNILHJ_01793 1.26e-95 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MHPNILHJ_01794 3.47e-206 yybE - - K - - - Transcriptional regulator
MHPNILHJ_01795 8.7e-262 yybF1 - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
MHPNILHJ_01796 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
MHPNILHJ_01797 2.09e-124 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
MHPNILHJ_01798 2.19e-112 yrhH - - Q - - - methyltransferase
MHPNILHJ_01799 2.37e-07 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
MHPNILHJ_01800 1.48e-178 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
MHPNILHJ_01801 4.41e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
MHPNILHJ_01802 0.0 yrhE 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
MHPNILHJ_01803 4.38e-102 yrhD - - S - - - Protein of unknown function (DUF1641)
MHPNILHJ_01804 9.51e-47 yrhC - - S - - - YrhC-like protein
MHPNILHJ_01805 6.51e-269 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
MHPNILHJ_01806 8.52e-212 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
MHPNILHJ_01807 6.59e-160 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MHPNILHJ_01808 3.7e-148 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
MHPNILHJ_01809 2.53e-38 yrzA - - S - - - Protein of unknown function (DUF2536)
MHPNILHJ_01810 6.53e-120 yrrS - - S - - - Protein of unknown function (DUF1510)
MHPNILHJ_01811 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
MHPNILHJ_01812 5.41e-100 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MHPNILHJ_01813 2.61e-147 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
MHPNILHJ_01814 1.8e-310 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
MHPNILHJ_01815 4.25e-220 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
MHPNILHJ_01816 3.4e-146 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
MHPNILHJ_01817 1.71e-244 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MHPNILHJ_01818 7.2e-61 yrzB - - S - - - Belongs to the UPF0473 family
MHPNILHJ_01819 1.11e-92 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MHPNILHJ_01820 1.29e-54 yrzL - - S - - - Belongs to the UPF0297 family
MHPNILHJ_01821 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MHPNILHJ_01822 1.39e-222 yrrI - - S - - - AI-2E family transporter
MHPNILHJ_01823 1.67e-163 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
MHPNILHJ_01824 1.67e-184 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
MHPNILHJ_01825 7.62e-138 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MHPNILHJ_01826 1.21e-135 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MHPNILHJ_01827 6.52e-13 - - - S - - - Protein of unknown function (DUF3918)
MHPNILHJ_01828 8.4e-42 yrzR - - - - - - -
MHPNILHJ_01829 7.39e-100 yrrD - - S - - - protein conserved in bacteria
MHPNILHJ_01830 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MHPNILHJ_01831 1.12e-23 yrrB - - S - - - COG0457 FOG TPR repeat
MHPNILHJ_01832 1.89e-277 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MHPNILHJ_01833 2.35e-266 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
MHPNILHJ_01834 3.74e-83 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
MHPNILHJ_01835 4.18e-300 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
MHPNILHJ_01836 1.68e-178 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
MHPNILHJ_01837 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MHPNILHJ_01838 7.9e-306 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
MHPNILHJ_01841 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
MHPNILHJ_01842 4.07e-97 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MHPNILHJ_01843 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MHPNILHJ_01844 1.71e-116 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MHPNILHJ_01845 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
MHPNILHJ_01846 7.18e-59 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
MHPNILHJ_01847 3.74e-104 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
MHPNILHJ_01848 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MHPNILHJ_01849 2.26e-64 yrzD - - S - - - Post-transcriptional regulator
MHPNILHJ_01850 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MHPNILHJ_01851 1.16e-133 yrbG - - S - - - membrane
MHPNILHJ_01852 3.7e-80 yrzE - - S - - - Protein of unknown function (DUF3792)
MHPNILHJ_01853 1.03e-50 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
MHPNILHJ_01854 3.9e-291 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MHPNILHJ_01855 7.88e-244 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MHPNILHJ_01856 3.4e-29 yrzS - - S - - - Protein of unknown function (DUF2905)
MHPNILHJ_01857 6.61e-232 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MHPNILHJ_01858 8.13e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MHPNILHJ_01859 1.93e-117 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
MHPNILHJ_01861 1.26e-60 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MHPNILHJ_01862 2.07e-217 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
MHPNILHJ_01863 2.53e-264 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MHPNILHJ_01864 6.72e-183 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
MHPNILHJ_01865 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
MHPNILHJ_01866 8.23e-269 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
MHPNILHJ_01867 1.49e-115 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
MHPNILHJ_01868 4.34e-201 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
MHPNILHJ_01869 5.94e-95 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
MHPNILHJ_01870 2.37e-309 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MHPNILHJ_01871 2.87e-137 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
MHPNILHJ_01872 7.74e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
MHPNILHJ_01873 5.78e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
MHPNILHJ_01874 1.28e-65 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
MHPNILHJ_01875 3.7e-199 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
MHPNILHJ_01876 2.65e-177 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
MHPNILHJ_01877 1.61e-183 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
MHPNILHJ_01878 1.61e-153 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MHPNILHJ_01879 3.98e-107 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
MHPNILHJ_01880 2.51e-201 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
MHPNILHJ_01881 2.91e-232 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
MHPNILHJ_01882 1.19e-162 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
MHPNILHJ_01883 1.6e-128 maf - - D ko:K06287 - ko00000 septum formation protein Maf
MHPNILHJ_01884 2.51e-192 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
MHPNILHJ_01885 1.4e-159 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
MHPNILHJ_01886 2.79e-293 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
MHPNILHJ_01887 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MHPNILHJ_01888 3.61e-34 - - - - - - - -
MHPNILHJ_01889 3.17e-234 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MHPNILHJ_01890 5.07e-232 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
MHPNILHJ_01891 4.08e-306 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
MHPNILHJ_01892 1.7e-234 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
MHPNILHJ_01893 4.99e-176 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
MHPNILHJ_01894 6.05e-222 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
MHPNILHJ_01895 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
MHPNILHJ_01896 2.79e-311 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MHPNILHJ_01897 3.63e-110 ysxD - - - - - - -
MHPNILHJ_01898 8.88e-138 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
MHPNILHJ_01899 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MHPNILHJ_01900 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
MHPNILHJ_01901 2.7e-295 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MHPNILHJ_01902 1.21e-284 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MHPNILHJ_01903 6.44e-239 ysoA - - H - - - Tetratricopeptide repeat
MHPNILHJ_01904 1.04e-147 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MHPNILHJ_01905 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MHPNILHJ_01906 2.66e-249 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MHPNILHJ_01907 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MHPNILHJ_01908 6.75e-245 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MHPNILHJ_01909 1.45e-109 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
MHPNILHJ_01910 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
MHPNILHJ_01915 8.81e-110 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
MHPNILHJ_01916 3.07e-129 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MHPNILHJ_01917 2.38e-169 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MHPNILHJ_01918 1.05e-253 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
MHPNILHJ_01919 1.29e-193 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
MHPNILHJ_01920 7.32e-95 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
MHPNILHJ_01921 6.32e-42 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
MHPNILHJ_01922 8.26e-96 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
MHPNILHJ_01923 1.77e-188 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
MHPNILHJ_01924 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
MHPNILHJ_01925 2.73e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
MHPNILHJ_01926 9.97e-103 yslB - - S - - - Protein of unknown function (DUF2507)
MHPNILHJ_01927 9.22e-270 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
MHPNILHJ_01928 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MHPNILHJ_01929 1.6e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
MHPNILHJ_01930 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
MHPNILHJ_01931 4.79e-225 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
MHPNILHJ_01932 5.83e-176 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
MHPNILHJ_01933 7.29e-171 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
MHPNILHJ_01934 1.78e-133 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
MHPNILHJ_01935 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MHPNILHJ_01936 7.35e-104 ywbB - - S - - - Protein of unknown function (DUF2711)
MHPNILHJ_01937 3.09e-88 yshE - - S ko:K08989 - ko00000 membrane
MHPNILHJ_01938 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MHPNILHJ_01939 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
MHPNILHJ_01940 2.02e-107 yshB - - S - - - membrane protein, required for colicin V production
MHPNILHJ_01941 4.23e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MHPNILHJ_01942 1.64e-210 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MHPNILHJ_01943 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MHPNILHJ_01944 1.27e-248 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MHPNILHJ_01945 1.94e-165 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MHPNILHJ_01946 8.83e-43 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
MHPNILHJ_01947 5.97e-244 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
MHPNILHJ_01948 0.0 - 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD binding domain
MHPNILHJ_01949 6.09e-310 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
MHPNILHJ_01950 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
MHPNILHJ_01951 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
MHPNILHJ_01952 1.27e-186 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
MHPNILHJ_01953 8.11e-211 araP - - P ko:K10189,ko:K10241,ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PFAM binding-protein-dependent transport systems inner membrane component
MHPNILHJ_01954 2.69e-312 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
MHPNILHJ_01955 2.36e-269 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
MHPNILHJ_01956 1.33e-175 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
MHPNILHJ_01957 2.82e-169 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
MHPNILHJ_01958 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
MHPNILHJ_01959 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
MHPNILHJ_01960 4.34e-235 abnA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
MHPNILHJ_01961 1.52e-262 ysdC - - G - - - COG1363 Cellulase M and related proteins
MHPNILHJ_01962 4.11e-82 ysdB - - S - - - Sigma-w pathway protein YsdB
MHPNILHJ_01963 1.7e-50 ysdA - - S - - - Membrane
MHPNILHJ_01964 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MHPNILHJ_01965 1.95e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
MHPNILHJ_01966 1.81e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MHPNILHJ_01967 1.21e-144 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
MHPNILHJ_01968 3.04e-64 - - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 effector of murein hydrolase LrgA
MHPNILHJ_01969 8.26e-165 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
MHPNILHJ_01970 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MHPNILHJ_01971 2.22e-188 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
MHPNILHJ_01972 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MHPNILHJ_01973 6.12e-192 ytxC - - S - - - YtxC-like family
MHPNILHJ_01974 1.43e-136 ytxB - - S - - - SNARE associated Golgi protein
MHPNILHJ_01975 2.64e-215 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
MHPNILHJ_01976 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
MHPNILHJ_01977 5.95e-106 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MHPNILHJ_01978 1.82e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MHPNILHJ_01979 4.24e-247 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MHPNILHJ_01980 7.74e-86 ytcD - - K - - - Transcriptional regulator
MHPNILHJ_01981 3.31e-251 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
MHPNILHJ_01982 4.68e-198 ytbE - - S - - - reductase
MHPNILHJ_01983 3.15e-123 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MHPNILHJ_01984 4.52e-135 ytaF - - P - - - Probably functions as a manganese efflux pump
MHPNILHJ_01985 2.14e-197 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MHPNILHJ_01986 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MHPNILHJ_01987 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
MHPNILHJ_01988 2.29e-164 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHPNILHJ_01989 3.62e-218 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
MHPNILHJ_01990 1.54e-307 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
MHPNILHJ_01991 8.21e-268 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
MHPNILHJ_01992 1.14e-95 ytwI - - S - - - membrane
MHPNILHJ_01993 8.18e-247 ytvI - - S - - - sporulation integral membrane protein YtvI
MHPNILHJ_01994 1.34e-81 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
MHPNILHJ_01995 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
MHPNILHJ_01996 1.33e-228 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MHPNILHJ_01997 3.28e-232 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
MHPNILHJ_01998 2.08e-206 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MHPNILHJ_01999 1.92e-283 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
MHPNILHJ_02000 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
MHPNILHJ_02001 1.12e-71 ytrH - - S - - - Sporulation protein YtrH
MHPNILHJ_02002 3.08e-113 ytrI - - - - - - -
MHPNILHJ_02003 1.17e-30 - - - - - - - -
MHPNILHJ_02004 7.37e-223 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
MHPNILHJ_02005 3.44e-60 ytpI - - S - - - YtpI-like protein
MHPNILHJ_02006 3.87e-303 ytoI - - K - - - transcriptional regulator containing CBS domains
MHPNILHJ_02007 2.31e-163 ytkL - - S - - - Belongs to the UPF0173 family
MHPNILHJ_02008 1.33e-180 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHPNILHJ_02010 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
MHPNILHJ_02011 8.67e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
MHPNILHJ_02012 1.64e-114 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
MHPNILHJ_02013 2.6e-278 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MHPNILHJ_02014 4.08e-223 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
MHPNILHJ_02015 1.12e-115 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MHPNILHJ_02016 1.37e-99 ytfJ - - S - - - Sporulation protein YtfJ
MHPNILHJ_02017 3.61e-147 ytfI - - S - - - Protein of unknown function (DUF2953)
MHPNILHJ_02018 1.31e-103 yteJ - - S - - - RDD family
MHPNILHJ_02019 1.88e-227 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
MHPNILHJ_02020 1.23e-191 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MHPNILHJ_02021 0.0 ytcJ - - S - - - amidohydrolase
MHPNILHJ_02022 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MHPNILHJ_02023 4.15e-42 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
MHPNILHJ_02024 1.06e-280 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MHPNILHJ_02025 3.99e-259 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
MHPNILHJ_02026 4.41e-305 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
MHPNILHJ_02027 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MHPNILHJ_02028 3.79e-183 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
MHPNILHJ_02029 2.22e-137 yttP - - K - - - Transcriptional regulator
MHPNILHJ_02030 2.38e-109 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
MHPNILHJ_02031 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
MHPNILHJ_02032 5.75e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MHPNILHJ_02033 2.12e-273 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MHPNILHJ_02036 0.000125 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
MHPNILHJ_02038 1.52e-161 - - - E - - - GDSL-like Lipase/Acylhydrolase family
MHPNILHJ_02039 6.5e-189 - - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MHPNILHJ_02040 1.06e-188 - - - K - - - Transcriptional regulator
MHPNILHJ_02041 7.21e-154 ygaZ - - E - - - AzlC protein
MHPNILHJ_02042 7.23e-63 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
MHPNILHJ_02043 1.41e-302 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MHPNILHJ_02044 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MHPNILHJ_02045 3.32e-154 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
MHPNILHJ_02046 1.67e-138 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
MHPNILHJ_02047 8.46e-285 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
MHPNILHJ_02048 2.17e-126 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
MHPNILHJ_02049 2.47e-184 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
MHPNILHJ_02050 7.72e-231 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
MHPNILHJ_02051 1.8e-248 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
MHPNILHJ_02052 8.39e-58 ytxJ - - O - - - Protein of unknown function (DUF2847)
MHPNILHJ_02053 1.83e-30 ytxH - - S - - - COG4980 Gas vesicle protein
MHPNILHJ_02054 2.16e-25 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MHPNILHJ_02055 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
MHPNILHJ_02056 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
MHPNILHJ_02057 1.15e-136 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MHPNILHJ_02058 1.1e-186 ytpQ - - S - - - Belongs to the UPF0354 family
MHPNILHJ_02059 2.23e-75 ytpP - - CO - - - Thioredoxin
MHPNILHJ_02060 9.21e-99 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
MHPNILHJ_02061 8.38e-258 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
MHPNILHJ_02062 9.96e-69 ytzB - - S - - - small secreted protein
MHPNILHJ_02063 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
MHPNILHJ_02064 1.41e-204 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
MHPNILHJ_02065 4.34e-158 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MHPNILHJ_02066 4.54e-59 ytzH - - S - - - YtzH-like protein
MHPNILHJ_02067 3.42e-198 ytmP - - M - - - Phosphotransferase
MHPNILHJ_02068 1.86e-214 ytlR - - I - - - Diacylglycerol kinase catalytic domain
MHPNILHJ_02069 2.99e-200 ytlQ - - - - - - -
MHPNILHJ_02070 2.04e-128 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MHPNILHJ_02071 4.05e-214 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
MHPNILHJ_02072 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
MHPNILHJ_02073 3.89e-286 pbuO - - S ko:K06901 - ko00000,ko02000 permease
MHPNILHJ_02074 1.21e-251 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
MHPNILHJ_02075 1.92e-149 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MHPNILHJ_02076 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
MHPNILHJ_02077 4.25e-160 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MHPNILHJ_02078 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MHPNILHJ_02079 2.31e-293 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
MHPNILHJ_02080 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
MHPNILHJ_02081 3.57e-35 yteV - - S - - - Sporulation protein Cse60
MHPNILHJ_02082 3.97e-232 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
MHPNILHJ_02083 3.41e-296 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
MHPNILHJ_02084 6.99e-212 - - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MHPNILHJ_02085 1.37e-182 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
MHPNILHJ_02086 2.49e-313 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
MHPNILHJ_02087 6.31e-96 - - - M - - - Acetyltransferase (GNAT) domain
MHPNILHJ_02088 8.6e-69 ytwF - - P - - - Sulfurtransferase
MHPNILHJ_02089 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
MHPNILHJ_02090 7.19e-69 ytvB - - S - - - Protein of unknown function (DUF4257)
MHPNILHJ_02091 1.79e-172 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
MHPNILHJ_02092 2.16e-265 yttB - - EGP - - - Major facilitator superfamily
MHPNILHJ_02093 1.46e-151 ywaF - - S - - - Integral membrane protein
MHPNILHJ_02094 0.0 bceB - - V ko:K02004,ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
MHPNILHJ_02095 7.67e-171 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
MHPNILHJ_02096 2.32e-216 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
MHPNILHJ_02097 5.19e-157 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHPNILHJ_02098 3.54e-258 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
MHPNILHJ_02099 7.08e-160 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MHPNILHJ_02100 1.47e-190 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
MHPNILHJ_02101 2.63e-203 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
MHPNILHJ_02102 2.23e-215 ytrC - - S ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
MHPNILHJ_02103 9.08e-202 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MHPNILHJ_02104 6.32e-86 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
MHPNILHJ_02106 2.89e-52 ytzC - - S - - - Protein of unknown function (DUF2524)
MHPNILHJ_02107 6.73e-244 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
MHPNILHJ_02108 4.07e-133 ytqB - - J - - - Putative rRNA methylase
MHPNILHJ_02110 2.17e-266 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
MHPNILHJ_02111 6.67e-192 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
MHPNILHJ_02112 7.46e-80 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MHPNILHJ_02113 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
MHPNILHJ_02114 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
MHPNILHJ_02115 7.88e-287 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MHPNILHJ_02116 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MHPNILHJ_02117 1.65e-51 ytmB - - S - - - Protein of unknown function (DUF2584)
MHPNILHJ_02118 6.15e-187 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
MHPNILHJ_02119 6.07e-228 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
MHPNILHJ_02120 1.38e-180 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MHPNILHJ_02121 3.42e-170 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MHPNILHJ_02122 5.86e-114 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
MHPNILHJ_02123 1.67e-77 ytkC - - S - - - Bacteriophage holin family
MHPNILHJ_02124 3e-98 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
MHPNILHJ_02126 9.99e-98 ytkA - - S - - - YtkA-like
MHPNILHJ_02127 5.89e-113 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MHPNILHJ_02128 5.71e-52 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
MHPNILHJ_02129 4.26e-133 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
MHPNILHJ_02130 7.13e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
MHPNILHJ_02131 6.36e-313 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
MHPNILHJ_02132 9.63e-230 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
MHPNILHJ_02133 3.88e-34 - - - S - - - Domain of Unknown Function (DUF1540)
MHPNILHJ_02134 4.21e-265 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
MHPNILHJ_02135 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MHPNILHJ_02136 7.22e-198 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MHPNILHJ_02137 2.39e-188 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
MHPNILHJ_02138 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MHPNILHJ_02139 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
MHPNILHJ_02140 8.57e-160 yteA - - T - - - COG1734 DnaK suppressor protein
MHPNILHJ_02141 5.18e-93 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
MHPNILHJ_02154 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MHPNILHJ_02155 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MHPNILHJ_02156 6.18e-52 yaaB - - S - - - Domain of unknown function (DUF370)
MHPNILHJ_02157 1.07e-262 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MHPNILHJ_02158 3.19e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
MHPNILHJ_02159 2.83e-262 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MHPNILHJ_02160 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MHPNILHJ_02161 1.84e-67 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MHPNILHJ_02162 6.08e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MHPNILHJ_02163 7.08e-137 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
MHPNILHJ_02164 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MHPNILHJ_02165 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MHPNILHJ_02166 2.56e-161 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
MHPNILHJ_02167 1.1e-193 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
MHPNILHJ_02168 2.38e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
MHPNILHJ_02169 6.79e-188 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
MHPNILHJ_02170 1.3e-139 yyaC - - S - - - Sporulation protein YyaC
MHPNILHJ_02171 2.63e-74 yhhY - - K - - - FR47-like protein
MHPNILHJ_02172 5.45e-215 yyaD - - S - - - Membrane
MHPNILHJ_02173 1.82e-45 yyzM - - S - - - protein conserved in bacteria
MHPNILHJ_02174 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MHPNILHJ_02175 6.32e-253 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MHPNILHJ_02176 3.39e-60 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
MHPNILHJ_02177 1.37e-98 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MHPNILHJ_02178 1.11e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MHPNILHJ_02179 3.59e-123 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
MHPNILHJ_02180 6.58e-112 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MHPNILHJ_02181 2.49e-179 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
MHPNILHJ_02182 7.31e-218 ccpB - - K - - - Transcriptional regulator
MHPNILHJ_02183 9.47e-86 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MHPNILHJ_02184 2.8e-311 - - - G ko:K08369 - ko00000,ko02000 Sugar (and other) transporter
MHPNILHJ_02185 1.66e-193 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
MHPNILHJ_02186 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
MHPNILHJ_02187 7.54e-124 - - - L - - - Reverse transcriptase (RNA-dependent DNA polymerase)
MHPNILHJ_02188 6.96e-33 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
MHPNILHJ_02189 2.31e-174 - - - EG - - - EamA-like transporter family
MHPNILHJ_02190 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MHPNILHJ_02191 7.09e-101 - - - S - - - DinB superfamily
MHPNILHJ_02192 1.65e-91 yjcF - - S - - - Acetyltransferase (GNAT) domain
MHPNILHJ_02193 1.78e-97 yybA - - K - - - transcriptional
MHPNILHJ_02194 7.02e-190 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
MHPNILHJ_02195 1.79e-85 - - - K - - - Winged helix DNA-binding domain
MHPNILHJ_02196 1.56e-144 ydgI - - C - - - nitroreductase
MHPNILHJ_02197 3.76e-72 ypaA - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
MHPNILHJ_02198 4.82e-185 - - - G - - - Major Facilitator Superfamily
MHPNILHJ_02199 6.2e-112 - - - S - - - PFAM DinB family protein
MHPNILHJ_02200 4.59e-143 - - - K - - - FCD domain
MHPNILHJ_02201 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
MHPNILHJ_02202 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
MHPNILHJ_02203 1.8e-191 ypaH - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MHPNILHJ_02204 4.01e-209 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
MHPNILHJ_02205 2.54e-84 yybR - - K - - - Transcriptional regulator
MHPNILHJ_02206 9.65e-105 cotF - - M ko:K06329 - ko00000 Spore coat protein
MHPNILHJ_02208 6.36e-191 yybS - - S - - - membrane
MHPNILHJ_02209 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
MHPNILHJ_02210 1.85e-94 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
MHPNILHJ_02211 1.92e-106 - - - KLT - - - COG0515 Serine threonine protein kinase
MHPNILHJ_02212 3.43e-154 - - - S - - - GlcNAc-PI de-N-acetylase
MHPNILHJ_02213 1.37e-279 - - - M - - - Glycosyltransferase Family 4
MHPNILHJ_02214 2.11e-293 - - - S - - - Carbamoyl-phosphate synthase L chain, ATP binding domain
MHPNILHJ_02215 5.54e-244 - - - S - - - Ecdysteroid kinase
MHPNILHJ_02216 3.86e-271 - - - M - - - Glycosyltransferase Family 4
MHPNILHJ_02217 3.6e-25 yycC - - K - - - YycC-like protein
MHPNILHJ_02219 9e-38 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
MHPNILHJ_02220 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
MHPNILHJ_02221 1.57e-92 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MHPNILHJ_02222 1.83e-314 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MHPNILHJ_02227 1.51e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHPNILHJ_02228 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MHPNILHJ_02229 0.0 yycH - - S - - - protein conserved in bacteria
MHPNILHJ_02230 9e-191 yycI - - S - - - protein conserved in bacteria
MHPNILHJ_02231 4.01e-191 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
MHPNILHJ_02232 1.37e-270 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MHPNILHJ_02233 6.88e-86 - - - S - - - Peptidase propeptide and YPEB domain
MHPNILHJ_02234 3.35e-119 - - - K ko:K02483 - ko00000,ko02022 PFAM response regulator receiver
MHPNILHJ_02235 5.41e-310 - 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
MHPNILHJ_02236 8.24e-255 - - - S - - - Major Facilitator Superfamily
MHPNILHJ_02237 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
MHPNILHJ_02238 3.82e-57 sdpR - - K - - - transcriptional
MHPNILHJ_02239 1.26e-85 yvaZ - - S - - - Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
MHPNILHJ_02240 1.75e-295 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
MHPNILHJ_02241 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
MHPNILHJ_02242 7.27e-210 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
MHPNILHJ_02243 2.05e-256 - - - S ko:K06361,ko:K06365,ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
MHPNILHJ_02245 2.13e-106 yycN - - K - - - Acetyltransferase
MHPNILHJ_02246 3.13e-226 - - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
MHPNILHJ_02247 1.54e-167 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MHPNILHJ_02248 5.96e-264 yycP - - - - - - -
MHPNILHJ_02252 1.01e-105 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MHPNILHJ_02253 0.0 - - - L - - - AAA ATPase domain
MHPNILHJ_02254 9.5e-40 - - - L - - - AAA domain
MHPNILHJ_02255 7.74e-48 - - - L - - - AAA domain
MHPNILHJ_02256 1.41e-245 - - - L - - - AAA domain
MHPNILHJ_02257 6.58e-27 - - - - - - - -
MHPNILHJ_02258 1.86e-208 - - - S - - - Fusaric acid resistance protein-like
MHPNILHJ_02259 5.41e-213 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MHPNILHJ_02260 7.29e-105 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
MHPNILHJ_02261 0.0 - - - C - - - COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
MHPNILHJ_02262 2.98e-185 - - - C - - - COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
MHPNILHJ_02263 9.27e-101 pucE 1.2.5.3 - C ko:K03518 - ko00000,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
MHPNILHJ_02264 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
MHPNILHJ_02265 1.81e-97 yjhE - - S - - - Phage tail protein
MHPNILHJ_02266 8.87e-97 - - - K - - - Integron-associated effector binding protein
MHPNILHJ_02267 2.75e-201 - - - K - - - helix_turn_helix, Deoxyribose operon repressor
MHPNILHJ_02268 1.78e-301 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
MHPNILHJ_02269 7.69e-229 mrjp - - G - - - Major royal jelly protein
MHPNILHJ_02270 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
MHPNILHJ_02271 1.55e-134 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
MHPNILHJ_02272 3.12e-152 - - - E - - - Ring-cleavage extradiol dioxygenase
MHPNILHJ_02273 3.67e-86 yxaI - - S - - - membrane protein domain
MHPNILHJ_02274 9.97e-252 - - - EGP - - - Major Facilitator Superfamily
MHPNILHJ_02275 2.01e-66 arsR3 - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MHPNILHJ_02276 8.25e-75 - - - S - - - Family of unknown function (DUF5391)
MHPNILHJ_02277 2.12e-185 yxaL - - S - - - PQQ-like domain
MHPNILHJ_02278 4.85e-313 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
MHPNILHJ_02279 1.78e-264 yxbF - - K - - - Bacterial regulatory proteins, tetR family
MHPNILHJ_02280 1.73e-246 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
MHPNILHJ_02281 1.35e-244 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MHPNILHJ_02282 2.06e-129 desR - - T ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MHPNILHJ_02283 6.33e-188 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
MHPNILHJ_02284 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
MHPNILHJ_02285 2.13e-311 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MHPNILHJ_02286 1.26e-217 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
MHPNILHJ_02287 1.75e-174 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
MHPNILHJ_02288 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MHPNILHJ_02289 1.11e-196 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
MHPNILHJ_02290 3.5e-225 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
MHPNILHJ_02291 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
MHPNILHJ_02292 1.73e-218 iolE 4.2.1.44 - H ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
MHPNILHJ_02293 2.76e-289 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
MHPNILHJ_02294 2.36e-246 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
MHPNILHJ_02295 4.92e-209 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
MHPNILHJ_02296 4.68e-198 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
MHPNILHJ_02297 1.61e-194 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
MHPNILHJ_02298 6.33e-157 yxdJ - - T ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHPNILHJ_02299 9.27e-223 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MHPNILHJ_02300 7.1e-177 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MHPNILHJ_02301 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
MHPNILHJ_02302 2.25e-72 yxeA - - S - - - Protein of unknown function (DUF1093)
MHPNILHJ_02303 6.74e-218 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
MHPNILHJ_02304 4.86e-47 - - - - - - - -
MHPNILHJ_02305 9.67e-33 yxeD - - - - - - -
MHPNILHJ_02307 9.45e-26 yxeE - - - - - - -
MHPNILHJ_02310 1.75e-188 yxeH - - S - - - hydrolases of the HAD superfamily
MHPNILHJ_02311 9.22e-217 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MHPNILHJ_02312 4.09e-145 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MHPNILHJ_02313 2.33e-264 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MHPNILHJ_02314 2.59e-295 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
MHPNILHJ_02315 0.0 hutM - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
MHPNILHJ_02316 6.73e-216 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
MHPNILHJ_02317 1.88e-291 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
MHPNILHJ_02318 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MHPNILHJ_02319 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
MHPNILHJ_02320 4.06e-102 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
MHPNILHJ_02321 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
MHPNILHJ_02322 3.56e-147 - - - S - - - AIPR protein
MHPNILHJ_02323 7.27e-51 - - - S - - - AIPR protein
MHPNILHJ_02324 7.49e-103 - - - S - - - Putative PD-(D/E)XK family member, (DUF4420)
MHPNILHJ_02325 1.59e-12 - - - L - - - Z1 domain
MHPNILHJ_02326 7.34e-294 - - - L - - - Z1 domain
MHPNILHJ_02327 3.55e-204 - - - L - - - Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
MHPNILHJ_02328 8.04e-176 - 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 C-5 cytosine-specific DNA methylase
MHPNILHJ_02329 1.51e-61 - - - L ko:K07458 - ko00000,ko01000,ko03400 May nick specific sequences that contain T G mispairs resulting from m5C-deamination
MHPNILHJ_02330 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MHPNILHJ_02331 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MHPNILHJ_02332 2.44e-94 yxiE - - T - - - Belongs to the universal stress protein A family
MHPNILHJ_02333 7.42e-202 yxxF - - EG - - - EamA-like transporter family
MHPNILHJ_02334 4.8e-251 pelB 4.2.2.10, 4.2.2.2 - G ko:K01728,ko:K01732 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
MHPNILHJ_02336 9.79e-75 yxxG - - - - - - -
MHPNILHJ_02337 2.91e-85 yxiG - - - - - - -
MHPNILHJ_02338 4.23e-103 - - - - - - - -
MHPNILHJ_02339 2.79e-140 - - - - - - - -
MHPNILHJ_02341 9.75e-27 - - - - - - - -
MHPNILHJ_02343 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
MHPNILHJ_02344 7.88e-277 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
MHPNILHJ_02345 2.11e-183 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
MHPNILHJ_02346 9.73e-176 bglS - - M - - - licheninase activity
MHPNILHJ_02347 1.57e-281 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
MHPNILHJ_02348 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
MHPNILHJ_02349 3.04e-221 - - - L - - - DNA synthesis involved in DNA repair
MHPNILHJ_02350 3.23e-60 yxiS - - - - - - -
MHPNILHJ_02351 1.64e-113 - - - T - - - Domain of unknown function (DUF4163)
MHPNILHJ_02352 2.49e-262 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MHPNILHJ_02353 2.83e-185 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
MHPNILHJ_02354 8.25e-271 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
MHPNILHJ_02355 3.81e-105 yxjI - - S - - - LURP-one-related
MHPNILHJ_02358 5.24e-297 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
MHPNILHJ_02359 7.02e-245 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
MHPNILHJ_02360 6.7e-114 yxkC - - S - - - Domain of unknown function (DUF4352)
MHPNILHJ_02362 4.82e-190 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
MHPNILHJ_02363 1.49e-198 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
MHPNILHJ_02364 3.56e-259 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MHPNILHJ_02365 2.39e-191 yxkH - - G - - - Polysaccharide deacetylase
MHPNILHJ_02366 1.02e-283 cimH - - C - - - COG3493 Na citrate symporter
MHPNILHJ_02367 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
MHPNILHJ_02368 5.08e-238 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
MHPNILHJ_02369 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
MHPNILHJ_02370 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
MHPNILHJ_02371 3.54e-191 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MHPNILHJ_02372 8.74e-315 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
MHPNILHJ_02373 2.33e-238 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
MHPNILHJ_02374 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
MHPNILHJ_02375 3.3e-261 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
MHPNILHJ_02376 1.05e-227 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
MHPNILHJ_02377 7.52e-206 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
MHPNILHJ_02378 0.0 ydhP 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MHPNILHJ_02379 1.84e-298 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHPNILHJ_02380 1.26e-62 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MHPNILHJ_02381 3.25e-64 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MHPNILHJ_02382 1.16e-286 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MHPNILHJ_02383 1.06e-66 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
MHPNILHJ_02384 8.85e-212 cbrA3 - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
MHPNILHJ_02385 9.33e-229 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHPNILHJ_02386 7.43e-217 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHPNILHJ_02387 4.07e-139 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
MHPNILHJ_02388 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
MHPNILHJ_02389 3.67e-65 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
MHPNILHJ_02390 1.19e-312 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHPNILHJ_02391 1.89e-64 licA 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MHPNILHJ_02392 4.7e-316 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MHPNILHJ_02393 1.29e-259 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
MHPNILHJ_02394 3.02e-244 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MHPNILHJ_02395 1.96e-49 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHPNILHJ_02396 2.45e-289 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
MHPNILHJ_02397 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHPNILHJ_02398 3.51e-18 - - - S - - - D-Ala-teichoic acid biosynthesis protein
MHPNILHJ_02399 7.25e-213 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
MHPNILHJ_02400 2.16e-150 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
MHPNILHJ_02402 2.87e-205 gspA - - M - - - General stress
MHPNILHJ_02403 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MHPNILHJ_02404 8.3e-309 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHPNILHJ_02405 1.24e-86 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
MHPNILHJ_02406 4.69e-281 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
MHPNILHJ_02407 1.97e-200 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
MHPNILHJ_02408 2.16e-164 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
MHPNILHJ_02409 1.52e-36 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
MHPNILHJ_02410 6.2e-142 ywbG - - M - - - effector of murein hydrolase
MHPNILHJ_02411 9.02e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
MHPNILHJ_02412 2.29e-200 ywbI - - K - - - Transcriptional regulator
MHPNILHJ_02413 2.45e-164 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MHPNILHJ_02414 2.72e-139 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MHPNILHJ_02415 2.41e-246 - - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
MHPNILHJ_02416 5.83e-191 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
MHPNILHJ_02417 9.8e-297 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
MHPNILHJ_02418 6.45e-138 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
MHPNILHJ_02419 4.83e-154 - - - S - - - Streptomycin biosynthesis protein StrF
MHPNILHJ_02420 6.64e-162 - - - H - - - Methionine biosynthesis protein MetW
MHPNILHJ_02422 1.72e-125 - - - K - - - Bacterial regulatory proteins, tetR family
MHPNILHJ_02423 7.8e-78 gtcA - - S - - - GtrA-like protein
MHPNILHJ_02424 1.52e-265 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MHPNILHJ_02425 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
MHPNILHJ_02426 5.74e-48 ydaS - - S - - - membrane
MHPNILHJ_02427 3.01e-226 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
MHPNILHJ_02428 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MHPNILHJ_02429 2.84e-143 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
MHPNILHJ_02430 1.08e-80 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
MHPNILHJ_02431 2.54e-51 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
MHPNILHJ_02432 1.68e-87 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
MHPNILHJ_02433 1.84e-262 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
MHPNILHJ_02434 1.1e-176 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
MHPNILHJ_02435 1.36e-39 - - - S - - - PFAM Stress responsive alpha-beta barrel
MHPNILHJ_02436 4.61e-56 - - - S - - - Ketosteroid isomerase-related protein
MHPNILHJ_02437 8.59e-162 ucpA - - IQ - - - Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHPNILHJ_02438 1.26e-150 - - - K - - - WYL domain
MHPNILHJ_02439 1.83e-233 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MHPNILHJ_02440 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MHPNILHJ_02442 1.29e-193 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
MHPNILHJ_02443 9.04e-317 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MHPNILHJ_02444 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
MHPNILHJ_02445 6.09e-27 ywdA - - - - - - -
MHPNILHJ_02446 2.79e-185 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
MHPNILHJ_02448 1.44e-186 ywdF - - S - - - Glycosyltransferase like family 2
MHPNILHJ_02449 2.42e-169 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MHPNILHJ_02450 2.73e-56 ywdI - - S - - - Family of unknown function (DUF5327)
MHPNILHJ_02451 8.52e-288 ywdJ - - F - - - Xanthine uracil
MHPNILHJ_02452 4.39e-76 ywdK - - S - - - small membrane protein
MHPNILHJ_02453 1.29e-83 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
MHPNILHJ_02454 4.13e-180 spsA - - M - - - Spore Coat
MHPNILHJ_02455 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
MHPNILHJ_02456 5.44e-277 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
MHPNILHJ_02457 6.34e-195 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
MHPNILHJ_02458 2.84e-264 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
MHPNILHJ_02459 2.62e-158 spsF - - M ko:K07257 - ko00000 Spore Coat
MHPNILHJ_02460 1.49e-212 spsG - - M - - - Spore Coat
MHPNILHJ_02461 4.12e-170 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MHPNILHJ_02462 4.64e-227 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MHPNILHJ_02463 1.7e-201 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MHPNILHJ_02464 2.6e-109 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
MHPNILHJ_02465 4.02e-80 - - - - - - - -
MHPNILHJ_02466 8.64e-312 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
MHPNILHJ_02467 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
MHPNILHJ_02468 0.0 rocB - - E - - - arginine degradation protein
MHPNILHJ_02469 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
MHPNILHJ_02470 9.06e-238 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
MHPNILHJ_02471 1.14e-276 ywfA - - EGP - - - -transporter
MHPNILHJ_02472 4.49e-143 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
MHPNILHJ_02473 4.67e-174 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
MHPNILHJ_02474 2.21e-178 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHPNILHJ_02475 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
MHPNILHJ_02476 8.14e-265 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
MHPNILHJ_02477 1.6e-290 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
MHPNILHJ_02478 2.12e-179 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
MHPNILHJ_02479 1.9e-184 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
MHPNILHJ_02480 2.27e-222 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
MHPNILHJ_02481 6.26e-205 - - - S - - - Conserved hypothetical protein 698
MHPNILHJ_02482 6.57e-200 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
MHPNILHJ_02483 4.66e-197 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
MHPNILHJ_02485 6.53e-210 - - - - - - - -
MHPNILHJ_02488 1.75e-207 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC transporter (permease)
MHPNILHJ_02489 4.46e-54 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHPNILHJ_02490 1.29e-117 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHPNILHJ_02491 7.2e-109 - - - S - - - membrane
MHPNILHJ_02492 7.34e-66 - - - K ko:K10947 - ko00000,ko03000 PadR family transcriptional regulator
MHPNILHJ_02494 6.18e-139 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
MHPNILHJ_02495 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
MHPNILHJ_02496 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
MHPNILHJ_02497 1.37e-113 ywgA - - - ko:K09388 - ko00000 -
MHPNILHJ_02498 4.79e-307 potE5 - - E ko:K03294 - ko00000 C-terminus of AA_permease
MHPNILHJ_02499 3.29e-90 ywhA - - K - - - Transcriptional regulator
MHPNILHJ_02500 2.37e-34 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
MHPNILHJ_02501 1.1e-152 ywhC - - S - - - Peptidase family M50
MHPNILHJ_02502 2.07e-116 ywhD - - S - - - YwhD family
MHPNILHJ_02503 1.96e-93 - - - - - - - -
MHPNILHJ_02504 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
MHPNILHJ_02505 6.45e-203 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MHPNILHJ_02506 2.87e-213 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
MHPNILHJ_02508 3.16e-102 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
MHPNILHJ_02509 1.55e-248 ywhL - - CO - - - amine dehydrogenase activity
MHPNILHJ_02511 4.46e-94 ywiB - - S - - - protein conserved in bacteria
MHPNILHJ_02512 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
MHPNILHJ_02513 7.56e-267 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
MHPNILHJ_02514 5.83e-162 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
MHPNILHJ_02515 8.59e-162 ywiC - - S - - - YwiC-like protein
MHPNILHJ_02516 8.63e-102 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
MHPNILHJ_02517 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MHPNILHJ_02518 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
MHPNILHJ_02519 1.07e-110 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
MHPNILHJ_02520 1.61e-149 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
MHPNILHJ_02521 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MHPNILHJ_02522 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
MHPNILHJ_02523 3.23e-58 ywjC - - - - - - -
MHPNILHJ_02524 5.39e-224 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
MHPNILHJ_02525 1.51e-263 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
MHPNILHJ_02526 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
MHPNILHJ_02527 1.53e-71 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MHPNILHJ_02528 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MHPNILHJ_02529 1.84e-117 ywjG - - S - - - Domain of unknown function (DUF2529)
MHPNILHJ_02530 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
MHPNILHJ_02531 4.53e-203 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
MHPNILHJ_02532 3.69e-143 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MHPNILHJ_02533 1.59e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MHPNILHJ_02534 9.65e-223 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
MHPNILHJ_02535 5.13e-304 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MHPNILHJ_02536 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
MHPNILHJ_02537 6.49e-131 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
MHPNILHJ_02538 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
MHPNILHJ_02539 6.87e-194 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
MHPNILHJ_02540 2.52e-115 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
MHPNILHJ_02541 2.93e-85 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MHPNILHJ_02542 2.06e-240 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MHPNILHJ_02543 3.54e-196 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MHPNILHJ_02545 4.04e-77 ywlA - - S - - - Uncharacterised protein family (UPF0715)
MHPNILHJ_02546 1.73e-148 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
MHPNILHJ_02547 6.75e-96 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
MHPNILHJ_02548 1.34e-237 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MHPNILHJ_02549 1.86e-116 mntP - - P - - - Probably functions as a manganese efflux pump
MHPNILHJ_02550 1.84e-95 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MHPNILHJ_02551 9.2e-104 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
MHPNILHJ_02552 3.53e-123 ywlG - - S - - - Belongs to the UPF0340 family
MHPNILHJ_02553 5.69e-299 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MHPNILHJ_02554 1.3e-146 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MHPNILHJ_02555 4.49e-80 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
MHPNILHJ_02556 5.19e-168 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
MHPNILHJ_02557 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MHPNILHJ_02558 3.35e-82 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MHPNILHJ_02559 1.95e-116 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MHPNILHJ_02560 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MHPNILHJ_02561 1.1e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MHPNILHJ_02562 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MHPNILHJ_02563 3.36e-82 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
MHPNILHJ_02564 1.98e-115 ywmA - - - - - - -
MHPNILHJ_02565 1.85e-44 ywzB - - S - - - membrane
MHPNILHJ_02566 1.27e-169 ywmB - - S - - - TATA-box binding
MHPNILHJ_02567 1.85e-301 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MHPNILHJ_02568 6.86e-232 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
MHPNILHJ_02569 4.74e-145 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
MHPNILHJ_02570 2.79e-154 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
MHPNILHJ_02572 2.91e-183 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MHPNILHJ_02573 2.09e-243 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MHPNILHJ_02574 1.44e-114 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
MHPNILHJ_02575 1.01e-105 ywmF - - S - - - Peptidase M50
MHPNILHJ_02576 2.41e-16 csbD - - K - - - CsbD-like
MHPNILHJ_02577 1.94e-66 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
MHPNILHJ_02578 4.37e-81 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
MHPNILHJ_02579 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
MHPNILHJ_02580 3.09e-88 ywnA - - K - - - Transcriptional regulator
MHPNILHJ_02581 3.75e-116 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
MHPNILHJ_02582 1.33e-77 ywnC - - S - - - Family of unknown function (DUF5362)
MHPNILHJ_02583 1.12e-21 yqgA - - - - - - -
MHPNILHJ_02584 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MHPNILHJ_02585 2.45e-88 ywnF - - S - - - Family of unknown function (DUF5392)
MHPNILHJ_02587 7.6e-113 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
MHPNILHJ_02588 1.17e-175 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
MHPNILHJ_02589 3.41e-88 ywnJ - - S - - - VanZ like family
MHPNILHJ_02590 5.56e-130 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
MHPNILHJ_02591 1.11e-262 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
MHPNILHJ_02592 1.51e-75 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
MHPNILHJ_02593 3.63e-289 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
MHPNILHJ_02594 2.1e-128 yjgF - - Q - - - Isochorismatase family
MHPNILHJ_02595 2.05e-147 ywoD - - EGP - - - Major facilitator superfamily
MHPNILHJ_02596 6.07e-141 ywoD - - EGP - - - Major facilitator superfamily
MHPNILHJ_02597 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
MHPNILHJ_02598 3.92e-270 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
MHPNILHJ_02599 5.3e-93 ywoH - - K - - - transcriptional
MHPNILHJ_02600 5.93e-60 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
MHPNILHJ_02601 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
MHPNILHJ_02602 1.16e-170 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
MHPNILHJ_02603 5.1e-176 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
MHPNILHJ_02604 4.41e-247 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
MHPNILHJ_02605 3.15e-98 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MHPNILHJ_02606 2.54e-72 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MHPNILHJ_02607 1.79e-89 ywpF - - S - - - YwpF-like protein
MHPNILHJ_02608 1.83e-74 ywpG - - - - - - -
MHPNILHJ_02609 4.94e-75 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
MHPNILHJ_02610 5.39e-178 glcR - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
MHPNILHJ_02611 7.72e-195 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
MHPNILHJ_02612 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
MHPNILHJ_02613 0.0 ywqB - - S - - - SWIM zinc finger
MHPNILHJ_02614 3e-22 - - - - - - - -
MHPNILHJ_02615 1.2e-143 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
MHPNILHJ_02616 3.37e-152 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
MHPNILHJ_02617 6.3e-174 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
MHPNILHJ_02618 2.45e-304 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MHPNILHJ_02619 1.68e-182 ywqG - - S - - - Domain of unknown function (DUF1963)
MHPNILHJ_02621 1.59e-47 ywqI - - S - - - Family of unknown function (DUF5344)
MHPNILHJ_02622 8.84e-288 ywqJ - - S - - - Pre-toxin TG
MHPNILHJ_02623 2.19e-75 - - - S - - - SUKH-4 immunity protein
MHPNILHJ_02624 1.92e-25 - - - - - - - -
MHPNILHJ_02625 3.77e-97 - - - S ko:K21494 - ko00000,ko02048 SMI1 / KNR4 family
MHPNILHJ_02626 7.15e-83 - - - - - - - -
MHPNILHJ_02627 1.29e-130 - - - - - - - -
MHPNILHJ_02628 2.03e-112 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
MHPNILHJ_02629 7.48e-126 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
MHPNILHJ_02630 3.97e-107 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
MHPNILHJ_02631 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
MHPNILHJ_02633 3.45e-143 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MHPNILHJ_02634 6.86e-13 - - - - - - - -
MHPNILHJ_02635 9.11e-261 cotH - - M ko:K06330 - ko00000 Spore Coat
MHPNILHJ_02636 4.38e-157 cotB - - - ko:K06325 - ko00000 -
MHPNILHJ_02637 8.96e-150 ywrJ - - - - - - -
MHPNILHJ_02638 5.9e-297 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MHPNILHJ_02639 6.98e-211 alsR - - K - - - LysR substrate binding domain
MHPNILHJ_02640 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
MHPNILHJ_02641 1.51e-186 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
MHPNILHJ_02642 2.88e-113 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
MHPNILHJ_02643 5.4e-112 batE - - T - - - Sh3 type 3 domain protein
MHPNILHJ_02644 7.75e-205 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
MHPNILHJ_02645 1.21e-201 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MHPNILHJ_02646 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
MHPNILHJ_02647 1.04e-80 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MHPNILHJ_02648 1.74e-195 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MHPNILHJ_02649 4.38e-221 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
MHPNILHJ_02650 9.16e-247 gerKC - - S - - - Spore germination B3/ GerAC like, C-terminal
MHPNILHJ_02651 6.95e-228 - - - E - - - Spore germination protein
MHPNILHJ_02652 1.22e-253 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
MHPNILHJ_02653 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
MHPNILHJ_02654 2.95e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
MHPNILHJ_02655 7.41e-276 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
MHPNILHJ_02656 1.16e-28 ywtC - - - - - - -
MHPNILHJ_02657 6.5e-287 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MHPNILHJ_02658 9.05e-59 yttA - - S - - - Pfam Transposase IS66
MHPNILHJ_02659 1.33e-195 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
MHPNILHJ_02660 2.02e-223 ywtF_2 - - K - - - Transcriptional regulator
MHPNILHJ_02661 9.98e-304 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MHPNILHJ_02662 0.0 - - - J ko:K07011 - ko00000 Glycosyl transferase family 2
MHPNILHJ_02663 3.1e-218 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
MHPNILHJ_02664 2.94e-243 gerBB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
MHPNILHJ_02665 0.0 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
MHPNILHJ_02666 9.82e-234 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
MHPNILHJ_02667 2.3e-290 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MHPNILHJ_02668 5.65e-258 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MHPNILHJ_02669 6.85e-179 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MHPNILHJ_02670 2.69e-91 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
MHPNILHJ_02671 0.0 tagE 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferase 1 domain A
MHPNILHJ_02672 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MHPNILHJ_02673 7.77e-174 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
MHPNILHJ_02674 1.55e-241 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MHPNILHJ_02675 2.14e-200 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
MHPNILHJ_02676 4.2e-235 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MHPNILHJ_02677 1.15e-179 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
MHPNILHJ_02678 1.99e-39 - - - - - - - -
MHPNILHJ_02679 0.0 lytB - - D - - - Stage II sporulation protein
MHPNILHJ_02680 5.41e-269 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
MHPNILHJ_02681 8.51e-151 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MHPNILHJ_02682 0.0 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MHPNILHJ_02683 2.76e-270 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
MHPNILHJ_02684 5.86e-310 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MHPNILHJ_02685 8.4e-317 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
MHPNILHJ_02686 8.08e-138 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
MHPNILHJ_02687 2.22e-182 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
MHPNILHJ_02688 1.85e-284 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
MHPNILHJ_02689 8.94e-233 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
MHPNILHJ_02690 9.24e-234 yvhJ - - K - - - Transcriptional regulator
MHPNILHJ_02691 1.1e-150 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
MHPNILHJ_02692 2.31e-245 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
MHPNILHJ_02693 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MHPNILHJ_02694 3.16e-197 degV - - S - - - protein conserved in bacteria
MHPNILHJ_02695 5.41e-316 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MHPNILHJ_02696 2.93e-56 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
MHPNILHJ_02697 4.91e-79 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
MHPNILHJ_02698 6.15e-95 yvyF - - S - - - flagellar protein
MHPNILHJ_02699 5.05e-52 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
MHPNILHJ_02700 1.43e-101 yvyG - - NOU - - - FlgN protein
MHPNILHJ_02701 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
MHPNILHJ_02702 1.63e-206 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
MHPNILHJ_02703 1.27e-104 yviE - - - - - - -
MHPNILHJ_02704 5.2e-98 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
MHPNILHJ_02705 2.67e-43 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
MHPNILHJ_02706 9.98e-154 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MHPNILHJ_02707 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MHPNILHJ_02708 2.18e-83 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
MHPNILHJ_02709 1.57e-09 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
MHPNILHJ_02710 1.92e-89 - - - - - - - -
MHPNILHJ_02711 4.25e-130 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MHPNILHJ_02712 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MHPNILHJ_02713 1.08e-222 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MHPNILHJ_02714 5.39e-189 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
MHPNILHJ_02715 1.47e-58 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
MHPNILHJ_02716 3.53e-158 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
MHPNILHJ_02717 1.48e-196 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
MHPNILHJ_02718 5.2e-276 ywoF - - P - - - Right handed beta helix region
MHPNILHJ_02719 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
MHPNILHJ_02720 5.83e-72 swrA - - S - - - Swarming motility protein
MHPNILHJ_02721 7.71e-276 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MHPNILHJ_02724 3.49e-290 yvkA - - P - - - -transporter
MHPNILHJ_02725 1.12e-119 yvkB - - K - - - Transcriptional regulator
MHPNILHJ_02726 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
MHPNILHJ_02727 2.59e-45 csbA - - S - - - protein conserved in bacteria
MHPNILHJ_02728 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MHPNILHJ_02729 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MHPNILHJ_02730 1.29e-40 yvkN - - - - - - -
MHPNILHJ_02731 5.13e-61 yvlA - - - - - - -
MHPNILHJ_02732 4.14e-214 yvlB - - S - - - Putative adhesin
MHPNILHJ_02733 8.1e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
MHPNILHJ_02734 1.09e-65 yvlD - - S ko:K08972 - ko00000 Membrane
MHPNILHJ_02735 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
MHPNILHJ_02736 6.76e-131 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
MHPNILHJ_02737 2.9e-169 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
MHPNILHJ_02738 1.44e-168 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MHPNILHJ_02739 2.47e-272 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
MHPNILHJ_02740 6e-216 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MHPNILHJ_02741 5.06e-193 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MHPNILHJ_02742 3.18e-155 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
MHPNILHJ_02743 1.2e-110 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
MHPNILHJ_02744 3.83e-173 yvpB - - NU - - - protein conserved in bacteria
MHPNILHJ_02745 8.64e-258 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MHPNILHJ_02746 1.45e-145 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MHPNILHJ_02747 4.77e-279 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MHPNILHJ_02748 6.49e-135 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
MHPNILHJ_02749 1.75e-141 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MHPNILHJ_02750 6.02e-163 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MHPNILHJ_02751 4.63e-175 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MHPNILHJ_02752 8.74e-139 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
MHPNILHJ_02753 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
MHPNILHJ_02754 1.49e-153 mprA3 - - T - - - COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHPNILHJ_02755 1.01e-231 sasA - - T - - - Histidine kinase
MHPNILHJ_02756 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
MHPNILHJ_02757 1.39e-194 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
MHPNILHJ_02758 4.78e-223 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MHPNILHJ_02759 2.98e-112 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
MHPNILHJ_02760 1.41e-211 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
MHPNILHJ_02761 3.51e-223 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
MHPNILHJ_02762 5.16e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
MHPNILHJ_02763 6.52e-49 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
MHPNILHJ_02764 1.94e-165 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
MHPNILHJ_02765 4.11e-100 - - - M - - - Ribonuclease
MHPNILHJ_02766 7.72e-229 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MHPNILHJ_02767 8.55e-135 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
MHPNILHJ_02768 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
MHPNILHJ_02769 5.98e-66 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
MHPNILHJ_02770 2.87e-132 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
MHPNILHJ_02771 1.06e-110 - - - - - - - -
MHPNILHJ_02772 6.64e-313 - - - EGP - - - Sugar (and other) transporter
MHPNILHJ_02773 3.16e-258 yraM - - S - - - PrpF protein
MHPNILHJ_02774 1.4e-202 yraN - - K - - - Transcriptional regulator
MHPNILHJ_02775 3.74e-136 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MHPNILHJ_02776 9.34e-227 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
MHPNILHJ_02777 5.05e-279 rafB - - P ko:K02532 - ko00000,ko02000 LacY proton/sugar symporter
MHPNILHJ_02778 0.0 cscA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
MHPNILHJ_02780 3.08e-44 - - - - - - - -
MHPNILHJ_02781 0.0 - - - I - - - Pfam Lipase (class 3)
MHPNILHJ_02782 6.57e-25 - - - S - - - Protein of unknown function (DUF1433)
MHPNILHJ_02783 1.63e-30 - - - S - - - Protein of unknown function (DUF1433)
MHPNILHJ_02784 3.4e-43 - - - S - - - Protein of unknown function (DUF1433)
MHPNILHJ_02785 1.25e-63 - - - S - - - Protein of unknown function (DUF3237)
MHPNILHJ_02786 7.09e-121 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
MHPNILHJ_02787 3.65e-108 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MHPNILHJ_02788 5.22e-137 yyaS - - S ko:K07149 - ko00000 Membrane
MHPNILHJ_02789 2.74e-98 glx2 - - S - - - Metallo-beta-lactamase superfamily
MHPNILHJ_02790 4.2e-164 - - - CH - - - FAD binding domain
MHPNILHJ_02791 8.3e-111 ywjB - - H - - - RibD C-terminal domain
MHPNILHJ_02793 8.66e-312 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
MHPNILHJ_02794 5.95e-101 - - - K ko:K19417 - ko00000,ko03000 transcriptional
MHPNILHJ_02795 4.37e-151 epsA - - M ko:K19420 - ko00000 biosynthesis protein
MHPNILHJ_02796 3.12e-151 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
MHPNILHJ_02797 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
MHPNILHJ_02798 4.24e-269 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
MHPNILHJ_02799 3.44e-200 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
MHPNILHJ_02800 1.95e-253 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
MHPNILHJ_02801 6.38e-258 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
MHPNILHJ_02802 6.01e-245 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
MHPNILHJ_02803 6.55e-251 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
MHPNILHJ_02804 1.71e-239 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
MHPNILHJ_02805 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MHPNILHJ_02806 2.7e-131 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MHPNILHJ_02807 1.28e-70 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
MHPNILHJ_02808 2.79e-275 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
MHPNILHJ_02809 2.77e-224 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
MHPNILHJ_02810 4.01e-44 yvfG - - S - - - YvfG protein
MHPNILHJ_02811 1.61e-293 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
MHPNILHJ_02812 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
MHPNILHJ_02813 1.16e-151 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
MHPNILHJ_02814 4.18e-264 - - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MHPNILHJ_02815 1.69e-170 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MHPNILHJ_02816 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
MHPNILHJ_02817 3.12e-167 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MHPNILHJ_02818 3.08e-287 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
MHPNILHJ_02819 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
MHPNILHJ_02820 2.88e-190 gntR - - K - - - RpiR family transcriptional regulator
MHPNILHJ_02822 6.69e-275 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
MHPNILHJ_02823 5.35e-196 yvbV - - EG - - - EamA-like transporter family
MHPNILHJ_02824 5.29e-161 yvbU - - K - - - Transcriptional regulator
MHPNILHJ_02825 1.78e-241 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MHPNILHJ_02826 6.86e-255 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
MHPNILHJ_02827 0.0 araE - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MHPNILHJ_02829 1.91e-236 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MHPNILHJ_02830 2.83e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MHPNILHJ_02831 1.55e-274 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
MHPNILHJ_02832 1.49e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MHPNILHJ_02833 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
MHPNILHJ_02834 9.69e-310 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MHPNILHJ_02835 2.83e-286 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
MHPNILHJ_02836 9.36e-317 - 1.1.1.136 - M ko:K13015 ko00520,map00520 ko00000,ko00001,ko01000,ko01005 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MHPNILHJ_02837 2.68e-275 - 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
MHPNILHJ_02838 6.48e-215 arnA 4.2.1.46, 5.1.3.2 - M ko:K01710,ko:K01784 ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130 ko00000,ko00001,ko00002,ko01000 GDP-mannose 4,6 dehydratase
MHPNILHJ_02839 6.62e-279 - - - E - - - UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MHPNILHJ_02840 2.49e-179 - - - M - - - Protein involved in cellulose biosynthesis
MHPNILHJ_02841 1.13e-182 - - - C - - - WbqC-like protein family
MHPNILHJ_02842 3.54e-159 - - - S - - - GlcNAc-PI de-N-acetylase
MHPNILHJ_02843 5.36e-219 - - - - - - - -
MHPNILHJ_02844 4.16e-260 - - - EGP - - - Major facilitator Superfamily
MHPNILHJ_02845 5.07e-103 yvbK - - K - - - acetyltransferase
MHPNILHJ_02846 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
MHPNILHJ_02847 1.58e-149 yvbI - - M - - - Membrane
MHPNILHJ_02848 1.55e-134 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
MHPNILHJ_02849 2.67e-125 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
MHPNILHJ_02850 1.21e-268 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MHPNILHJ_02851 5.4e-143 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
MHPNILHJ_02852 6.03e-218 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MHPNILHJ_02853 2.95e-139 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
MHPNILHJ_02854 3.5e-108 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
MHPNILHJ_02855 1.25e-262 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MHPNILHJ_02856 2.57e-141 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
MHPNILHJ_02857 4.75e-215 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MHPNILHJ_02858 3.47e-143 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
MHPNILHJ_02859 2.46e-158 spaF - - V ko:K01990,ko:K20459,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MHPNILHJ_02860 3.17e-153 spaE - - S ko:K20491 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
MHPNILHJ_02861 3.2e-166 spaG - - S ko:K20492 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
MHPNILHJ_02862 5.04e-154 spaR - - K ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
MHPNILHJ_02863 1.49e-309 spaK 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
MHPNILHJ_02864 1.17e-67 yvaP - - K - - - transcriptional
MHPNILHJ_02865 1.09e-90 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
MHPNILHJ_02866 1.07e-89 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
MHPNILHJ_02867 1.64e-47 yvzC - - K - - - transcriptional
MHPNILHJ_02868 9.24e-36 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
MHPNILHJ_02869 6.92e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
MHPNILHJ_02870 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MHPNILHJ_02871 4.85e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MHPNILHJ_02873 9.41e-56 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
MHPNILHJ_02874 3.93e-178 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
MHPNILHJ_02875 3.97e-204 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
MHPNILHJ_02876 2.71e-129 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
MHPNILHJ_02877 1.81e-164 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
MHPNILHJ_02878 5.62e-185 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
MHPNILHJ_02879 9.1e-151 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MHPNILHJ_02880 6.21e-151 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MHPNILHJ_02881 2.03e-177 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
MHPNILHJ_02882 1.65e-221 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MHPNILHJ_02883 9.38e-58 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
MHPNILHJ_02884 2.7e-313 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MHPNILHJ_02885 1.03e-153 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MHPNILHJ_02886 3.08e-243 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
MHPNILHJ_02887 2.05e-61 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
MHPNILHJ_02888 1.09e-38 - - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Heavy-metal-associated domain
MHPNILHJ_02889 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
MHPNILHJ_02890 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
MHPNILHJ_02891 4.84e-133 bdbD - - O - - - Thioredoxin
MHPNILHJ_02892 2.51e-94 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
MHPNILHJ_02893 8.69e-187 - - - S - - - Metallo-peptidase family M12
MHPNILHJ_02894 9.04e-130 yvgT - - S - - - membrane
MHPNILHJ_02895 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
MHPNILHJ_02896 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MHPNILHJ_02897 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
MHPNILHJ_02898 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
MHPNILHJ_02899 6.3e-110 yvgO - - - - - - -
MHPNILHJ_02900 1.2e-198 yvgN - - S - - - reductase
MHPNILHJ_02901 1.44e-229 sagI - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
MHPNILHJ_02902 3.65e-235 sagH - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
MHPNILHJ_02903 1.12e-216 sagG - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
MHPNILHJ_02904 3.01e-237 - - - T - - - Histidine kinase
MHPNILHJ_02905 2.17e-146 yfiK - - K - - - Regulator
MHPNILHJ_02906 1.21e-128 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
MHPNILHJ_02907 4.92e-174 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
MHPNILHJ_02908 8.02e-204 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
MHPNILHJ_02909 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
MHPNILHJ_02910 2.04e-110 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
MHPNILHJ_02911 4.34e-19 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
MHPNILHJ_02912 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
MHPNILHJ_02913 2.17e-153 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MHPNILHJ_02914 2.12e-226 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MHPNILHJ_02915 6.08e-234 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHPNILHJ_02916 9.44e-217 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHPNILHJ_02917 6.61e-187 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MHPNILHJ_02918 1.38e-70 yvrL - - S - - - Regulatory protein YrvL
MHPNILHJ_02919 9.98e-292 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
MHPNILHJ_02920 1.88e-21 - - - S - - - YvrJ protein family
MHPNILHJ_02921 1.47e-130 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
MHPNILHJ_02922 1.14e-48 - - - - - - - -
MHPNILHJ_02923 4.48e-171 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHPNILHJ_02924 0.0 yvrG - - T - - - Histidine kinase
MHPNILHJ_02925 2.36e-213 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
MHPNILHJ_02926 4.79e-178 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MHPNILHJ_02927 1.07e-211 yvrC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MHPNILHJ_02928 5.73e-224 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHPNILHJ_02929 1.87e-257 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
MHPNILHJ_02930 3.89e-125 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
MHPNILHJ_02931 9.45e-281 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
MHPNILHJ_02932 7.39e-65 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
MHPNILHJ_02933 6e-128 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
MHPNILHJ_02934 1.33e-165 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
MHPNILHJ_02935 6.74e-159 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
MHPNILHJ_02936 2.86e-246 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MHPNILHJ_02937 8.35e-139 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MHPNILHJ_02938 9.22e-248 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
MHPNILHJ_02939 5.79e-233 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
MHPNILHJ_02940 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
MHPNILHJ_02941 1.83e-33 - - - S - - - Protein of unknown function (DUF3970)
MHPNILHJ_02942 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MHPNILHJ_02943 6.7e-196 yuxN - - K - - - Transcriptional regulator
MHPNILHJ_02944 2.68e-32 - - - - - - - -
MHPNILHJ_02945 9.22e-317 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MHPNILHJ_02946 2.06e-160 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHPNILHJ_02947 8.65e-295 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MHPNILHJ_02948 5.63e-101 dps2 - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
MHPNILHJ_02949 1.77e-177 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MHPNILHJ_02950 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
MHPNILHJ_02951 2.79e-62 - - - S - - - YusW-like protein
MHPNILHJ_02952 1.06e-191 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MHPNILHJ_02953 1.46e-50 yusU - - S - - - Protein of unknown function (DUF2573)
MHPNILHJ_02954 3.73e-159 - 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
MHPNILHJ_02955 1.48e-23 - - - K - - - Helix-turn-helix XRE-family like proteins
MHPNILHJ_02956 6.56e-74 - - - L - - - PFAM Restriction endonuclease BamHI
MHPNILHJ_02957 0.0 yusP - - P - - - Major facilitator superfamily
MHPNILHJ_02958 1.47e-86 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
MHPNILHJ_02959 3.53e-69 yusN - - M - - - Coat F domain
MHPNILHJ_02960 7.03e-53 - - - - - - - -
MHPNILHJ_02961 6.69e-209 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
MHPNILHJ_02962 1.72e-10 - - - S - - - YuzL-like protein
MHPNILHJ_02963 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
MHPNILHJ_02964 3.02e-275 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
MHPNILHJ_02965 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
MHPNILHJ_02966 4.13e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
MHPNILHJ_02967 1.19e-84 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
MHPNILHJ_02968 2.99e-53 yusG - - S - - - Protein of unknown function (DUF2553)
MHPNILHJ_02969 6.99e-79 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
MHPNILHJ_02970 2.25e-70 yusE - - CO - - - Thioredoxin
MHPNILHJ_02971 5.08e-74 yusD - - S - - - SCP-2 sterol transfer family
MHPNILHJ_02972 1.51e-236 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MHPNILHJ_02973 3.3e-135 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
MHPNILHJ_02974 2.88e-183 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
MHPNILHJ_02975 2.97e-83 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MHPNILHJ_02977 3.82e-183 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
MHPNILHJ_02978 1.75e-311 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
MHPNILHJ_02979 3.01e-294 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MHPNILHJ_02980 8.89e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
MHPNILHJ_02981 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
MHPNILHJ_02982 2.49e-192 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
MHPNILHJ_02983 7.45e-94 yncE - - S - - - Protein of unknown function (DUF2691)
MHPNILHJ_02984 1.09e-128 - - - Q - - - ubiE/COQ5 methyltransferase family
MHPNILHJ_02985 2.19e-251 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
MHPNILHJ_02986 1.36e-84 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
MHPNILHJ_02988 2.77e-27 - - - S - - - Sporulation delaying protein SdpA
MHPNILHJ_02989 1.66e-96 - - - - - - - -
MHPNILHJ_02991 8.02e-204 - - - K - - - helix_turn_helix, mercury resistance
MHPNILHJ_02992 8.37e-232 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
MHPNILHJ_02993 1.08e-305 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
MHPNILHJ_02994 1.24e-201 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MHPNILHJ_02995 2.91e-199 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
MHPNILHJ_02996 1.71e-202 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
MHPNILHJ_02997 1.14e-170 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
MHPNILHJ_02998 1.49e-252 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MHPNILHJ_02999 3.19e-207 bsn - - L - - - Ribonuclease
MHPNILHJ_03000 7.27e-285 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
MHPNILHJ_03001 2.55e-287 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
MHPNILHJ_03002 8.83e-267 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
MHPNILHJ_03003 6.3e-86 - - - - - - - -
MHPNILHJ_03004 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
MHPNILHJ_03005 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
MHPNILHJ_03006 2.23e-73 - - - S - - - phosphoglycolate phosphatase activity
MHPNILHJ_03007 7.05e-215 yunF - - S - - - Protein of unknown function DUF72
MHPNILHJ_03008 5.58e-182 yunE - - S ko:K07090 - ko00000 membrane transporter protein
MHPNILHJ_03009 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MHPNILHJ_03010 1.53e-164 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
MHPNILHJ_03011 1.26e-245 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
MHPNILHJ_03012 3.92e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MHPNILHJ_03013 3.71e-62 yutD - - S - - - protein conserved in bacteria
MHPNILHJ_03014 3e-93 yutE - - S - - - Protein of unknown function DUF86
MHPNILHJ_03015 1.18e-179 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MHPNILHJ_03016 1.07e-108 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
MHPNILHJ_03017 5.56e-244 yutH - - S - - - Spore coat protein
MHPNILHJ_03018 1.37e-306 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
MHPNILHJ_03019 3.65e-248 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MHPNILHJ_03020 2.22e-206 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MHPNILHJ_03021 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
MHPNILHJ_03022 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
MHPNILHJ_03023 3.17e-71 yuzD - - S - - - protein conserved in bacteria
MHPNILHJ_03024 2.72e-262 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
MHPNILHJ_03025 4.81e-50 yuzB - - S - - - Belongs to the UPF0349 family
MHPNILHJ_03026 2.11e-271 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MHPNILHJ_03027 3.59e-204 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MHPNILHJ_03028 1.88e-80 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
MHPNILHJ_03029 5.47e-166 - - - L - - - Belongs to the 'phage' integrase family
MHPNILHJ_03030 2.48e-129 - - - S - - - Helix-turn-helix domain
MHPNILHJ_03032 9.37e-06 - - - K - - - Cro/C1-type HTH DNA-binding domain
MHPNILHJ_03034 4.24e-10 - - - - - - - -
MHPNILHJ_03046 5.88e-45 - - - - - - - -
MHPNILHJ_03048 1.03e-16 - - - - - - - -
MHPNILHJ_03049 1.57e-09 - - - - - - - -
MHPNILHJ_03052 3.91e-87 - - - L - - - Phage integrase family
MHPNILHJ_03053 0.0 - - - S - - - TIGRFAM Phage
MHPNILHJ_03054 2.32e-37 - - - S - - - Helix-turn-helix of insertion element transposase
MHPNILHJ_03055 1.17e-200 - - - - - - - -
MHPNILHJ_03056 2.52e-102 - - - S - - - Phage minor capsid protein 2
MHPNILHJ_03057 2.02e-05 - - - - - - - -
MHPNILHJ_03058 2.82e-101 - - - - - - - -
MHPNILHJ_03060 2.62e-34 - - - - - - - -
MHPNILHJ_03063 7.2e-25 - - - - - - - -
MHPNILHJ_03064 1.33e-60 - - - N - - - domain, Protein
MHPNILHJ_03065 2.1e-31 - - - - - - - -
MHPNILHJ_03067 1.25e-50 - - - D - - - phage tail tape measure protein
MHPNILHJ_03068 1.09e-151 - - - D - - - phage tail tape measure protein
MHPNILHJ_03069 1.45e-67 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
MHPNILHJ_03070 3.65e-93 - - - L - - - Prophage endopeptidase tail
MHPNILHJ_03071 0.0 - - - S - - - Peptidase_G2, IMC autoproteolytic cleavage domain
MHPNILHJ_03072 2.39e-109 - - - - - - - -
MHPNILHJ_03075 1.66e-39 - - - S - - - BhlA holin family
MHPNILHJ_03076 1.42e-185 - 3.5.1.28 - MT ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
MHPNILHJ_03077 7.35e-46 - - - S - - - Bacteriophage A118-like holin, Hol118
MHPNILHJ_03079 5.14e-168 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
MHPNILHJ_03080 5.08e-55 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
MHPNILHJ_03082 5.3e-44 - - - S - - - Bacteriocin class IId cyclical uberolysin-like
MHPNILHJ_03084 1.41e-151 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MHPNILHJ_03085 1.09e-86 - - - CP - - - Membrane
MHPNILHJ_03086 1.57e-37 - - - - - - - -
MHPNILHJ_03087 1.29e-234 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MHPNILHJ_03089 1.15e-235 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
MHPNILHJ_03090 3.83e-297 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
MHPNILHJ_03091 1.21e-45 yuiB - - S - - - Putative membrane protein
MHPNILHJ_03092 2.23e-149 yuiC - - S - - - protein conserved in bacteria
MHPNILHJ_03093 1.37e-98 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
MHPNILHJ_03094 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MHPNILHJ_03095 9.11e-273 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
MHPNILHJ_03096 4.35e-130 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
MHPNILHJ_03097 2.02e-149 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
MHPNILHJ_03098 1.49e-194 eSD - - S ko:K07017 - ko00000 Putative esterase
MHPNILHJ_03099 5.34e-166 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
MHPNILHJ_03100 1.74e-273 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
MHPNILHJ_03101 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
MHPNILHJ_03102 1.4e-208 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
MHPNILHJ_03103 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHPNILHJ_03104 3.6e-42 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
MHPNILHJ_03105 1.24e-161 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
MHPNILHJ_03106 7.76e-259 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
MHPNILHJ_03107 4.08e-289 yukF - - QT - - - Transcriptional regulator
MHPNILHJ_03108 1.94e-60 yukE - - S - - - Belongs to the WXG100 family
MHPNILHJ_03109 5.28e-53 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
MHPNILHJ_03110 8.65e-255 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
MHPNILHJ_03111 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MHPNILHJ_03112 0.0 yueB - - S - - - type VII secretion protein EsaA
MHPNILHJ_03113 4.27e-97 yueC - - S - - - Family of unknown function (DUF5383)
MHPNILHJ_03114 2.35e-159 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHPNILHJ_03115 1.83e-123 yueE - - S ko:K06950 - ko00000 phosphohydrolase
MHPNILHJ_03116 1.98e-31 - - - S - - - Protein of unknown function (DUF2642)
MHPNILHJ_03117 1.15e-232 yueF - - S - - - transporter activity
MHPNILHJ_03118 4.3e-44 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
MHPNILHJ_03119 1.1e-50 yueH - - S - - - YueH-like protein
MHPNILHJ_03120 4.96e-86 yueI - - S - - - Protein of unknown function (DUF1694)
MHPNILHJ_03121 4.46e-132 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
MHPNILHJ_03122 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MHPNILHJ_03123 1.12e-285 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
MHPNILHJ_03124 1.59e-62 yuzC - - - - - - -
MHPNILHJ_03125 1.87e-11 - - - S - - - DegQ (SacQ) family
MHPNILHJ_03126 5.91e-78 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Belongs to the FPP GGPP synthase family
MHPNILHJ_03128 1.19e-315 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MHPNILHJ_03129 1.9e-146 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MHPNILHJ_03130 3.55e-77 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
MHPNILHJ_03131 8.16e-77 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
MHPNILHJ_03132 2.15e-49 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MHPNILHJ_03133 1.13e-97 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MHPNILHJ_03134 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MHPNILHJ_03135 1.42e-65 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MHPNILHJ_03136 8.6e-88 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MHPNILHJ_03137 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MHPNILHJ_03139 1.71e-215 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MHPNILHJ_03140 1.68e-232 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MHPNILHJ_03141 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MHPNILHJ_03142 7.9e-247 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
MHPNILHJ_03143 3.8e-161 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
MHPNILHJ_03144 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
MHPNILHJ_03145 2.08e-97 yufK - - S - - - Family of unknown function (DUF5366)
MHPNILHJ_03146 5.95e-92 yuxK - - S - - - protein conserved in bacteria
MHPNILHJ_03147 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
MHPNILHJ_03148 2.6e-240 yuxJ - - EGP - - - Major facilitator superfamily
MHPNILHJ_03149 2.54e-149 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
MHPNILHJ_03150 4.14e-81 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
MHPNILHJ_03151 8.41e-282 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MHPNILHJ_03152 4.65e-277 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
MHPNILHJ_03153 3.95e-51 yugE - - S - - - Domain of unknown function (DUF1871)
MHPNILHJ_03154 3.41e-192 yugF - - I - - - Hydrolase
MHPNILHJ_03155 1.53e-108 alaR - - K - - - Transcriptional regulator
MHPNILHJ_03156 2.28e-264 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
MHPNILHJ_03157 8.3e-82 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
MHPNILHJ_03158 1.28e-45 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
MHPNILHJ_03159 7.5e-283 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
MHPNILHJ_03160 8.85e-288 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
MHPNILHJ_03161 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
MHPNILHJ_03163 4.57e-90 yugN - - S - - - YugN-like family
MHPNILHJ_03164 8.97e-227 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
MHPNILHJ_03165 2.98e-36 mstX - - S - - - Membrane-integrating protein Mistic
MHPNILHJ_03166 3.56e-22 - - - - - - - -
MHPNILHJ_03167 1.95e-149 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
MHPNILHJ_03168 1.82e-293 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
MHPNILHJ_03169 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
MHPNILHJ_03170 5.54e-236 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
MHPNILHJ_03171 1.82e-52 - - - - - - - -
MHPNILHJ_03172 1.68e-174 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
MHPNILHJ_03173 4.49e-285 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
MHPNILHJ_03174 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
MHPNILHJ_03175 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
MHPNILHJ_03176 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
MHPNILHJ_03177 4.02e-126 yraA 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 DJ-1/PfpI family
MHPNILHJ_03178 4.84e-231 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
MHPNILHJ_03179 2.73e-248 yubA - - S - - - transporter activity
MHPNILHJ_03180 7.33e-184 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MHPNILHJ_03182 2.58e-72 - - - L - - - Arm DNA-binding domain
MHPNILHJ_03188 1.69e-65 - - - K - - - BRO family, N-terminal domain
MHPNILHJ_03195 6.63e-10 - - - L ko:K07451 - ko00000,ko01000,ko02048 COG1403 Restriction endonuclease
MHPNILHJ_03200 4.47e-68 - - - L - - - Terminase, small subunit
MHPNILHJ_03201 9.42e-163 terL - - S - - - Terminase
MHPNILHJ_03203 9.64e-183 - - - S - - - portal protein
MHPNILHJ_03204 2.8e-68 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
MHPNILHJ_03205 6.72e-130 - - - S - - - capsid protein
MHPNILHJ_03207 1.41e-26 - - - S - - - Phage head-tail joining protein
MHPNILHJ_03208 4.74e-43 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
MHPNILHJ_03213 0.0 - - - D - - - Phage tail tape measure protein
MHPNILHJ_03215 4.15e-125 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
MHPNILHJ_03216 0.0 - - - M - - - Pectate lyase superfamily protein
MHPNILHJ_03217 3.63e-99 - - - S - - - Domain of unknown function (DUF2479)
MHPNILHJ_03220 1.64e-57 - - - S - - - Bacteriophage holin family
MHPNILHJ_03221 2.05e-58 - - - M - - - D-alanyl-D-alanine carboxypeptidase
MHPNILHJ_03223 2.74e-21 - - - K - - - Helix-turn-helix domain
MHPNILHJ_03224 2.56e-67 - - - S - - - Protein of unknown function (DUF1433)
MHPNILHJ_03225 1.71e-304 - - - I - - - Pfam Lipase (class 3)
MHPNILHJ_03226 4.3e-54 - - - - - - - -
MHPNILHJ_03228 9.14e-26 - - - K - - - Cro/C1-type HTH DNA-binding domain
MHPNILHJ_03233 7.36e-20 - - - - - - - -
MHPNILHJ_03234 2.15e-177 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Aspartate phosphatase response regulator
MHPNILHJ_03237 2.17e-57 yjcN - - - - - - -
MHPNILHJ_03238 2.36e-47 - - - G - - - Cupin
MHPNILHJ_03239 6.24e-268 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MHPNILHJ_03240 2.27e-185 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MHPNILHJ_03241 1.97e-152 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
MHPNILHJ_03242 4.6e-119 yuaB - - - - - - -
MHPNILHJ_03243 9.65e-119 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
MHPNILHJ_03244 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
MHPNILHJ_03245 9.64e-288 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
MHPNILHJ_03246 1.21e-134 - - - S - - - MOSC domain
MHPNILHJ_03247 1.42e-102 yuaE - - S - - - DinB superfamily
MHPNILHJ_03248 7.32e-105 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
MHPNILHJ_03249 1.38e-273 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
MHPNILHJ_03250 3.55e-118 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
MHPNILHJ_03251 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHPNILHJ_03252 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
MHPNILHJ_03253 1.34e-174 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
MHPNILHJ_03254 5.89e-314 - - - E - - - Aminotransferase class I and II
MHPNILHJ_03255 1.75e-156 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
MHPNILHJ_03256 1.12e-137 yczE - - S ko:K07149 - ko00000 membrane
MHPNILHJ_03257 9.29e-168 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
MHPNILHJ_03258 5.85e-152 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
MHPNILHJ_03259 3.82e-185 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
MHPNILHJ_03260 3.54e-198 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
MHPNILHJ_03261 3.44e-130 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
MHPNILHJ_03262 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
MHPNILHJ_03263 6.46e-49 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
MHPNILHJ_03264 8.93e-96 yclD - - - - - - -
MHPNILHJ_03265 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
MHPNILHJ_03266 0.0 yclG - - M - - - Pectate lyase superfamily protein
MHPNILHJ_03268 0.0 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
MHPNILHJ_03269 1.87e-289 gerKC - - S ko:K06297 - ko00000 spore germination
MHPNILHJ_03270 5.7e-243 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
MHPNILHJ_03271 8.5e-316 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MHPNILHJ_03272 2.47e-117 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MHPNILHJ_03273 2.27e-176 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
MHPNILHJ_03274 1.22e-147 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
MHPNILHJ_03275 4.6e-169 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MHPNILHJ_03276 7.36e-272 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
MHPNILHJ_03277 1.72e-303 yxeQ - - S - - - MmgE/PrpD family
MHPNILHJ_03278 1.23e-153 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
MHPNILHJ_03279 4.84e-300 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
MHPNILHJ_03280 2.5e-162 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHPNILHJ_03281 0.0 yclK - - T - - - COG0642 Signal transduction histidine kinase
MHPNILHJ_03282 4.37e-97 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
MHPNILHJ_03285 1.28e-315 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
MHPNILHJ_03286 1.06e-208 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHPNILHJ_03287 1.4e-212 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHPNILHJ_03288 1.55e-173 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MHPNILHJ_03289 1.67e-220 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
MHPNILHJ_03290 1.98e-313 ycnB - - EGP - - - the major facilitator superfamily
MHPNILHJ_03291 4.78e-192 ycnC - - K - - - Transcriptional regulator
MHPNILHJ_03292 2.68e-172 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Nitroreductase family
MHPNILHJ_03293 2.79e-59 ycnE - - S - - - Monooxygenase
MHPNILHJ_03294 1.08e-67 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MHPNILHJ_03295 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MHPNILHJ_03296 3.02e-278 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MHPNILHJ_03297 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MHPNILHJ_03298 3.93e-189 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
MHPNILHJ_03299 3.14e-182 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHPNILHJ_03300 6.58e-128 ycnI - - S - - - protein conserved in bacteria
MHPNILHJ_03301 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
MHPNILHJ_03302 3.23e-133 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
MHPNILHJ_03303 6.5e-71 - - - - - - - -
MHPNILHJ_03304 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
MHPNILHJ_03305 1.96e-93 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
MHPNILHJ_03306 8.36e-257 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
MHPNILHJ_03307 5.81e-78 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
MHPNILHJ_03309 2.59e-175 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
MHPNILHJ_03310 1.42e-170 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
MHPNILHJ_03311 6.98e-267 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
MHPNILHJ_03312 3.25e-181 ycsI - - S - - - Belongs to the D-glutamate cyclase family
MHPNILHJ_03313 1.68e-168 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
MHPNILHJ_03314 5.16e-226 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
MHPNILHJ_03315 7.07e-162 kipR - - K - - - Transcriptional regulator
MHPNILHJ_03316 9.77e-144 ycsK - - E - - - anatomical structure formation involved in morphogenesis
MHPNILHJ_03318 6.7e-72 yczJ - - S - - - biosynthesis
MHPNILHJ_03319 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
MHPNILHJ_03320 7.28e-212 ycsN - - S - - - Oxidoreductase
MHPNILHJ_03321 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
MHPNILHJ_03322 0.0 ydaB - - IQ - - - acyl-CoA ligase
MHPNILHJ_03323 6.33e-182 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHPNILHJ_03324 1.08e-122 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
MHPNILHJ_03325 1.58e-146 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MHPNILHJ_03326 4.32e-100 ydaG - - S - - - general stress protein
MHPNILHJ_03327 9.89e-174 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
MHPNILHJ_03328 2.67e-62 ydzA - - EGP - - - Domain of unknown function (DUF3817)
MHPNILHJ_03329 3.25e-97 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
MHPNILHJ_03330 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MHPNILHJ_03331 7.77e-240 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
MHPNILHJ_03332 4.73e-183 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
MHPNILHJ_03333 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
MHPNILHJ_03334 4.51e-182 ydaM - - M - - - Glycosyl transferase family group 2
MHPNILHJ_03335 1.54e-67 ydaM - - M - - - Glycosyl transferase family group 2
MHPNILHJ_03336 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
MHPNILHJ_03337 0.0 ydaO - - E - - - amino acid
MHPNILHJ_03338 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
MHPNILHJ_03339 5.03e-80 - - - K - - - acetyltransferase
MHPNILHJ_03340 7.58e-111 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MHPNILHJ_03341 1.04e-83 - - - - - - - -
MHPNILHJ_03342 1.77e-235 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
MHPNILHJ_03345 1.06e-53 - - - - - - - -
MHPNILHJ_03346 1.47e-285 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
MHPNILHJ_03348 3.94e-45 ydaT - - - - - - -
MHPNILHJ_03349 6.73e-97 yvaD - - S - - - Family of unknown function (DUF5360)
MHPNILHJ_03350 2.18e-68 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
MHPNILHJ_03351 3.49e-172 ydbA - - P - - - EcsC protein family
MHPNILHJ_03352 1.5e-07 gsiB - - S ko:K06884 - ko00000 general stress protein
MHPNILHJ_03353 3.48e-74 ydbB - - G - - - Cupin domain
MHPNILHJ_03354 1.14e-76 ydbC - - S - - - Domain of unknown function (DUF4937
MHPNILHJ_03355 2.61e-196 ydbD - - P ko:K07217 - ko00000 Catalase
MHPNILHJ_03356 7.93e-248 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
MHPNILHJ_03357 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
MHPNILHJ_03358 4.6e-147 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
MHPNILHJ_03359 3.75e-285 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MHPNILHJ_03360 1.31e-225 ydbI - - S - - - AI-2E family transporter
MHPNILHJ_03361 7e-214 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHPNILHJ_03362 9.52e-165 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MHPNILHJ_03363 1.32e-69 ydbL - - - - - - -
MHPNILHJ_03364 4.74e-257 ydbM - - I - - - acyl-CoA dehydrogenase
MHPNILHJ_03365 2.36e-17 - - - S - - - Fur-regulated basic protein B
MHPNILHJ_03366 6.11e-15 - - - S - - - Fur-regulated basic protein A
MHPNILHJ_03367 9.92e-161 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MHPNILHJ_03368 2.25e-74 ydbP - - CO - - - Thioredoxin
MHPNILHJ_03369 7.23e-257 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
MHPNILHJ_03370 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MHPNILHJ_03371 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MHPNILHJ_03372 6.7e-93 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
MHPNILHJ_03373 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
MHPNILHJ_03374 8.15e-136 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
MHPNILHJ_03375 4.96e-72 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MHPNILHJ_03376 1.18e-230 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
MHPNILHJ_03377 3.01e-274 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MHPNILHJ_03378 6.68e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
MHPNILHJ_03379 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
MHPNILHJ_03380 9.89e-176 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
MHPNILHJ_03381 1.09e-75 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
MHPNILHJ_03382 5.79e-88 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
MHPNILHJ_03383 4.02e-238 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
MHPNILHJ_03384 3.28e-69 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
MHPNILHJ_03385 5.84e-110 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
MHPNILHJ_03386 2.67e-179 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHPNILHJ_03387 2.16e-136 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
MHPNILHJ_03388 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
MHPNILHJ_03389 1.78e-21 - - - - - - - -
MHPNILHJ_03390 4.1e-74 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
MHPNILHJ_03398 1.06e-176 - - - I ko:K01066 - ko00000,ko01000 esterase
MHPNILHJ_03399 3.54e-62 ohrB - - O - - - OsmC-like protein
MHPNILHJ_03400 7.77e-65 ohrR - - K - - - Transcriptional regulator
MHPNILHJ_03402 2.35e-213 ybfA - - K - - - FR47-like protein
MHPNILHJ_03403 2.71e-286 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
MHPNILHJ_03404 2.06e-238 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
MHPNILHJ_03405 8.87e-44 nicK - - L ko:K07467 - ko00000 Replication initiation factor
MHPNILHJ_03408 3.96e-71 - - - - - - - -
MHPNILHJ_03409 2.05e-100 - - - K - - - Transcriptional regulator
MHPNILHJ_03410 6.03e-124 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MHPNILHJ_03411 3.05e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
MHPNILHJ_03412 3.21e-144 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
MHPNILHJ_03413 2.02e-131 - - - S - - - Protein of unknown function (DUF2812)
MHPNILHJ_03414 9.59e-67 - - - K - - - Transcriptional regulator PadR-like family
MHPNILHJ_03415 1.03e-302 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MHPNILHJ_03416 4.16e-240 ydeG - - EGP - - - Major facilitator superfamily
MHPNILHJ_03417 4.07e-219 - - - S - - - Patatin-like phospholipase
MHPNILHJ_03419 0.0 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
MHPNILHJ_03420 6.38e-91 - - - E ko:K07032 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MHPNILHJ_03421 7.27e-197 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
MHPNILHJ_03422 4.15e-200 - - - S - - - SNARE associated Golgi protein
MHPNILHJ_03423 1.19e-124 yrkC - - G - - - Cupin domain
MHPNILHJ_03424 1.75e-106 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
MHPNILHJ_03425 1.73e-186 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
MHPNILHJ_03427 1.4e-238 cfr 2.1.1.224 - J ko:K15632 - ko00000,ko01000,ko01504,ko03009 Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
MHPNILHJ_03428 7.14e-63 ydeH - - - - - - -
MHPNILHJ_03429 3.65e-206 - - - S - - - Sodium Bile acid symporter family
MHPNILHJ_03430 1.96e-252 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
MHPNILHJ_03431 3.59e-78 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
MHPNILHJ_03432 6.33e-278 nhaC_1 - - C - - - antiporter
MHPNILHJ_03433 2.8e-315 - - - K ko:K00375 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
MHPNILHJ_03434 5.2e-131 paiB - - K ko:K07734 - ko00000,ko03000 Transcriptional regulator
MHPNILHJ_03435 3.52e-233 ydeR - - EGP - - - Uncharacterised MFS-type transporter YbfB
MHPNILHJ_03436 4.29e-129 ydeS - - K - - - Transcriptional regulator
MHPNILHJ_03437 4.24e-192 ydeK - - EG - - - -transporter
MHPNILHJ_03438 1.8e-316 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MHPNILHJ_03439 1.16e-62 yraD - - M ko:K06439 - ko00000 Spore coat protein
MHPNILHJ_03440 4.86e-33 yraE - - - ko:K06440 - ko00000 -
MHPNILHJ_03441 3.98e-278 adhB 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MHPNILHJ_03442 4.76e-84 yraF - - M - - - Spore coat protein
MHPNILHJ_03443 4.73e-47 yraG - - - ko:K06440 - ko00000 -
MHPNILHJ_03444 6.26e-42 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
MHPNILHJ_03445 3.37e-162 puuD - - S ko:K07010 - ko00000,ko01002 Peptidase C26
MHPNILHJ_03446 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
MHPNILHJ_03447 4.32e-117 ynaD - - J - - - Acetyltransferase (GNAT) domain
MHPNILHJ_03448 1.67e-189 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
MHPNILHJ_03449 3.1e-249 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
MHPNILHJ_03450 4.16e-263 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
MHPNILHJ_03451 5.7e-281 fabF_1 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MHPNILHJ_03452 7.19e-197 - - - K - - - Helix-turn-helix XRE-family like proteins
MHPNILHJ_03453 1.05e-156 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
MHPNILHJ_03454 2.24e-101 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
MHPNILHJ_03455 1.6e-181 bltR - - K - - - helix_turn_helix, mercury resistance
MHPNILHJ_03456 3.72e-184 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MHPNILHJ_03457 1.03e-141 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
MHPNILHJ_03458 4.97e-133 - 3.1.1.24 - S ko:K01055 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Alpha/beta hydrolase family
MHPNILHJ_03459 1.24e-208 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
MHPNILHJ_03460 1.47e-144 ydhC - - K - - - FCD
MHPNILHJ_03461 2.91e-276 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MHPNILHJ_03463 3.98e-311 pbpE - - V - - - Beta-lactamase
MHPNILHJ_03465 5.02e-127 ydhK - - M - - - Protein of unknown function (DUF1541)
MHPNILHJ_03466 1.24e-244 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
MHPNILHJ_03467 3.82e-167 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
MHPNILHJ_03468 1.12e-145 - - - K ko:K05799 - ko00000,ko03000 FCD
MHPNILHJ_03469 1.35e-264 yycB1 - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
MHPNILHJ_03470 2.88e-63 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
MHPNILHJ_03471 4.14e-63 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
MHPNILHJ_03472 1.07e-128 yvdT_1 - - K - - - Transcriptional regulator
MHPNILHJ_03473 0.0 ybeC - - E - - - amino acid
MHPNILHJ_03474 4.74e-209 ydhU - - P ko:K07217 - ko00000 Catalase
MHPNILHJ_03475 2.82e-110 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
MHPNILHJ_03476 7.98e-228 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
MHPNILHJ_03477 4.86e-313 iolT - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MHPNILHJ_03482 2.89e-84 hxlR - - K - - - transcriptional
MHPNILHJ_03483 6.52e-132 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
MHPNILHJ_03484 7.04e-121 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
MHPNILHJ_03485 2.67e-101 nucA - - M - - - Deoxyribonuclease NucA/NucB
MHPNILHJ_03486 7.34e-86 nin - - S - - - Competence protein J (ComJ)
MHPNILHJ_03487 0.0 yckE 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MHPNILHJ_03488 7.52e-65 - - - S - - - Protein of unknown function (DUF2680)
MHPNILHJ_03489 3.65e-94 yckC - - S - - - membrane
MHPNILHJ_03490 2.62e-278 fdh 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MHPNILHJ_03491 9.85e-281 yciC - - S - - - GTPases (G3E family)
MHPNILHJ_03492 1.41e-49 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
MHPNILHJ_03493 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MHPNILHJ_03494 1.64e-72 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
MHPNILHJ_03495 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
MHPNILHJ_03496 4.86e-235 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
MHPNILHJ_03497 7.58e-286 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
MHPNILHJ_03498 1.05e-309 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MHPNILHJ_03499 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
MHPNILHJ_03500 1.53e-213 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
MHPNILHJ_03501 8.28e-178 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
MHPNILHJ_03502 9.05e-231 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
MHPNILHJ_03503 1.43e-134 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MHPNILHJ_03504 3.35e-288 - - - G ko:K08191,ko:K08194 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
MHPNILHJ_03505 1.69e-164 - 4.2.1.118 - G ko:K15652 ko00400,ko01110,ko01130,map00400,map01110,map01130 ko00000,ko00001,ko01000 Xylose isomerase-like TIM barrel
MHPNILHJ_03506 3.54e-189 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MHPNILHJ_03507 6.25e-144 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
MHPNILHJ_03508 2.37e-304 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
MHPNILHJ_03509 5.9e-183 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
MHPNILHJ_03510 3.18e-147 ycgF - - E - - - Lysine exporter protein LysE YggA
MHPNILHJ_03511 6.38e-97 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
MHPNILHJ_03512 0.0 mdr - - EGP - - - the major facilitator superfamily
MHPNILHJ_03513 1.28e-225 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
MHPNILHJ_03514 1.05e-15 - - - S - - - RDD family
MHPNILHJ_03515 1.04e-53 ycgB - - - - - - -
MHPNILHJ_03516 8.16e-287 ycgA - - S - - - Membrane
MHPNILHJ_03517 3.87e-262 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
MHPNILHJ_03518 4.54e-207 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
MHPNILHJ_03519 3.48e-185 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
MHPNILHJ_03520 7.07e-290 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
MHPNILHJ_03522 2.43e-265 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
MHPNILHJ_03523 2.74e-245 yceH - - P - - - Belongs to the TelA family
MHPNILHJ_03524 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
MHPNILHJ_03525 4.28e-178 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
MHPNILHJ_03526 3.36e-136 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
MHPNILHJ_03527 7.32e-136 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
MHPNILHJ_03528 9.56e-139 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
MHPNILHJ_03529 8.68e-231 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MHPNILHJ_03530 1.38e-173 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MHPNILHJ_03531 1.15e-169 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MHPNILHJ_03532 5.72e-214 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
MHPNILHJ_03533 1.86e-62 - - - K - - - Virulence activator alpha C-term
MHPNILHJ_03534 1.5e-62 - - - S - - - Domain of unknown function (DUF4188)
MHPNILHJ_03535 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
MHPNILHJ_03536 6.52e-174 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
MHPNILHJ_03537 3.74e-221 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
MHPNILHJ_03538 5.55e-116 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
MHPNILHJ_03539 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MHPNILHJ_03540 2.82e-300 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MHPNILHJ_03541 4.62e-210 ycdA - - S - - - Domain of unknown function (DUF5105)
MHPNILHJ_03542 9.13e-211 yccK - - C - - - Aldo keto reductase
MHPNILHJ_03543 2.44e-245 yccF - - K ko:K07039 - ko00000 SEC-C motif
MHPNILHJ_03544 1.44e-141 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
MHPNILHJ_03545 3.35e-125 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
MHPNILHJ_03546 1.26e-306 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
MHPNILHJ_03547 7.85e-247 ycbU - - E - - - Selenocysteine lyase
MHPNILHJ_03548 1.4e-153 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MHPNILHJ_03549 1.44e-155 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MHPNILHJ_03550 5.03e-35 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MHPNILHJ_03551 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
MHPNILHJ_03552 9.01e-103 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
MHPNILHJ_03553 4.68e-82 ycbP - - S - - - Protein of unknown function (DUF2512)
MHPNILHJ_03554 3.23e-75 ydfQ - - CO - - - Thioredoxin
MHPNILHJ_03555 7.71e-82 ydfP - - S ko:K15977 - ko00000 DoxX
MHPNILHJ_03556 2.41e-232 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
MHPNILHJ_03557 1.91e-142 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
MHPNILHJ_03558 4.28e-198 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MHPNILHJ_03559 9.53e-38 - - - L - - - Transposase
MHPNILHJ_03560 3.3e-33 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
MHPNILHJ_03561 9.37e-158 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
MHPNILHJ_03562 2.43e-197 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
MHPNILHJ_03563 2.63e-264 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MHPNILHJ_03564 5.3e-239 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
MHPNILHJ_03565 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
MHPNILHJ_03566 3.97e-228 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
MHPNILHJ_03567 8.9e-317 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
MHPNILHJ_03568 4.24e-248 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
MHPNILHJ_03569 5.27e-266 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MHPNILHJ_03570 1.78e-239 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
MHPNILHJ_03571 9.76e-52 ybfN - - - - - - -
MHPNILHJ_03572 4.85e-191 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
MHPNILHJ_03573 3.37e-110 ybfM - - S - - - SNARE associated Golgi protein
MHPNILHJ_03574 9.04e-120 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MHPNILHJ_03575 8.16e-265 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MHPNILHJ_03576 5.91e-239 ypjH - - C ko:K08317 - ko00000,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
MHPNILHJ_03577 1.14e-105 - - - K - - - Helix-turn-helix XRE-family like proteins
MHPNILHJ_03579 7.87e-262 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
MHPNILHJ_03580 1.43e-23 - - - S - - - Protein of unknown function (DUF2651)
MHPNILHJ_03581 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
MHPNILHJ_03582 3.07e-208 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
MHPNILHJ_03583 3.62e-22 - - - S - - - Protein of unknown function (DUF2651)
MHPNILHJ_03585 0.0 ybeC - - E - - - amino acid
MHPNILHJ_03586 6.22e-52 ybyB - - - - - - -
MHPNILHJ_03587 8.46e-86 yqeB - - - - - - -
MHPNILHJ_03588 3.92e-18 yqeB - - - - - - -
MHPNILHJ_03589 2.48e-52 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
MHPNILHJ_03590 3.66e-103 - - - S - - - Domain of unknown function (DUF4879)
MHPNILHJ_03591 6.5e-33 - - - - - - - -
MHPNILHJ_03592 1.98e-231 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
MHPNILHJ_03593 2.36e-242 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
MHPNILHJ_03594 9.05e-207 yfiL - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
MHPNILHJ_03595 5.76e-132 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
MHPNILHJ_03596 3.42e-230 - - - T - - - COG4585 Signal transduction histidine kinase
MHPNILHJ_03597 3.75e-119 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
MHPNILHJ_03598 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
MHPNILHJ_03599 6.3e-90 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MHPNILHJ_03600 6.65e-66 - - - S ko:K06518 - ko00000,ko02000 LrgA family
MHPNILHJ_03601 3.49e-134 yxaC - - M - - - effector of murein hydrolase
MHPNILHJ_03602 5.5e-202 dkgB - - S - - - Aldo/keto reductase family
MHPNILHJ_03603 8.77e-168 ybdO - - S - - - Domain of unknown function (DUF4885)
MHPNILHJ_03604 5.33e-125 ybdN - - - - - - -
MHPNILHJ_03605 5.91e-68 - - - S - - - ABC-2 family transporter protein
MHPNILHJ_03606 6.58e-222 - - - O - - - growth
MHPNILHJ_03607 2.66e-27 - - - S - - - peptidyl-tyrosine sulfation
MHPNILHJ_03608 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MHPNILHJ_03609 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MHPNILHJ_03610 7.78e-292 ybbR - - S - - - protein conserved in bacteria
MHPNILHJ_03611 9e-188 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MHPNILHJ_03612 1.7e-146 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
MHPNILHJ_03613 6.6e-99 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MHPNILHJ_03619 4.36e-98 ybbK - - S - - - Protein of unknown function (DUF523)
MHPNILHJ_03620 1.14e-106 ybbJ - - J - - - acetyltransferase
MHPNILHJ_03621 1.28e-205 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MHPNILHJ_03622 2e-301 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MHPNILHJ_03623 4.35e-300 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
MHPNILHJ_03624 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
MHPNILHJ_03625 2.2e-291 ybbC - - S - - - protein conserved in bacteria
MHPNILHJ_03626 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
MHPNILHJ_03627 3.89e-216 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
MHPNILHJ_03628 5.16e-225 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHPNILHJ_03629 1.21e-223 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHPNILHJ_03630 1.41e-129 ybbA - - S ko:K07017 - ko00000 Putative esterase
MHPNILHJ_03631 7.81e-216 ybaS - - S - - - Na -dependent transporter
MHPNILHJ_03632 1.24e-284 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
MHPNILHJ_03633 1.33e-254 - 1.1.1.14, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00008 ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
MHPNILHJ_03634 1.75e-227 suhB 3.1.3.25, 3.1.3.7 - G ko:K01082,ko:K01092 ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070 ko00000,ko00001,ko00002,ko01000,ko03016 inositol monophosphate 1-phosphatase activity
MHPNILHJ_03635 1.22e-311 gabT 2.6.1.19 - E ko:K00823 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MHPNILHJ_03636 2.1e-270 glcP1 - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
MHPNILHJ_03639 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
MHPNILHJ_03640 1.29e-298 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
MHPNILHJ_03641 4.9e-76 yflT - - S - - - Heat induced stress protein YflT
MHPNILHJ_03642 9.83e-33 - - - S - - - Protein of unknown function (DUF3212)
MHPNILHJ_03643 9.68e-231 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
MHPNILHJ_03644 1.34e-259 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
MHPNILHJ_03645 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MHPNILHJ_03646 3.06e-249 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
MHPNILHJ_03647 8.36e-89 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
MHPNILHJ_03648 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MHPNILHJ_03649 4.84e-256 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
MHPNILHJ_03650 1.59e-210 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
MHPNILHJ_03651 3.69e-165 yfmS - - NT - - - chemotaxis protein
MHPNILHJ_03652 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MHPNILHJ_03653 2.1e-306 yfnA - - E ko:K03294 - ko00000 amino acid
MHPNILHJ_03654 4.78e-272 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
MHPNILHJ_03655 5.43e-227 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
MHPNILHJ_03656 6.55e-272 yfnE - - S - - - Glycosyltransferase like family 2
MHPNILHJ_03657 7.97e-222 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
MHPNILHJ_03658 5.59e-219 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
MHPNILHJ_03659 1.4e-186 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
MHPNILHJ_03660 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
MHPNILHJ_03662 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
MHPNILHJ_03663 2.78e-251 yetN - - S - - - Protein of unknown function (DUF3900)
MHPNILHJ_03664 2.58e-239 yetM - - CH - - - FAD binding domain
MHPNILHJ_03665 3.05e-110 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
MHPNILHJ_03666 5.15e-135 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
MHPNILHJ_03667 2.59e-73 - - - H - - - riboflavin kinase activity
MHPNILHJ_03668 7.84e-29 - - - S - - - Uncharacterized small protein (DUF2292)
MHPNILHJ_03669 2.4e-185 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MHPNILHJ_03670 2.87e-82 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MHPNILHJ_03671 3.06e-70 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
MHPNILHJ_03672 1.26e-147 yetF - - S - - - membrane
MHPNILHJ_03674 8e-114 yesJ - - K - - - Acetyltransferase (GNAT) family
MHPNILHJ_03675 4.26e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
MHPNILHJ_03676 1.34e-60 cotJB - - S ko:K06333 - ko00000 CotJB protein
MHPNILHJ_03677 1.32e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
MHPNILHJ_03678 2.48e-138 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
MHPNILHJ_03680 4.43e-162 yeeN - - K - - - transcriptional regulatory protein
MHPNILHJ_03681 6.14e-152 - - - L ko:K21487 - ko00000,ko01000,ko02048 Belongs to the WXG100 family
MHPNILHJ_03682 1.69e-257 - - - L ko:K21487 - ko00000,ko01000,ko02048 nucleic acid phosphodiester bond hydrolysis
MHPNILHJ_03683 2.48e-66 - - - S - - - Protein of unknown function, DUF600
MHPNILHJ_03684 2.35e-73 - - - S - - - Protein of unknown function, DUF600
MHPNILHJ_03685 5.92e-51 - - - S - - - Protein of unknown function, DUF600
MHPNILHJ_03686 3.92e-175 cylB - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
MHPNILHJ_03687 2.88e-204 cylA - - V ko:K01990,ko:K09695,ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
MHPNILHJ_03688 0.0 - - - L ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
MHPNILHJ_03689 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MHPNILHJ_03690 8.56e-217 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MHPNILHJ_03691 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MHPNILHJ_03692 1.01e-189 yerO - - K - - - Transcriptional regulator
MHPNILHJ_03693 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MHPNILHJ_03694 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MHPNILHJ_03695 1.81e-60 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MHPNILHJ_03696 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MHPNILHJ_03697 7.98e-156 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
MHPNILHJ_03698 6.11e-231 yerI - - S - - - homoserine kinase type II (protein kinase fold)
MHPNILHJ_03699 1.59e-285 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
MHPNILHJ_03700 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MHPNILHJ_03701 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
MHPNILHJ_03702 5.04e-163 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
MHPNILHJ_03703 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
MHPNILHJ_03704 2.03e-67 yerC - - S - - - protein conserved in bacteria
MHPNILHJ_03705 2.74e-243 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
MHPNILHJ_03706 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
MHPNILHJ_03707 2.05e-33 - - - S - - - Protein of unknown function (DUF2892)
MHPNILHJ_03708 3.96e-173 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
MHPNILHJ_03709 4.48e-81 - - - K - - - helix_turn_helix ASNC type
MHPNILHJ_03710 7.41e-294 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
MHPNILHJ_03711 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
MHPNILHJ_03712 3.89e-132 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MHPNILHJ_03713 4.2e-241 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
MHPNILHJ_03714 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MHPNILHJ_03715 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MHPNILHJ_03716 6.14e-163 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MHPNILHJ_03717 8.96e-51 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MHPNILHJ_03718 2.2e-162 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
MHPNILHJ_03719 1.05e-313 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MHPNILHJ_03720 2.42e-282 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MHPNILHJ_03721 1.87e-107 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MHPNILHJ_03722 7.68e-39 yebG - - S - - - NETI protein
MHPNILHJ_03723 7.62e-120 yebE - - S - - - UPF0316 protein
MHPNILHJ_03725 3.28e-163 yebC - - M - - - Membrane
MHPNILHJ_03726 1.01e-268 pbuG - - S ko:K06901 - ko00000,ko02000 permease
MHPNILHJ_03727 8.71e-313 - - - S - - - Domain of unknown function (DUF4179)
MHPNILHJ_03728 3.03e-118 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MHPNILHJ_03729 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
MHPNILHJ_03730 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
MHPNILHJ_03731 1e-254 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
MHPNILHJ_03732 7.99e-226 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
MHPNILHJ_03733 3.12e-192 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MHPNILHJ_03734 2.56e-307 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
MHPNILHJ_03735 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
MHPNILHJ_03736 9.6e-47 ydjO - - S - - - Cold-inducible protein YdjO
MHPNILHJ_03738 1.51e-189 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
MHPNILHJ_03739 7.91e-83 ydjM - - M - - - Lytic transglycolase
MHPNILHJ_03740 7.9e-246 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
MHPNILHJ_03741 1.08e-112 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MHPNILHJ_03742 5.52e-184 rsiV - - S - - - Protein of unknown function (DUF3298)
MHPNILHJ_03743 0.0 oatA - - I - - - Acyltransferase family
MHPNILHJ_03744 4.64e-200 ydjI - - S - - - virion core protein (lumpy skin disease virus)
MHPNILHJ_03745 3.97e-156 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
MHPNILHJ_03746 6.45e-222 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MHPNILHJ_03747 4.36e-143 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
MHPNILHJ_03748 1.21e-39 yjdJ - - S - - - Domain of unknown function (DUF4306)
MHPNILHJ_03749 1.93e-217 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
MHPNILHJ_03750 6.05e-290 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
MHPNILHJ_03751 6.58e-253 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
MHPNILHJ_03752 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
MHPNILHJ_03753 2.21e-81 - - - - - - - -
MHPNILHJ_03755 0.0 ykuG - - M - - - Putative peptidoglycan binding domain
MHPNILHJ_03756 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MHPNILHJ_03757 1.24e-57 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MHPNILHJ_03758 9.24e-162 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
MHPNILHJ_03759 1.11e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
MHPNILHJ_03760 2.61e-157 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MHPNILHJ_03761 1.72e-29 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MHPNILHJ_03762 1.51e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MHPNILHJ_03763 2.95e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
MHPNILHJ_03764 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
MHPNILHJ_03765 2.83e-239 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MHPNILHJ_03766 5.74e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MHPNILHJ_03767 2.69e-158 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
MHPNILHJ_03768 1.44e-109 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
MHPNILHJ_03769 4.4e-221 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MHPNILHJ_03770 2.08e-208 ygxA - - S - - - Nucleotidyltransferase-like
MHPNILHJ_03771 1.1e-73 ygzB - - S - - - UPF0295 protein
MHPNILHJ_03772 6.8e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
MHPNILHJ_03773 7.73e-109 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
MHPNILHJ_03774 1.27e-309 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
MHPNILHJ_03775 1.76e-237 ygaE - - S - - - Membrane
MHPNILHJ_03776 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
MHPNILHJ_03777 2.32e-135 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
MHPNILHJ_03778 1.4e-49 ygaB - - S - - - YgaB-like protein
MHPNILHJ_03779 9.58e-06 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
MHPNILHJ_03780 1.73e-169 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHPNILHJ_03781 1.47e-49 yfhS - - - - - - -
MHPNILHJ_03782 3.84e-258 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
MHPNILHJ_03783 4.29e-229 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
MHPNILHJ_03784 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
MHPNILHJ_03785 4.51e-235 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
MHPNILHJ_03786 6.02e-213 - - - S - - - Alpha/beta hydrolase family
MHPNILHJ_03787 2.82e-48 yfhL - - S - - - SdpI/YhfL protein family
MHPNILHJ_03788 1.14e-112 yfhK - - T - - - Bacterial SH3 domain homologues
MHPNILHJ_03789 1.49e-58 yfhJ - - S - - - WVELL protein
MHPNILHJ_03790 1.4e-206 mpr - - M - - - Belongs to the peptidase S1B family
MHPNILHJ_03792 1.93e-266 yfhI - - EGP - - - -transporter
MHPNILHJ_03793 3.93e-61 yfhH - - S - - - Protein of unknown function (DUF1811)
MHPNILHJ_03794 1.95e-177 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
MHPNILHJ_03795 3.2e-210 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
MHPNILHJ_03797 6.01e-33 yfhD - - S - - - YfhD-like protein
MHPNILHJ_03798 3.09e-133 yfhC - - C - - - nitroreductase
MHPNILHJ_03799 1.27e-193 yfhB - - S - - - PhzF family
MHPNILHJ_03800 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MHPNILHJ_03801 1.48e-103 yfiV - - K - - - transcriptional
MHPNILHJ_03802 0.0 yfiU - - EGP - - - the major facilitator superfamily
MHPNILHJ_03803 2.04e-122 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
MHPNILHJ_03804 1.37e-59 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
MHPNILHJ_03805 2.39e-223 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
MHPNILHJ_03806 1.83e-128 - 1.6.5.2 - S ko:K00355 ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
MHPNILHJ_03807 1e-119 padR - - K - - - transcriptional
MHPNILHJ_03808 1.49e-89 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MHPNILHJ_03809 2.12e-99 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MHPNILHJ_03810 5.91e-199 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
MHPNILHJ_03811 7.86e-82 yfiD3 - - S - - - DoxX
MHPNILHJ_03812 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
MHPNILHJ_03813 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
MHPNILHJ_03814 0.0 - - - M - - - Peptidase_G2, IMC autoproteolytic cleavage domain
MHPNILHJ_03815 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MHPNILHJ_03816 3.67e-177 glvR - - F ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
MHPNILHJ_03817 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MHPNILHJ_03818 3.29e-22 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
MHPNILHJ_03819 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
MHPNILHJ_03820 3.32e-302 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MHPNILHJ_03821 7.82e-265 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MHPNILHJ_03822 9.85e-238 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MHPNILHJ_03823 2.95e-239 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MHPNILHJ_03824 2.86e-102 yfjM - - S - - - Psort location Cytoplasmic, score
MHPNILHJ_03825 7.85e-241 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MHPNILHJ_03826 1.83e-60 - - - S - - - YfzA-like protein
MHPNILHJ_03834 0.0 - - - KLT - - - Protein kinase domain
MHPNILHJ_03835 5.62e-307 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
MHPNILHJ_03836 3.87e-94 - - - O ko:K20486 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000,ko01002 Subtilase family
MHPNILHJ_03837 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MHPNILHJ_03838 5.07e-201 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MHPNILHJ_03839 5.27e-235 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
MHPNILHJ_03841 3.41e-178 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
MHPNILHJ_03842 4.19e-197 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
MHPNILHJ_03843 7.99e-37 yfjT - - - - - - -
MHPNILHJ_03844 1.09e-277 yfkA - - S - - - YfkB-like domain
MHPNILHJ_03845 6.79e-185 yfkC - - M - - - Mechanosensitive ion channel
MHPNILHJ_03846 3.01e-181 yfkD - - S - - - YfkD-like protein
MHPNILHJ_03847 1.34e-235 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
MHPNILHJ_03848 3.65e-272 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
MHPNILHJ_03849 7.59e-183 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
MHPNILHJ_03850 4.68e-64 yfkI - - S - - - gas vesicle protein
MHPNILHJ_03851 5.02e-105 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MHPNILHJ_03852 1.28e-39 yfkK - - S - - - Belongs to the UPF0435 family
MHPNILHJ_03853 1.23e-245 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
MHPNILHJ_03854 5.75e-165 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MHPNILHJ_03855 1.61e-205 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MHPNILHJ_03856 2.99e-228 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
MHPNILHJ_03857 7.82e-118 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
MHPNILHJ_03858 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
MHPNILHJ_03859 5.49e-235 yibE - - S - - - YibE/F-like protein
MHPNILHJ_03860 1.06e-160 yibF - - S - - - YibE/F-like protein
MHPNILHJ_03861 1.34e-154 frp - - C - - - nitroreductase
MHPNILHJ_03862 2.03e-162 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
MHPNILHJ_03863 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
MHPNILHJ_03864 7.43e-312 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MHPNILHJ_03865 1.85e-53 ydgB - - S - - - Spore germination protein gerPA/gerPF
MHPNILHJ_03866 6.73e-51 ydgA - - S - - - Spore germination protein gerPA/gerPF
MHPNILHJ_03867 2.68e-100 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
MHPNILHJ_03868 3.87e-80 ydhN1 - - S - - - Domain of unknown function (DUF1992)
MHPNILHJ_03869 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
MHPNILHJ_03870 8.21e-97 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
MHPNILHJ_03871 3.41e-313 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
MHPNILHJ_03872 1.05e-174 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
MHPNILHJ_03873 1.38e-65 yflH - - S - - - Protein of unknown function (DUF3243)
MHPNILHJ_03874 5.69e-26 yflI - - - - - - -
MHPNILHJ_03875 5.84e-21 yflJ - - S - - - Protein of unknown function (DUF2639)
MHPNILHJ_03876 1.9e-153 yflK - - S - - - protein conserved in bacteria
MHPNILHJ_03877 4.43e-56 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
MHPNILHJ_03878 7.02e-269 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
MHPNILHJ_03879 3.39e-183 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
MHPNILHJ_03880 4.33e-282 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
MHPNILHJ_03881 1.36e-217 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
MHPNILHJ_03882 4.96e-148 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
MHPNILHJ_03883 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
MHPNILHJ_03884 5.54e-104 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
MHPNILHJ_03885 1.38e-175 - - - M - - - cell wall anchor domain
MHPNILHJ_03886 2.14e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
MHPNILHJ_03887 8.58e-79 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
MHPNILHJ_03888 3.84e-257 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
MHPNILHJ_03889 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
MHPNILHJ_03890 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MHPNILHJ_03891 3.64e-249 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
MHPNILHJ_03892 1.85e-245 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
MHPNILHJ_03893 1.96e-157 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MHPNILHJ_03894 1.23e-110 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MHPNILHJ_03895 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MHPNILHJ_03896 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
MHPNILHJ_03897 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
MHPNILHJ_03898 9.32e-92 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MHPNILHJ_03899 9.69e-171 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MHPNILHJ_03900 1.92e-113 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
MHPNILHJ_03901 4.65e-149 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
MHPNILHJ_03902 3.77e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MHPNILHJ_03903 3.99e-123 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
MHPNILHJ_03904 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MHPNILHJ_03905 2.04e-159 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MHPNILHJ_03906 6.68e-103 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MHPNILHJ_03907 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MHPNILHJ_03908 2.53e-140 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
MHPNILHJ_03909 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MHPNILHJ_03910 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MHPNILHJ_03911 9.87e-45 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
MHPNILHJ_03912 9.47e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MHPNILHJ_03913 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MHPNILHJ_03914 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MHPNILHJ_03915 9.55e-286 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MHPNILHJ_03916 3.62e-220 ybaC - - S - - - Alpha/beta hydrolase family
MHPNILHJ_03917 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
MHPNILHJ_03918 1.02e-143 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MHPNILHJ_03919 3.68e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
MHPNILHJ_03920 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MHPNILHJ_03921 9.5e-201 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MHPNILHJ_03922 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MHPNILHJ_03923 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MHPNILHJ_03924 1.69e-151 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MHPNILHJ_03925 1.38e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MHPNILHJ_03926 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
MHPNILHJ_03927 1.92e-51 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MHPNILHJ_03928 1.04e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MHPNILHJ_03929 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MHPNILHJ_03930 2.58e-120 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MHPNILHJ_03931 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MHPNILHJ_03932 1.08e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MHPNILHJ_03933 1.05e-119 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MHPNILHJ_03934 2.38e-74 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MHPNILHJ_03935 4.54e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MHPNILHJ_03936 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
MHPNILHJ_03937 2.1e-94 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
MHPNILHJ_03938 1.82e-294 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MHPNILHJ_03939 2.51e-157 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MHPNILHJ_03940 3.16e-180 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
MHPNILHJ_03941 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MHPNILHJ_03942 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
MHPNILHJ_03943 1.54e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MHPNILHJ_03944 4.61e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MHPNILHJ_03945 4.94e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MHPNILHJ_03946 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
MHPNILHJ_03947 6.9e-196 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MHPNILHJ_03948 1.06e-184 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MHPNILHJ_03949 8.86e-175 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MHPNILHJ_03950 3.42e-179 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MHPNILHJ_03951 3.79e-101 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MHPNILHJ_03952 1.49e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
MHPNILHJ_03953 4.46e-179 ybaJ - - Q - - - Methyltransferase domain
MHPNILHJ_03955 2.28e-99 ybaK - - S - - - Protein of unknown function (DUF2521)
MHPNILHJ_03956 4.3e-168 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
MHPNILHJ_03957 4.58e-247 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MHPNILHJ_03958 1.95e-102 gerD - - - ko:K06294 - ko00000 -
MHPNILHJ_03959 1.25e-134 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
MHPNILHJ_03960 1.09e-174 pdaB - - G - - - Polysaccharide deacetylase
MHPNILHJ_03961 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
MHPNILHJ_03962 8.33e-230 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MHPNILHJ_03963 9.99e-39 yazB - - K - - - transcriptional
MHPNILHJ_03964 4.38e-113 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MHPNILHJ_03965 1.88e-80 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MHPNILHJ_03966 1.62e-196 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MHPNILHJ_03967 3.18e-191 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
MHPNILHJ_03968 5.14e-137 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
MHPNILHJ_03969 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MHPNILHJ_03970 1.79e-216 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
MHPNILHJ_03971 4.24e-193 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
MHPNILHJ_03972 7.52e-205 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MHPNILHJ_03973 6.69e-177 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MHPNILHJ_03974 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MHPNILHJ_03975 4.29e-119 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
MHPNILHJ_03976 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MHPNILHJ_03977 1.18e-229 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
MHPNILHJ_03978 8.92e-165 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
MHPNILHJ_03979 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
MHPNILHJ_03982 3.54e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
MHPNILHJ_03983 2.42e-74 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
MHPNILHJ_03984 5.13e-129 yabQ - - S - - - spore cortex biosynthesis protein
MHPNILHJ_03985 5.47e-66 yabP - - S - - - Sporulation protein YabP
MHPNILHJ_03986 8.51e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
MHPNILHJ_03987 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
MHPNILHJ_03988 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MHPNILHJ_03989 1.09e-116 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
MHPNILHJ_03990 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MHPNILHJ_03991 5.24e-53 yabK - - S - - - Peptide ABC transporter permease
MHPNILHJ_03992 4.99e-136 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MHPNILHJ_03993 1.4e-133 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MHPNILHJ_03994 7.08e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MHPNILHJ_03995 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MHPNILHJ_03996 4.23e-64 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
MHPNILHJ_03997 7.5e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
MHPNILHJ_03998 5.43e-195 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
MHPNILHJ_03999 2.25e-205 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MHPNILHJ_04000 7.31e-38 sspF - - S ko:K06423 - ko00000 DNA topological change
MHPNILHJ_04001 5.32e-53 veg - - S - - - protein conserved in bacteria
MHPNILHJ_04002 1.46e-186 yabG - - S ko:K06436 - ko00000 peptidase
MHPNILHJ_04003 9.41e-200 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MHPNILHJ_04004 3.1e-125 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MHPNILHJ_04005 3.55e-288 yabE - - T - - - protein conserved in bacteria
MHPNILHJ_04006 1.44e-182 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
MHPNILHJ_04007 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MHPNILHJ_04008 3.56e-57 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
MHPNILHJ_04009 9.82e-202 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MHPNILHJ_04010 1.64e-62 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
MHPNILHJ_04011 3.28e-177 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
MHPNILHJ_04012 2.53e-55 yabA - - L - - - Involved in initiation control of chromosome replication
MHPNILHJ_04013 6.33e-189 yaaT - - S - - - stage 0 sporulation protein
MHPNILHJ_04014 8.67e-230 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
MHPNILHJ_04015 2.86e-92 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
MHPNILHJ_04016 5.03e-73 yaaQ - - S - - - protein conserved in bacteria
MHPNILHJ_04017 7.14e-141 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MHPNILHJ_04018 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
MHPNILHJ_04019 5.18e-225 yaaN - - P - - - Belongs to the TelA family
MHPNILHJ_04020 1.05e-129 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
MHPNILHJ_04021 1.5e-40 csfB - - S - - - Inhibitor of sigma-G Gin
MHPNILHJ_04022 2.16e-48 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
MHPNILHJ_04023 7.67e-43 yaaL - - S - - - Protein of unknown function (DUF2508)
MHPNILHJ_04024 6e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MHPNILHJ_04025 6.9e-52 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MHPNILHJ_04026 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MHPNILHJ_04027 5.61e-108 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MHPNILHJ_04028 4.62e-125 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
MHPNILHJ_04029 8.84e-272 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
MHPNILHJ_04030 3.32e-148 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
MHPNILHJ_04031 1.4e-154 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
MHPNILHJ_04033 2.36e-251 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
MHPNILHJ_04034 4.16e-281 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MHPNILHJ_04035 2.35e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MHPNILHJ_04036 7.47e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MHPNILHJ_04037 1.03e-315 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MHPNILHJ_04038 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MHPNILHJ_04039 1.64e-224 yaaC - - S - - - YaaC-like Protein
MHPNILHJ_04040 4.78e-191 M1-574 - - T - - - Transcriptional regulatory protein, C terminal
MHPNILHJ_04041 0.0 ywpD - - T - - - Histidine kinase
MHPNILHJ_04042 9.29e-92 M1-820 - - Q - - - Collagen triple helix repeat (20 copies)
MHPNILHJ_04043 2.81e-67 - - - Q - - - calcium- and calmodulin-responsive adenylate cyclase activity
MHPNILHJ_04047 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHPNILHJ_04048 9.3e-53 - - - S - - - COG NOG14552 non supervised orthologous group

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)