ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
COCFCCGP_00001 1.01e-109 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
COCFCCGP_00002 3.43e-282 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
COCFCCGP_00003 2.2e-91 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
COCFCCGP_00004 3.66e-85 esbA - - S - - - Family of unknown function (DUF5322)
COCFCCGP_00005 6.71e-92 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
COCFCCGP_00006 1.13e-221 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
COCFCCGP_00007 9.15e-264 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
COCFCCGP_00008 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
COCFCCGP_00009 0.0 FbpA - - K - - - Fibronectin-binding protein
COCFCCGP_00010 2.95e-207 - - - S - - - EDD domain protein, DegV family
COCFCCGP_00011 7.49e-124 - - - - - - - -
COCFCCGP_00012 3.04e-154 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
COCFCCGP_00013 2.07e-202 gspA - - M - - - family 8
COCFCCGP_00014 5.98e-206 - - - S - - - Alpha beta hydrolase
COCFCCGP_00015 7.5e-122 - - - K - - - Acetyltransferase (GNAT) domain
COCFCCGP_00016 4.98e-307 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
COCFCCGP_00017 1.02e-51 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
COCFCCGP_00018 2.99e-218 yvgN - - C - - - Aldo keto reductase
COCFCCGP_00019 7.79e-204 rlrB - - K - - - LysR substrate binding domain protein
COCFCCGP_00020 2.91e-109 - - - C - - - Flavodoxin
COCFCCGP_00021 8.73e-104 - - - S - - - Cupin domain
COCFCCGP_00022 9.49e-98 - - - S - - - UPF0756 membrane protein
COCFCCGP_00023 2.9e-309 - - - U - - - Belongs to the major facilitator superfamily
COCFCCGP_00024 2.39e-98 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
COCFCCGP_00025 5.51e-316 yhdP - - S - - - Transporter associated domain
COCFCCGP_00026 0.0 ubiB - - S ko:K03688 - ko00000 ABC1 family
COCFCCGP_00027 1.43e-185 - - - S - - - DUF218 domain
COCFCCGP_00028 3.39e-90 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
COCFCCGP_00029 1.3e-78 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
COCFCCGP_00030 6.28e-73 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
COCFCCGP_00031 0.0 uvrA2 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC, A subunit
COCFCCGP_00032 2.04e-158 - - - S - - - SNARE associated Golgi protein
COCFCCGP_00033 1.27e-291 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
COCFCCGP_00034 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
COCFCCGP_00036 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
COCFCCGP_00037 4.32e-200 endA - - V ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
COCFCCGP_00038 2.27e-49 int2 - - L - - - Belongs to the 'phage' integrase family
COCFCCGP_00046 2.18e-43 - - - S ko:K06919 - ko00000 D5 N terminal like
COCFCCGP_00051 3.05e-39 - - - V - - - HNH nucleases
COCFCCGP_00054 2.96e-188 - - - S - - - Phage Terminase
COCFCCGP_00055 8.19e-98 - - - S - - - Phage portal protein
COCFCCGP_00056 2.68e-75 - - - S - - - peptidase activity
COCFCCGP_00057 9.59e-10 - - - - - - - -
COCFCCGP_00064 5.26e-100 - - - D - - - domain protein
COCFCCGP_00070 5.97e-18 - - - S - - - COG5546 Small integral membrane protein
COCFCCGP_00071 1.23e-164 - - - M - - - Glycosyl hydrolases family 25
COCFCCGP_00075 0.0 - - - I - - - Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
COCFCCGP_00076 1.49e-285 - - - L ko:K07484 - ko00000 Transposase IS66 family
COCFCCGP_00078 4.24e-35 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
COCFCCGP_00079 1.07e-60 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
COCFCCGP_00080 4.95e-86 - - - K - - - HxlR-like helix-turn-helix
COCFCCGP_00081 1.15e-69 - - - S - - - macrophage migration inhibitory factor
COCFCCGP_00082 2.89e-68 - - - C - - - Oxidoreductase
COCFCCGP_00083 3.41e-27 - - - C - - - Oxidoreductase
COCFCCGP_00084 2.25e-103 - - - C - - - Oxidoreductase
COCFCCGP_00087 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
COCFCCGP_00088 1.85e-202 - - - S - - - Calcineurin-like phosphoesterase
COCFCCGP_00091 1.55e-143 - - - - - - - -
COCFCCGP_00092 0.0 - - - EGP - - - Major Facilitator
COCFCCGP_00093 0.0 - - - P ko:K07085 - ko00000 Predicted Permease Membrane Region
COCFCCGP_00094 1.1e-171 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
COCFCCGP_00095 3.54e-165 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
COCFCCGP_00096 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
COCFCCGP_00097 5.27e-197 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
COCFCCGP_00098 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
COCFCCGP_00099 5.75e-112 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
COCFCCGP_00101 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
COCFCCGP_00102 5.27e-235 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
COCFCCGP_00103 0.0 - - - S - - - Bacterial membrane protein, YfhO
COCFCCGP_00104 3.04e-172 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
COCFCCGP_00105 6.27e-216 - - - I - - - alpha/beta hydrolase fold
COCFCCGP_00106 2.47e-273 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
COCFCCGP_00107 1.54e-138 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
COCFCCGP_00108 2.14e-142 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
COCFCCGP_00109 6.12e-165 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
COCFCCGP_00110 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
COCFCCGP_00111 2.5e-162 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
COCFCCGP_00112 3.33e-66 yjdJ - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
COCFCCGP_00113 1.1e-125 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
COCFCCGP_00114 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
COCFCCGP_00115 5.12e-266 yacL - - S - - - domain protein
COCFCCGP_00116 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
COCFCCGP_00117 3.58e-93 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
COCFCCGP_00118 1.05e-174 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
COCFCCGP_00119 9.18e-31 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
COCFCCGP_00120 2.9e-31 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
COCFCCGP_00121 1.1e-126 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
COCFCCGP_00122 1.39e-92 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
COCFCCGP_00123 8.31e-158 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
COCFCCGP_00124 1.86e-288 aadAT - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 Aminotransferase, class I
COCFCCGP_00126 6.61e-314 - - - M - - - Glycosyl transferase family group 2
COCFCCGP_00127 3.88e-76 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
COCFCCGP_00128 3.25e-162 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
COCFCCGP_00129 3.6e-107 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
COCFCCGP_00130 2.46e-72 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
COCFCCGP_00131 2.91e-65 - - - - - - - -
COCFCCGP_00133 2.94e-65 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
COCFCCGP_00134 2.79e-75 XK27_06915 - - K ko:K10947 - ko00000,ko03000 transcriptional regulator PadR family
COCFCCGP_00135 8.01e-129 - - - S - - - Protein of unknown function (DUF1700)
COCFCCGP_00136 3.1e-168 - - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
COCFCCGP_00137 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
COCFCCGP_00138 4.63e-255 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
COCFCCGP_00139 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
COCFCCGP_00140 9.33e-48 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
COCFCCGP_00141 6.21e-119 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
COCFCCGP_00142 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
COCFCCGP_00143 5.87e-62 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
COCFCCGP_00144 1.41e-141 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
COCFCCGP_00145 4.67e-52 - - - S - - - Protein of unknown function (DUF2508)
COCFCCGP_00146 2.14e-147 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
COCFCCGP_00147 2.83e-69 yaaQ - - S - - - Cyclic-di-AMP receptor
COCFCCGP_00148 1.29e-235 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
COCFCCGP_00149 3.71e-76 yabA - - L - - - Involved in initiation control of chromosome replication
COCFCCGP_00150 3.7e-199 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
COCFCCGP_00151 6.09e-176 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
COCFCCGP_00152 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
COCFCCGP_00153 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
COCFCCGP_00154 1.87e-221 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
COCFCCGP_00155 6.02e-247 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
COCFCCGP_00156 3.63e-157 - - - O - - - Bacterial dnaA protein
COCFCCGP_00157 8.8e-17 yjeA 3.5.1.104 - G ko:K22278 - ko00000,ko01000 polysaccharide deacetylase
COCFCCGP_00158 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
COCFCCGP_00159 0.0 xylB 2.7.1.17, 2.7.1.53 - G ko:K00854,ko:K00880 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the FGGY kinase family
COCFCCGP_00160 3.05e-198 - - - KT ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 YcbB domain
COCFCCGP_00161 3.21e-244 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
COCFCCGP_00162 3.94e-221 arcC 2.7.2.2 - E ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 ko00000,ko00001,ko01000 Belongs to the carbamate kinase family
COCFCCGP_00163 3.18e-206 - - - EG - - - EamA-like transporter family
COCFCCGP_00164 7.03e-134 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
COCFCCGP_00165 1.6e-82 - - - S - - - Cupredoxin-like domain
COCFCCGP_00166 2.2e-65 - - - S - - - Cupredoxin-like domain
COCFCCGP_00167 0.0 copA 3.6.3.3, 3.6.3.5, 3.6.3.54 - P ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
COCFCCGP_00168 1.23e-110 - - - - - - - -
COCFCCGP_00170 2.13e-74 - - - - - - - -
COCFCCGP_00171 4.95e-92 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
COCFCCGP_00172 2.53e-22 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
COCFCCGP_00173 2.46e-141 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
COCFCCGP_00177 1.96e-24 - - - S - - - Phage gp6-like head-tail connector protein
COCFCCGP_00178 7.5e-238 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
COCFCCGP_00179 1.62e-177 - - - S - - - Phage portal protein
COCFCCGP_00180 8.98e-247 terL - - S - - - overlaps another CDS with the same product name
COCFCCGP_00181 2.63e-33 terS - - L - - - Phage terminase, small subunit
COCFCCGP_00182 5.75e-42 - - - L - - - HNH endonuclease
COCFCCGP_00185 4.76e-109 - - - S ko:K06919 - ko00000 Phage plasmid primase, P4
COCFCCGP_00186 3.16e-11 - - - S - - - Primase C terminal 1 (PriCT-1)
COCFCCGP_00189 1e-09 - - - S - - - Helix-turn-helix domain
COCFCCGP_00190 6.71e-07 - - - S - - - sequence-specific DNA binding
COCFCCGP_00191 1.67e-146 int2 - - L - - - Belongs to the 'phage' integrase family
COCFCCGP_00192 9.23e-138 - - - - - - - -
COCFCCGP_00193 1.26e-293 - - - M - - - domain protein
COCFCCGP_00194 1.93e-305 - - - M - - - domain protein
COCFCCGP_00195 1.64e-75 - - - - - - - -
COCFCCGP_00196 9.5e-239 ampC - - V - - - Beta-lactamase
COCFCCGP_00197 1.25e-304 arcA 3.5.3.6 - E ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 ko00000,ko00001,ko01000 Arginine
COCFCCGP_00198 1.77e-103 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
COCFCCGP_00199 0.0 arcD - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
COCFCCGP_00200 1.97e-297 potE - - U ko:K03756,ko:K03758 - ko00000,ko02000 Amino acid permease
COCFCCGP_00201 4.87e-173 - - - S ko:K07009 - ko00000 CobB/CobQ-like glutamine amidotransferase domain
COCFCCGP_00202 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Mur ligase, middle domain
COCFCCGP_00203 6.8e-140 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
COCFCCGP_00204 1.73e-248 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
COCFCCGP_00205 2.17e-207 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
COCFCCGP_00206 1.55e-250 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
COCFCCGP_00207 6.33e-294 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
COCFCCGP_00208 6.68e-150 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
COCFCCGP_00209 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
COCFCCGP_00210 6.71e-246 yibE - - S - - - overlaps another CDS with the same product name
COCFCCGP_00211 4.71e-166 yibF - - S - - - overlaps another CDS with the same product name
COCFCCGP_00212 2.3e-293 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
COCFCCGP_00213 4.63e-162 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
COCFCCGP_00214 1.26e-29 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
COCFCCGP_00215 1.07e-95 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
COCFCCGP_00216 6.84e-121 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
COCFCCGP_00217 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
COCFCCGP_00218 1.3e-212 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
COCFCCGP_00219 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
COCFCCGP_00220 1.05e-88 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
COCFCCGP_00221 1.76e-45 ywzB - - S - - - Protein of unknown function (DUF1146)
COCFCCGP_00222 1.05e-308 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
COCFCCGP_00223 2.57e-227 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
COCFCCGP_00224 4.61e-44 - - - S - - - Protein of unknown function (DUF2969)
COCFCCGP_00225 3.86e-281 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
COCFCCGP_00226 1.17e-61 gcsH2 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 glycine cleavage
COCFCCGP_00227 6.32e-275 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
COCFCCGP_00228 1.03e-212 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
COCFCCGP_00229 9.16e-91 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
COCFCCGP_00230 7.99e-293 - - - V - - - MatE
COCFCCGP_00231 0.0 potE - - E - - - Amino Acid
COCFCCGP_00232 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
COCFCCGP_00233 1.38e-155 csrR - - K - - - response regulator
COCFCCGP_00234 7.21e-39 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
COCFCCGP_00235 2.89e-129 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
COCFCCGP_00236 9.69e-274 ylbM - - S - - - Belongs to the UPF0348 family
COCFCCGP_00237 1.1e-179 yqeM - - Q - - - Methyltransferase
COCFCCGP_00238 1.9e-79 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
COCFCCGP_00239 3.6e-146 yqeK - - H - - - Hydrolase, HD family
COCFCCGP_00240 2.43e-158 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
COCFCCGP_00241 5.4e-63 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
COCFCCGP_00242 5.44e-279 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
COCFCCGP_00243 3.17e-124 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
COCFCCGP_00244 2.23e-73 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
COCFCCGP_00245 1.82e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
COCFCCGP_00246 1.07e-110 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
COCFCCGP_00247 9.62e-219 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
COCFCCGP_00248 3.31e-275 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
COCFCCGP_00249 2.82e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
COCFCCGP_00250 5.91e-129 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
COCFCCGP_00251 1.58e-203 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
COCFCCGP_00252 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
COCFCCGP_00253 3.26e-150 - - - S - - - Protein of unknown function (DUF1275)
COCFCCGP_00254 6.48e-154 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
COCFCCGP_00255 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
COCFCCGP_00256 8.55e-46 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
COCFCCGP_00257 7.39e-64 - - - S - - - Bacterial toxin of type II toxin-antitoxin system, YafQ
COCFCCGP_00258 5.47e-151 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
COCFCCGP_00259 2.95e-75 ytpP - - CO - - - Thioredoxin
COCFCCGP_00260 3.23e-75 - - - S - - - Small secreted protein
COCFCCGP_00261 1.21e-213 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
COCFCCGP_00262 9.43e-233 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
COCFCCGP_00263 5.88e-126 tagE3 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
COCFCCGP_00264 6.79e-183 tagE3 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
COCFCCGP_00265 1.43e-311 - 2.1.1.72, 3.1.21.3 AA10,CBM73 M ko:K01154,ko:K02014,ko:K03933,ko:K07316 - ko00000,ko01000,ko02000,ko02048 domain protein
COCFCCGP_00266 7.51e-77 - 2.1.1.72, 3.1.21.3 AA10,CBM73 M ko:K01154,ko:K02014,ko:K03933,ko:K07316 - ko00000,ko01000,ko02000,ko02048 domain protein
COCFCCGP_00267 3.31e-37 - - - S - - - YSIRK type signal peptide
COCFCCGP_00268 1.85e-157 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
COCFCCGP_00269 3.84e-278 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
COCFCCGP_00270 2.7e-175 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
COCFCCGP_00271 4.99e-101 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
COCFCCGP_00273 3.96e-178 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
COCFCCGP_00274 0.0 yhaN - - L - - - AAA domain
COCFCCGP_00275 2.62e-282 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
COCFCCGP_00276 5.33e-77 yheA - - S - - - Belongs to the UPF0342 family
COCFCCGP_00277 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
COCFCCGP_00278 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
COCFCCGP_00279 2.15e-194 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
COCFCCGP_00280 3.88e-213 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
COCFCCGP_00282 1.49e-54 - - - - - - - -
COCFCCGP_00283 9.3e-61 - - - - - - - -
COCFCCGP_00284 1.62e-277 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 dihydropteroate synthase
COCFCCGP_00285 2.97e-136 folQ 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
COCFCCGP_00286 8.17e-285 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
COCFCCGP_00287 3.36e-136 folE 2.7.6.3, 3.5.4.16 - F ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase 1
COCFCCGP_00288 4.71e-114 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
COCFCCGP_00289 6.82e-72 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
COCFCCGP_00291 6.21e-57 - - - - - - - -
COCFCCGP_00292 1.05e-153 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
COCFCCGP_00293 1.52e-43 - - - - - - - -
COCFCCGP_00294 1.63e-207 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
COCFCCGP_00295 8.42e-237 rbsR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
COCFCCGP_00296 3.08e-146 - - - - - - - -
COCFCCGP_00297 3.06e-150 dgk2 - - F - - - deoxynucleoside kinase
COCFCCGP_00298 1.11e-224 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
COCFCCGP_00299 4.4e-112 - - - T - - - Belongs to the universal stress protein A family
COCFCCGP_00300 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
COCFCCGP_00301 4.82e-194 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
COCFCCGP_00304 1.69e-229 - - - I - - - Diacylglycerol kinase catalytic
COCFCCGP_00305 9.99e-44 ykzG - - S - - - Belongs to the UPF0356 family
COCFCCGP_00306 6.08e-102 - - - - - - - -
COCFCCGP_00307 1.38e-132 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
COCFCCGP_00308 2.44e-267 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
COCFCCGP_00309 9.42e-232 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
COCFCCGP_00310 2.13e-311 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
COCFCCGP_00311 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
COCFCCGP_00312 7.04e-63 yktA - - S - - - Belongs to the UPF0223 family
COCFCCGP_00313 3.52e-177 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
COCFCCGP_00314 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
COCFCCGP_00315 7.54e-284 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
COCFCCGP_00316 6.37e-60 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
COCFCCGP_00317 6.8e-129 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
COCFCCGP_00318 3.05e-116 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
COCFCCGP_00319 4.99e-251 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
COCFCCGP_00320 3.4e-138 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
COCFCCGP_00321 7.1e-116 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
COCFCCGP_00322 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
COCFCCGP_00323 9.21e-200 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
COCFCCGP_00324 1.44e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
COCFCCGP_00325 1.74e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
COCFCCGP_00326 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
COCFCCGP_00327 3.58e-208 - - - S - - - Tetratricopeptide repeat
COCFCCGP_00328 4.94e-288 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
COCFCCGP_00329 5.54e-303 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
COCFCCGP_00330 2.06e-297 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
COCFCCGP_00331 2.01e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
COCFCCGP_00332 1.11e-78 - - - S - - - mazG nucleotide pyrophosphohydrolase
COCFCCGP_00333 2.44e-20 - - - - - - - -
COCFCCGP_00334 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
COCFCCGP_00335 3.8e-316 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
COCFCCGP_00336 3.39e-226 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
COCFCCGP_00337 3.87e-200 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
COCFCCGP_00338 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
COCFCCGP_00339 1.46e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
COCFCCGP_00340 1.79e-121 - - - - - - - -
COCFCCGP_00342 7.77e-159 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
COCFCCGP_00343 2.88e-270 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
COCFCCGP_00344 4.18e-147 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
COCFCCGP_00345 2.7e-47 ynzC - - S - - - UPF0291 protein
COCFCCGP_00346 1.6e-40 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
COCFCCGP_00347 7.51e-152 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
COCFCCGP_00348 5.9e-182 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
COCFCCGP_00349 6.79e-65 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
COCFCCGP_00350 2.92e-233 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COCFCCGP_00351 3.54e-184 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
COCFCCGP_00352 3.14e-197 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
COCFCCGP_00353 2.21e-167 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
COCFCCGP_00354 4.23e-123 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
COCFCCGP_00355 7.45e-182 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
COCFCCGP_00356 1.18e-177 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
COCFCCGP_00357 5.46e-297 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
COCFCCGP_00358 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
COCFCCGP_00359 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
COCFCCGP_00360 1.1e-108 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
COCFCCGP_00361 1.68e-274 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
COCFCCGP_00362 5.93e-60 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
COCFCCGP_00363 1.96e-65 ylxQ - - J - - - ribosomal protein
COCFCCGP_00364 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
COCFCCGP_00365 1.38e-77 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
COCFCCGP_00366 1.21e-215 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
COCFCCGP_00367 3.13e-225 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
COCFCCGP_00368 3.03e-83 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
COCFCCGP_00369 0.0 - - - E ko:K03294 - ko00000 amino acid
COCFCCGP_00370 5.46e-183 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
COCFCCGP_00371 5.33e-119 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
COCFCCGP_00372 2.17e-52 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
COCFCCGP_00373 1.21e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
COCFCCGP_00374 0.0 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
COCFCCGP_00375 4.23e-76 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
COCFCCGP_00376 4.94e-285 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
COCFCCGP_00377 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
COCFCCGP_00378 1.57e-168 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
COCFCCGP_00379 1.81e-50 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
COCFCCGP_00380 4.72e-241 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
COCFCCGP_00381 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
COCFCCGP_00382 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
COCFCCGP_00383 1.05e-77 yloU - - S - - - Asp23 family, cell envelope-related function
COCFCCGP_00384 1.1e-34 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
COCFCCGP_00385 6.95e-159 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
COCFCCGP_00386 5.46e-152 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
COCFCCGP_00387 3.75e-212 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
COCFCCGP_00388 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
COCFCCGP_00389 4.26e-168 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
COCFCCGP_00390 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
COCFCCGP_00391 8.26e-222 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
COCFCCGP_00392 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
COCFCCGP_00393 4.44e-273 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
COCFCCGP_00394 6.66e-43 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
COCFCCGP_00395 4.37e-148 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
COCFCCGP_00396 9e-72 - - - - - - - -
COCFCCGP_00397 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
COCFCCGP_00398 1.52e-98 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
COCFCCGP_00399 1.69e-192 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
COCFCCGP_00400 6.95e-205 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
COCFCCGP_00401 4.02e-58 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
COCFCCGP_00402 1.09e-309 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
COCFCCGP_00403 1.61e-192 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
COCFCCGP_00404 2.24e-92 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
COCFCCGP_00405 2.27e-93 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
COCFCCGP_00406 1.22e-147 - - - J - - - 2'-5' RNA ligase superfamily
COCFCCGP_00407 1.29e-257 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
COCFCCGP_00408 3.84e-170 - - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
COCFCCGP_00409 5.07e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
COCFCCGP_00410 1.77e-72 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
COCFCCGP_00411 2.68e-67 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
COCFCCGP_00412 1.34e-144 - - - K - - - Transcriptional regulator
COCFCCGP_00416 4.21e-116 - - - S - - - Protein conserved in bacteria
COCFCCGP_00417 1.47e-223 - - - - - - - -
COCFCCGP_00418 4.87e-203 - - - - - - - -
COCFCCGP_00419 1.54e-67 yitW - - S - - - Iron-sulfur cluster assembly protein
COCFCCGP_00420 2.83e-131 msrA 1.8.4.11 - C ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
COCFCCGP_00421 4.65e-195 - - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
COCFCCGP_00422 1.28e-18 - - - - - - - -
COCFCCGP_00423 8.1e-281 araT 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
COCFCCGP_00424 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
COCFCCGP_00425 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
COCFCCGP_00426 7.13e-227 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
COCFCCGP_00427 1.18e-30 - - - S - - - Protein of unknown function (DUF3042)
COCFCCGP_00428 7.66e-88 yqhL - - P - - - Rhodanese-like protein
COCFCCGP_00429 1.02e-234 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
COCFCCGP_00430 7.07e-48 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
COCFCCGP_00431 1.38e-59 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
COCFCCGP_00432 1.43e-16 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
COCFCCGP_00433 9.34e-130 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
COCFCCGP_00434 1.53e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
COCFCCGP_00435 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
COCFCCGP_00436 0.0 - - - S - - - membrane
COCFCCGP_00437 1.33e-91 yneR - - S - - - Belongs to the HesB IscA family
COCFCCGP_00440 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
COCFCCGP_00441 1.53e-241 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
COCFCCGP_00442 7.93e-219 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
COCFCCGP_00443 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
COCFCCGP_00444 3.68e-125 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
COCFCCGP_00445 0.0 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
COCFCCGP_00446 5.75e-103 yabR - - J ko:K07571 - ko00000 RNA binding
COCFCCGP_00447 7.15e-75 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
COCFCCGP_00448 1.18e-51 yabO - - J - - - S4 domain protein
COCFCCGP_00449 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
COCFCCGP_00450 7.98e-132 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
COCFCCGP_00451 2.7e-145 - - - S - - - (CBS) domain
COCFCCGP_00452 2.06e-188 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
COCFCCGP_00453 2.75e-309 codA 3.5.4.1 - F ko:K01485 ko00240,ko00330,ko01100,map00240,map00330,map01100 ko00000,ko00001,ko01000 cytosine deaminase
COCFCCGP_00454 0.0 - - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
COCFCCGP_00455 1.3e-82 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
COCFCCGP_00456 1.54e-269 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
COCFCCGP_00457 1.88e-80 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
COCFCCGP_00458 2.63e-08 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
COCFCCGP_00459 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
COCFCCGP_00460 7.14e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
COCFCCGP_00461 1e-47 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
COCFCCGP_00462 0.0 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
COCFCCGP_00463 3.55e-214 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
COCFCCGP_00464 5.48e-195 - - - D - - - Domain of Unknown Function (DUF1542)
COCFCCGP_00465 2.12e-32 - - - D - - - Domain of Unknown Function (DUF1542)
COCFCCGP_00466 8.02e-159 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
COCFCCGP_00467 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
COCFCCGP_00468 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
COCFCCGP_00469 1.06e-203 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
COCFCCGP_00470 4.93e-123 lemA - - S ko:K03744 - ko00000 LemA family
COCFCCGP_00471 2.71e-112 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
COCFCCGP_00472 1.51e-154 - - - G - - - Belongs to the phosphoglycerate mutase family
COCFCCGP_00473 2.53e-206 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
COCFCCGP_00474 6.08e-179 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
COCFCCGP_00475 1.37e-189 - - - G - - - Right handed beta helix region
COCFCCGP_00476 0.0 pps 2.7.9.2 - H ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
COCFCCGP_00477 4.29e-162 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
COCFCCGP_00478 1.86e-212 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
COCFCCGP_00479 3.07e-301 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
COCFCCGP_00480 9.43e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
COCFCCGP_00481 5.29e-300 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
COCFCCGP_00482 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
COCFCCGP_00483 1.04e-85 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
COCFCCGP_00484 9.28e-89 ywiB - - S - - - Domain of unknown function (DUF1934)
COCFCCGP_00485 4.82e-188 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 biotin lipoate A B protein ligase
COCFCCGP_00486 0.0 ywfO - - S ko:K06885 - ko00000 HD domain protein
COCFCCGP_00487 1.89e-189 yidA - - S - - - hydrolase
COCFCCGP_00488 1.6e-100 - - - - - - - -
COCFCCGP_00489 1.01e-228 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
COCFCCGP_00490 2.6e-313 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
COCFCCGP_00491 5.24e-191 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
COCFCCGP_00492 4.12e-164 - - - U ko:K02075 - ko00000,ko00002,ko02000 ABC 3 transport family
COCFCCGP_00493 2.31e-156 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
COCFCCGP_00494 1.66e-214 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
COCFCCGP_00495 6.91e-234 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
COCFCCGP_00496 5.87e-50 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
COCFCCGP_00497 1.22e-197 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
COCFCCGP_00498 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
COCFCCGP_00499 5.1e-121 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
COCFCCGP_00500 1.49e-227 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
COCFCCGP_00501 2.6e-234 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
COCFCCGP_00502 1.55e-109 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
COCFCCGP_00503 1.8e-81 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
COCFCCGP_00504 1.08e-218 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
COCFCCGP_00505 2.14e-189 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
COCFCCGP_00506 2.14e-234 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
COCFCCGP_00507 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
COCFCCGP_00508 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
COCFCCGP_00509 2.09e-265 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
COCFCCGP_00510 1.69e-278 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
COCFCCGP_00511 2.2e-160 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
COCFCCGP_00512 1.85e-201 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
COCFCCGP_00513 1.58e-301 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
COCFCCGP_00514 1.16e-41 - - - S - - - Protein of unknown function (DUF2929)
COCFCCGP_00515 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
COCFCCGP_00516 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
COCFCCGP_00517 1.08e-214 yitL - - S ko:K00243 - ko00000 S1 domain
COCFCCGP_00518 2.35e-211 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
COCFCCGP_00519 3.67e-86 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
COCFCCGP_00520 1.95e-177 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
COCFCCGP_00521 1.35e-135 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
COCFCCGP_00522 6.81e-163 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
COCFCCGP_00523 2.65e-133 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
COCFCCGP_00524 7.6e-246 - - - S - - - Helix-turn-helix domain
COCFCCGP_00525 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
COCFCCGP_00526 2.15e-83 - - - M - - - Lysin motif
COCFCCGP_00527 3.8e-153 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
COCFCCGP_00528 1e-272 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
COCFCCGP_00529 0.0 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
COCFCCGP_00530 1.6e-54 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
COCFCCGP_00531 9.5e-301 XK27_05225 - - S - - - Tetratricopeptide repeat protein
COCFCCGP_00532 4.94e-287 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
COCFCCGP_00533 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
COCFCCGP_00534 3.61e-247 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
COCFCCGP_00535 3.38e-119 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
COCFCCGP_00536 2.59e-144 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
COCFCCGP_00537 6.38e-196 WQ51_01275 - - S - - - EDD domain protein, DegV family
COCFCCGP_00538 4.79e-221 - - - E - - - lipolytic protein G-D-S-L family
COCFCCGP_00539 4.05e-141 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
COCFCCGP_00540 1.33e-47 yozE - - S - - - Belongs to the UPF0346 family
COCFCCGP_00541 1.99e-204 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
COCFCCGP_00542 2.05e-180 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
COCFCCGP_00543 7.84e-207 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
COCFCCGP_00544 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
COCFCCGP_00545 7.89e-212 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
COCFCCGP_00546 1.9e-139 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
COCFCCGP_00547 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
COCFCCGP_00548 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
COCFCCGP_00549 2.41e-111 - - - F - - - NUDIX domain
COCFCCGP_00550 5.18e-222 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
COCFCCGP_00551 0.0 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
COCFCCGP_00552 2.51e-182 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
COCFCCGP_00553 1.08e-289 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
COCFCCGP_00554 1.31e-243 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
COCFCCGP_00556 4.72e-134 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
COCFCCGP_00557 1.83e-21 - - - - - - - -
COCFCCGP_00559 1.94e-218 whiA - - K ko:K09762 - ko00000 May be required for sporulation
COCFCCGP_00560 5.73e-239 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
COCFCCGP_00561 8.05e-208 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
COCFCCGP_00562 5.51e-316 steT - - E ko:K03294 - ko00000 amino acid
COCFCCGP_00563 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
COCFCCGP_00564 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
COCFCCGP_00565 4.16e-19 - - - - - - - -
COCFCCGP_00566 3.57e-150 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
COCFCCGP_00567 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
COCFCCGP_00568 2.85e-114 ykhA 3.1.2.20 - I ko:K01073 - ko00000,ko01000 Thioesterase superfamily
COCFCCGP_00569 1.2e-131 - - - ET ko:K02030 - ko00000,ko00002,ko02000 PFAM extracellular solute-binding protein, family 3
COCFCCGP_00570 1.27e-40 - - - ET ko:K02030 - ko00000,ko00002,ko02000 PFAM extracellular solute-binding protein, family 3
COCFCCGP_00571 1.9e-277 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
COCFCCGP_00572 2.38e-222 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
COCFCCGP_00573 1.43e-208 lutA - - C ko:K18928 - ko00000 Cysteine-rich domain
COCFCCGP_00574 0.0 lutB - - C ko:K18929 - ko00000 4Fe-4S dicluster domain
COCFCCGP_00575 5.04e-175 lutC - - S ko:K00782 - ko00000 LUD domain
COCFCCGP_00576 1.79e-214 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
COCFCCGP_00577 5.93e-237 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
COCFCCGP_00578 3.31e-200 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
COCFCCGP_00579 2.79e-226 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
COCFCCGP_00580 1.88e-68 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
COCFCCGP_00581 2.11e-66 - - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain protein
COCFCCGP_00582 1.58e-238 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
COCFCCGP_00583 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
COCFCCGP_00584 5e-124 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
COCFCCGP_00585 1.73e-148 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
COCFCCGP_00586 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
COCFCCGP_00587 6.65e-145 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
COCFCCGP_00588 4.03e-299 - - - EGP - - - Major Facilitator
COCFCCGP_00589 8.81e-89 - - - K - - - Transcriptional regulator
COCFCCGP_00590 2.63e-53 - - - - - - - -
COCFCCGP_00591 0.0 ydaO - - E - - - amino acid
COCFCCGP_00592 0.0 - - - E - - - amino acid
COCFCCGP_00593 3.11e-106 - - - S ko:K19055 - ko00000,ko01000,ko03016 YbaK proline--tRNA ligase associated domain protein
COCFCCGP_00594 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
COCFCCGP_00595 1.83e-59 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
COCFCCGP_00597 1.34e-146 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
COCFCCGP_00598 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
COCFCCGP_00599 1.39e-231 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
COCFCCGP_00600 6.98e-286 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
COCFCCGP_00601 1.82e-181 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
COCFCCGP_00602 3.49e-175 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
COCFCCGP_00603 1.81e-290 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
COCFCCGP_00604 5.14e-170 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
COCFCCGP_00605 2.12e-253 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
COCFCCGP_00606 3.02e-135 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
COCFCCGP_00607 1.27e-162 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
COCFCCGP_00608 9.29e-290 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
COCFCCGP_00609 5.36e-97 - - - - - - - -
COCFCCGP_00610 3.67e-255 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
COCFCCGP_00611 1.36e-35 - - - - - - - -
COCFCCGP_00612 0.0 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
COCFCCGP_00613 6.08e-213 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
COCFCCGP_00614 0.0 - - - L - - - PFAM plasmid pRiA4b ORF-3 family protein
COCFCCGP_00615 1.35e-263 adh 1.1.1.1 - C ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding alcohol dehydrogenase family protein
COCFCCGP_00616 2.87e-144 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
COCFCCGP_00617 5.46e-207 mleR - - K - - - LysR family
COCFCCGP_00618 0.0 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
COCFCCGP_00619 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
COCFCCGP_00620 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
COCFCCGP_00621 1.21e-165 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
COCFCCGP_00622 1.3e-217 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
COCFCCGP_00623 5.04e-157 citR - - K - - - sugar-binding domain protein
COCFCCGP_00624 2.7e-222 mae 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme, NAD binding domain
COCFCCGP_00625 9.38e-188 citC 6.2.1.22 - H ko:K01910 ko02020,map02020 ko00000,ko00001,ko01000 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
COCFCCGP_00626 2.56e-56 citD - - C ko:K01646 ko02020,map02020 ko00000,ko00001 Covalent carrier of the coenzyme of citrate lyase
COCFCCGP_00627 3.29e-204 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
COCFCCGP_00628 0.0 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
COCFCCGP_00629 1.56e-193 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
COCFCCGP_00630 1.03e-142 - - - I - - - Alpha/beta hydrolase family
COCFCCGP_00631 7.21e-205 - - - K - - - LysR family
COCFCCGP_00632 0.0 - - - S - - - Putative threonine/serine exporter
COCFCCGP_00633 2.22e-151 - 3.2.2.27 - L ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Uracil-DNA glycosylase
COCFCCGP_00634 0.0 qacA - - EGP - - - Major Facilitator
COCFCCGP_00635 1.93e-241 - - - I - - - Alpha beta
COCFCCGP_00636 6.53e-133 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
COCFCCGP_00637 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
COCFCCGP_00639 2.24e-205 yjbO 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
COCFCCGP_00640 1.91e-153 - - - S - - - Domain of unknown function (DUF4811)
COCFCCGP_00641 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
COCFCCGP_00642 1.26e-96 - - - K - - - MerR HTH family regulatory protein
COCFCCGP_00643 9.15e-72 - - - - - - - -
COCFCCGP_00644 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
COCFCCGP_00645 8.69e-277 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
COCFCCGP_00646 2.11e-140 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
COCFCCGP_00647 1.06e-142 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
COCFCCGP_00648 3.85e-195 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
COCFCCGP_00649 1.14e-172 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
COCFCCGP_00650 4.83e-108 - - - T - - - Belongs to the universal stress protein A family
COCFCCGP_00651 2.34e-142 - - - S - - - VIT family
COCFCCGP_00652 7.33e-152 - - - S - - - membrane
COCFCCGP_00653 2.85e-212 - - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
COCFCCGP_00654 7.76e-160 mntR - - K ko:K03709 - ko00000,ko03000 iron dependent repressor
COCFCCGP_00655 2.17e-43 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
COCFCCGP_00656 2.09e-166 - - - S - - - Putative threonine/serine exporter
COCFCCGP_00657 5.02e-105 - - - S - - - Threonine/Serine exporter, ThrE
COCFCCGP_00658 2.79e-153 - - - I - - - phosphatase
COCFCCGP_00660 0.0 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
COCFCCGP_00661 7.78e-150 dgk2 - - F - - - deoxynucleoside kinase
COCFCCGP_00669 3.85e-45 - - - - - - - -
COCFCCGP_00670 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
COCFCCGP_00671 1.45e-55 - - - - - - - -
COCFCCGP_00672 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
COCFCCGP_00673 2.71e-280 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
COCFCCGP_00674 1.94e-95 tag1 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
COCFCCGP_00675 0.0 - - - EGP - - - Major Facilitator
COCFCCGP_00676 1.25e-111 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
COCFCCGP_00677 1.72e-303 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
COCFCCGP_00678 8.28e-135 - - - V - - - VanZ like family
COCFCCGP_00679 7.03e-33 - - - - - - - -
COCFCCGP_00680 5.03e-111 - - - S - - - Short repeat of unknown function (DUF308)
COCFCCGP_00681 3.77e-102 - - - S - - - Psort location Cytoplasmic, score
COCFCCGP_00682 0.0 umuC - - L ko:K03502 - ko00000,ko03400 impB/mucB/samB family C-terminal domain
COCFCCGP_00683 4.63e-101 hsp - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
COCFCCGP_00684 1.57e-197 yeaE - - S - - - Aldo keto
COCFCCGP_00685 1.31e-136 - - - M - - - LysM domain protein
COCFCCGP_00686 0.0 - - - EP - - - Psort location Cytoplasmic, score
COCFCCGP_00687 2.73e-148 - - - M - - - LysM domain protein
COCFCCGP_00688 3.48e-192 - - - O - - - Uncharacterized protein family (UPF0051)
COCFCCGP_00689 1.88e-142 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
COCFCCGP_00690 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
COCFCCGP_00691 1.63e-312 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
COCFCCGP_00692 1.74e-125 - - - K - - - Acetyltransferase (GNAT) domain
COCFCCGP_00693 6.41e-236 - - - M - - - lysozyme activity
COCFCCGP_00694 1.26e-41 - - - S - - - Bacteriophage holin of superfamily 6 (Holin_LLH)
COCFCCGP_00695 1.75e-71 - - - S - - - Bacteriophage holin family
COCFCCGP_00696 3.92e-151 - - - E - - - GDSL-like Lipase/Acylhydrolase
COCFCCGP_00697 2.14e-05 - - - - - - - -
COCFCCGP_00698 0.0 - - - M - - - Prophage endopeptidase tail
COCFCCGP_00699 6.15e-188 - - - S - - - phage tail
COCFCCGP_00700 0.0 - - - D - - - Phage tail tape measure protein
COCFCCGP_00701 6.42e-80 - - - - - - - -
COCFCCGP_00702 4.62e-70 - - - S - - - Phage tail assembly chaperone protein, TAC
COCFCCGP_00703 1.65e-133 - - - S - - - Phage tail tube protein
COCFCCGP_00704 4.5e-28 - - - S - - - Protein of unknown function (DUF3168)
COCFCCGP_00705 5.09e-89 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
COCFCCGP_00706 1.48e-65 - - - - - - - -
COCFCCGP_00707 1.13e-84 - - - S - - - Phage gp6-like head-tail connector protein
COCFCCGP_00708 3.54e-199 - - - - - - - -
COCFCCGP_00709 3.63e-130 - - - S - - - Domain of unknown function (DUF4355)
COCFCCGP_00710 9.38e-45 - - - S - - - YjcQ protein
COCFCCGP_00712 1.18e-298 - - - S - - - Phage Mu protein F like protein
COCFCCGP_00713 0.0 - - - S - - - Phage portal protein
COCFCCGP_00714 1.11e-280 yqaT - - S ko:K06909 - ko00000 Phage terminase, large subunit
COCFCCGP_00715 1.04e-11 yqaT - - S ko:K06909 - ko00000 Phage terminase, large subunit
COCFCCGP_00716 1.6e-90 - - - L ko:K07474 - ko00000 Terminase small subunit
COCFCCGP_00718 1.2e-103 - - - S - - - Phage transcriptional regulator, ArpU family
COCFCCGP_00724 1.17e-77 - - - S - - - VRR_NUC
COCFCCGP_00728 6.82e-74 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
COCFCCGP_00729 1.17e-135 ypsA - - S - - - Belongs to the UPF0398 family
COCFCCGP_00730 7.01e-153 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
COCFCCGP_00731 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
COCFCCGP_00732 5.69e-207 - - - EG - - - EamA-like transporter family
COCFCCGP_00733 1.75e-161 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
COCFCCGP_00734 9.09e-113 ypmB - - S - - - Protein conserved in bacteria
COCFCCGP_00735 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
COCFCCGP_00736 5.16e-220 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
COCFCCGP_00737 1.71e-217 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
COCFCCGP_00738 3.37e-273 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
COCFCCGP_00739 8.91e-248 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
COCFCCGP_00740 5.52e-119 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
COCFCCGP_00741 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
COCFCCGP_00742 2.43e-241 galR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding protein-like domain
COCFCCGP_00743 5.79e-214 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
COCFCCGP_00744 3.4e-229 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
COCFCCGP_00745 4.38e-161 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 LrgB-like family
COCFCCGP_00746 3.69e-87 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 LrgA family
COCFCCGP_00747 8.31e-169 lytT - - K ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator receiver
COCFCCGP_00748 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 LytS YhcK-type transmembrane receptor domain protein
COCFCCGP_00749 6.29e-191 - - - O - - - Band 7 protein
COCFCCGP_00750 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
COCFCCGP_00751 2.62e-200 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
COCFCCGP_00752 5.83e-51 - - - S - - - Cytochrome B5
COCFCCGP_00753 6.85e-146 nreC - - K ko:K07696 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 PFAM regulatory protein LuxR
COCFCCGP_00754 6.68e-206 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
COCFCCGP_00755 1.18e-76 - - - S - - - Iron-sulfur cluster assembly protein
COCFCCGP_00756 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
COCFCCGP_00757 4.34e-104 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
COCFCCGP_00758 2.6e-298 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
COCFCCGP_00759 3.9e-304 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
COCFCCGP_00760 2.21e-184 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
COCFCCGP_00761 9.89e-43 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain
COCFCCGP_00762 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
COCFCCGP_00763 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
COCFCCGP_00764 4.03e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
COCFCCGP_00765 1.3e-82 yuxO - - Q - - - Thioesterase superfamily
COCFCCGP_00766 2.88e-141 yvrI - - K ko:K03091,ko:K03093 - ko00000,ko03021 sigma factor activity
COCFCCGP_00767 2.07e-263 - - - G - - - Transporter, major facilitator family protein
COCFCCGP_00768 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
COCFCCGP_00769 2.02e-143 - - - T ko:K10716 - ko00000,ko02000 Ion transport 2 domain protein
COCFCCGP_00770 2.72e-102 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
COCFCCGP_00771 1.59e-287 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
COCFCCGP_00772 4.81e-124 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
COCFCCGP_00773 5.59e-249 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
COCFCCGP_00774 1.98e-232 rihA - - F ko:K01250 - ko00000,ko01000 Inosine-uridine preferring nucleoside hydrolase
COCFCCGP_00775 1.24e-65 - - - - - - - -
COCFCCGP_00776 7.58e-270 - - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
COCFCCGP_00777 4.85e-167 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
COCFCCGP_00778 4.09e-200 hlyD3 - - M ko:K02005 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
COCFCCGP_00779 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
COCFCCGP_00780 3.39e-186 - 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
COCFCCGP_00781 2.41e-189 - - - E - - - Glyoxalase-like domain
COCFCCGP_00782 6.23e-288 dhaT 1.1.1.202 - C ko:K00086 ko00561,ko00640,map00561,map00640 ko00000,ko00001,ko01000 Dehydrogenase
COCFCCGP_00783 1.1e-125 - - - S - - - reductase
COCFCCGP_00785 7.54e-115 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
COCFCCGP_00786 1.81e-226 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
COCFCCGP_00787 5.79e-117 pgpA - - I - - - Phosphatidylglycerophosphatase A
COCFCCGP_00788 1.17e-287 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
COCFCCGP_00789 2.52e-196 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
COCFCCGP_00790 4.13e-192 yycI - - S - - - YycH protein
COCFCCGP_00791 2.41e-315 yycH - - S - - - YycH protein
COCFCCGP_00792 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
COCFCCGP_00793 3.69e-168 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
COCFCCGP_00795 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
COCFCCGP_00796 6.55e-97 - - - K ko:K18909 - ko00000,ko00002,ko01504,ko03000 helix_turn_helix multiple antibiotic resistance protein
COCFCCGP_00798 1.95e-273 - - - L - - - Integrase core domain
COCFCCGP_00799 2.98e-163 - - - O - - - Bacterial dnaA protein
COCFCCGP_00800 3.44e-12 - - - K - - - DNA-binding helix-turn-helix protein
COCFCCGP_00801 1.86e-210 - - - S - - - Polyphosphate nucleotide phosphotransferase, PPK2 family
COCFCCGP_00802 3.85e-72 - - - - - - - -
COCFCCGP_00803 3.09e-268 yttB - - EGP - - - Major Facilitator
COCFCCGP_00804 6.04e-307 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
COCFCCGP_00805 1.25e-97 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
COCFCCGP_00806 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
COCFCCGP_00807 9.36e-48 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
COCFCCGP_00808 5.93e-114 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
COCFCCGP_00809 4.55e-64 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
COCFCCGP_00810 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
COCFCCGP_00811 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
COCFCCGP_00812 1.7e-261 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
COCFCCGP_00813 5.41e-47 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
COCFCCGP_00814 9.78e-14 dhrS4 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Oxidoreductase, short chain dehydrogenase reductase family protein
COCFCCGP_00815 1.13e-104 dhrS4 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Oxidoreductase, short chain dehydrogenase reductase family protein
COCFCCGP_00816 1.41e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
COCFCCGP_00817 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
COCFCCGP_00818 7.96e-21 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
COCFCCGP_00819 1.39e-76 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
COCFCCGP_00820 2.96e-172 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
COCFCCGP_00821 3.96e-222 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
COCFCCGP_00822 1.61e-292 - - - - - - - -
COCFCCGP_00823 1.21e-266 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
COCFCCGP_00824 5.39e-184 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
COCFCCGP_00825 2.49e-187 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
COCFCCGP_00826 1.25e-262 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
COCFCCGP_00827 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
COCFCCGP_00828 8.65e-226 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
COCFCCGP_00829 0.0 atp2C1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
COCFCCGP_00830 4.16e-112 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
COCFCCGP_00831 0.0 yagE - - E - - - amino acid
COCFCCGP_00832 9.45e-152 - - - S - - - HAD hydrolase, family IA, variant
COCFCCGP_00833 1.86e-62 - - - S - - - PD-(D/E)XK nuclease family transposase
COCFCCGP_00834 1.33e-162 - - - L - - - Helix-turn-helix domain
COCFCCGP_00835 2.89e-193 - - - L ko:K07497 - ko00000 hmm pf00665
COCFCCGP_00836 3.42e-233 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
COCFCCGP_00837 5.46e-233 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
COCFCCGP_00838 7.72e-178 - - - IQ - - - KR domain
COCFCCGP_00839 1.47e-171 - - - S ko:K07090 - ko00000 membrane transporter protein
COCFCCGP_00840 1.22e-126 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
COCFCCGP_00841 3.98e-315 - - - S ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
COCFCCGP_00842 4.83e-146 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
COCFCCGP_00843 6.5e-71 - - - - - - - -
COCFCCGP_00844 0.0 nhaK - - P ko:K03316 - ko00000 Sodium proton antiporter
COCFCCGP_00845 6.35e-69 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
COCFCCGP_00846 2.53e-241 ybcH - - D ko:K06889 - ko00000 Alpha beta
COCFCCGP_00847 1.3e-95 - - - K - - - Transcriptional regulator
COCFCCGP_00848 3.46e-207 - - - - - - - -
COCFCCGP_00849 9.77e-231 - - - C - - - Zinc-binding dehydrogenase
COCFCCGP_00850 0.0 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system Galactitol-specific IIC component
COCFCCGP_00851 6.79e-271 - - - EGP - - - Major Facilitator
COCFCCGP_00852 3.18e-11 - - - - - - - -
COCFCCGP_00853 1.78e-83 - - - - - - - -
COCFCCGP_00854 1.42e-248 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
COCFCCGP_00855 3.04e-105 uspA3 - - T - - - universal stress protein
COCFCCGP_00856 0.0 fusA1 - - J - - - elongation factor G
COCFCCGP_00857 2.17e-213 - - - GK - - - ROK family
COCFCCGP_00858 1.39e-310 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
COCFCCGP_00859 0.0 - - - G - - - Right handed beta helix region
COCFCCGP_00860 0.0 - - - G ko:K03292 - ko00000 MFS/sugar transport protein
COCFCCGP_00861 1.81e-222 rhaS2 - - K - - - Transcriptional regulator, AraC family
COCFCCGP_00862 0.0 xylT - - EGP - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
COCFCCGP_00864 1.75e-275 xylR - - GK - - - ROK family
COCFCCGP_00865 2.49e-39 - - - - - - - -
COCFCCGP_00866 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
COCFCCGP_00867 1.77e-137 maa3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
COCFCCGP_00868 1.57e-199 - - - U ko:K05340 - ko00000,ko02000 sugar transport
COCFCCGP_00869 0.0 yclK - - T - - - Histidine kinase
COCFCCGP_00870 2.7e-172 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
COCFCCGP_00872 2.2e-110 lytE - - M - - - Lysin motif
COCFCCGP_00873 9.84e-194 - - - S - - - Cof-like hydrolase
COCFCCGP_00874 3.7e-106 - - - K - - - Transcriptional regulator
COCFCCGP_00875 0.0 oatA - - I - - - Acyltransferase
COCFCCGP_00876 5.17e-70 - - - - - - - -
COCFCCGP_00877 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
COCFCCGP_00878 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
COCFCCGP_00879 7.48e-165 ybbR - - S - - - YbbR-like protein
COCFCCGP_00880 6.61e-195 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
COCFCCGP_00881 0.0 fucP - - G ko:K02429 - ko00000,ko02000 Major Facilitator Superfamily
COCFCCGP_00882 1.43e-87 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
COCFCCGP_00883 1.31e-213 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
COCFCCGP_00884 1.12e-214 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
COCFCCGP_00885 3.7e-133 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
COCFCCGP_00886 3.55e-99 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
COCFCCGP_00887 1.46e-112 - - - K - - - Acetyltransferase (GNAT) domain
COCFCCGP_00888 6.95e-105 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
COCFCCGP_00889 1.38e-228 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
COCFCCGP_00890 1.84e-174 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
COCFCCGP_00891 9.61e-137 - - - - - - - -
COCFCCGP_00892 3.15e-108 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
COCFCCGP_00893 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
COCFCCGP_00894 3.29e-187 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Serine aminopeptidase, S33
COCFCCGP_00895 1.43e-47 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
COCFCCGP_00896 0.0 eriC - - P ko:K03281 - ko00000 chloride
COCFCCGP_00897 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
COCFCCGP_00898 2.29e-276 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
COCFCCGP_00899 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
COCFCCGP_00900 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
COCFCCGP_00901 1.51e-131 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
COCFCCGP_00902 2.86e-244 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
COCFCCGP_00903 1.02e-240 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
COCFCCGP_00904 1.52e-61 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
COCFCCGP_00905 6.15e-234 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
COCFCCGP_00906 0.0 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
COCFCCGP_00907 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
COCFCCGP_00908 8.03e-58 yrzL - - S - - - Belongs to the UPF0297 family
COCFCCGP_00909 3.62e-100 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
COCFCCGP_00910 3.75e-63 yrzB - - S - - - Belongs to the UPF0473 family
COCFCCGP_00911 2.4e-120 cvpA - - S - - - Colicin V production protein
COCFCCGP_00912 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
COCFCCGP_00913 2.86e-72 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
COCFCCGP_00914 1.01e-124 yslB - - S - - - Protein of unknown function (DUF2507)
COCFCCGP_00915 2.58e-184 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
COCFCCGP_00916 3.33e-133 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
COCFCCGP_00917 5.68e-121 - - - S ko:K07095 - ko00000 Phosphoesterase
COCFCCGP_00918 3.62e-100 ykuL - - S - - - (CBS) domain
COCFCCGP_00919 1.1e-195 - - - S - - - haloacid dehalogenase-like hydrolase
COCFCCGP_00920 6.23e-188 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
COCFCCGP_00921 8.88e-71 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
COCFCCGP_00922 1.84e-75 - - - - - - - -
COCFCCGP_00923 4.4e-269 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
COCFCCGP_00924 3.28e-233 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
COCFCCGP_00925 1.15e-178 - - - - - - - -
COCFCCGP_00926 1.22e-168 yebC - - K - - - Transcriptional regulatory protein
COCFCCGP_00927 4.67e-232 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
COCFCCGP_00928 2.49e-232 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
COCFCCGP_00929 6.31e-62 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
COCFCCGP_00930 1.01e-100 - - - NU ko:K02246 - ko00000,ko00002,ko02044 general secretion pathway protein
COCFCCGP_00931 1.61e-54 - - - - - - - -
COCFCCGP_00932 9.32e-92 - - - - ko:K02248 - ko00000,ko00002,ko02044 -
COCFCCGP_00934 2.07e-185 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
COCFCCGP_00935 4.18e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
COCFCCGP_00936 1.08e-146 - - - S - - - Calcineurin-like phosphoesterase
COCFCCGP_00937 9.28e-121 yutD - - S - - - Protein of unknown function (DUF1027)
COCFCCGP_00938 2.87e-171 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
COCFCCGP_00939 1.03e-135 - - - S - - - Protein of unknown function (DUF1461)
COCFCCGP_00940 1.83e-149 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
COCFCCGP_00941 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
COCFCCGP_00942 7.25e-97 - - - F - - - Nudix hydrolase
COCFCCGP_00943 2.75e-132 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
COCFCCGP_00944 1.27e-108 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
COCFCCGP_00945 6.02e-34 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
COCFCCGP_00946 4.65e-193 - - - - - - - -
COCFCCGP_00947 8.65e-53 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain protein
COCFCCGP_00948 2.14e-123 - - - K - - - Transcriptional regulator (TetR family)
COCFCCGP_00949 0.0 yhgE - - V ko:K01421 - ko00000 domain protein
COCFCCGP_00950 9.09e-233 - 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COCFCCGP_00951 6.08e-13 - - - S - - - CsbD-like
COCFCCGP_00952 1.34e-47 - - - S - - - Transglycosylase associated protein
COCFCCGP_00953 1.27e-291 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
COCFCCGP_00954 9.5e-162 pgm3 - - G - - - phosphoglycerate mutase
COCFCCGP_00955 4.66e-148 - - - S ko:K03975 - ko00000 SNARE associated Golgi protein
COCFCCGP_00956 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
COCFCCGP_00957 1.26e-44 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
COCFCCGP_00958 1.77e-202 - - - EG - - - EamA-like transporter family
COCFCCGP_00959 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
COCFCCGP_00960 3.39e-225 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
COCFCCGP_00961 7.02e-288 - - - S ko:K07133 - ko00000 cog cog1373
COCFCCGP_00963 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
COCFCCGP_00964 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
COCFCCGP_00965 7.8e-41 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
COCFCCGP_00966 2.18e-55 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
COCFCCGP_00967 3.1e-153 - - - L - - - Belongs to the 'phage' integrase family
COCFCCGP_00968 1.88e-131 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
COCFCCGP_00969 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
COCFCCGP_00972 2.17e-77 - - - - - - - -
COCFCCGP_00973 5.52e-107 - - - L - - - Phage integrase SAM-like domain
COCFCCGP_00975 1.88e-251 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
COCFCCGP_00976 8.5e-208 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
COCFCCGP_00977 1.53e-123 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
COCFCCGP_00978 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
COCFCCGP_00979 4.47e-16 - - - S - - - Protein of unknown function (DUF4044)
COCFCCGP_00980 7.76e-74 - - - - - - - -
COCFCCGP_00981 1.5e-101 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
COCFCCGP_00982 9.31e-224 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
COCFCCGP_00983 3.47e-73 ftsL - - D - - - Cell division protein FtsL
COCFCCGP_00984 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
COCFCCGP_00985 7.73e-230 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
COCFCCGP_00986 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
COCFCCGP_00987 1.45e-260 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
COCFCCGP_00988 3.54e-194 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
COCFCCGP_00989 0.0 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
COCFCCGP_00990 6.52e-289 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
COCFCCGP_00991 1.11e-92 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
COCFCCGP_00992 3.2e-54 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
COCFCCGP_00993 1.97e-185 ylmH - - S - - - S4 domain protein
COCFCCGP_00994 3.71e-109 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
COCFCCGP_00995 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
COCFCCGP_00996 5.69e-44 cspB - - K ko:K03704 - ko00000,ko03000 Cold shock protein
COCFCCGP_00997 2.48e-129 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
COCFCCGP_00998 1.54e-33 - - - - - - - -
COCFCCGP_00999 3.4e-162 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
COCFCCGP_01000 1.75e-275 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
COCFCCGP_01001 1.13e-75 XK27_04120 - - S - - - Putative amino acid metabolism
COCFCCGP_01002 2.15e-286 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
COCFCCGP_01003 6.67e-158 pgm6 - - G - - - phosphoglycerate mutase
COCFCCGP_01004 3.82e-157 - - - S - - - repeat protein
COCFCCGP_01005 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
COCFCCGP_01006 8.58e-223 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
COCFCCGP_01007 5.09e-162 - - - M - - - ErfK YbiS YcfS YnhG
COCFCCGP_01009 1.93e-131 - - - - - - - -
COCFCCGP_01010 1.02e-279 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
COCFCCGP_01011 2.56e-188 - - - S - - - Alpha beta hydrolase
COCFCCGP_01012 2.84e-264 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 dehydrogenase
COCFCCGP_01013 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
COCFCCGP_01014 1.77e-56 - - - - - - - -
COCFCCGP_01015 3.18e-160 pgm3 - - G - - - phosphoglycerate mutase family
COCFCCGP_01016 1.22e-31 - - - S - - - C4-dicarboxylate anaerobic carrier
COCFCCGP_01017 9.8e-305 - - - S - - - C4-dicarboxylate anaerobic carrier
COCFCCGP_01018 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
COCFCCGP_01019 4.79e-307 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
COCFCCGP_01020 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
COCFCCGP_01021 0.0 - - - L - - - Transposase
COCFCCGP_01022 2.35e-215 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
COCFCCGP_01023 8.16e-212 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
COCFCCGP_01024 3.78e-169 yceF - - P ko:K05794 - ko00000 membrane
COCFCCGP_01025 4.38e-72 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
COCFCCGP_01026 7.25e-301 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
COCFCCGP_01027 1.39e-44 - - - M - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
COCFCCGP_01028 1.14e-74 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
COCFCCGP_01029 5.53e-119 - - - P - - - Cadmium resistance transporter
COCFCCGP_01030 5.63e-177 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
COCFCCGP_01031 5.58e-195 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
COCFCCGP_01032 3.16e-233 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
COCFCCGP_01033 7.06e-164 - - - M - - - PFAM NLP P60 protein
COCFCCGP_01034 4.92e-305 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
COCFCCGP_01035 6.06e-231 - - - - - - - -
COCFCCGP_01036 5.27e-169 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
COCFCCGP_01037 4.57e-307 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
COCFCCGP_01038 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
COCFCCGP_01039 8.26e-136 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
COCFCCGP_01040 1.54e-247 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
COCFCCGP_01041 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
COCFCCGP_01042 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
COCFCCGP_01043 1.15e-162 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
COCFCCGP_01044 2.23e-50 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
COCFCCGP_01045 8.68e-169 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
COCFCCGP_01046 0.0 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
COCFCCGP_01047 1.61e-271 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
COCFCCGP_01048 3.65e-109 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
COCFCCGP_01049 8.03e-169 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Belongs to the alpha-acetolactate decarboxylase family
COCFCCGP_01050 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
COCFCCGP_01051 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
COCFCCGP_01052 6.76e-227 ydbI - - K - - - AI-2E family transporter
COCFCCGP_01053 1.15e-301 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
COCFCCGP_01054 2.62e-122 ribB 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
COCFCCGP_01055 1.11e-149 - - - S - - - Haloacid dehalogenase-like hydrolase
COCFCCGP_01056 1.83e-148 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
COCFCCGP_01057 3.95e-167 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
COCFCCGP_01058 1.95e-220 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
COCFCCGP_01059 4.45e-315 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
COCFCCGP_01060 6.04e-220 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
COCFCCGP_01061 2.79e-179 - - - K - - - LysR substrate binding domain
COCFCCGP_01062 7.67e-252 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
COCFCCGP_01063 1.13e-289 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
COCFCCGP_01064 1.16e-133 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
COCFCCGP_01065 2.06e-197 - - - S - - - Helix-turn-helix domain
COCFCCGP_01066 0.0 ymfH - - S - - - Peptidase M16
COCFCCGP_01067 2.13e-294 ymfF - - S - - - Peptidase M16 inactive domain protein
COCFCCGP_01068 4.04e-205 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
COCFCCGP_01069 1.19e-150 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
COCFCCGP_01070 4.45e-141 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
COCFCCGP_01071 1.62e-118 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
COCFCCGP_01072 4.46e-194 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
COCFCCGP_01073 8.33e-230 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
COCFCCGP_01074 6.98e-156 radC - - L ko:K03630 - ko00000 DNA repair protein
COCFCCGP_01075 1.23e-311 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
COCFCCGP_01076 1.22e-292 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
COCFCCGP_01077 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
COCFCCGP_01078 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
COCFCCGP_01079 6.92e-236 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
COCFCCGP_01080 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
COCFCCGP_01081 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
COCFCCGP_01082 5.83e-292 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
COCFCCGP_01083 2.48e-274 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
COCFCCGP_01084 1.33e-312 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
COCFCCGP_01085 5.96e-139 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
COCFCCGP_01087 3.91e-40 - - - M - - - LPXTG-motif cell wall anchor domain protein
COCFCCGP_01088 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
COCFCCGP_01089 5.28e-225 - - - M - - - LPXTG-motif cell wall anchor domain protein
COCFCCGP_01090 0.0 - 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Thioredoxin domain
COCFCCGP_01091 6.57e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Peroxiredoxin
COCFCCGP_01092 5.11e-188 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
COCFCCGP_01093 5.26e-156 sdhB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
COCFCCGP_01096 2.48e-57 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
COCFCCGP_01097 9.61e-213 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
COCFCCGP_01098 2.11e-290 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
COCFCCGP_01099 1.24e-165 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
COCFCCGP_01100 9.02e-201 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
COCFCCGP_01101 1.81e-225 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
COCFCCGP_01102 0.0 lacZ 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
COCFCCGP_01103 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
COCFCCGP_01104 5.98e-242 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
COCFCCGP_01105 4.45e-109 - - - - - - - -
COCFCCGP_01106 2.17e-205 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
COCFCCGP_01107 5.86e-68 - - - S - - - Mazg nucleotide pyrophosphohydrolase
COCFCCGP_01108 1.28e-46 - - - - - - - -
COCFCCGP_01109 4.05e-70 - - - S - - - branched-chain amino acid
COCFCCGP_01110 4.95e-195 - - - E - - - AzlC protein
COCFCCGP_01111 5.47e-261 hpk31 - - T - - - Histidine kinase
COCFCCGP_01112 3.27e-159 vanR - - K - - - response regulator
COCFCCGP_01113 8.13e-263 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
COCFCCGP_01114 1.32e-219 deoR - - K ko:K05346 - ko00000,ko03000 sugar-binding domain protein
COCFCCGP_01115 3.27e-167 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
COCFCCGP_01116 2.15e-298 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 pyrimidine-nucleoside phosphorylase
COCFCCGP_01117 1.09e-296 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
COCFCCGP_01118 6.86e-154 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
COCFCCGP_01119 4.25e-173 - - - S - - - Protein of unknown function (DUF1129)
COCFCCGP_01120 6.1e-255 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
COCFCCGP_01121 5.8e-43 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
COCFCCGP_01122 4.83e-198 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
COCFCCGP_01123 2.79e-178 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
COCFCCGP_01124 3.73e-200 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
COCFCCGP_01125 6.29e-163 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
COCFCCGP_01126 5.97e-208 - 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 3-hydroxyacyl-CoA dehydrogenase
COCFCCGP_01127 2.76e-217 rihA 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
COCFCCGP_01128 3.42e-278 nupG - - F ko:K03317,ko:K11535,ko:K16323 - ko00000,ko02000 Nucleoside transporter
COCFCCGP_01129 1.77e-285 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
COCFCCGP_01130 5.67e-178 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
COCFCCGP_01131 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
COCFCCGP_01132 0.0 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
COCFCCGP_01133 0.0 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
COCFCCGP_01134 7.01e-109 - - - - - - - -
COCFCCGP_01135 8.23e-237 - 2.7.7.65 - T ko:K02488 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko00002,ko01000,ko02022 GGDEF domain
COCFCCGP_01136 6.11e-158 - - - T - - - Putative diguanylate phosphodiesterase
COCFCCGP_01137 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
COCFCCGP_01138 1.43e-252 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
COCFCCGP_01139 5.35e-121 - - - S - - - ECF transporter, substrate-specific component
COCFCCGP_01140 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
COCFCCGP_01141 7.17e-146 - - - GM - - - NAD dependent epimerase dehydratase family protein
COCFCCGP_01142 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
COCFCCGP_01143 7.6e-269 - - - EGP - - - Major Facilitator Superfamily
COCFCCGP_01144 1.61e-291 - - - - - - - -
COCFCCGP_01145 6.71e-102 - - - K - - - Transcriptional regulator, HxlR family
COCFCCGP_01146 3.2e-138 XK27_02070 - - S ko:K07078 - ko00000 Nitroreductase family
COCFCCGP_01147 2.74e-69 ydeP - - K - - - Transcriptional regulator, HxlR family
COCFCCGP_01148 7.48e-155 - - - GM - - - NmrA-like family
COCFCCGP_01149 5.36e-92 - - - S ko:K02348 - ko00000 Gnat family
COCFCCGP_01150 2.3e-52 - - - S - - - Cytochrome B5
COCFCCGP_01151 8.47e-08 - - - S - - - Cytochrome B5
COCFCCGP_01152 4.51e-54 - - - S - - - Cytochrome B5
COCFCCGP_01153 1.94e-269 - 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
COCFCCGP_01155 1.63e-233 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
COCFCCGP_01156 1.82e-316 - - - E ko:K03294 - ko00000 amino acid
COCFCCGP_01157 2.52e-270 npp - - S - - - type I phosphodiesterase nucleotide pyrophosphatase
COCFCCGP_01158 2.01e-13 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
COCFCCGP_01162 1.17e-90 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
COCFCCGP_01168 1.08e-16 - - - S - - - Antirestriction protein (ArdA)
COCFCCGP_01185 4.2e-15 - - - D - - - Antitoxin component of a toxin-antitoxin (TA) module
COCFCCGP_01186 6.84e-30 - - - S - - - YoeB-like toxin of bacterial type II toxin-antitoxin system
COCFCCGP_01187 1.02e-214 fruR3 - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
COCFCCGP_01188 5.24e-289 glpT - - G ko:K02445 - ko00000,ko02000 Major Facilitator Superfamily
COCFCCGP_01190 3.38e-54 - - - S ko:K07341 - ko00000,ko02048 Fic/DOC family
COCFCCGP_01194 2.86e-31 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
COCFCCGP_01195 3.81e-62 - - - - - - - -
COCFCCGP_01197 3.44e-47 - - - S - - - PD-(D/E)XK nuclease family transposase
COCFCCGP_01198 1.52e-205 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
COCFCCGP_01199 2.64e-315 - 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 pyridine nucleotide-disulfide oxidoreductase
COCFCCGP_01200 1.16e-114 XK27_07210 - - S - - - B3 4 domain
COCFCCGP_01201 8.65e-119 - - - - - - - -
COCFCCGP_01202 1.25e-157 pnb - - C - - - nitroreductase
COCFCCGP_01203 3.43e-96 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Methyltransferase
COCFCCGP_01204 1.93e-216 XK27_00915 - - C - - - Luciferase-like monooxygenase
COCFCCGP_01205 7.88e-215 - 3.2.1.96, 3.5.1.28 GH73 M ko:K01227,ko:K01447,ko:K13714,ko:K13731 ko00511,ko05100,map00511,map05100 ko00000,ko00001,ko01000 N-acetylmuramoyl-L-alanine amidase
COCFCCGP_01206 1.53e-97 - - - S - - - Protein of unknown function (DUF3021)
COCFCCGP_01207 1.05e-102 - - - K - - - LytTr DNA-binding domain
COCFCCGP_01208 1.2e-118 - - - K - - - Acetyltransferase (GNAT) family
COCFCCGP_01209 5.18e-27 - - - - - - - -
COCFCCGP_01210 2.64e-152 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
COCFCCGP_01211 2.25e-105 yjcF 3.5.4.33, 4.4.1.8 - K ko:K02348,ko:K07000,ko:K11991,ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007,ko03016 protein acetylation
COCFCCGP_01212 2.87e-250 - - - S - - - Protein of unknown function (DUF3114)
COCFCCGP_01213 0.0 gshA 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
COCFCCGP_01214 1.86e-213 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
COCFCCGP_01215 1.25e-136 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
COCFCCGP_01216 5.4e-80 - - - S - - - Domain of unknown function (DUF4828)
COCFCCGP_01217 5.34e-245 mocA - - S - - - Oxidoreductase
COCFCCGP_01218 3.81e-291 yfmL - - L - - - DEAD DEAH box helicase
COCFCCGP_01220 2.09e-266 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
COCFCCGP_01221 2.02e-72 - - - - - - - -
COCFCCGP_01222 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
COCFCCGP_01223 1.25e-78 - - - - - - - -
COCFCCGP_01224 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
COCFCCGP_01225 7.01e-244 - - - E - - - Zinc-binding dehydrogenase
COCFCCGP_01226 2.72e-113 - - - K - - - transcriptional regulator (TetR family)
COCFCCGP_01227 2.39e-234 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
COCFCCGP_01228 4.22e-148 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
COCFCCGP_01229 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
COCFCCGP_01230 1.18e-50 - - - - - - - -
COCFCCGP_01231 4.57e-65 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
COCFCCGP_01232 1.7e-267 - 3.2.1.17 CBM50 NU ko:K01185,ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
COCFCCGP_01233 3.11e-220 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
COCFCCGP_01234 2.14e-32 - - - - - - - -
COCFCCGP_01235 1.03e-146 - - - - - - - -
COCFCCGP_01236 4.99e-273 yttB - - EGP - - - Major Facilitator
COCFCCGP_01237 6.55e-310 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
COCFCCGP_01238 2.46e-113 - - - - - - - -
COCFCCGP_01239 4.3e-142 nnrE 5.1.99.6 - H ko:K17759 - ko00000,ko01000 Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
COCFCCGP_01240 0.0 - - - S - - - Putative peptidoglycan binding domain
COCFCCGP_01241 0.0 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
COCFCCGP_01243 0.0 - - - L - - - Helicase C-terminal domain protein
COCFCCGP_01244 2.72e-102 - 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 PAP2 superfamily
COCFCCGP_01245 4.45e-226 ydhF - - S - - - Aldo keto reductase
COCFCCGP_01247 8.69e-182 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
COCFCCGP_01248 7.3e-82 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
COCFCCGP_01249 1.24e-132 - - - S ko:K07002 - ko00000 Serine hydrolase
COCFCCGP_01251 6.58e-231 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
COCFCCGP_01252 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
COCFCCGP_01253 2.3e-52 - - - S - - - Cytochrome b5-like Heme/Steroid binding domain
COCFCCGP_01254 1.63e-148 - - - S ko:K07118 - ko00000 NAD(P)H-binding
COCFCCGP_01255 3.88e-50 - - - - - - - -
COCFCCGP_01256 3e-168 - - - IQ - - - dehydrogenase reductase
COCFCCGP_01257 1.67e-306 - - - EGP - - - MFS transporter, metabolite H symporter (MHS) family protein
COCFCCGP_01258 8.85e-147 - - - L - - - Belongs to the 'phage' integrase family
COCFCCGP_01263 4.74e-213 - - - H - - - geranyltranstransferase activity
COCFCCGP_01264 9.46e-235 - - - - - - - -
COCFCCGP_01265 3.11e-26 - - - - - - - -
COCFCCGP_01266 7.45e-150 nreC - - K ko:K07696 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 PFAM regulatory protein LuxR
COCFCCGP_01267 9.18e-243 nreB 2.7.13.3 - F ko:K07683 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Sensor histidine kinase
COCFCCGP_01268 1.56e-60 - - - - - - - -
COCFCCGP_01269 1.17e-135 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
COCFCCGP_01270 9.66e-110 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
COCFCCGP_01271 2.19e-291 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 MoeA N-terminal region (domain I and II)
COCFCCGP_01272 2.86e-108 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
COCFCCGP_01273 2.33e-239 moeB 2.7.7.80 - H ko:K21029 ko04122,map04122 ko00000,ko00001,ko01000 ThiF family
COCFCCGP_01274 0.0 narZ 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
COCFCCGP_01275 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
COCFCCGP_01276 7.3e-131 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase molybdenum cofactor assembly chaperone
COCFCCGP_01277 9.45e-168 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase
COCFCCGP_01278 2.82e-299 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
COCFCCGP_01279 7.66e-196 - - - EG - - - EamA-like transporter family
COCFCCGP_01280 1.15e-152 - - - L - - - Integrase
COCFCCGP_01281 7.24e-204 rssA - - S - - - Phospholipase, patatin family
COCFCCGP_01282 0.0 malT - - G ko:K16211 - ko00000,ko02000 Major Facilitator
COCFCCGP_01283 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
COCFCCGP_01284 1.76e-154 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
COCFCCGP_01285 1.76e-112 - - - T - - - Region found in RelA / SpoT proteins
COCFCCGP_01286 3.15e-153 dltr - - K - - - response regulator
COCFCCGP_01287 1.13e-289 sptS - - T - - - Histidine kinase
COCFCCGP_01288 1.41e-265 - - - P - - - Voltage gated chloride channel
COCFCCGP_01289 0.0 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
COCFCCGP_01290 1.76e-174 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
COCFCCGP_01291 2.1e-214 - - - C - - - Aldo keto reductase
COCFCCGP_01292 1.86e-63 - - - S - - - Cupin 2, conserved barrel domain protein
COCFCCGP_01293 0.0 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
COCFCCGP_01294 7.6e-113 - - - S - - - ECF-type riboflavin transporter, S component
COCFCCGP_01295 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
COCFCCGP_01296 3.7e-233 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
COCFCCGP_01297 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
COCFCCGP_01298 2.29e-117 - - - - - - - -
COCFCCGP_01299 4.65e-123 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
COCFCCGP_01302 4.59e-248 - - - M - - - transferase activity, transferring glycosyl groups
COCFCCGP_01303 6.21e-266 secY2 - - U - - - Part of the accessory SecA2 SecY2 system specifically required for export of
COCFCCGP_01304 0.0 - - - M - - - transferase activity, transferring glycosyl groups
COCFCCGP_01305 0.0 asp2 - - S ko:K12269 - ko00000,ko02044 Accessory Sec system GspB-transporter
COCFCCGP_01306 9.55e-210 asp3 - - S ko:K12270 - ko00000,ko02044 Accessory Sec secretory system ASP3
COCFCCGP_01307 0.0 secA2 - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
COCFCCGP_01308 0.0 gtf1 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
COCFCCGP_01309 0.0 gtf2 - - M - - - A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
COCFCCGP_01311 1.9e-75 - - - M - - - family 8
COCFCCGP_01312 0.0 - - - M - - - family 8
COCFCCGP_01313 0.0 - - - M - - - family 8
COCFCCGP_01316 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
COCFCCGP_01317 2.06e-108 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
COCFCCGP_01318 2.51e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
COCFCCGP_01319 1.14e-152 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
COCFCCGP_01320 1.15e-263 - - - - - - - -
COCFCCGP_01321 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
COCFCCGP_01322 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
COCFCCGP_01323 4.92e-142 - - - K - - - Bacterial regulatory proteins, tetR family
COCFCCGP_01324 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
COCFCCGP_01325 1.39e-101 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
COCFCCGP_01326 8.94e-250 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
COCFCCGP_01327 8.57e-20 - - - S ko:K06889 - ko00000 Hydrolases of the alpha beta superfamily
COCFCCGP_01328 2.07e-167 - - - S ko:K06889 - ko00000 Hydrolases of the alpha beta superfamily
COCFCCGP_01329 1.28e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
COCFCCGP_01330 5.45e-153 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
COCFCCGP_01331 6.64e-139 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
COCFCCGP_01332 3.61e-61 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
COCFCCGP_01333 1.16e-203 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
COCFCCGP_01334 5.72e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
COCFCCGP_01335 8.8e-70 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
COCFCCGP_01336 9.81e-157 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
COCFCCGP_01337 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
COCFCCGP_01338 5.49e-38 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
COCFCCGP_01339 1.1e-55 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
COCFCCGP_01340 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
COCFCCGP_01341 2.58e-65 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
COCFCCGP_01342 7.42e-125 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
COCFCCGP_01343 4.97e-40 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
COCFCCGP_01344 1.54e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
COCFCCGP_01345 2.6e-124 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
COCFCCGP_01346 5.03e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
COCFCCGP_01347 1.2e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
COCFCCGP_01348 5.94e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
COCFCCGP_01349 6.05e-93 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
COCFCCGP_01350 2.88e-306 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
COCFCCGP_01351 4.52e-161 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
COCFCCGP_01352 9.82e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
COCFCCGP_01353 5.79e-21 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
COCFCCGP_01354 1.54e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
COCFCCGP_01355 1.62e-83 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
COCFCCGP_01356 8.91e-220 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
COCFCCGP_01357 8.08e-83 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
COCFCCGP_01358 1.23e-186 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
COCFCCGP_01359 9.73e-195 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
COCFCCGP_01360 1.43e-181 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
COCFCCGP_01361 6.12e-182 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
COCFCCGP_01362 9.25e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
COCFCCGP_01363 3.94e-85 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
COCFCCGP_01364 5.14e-217 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
COCFCCGP_01365 2.06e-198 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
COCFCCGP_01366 2e-243 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
COCFCCGP_01367 5.25e-140 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
COCFCCGP_01368 1.96e-275 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
COCFCCGP_01369 0.0 eriC - - P ko:K03281 - ko00000 chloride
COCFCCGP_01370 3.53e-100 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
COCFCCGP_01371 1.96e-138 - - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, permease protein
COCFCCGP_01372 1.01e-180 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
COCFCCGP_01373 2.35e-139 proWZ - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
COCFCCGP_01374 1.77e-207 proWY - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, QAT family
COCFCCGP_01375 3.87e-97 ywnA - - K - - - Transcriptional regulator
COCFCCGP_01376 1.83e-197 - - - GM - - - NAD(P)H-binding
COCFCCGP_01377 4.44e-11 - - - - - - - -
COCFCCGP_01378 5.23e-276 - 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Metalloenzyme superfamily
COCFCCGP_01379 0.0 cadA - - P - - - P-type ATPase
COCFCCGP_01380 1.31e-161 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
COCFCCGP_01381 7.41e-163 - - - - - - - -
COCFCCGP_01383 7.63e-117 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
COCFCCGP_01384 2.71e-81 asp1 - - S - - - Asp23 family, cell envelope-related function
COCFCCGP_01385 3.09e-35 - - - - - - - -
COCFCCGP_01386 1.14e-124 - - - - - - - -
COCFCCGP_01387 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
COCFCCGP_01388 3.28e-232 - - - K ko:K02525 - ko00000,ko03000 Transcriptional regulator, LacI family
COCFCCGP_01389 2.2e-192 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
COCFCCGP_01390 3.09e-87 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
COCFCCGP_01391 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
COCFCCGP_01392 5.91e-125 - - - K - - - Acetyltransferase (GNAT) domain
COCFCCGP_01393 2.2e-62 - - - - - - - -
COCFCCGP_01394 1.28e-41 - - - - - - - -
COCFCCGP_01395 1.26e-60 - - - - - - - -
COCFCCGP_01396 1.47e-100 - - - S - - - Protein of unknown function (DUF805)
COCFCCGP_01397 6.04e-178 butA 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 reductase
COCFCCGP_01398 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
COCFCCGP_01399 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
COCFCCGP_01400 4.37e-39 - - - - - - - -
COCFCCGP_01401 3.3e-265 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
COCFCCGP_01403 5.28e-76 - - - - - - - -
COCFCCGP_01404 7.55e-265 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
COCFCCGP_01405 6.63e-281 yojA - - EG ko:K03299 - ko00000,ko02000 GntP family permease
COCFCCGP_01406 5.77e-104 - - - KT ko:K02647 - ko00000,ko03000 Putative sugar diacid recognition
COCFCCGP_01407 2.58e-254 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
COCFCCGP_01408 1.62e-276 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
COCFCCGP_01409 1.43e-177 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
COCFCCGP_01410 9.32e-223 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
COCFCCGP_01411 1.64e-283 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
COCFCCGP_01412 2.66e-111 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
COCFCCGP_01413 5.89e-314 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
COCFCCGP_01414 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
COCFCCGP_01415 3.17e-219 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
COCFCCGP_01416 7.08e-168 - - - M - - - transferase activity, transferring glycosyl groups
COCFCCGP_01417 5.68e-190 - - GT4 M ko:K02840 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 Glycosyl transferases group 1
COCFCCGP_01418 6.68e-302 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
COCFCCGP_01419 2.78e-275 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
COCFCCGP_01420 1.15e-152 - - - M - - - Bacterial sugar transferase
COCFCCGP_01421 1.38e-225 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
COCFCCGP_01422 1.84e-187 cps1D - - M - - - Domain of unknown function (DUF4422)
COCFCCGP_01423 2.02e-175 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
COCFCCGP_01424 2.53e-42 - - - - - - - -
COCFCCGP_01425 1.26e-46 - - - S - - - Protein of unknown function (DUF2922)
COCFCCGP_01426 7.47e-203 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
COCFCCGP_01427 0.0 potE - - E - - - Amino Acid
COCFCCGP_01428 0.0 arcD - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
COCFCCGP_01429 3.98e-280 arcT - - E - - - Aminotransferase
COCFCCGP_01430 1e-215 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
COCFCCGP_01431 4.7e-103 ykuP - - C ko:K03839 - ko00000 Flavodoxin
COCFCCGP_01432 4.94e-88 gtcA - - S - - - Teichoic acid glycosylation protein
COCFCCGP_01434 8.9e-317 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
COCFCCGP_01435 3.62e-217 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
COCFCCGP_01436 9.76e-93 - - - O - - - Preprotein translocase subunit SecB
COCFCCGP_01438 9.65e-40 - - - - - - - -
COCFCCGP_01439 6.17e-22 - - - - - - - -
COCFCCGP_01440 3e-39 - - - S - - - Protein of unknown function (DUF4065)
COCFCCGP_01443 1.29e-09 - - - - - - - -
COCFCCGP_01445 1.41e-199 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
COCFCCGP_01446 9.46e-263 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
COCFCCGP_01447 1.08e-137 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
COCFCCGP_01448 3.72e-204 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
COCFCCGP_01449 1.06e-134 - - - S - - - Polysaccharide biosynthesis protein
COCFCCGP_01450 1.87e-33 - - - M - - - Glycosyltransferase like family 2
COCFCCGP_01451 5.59e-58 - - - M - - - Glycosyltransferase, group 2 family protein
COCFCCGP_01452 7.43e-45 - - - S - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
COCFCCGP_01453 0.0 pepD3 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
COCFCCGP_01454 1.01e-254 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
COCFCCGP_01456 4.78e-222 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
COCFCCGP_01458 1.32e-74 - - - - - - - -
COCFCCGP_01459 4.65e-229 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
COCFCCGP_01460 3.36e-165 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
COCFCCGP_01461 4.8e-72 - - - - - - - -
COCFCCGP_01462 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
COCFCCGP_01463 1.88e-101 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
COCFCCGP_01464 1.26e-212 - - - G - - - Phosphotransferase enzyme family
COCFCCGP_01465 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
COCFCCGP_01466 6.06e-168 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
COCFCCGP_01467 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
COCFCCGP_01468 8.25e-31 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
COCFCCGP_01469 2.34e-92 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
COCFCCGP_01470 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
COCFCCGP_01471 1.06e-53 - - - - - - - -
COCFCCGP_01472 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
COCFCCGP_01473 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
COCFCCGP_01474 4.87e-242 yycB - - P ko:K03449 - ko00000,ko02000 Transporter, major facilitator family protein
COCFCCGP_01475 3.68e-97 - - - S ko:K04750 - ko00000 3-demethylubiquinone-9 3-methyltransferase
COCFCCGP_01476 1.98e-110 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
COCFCCGP_01477 1.67e-307 yhdP - - S - - - Transporter associated domain
COCFCCGP_01478 1.39e-198 - - - V - - - (ABC) transporter
COCFCCGP_01479 1.29e-113 - - - GM - - - epimerase
COCFCCGP_01480 5.25e-118 - - - K - - - Domain of unknown function (DUF1836)
COCFCCGP_01481 8.16e-103 yybA - - K - - - Transcriptional regulator
COCFCCGP_01482 7.74e-173 XK27_07210 - - S - - - B3 4 domain
COCFCCGP_01483 3.78e-236 XK27_12525 - - S - - - AI-2E family transporter
COCFCCGP_01484 1.92e-202 - - - G - - - Xylose isomerase domain protein TIM barrel
COCFCCGP_01485 1.51e-207 - - - - - - - -
COCFCCGP_01487 1.12e-135 - - - K - - - PFAM GCN5-related N-acetyltransferase
COCFCCGP_01488 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
COCFCCGP_01489 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
COCFCCGP_01490 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
COCFCCGP_01491 5.18e-222 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
COCFCCGP_01492 6.04e-271 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
COCFCCGP_01493 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
COCFCCGP_01494 1.72e-251 - - - EGP - - - Major Facilitator
COCFCCGP_01495 2.18e-115 ymdB - - S - - - Macro domain protein
COCFCCGP_01496 2.13e-142 - - - K - - - Helix-turn-helix domain
COCFCCGP_01497 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
COCFCCGP_01498 4.95e-63 - - - - - - - -
COCFCCGP_01499 1.32e-307 - - - S - - - Putative metallopeptidase domain
COCFCCGP_01500 1.46e-261 - - - S - - - associated with various cellular activities
COCFCCGP_01501 1.92e-153 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
COCFCCGP_01502 3.47e-85 yeaO - - S - - - Protein of unknown function, DUF488
COCFCCGP_01504 6.8e-151 yrkL - - S - - - Flavodoxin-like fold
COCFCCGP_01505 2.84e-73 - - - - - - - -
COCFCCGP_01507 1.97e-131 - - - S - - - PD-(D/E)XK nuclease family transposase
COCFCCGP_01508 1.62e-34 - - - S - - - PD-(D/E)XK nuclease family transposase
COCFCCGP_01509 5.87e-65 - - - - - - - -
COCFCCGP_01511 5.28e-262 yngD - - S ko:K07097 - ko00000 DHHA1 domain
COCFCCGP_01512 6.29e-165 - 1.1.1.100, 1.1.1.69 - I ko:K00046,ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
COCFCCGP_01513 2.08e-213 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
COCFCCGP_01514 3.47e-123 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
COCFCCGP_01515 2.95e-201 yvgN - - S - - - Aldo keto reductase
COCFCCGP_01516 1.07e-264 araR - - K ko:K02103 - ko00000,ko03000 Transcriptional regulator
COCFCCGP_01517 1.95e-109 uspA - - T - - - universal stress protein
COCFCCGP_01518 3.61e-61 - - - - - - - -
COCFCCGP_01519 1.88e-309 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
COCFCCGP_01520 2.03e-111 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
COCFCCGP_01521 9.79e-29 - - - - - - - -
COCFCCGP_01522 2e-98 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase
COCFCCGP_01523 2.98e-96 - - - S - - - Membrane
COCFCCGP_01524 1.35e-62 - - - S - - - Membrane
COCFCCGP_01525 8.18e-174 - - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
COCFCCGP_01526 0.0 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
COCFCCGP_01527 0.0 frc 2.8.3.16 - C ko:K07749 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
COCFCCGP_01528 2.56e-300 pbuG - - S ko:K06901 - ko00000,ko02000 permease
COCFCCGP_01529 4.46e-180 budC 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 reductase
COCFCCGP_01530 3.07e-149 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
COCFCCGP_01531 1.12e-129 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
COCFCCGP_01532 8.91e-270 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
COCFCCGP_01533 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
COCFCCGP_01534 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
COCFCCGP_01535 1.11e-260 camS - - S - - - sex pheromone
COCFCCGP_01536 3.22e-65 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
COCFCCGP_01537 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
COCFCCGP_01538 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
COCFCCGP_01539 1.69e-235 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
COCFCCGP_01540 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
COCFCCGP_01541 1.66e-123 - - - L - - - Integrase
COCFCCGP_01542 1.1e-211 - - - S - - - Protein of unknown function DUF262
COCFCCGP_01544 1.36e-214 ybhF_1 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
COCFCCGP_01545 0.0 - - - M ko:K01992 - ko00000,ko00002,ko02000 Exporter of polyketide antibiotics
COCFCCGP_01546 6.92e-148 - - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
COCFCCGP_01547 1.85e-127 pinR1 - - L - - - Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
COCFCCGP_01548 5.22e-106 - - - L - - - Integrase
COCFCCGP_01552 1.33e-19 - - - - - - - -
COCFCCGP_01554 1.77e-272 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
COCFCCGP_01555 1.72e-167 jag - - S ko:K06346 - ko00000 R3H domain protein
COCFCCGP_01556 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
COCFCCGP_01557 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
COCFCCGP_01558 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
COCFCCGP_01559 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
COCFCCGP_01560 1.49e-314 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
COCFCCGP_01561 2.44e-147 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
COCFCCGP_01562 4.4e-114 - 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase, GNAT family
COCFCCGP_01563 3.88e-205 - - - S - - - reductase
COCFCCGP_01565 0.0 - - - S - - - amidohydrolase
COCFCCGP_01566 6.13e-149 - - - M - - - Glycosyl transferase
COCFCCGP_01568 5.67e-198 - - - - - - - -
COCFCCGP_01569 6.09e-162 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
COCFCCGP_01570 3.14e-177 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
COCFCCGP_01571 1.74e-195 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
COCFCCGP_01572 1.31e-193 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
COCFCCGP_01573 2.83e-204 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
COCFCCGP_01574 1.45e-170 - - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C-terminal domain protein
COCFCCGP_01575 6.63e-174 - - - P ko:K02006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
COCFCCGP_01576 2.86e-184 - - - P ko:K02008 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
COCFCCGP_01577 2.33e-238 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PDGLE domain
COCFCCGP_01578 2.43e-95 - - - U - - - Important for reducing fluoride concentration in the cell, thus reducing its toxicity
COCFCCGP_01579 1.65e-55 - - - U - - - Important for reducing fluoride concentration in the cell, thus reducing its toxicity
COCFCCGP_01580 3.74e-206 ureD - - O ko:K03190 - ko00000 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
COCFCCGP_01581 2.42e-146 ureG - - KO ko:K03189 - ko00000 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
COCFCCGP_01582 2.94e-113 ureF - - O ko:K03188 - ko00000 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
COCFCCGP_01587 2.42e-78 - - - L - - - Resolvase, N terminal domain
COCFCCGP_01588 2.61e-44 - - - S - - - Phage derived protein Gp49-like (DUF891)
COCFCCGP_01589 3.93e-34 - - - K - - - Helix-turn-helix domain
COCFCCGP_01590 3.9e-09 - - - S - - - Domain of unknown function (DUF4145)
COCFCCGP_01591 7.89e-50 - - - - - - - -
COCFCCGP_01592 2.81e-126 - - - - - - - -
COCFCCGP_01593 0.0 - - - L - - - C-5 cytosine-specific DNA methylase
COCFCCGP_01594 5.22e-43 - - - - - - - -
COCFCCGP_01595 7.09e-180 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
COCFCCGP_01598 5.67e-293 - - - S ko:K06919 - ko00000 Virulence-associated protein E
COCFCCGP_01599 1.87e-175 - - - S - - - Bifunctional DNA primase/polymerase, N-terminal
COCFCCGP_01600 2.84e-120 - - - - - - - -
COCFCCGP_01601 8.69e-181 - - - L - - - AAA domain
COCFCCGP_01602 0.0 - - - L - - - Helicase C-terminal domain protein
COCFCCGP_01604 1.09e-100 - - - S - - - Siphovirus Gp157
COCFCCGP_01606 4.37e-43 - - - - - - - -
COCFCCGP_01609 6.94e-16 - - - S - - - Hypothetical protein (DUF2513)
COCFCCGP_01611 1.75e-50 - - - - - - - -
COCFCCGP_01613 8.81e-19 - - - K - - - Peptidase S24-like
COCFCCGP_01614 2.48e-21 - - - E - - - Zn peptidase
COCFCCGP_01615 1.57e-51 - - - - - - - -
COCFCCGP_01616 2.82e-37 - - - S - - - Domain of unknown function (DUF4352)
COCFCCGP_01617 1.28e-52 - - - V - - - Abi-like protein
COCFCCGP_01618 3.7e-182 int2 - - L - - - Belongs to the 'phage' integrase family
COCFCCGP_01625 5.77e-128 ydaM - - M - - - Glycosyl transferase family group 2
COCFCCGP_01626 4.36e-287 - - - G - - - Glycosyl hydrolases family 8
COCFCCGP_01627 1.05e-176 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
COCFCCGP_01628 0.0 mycA 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
COCFCCGP_01629 2.26e-303 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
COCFCCGP_01630 3.26e-151 ktrA - - P ko:K03499 - ko00000,ko02000 domain protein
COCFCCGP_01631 6.26e-113 - - - Q - - - Methyltransferase
COCFCCGP_01632 5.66e-295 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
COCFCCGP_01633 7.72e-228 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
COCFCCGP_01634 3.23e-217 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
COCFCCGP_01635 4.14e-123 - - - S - - - NADPH-dependent FMN reductase
COCFCCGP_01636 2.89e-230 - - - S - - - Conserved hypothetical protein 698
COCFCCGP_01637 1.45e-85 - - - K - - - Transcriptional regulator, GntR family
COCFCCGP_01638 8.11e-203 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
COCFCCGP_01639 2.26e-145 - - - - - - - -
COCFCCGP_01640 1.35e-182 - - - G - - - MucBP domain
COCFCCGP_01641 7.43e-129 - - - S - - - Pfam:DUF3816
COCFCCGP_01642 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
COCFCCGP_01643 1.38e-37 - - - - - - - -
COCFCCGP_01644 3.69e-54 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
COCFCCGP_01645 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
COCFCCGP_01646 2.99e-289 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
COCFCCGP_01647 7.35e-249 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
COCFCCGP_01648 7.66e-228 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
COCFCCGP_01649 1.97e-53 - - - S - - - Protein of unknown function (DUF1797)
COCFCCGP_01650 6.49e-49 - - - - ko:K18829 - ko00000,ko02048 -
COCFCCGP_01652 0.0 snf - - KL - - - domain protein
COCFCCGP_01653 9.44e-187 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
COCFCCGP_01654 2.63e-264 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
COCFCCGP_01655 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
COCFCCGP_01656 1.71e-240 - 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 Belongs to the N(4) N(6)-methyltransferase family
COCFCCGP_01657 7.04e-107 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
COCFCCGP_01658 0.0 - - - L - - - DNA helicase
COCFCCGP_01659 3.16e-260 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
COCFCCGP_01661 0.0 gabT 2.6.1.19, 5.1.1.21 - E ko:K00823,ko:K20708 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
COCFCCGP_01662 0.0 ctrA - - E ko:K03294 - ko00000 amino acid
COCFCCGP_01663 5.71e-152 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
COCFCCGP_01664 1.41e-53 - 1.3.5.4 - S ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FMN binding
COCFCCGP_01665 2.31e-278 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 transporter
COCFCCGP_01670 8.47e-169 - - - L - - - Belongs to the 'phage' integrase family
COCFCCGP_01672 5.7e-72 - - - - - - - -
COCFCCGP_01673 5.45e-93 - - - K - - - SIR2-like domain
COCFCCGP_01674 1.05e-90 tnpR1 - - L - - - Resolvase, N terminal domain
COCFCCGP_01675 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
COCFCCGP_01676 3.02e-171 gntR - - K - - - UbiC transcription regulator-associated domain protein
COCFCCGP_01677 4.73e-113 ebsC - - J ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
COCFCCGP_01678 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
COCFCCGP_01679 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
COCFCCGP_01680 0.0 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
COCFCCGP_01681 1.65e-241 ldhA 1.1.1.28 - C ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01504 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COCFCCGP_01682 4.17e-174 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
COCFCCGP_01683 7.89e-168 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
COCFCCGP_01684 1.55e-176 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
COCFCCGP_01685 1.39e-182 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
COCFCCGP_01686 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
COCFCCGP_01687 4.61e-97 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
COCFCCGP_01688 6.2e-96 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
COCFCCGP_01689 1.21e-286 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
COCFCCGP_01690 2.12e-167 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
COCFCCGP_01691 3.95e-203 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
COCFCCGP_01692 2.51e-47 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
COCFCCGP_01693 1.33e-226 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
COCFCCGP_01694 2.35e-101 - - - K - - - Transcriptional regulator, MarR family
COCFCCGP_01695 1.76e-94 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
COCFCCGP_01697 9.39e-256 xerS - - L - - - Belongs to the 'phage' integrase family
COCFCCGP_01698 1.35e-203 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
COCFCCGP_01699 2.74e-50 veg - - S - - - Biofilm formation stimulator VEG
COCFCCGP_01700 9.83e-204 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
COCFCCGP_01701 6.03e-128 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
COCFCCGP_01702 5.3e-200 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
COCFCCGP_01703 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
COCFCCGP_01704 2.74e-207 yunF - - F - - - Protein of unknown function DUF72
COCFCCGP_01706 1.02e-168 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
COCFCCGP_01707 2.58e-226 - - - - - - - -
COCFCCGP_01708 2.08e-283 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
COCFCCGP_01709 1.78e-214 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
COCFCCGP_01712 1.32e-79 - - - S ko:K21471 - ko00000,ko01000,ko01002,ko01011 dextransucrase activity
COCFCCGP_01713 7.54e-232 yueF - - S - - - AI-2E family transporter
COCFCCGP_01714 7.6e-298 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
COCFCCGP_01715 4.55e-118 - - - M - - - Glycosyl transferase family 2
COCFCCGP_01716 1.21e-24 - - - - - - - -
COCFCCGP_01717 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
COCFCCGP_01718 0.0 - - - S - - - SEC-C Motif Domain Protein
COCFCCGP_01719 1.19e-65 - - - - - - - -
COCFCCGP_01720 1.87e-178 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
COCFCCGP_01721 8.69e-190 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
COCFCCGP_01722 2.6e-149 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
COCFCCGP_01723 1.88e-290 - - - P - - - Chloride transporter, ClC family
COCFCCGP_01724 0.0 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
COCFCCGP_01725 5.65e-143 - - - I - - - Acid phosphatase homologues
COCFCCGP_01727 6.86e-176 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
COCFCCGP_01728 3.89e-106 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
COCFCCGP_01729 1.76e-258 - - - - - - - -
COCFCCGP_01730 1.76e-68 - - - - - - - -
COCFCCGP_01731 1.21e-48 - - - - - - - -
COCFCCGP_01732 9.21e-120 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
COCFCCGP_01733 6.12e-184 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
COCFCCGP_01734 2.21e-226 celE3 - - E - - - GDSL-like Lipase/Acylhydrolase family
COCFCCGP_01735 1.47e-287 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
COCFCCGP_01736 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
COCFCCGP_01737 1.62e-230 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
COCFCCGP_01739 3.56e-131 - - - M - - - Glycosyl hydrolases family 25
COCFCCGP_01741 1.34e-82 - - - S - - - dextransucrase activity
COCFCCGP_01742 6.55e-216 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
COCFCCGP_01743 6.38e-122 - - - L - - - Integrase
COCFCCGP_01744 1.18e-56 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
COCFCCGP_01745 1.28e-65 - - - S ko:K19157 - ko00000,ko01000,ko02048 Bacterial toxin of type II toxin-antitoxin system, YafQ
COCFCCGP_01747 1.63e-281 - - - - - - - -
COCFCCGP_01748 1.77e-55 - - - - - - - -
COCFCCGP_01749 1.37e-95 - - - KV ko:K01990 - ko00000,ko00002,ko02000 of ABC transporters with duplicated ATPase domains
COCFCCGP_01750 0.0 - - - J - - - Elongation factor G, domain IV
COCFCCGP_01751 1.06e-50 sugE - - U ko:K11741 - ko00000,ko02000 Multidrug resistance protein
COCFCCGP_01752 2.31e-27 - - - - - - - -
COCFCCGP_01753 2.6e-25 - 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 Type I restriction-modification system methyltransferase subunit()
COCFCCGP_01757 8.66e-89 arcD - - S - - - C4-dicarboxylate anaerobic carrier
COCFCCGP_01758 1.77e-188 arcD - - S - - - C4-dicarboxylate anaerobic carrier
COCFCCGP_01759 0.0 arcT - - E - - - Dipeptidase
COCFCCGP_01760 3.66e-274 - - - EGP - - - Transporter, major facilitator family protein
COCFCCGP_01761 0.0 gtfA 2.4.1.7 GH13 G ko:K00690 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose glucosyltransferase
COCFCCGP_01762 3.66e-183 - - - V - - - Beta-lactamase enzyme family
COCFCCGP_01763 7.09e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
COCFCCGP_01764 2.06e-152 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
COCFCCGP_01765 9.83e-148 - - - M - - - PFAM NLP P60 protein
COCFCCGP_01766 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
COCFCCGP_01767 2.12e-251 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
COCFCCGP_01768 2.36e-77 yodB - - K - - - Transcriptional regulator, HxlR family
COCFCCGP_01769 3.75e-119 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
COCFCCGP_01770 2.22e-185 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
COCFCCGP_01772 3.96e-54 - - - M - - - KxYKxGKxW signal domain protein
COCFCCGP_01773 1.07e-154 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NLP P60 protein
COCFCCGP_01774 4.96e-40 - - - - - - - -
COCFCCGP_01775 8.04e-115 - - - S - - - Acyltransferase family
COCFCCGP_01776 4.85e-136 - - - M - - - Glycosyltransferase like family 2
COCFCCGP_01777 1.36e-95 - - - S - - - Protein of unknown function (DUF3290)
COCFCCGP_01778 1.2e-148 - - - S - - - Protein of unknown function (DUF421)
COCFCCGP_01779 3.46e-208 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
COCFCCGP_01780 1.01e-28 - - - - - - - -
COCFCCGP_01781 8e-117 ntd 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside
COCFCCGP_01782 4.68e-197 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
COCFCCGP_01783 2.54e-60 yrvD - - S - - - Pfam:DUF1049
COCFCCGP_01785 1.47e-41 - - - S - - - Phage derived protein Gp49-like (DUF891)
COCFCCGP_01786 2.6e-27 - - - K - - - Helix-turn-helix XRE-family like proteins
COCFCCGP_01787 7.05e-101 - - - I - - - alpha/beta hydrolase fold
COCFCCGP_01788 3.55e-147 frnE 5.3.4.1 - Q ko:K01829 - ko00000,ko01000 DSBA-like thioredoxin domain
COCFCCGP_01789 6.14e-71 - - - - - - - -
COCFCCGP_01790 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
COCFCCGP_01791 3.81e-274 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
COCFCCGP_01792 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
COCFCCGP_01793 5.24e-114 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
COCFCCGP_01794 1.13e-247 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
COCFCCGP_01795 1.79e-84 - - - - - - - -
COCFCCGP_01796 5.25e-279 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 Transporter, major facilitator family protein
COCFCCGP_01797 4.04e-48 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 ThiS family
COCFCCGP_01798 3.25e-84 moaE 2.8.1.12 - H ko:K03635,ko:K21142 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 MoaE protein
COCFCCGP_01799 7.28e-101 - - - S - - - Flavodoxin
COCFCCGP_01800 4.18e-165 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
COCFCCGP_01801 4.82e-180 fecE 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
COCFCCGP_01802 7.67e-229 fecB - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
COCFCCGP_01803 7.92e-221 - - - - - - - -
COCFCCGP_01804 6.34e-95 - - - - - - - -
COCFCCGP_01805 1.54e-234 - - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
COCFCCGP_01806 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
COCFCCGP_01807 4.7e-240 - - - - - - - -
COCFCCGP_01809 2.19e-97 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
COCFCCGP_01810 3.7e-123 - - - K - - - acetyltransferase
COCFCCGP_01811 2.7e-203 - - - - - - - -
COCFCCGP_01812 1.26e-243 flp - - V - - - Beta-lactamase
COCFCCGP_01813 7.15e-122 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
COCFCCGP_01814 5.66e-158 - - - S ko:K07507 - ko00000,ko02000 MgtC family
COCFCCGP_01815 1.3e-50 - - - S - - - GyrI-like small molecule binding domain
COCFCCGP_01816 1.08e-89 - - - S - - - GyrI-like small molecule binding domain
COCFCCGP_01818 6.38e-151 - - - S - - - Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
COCFCCGP_01819 1.3e-65 azlD - - E - - - Branched-chain amino acid transport
COCFCCGP_01820 2.19e-153 azlC - - E - - - azaleucine resistance protein AzlC
COCFCCGP_01821 4.47e-74 - - - K - - - Aminotransferase class I and II
COCFCCGP_01822 1.26e-192 - - - K - - - Aminotransferase class I and II
COCFCCGP_01823 6.07e-292 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
COCFCCGP_01824 1.8e-316 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
COCFCCGP_01825 7.28e-138 - - - NU - - - mannosyl-glycoprotein
COCFCCGP_01826 4.65e-183 - - - S - - - Putative ABC-transporter type IV
COCFCCGP_01827 0.0 - - - S - - - ABC transporter, ATP-binding protein
COCFCCGP_01828 5.27e-64 - - - - - - - -
COCFCCGP_01830 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
COCFCCGP_01831 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
COCFCCGP_01832 1.89e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
COCFCCGP_01833 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
COCFCCGP_01834 4.72e-108 - - - - - - - -
COCFCCGP_01835 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 associated with various cellular activities
COCFCCGP_01836 2.49e-43 - - - - - - - -
COCFCCGP_01837 6.83e-274 - - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
COCFCCGP_01838 3.24e-226 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COCFCCGP_01839 6.86e-98 - - - O - - - OsmC-like protein
COCFCCGP_01840 1.6e-76 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
COCFCCGP_01842 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
COCFCCGP_01846 4.87e-106 - - - M - - - Glycosyl transferases group 1
COCFCCGP_01848 4.34e-50 - - - M - - - Glycosyltransferase like family 2
COCFCCGP_01849 3.8e-43 - - GT2 S ko:K12990 ko02024,ko02025,map02024,map02025 ko00000,ko00001,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
COCFCCGP_01850 4.82e-105 galnac-T15 - - M ko:K07011 - ko00000 Glycosyltransferase like family 2
COCFCCGP_01851 2.84e-101 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
COCFCCGP_01853 1.5e-280 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
COCFCCGP_01854 2.56e-104 - - - S - - - Family of unknown function (DUF5449)
COCFCCGP_01855 1.55e-223 - 4.1.1.22 - H ko:K01590 ko00340,ko01100,ko01110,map00340,map01100,map01110 ko00000,ko00001,ko01000 Histidine carboxylase PI chain
COCFCCGP_01856 0.0 - - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
COCFCCGP_01858 0.0 - - - L - - - PLD-like domain
COCFCCGP_01859 1.14e-121 mrr2 - - L ko:K07448 - ko00000,ko02048 restriction endonuclease
COCFCCGP_01860 1.17e-215 - - - L ko:K07448 - ko00000,ko02048 restriction endonuclease
COCFCCGP_01861 4e-109 - - - M - - - biosynthesis protein
COCFCCGP_01862 6.08e-235 cps3F - - - - - - -
COCFCCGP_01863 5.13e-126 - - - S - - - enterobacterial common antigen metabolic process
COCFCCGP_01865 2.64e-87 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NLP P60 protein
COCFCCGP_01866 3.42e-46 - - - - - - - -
COCFCCGP_01867 1.74e-127 araP - - U - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
COCFCCGP_01868 1.76e-143 - - - F - - - NUDIX domain
COCFCCGP_01869 1.5e-289 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
COCFCCGP_01870 1.56e-102 pncA - - Q - - - Isochorismatase family
COCFCCGP_01871 1.65e-83 yju3 - - I - - - Serine aminopeptidase, S33
COCFCCGP_01872 1.4e-34 - - - K - - - TRANSCRIPTIONal
COCFCCGP_01873 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
COCFCCGP_01874 1.98e-263 coiA - - S ko:K06198 - ko00000 Competence protein
COCFCCGP_01875 3.28e-156 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
COCFCCGP_01876 2.02e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
COCFCCGP_01877 1.31e-103 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
COCFCCGP_01878 6.47e-149 - - - S - - - Membrane
COCFCCGP_01879 2.5e-164 - - - O - - - Zinc-dependent metalloprotease
COCFCCGP_01880 9.38e-115 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
COCFCCGP_01881 4.16e-200 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
COCFCCGP_01883 5.98e-14 - - - - - - - -
COCFCCGP_01884 0.0 - - - L - - - Helicase C-terminal domain protein
COCFCCGP_01885 3.25e-60 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
COCFCCGP_01886 3.74e-213 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
COCFCCGP_01887 1.71e-202 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
COCFCCGP_01888 2.93e-111 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
COCFCCGP_01889 1.33e-130 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
COCFCCGP_01890 1.63e-142 yvgN - - S - - - Aldo keto reductase
COCFCCGP_01893 3.62e-92 - - - L - - - Helix-turn-helix domain
COCFCCGP_01894 5.64e-175 - - - L ko:K07497 - ko00000 hmm pf00665
COCFCCGP_01895 1.85e-20 - - - L - - - transposase IS116 IS110 IS902 family protein
COCFCCGP_01897 1.02e-27 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
COCFCCGP_01898 1.42e-149 ywqD - - D - - - Capsular exopolysaccharide family
COCFCCGP_01899 2.77e-177 epsB - - M - - - biosynthesis protein
COCFCCGP_01900 3.28e-215 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
COCFCCGP_01901 6.74e-53 - - - K - - - Transcriptional regulator, HxlR family
COCFCCGP_01902 2.24e-110 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
COCFCCGP_01903 5.74e-160 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
COCFCCGP_01904 3.58e-253 tagE 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
COCFCCGP_01906 3.3e-203 - - - J - - - Methyltransferase
COCFCCGP_01907 2.1e-288 oxlT - - P ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
COCFCCGP_01908 9.73e-146 fnr - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
COCFCCGP_01909 1.01e-120 dpsB - - P - - - Belongs to the Dps family
COCFCCGP_01910 1.35e-46 - - - C - - - Heavy-metal-associated domain
COCFCCGP_01911 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 E1-E2 ATPase
COCFCCGP_01912 1.4e-147 yjbH - - Q - - - Thioredoxin
COCFCCGP_01913 7.45e-150 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
COCFCCGP_01914 7.22e-197 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
COCFCCGP_01915 1.13e-220 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
COCFCCGP_01916 1.9e-94 - - - L - - - Transposase
COCFCCGP_01917 1.72e-193 - - - L - - - Transposase
COCFCCGP_01919 2.26e-133 - - - L - - - Belongs to the 'phage' integrase family
COCFCCGP_01921 2.7e-104 - - - K ko:K03719 - ko00000,ko03000,ko03036 AsnC family
COCFCCGP_01922 1.13e-291 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
COCFCCGP_01925 0.0 - - - S - - - Putative peptidoglycan binding domain
COCFCCGP_01926 4.83e-215 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
COCFCCGP_01927 5.26e-174 - - - I - - - alpha/beta hydrolase fold
COCFCCGP_01928 6.7e-38 - - - - - - - -
COCFCCGP_01929 2.47e-230 - - - L - - - COG2826 Transposase and inactivated derivatives, IS30 family
COCFCCGP_01930 3.94e-122 - - - K - - - DNA-templated transcription, initiation
COCFCCGP_01931 3.26e-48 - - - - - - - -
COCFCCGP_01932 1.15e-215 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
COCFCCGP_01933 4.76e-59 - - - S - - - Pfam:DUF59
COCFCCGP_01934 7.76e-91 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
COCFCCGP_01935 4.29e-310 - - - E - - - amino acid
COCFCCGP_01936 4.49e-180 yfhR3 - - S ko:K06889 - ko00000 Serine hydrolase (FSH1)
COCFCCGP_01937 0.0 - - - O - - - Arylsulfotransferase (ASST)
COCFCCGP_01938 5.61e-293 - - - L - - - Integrase core domain
COCFCCGP_01939 4.31e-180 - - - L - - - Bacterial dnaA protein
COCFCCGP_01940 5.14e-70 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
COCFCCGP_01941 9.42e-57 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
COCFCCGP_01942 2.71e-103 usp5 - - T - - - universal stress protein
COCFCCGP_01943 3.1e-127 - - - L - - - Helix-turn-helix domain
COCFCCGP_01944 2e-205 - - - L ko:K07497 - ko00000 hmm pf00665
COCFCCGP_01945 8.91e-293 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
COCFCCGP_01946 6.64e-254 - - - L - - - PFAM transposase, IS4 family protein
COCFCCGP_01947 3.19e-305 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
COCFCCGP_01948 5.41e-24 - - - K - - - Cro/C1-type HTH DNA-binding domain
COCFCCGP_01950 4.13e-228 - - - L - - - Belongs to the 'phage' integrase family
COCFCCGP_01951 1.26e-18 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
COCFCCGP_01952 5.21e-191 - - - K - - - Helix-turn-helix XRE-family like proteins
COCFCCGP_01953 1.58e-302 - - - L - - - Integrase core domain
COCFCCGP_01955 9.39e-39 - - - - - - - -
COCFCCGP_01956 2.02e-217 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
COCFCCGP_01958 4.95e-40 cspA - - K ko:K03704 - ko00000,ko03000 Cold shock protein
COCFCCGP_01969 3.62e-140 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
COCFCCGP_01970 2.49e-87 - - - S - - - Belongs to the HesB IscA family
COCFCCGP_01972 1.17e-49 hsdS 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain
COCFCCGP_01978 6.42e-50 B4168_4126 - - L ko:K07493 - ko00000 Transposase

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)