ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
MLDBCPCB_00001 4.17e-174 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MLDBCPCB_00002 5.75e-242 ldhA 1.1.1.28 - C ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01504 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MLDBCPCB_00003 0.0 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
MLDBCPCB_00004 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
MLDBCPCB_00005 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MLDBCPCB_00006 1.65e-113 ebsC - - J ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MLDBCPCB_00007 3.02e-171 gntR - - K - - - UbiC transcription regulator-associated domain protein
MLDBCPCB_00008 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
MLDBCPCB_00009 1.05e-310 - - - E - - - amino acid
MLDBCPCB_00010 1.83e-179 yfhR3 - - S ko:K06889 - ko00000 Serine hydrolase (FSH1)
MLDBCPCB_00011 9.75e-311 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
MLDBCPCB_00012 2.17e-213 - - - GK - - - ROK family
MLDBCPCB_00013 0.0 fusA1 - - J - - - elongation factor G
MLDBCPCB_00014 7.46e-106 uspA3 - - T - - - universal stress protein
MLDBCPCB_00015 1.17e-247 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
MLDBCPCB_00016 1.78e-83 - - - - - - - -
MLDBCPCB_00017 3.18e-11 - - - - - - - -
MLDBCPCB_00018 6.71e-151 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
MLDBCPCB_00019 1.12e-175 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MLDBCPCB_00020 1.37e-270 - - - EGP - - - Major Facilitator
MLDBCPCB_00021 0.0 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system Galactitol-specific IIC component
MLDBCPCB_00022 1.62e-229 - - - C - - - Zinc-binding dehydrogenase
MLDBCPCB_00023 3.46e-207 - - - - - - - -
MLDBCPCB_00024 1.3e-95 - - - K - - - Transcriptional regulator
MLDBCPCB_00025 2.53e-241 ybcH - - D ko:K06889 - ko00000 Alpha beta
MLDBCPCB_00026 6.35e-69 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
MLDBCPCB_00027 0.0 nhaK - - P ko:K03316 - ko00000 Sodium proton antiporter
MLDBCPCB_00028 6.5e-71 - - - - - - - -
MLDBCPCB_00029 2.91e-147 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
MLDBCPCB_00030 2.8e-315 - - - S ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MLDBCPCB_00031 8.59e-127 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
MLDBCPCB_00032 1.47e-171 - - - S ko:K07090 - ko00000 membrane transporter protein
MLDBCPCB_00033 7.72e-178 - - - IQ - - - KR domain
MLDBCPCB_00034 5.46e-233 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
MLDBCPCB_00035 3.42e-233 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
MLDBCPCB_00036 5e-194 - - - L ko:K07497 - ko00000 hmm pf00665
MLDBCPCB_00037 1.33e-162 - - - L - - - Helix-turn-helix domain
MLDBCPCB_00038 1.73e-75 - - - S - - - PD-(D/E)XK nuclease family transposase
MLDBCPCB_00039 9.45e-152 - - - S - - - HAD hydrolase, family IA, variant
MLDBCPCB_00040 0.0 yagE - - E - - - amino acid
MLDBCPCB_00041 4.16e-112 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
MLDBCPCB_00042 0.0 atp2C1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
MLDBCPCB_00043 8.65e-226 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
MLDBCPCB_00044 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MLDBCPCB_00045 1.25e-262 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MLDBCPCB_00046 2.49e-187 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MLDBCPCB_00047 4.43e-183 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MLDBCPCB_00048 1.21e-266 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MLDBCPCB_00049 1.97e-293 - - - - - - - -
MLDBCPCB_00050 1.77e-298 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
MLDBCPCB_00051 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
MLDBCPCB_00052 3.59e-97 - - - F - - - Nudix hydrolase
MLDBCPCB_00053 2.75e-132 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
MLDBCPCB_00054 1.27e-108 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
MLDBCPCB_00055 6.02e-34 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
MLDBCPCB_00056 4.65e-193 - - - - - - - -
MLDBCPCB_00057 8.65e-53 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain protein
MLDBCPCB_00058 2.14e-123 - - - K - - - Transcriptional regulator (TetR family)
MLDBCPCB_00059 0.0 yhgE - - V ko:K01421 - ko00000 domain protein
MLDBCPCB_00060 3.17e-233 - 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MLDBCPCB_00061 6.08e-13 - - - S - - - CsbD-like
MLDBCPCB_00062 1.34e-47 - - - S - - - Transglycosylase associated protein
MLDBCPCB_00063 5.19e-291 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MLDBCPCB_00064 9.5e-162 pgm3 - - G - - - phosphoglycerate mutase
MLDBCPCB_00065 2.31e-148 - - - S ko:K03975 - ko00000 SNARE associated Golgi protein
MLDBCPCB_00066 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
MLDBCPCB_00067 1.26e-44 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
MLDBCPCB_00068 1.77e-202 - - - EG - - - EamA-like transporter family
MLDBCPCB_00069 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MLDBCPCB_00070 5.62e-224 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
MLDBCPCB_00071 7.02e-288 - - - S ko:K07133 - ko00000 cog cog1373
MLDBCPCB_00073 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
MLDBCPCB_00075 0.0 - - - L - - - helicase
MLDBCPCB_00076 0.0 - - - J - - - Elongation factor G, domain IV
MLDBCPCB_00077 0.0 - - - L - - - Transposase
MLDBCPCB_00081 8.39e-77 - - - L - - - Resolvase, N terminal domain
MLDBCPCB_00083 6.62e-08 - - - S - - - Domain of unknown function (DUF3173)
MLDBCPCB_00084 3.3e-103 - - - L - - - Belongs to the 'phage' integrase family
MLDBCPCB_00085 2.1e-288 oxlT - - P ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
MLDBCPCB_00086 3.3e-203 - - - J - - - Methyltransferase
MLDBCPCB_00087 7.3e-98 yojA - - EG ko:K03299 - ko00000,ko02000 GntP family permease
MLDBCPCB_00088 7.55e-265 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
MLDBCPCB_00089 5.28e-76 - - - - - - - -
MLDBCPCB_00091 3.3e-265 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
MLDBCPCB_00092 4.37e-39 - - - - - - - -
MLDBCPCB_00093 1.69e-229 - - - I - - - Diacylglycerol kinase catalytic
MLDBCPCB_00094 9.99e-44 ykzG - - S - - - Belongs to the UPF0356 family
MLDBCPCB_00095 6.08e-102 - - - - - - - -
MLDBCPCB_00096 1.38e-132 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MLDBCPCB_00097 2.44e-267 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
MLDBCPCB_00098 9.42e-232 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
MLDBCPCB_00099 2.13e-311 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MLDBCPCB_00100 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
MLDBCPCB_00101 7.04e-63 yktA - - S - - - Belongs to the UPF0223 family
MLDBCPCB_00102 3.52e-177 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
MLDBCPCB_00103 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
MLDBCPCB_00104 7.54e-284 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
MLDBCPCB_00105 6.37e-60 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
MLDBCPCB_00106 6.8e-129 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
MLDBCPCB_00107 3.05e-116 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MLDBCPCB_00108 1.23e-251 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
MLDBCPCB_00109 3.4e-138 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
MLDBCPCB_00110 7.1e-116 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
MLDBCPCB_00111 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
MLDBCPCB_00112 9.21e-200 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
MLDBCPCB_00113 1.44e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
MLDBCPCB_00114 1.74e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MLDBCPCB_00115 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MLDBCPCB_00116 3.58e-208 - - - S - - - Tetratricopeptide repeat
MLDBCPCB_00117 4.94e-288 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MLDBCPCB_00118 5.54e-303 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MLDBCPCB_00119 2.06e-297 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MLDBCPCB_00120 2.01e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
MLDBCPCB_00121 1.11e-78 - - - S - - - mazG nucleotide pyrophosphohydrolase
MLDBCPCB_00122 2.44e-20 - - - - - - - -
MLDBCPCB_00123 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MLDBCPCB_00124 3.8e-316 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MLDBCPCB_00125 3.39e-226 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MLDBCPCB_00126 3.87e-200 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
MLDBCPCB_00127 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
MLDBCPCB_00128 1.46e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MLDBCPCB_00129 1.79e-121 - - - - - - - -
MLDBCPCB_00131 7.77e-159 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MLDBCPCB_00132 2.88e-270 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
MLDBCPCB_00133 4.18e-147 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MLDBCPCB_00134 2.7e-47 ynzC - - S - - - UPF0291 protein
MLDBCPCB_00135 1.6e-40 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
MLDBCPCB_00136 7.51e-152 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
MLDBCPCB_00137 5.9e-182 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
MLDBCPCB_00138 6.79e-65 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
MLDBCPCB_00139 5.9e-233 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MLDBCPCB_00140 3.54e-184 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
MLDBCPCB_00141 3.14e-197 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MLDBCPCB_00142 2.21e-167 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
MLDBCPCB_00143 4.23e-123 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MLDBCPCB_00144 1.83e-182 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MLDBCPCB_00145 1.18e-177 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
MLDBCPCB_00146 5.46e-297 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
MLDBCPCB_00147 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MLDBCPCB_00148 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MLDBCPCB_00149 1.1e-108 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
MLDBCPCB_00150 1.68e-274 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
MLDBCPCB_00151 5.93e-60 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
MLDBCPCB_00152 1.96e-65 ylxQ - - J - - - ribosomal protein
MLDBCPCB_00153 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MLDBCPCB_00154 1.38e-77 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MLDBCPCB_00155 1.21e-215 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MLDBCPCB_00156 5.19e-224 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
MLDBCPCB_00157 1.79e-84 - - - - - - - -
MLDBCPCB_00158 1.13e-247 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MLDBCPCB_00159 5.24e-114 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MLDBCPCB_00160 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
MLDBCPCB_00161 3.81e-274 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MLDBCPCB_00162 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MLDBCPCB_00163 0.0 pepD3 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MLDBCPCB_00164 1.01e-254 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
MLDBCPCB_00166 4.78e-222 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
MLDBCPCB_00168 7.92e-76 - - - - - - - -
MLDBCPCB_00169 4.65e-229 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
MLDBCPCB_00170 1.66e-165 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MLDBCPCB_00171 2.36e-69 - - - - - - - -
MLDBCPCB_00172 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MLDBCPCB_00173 1.88e-101 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MLDBCPCB_00174 2.09e-211 - - - G - - - Phosphotransferase enzyme family
MLDBCPCB_00175 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MLDBCPCB_00176 6.06e-168 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MLDBCPCB_00177 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
MLDBCPCB_00178 8.25e-31 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
MLDBCPCB_00179 2.34e-92 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
MLDBCPCB_00180 1.98e-232 rihA - - F ko:K01250 - ko00000,ko01000 Inosine-uridine preferring nucleoside hydrolase
MLDBCPCB_00181 7.47e-238 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MLDBCPCB_00182 2.78e-123 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
MLDBCPCB_00183 2.64e-286 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
MLDBCPCB_00184 2.72e-102 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MLDBCPCB_00185 4.08e-143 - - - T ko:K10716 - ko00000,ko02000 Ion transport 2 domain protein
MLDBCPCB_00186 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
MLDBCPCB_00187 3.07e-265 - - - G - - - Transporter, major facilitator family protein
MLDBCPCB_00188 1.43e-141 yvrI - - K ko:K03091,ko:K03093 - ko00000,ko03021 sigma factor activity
MLDBCPCB_00189 9.54e-85 yuxO - - Q - - - Thioesterase superfamily
MLDBCPCB_00190 6.96e-201 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MLDBCPCB_00191 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MLDBCPCB_00192 5.19e-27 - - - - - - - -
MLDBCPCB_00193 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
MLDBCPCB_00194 2.32e-43 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain
MLDBCPCB_00195 5.43e-185 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
MLDBCPCB_00196 1.07e-301 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
MLDBCPCB_00197 6.39e-299 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MLDBCPCB_00198 9.11e-106 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
MLDBCPCB_00199 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
MLDBCPCB_00200 1.18e-76 - - - S - - - Iron-sulfur cluster assembly protein
MLDBCPCB_00201 3.86e-205 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
MLDBCPCB_00202 5.87e-147 nreC - - K ko:K07696 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 PFAM regulatory protein LuxR
MLDBCPCB_00203 1.43e-51 - - - S - - - Cytochrome B5
MLDBCPCB_00204 3.19e-201 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
MLDBCPCB_00205 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
MLDBCPCB_00206 4.43e-191 - - - O - - - Band 7 protein
MLDBCPCB_00207 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 LytS YhcK-type transmembrane receptor domain protein
MLDBCPCB_00208 8.31e-169 lytT - - K ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator receiver
MLDBCPCB_00209 3.69e-87 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 LrgA family
MLDBCPCB_00210 4.38e-161 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 LrgB-like family
MLDBCPCB_00211 3.4e-229 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
MLDBCPCB_00212 5.79e-214 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
MLDBCPCB_00213 2.43e-241 galR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding protein-like domain
MLDBCPCB_00214 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
MLDBCPCB_00215 5.52e-119 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
MLDBCPCB_00216 8.91e-248 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MLDBCPCB_00217 4.11e-274 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
MLDBCPCB_00218 1.71e-217 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
MLDBCPCB_00219 2.1e-219 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
MLDBCPCB_00220 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
MLDBCPCB_00221 9.09e-113 ypmB - - S - - - Protein conserved in bacteria
MLDBCPCB_00222 1.75e-161 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
MLDBCPCB_00223 5.69e-207 - - - EG - - - EamA-like transporter family
MLDBCPCB_00224 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
MLDBCPCB_00225 7.01e-153 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MLDBCPCB_00226 1.17e-135 ypsA - - S - - - Belongs to the UPF0398 family
MLDBCPCB_00227 6.82e-74 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MLDBCPCB_00228 1.01e-109 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
MLDBCPCB_00229 3.43e-282 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
MLDBCPCB_00230 4.44e-91 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
MLDBCPCB_00231 2.58e-85 esbA - - S - - - Family of unknown function (DUF5322)
MLDBCPCB_00232 1.92e-91 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MLDBCPCB_00233 5.61e-222 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MLDBCPCB_00234 9.15e-264 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
MLDBCPCB_00235 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
MLDBCPCB_00236 0.0 FbpA - - K - - - Fibronectin-binding protein
MLDBCPCB_00237 1.2e-206 - - - S - - - EDD domain protein, DegV family
MLDBCPCB_00238 7.49e-124 - - - - - - - -
MLDBCPCB_00239 3.04e-154 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
MLDBCPCB_00240 2.07e-202 gspA - - M - - - family 8
MLDBCPCB_00241 5.98e-206 - - - S - - - Alpha beta hydrolase
MLDBCPCB_00242 7.5e-122 - - - K - - - Acetyltransferase (GNAT) domain
MLDBCPCB_00243 8.61e-308 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
MLDBCPCB_00244 1.02e-51 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
MLDBCPCB_00245 2.99e-218 yvgN - - C - - - Aldo keto reductase
MLDBCPCB_00246 7.79e-204 rlrB - - K - - - LysR substrate binding domain protein
MLDBCPCB_00247 2.91e-109 - - - C - - - Flavodoxin
MLDBCPCB_00248 6.14e-104 - - - S - - - Cupin domain
MLDBCPCB_00249 6.68e-98 - - - S - - - UPF0756 membrane protein
MLDBCPCB_00250 3.38e-308 - - - U - - - Belongs to the major facilitator superfamily
MLDBCPCB_00251 2.39e-98 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
MLDBCPCB_00252 5.51e-316 yhdP - - S - - - Transporter associated domain
MLDBCPCB_00253 0.0 ubiB - - S ko:K03688 - ko00000 ABC1 family
MLDBCPCB_00254 2.37e-184 - - - S - - - DUF218 domain
MLDBCPCB_00255 3.39e-90 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MLDBCPCB_00256 1.3e-78 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MLDBCPCB_00257 6.28e-73 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MLDBCPCB_00258 0.0 uvrA2 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC, A subunit
MLDBCPCB_00259 2.04e-158 - - - S - - - SNARE associated Golgi protein
MLDBCPCB_00260 2.11e-290 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
MLDBCPCB_00261 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MLDBCPCB_00263 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
MLDBCPCB_00264 1.64e-200 endA - - V ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
MLDBCPCB_00265 0.0 - - - I - - - Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MLDBCPCB_00266 7.09e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MLDBCPCB_00267 2.06e-152 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
MLDBCPCB_00268 6.92e-148 - - - M - - - PFAM NLP P60 protein
MLDBCPCB_00269 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MLDBCPCB_00270 2.12e-251 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MLDBCPCB_00271 2.36e-77 yodB - - K - - - Transcriptional regulator, HxlR family
MLDBCPCB_00272 3.75e-119 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
MLDBCPCB_00273 2.22e-185 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MLDBCPCB_00274 1.79e-60 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
MLDBCPCB_00275 3.89e-215 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MLDBCPCB_00276 9.16e-91 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
MLDBCPCB_00277 7.99e-293 - - - V - - - MatE
MLDBCPCB_00278 0.0 potE - - E - - - Amino Acid
MLDBCPCB_00279 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MLDBCPCB_00280 1.38e-155 csrR - - K - - - response regulator
MLDBCPCB_00281 7.21e-39 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
MLDBCPCB_00282 1.01e-129 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
MLDBCPCB_00283 9.69e-274 ylbM - - S - - - Belongs to the UPF0348 family
MLDBCPCB_00284 1.1e-179 yqeM - - Q - - - Methyltransferase
MLDBCPCB_00285 1.9e-79 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MLDBCPCB_00286 3.6e-146 yqeK - - H - - - Hydrolase, HD family
MLDBCPCB_00287 4.7e-156 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MLDBCPCB_00288 5.4e-63 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
MLDBCPCB_00289 5.44e-279 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
MLDBCPCB_00290 3.17e-124 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
MLDBCPCB_00291 2.23e-73 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MLDBCPCB_00292 1.82e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
MLDBCPCB_00293 1.07e-110 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MLDBCPCB_00294 9.62e-219 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
MLDBCPCB_00295 7.76e-274 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
MLDBCPCB_00296 2.82e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MLDBCPCB_00297 5.91e-129 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MLDBCPCB_00298 2.74e-204 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MLDBCPCB_00299 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MLDBCPCB_00300 3.26e-150 - - - S - - - Protein of unknown function (DUF1275)
MLDBCPCB_00301 6.48e-154 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
MLDBCPCB_00302 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
MLDBCPCB_00303 8.55e-46 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
MLDBCPCB_00304 7.39e-64 - - - S - - - Bacterial toxin of type II toxin-antitoxin system, YafQ
MLDBCPCB_00305 1.63e-152 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MLDBCPCB_00306 2.95e-75 ytpP - - CO - - - Thioredoxin
MLDBCPCB_00307 3.23e-75 - - - S - - - Small secreted protein
MLDBCPCB_00308 1.21e-213 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
MLDBCPCB_00309 2.32e-233 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
MLDBCPCB_00310 5.88e-126 tagE3 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
MLDBCPCB_00311 6.79e-183 tagE3 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
MLDBCPCB_00312 1.58e-310 - 2.1.1.72, 3.1.21.3 AA10,CBM73 M ko:K01154,ko:K02014,ko:K03933,ko:K07316 - ko00000,ko01000,ko02000,ko02048 domain protein
MLDBCPCB_00313 7.51e-77 - 2.1.1.72, 3.1.21.3 AA10,CBM73 M ko:K01154,ko:K02014,ko:K03933,ko:K07316 - ko00000,ko01000,ko02000,ko02048 domain protein
MLDBCPCB_00314 3.31e-37 - - - S - - - YSIRK type signal peptide
MLDBCPCB_00315 1.85e-157 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MLDBCPCB_00316 6.64e-279 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
MLDBCPCB_00317 2.7e-175 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MLDBCPCB_00318 6.82e-99 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
MLDBCPCB_00320 3.96e-178 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MLDBCPCB_00321 0.0 yhaN - - L - - - AAA domain
MLDBCPCB_00322 2.62e-282 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
MLDBCPCB_00323 3.75e-77 yheA - - S - - - Belongs to the UPF0342 family
MLDBCPCB_00324 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
MLDBCPCB_00325 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
MLDBCPCB_00326 2.15e-194 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
MLDBCPCB_00327 3.88e-213 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
MLDBCPCB_00329 1.49e-54 - - - - - - - -
MLDBCPCB_00330 9.3e-61 - - - - - - - -
MLDBCPCB_00331 1.62e-277 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 dihydropteroate synthase
MLDBCPCB_00332 2.97e-136 folQ 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
MLDBCPCB_00333 8.17e-285 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
MLDBCPCB_00334 1.37e-135 folE 2.7.6.3, 3.5.4.16 - F ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase 1
MLDBCPCB_00335 4.71e-114 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
MLDBCPCB_00336 6.82e-72 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MLDBCPCB_00337 2.11e-89 - - - - - - - -
MLDBCPCB_00339 9.17e-59 - - - - - - - -
MLDBCPCB_00340 4.68e-145 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
MLDBCPCB_00341 1.52e-43 - - - - - - - -
MLDBCPCB_00342 1.63e-207 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MLDBCPCB_00343 8.42e-237 rbsR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
MLDBCPCB_00344 3.08e-146 - - - - - - - -
MLDBCPCB_00345 3.06e-150 dgk2 - - F - - - deoxynucleoside kinase
MLDBCPCB_00346 1.11e-224 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MLDBCPCB_00347 4.4e-112 - - - T - - - Belongs to the universal stress protein A family
MLDBCPCB_00348 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
MLDBCPCB_00349 1.61e-192 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MLDBCPCB_00350 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
MLDBCPCB_00351 1.45e-55 - - - - - - - -
MLDBCPCB_00352 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
MLDBCPCB_00353 2.71e-280 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MLDBCPCB_00354 4.29e-119 tag1 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
MLDBCPCB_00355 0.0 - - - EGP - - - Major Facilitator
MLDBCPCB_00356 1.25e-111 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
MLDBCPCB_00357 1.72e-303 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
MLDBCPCB_00358 8.28e-135 - - - V - - - VanZ like family
MLDBCPCB_00359 7.03e-33 - - - - - - - -
MLDBCPCB_00360 5.03e-111 - - - S - - - Short repeat of unknown function (DUF308)
MLDBCPCB_00361 1.08e-101 - - - S - - - Psort location Cytoplasmic, score
MLDBCPCB_00362 0.0 umuC - - L ko:K03502 - ko00000,ko03400 impB/mucB/samB family C-terminal domain
MLDBCPCB_00363 4.63e-101 hsp - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
MLDBCPCB_00364 1.29e-196 yeaE - - S - - - Aldo keto
MLDBCPCB_00366 0.0 - - - L - - - PLD-like domain
MLDBCPCB_00367 1.5e-48 higA - - K ko:K21498 - ko00000,ko02048 addiction module antidote protein HigA
MLDBCPCB_00368 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
MLDBCPCB_00369 3.98e-106 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
MLDBCPCB_00370 1.68e-229 - - - L - - - Belongs to the 'phage' integrase family
MLDBCPCB_00371 9.77e-65 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
MLDBCPCB_00372 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
MLDBCPCB_00373 2.65e-218 - - - S - - - Protein of unknown function DUF262
MLDBCPCB_00374 4.57e-104 - - - S - - - Protein of unknown function (DUF805)
MLDBCPCB_00375 1.26e-60 - - - - - - - -
MLDBCPCB_00376 1.81e-41 - - - - - - - -
MLDBCPCB_00377 1.09e-62 - - - - - - - -
MLDBCPCB_00378 1.98e-123 - - - K - - - Acetyltransferase (GNAT) domain
MLDBCPCB_00379 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
MLDBCPCB_00380 1.33e-295 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
MLDBCPCB_00381 1.62e-232 - - - K ko:K02525 - ko00000,ko03000 Transcriptional regulator, LacI family
MLDBCPCB_00382 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
MLDBCPCB_00383 1.14e-124 - - - - - - - -
MLDBCPCB_00384 3.09e-35 - - - - - - - -
MLDBCPCB_00385 2.71e-81 asp1 - - S - - - Asp23 family, cell envelope-related function
MLDBCPCB_00386 7.63e-117 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
MLDBCPCB_00388 9.14e-66 - - - - - - - -
MLDBCPCB_00389 2.49e-87 - - - S - - - Belongs to the HesB IscA family
MLDBCPCB_00390 5.18e-222 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
MLDBCPCB_00391 8.08e-110 - - - F - - - NUDIX domain
MLDBCPCB_00392 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MLDBCPCB_00393 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MLDBCPCB_00394 1.9e-139 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MLDBCPCB_00395 7.89e-212 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
MLDBCPCB_00396 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MLDBCPCB_00397 7.84e-207 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
MLDBCPCB_00398 2.05e-180 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MLDBCPCB_00399 1.99e-204 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MLDBCPCB_00400 1.33e-47 yozE - - S - - - Belongs to the UPF0346 family
MLDBCPCB_00401 4.05e-141 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
MLDBCPCB_00402 4.79e-221 - - - E - - - lipolytic protein G-D-S-L family
MLDBCPCB_00403 6.38e-196 WQ51_01275 - - S - - - EDD domain protein, DegV family
MLDBCPCB_00404 2.59e-144 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
MLDBCPCB_00405 3.38e-119 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MLDBCPCB_00406 3.61e-247 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MLDBCPCB_00407 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
MLDBCPCB_00408 4.94e-287 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MLDBCPCB_00409 9.5e-301 XK27_05225 - - S - - - Tetratricopeptide repeat protein
MLDBCPCB_00410 1.6e-54 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MLDBCPCB_00411 0.0 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
MLDBCPCB_00412 1e-272 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
MLDBCPCB_00413 3.8e-153 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
MLDBCPCB_00414 2.15e-83 - - - M - - - Lysin motif
MLDBCPCB_00415 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
MLDBCPCB_00416 7.6e-246 - - - S - - - Helix-turn-helix domain
MLDBCPCB_00417 2.65e-133 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MLDBCPCB_00418 1.67e-163 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MLDBCPCB_00419 1.35e-135 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MLDBCPCB_00420 1.95e-177 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MLDBCPCB_00421 3.67e-86 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MLDBCPCB_00422 2.35e-211 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
MLDBCPCB_00423 1.08e-214 yitL - - S ko:K00243 - ko00000 S1 domain
MLDBCPCB_00424 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
MLDBCPCB_00425 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
MLDBCPCB_00426 1.11e-41 - - - S - - - Protein of unknown function (DUF2929)
MLDBCPCB_00427 1.58e-301 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
MLDBCPCB_00428 1.85e-201 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MLDBCPCB_00429 2.2e-160 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
MLDBCPCB_00430 1.69e-278 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MLDBCPCB_00431 2.09e-265 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MLDBCPCB_00432 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MLDBCPCB_00433 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
MLDBCPCB_00434 2.14e-234 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
MLDBCPCB_00435 2.14e-189 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
MLDBCPCB_00436 1.08e-218 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MLDBCPCB_00437 2.11e-80 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
MLDBCPCB_00438 1.55e-109 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MLDBCPCB_00439 2.6e-234 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
MLDBCPCB_00440 4.11e-225 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MLDBCPCB_00441 1.71e-119 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
MLDBCPCB_00442 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
MLDBCPCB_00443 1.22e-197 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
MLDBCPCB_00444 5.87e-50 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
MLDBCPCB_00445 1.2e-234 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MLDBCPCB_00446 0.0 - - - O - - - Arylsulfotransferase (ASST)
MLDBCPCB_00447 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
MLDBCPCB_00448 1.53e-241 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MLDBCPCB_00449 7.93e-219 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MLDBCPCB_00450 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MLDBCPCB_00451 3.68e-125 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
MLDBCPCB_00452 0.0 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MLDBCPCB_00453 5.75e-103 yabR - - J ko:K07571 - ko00000 RNA binding
MLDBCPCB_00454 7.15e-75 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
MLDBCPCB_00455 1.18e-51 yabO - - J - - - S4 domain protein
MLDBCPCB_00456 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MLDBCPCB_00457 7.98e-132 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MLDBCPCB_00458 2.7e-145 - - - S - - - (CBS) domain
MLDBCPCB_00459 2.06e-188 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
MLDBCPCB_00460 1.59e-308 codA 3.5.4.1 - F ko:K01485 ko00240,ko00330,ko01100,map00240,map00330,map01100 ko00000,ko00001,ko01000 cytosine deaminase
MLDBCPCB_00461 0.0 - - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
MLDBCPCB_00462 1.3e-82 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
MLDBCPCB_00463 1.54e-269 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MLDBCPCB_00464 1.88e-80 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MLDBCPCB_00465 2.63e-08 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
MLDBCPCB_00466 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLDBCPCB_00467 1.23e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
MLDBCPCB_00468 1e-47 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLDBCPCB_00469 0.0 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MLDBCPCB_00470 4.83e-212 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
MLDBCPCB_00471 4.84e-241 - - - D - - - Domain of Unknown Function (DUF1542)
MLDBCPCB_00472 2.29e-158 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
MLDBCPCB_00473 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MLDBCPCB_00474 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MLDBCPCB_00475 1.06e-203 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
MLDBCPCB_00476 4.93e-123 lemA - - S ko:K03744 - ko00000 LemA family
MLDBCPCB_00477 2.71e-112 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MLDBCPCB_00478 1.51e-154 - - - G - - - Belongs to the phosphoglycerate mutase family
MLDBCPCB_00479 6.21e-207 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
MLDBCPCB_00480 6.08e-179 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MLDBCPCB_00481 1.51e-289 pps 2.7.9.2 - H ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
MLDBCPCB_00482 1.75e-161 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
MLDBCPCB_00483 7.58e-212 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MLDBCPCB_00484 3.07e-301 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MLDBCPCB_00485 9.43e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
MLDBCPCB_00486 5.29e-300 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MLDBCPCB_00487 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MLDBCPCB_00488 1.14e-81 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MLDBCPCB_00489 9.28e-89 ywiB - - S - - - Domain of unknown function (DUF1934)
MLDBCPCB_00490 4.82e-188 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 biotin lipoate A B protein ligase
MLDBCPCB_00491 0.0 ywfO - - S ko:K06885 - ko00000 HD domain protein
MLDBCPCB_00492 1.89e-189 yidA - - S - - - hydrolase
MLDBCPCB_00493 1.6e-100 - - - - - - - -
MLDBCPCB_00494 3.53e-229 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MLDBCPCB_00495 2.6e-313 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MLDBCPCB_00496 3.03e-190 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
MLDBCPCB_00497 4.12e-164 - - - U ko:K02075 - ko00000,ko00002,ko02000 ABC 3 transport family
MLDBCPCB_00498 2.31e-156 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MLDBCPCB_00499 1.66e-214 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
MLDBCPCB_00500 5.5e-203 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MLDBCPCB_00501 2.74e-50 veg - - S - - - Biofilm formation stimulator VEG
MLDBCPCB_00502 9.83e-204 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MLDBCPCB_00503 6.03e-128 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MLDBCPCB_00504 5.3e-200 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
MLDBCPCB_00505 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MLDBCPCB_00506 4.74e-208 yunF - - F - - - Protein of unknown function DUF72
MLDBCPCB_00508 5.9e-168 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
MLDBCPCB_00509 1.09e-227 - - - - - - - -
MLDBCPCB_00510 2.08e-283 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
MLDBCPCB_00511 2.53e-214 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
MLDBCPCB_00512 5.54e-243 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
MLDBCPCB_00513 5.96e-241 - 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 Belongs to the N(4) N(6)-methyltransferase family
MLDBCPCB_00514 7.04e-107 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
MLDBCPCB_00515 0.0 - - - L - - - DNA helicase
MLDBCPCB_00516 6.38e-260 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MLDBCPCB_00518 0.0 gabT 2.6.1.19, 5.1.1.21 - E ko:K00823,ko:K20708 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MLDBCPCB_00519 0.0 ctrA - - E ko:K03294 - ko00000 amino acid
MLDBCPCB_00520 5.71e-152 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MLDBCPCB_00521 1.41e-53 - 1.3.5.4 - S ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FMN binding
MLDBCPCB_00522 2.31e-278 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 transporter
MLDBCPCB_00523 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MLDBCPCB_00524 2.06e-108 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MLDBCPCB_00525 2.51e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MLDBCPCB_00526 1.97e-153 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
MLDBCPCB_00527 1.15e-263 - - - - - - - -
MLDBCPCB_00528 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MLDBCPCB_00529 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MLDBCPCB_00530 2.09e-143 - - - K - - - Bacterial regulatory proteins, tetR family
MLDBCPCB_00531 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MLDBCPCB_00532 1.39e-101 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
MLDBCPCB_00533 8.94e-250 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
MLDBCPCB_00534 4.62e-21 - - - S ko:K06889 - ko00000 Hydrolases of the alpha beta superfamily
MLDBCPCB_00535 1.51e-118 - - - S ko:K06889 - ko00000 Hydrolases of the alpha beta superfamily
MLDBCPCB_00541 7.78e-150 dgk2 - - F - - - deoxynucleoside kinase
MLDBCPCB_00542 0.0 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
MLDBCPCB_00544 2.79e-153 - - - I - - - phosphatase
MLDBCPCB_00545 5.02e-105 - - - S - - - Threonine/Serine exporter, ThrE
MLDBCPCB_00546 2.98e-166 - - - S - - - Putative threonine/serine exporter
MLDBCPCB_00547 2.17e-43 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
MLDBCPCB_00548 9.44e-161 mntR - - K ko:K03709 - ko00000,ko03000 iron dependent repressor
MLDBCPCB_00549 2.85e-212 - - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
MLDBCPCB_00550 7.33e-152 - - - S - - - membrane
MLDBCPCB_00551 2.72e-141 - - - S - - - VIT family
MLDBCPCB_00552 4.83e-108 - - - T - - - Belongs to the universal stress protein A family
MLDBCPCB_00553 1.14e-172 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MLDBCPCB_00554 3.85e-195 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MLDBCPCB_00555 1.06e-142 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MLDBCPCB_00556 2.11e-140 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MLDBCPCB_00557 8.69e-277 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
MLDBCPCB_00558 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MLDBCPCB_00559 9.15e-72 - - - - - - - -
MLDBCPCB_00560 1.26e-96 - - - K - - - MerR HTH family regulatory protein
MLDBCPCB_00561 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
MLDBCPCB_00562 1.91e-153 - - - S - - - Domain of unknown function (DUF4811)
MLDBCPCB_00563 2.24e-205 yjbO 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MLDBCPCB_00565 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MLDBCPCB_00566 5.59e-134 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
MLDBCPCB_00567 1.93e-241 - - - I - - - Alpha beta
MLDBCPCB_00568 0.0 qacA - - EGP - - - Major Facilitator
MLDBCPCB_00569 2.22e-151 - 3.2.2.27 - L ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Uracil-DNA glycosylase
MLDBCPCB_00570 0.0 - - - S - - - Putative threonine/serine exporter
MLDBCPCB_00571 7.21e-205 - - - K - - - LysR family
MLDBCPCB_00572 0.0 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
MLDBCPCB_00573 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
MLDBCPCB_00574 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MLDBCPCB_00575 0.0 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
MLDBCPCB_00576 1.13e-77 mleR - - K - - - LysR family
MLDBCPCB_00577 4.71e-114 mleR - - K - - - LysR family
MLDBCPCB_00578 2.87e-144 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MLDBCPCB_00579 1.35e-263 adh 1.1.1.1 - C ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding alcohol dehydrogenase family protein
MLDBCPCB_00580 0.0 - - - L - - - PFAM plasmid pRiA4b ORF-3 family protein
MLDBCPCB_00581 1.23e-212 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
MLDBCPCB_00582 0.0 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
MLDBCPCB_00583 1.36e-35 - - - - - - - -
MLDBCPCB_00584 3.67e-255 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
MLDBCPCB_00585 7.62e-97 - - - - - - - -
MLDBCPCB_00586 9.29e-290 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MLDBCPCB_00587 1.55e-109 - - - - - - - -
MLDBCPCB_00588 8.83e-205 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
MLDBCPCB_00589 9e-72 - - - S - - - Mazg nucleotide pyrophosphohydrolase
MLDBCPCB_00590 3.67e-46 - - - - - - - -
MLDBCPCB_00591 3.03e-83 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MLDBCPCB_00592 0.0 - - - E ko:K03294 - ko00000 amino acid
MLDBCPCB_00593 5.46e-183 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
MLDBCPCB_00594 5.33e-119 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MLDBCPCB_00595 2.17e-52 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
MLDBCPCB_00596 1.21e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
MLDBCPCB_00597 0.0 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MLDBCPCB_00598 4.23e-76 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MLDBCPCB_00599 4.94e-285 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MLDBCPCB_00600 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
MLDBCPCB_00601 1.57e-168 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MLDBCPCB_00602 1.81e-50 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
MLDBCPCB_00603 2.73e-240 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MLDBCPCB_00604 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MLDBCPCB_00605 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
MLDBCPCB_00606 1.05e-77 yloU - - S - - - Asp23 family, cell envelope-related function
MLDBCPCB_00607 1.1e-34 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
MLDBCPCB_00608 1.91e-156 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
MLDBCPCB_00609 5.46e-152 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
MLDBCPCB_00610 3.75e-212 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MLDBCPCB_00611 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
MLDBCPCB_00612 1.22e-167 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
MLDBCPCB_00613 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MLDBCPCB_00614 8.26e-222 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MLDBCPCB_00615 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MLDBCPCB_00616 4.44e-273 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MLDBCPCB_00617 6.66e-43 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MLDBCPCB_00618 4.37e-148 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
MLDBCPCB_00619 9e-72 - - - - - - - -
MLDBCPCB_00620 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
MLDBCPCB_00621 3.2e-100 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
MLDBCPCB_00622 1.69e-192 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
MLDBCPCB_00623 6.95e-205 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MLDBCPCB_00624 4.02e-58 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MLDBCPCB_00625 1.09e-309 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MLDBCPCB_00626 2.67e-191 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MLDBCPCB_00627 2.24e-92 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MLDBCPCB_00628 2.27e-93 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
MLDBCPCB_00629 2.02e-146 - - - J - - - 2'-5' RNA ligase superfamily
MLDBCPCB_00630 3.54e-255 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
MLDBCPCB_00631 3.84e-170 - - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MLDBCPCB_00632 5.07e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
MLDBCPCB_00633 1.77e-72 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
MLDBCPCB_00634 2.68e-67 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
MLDBCPCB_00635 7.77e-144 - - - K - - - Transcriptional regulator
MLDBCPCB_00638 4.21e-116 - - - S - - - Protein conserved in bacteria
MLDBCPCB_00639 1.53e-225 - - - - - - - -
MLDBCPCB_00640 4.87e-203 - - - - - - - -
MLDBCPCB_00641 1.54e-67 yitW - - S - - - Iron-sulfur cluster assembly protein
MLDBCPCB_00642 1.99e-131 msrA 1.8.4.11 - C ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MLDBCPCB_00643 3.42e-197 - - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
MLDBCPCB_00644 1.28e-18 - - - - - - - -
MLDBCPCB_00645 8.1e-281 araT 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MLDBCPCB_00646 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MLDBCPCB_00647 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
MLDBCPCB_00648 7.13e-227 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MLDBCPCB_00649 1.18e-30 - - - S - - - Protein of unknown function (DUF3042)
MLDBCPCB_00650 7.66e-88 yqhL - - P - - - Rhodanese-like protein
MLDBCPCB_00651 1.02e-234 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
MLDBCPCB_00652 7.07e-48 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
MLDBCPCB_00653 1.38e-59 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
MLDBCPCB_00654 1.43e-16 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
MLDBCPCB_00655 9.34e-130 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MLDBCPCB_00656 1.53e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
MLDBCPCB_00657 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
MLDBCPCB_00658 0.0 - - - S - - - membrane
MLDBCPCB_00659 1.33e-91 yneR - - S - - - Belongs to the HesB IscA family
MLDBCPCB_00660 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MLDBCPCB_00661 2.39e-301 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
MLDBCPCB_00662 9.19e-233 yueF - - S - - - AI-2E family transporter
MLDBCPCB_00663 0.0 csd1 3.5.1.28 - M ko:K01447,ko:K17733,ko:K19117 - ko00000,ko01000,ko01002,ko01011,ko02048 N-Acetylmuramoyl-L-alanine amidase
MLDBCPCB_00664 2.33e-202 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MLDBCPCB_00665 1.34e-262 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MLDBCPCB_00666 5.58e-140 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
MLDBCPCB_00667 1.65e-207 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MLDBCPCB_00668 0.0 - - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MLDBCPCB_00669 4.72e-75 - - - S - - - integral membrane protein
MLDBCPCB_00670 1.39e-209 ykoT - - M - - - Glycosyl transferase family 2
MLDBCPCB_00671 2.26e-90 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MLDBCPCB_00673 9.44e-89 - - - S - - - Acyltransferase family
MLDBCPCB_00674 1e-97 - - - S ko:K07011 - ko00000 Glycosyltransferase, group 2 family protein
MLDBCPCB_00675 7.27e-83 - - - S - - - Glycosyltransferase like family
MLDBCPCB_00676 3.13e-95 - - GT2 M ko:K12997 - ko00000,ko01000,ko01003,ko01005 Glycosyl transferase family 2
MLDBCPCB_00677 6.82e-38 - - - M - - - biosynthesis protein
MLDBCPCB_00678 2.45e-107 - - - - - - - -
MLDBCPCB_00679 8.59e-95 - - - M - - - transferase activity, transferring glycosyl groups
MLDBCPCB_00680 1.14e-263 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
MLDBCPCB_00681 1.75e-278 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
MLDBCPCB_00682 0.0 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
MLDBCPCB_00683 4.46e-46 - - - - - - - -
MLDBCPCB_00684 0.0 - - - G - - - Peptidase_C39 like family
MLDBCPCB_00685 0.0 spoIIQ - - M ko:K06386 - ko00000 Peptidase family M23
MLDBCPCB_00686 6.93e-154 - - - M - - - Bacterial sugar transferase
MLDBCPCB_00687 3.96e-225 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
MLDBCPCB_00688 2.23e-188 cps1D - - M - - - Domain of unknown function (DUF4422)
MLDBCPCB_00689 2.02e-175 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
MLDBCPCB_00690 2.53e-42 - - - - - - - -
MLDBCPCB_00691 1.26e-46 - - - S - - - Protein of unknown function (DUF2922)
MLDBCPCB_00692 7.47e-203 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
MLDBCPCB_00693 0.0 potE - - E - - - Amino Acid
MLDBCPCB_00694 0.0 arcD - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
MLDBCPCB_00695 3.27e-279 arcT - - E - - - Aminotransferase
MLDBCPCB_00696 1e-215 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
MLDBCPCB_00697 4.7e-103 ykuP - - C ko:K03839 - ko00000 Flavodoxin
MLDBCPCB_00698 4.94e-88 gtcA - - S - - - Teichoic acid glycosylation protein
MLDBCPCB_00699 2.02e-72 - - - - - - - -
MLDBCPCB_00700 2.09e-266 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MLDBCPCB_00702 2.04e-292 yfmL - - L - - - DEAD DEAH box helicase
MLDBCPCB_00703 5.34e-245 mocA - - S - - - Oxidoreductase
MLDBCPCB_00704 4.62e-81 - - - S - - - Domain of unknown function (DUF4828)
MLDBCPCB_00705 1.25e-136 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
MLDBCPCB_00706 1.86e-213 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
MLDBCPCB_00707 0.0 gshA 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
MLDBCPCB_00708 5.79e-250 - - - S - - - Protein of unknown function (DUF3114)
MLDBCPCB_00709 2.25e-105 yjcF 3.5.4.33, 4.4.1.8 - K ko:K02348,ko:K07000,ko:K11991,ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007,ko03016 protein acetylation
MLDBCPCB_00710 6.48e-153 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
MLDBCPCB_00711 1.8e-24 - - - - - - - -
MLDBCPCB_00712 1.2e-118 - - - K - - - Acetyltransferase (GNAT) family
MLDBCPCB_00713 1.05e-102 - - - K - - - LytTr DNA-binding domain
MLDBCPCB_00714 1.53e-97 - - - S - - - Protein of unknown function (DUF3021)
MLDBCPCB_00715 3.21e-214 - 3.2.1.96, 3.5.1.28 GH73 M ko:K01227,ko:K01447,ko:K13714,ko:K13731 ko00511,ko05100,map00511,map05100 ko00000,ko00001,ko01000 N-acetylmuramoyl-L-alanine amidase
MLDBCPCB_00716 1.27e-162 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
MLDBCPCB_00717 3.02e-135 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
MLDBCPCB_00718 2.12e-253 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MLDBCPCB_00719 5.14e-170 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MLDBCPCB_00720 6.3e-291 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MLDBCPCB_00721 4.25e-176 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MLDBCPCB_00722 1.82e-181 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
MLDBCPCB_00723 6.98e-286 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MLDBCPCB_00724 1.39e-231 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MLDBCPCB_00725 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
MLDBCPCB_00726 1.34e-146 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MLDBCPCB_00728 1.83e-59 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MLDBCPCB_00729 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MLDBCPCB_00730 3.11e-106 - - - S ko:K19055 - ko00000,ko01000,ko03016 YbaK proline--tRNA ligase associated domain protein
MLDBCPCB_00731 0.0 - - - E - - - amino acid
MLDBCPCB_00732 0.0 ydaO - - E - - - amino acid
MLDBCPCB_00733 2.63e-53 - - - - - - - -
MLDBCPCB_00734 8.81e-89 - - - K - - - Transcriptional regulator
MLDBCPCB_00735 2.61e-300 - - - EGP - - - Major Facilitator
MLDBCPCB_00736 6.65e-145 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
MLDBCPCB_00737 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
MLDBCPCB_00738 1.73e-148 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
MLDBCPCB_00739 5e-124 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MLDBCPCB_00740 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MLDBCPCB_00741 1.58e-238 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MLDBCPCB_00742 2.11e-66 - - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain protein
MLDBCPCB_00743 1.88e-68 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
MLDBCPCB_00744 1.38e-226 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MLDBCPCB_00745 3.31e-200 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MLDBCPCB_00746 5.93e-237 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
MLDBCPCB_00747 1.79e-214 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
MLDBCPCB_00748 5.04e-175 lutC - - S ko:K00782 - ko00000 LUD domain
MLDBCPCB_00749 0.0 lutB - - C ko:K18929 - ko00000 4Fe-4S dicluster domain
MLDBCPCB_00750 1.43e-208 lutA - - C ko:K18928 - ko00000 Cysteine-rich domain
MLDBCPCB_00751 2.38e-222 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MLDBCPCB_00752 1.56e-276 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
MLDBCPCB_00753 1.27e-40 - - - ET ko:K02030 - ko00000,ko00002,ko02000 PFAM extracellular solute-binding protein, family 3
MLDBCPCB_00754 1.2e-131 - - - ET ko:K02030 - ko00000,ko00002,ko02000 PFAM extracellular solute-binding protein, family 3
MLDBCPCB_00755 2.85e-114 ykhA 3.1.2.20 - I ko:K01073 - ko00000,ko01000 Thioesterase superfamily
MLDBCPCB_00756 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
MLDBCPCB_00757 3.57e-150 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
MLDBCPCB_00758 4.16e-19 - - - - - - - -
MLDBCPCB_00759 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MLDBCPCB_00760 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MLDBCPCB_00761 5.51e-316 steT - - E ko:K03294 - ko00000 amino acid
MLDBCPCB_00762 8.05e-208 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
MLDBCPCB_00763 5.73e-239 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
MLDBCPCB_00764 1.94e-218 whiA - - K ko:K09762 - ko00000 May be required for sporulation
MLDBCPCB_00766 1.83e-21 - - - - - - - -
MLDBCPCB_00767 4.72e-134 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MLDBCPCB_00769 1.31e-243 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MLDBCPCB_00770 1.08e-289 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
MLDBCPCB_00771 1.02e-181 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MLDBCPCB_00772 0.0 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MLDBCPCB_00773 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
MLDBCPCB_00774 2.49e-39 - - - - - - - -
MLDBCPCB_00775 2.08e-208 xylR - - GK - - - ROK family
MLDBCPCB_00776 0.0 xylB 2.7.1.17, 2.7.1.53 - G ko:K00854,ko:K00880 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the FGGY kinase family
MLDBCPCB_00777 3.05e-198 - - - KT ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 YcbB domain
MLDBCPCB_00778 3.21e-244 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MLDBCPCB_00779 3.94e-221 arcC 2.7.2.2 - E ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 ko00000,ko00001,ko01000 Belongs to the carbamate kinase family
MLDBCPCB_00780 1.29e-205 - - - EG - - - EamA-like transporter family
MLDBCPCB_00781 7.03e-134 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
MLDBCPCB_00782 1.6e-82 - - - S - - - Cupredoxin-like domain
MLDBCPCB_00783 2.2e-65 - - - S - - - Cupredoxin-like domain
MLDBCPCB_00784 0.0 copA 3.6.3.3, 3.6.3.5, 3.6.3.54 - P ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
MLDBCPCB_00785 2.05e-109 - - - - - - - -
MLDBCPCB_00787 2.13e-74 - - - - - - - -
MLDBCPCB_00789 1.24e-92 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
MLDBCPCB_00790 1.09e-200 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
MLDBCPCB_00792 9.23e-138 - - - - - - - -
MLDBCPCB_00793 0.0 - - - M - - - domain protein
MLDBCPCB_00794 3.12e-73 - - - - - - - -
MLDBCPCB_00795 9.5e-239 ampC - - V - - - Beta-lactamase
MLDBCPCB_00796 1.25e-304 arcA 3.5.3.6 - E ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 ko00000,ko00001,ko01000 Arginine
MLDBCPCB_00797 1.77e-103 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
MLDBCPCB_00798 0.0 arcD - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
MLDBCPCB_00799 1.97e-297 potE - - U ko:K03756,ko:K03758 - ko00000,ko02000 Amino acid permease
MLDBCPCB_00800 4.87e-173 - - - S ko:K07009 - ko00000 CobB/CobQ-like glutamine amidotransferase domain
MLDBCPCB_00801 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Mur ligase, middle domain
MLDBCPCB_00802 6.8e-140 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
MLDBCPCB_00803 1.73e-248 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MLDBCPCB_00804 1.86e-208 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MLDBCPCB_00805 1.55e-250 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MLDBCPCB_00806 6.33e-294 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MLDBCPCB_00807 6.68e-150 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MLDBCPCB_00808 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MLDBCPCB_00809 6.71e-246 yibE - - S - - - overlaps another CDS with the same product name
MLDBCPCB_00810 4.71e-166 yibF - - S - - - overlaps another CDS with the same product name
MLDBCPCB_00811 2.3e-293 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
MLDBCPCB_00812 4.63e-162 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
MLDBCPCB_00813 1.26e-29 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MLDBCPCB_00814 1.07e-95 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MLDBCPCB_00815 6.84e-121 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MLDBCPCB_00816 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MLDBCPCB_00817 1.3e-212 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MLDBCPCB_00818 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MLDBCPCB_00819 1.05e-88 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
MLDBCPCB_00820 1.76e-45 ywzB - - S - - - Protein of unknown function (DUF1146)
MLDBCPCB_00821 1.05e-308 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MLDBCPCB_00822 2.57e-227 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
MLDBCPCB_00823 4.61e-44 - - - S - - - Protein of unknown function (DUF2969)
MLDBCPCB_00824 3.86e-281 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
MLDBCPCB_00825 1.17e-61 gcsH2 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 glycine cleavage
MLDBCPCB_00826 6.32e-275 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
MLDBCPCB_00827 1.1e-95 - - - - - - - -
MLDBCPCB_00828 8.62e-225 - - - - - - - -
MLDBCPCB_00829 8.36e-233 fecB - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
MLDBCPCB_00830 4.82e-180 fecE 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
MLDBCPCB_00831 4.18e-165 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLDBCPCB_00832 1.79e-101 - - - S - - - Flavodoxin
MLDBCPCB_00833 3.25e-84 moaE 2.8.1.12 - H ko:K03635,ko:K21142 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 MoaE protein
MLDBCPCB_00834 4.04e-48 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 ThiS family
MLDBCPCB_00835 5.25e-279 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 Transporter, major facilitator family protein
MLDBCPCB_00836 3.9e-212 - - - H - - - geranyltranstransferase activity
MLDBCPCB_00837 9.46e-235 - - - - - - - -
MLDBCPCB_00838 3.11e-26 - - - - - - - -
MLDBCPCB_00839 2.22e-151 nreC - - K ko:K07696 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 PFAM regulatory protein LuxR
MLDBCPCB_00840 7.87e-244 nreB 2.7.13.3 - F ko:K07683 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Sensor histidine kinase
MLDBCPCB_00841 1.56e-60 - - - - - - - -
MLDBCPCB_00842 2.03e-136 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
MLDBCPCB_00843 9.66e-110 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
MLDBCPCB_00844 2.19e-291 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 MoeA N-terminal region (domain I and II)
MLDBCPCB_00845 1.65e-107 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
MLDBCPCB_00846 1.35e-238 moeB 2.7.7.80 - H ko:K21029 ko04122,map04122 ko00000,ko00001,ko01000 ThiF family
MLDBCPCB_00847 0.0 narZ 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MLDBCPCB_00848 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
MLDBCPCB_00849 4.22e-130 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase molybdenum cofactor assembly chaperone
MLDBCPCB_00850 9.45e-168 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase
MLDBCPCB_00851 4.67e-298 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MLDBCPCB_00852 7.66e-196 - - - EG - - - EamA-like transporter family
MLDBCPCB_00853 1.15e-152 - - - L - - - Integrase
MLDBCPCB_00854 7.24e-204 rssA - - S - - - Phospholipase, patatin family
MLDBCPCB_00855 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 Levansucrase/Invertase
MLDBCPCB_00856 9.39e-256 xerS - - L - - - Belongs to the 'phage' integrase family
MLDBCPCB_00858 1.76e-94 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MLDBCPCB_00859 2.35e-101 - - - K - - - Transcriptional regulator, MarR family
MLDBCPCB_00860 5.4e-226 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MLDBCPCB_00861 2.51e-47 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
MLDBCPCB_00862 3.95e-203 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
MLDBCPCB_00863 1.05e-167 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
MLDBCPCB_00864 1.21e-286 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MLDBCPCB_00865 6.2e-96 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MLDBCPCB_00866 4.61e-97 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MLDBCPCB_00867 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
MLDBCPCB_00868 2.41e-183 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MLDBCPCB_00869 1.55e-176 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
MLDBCPCB_00870 7.89e-168 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
MLDBCPCB_00879 4.93e-35 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MLDBCPCB_00880 2.94e-239 - - - L - - - PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MLDBCPCB_00881 6.14e-71 - - - - - - - -
MLDBCPCB_00882 3.55e-147 frnE 5.3.4.1 - Q ko:K01829 - ko00000,ko01000 DSBA-like thioredoxin domain
MLDBCPCB_00883 7.05e-101 - - - I - - - alpha/beta hydrolase fold
MLDBCPCB_00884 2.6e-27 - - - K - - - Helix-turn-helix XRE-family like proteins
MLDBCPCB_00885 3.98e-229 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MLDBCPCB_00886 7.37e-275 - 1.5.1.36 - S ko:K19784,ko:K22393,ko:K22394 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
MLDBCPCB_00887 8.9e-131 - 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
MLDBCPCB_00889 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MLDBCPCB_00890 1.34e-232 cytR - - K ko:K02529,ko:K03604 - ko00000,ko03000 Transcriptional regulator, LacI family
MLDBCPCB_00891 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
MLDBCPCB_00892 9.49e-262 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
MLDBCPCB_00893 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
MLDBCPCB_00894 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
MLDBCPCB_00895 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
MLDBCPCB_00896 0.0 - - - M - - - domain protein
MLDBCPCB_00897 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Poly(Glycerol-phosphate) alpha-glucosyltransferase
MLDBCPCB_00898 0.0 tagE6 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
MLDBCPCB_00899 8.53e-95 - - - - - - - -
MLDBCPCB_00900 7.96e-97 - - - K - - - Transcriptional regulator, TetR family
MLDBCPCB_00901 3.25e-18 - - - K - - - Transcriptional regulator, TetR family
MLDBCPCB_00903 1.82e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MLDBCPCB_00904 2.47e-107 - - - - - - - -
MLDBCPCB_00905 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MLDBCPCB_00906 6.39e-234 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MLDBCPCB_00907 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
MLDBCPCB_00908 7.6e-113 - - - S - - - ECF-type riboflavin transporter, S component
MLDBCPCB_00909 0.0 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
MLDBCPCB_00910 1.86e-63 - - - S - - - Cupin 2, conserved barrel domain protein
MLDBCPCB_00911 2.1e-214 - - - C - - - Aldo keto reductase
MLDBCPCB_00912 6.13e-175 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
MLDBCPCB_00913 0.0 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
MLDBCPCB_00914 1.41e-265 - - - P - - - Voltage gated chloride channel
MLDBCPCB_00915 7.94e-290 sptS - - T - - - Histidine kinase
MLDBCPCB_00916 3.15e-153 dltr - - K - - - response regulator
MLDBCPCB_00917 4.14e-111 - - - T - - - Region found in RelA / SpoT proteins
MLDBCPCB_00918 1.17e-91 - - - - - - - -
MLDBCPCB_00919 4.32e-155 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
MLDBCPCB_00920 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
MLDBCPCB_00921 0.0 malT - - G ko:K16211 - ko00000,ko02000 Major Facilitator
MLDBCPCB_00922 1.03e-242 flp - - V - - - Beta-lactamase
MLDBCPCB_00923 7.15e-122 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
MLDBCPCB_00924 5.66e-158 - - - S ko:K07507 - ko00000,ko02000 MgtC family
MLDBCPCB_00925 1.3e-50 - - - S - - - GyrI-like small molecule binding domain
MLDBCPCB_00926 1.08e-89 - - - S - - - GyrI-like small molecule binding domain
MLDBCPCB_00928 1.5e-149 - - - S - - - Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
MLDBCPCB_00929 4.53e-66 azlD - - E - - - Branched-chain amino acid transport
MLDBCPCB_00930 2.19e-153 azlC - - E - - - azaleucine resistance protein AzlC
MLDBCPCB_00931 4.47e-74 - - - K - - - Aminotransferase class I and II
MLDBCPCB_00932 2.19e-193 - - - K - - - Aminotransferase class I and II
MLDBCPCB_00933 0.0 - - - S - - - amidohydrolase
MLDBCPCB_00935 1.65e-206 - - - S - - - reductase
MLDBCPCB_00936 4.4e-114 - 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase, GNAT family
MLDBCPCB_00937 2.44e-147 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MLDBCPCB_00938 7.33e-315 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
MLDBCPCB_00939 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MLDBCPCB_00940 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
MLDBCPCB_00941 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MLDBCPCB_00942 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MLDBCPCB_00943 2.09e-168 jag - - S ko:K06346 - ko00000 R3H domain protein
MLDBCPCB_00944 2.96e-172 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MLDBCPCB_00945 1.39e-76 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MLDBCPCB_00946 7.96e-21 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
MLDBCPCB_00947 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MLDBCPCB_00948 1.41e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MLDBCPCB_00949 1.97e-105 dhrS4 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Oxidoreductase, short chain dehydrogenase reductase family protein
MLDBCPCB_00950 9.78e-14 dhrS4 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Oxidoreductase, short chain dehydrogenase reductase family protein
MLDBCPCB_00951 5.41e-47 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
MLDBCPCB_00952 1.7e-261 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MLDBCPCB_00953 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MLDBCPCB_00954 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MLDBCPCB_00955 4.55e-64 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
MLDBCPCB_00956 5.93e-114 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MLDBCPCB_00957 9.36e-48 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MLDBCPCB_00958 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
MLDBCPCB_00959 1.25e-97 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
MLDBCPCB_00960 6.04e-307 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
MLDBCPCB_00961 1.08e-268 yttB - - EGP - - - Major Facilitator
MLDBCPCB_00962 3.85e-72 - - - - - - - -
MLDBCPCB_00963 1.86e-210 - - - S - - - Polyphosphate nucleotide phosphotransferase, PPK2 family
MLDBCPCB_00964 3.44e-12 - - - K - - - DNA-binding helix-turn-helix protein
MLDBCPCB_00965 2.29e-276 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
MLDBCPCB_00966 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MLDBCPCB_00967 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MLDBCPCB_00968 1.51e-131 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MLDBCPCB_00969 2.86e-244 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MLDBCPCB_00970 1.25e-241 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MLDBCPCB_00971 7.54e-62 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
MLDBCPCB_00972 6.15e-234 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
MLDBCPCB_00973 0.0 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MLDBCPCB_00974 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MLDBCPCB_00975 8.03e-58 yrzL - - S - - - Belongs to the UPF0297 family
MLDBCPCB_00976 3.62e-100 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MLDBCPCB_00977 3.75e-63 yrzB - - S - - - Belongs to the UPF0473 family
MLDBCPCB_00978 8.35e-121 cvpA - - S - - - Colicin V production protein
MLDBCPCB_00979 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MLDBCPCB_00980 2.86e-72 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
MLDBCPCB_00981 1.01e-124 yslB - - S - - - Protein of unknown function (DUF2507)
MLDBCPCB_00982 2.58e-184 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
MLDBCPCB_00983 3.33e-133 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MLDBCPCB_00984 4e-121 - - - S ko:K07095 - ko00000 Phosphoesterase
MLDBCPCB_00985 3.62e-100 ykuL - - S - - - (CBS) domain
MLDBCPCB_00986 1.1e-195 - - - S - - - haloacid dehalogenase-like hydrolase
MLDBCPCB_00987 6.23e-188 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
MLDBCPCB_00988 8.88e-71 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MLDBCPCB_00989 1.84e-75 - - - - - - - -
MLDBCPCB_00990 2.54e-268 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
MLDBCPCB_00991 1.63e-233 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
MLDBCPCB_00992 1.15e-178 - - - - - - - -
MLDBCPCB_00993 1.22e-168 yebC - - K - - - Transcriptional regulatory protein
MLDBCPCB_00994 1.1e-230 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
MLDBCPCB_00995 2.49e-232 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
MLDBCPCB_00996 6.31e-62 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
MLDBCPCB_00997 1.01e-100 - - - NU ko:K02246 - ko00000,ko00002,ko02044 general secretion pathway protein
MLDBCPCB_00998 1.61e-54 - - - - - - - -
MLDBCPCB_00999 9.32e-92 - - - - ko:K02248 - ko00000,ko00002,ko02044 -
MLDBCPCB_01001 2.07e-185 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
MLDBCPCB_01002 4.18e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MLDBCPCB_01003 1.08e-146 - - - S - - - Calcineurin-like phosphoesterase
MLDBCPCB_01004 9.28e-121 yutD - - S - - - Protein of unknown function (DUF1027)
MLDBCPCB_01005 2.87e-171 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MLDBCPCB_01006 8.48e-135 - - - S - - - Protein of unknown function (DUF1461)
MLDBCPCB_01007 1.83e-149 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
MLDBCPCB_01008 6.14e-207 - - - - - - - -
MLDBCPCB_01009 1.92e-202 - - - G - - - Xylose isomerase domain protein TIM barrel
MLDBCPCB_01010 1.32e-236 XK27_12525 - - S - - - AI-2E family transporter
MLDBCPCB_01011 7.74e-173 XK27_07210 - - S - - - B3 4 domain
MLDBCPCB_01012 1.36e-101 yybA - - K - - - Transcriptional regulator
MLDBCPCB_01013 5.25e-118 - - - K - - - Domain of unknown function (DUF1836)
MLDBCPCB_01014 7.44e-113 - - - GM - - - epimerase
MLDBCPCB_01015 1.39e-198 - - - V - - - (ABC) transporter
MLDBCPCB_01016 1.67e-307 yhdP - - S - - - Transporter associated domain
MLDBCPCB_01017 1.98e-110 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
MLDBCPCB_01018 3.68e-97 - - - S ko:K04750 - ko00000 3-demethylubiquinone-9 3-methyltransferase
MLDBCPCB_01019 2.64e-246 yycB - - P ko:K03449 - ko00000,ko02000 Transporter, major facilitator family protein
MLDBCPCB_01020 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MLDBCPCB_01021 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MLDBCPCB_01022 1.16e-51 - - - - - - - -
MLDBCPCB_01023 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
MLDBCPCB_01024 1.61e-50 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
MLDBCPCB_01025 5.01e-13 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
MLDBCPCB_01026 2.32e-104 usp5 - - T - - - universal stress protein
MLDBCPCB_01027 1.39e-106 - - - K ko:K03719 - ko00000,ko03000,ko03036 AsnC family
MLDBCPCB_01028 3.7e-297 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MLDBCPCB_01029 1.27e-133 apl 3.1.3.1 - S ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 SNARE associated Golgi protein
MLDBCPCB_01030 1.97e-231 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
MLDBCPCB_01031 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
MLDBCPCB_01032 8.5e-287 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MLDBCPCB_01033 1.34e-234 celE3 - - E - - - GDSL-like Lipase/Acylhydrolase family
MLDBCPCB_01034 6.01e-103 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
MLDBCPCB_01035 8.54e-72 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
MLDBCPCB_01036 5.55e-121 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
MLDBCPCB_01037 1.21e-48 - - - - - - - -
MLDBCPCB_01038 1.24e-68 - - - - - - - -
MLDBCPCB_01039 2.24e-261 - - - - - - - -
MLDBCPCB_01040 6.73e-107 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MLDBCPCB_01041 9.74e-176 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
MLDBCPCB_01042 7.23e-202 yvgN - - S - - - Aldo keto reductase
MLDBCPCB_01043 5.06e-160 XK27_10500 - - K - - - response regulator
MLDBCPCB_01044 7.16e-232 kinG - - T - - - Histidine kinase-like ATPases
MLDBCPCB_01045 4.29e-175 XK27_05695 - - V ko:K02003,ko:K19083 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MLDBCPCB_01046 2.38e-164 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
MLDBCPCB_01047 1.62e-242 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
MLDBCPCB_01048 4.9e-202 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
MLDBCPCB_01049 3.74e-213 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
MLDBCPCB_01050 5.36e-27 - - - K - - - helix_turn_helix, mercury resistance
MLDBCPCB_01052 6.56e-252 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
MLDBCPCB_01053 8.5e-208 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
MLDBCPCB_01054 1.53e-123 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MLDBCPCB_01055 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
MLDBCPCB_01056 4.47e-16 - - - S - - - Protein of unknown function (DUF4044)
MLDBCPCB_01057 9.07e-73 - - - - - - - -
MLDBCPCB_01058 1.5e-101 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
MLDBCPCB_01059 9.31e-224 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MLDBCPCB_01060 3.47e-73 ftsL - - D - - - Cell division protein FtsL
MLDBCPCB_01061 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
MLDBCPCB_01062 7.73e-230 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MLDBCPCB_01063 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MLDBCPCB_01064 1.45e-260 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MLDBCPCB_01065 3.54e-194 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MLDBCPCB_01066 0.0 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MLDBCPCB_01067 6.52e-289 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MLDBCPCB_01068 1.11e-92 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MLDBCPCB_01069 3.2e-54 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
MLDBCPCB_01070 1.97e-185 ylmH - - S - - - S4 domain protein
MLDBCPCB_01071 3.71e-109 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
MLDBCPCB_01072 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MLDBCPCB_01073 5.69e-44 cspB - - K ko:K03704 - ko00000,ko03000 Cold shock protein
MLDBCPCB_01074 2.48e-129 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
MLDBCPCB_01075 1.54e-33 - - - - - - - -
MLDBCPCB_01076 3.4e-162 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MLDBCPCB_01077 1.75e-275 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
MLDBCPCB_01078 1.13e-75 XK27_04120 - - S - - - Putative amino acid metabolism
MLDBCPCB_01079 2.15e-286 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MLDBCPCB_01080 9.47e-158 pgm6 - - G - - - phosphoglycerate mutase
MLDBCPCB_01081 3.82e-157 - - - S - - - repeat protein
MLDBCPCB_01082 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MLDBCPCB_01083 8.58e-223 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MLDBCPCB_01084 2.69e-165 - - - M - - - PFAM NLP P60 protein
MLDBCPCB_01085 3.16e-233 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
MLDBCPCB_01086 1.18e-196 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MLDBCPCB_01087 5.63e-177 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MLDBCPCB_01088 3.2e-118 - - - P - - - Cadmium resistance transporter
MLDBCPCB_01089 1.14e-74 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
MLDBCPCB_01090 4.25e-44 - - - M - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MLDBCPCB_01091 7.25e-301 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
MLDBCPCB_01092 4.38e-72 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
MLDBCPCB_01093 3.78e-169 yceF - - P ko:K05794 - ko00000 membrane
MLDBCPCB_01094 8.16e-212 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
MLDBCPCB_01095 2.35e-215 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
MLDBCPCB_01096 0.0 - - - L - - - Transposase
MLDBCPCB_01097 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MLDBCPCB_01098 4.79e-307 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
MLDBCPCB_01099 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
MLDBCPCB_01100 9.8e-305 - - - S - - - C4-dicarboxylate anaerobic carrier
MLDBCPCB_01101 3.39e-33 - - - S - - - C4-dicarboxylate anaerobic carrier
MLDBCPCB_01102 3.18e-160 pgm3 - - G - - - phosphoglycerate mutase family
MLDBCPCB_01103 1.77e-56 - - - - - - - -
MLDBCPCB_01104 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MLDBCPCB_01105 2.84e-264 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 dehydrogenase
MLDBCPCB_01106 2.56e-188 - - - S - - - Alpha beta hydrolase
MLDBCPCB_01107 1.02e-279 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MLDBCPCB_01108 1.93e-131 - - - - - - - -
MLDBCPCB_01110 5.09e-162 - - - M - - - ErfK YbiS YcfS YnhG
MLDBCPCB_01111 7.67e-252 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MLDBCPCB_01112 1.13e-289 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
MLDBCPCB_01113 1.16e-133 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MLDBCPCB_01114 2.06e-197 - - - S - - - Helix-turn-helix domain
MLDBCPCB_01115 0.0 ymfH - - S - - - Peptidase M16
MLDBCPCB_01116 2.13e-294 ymfF - - S - - - Peptidase M16 inactive domain protein
MLDBCPCB_01117 4.04e-205 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
MLDBCPCB_01118 2.06e-151 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MLDBCPCB_01119 4.45e-141 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
MLDBCPCB_01120 1.62e-118 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
MLDBCPCB_01121 4.46e-194 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
MLDBCPCB_01122 8.33e-230 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
MLDBCPCB_01123 6.98e-156 radC - - L ko:K03630 - ko00000 DNA repair protein
MLDBCPCB_01124 1.23e-311 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
MLDBCPCB_01125 1.22e-292 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
MLDBCPCB_01126 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MLDBCPCB_01127 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
MLDBCPCB_01128 6.92e-236 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
MLDBCPCB_01129 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
MLDBCPCB_01130 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MLDBCPCB_01131 5.83e-292 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MLDBCPCB_01132 2.48e-274 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
MLDBCPCB_01133 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MLDBCPCB_01134 5.96e-139 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MLDBCPCB_01135 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
MLDBCPCB_01136 6.42e-140 maa3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
MLDBCPCB_01137 2.71e-200 - - - U ko:K05340 - ko00000,ko02000 sugar transport
MLDBCPCB_01138 0.0 yclK - - T - - - Histidine kinase
MLDBCPCB_01139 2.7e-172 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
MLDBCPCB_01141 2.2e-110 lytE - - M - - - Lysin motif
MLDBCPCB_01142 4.01e-193 - - - S - - - Cof-like hydrolase
MLDBCPCB_01143 3.7e-106 - - - K - - - Transcriptional regulator
MLDBCPCB_01144 0.0 oatA - - I - - - Acyltransferase
MLDBCPCB_01145 5.17e-70 - - - - - - - -
MLDBCPCB_01146 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MLDBCPCB_01147 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MLDBCPCB_01148 7.48e-165 ybbR - - S - - - YbbR-like protein
MLDBCPCB_01149 6.61e-195 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MLDBCPCB_01150 0.0 fucP - - G ko:K02429 - ko00000,ko02000 Major Facilitator Superfamily
MLDBCPCB_01151 1.43e-87 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MLDBCPCB_01152 1.31e-213 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MLDBCPCB_01153 6.77e-216 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
MLDBCPCB_01154 3.7e-133 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
MLDBCPCB_01155 3.55e-99 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
MLDBCPCB_01156 1.46e-112 - - - K - - - Acetyltransferase (GNAT) domain
MLDBCPCB_01157 6.95e-105 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
MLDBCPCB_01158 1.38e-228 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
MLDBCPCB_01159 1.84e-174 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MLDBCPCB_01160 9.61e-137 - - - - - - - -
MLDBCPCB_01161 3.15e-108 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MLDBCPCB_01162 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MLDBCPCB_01163 3.29e-187 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Serine aminopeptidase, S33
MLDBCPCB_01164 1.43e-47 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
MLDBCPCB_01165 2.46e-72 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MLDBCPCB_01166 3.6e-107 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MLDBCPCB_01167 1.79e-267 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MLDBCPCB_01168 1.33e-313 - - - M - - - Glycosyl transferase family group 2
MLDBCPCB_01170 1.86e-288 aadAT - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 Aminotransferase, class I
MLDBCPCB_01171 8.31e-158 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MLDBCPCB_01172 1.39e-92 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MLDBCPCB_01173 1.1e-126 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
MLDBCPCB_01174 2.9e-31 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MLDBCPCB_01175 9.18e-31 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
MLDBCPCB_01176 1.05e-174 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MLDBCPCB_01177 3.58e-93 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MLDBCPCB_01178 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
MLDBCPCB_01179 5.12e-266 yacL - - S - - - domain protein
MLDBCPCB_01180 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MLDBCPCB_01181 1.1e-125 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
MLDBCPCB_01182 3.33e-66 yjdJ - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
MLDBCPCB_01183 2.5e-162 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MLDBCPCB_01184 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
MLDBCPCB_01185 3.51e-180 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
MLDBCPCB_01186 5.84e-172 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MLDBCPCB_01187 9.62e-154 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MLDBCPCB_01188 2.47e-273 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
MLDBCPCB_01189 6.27e-216 - - - I - - - alpha/beta hydrolase fold
MLDBCPCB_01190 3.04e-172 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MLDBCPCB_01191 0.0 - - - S - - - Bacterial membrane protein, YfhO
MLDBCPCB_01192 6.41e-236 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
MLDBCPCB_01193 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
MLDBCPCB_01194 4.05e-70 - - - S - - - branched-chain amino acid
MLDBCPCB_01195 4.95e-195 - - - E - - - AzlC protein
MLDBCPCB_01196 2.23e-260 hpk31 - - T - - - Histidine kinase
MLDBCPCB_01197 3.27e-159 vanR - - K - - - response regulator
MLDBCPCB_01198 8.13e-263 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MLDBCPCB_01199 1.32e-219 deoR - - K ko:K05346 - ko00000,ko03000 sugar-binding domain protein
MLDBCPCB_01200 3.27e-167 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
MLDBCPCB_01201 2.15e-298 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 pyrimidine-nucleoside phosphorylase
MLDBCPCB_01202 1.09e-296 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
MLDBCPCB_01203 9.74e-154 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MLDBCPCB_01204 4.25e-173 - - - S - - - Protein of unknown function (DUF1129)
MLDBCPCB_01205 6.1e-255 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MLDBCPCB_01206 5.8e-43 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
MLDBCPCB_01207 4.83e-198 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
MLDBCPCB_01208 2.79e-178 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
MLDBCPCB_01209 3.73e-200 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
MLDBCPCB_01210 6.29e-163 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
MLDBCPCB_01211 5.97e-208 - 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 3-hydroxyacyl-CoA dehydrogenase
MLDBCPCB_01212 2.76e-217 rihA 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
MLDBCPCB_01213 3.42e-278 nupG - - F ko:K03317,ko:K11535,ko:K16323 - ko00000,ko02000 Nucleoside transporter
MLDBCPCB_01214 1.77e-285 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
MLDBCPCB_01215 5.67e-178 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MLDBCPCB_01216 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MLDBCPCB_01217 0.0 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MLDBCPCB_01218 7.01e-109 - - - - - - - -
MLDBCPCB_01219 0.0 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
MLDBCPCB_01220 5.28e-181 - - - T - - - EAL domain
MLDBCPCB_01221 4.18e-168 - - - F - - - glutamine amidotransferase
MLDBCPCB_01222 1.74e-85 - - - - - - - -
MLDBCPCB_01223 2.22e-145 - - - GM - - - NAD(P)H-binding
MLDBCPCB_01224 3.43e-110 - - - S - - - membrane
MLDBCPCB_01225 1.28e-105 - - - S - - - membrane
MLDBCPCB_01226 6.78e-136 - - - K - - - Transcriptional regulator C-terminal region
MLDBCPCB_01227 7.26e-208 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
MLDBCPCB_01228 3.02e-52 - - - K - - - Transcriptional regulator
MLDBCPCB_01229 5.61e-75 - - - K - - - Transcriptional regulator
MLDBCPCB_01230 5.69e-235 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase, type I
MLDBCPCB_01231 1.45e-214 ypuA - - S - - - Protein of unknown function (DUF1002)
MLDBCPCB_01232 1.39e-83 - - - GM - - - NAD(P)H-binding
MLDBCPCB_01233 1.02e-120 - - - K - - - Virulence activator alpha C-term
MLDBCPCB_01234 2.49e-120 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
MLDBCPCB_01235 2.05e-195 - - - S - - - Alpha beta hydrolase
MLDBCPCB_01236 8.09e-44 - - - S ko:K06889 - ko00000 thiolester hydrolase activity
MLDBCPCB_01237 7.41e-114 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
MLDBCPCB_01238 2.15e-203 lysR - - K - - - Transcriptional regulator
MLDBCPCB_01239 7.89e-39 - - - C - - - Flavodoxin
MLDBCPCB_01240 1.38e-29 - - - C - - - Flavodoxin
MLDBCPCB_01241 1.94e-211 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 Oxidoreductase, aldo keto reductase family protein
MLDBCPCB_01242 2.32e-210 - - - K - - - COG COG0846 NAD-dependent protein deacetylases, SIR2 family
MLDBCPCB_01243 4.09e-99 - - - K - - - NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MLDBCPCB_01244 1.45e-98 - - - K - - - Bacterial regulatory proteins, tetR family
MLDBCPCB_01245 1.16e-72 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 decarboxylase
MLDBCPCB_01246 3.01e-92 - - - P - - - FAD-binding domain
MLDBCPCB_01247 2.28e-139 - - - S - - - Peptidase propeptide and YPEB domain
MLDBCPCB_01248 1.66e-303 - - - T - - - GHKL domain
MLDBCPCB_01249 2.05e-156 - - - T - - - Transcriptional regulatory protein, C terminal
MLDBCPCB_01250 8.92e-21 rmaD - - K - - - transcriptional
MLDBCPCB_01251 5.55e-60 - - - S - - - Bacteriophage holin family
MLDBCPCB_01252 3.47e-174 - - - M - - - Glycosyl hydrolases family 25
MLDBCPCB_01253 3.95e-31 - - - - - - - -
MLDBCPCB_01254 0.0 - - - L - - - Recombinase zinc beta ribbon domain
MLDBCPCB_01255 0.0 - - - L - - - Recombinase
MLDBCPCB_01257 0.0 - - - L - - - Helicase C-terminal domain protein
MLDBCPCB_01258 3.96e-61 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
MLDBCPCB_01259 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MLDBCPCB_01260 5.06e-237 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
MLDBCPCB_01261 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MLDBCPCB_01262 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MLDBCPCB_01263 1.36e-66 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MLDBCPCB_01264 1.11e-260 camS - - S - - - sex pheromone
MLDBCPCB_01265 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MLDBCPCB_01266 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
MLDBCPCB_01267 8.91e-270 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MLDBCPCB_01268 3.91e-130 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MLDBCPCB_01269 3.07e-149 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
MLDBCPCB_01270 6.34e-180 budC 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 reductase
MLDBCPCB_01272 2.46e-288 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
MLDBCPCB_01273 6.2e-271 npp - - S - - - type I phosphodiesterase nucleotide pyrophosphatase
MLDBCPCB_01274 9.08e-317 - - - E ko:K03294 - ko00000 amino acid
MLDBCPCB_01275 1.63e-233 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MLDBCPCB_01277 1.12e-268 - 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
MLDBCPCB_01278 4.51e-54 - - - S - - - Cytochrome B5
MLDBCPCB_01279 8.47e-08 - - - S - - - Cytochrome B5
MLDBCPCB_01280 2.3e-52 - - - S - - - Cytochrome B5
MLDBCPCB_01281 5.36e-92 - - - S ko:K02348 - ko00000 Gnat family
MLDBCPCB_01282 7.48e-155 - - - GM - - - NmrA-like family
MLDBCPCB_01283 2.74e-69 ydeP - - K - - - Transcriptional regulator, HxlR family
MLDBCPCB_01284 3.2e-138 XK27_02070 - - S ko:K07078 - ko00000 Nitroreductase family
MLDBCPCB_01285 9.01e-57 - - - K - - - Transcriptional regulator, HxlR family
MLDBCPCB_01286 2.59e-34 - - - K - - - Transcriptional regulator, HxlR family
MLDBCPCB_01287 7.97e-292 - - - - - - - -
MLDBCPCB_01288 7.6e-269 - - - EGP - - - Major Facilitator Superfamily
MLDBCPCB_01289 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
MLDBCPCB_01290 7.17e-146 - - - GM - - - NAD dependent epimerase dehydratase family protein
MLDBCPCB_01291 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
MLDBCPCB_01292 5.35e-121 - - - S - - - ECF transporter, substrate-specific component
MLDBCPCB_01293 1.43e-252 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
MLDBCPCB_01294 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
MLDBCPCB_01295 6.11e-158 - - - T - - - Putative diguanylate phosphodiesterase
MLDBCPCB_01296 2.35e-83 - 2.7.7.65 - T ko:K02488 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko00002,ko01000,ko02022 GGDEF domain
MLDBCPCB_01298 2.94e-65 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MLDBCPCB_01299 2.79e-75 XK27_06915 - - K ko:K10947 - ko00000,ko03000 transcriptional regulator PadR family
MLDBCPCB_01300 8.01e-129 - - - S - - - Protein of unknown function (DUF1700)
MLDBCPCB_01301 3.1e-168 - - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
MLDBCPCB_01302 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
MLDBCPCB_01303 4.63e-255 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MLDBCPCB_01304 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MLDBCPCB_01305 9.33e-48 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
MLDBCPCB_01306 6.21e-119 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MLDBCPCB_01307 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MLDBCPCB_01308 5.87e-62 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MLDBCPCB_01309 2.01e-141 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MLDBCPCB_01310 2.71e-51 - - - S - - - Protein of unknown function (DUF2508)
MLDBCPCB_01311 2.14e-147 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MLDBCPCB_01312 2.83e-69 yaaQ - - S - - - Cyclic-di-AMP receptor
MLDBCPCB_01313 1.29e-235 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
MLDBCPCB_01314 3.71e-76 yabA - - L - - - Involved in initiation control of chromosome replication
MLDBCPCB_01315 3.7e-199 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MLDBCPCB_01316 6.09e-176 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
MLDBCPCB_01317 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
MLDBCPCB_01318 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MLDBCPCB_01319 1.87e-221 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
MLDBCPCB_01320 6.02e-247 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
MLDBCPCB_01321 2.5e-171 - - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C-terminal domain protein
MLDBCPCB_01322 8.12e-204 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
MLDBCPCB_01323 1.31e-193 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
MLDBCPCB_01324 5.82e-194 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
MLDBCPCB_01325 7.41e-176 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MLDBCPCB_01326 1.43e-160 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
MLDBCPCB_01327 2.47e-192 - - - - - - - -
MLDBCPCB_01328 3.82e-310 - - - M - - - Glycosyl transferase
MLDBCPCB_01329 8.68e-278 - - - G - - - Glycosyl hydrolases family 8
MLDBCPCB_01330 4.88e-92 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
MLDBCPCB_01331 1.3e-57 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
MLDBCPCB_01332 0.0 mycA 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
MLDBCPCB_01333 3.91e-304 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
MLDBCPCB_01334 2.8e-152 ktrA - - P ko:K03499 - ko00000,ko02000 domain protein
MLDBCPCB_01335 2.66e-114 - - - Q - - - Methyltransferase
MLDBCPCB_01336 2.11e-290 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
MLDBCPCB_01337 2.81e-230 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
MLDBCPCB_01338 3.09e-215 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
MLDBCPCB_01339 7.45e-122 - - - S - - - NADPH-dependent FMN reductase
MLDBCPCB_01340 2.89e-230 - - - S - - - Conserved hypothetical protein 698
MLDBCPCB_01341 5.26e-174 - - - I - - - alpha/beta hydrolase fold
MLDBCPCB_01342 9.73e-215 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
MLDBCPCB_01343 4.92e-305 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MLDBCPCB_01344 1.17e-230 - - - - - - - -
MLDBCPCB_01345 5.27e-169 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MLDBCPCB_01346 4.57e-307 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
MLDBCPCB_01347 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
MLDBCPCB_01348 8.26e-136 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MLDBCPCB_01349 5.37e-248 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
MLDBCPCB_01350 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MLDBCPCB_01351 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MLDBCPCB_01352 1.15e-162 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MLDBCPCB_01353 2.23e-50 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MLDBCPCB_01354 7.43e-170 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
MLDBCPCB_01355 0.0 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MLDBCPCB_01356 1.61e-271 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MLDBCPCB_01357 3e-108 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MLDBCPCB_01358 9.77e-170 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Belongs to the alpha-acetolactate decarboxylase family
MLDBCPCB_01359 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
MLDBCPCB_01360 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
MLDBCPCB_01361 6.76e-227 ydbI - - K - - - AI-2E family transporter
MLDBCPCB_01362 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MLDBCPCB_01363 7.33e-253 - - - EGP - - - Major Facilitator
MLDBCPCB_01364 2.18e-115 ymdB - - S - - - Macro domain protein
MLDBCPCB_01365 2.13e-142 - - - K - - - Helix-turn-helix domain
MLDBCPCB_01366 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
MLDBCPCB_01367 1.66e-61 - - - - - - - -
MLDBCPCB_01368 1.32e-307 - - - S - - - Putative metallopeptidase domain
MLDBCPCB_01369 1.46e-261 - - - S - - - associated with various cellular activities
MLDBCPCB_01370 1.92e-153 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
MLDBCPCB_01371 3.47e-85 yeaO - - S - - - Protein of unknown function, DUF488
MLDBCPCB_01373 3.23e-149 yrkL - - S - - - Flavodoxin-like fold
MLDBCPCB_01374 2.84e-73 - - - - - - - -
MLDBCPCB_01376 1.97e-131 - - - S - - - PD-(D/E)XK nuclease family transposase
MLDBCPCB_01377 1.62e-34 - - - S - - - PD-(D/E)XK nuclease family transposase
MLDBCPCB_01378 5.87e-65 - - - - - - - -
MLDBCPCB_01379 5.28e-262 yngD - - S ko:K07097 - ko00000 DHHA1 domain
MLDBCPCB_01380 6.07e-292 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
MLDBCPCB_01381 1.8e-316 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
MLDBCPCB_01382 5.99e-137 - - - NU - - - mannosyl-glycoprotein
MLDBCPCB_01383 8.04e-184 - - - S - - - Putative ABC-transporter type IV
MLDBCPCB_01384 0.0 - - - S - - - ABC transporter, ATP-binding protein
MLDBCPCB_01385 5.56e-25 - - - - - - - -
MLDBCPCB_01386 6.86e-98 - - - O - - - OsmC-like protein
MLDBCPCB_01387 5.85e-65 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MLDBCPCB_01388 1.12e-78 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MLDBCPCB_01389 7.97e-273 - - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MLDBCPCB_01390 2.49e-43 - - - - - - - -
MLDBCPCB_01391 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 associated with various cellular activities
MLDBCPCB_01393 1.12e-135 - - - K - - - PFAM GCN5-related N-acetyltransferase
MLDBCPCB_01394 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MLDBCPCB_01395 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
MLDBCPCB_01396 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
MLDBCPCB_01397 5.18e-222 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
MLDBCPCB_01398 7.36e-272 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
MLDBCPCB_01399 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MLDBCPCB_01400 1.89e-80 - - - - - - - -
MLDBCPCB_01401 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
MLDBCPCB_01402 7.01e-244 - - - E - - - Zinc-binding dehydrogenase
MLDBCPCB_01403 2.72e-113 - - - K - - - transcriptional regulator (TetR family)
MLDBCPCB_01404 2.39e-234 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
MLDBCPCB_01405 4.22e-148 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MLDBCPCB_01406 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MLDBCPCB_01407 1.18e-50 - - - - - - - -
MLDBCPCB_01408 4.57e-65 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
MLDBCPCB_01409 7.15e-315 - 3.2.1.17 CBM50 NU ko:K01185,ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MLDBCPCB_01410 3.11e-220 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
MLDBCPCB_01411 2.14e-32 - - - - - - - -
MLDBCPCB_01412 1.03e-146 - - - - - - - -
MLDBCPCB_01413 4.99e-273 yttB - - EGP - - - Major Facilitator
MLDBCPCB_01414 6.55e-310 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
MLDBCPCB_01415 2.46e-113 - - - - - - - -
MLDBCPCB_01416 2.49e-141 nnrE 5.1.99.6 - H ko:K17759 - ko00000,ko01000 Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
MLDBCPCB_01417 0.0 - - - S - - - Putative peptidoglycan binding domain
MLDBCPCB_01419 2.12e-285 - - - L ko:K07484 - ko00000 Transposase IS66 family
MLDBCPCB_01421 2.09e-115 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MLDBCPCB_01422 4.95e-86 - - - K - - - HxlR-like helix-turn-helix
MLDBCPCB_01423 3.88e-71 - - - S - - - macrophage migration inhibitory factor
MLDBCPCB_01424 2.89e-68 - - - C - - - Oxidoreductase
MLDBCPCB_01425 3.41e-27 - - - C - - - Oxidoreductase
MLDBCPCB_01426 9.11e-114 - - - C - - - Oxidoreductase
MLDBCPCB_01429 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
MLDBCPCB_01430 1.85e-202 - - - S - - - Calcineurin-like phosphoesterase
MLDBCPCB_01433 1.55e-143 - - - - - - - -
MLDBCPCB_01434 0.0 - - - EGP - - - Major Facilitator
MLDBCPCB_01435 0.0 - - - P ko:K07085 - ko00000 Predicted Permease Membrane Region
MLDBCPCB_01436 1.1e-171 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
MLDBCPCB_01437 3.54e-165 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
MLDBCPCB_01438 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MLDBCPCB_01439 5.27e-197 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MLDBCPCB_01440 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
MLDBCPCB_01441 5.75e-112 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
MLDBCPCB_01443 0.0 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
MLDBCPCB_01444 8.18e-174 - - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
MLDBCPCB_01445 4.16e-180 - - - S - - - Membrane
MLDBCPCB_01446 2e-98 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase
MLDBCPCB_01447 9.79e-29 - - - - - - - -
MLDBCPCB_01448 2.03e-111 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
MLDBCPCB_01449 1.88e-309 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
MLDBCPCB_01450 3.61e-61 - - - - - - - -
MLDBCPCB_01451 1.95e-109 uspA - - T - - - universal stress protein
MLDBCPCB_01452 8.8e-264 araR - - K ko:K02103 - ko00000,ko03000 Transcriptional regulator
MLDBCPCB_01453 3.44e-200 yvgN - - S - - - Aldo keto reductase
MLDBCPCB_01454 3.47e-123 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
MLDBCPCB_01455 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
MLDBCPCB_01456 1.91e-178 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
MLDBCPCB_01457 0.0 araB 2.7.1.16 - G ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 carbohydrate kinase FGGY
MLDBCPCB_01458 0.0 araP - - U - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MLDBCPCB_01459 6.98e-137 - - - L - - - Helix-turn-helix domain
MLDBCPCB_01460 2.48e-178 - - - L ko:K07497 - ko00000 hmm pf00665
MLDBCPCB_01461 5.21e-191 - - - K - - - Helix-turn-helix XRE-family like proteins
MLDBCPCB_01462 1.28e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
MLDBCPCB_01463 5.45e-153 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MLDBCPCB_01464 6.64e-139 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
MLDBCPCB_01465 3.61e-61 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MLDBCPCB_01466 1.16e-203 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MLDBCPCB_01467 5.72e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MLDBCPCB_01468 8.8e-70 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MLDBCPCB_01469 9.81e-157 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MLDBCPCB_01470 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MLDBCPCB_01471 5.49e-38 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
MLDBCPCB_01472 1.1e-55 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MLDBCPCB_01473 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MLDBCPCB_01474 2.58e-65 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MLDBCPCB_01475 7.42e-125 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MLDBCPCB_01476 1.54e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MLDBCPCB_01477 1.06e-123 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MLDBCPCB_01478 5.03e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MLDBCPCB_01479 5.95e-112 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MLDBCPCB_01480 5.94e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
MLDBCPCB_01481 6.05e-93 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
MLDBCPCB_01482 2.88e-306 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MLDBCPCB_01483 4.52e-161 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MLDBCPCB_01484 9.82e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MLDBCPCB_01485 5.79e-21 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
MLDBCPCB_01486 1.54e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MLDBCPCB_01487 1.62e-83 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MLDBCPCB_01488 8.91e-220 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MLDBCPCB_01489 8.08e-83 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
MLDBCPCB_01490 7.08e-186 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MLDBCPCB_01491 9.73e-195 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MLDBCPCB_01492 1.43e-181 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MLDBCPCB_01493 6.12e-182 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MLDBCPCB_01494 9.25e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MLDBCPCB_01495 3.94e-85 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
MLDBCPCB_01496 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
MLDBCPCB_01497 2.63e-264 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MLDBCPCB_01498 2.71e-186 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
MLDBCPCB_01499 0.0 snf - - KL - - - domain protein
MLDBCPCB_01501 2.74e-50 - - - - ko:K18829 - ko00000,ko02048 -
MLDBCPCB_01502 1.71e-87 - - - T ko:K07171 - ko00000,ko01000,ko02048 Toxin-antitoxin system, toxin component, MazF family
MLDBCPCB_01503 5.64e-241 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
MLDBCPCB_01504 9.87e-202 - - - L - - - Integrase core domain
MLDBCPCB_01505 2.9e-170 - - - O - - - Bacterial dnaA protein
MLDBCPCB_01506 4.51e-254 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MLDBCPCB_01508 2.82e-261 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
MLDBCPCB_01509 1.05e-224 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MLDBCPCB_01510 9.02e-201 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
MLDBCPCB_01511 2.6e-167 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MLDBCPCB_01512 3.65e-291 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
MLDBCPCB_01513 9.61e-213 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
MLDBCPCB_01514 2.48e-57 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MLDBCPCB_01517 4.32e-155 sdhB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
MLDBCPCB_01518 5.11e-188 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
MLDBCPCB_01519 6.57e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Peroxiredoxin
MLDBCPCB_01520 0.0 - 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Thioredoxin domain
MLDBCPCB_01521 2.89e-224 - - - M - - - LPXTG-motif cell wall anchor domain protein
MLDBCPCB_01522 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
MLDBCPCB_01523 2.75e-41 - - - M - - - LPXTG-motif cell wall anchor domain protein
MLDBCPCB_01525 3.38e-159 - - - - - - - -
MLDBCPCB_01526 2.84e-73 - - - S - - - Sugar efflux transporter for intercellular exchange
MLDBCPCB_01527 0.0 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
MLDBCPCB_01529 0.0 - - - L - - - Helicase C-terminal domain protein
MLDBCPCB_01530 2.72e-102 - 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 PAP2 superfamily
MLDBCPCB_01531 4.45e-226 ydhF - - S - - - Aldo keto reductase
MLDBCPCB_01533 8.69e-182 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MLDBCPCB_01534 1.26e-82 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
MLDBCPCB_01535 2.9e-57 - - - S ko:K07002 - ko00000 Serine hydrolase
MLDBCPCB_01537 3.03e-232 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MLDBCPCB_01538 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
MLDBCPCB_01539 2.3e-52 - - - S - - - Cytochrome b5-like Heme/Steroid binding domain
MLDBCPCB_01540 1.63e-148 - - - S ko:K07118 - ko00000 NAD(P)H-binding
MLDBCPCB_01541 3.88e-50 - - - - - - - -
MLDBCPCB_01542 3.5e-167 - - - IQ - - - dehydrogenase reductase
MLDBCPCB_01543 2.03e-307 - - - EGP - - - MFS transporter, metabolite H symporter (MHS) family protein
MLDBCPCB_01545 0.0 cadA - - P - - - P-type ATPase
MLDBCPCB_01546 5.23e-276 - 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Metalloenzyme superfamily
MLDBCPCB_01547 4.44e-11 - - - - - - - -
MLDBCPCB_01548 1.83e-197 - - - GM - - - NAD(P)H-binding
MLDBCPCB_01549 3.87e-97 ywnA - - K - - - Transcriptional regulator
MLDBCPCB_01550 1.77e-207 proWY - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, QAT family
MLDBCPCB_01551 2.35e-139 proWZ - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MLDBCPCB_01552 1.01e-180 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MLDBCPCB_01553 1.96e-138 - - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, permease protein
MLDBCPCB_01554 3.53e-100 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
MLDBCPCB_01555 0.0 eriC - - P ko:K03281 - ko00000 chloride
MLDBCPCB_01556 1.96e-275 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
MLDBCPCB_01557 5.25e-140 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MLDBCPCB_01558 4.92e-244 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MLDBCPCB_01559 2.06e-198 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
MLDBCPCB_01560 2.09e-216 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
MLDBCPCB_01564 1.21e-247 gtf2 - - M - - - A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
MLDBCPCB_01565 1.92e-284 gtf1 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
MLDBCPCB_01566 0.0 secA2 - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MLDBCPCB_01567 4.73e-210 asp3 - - S ko:K12270 - ko00000,ko02044 Accessory Sec secretory system ASP3
MLDBCPCB_01568 0.0 asp2 - - S ko:K12269 - ko00000,ko02044 Accessory Sec system GspB-transporter
MLDBCPCB_01569 0.0 - - - M - - - transferase activity, transferring glycosyl groups
MLDBCPCB_01570 6.21e-266 secY2 - - U - - - Part of the accessory SecA2 SecY2 system specifically required for export of
MLDBCPCB_01571 4.59e-248 - - - M - - - transferase activity, transferring glycosyl groups
MLDBCPCB_01573 4.41e-273 - 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 UDP binding domain
MLDBCPCB_01574 5.18e-157 - - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
MLDBCPCB_01576 1.86e-67 - - - H - - - Glycosyltransferase like family 2
MLDBCPCB_01577 3.64e-73 - - - M - - - transferase activity, transferring glycosyl groups
MLDBCPCB_01578 2.4e-40 lacA - - S - - - Maltose acetyltransferase
MLDBCPCB_01579 3.11e-34 - - GT2 S ko:K19425,ko:K19427 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
MLDBCPCB_01580 4.07e-114 tuaA - - M - - - Bacterial sugar transferase
MLDBCPCB_01581 1.18e-176 cps2D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
MLDBCPCB_01582 1.24e-159 ywqD - - D - - - Capsular exopolysaccharide family
MLDBCPCB_01583 4.1e-193 epsB - - M - - - biosynthesis protein
MLDBCPCB_01584 8.17e-221 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
MLDBCPCB_01585 7.64e-88 - - - K - - - Transcriptional regulator, HxlR family
MLDBCPCB_01586 2.67e-83 - - - - - - - -
MLDBCPCB_01588 7.54e-115 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MLDBCPCB_01589 1.81e-226 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
MLDBCPCB_01590 5.79e-117 pgpA - - I - - - Phosphatidylglycerophosphatase A
MLDBCPCB_01591 1.84e-282 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
MLDBCPCB_01592 2.52e-196 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
MLDBCPCB_01593 4.13e-192 yycI - - S - - - YycH protein
MLDBCPCB_01594 2.41e-315 yycH - - S - - - YycH protein
MLDBCPCB_01595 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MLDBCPCB_01596 3.69e-168 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
MLDBCPCB_01598 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
MLDBCPCB_01599 6.55e-97 - - - K ko:K18909 - ko00000,ko00002,ko01504,ko03000 helix_turn_helix multiple antibiotic resistance protein
MLDBCPCB_01601 1.97e-53 - - - S - - - Protein of unknown function (DUF1797)
MLDBCPCB_01602 8.93e-227 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MLDBCPCB_01603 1.09e-250 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
MLDBCPCB_01604 2.99e-289 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
MLDBCPCB_01605 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MLDBCPCB_01606 3.69e-54 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
MLDBCPCB_01607 1.38e-37 - - - - - - - -
MLDBCPCB_01608 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
MLDBCPCB_01609 7.43e-129 - - - S - - - Pfam:DUF3816
MLDBCPCB_01610 1.35e-182 - - - G - - - MucBP domain
MLDBCPCB_01611 7.87e-146 - - - - - - - -
MLDBCPCB_01612 1.11e-202 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MLDBCPCB_01613 2.41e-84 - - - K - - - Transcriptional regulator, GntR family
MLDBCPCB_01615 3.17e-219 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MLDBCPCB_01616 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
MLDBCPCB_01617 5.89e-314 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MLDBCPCB_01618 2.66e-111 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MLDBCPCB_01619 1.64e-283 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MLDBCPCB_01620 9.32e-223 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MLDBCPCB_01621 1.18e-176 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MLDBCPCB_01622 1.62e-276 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MLDBCPCB_01623 7.41e-254 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MLDBCPCB_01624 1.74e-125 - - - K - - - Acetyltransferase (GNAT) domain
MLDBCPCB_01625 5.43e-311 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
MLDBCPCB_01626 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
MLDBCPCB_01627 3.94e-144 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MLDBCPCB_01628 3.48e-192 - - - O - - - Uncharacterized protein family (UPF0051)
MLDBCPCB_01629 8.11e-139 - - - M - - - LysM domain protein
MLDBCPCB_01630 0.0 - - - EP - - - Psort location Cytoplasmic, score
MLDBCPCB_01631 4.57e-137 - - - M - - - LysM domain protein
MLDBCPCB_01632 3.81e-62 - - - - - - - -
MLDBCPCB_01634 3.44e-47 - - - S - - - PD-(D/E)XK nuclease family transposase
MLDBCPCB_01635 1.52e-205 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
MLDBCPCB_01636 2.64e-315 - 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 pyridine nucleotide-disulfide oxidoreductase
MLDBCPCB_01637 1.16e-114 XK27_07210 - - S - - - B3 4 domain
MLDBCPCB_01638 8.65e-119 - - - - - - - -
MLDBCPCB_01639 1.25e-157 pnb - - C - - - nitroreductase
MLDBCPCB_01640 3.43e-96 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Methyltransferase
MLDBCPCB_01641 1.24e-148 XK27_00915 - - C - - - Luciferase-like monooxygenase
MLDBCPCB_01642 1.46e-41 XK27_00915 - - C - - - Luciferase-like monooxygenase
MLDBCPCB_01643 1.1e-125 - - - S - - - reductase
MLDBCPCB_01644 6.23e-288 dhaT 1.1.1.202 - C ko:K00086 ko00561,ko00640,map00561,map00640 ko00000,ko00001,ko01000 Dehydrogenase
MLDBCPCB_01645 2.41e-189 - - - E - - - Glyoxalase-like domain
MLDBCPCB_01646 3.39e-186 - 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MLDBCPCB_01647 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
MLDBCPCB_01648 4.09e-200 hlyD3 - - M ko:K02005 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MLDBCPCB_01649 4.85e-167 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
MLDBCPCB_01650 4.38e-269 - - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
MLDBCPCB_01651 1.31e-103 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
MLDBCPCB_01652 2.02e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MLDBCPCB_01653 3.28e-156 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MLDBCPCB_01654 2.41e-264 coiA - - S ko:K06198 - ko00000 Competence protein
MLDBCPCB_01655 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MLDBCPCB_01656 1.4e-147 yjbH - - Q - - - Thioredoxin
MLDBCPCB_01657 7.45e-150 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
MLDBCPCB_01658 7.22e-197 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MLDBCPCB_01659 1.13e-220 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MLDBCPCB_01660 0.0 arcD - - S - - - C4-dicarboxylate anaerobic carrier
MLDBCPCB_01661 0.0 arcT - - E - - - Dipeptidase
MLDBCPCB_01662 3.66e-274 - - - EGP - - - Transporter, major facilitator family protein
MLDBCPCB_01663 0.0 gtfA 2.4.1.7 GH13 G ko:K00690 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose glucosyltransferase
MLDBCPCB_01664 3.66e-183 - - - V - - - Beta-lactamase enzyme family
MLDBCPCB_01666 5.65e-143 - - - I - - - Acid phosphatase homologues
MLDBCPCB_01667 0.0 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
MLDBCPCB_01668 1.88e-290 - - - P - - - Chloride transporter, ClC family
MLDBCPCB_01669 5.25e-149 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MLDBCPCB_01670 2.49e-189 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
MLDBCPCB_01671 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MLDBCPCB_01672 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
MLDBCPCB_01673 1.89e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
MLDBCPCB_01674 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MLDBCPCB_01675 9.52e-108 - - - - - - - -
MLDBCPCB_01676 1.83e-148 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MLDBCPCB_01677 3.95e-167 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MLDBCPCB_01678 2.77e-220 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MLDBCPCB_01679 4.45e-315 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MLDBCPCB_01680 6.04e-220 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
MLDBCPCB_01681 2.79e-179 - - - K - - - LysR substrate binding domain
MLDBCPCB_01682 1.36e-95 - - - S - - - Protein of unknown function (DUF3290)
MLDBCPCB_01683 1.2e-148 - - - S - - - Protein of unknown function (DUF421)
MLDBCPCB_01684 3.46e-208 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MLDBCPCB_01685 4.14e-28 - - - - - - - -
MLDBCPCB_01686 8e-117 ntd 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside
MLDBCPCB_01687 4.68e-197 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
MLDBCPCB_01688 2.54e-60 yrvD - - S - - - Pfam:DUF1049
MLDBCPCB_01690 6.11e-26 - - - NU - - - Mycoplasma protein of unknown function, DUF285
MLDBCPCB_01692 1.24e-201 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
MLDBCPCB_01693 2.69e-114 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MLDBCPCB_01694 8.04e-83 - - - O - - - Zinc-dependent metalloprotease
MLDBCPCB_01695 1.41e-143 - - - S - - - Membrane
MLDBCPCB_01696 1.4e-34 - - - K - - - TRANSCRIPTIONal
MLDBCPCB_01697 1.65e-83 yju3 - - I - - - Serine aminopeptidase, S33
MLDBCPCB_01698 1.56e-102 pncA - - Q - - - Isochorismatase family
MLDBCPCB_01699 1.5e-289 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MLDBCPCB_01700 1.76e-143 - - - F - - - NUDIX domain
MLDBCPCB_01701 9.73e-146 fnr - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
MLDBCPCB_01702 2.9e-120 dpsB - - P - - - Belongs to the Dps family
MLDBCPCB_01703 1.35e-46 - - - C - - - Heavy-metal-associated domain
MLDBCPCB_01704 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 E1-E2 ATPase
MLDBCPCB_01705 2e-173 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MLDBCPCB_01706 2.64e-49 - - - - - - - -
MLDBCPCB_01707 0.0 - - - S - - - SEC-C Motif Domain Protein
MLDBCPCB_01708 1.03e-37 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
MLDBCPCB_01710 0.0 - - - S - - - Putative peptidoglycan binding domain
MLDBCPCB_01711 4.03e-65 - - - - - - - -
MLDBCPCB_01712 1.15e-301 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
MLDBCPCB_01713 4.34e-121 ribB 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MLDBCPCB_01714 7.47e-148 - - - S - - - Haloacid dehalogenase-like hydrolase
MLDBCPCB_01715 8.89e-234 - - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
MLDBCPCB_01716 1.95e-127 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MLDBCPCB_01718 1.03e-72 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MLDBCPCB_01720 3.38e-102 - - - L - - - helicase activity
MLDBCPCB_01721 3.38e-294 - - - L - - - Integrase core domain
MLDBCPCB_01722 4.31e-180 - - - L - - - Bacterial dnaA protein
MLDBCPCB_01723 3.1e-127 - - - L - - - Helix-turn-helix domain
MLDBCPCB_01724 2e-205 - - - L ko:K07497 - ko00000 hmm pf00665
MLDBCPCB_01725 4.91e-80 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
MLDBCPCB_01726 8e-49 - - - - - - - -
MLDBCPCB_01727 1.94e-130 - - - K - - - DNA-templated transcription, initiation
MLDBCPCB_01728 2.94e-39 - - - - - - - -
MLDBCPCB_01729 1.41e-147 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
MLDBCPCB_01730 2.21e-91 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
MLDBCPCB_01732 3e-93 - - - - - - - -
MLDBCPCB_01752 1.31e-161 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
MLDBCPCB_01753 6.28e-63 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
MLDBCPCB_01759 3.23e-45 - - - S - - - Uncharacterised protein family (UPF0236)

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)