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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HCPBGPIE_00001	0.0	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HCPBGPIE_00002	1.4e-201	endA	-	-	V	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HCPBGPIE_00003	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HCPBGPIE_00005	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HCPBGPIE_00006	1.27e-291	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HCPBGPIE_00007	2.04e-158	-	-	-	S	-	-	-	SNARE associated Golgi protein
HCPBGPIE_00008	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
HCPBGPIE_00009	6.28e-73	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HCPBGPIE_00010	5.29e-78	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HCPBGPIE_00011	3.39e-90	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HCPBGPIE_00012	1.43e-185	-	-	-	S	-	-	-	DUF218 domain
HCPBGPIE_00013	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
HCPBGPIE_00014	9.45e-315	yhdP	-	-	S	-	-	-	Transporter associated domain
HCPBGPIE_00015	2.39e-98	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
HCPBGPIE_00016	2.9e-309	-	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HCPBGPIE_00017	9.49e-98	-	-	-	S	-	-	-	UPF0756 membrane protein
HCPBGPIE_00018	6.14e-104	-	-	-	S	-	-	-	Cupin domain
HCPBGPIE_00019	2.91e-109	-	-	-	C	-	-	-	Flavodoxin
HCPBGPIE_00020	7.79e-204	rlrB	-	-	K	-	-	-	LysR substrate binding domain protein
HCPBGPIE_00021	4.96e-217	yvgN	-	-	C	-	-	-	Aldo keto reductase
HCPBGPIE_00022	1.02e-51	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
HCPBGPIE_00023	2.12e-90	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HCPBGPIE_00024	5.51e-191	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HCPBGPIE_00025	7.5e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HCPBGPIE_00026	5.98e-206	-	-	-	S	-	-	-	Alpha beta hydrolase
HCPBGPIE_00027	2.07e-202	gspA	-	-	M	-	-	-	family 8
HCPBGPIE_00028	3.04e-154	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HCPBGPIE_00029	7.49e-124	-	-	-	-	-	-	-	-
HCPBGPIE_00030	1.2e-206	-	-	-	S	-	-	-	EDD domain protein, DegV family
HCPBGPIE_00031	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
HCPBGPIE_00032	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HCPBGPIE_00033	1.58e-264	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
HCPBGPIE_00034	5.61e-222	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HCPBGPIE_00035	1.92e-91	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HCPBGPIE_00036	2.58e-85	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
HCPBGPIE_00037	4.44e-91	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
HCPBGPIE_00038	8.39e-238	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
HCPBGPIE_00039	5.33e-77	-	-	-	S	-	-	-	COG5546 Small integral membrane protein
HCPBGPIE_00040	4.55e-58	-	-	-	-	-	-	-	-
HCPBGPIE_00044	1.61e-236	-	-	-	-	-	-	-	-
HCPBGPIE_00048	1.18e-18	-	-	-	LM	-	-	-	gp58-like protein
HCPBGPIE_00049	8.44e-274	-	-	-	M	-	-	-	Prophage endopeptidase tail
HCPBGPIE_00050	3.42e-145	-	-	-	S	-	-	-	Phage tail protein
HCPBGPIE_00051	4.39e-241	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
HCPBGPIE_00053	1.1e-11	-	-	-	S	-	-	-	Phage tail assembly chaperone proteins, TAC
HCPBGPIE_00054	2.42e-84	-	-	-	S	-	-	-	Phage tail tube protein
HCPBGPIE_00055	5.48e-15	-	-	-	S	-	-	-	Phage tail tube protein
HCPBGPIE_00056	5.42e-47	-	-	-	S	-	-	-	Protein of unknown function (DUF806)
HCPBGPIE_00057	7.22e-50	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
HCPBGPIE_00058	3.64e-52	-	-	-	S	-	-	-	Phage head-tail joining protein
HCPBGPIE_00059	4.7e-48	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HCPBGPIE_00060	9e-201	-	-	-	S	-	-	-	Phage capsid family
HCPBGPIE_00061	9.39e-150	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
HCPBGPIE_00062	3.9e-254	-	-	-	S	-	-	-	Phage portal protein
HCPBGPIE_00064	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
HCPBGPIE_00065	9.66e-82	-	-	-	L	-	-	-	Phage terminase, small subunit
HCPBGPIE_00066	1.8e-75	-	-	-	L	-	-	-	HNH nucleases
HCPBGPIE_00067	2.15e-190	bcgIA	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	site-specific DNA-methyltransferase (adenine-specific) activity
HCPBGPIE_00068	5.46e-109	-	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	site-specific DNA-methyltransferase (adenine-specific) activity
HCPBGPIE_00076	1.02e-72	-	-	-	-	-	-	-	-
HCPBGPIE_00077	9.11e-167	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HCPBGPIE_00078	5.3e-201	pi112	-	-	L	-	-	-	PDDEXK-like domain of unknown function (DUF3799)
HCPBGPIE_00079	4.57e-197	-	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
HCPBGPIE_00082	5.18e-37	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
HCPBGPIE_00083	1.13e-20	-	-	-	-	-	-	-	-
HCPBGPIE_00088	1.01e-176	-	-	-	K	ko:K07741	-	ko00000	BRO family, N-terminal domain
HCPBGPIE_00089	6.21e-43	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HCPBGPIE_00090	3.02e-62	-	-	-	K	-	-	-	Helix-turn-helix domain
HCPBGPIE_00091	1.66e-92	-	-	-	S	-	-	-	IrrE N-terminal-like domain
HCPBGPIE_00092	2.12e-07	-	-	-	-	-	-	-	-
HCPBGPIE_00093	3.66e-42	-	-	-	-	-	-	-	-
HCPBGPIE_00094	3.03e-13	-	-	-	M	-	-	-	LysM domain
HCPBGPIE_00097	3.09e-63	-	-	-	-	-	-	-	-
HCPBGPIE_00098	1.54e-89	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HCPBGPIE_00099	1.97e-26	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HCPBGPIE_00100	8.08e-281	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HCPBGPIE_00101	1.01e-109	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
HCPBGPIE_00102	6.82e-74	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HCPBGPIE_00103	1.17e-135	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HCPBGPIE_00104	7.01e-153	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HCPBGPIE_00105	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
HCPBGPIE_00106	5.69e-207	-	-	-	EG	-	-	-	EamA-like transporter family
HCPBGPIE_00107	1.75e-161	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
HCPBGPIE_00108	9.09e-113	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
HCPBGPIE_00109	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HCPBGPIE_00110	5.16e-220	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
HCPBGPIE_00111	1.71e-217	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
HCPBGPIE_00112	4.11e-274	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
HCPBGPIE_00113	8.91e-248	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HCPBGPIE_00114	5.52e-119	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
HCPBGPIE_00115	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HCPBGPIE_00116	2.43e-241	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein-like domain
HCPBGPIE_00117	5.79e-214	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HCPBGPIE_00118	8.01e-228	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HCPBGPIE_00119	4.38e-161	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
HCPBGPIE_00120	3.69e-87	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
HCPBGPIE_00121	8.31e-169	lytT	-	-	K	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator receiver
HCPBGPIE_00122	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	LytS YhcK-type transmembrane receptor domain protein
HCPBGPIE_00123	1.54e-191	-	-	-	O	-	-	-	Band 7 protein
HCPBGPIE_00124	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
HCPBGPIE_00125	1.4e-199	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HCPBGPIE_00126	1.43e-51	-	-	-	S	-	-	-	Cytochrome B5
HCPBGPIE_00127	5.87e-147	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
HCPBGPIE_00128	3.86e-205	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HCPBGPIE_00129	1.18e-76	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HCPBGPIE_00130	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
HCPBGPIE_00131	9.11e-106	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
HCPBGPIE_00132	2.23e-299	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HCPBGPIE_00133	1.07e-301	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
HCPBGPIE_00134	5.43e-185	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
HCPBGPIE_00135	2.32e-43	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
HCPBGPIE_00136	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HCPBGPIE_00137	5.19e-27	-	-	-	-	-	-	-	-
HCPBGPIE_00138	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HCPBGPIE_00139	6.96e-201	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HCPBGPIE_00140	9.54e-85	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
HCPBGPIE_00141	1.43e-141	yvrI	-	-	K	ko:K03091,ko:K03093	-	ko00000,ko03021	sigma factor activity
HCPBGPIE_00142	3.07e-265	-	-	-	G	-	-	-	Transporter, major facilitator family protein
HCPBGPIE_00143	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HCPBGPIE_00144	2.87e-143	-	-	-	T	ko:K10716	-	ko00000,ko02000	Ion transport 2 domain protein
HCPBGPIE_00145	1.11e-101	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HCPBGPIE_00146	1.59e-287	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HCPBGPIE_00147	1.68e-124	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
HCPBGPIE_00148	5.59e-249	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HCPBGPIE_00149	9.03e-229	rihA	-	-	F	ko:K01250	-	ko00000,ko01000	Inosine-uridine preferring nucleoside hydrolase
HCPBGPIE_00151	0.0	-	-	-	L	-	-	-	PLD-like domain
HCPBGPIE_00152	7.16e-47	higA	-	-	K	ko:K21498	-	ko00000,ko02048	addiction module antidote protein HigA
HCPBGPIE_00153	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HCPBGPIE_00154	1.32e-59	hsdS	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain
HCPBGPIE_00155	0.0	cadA	-	-	P	-	-	-	P-type ATPase
HCPBGPIE_00156	5.23e-276	-	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Metalloenzyme superfamily
HCPBGPIE_00157	4.44e-11	-	-	-	-	-	-	-	-
HCPBGPIE_00158	1.83e-197	-	-	-	GM	-	-	-	NAD(P)H-binding
HCPBGPIE_00159	5.49e-97	ywnA	-	-	K	-	-	-	Transcriptional regulator
HCPBGPIE_00160	1.77e-207	proWY	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, QAT family
HCPBGPIE_00161	2.35e-139	proWZ	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HCPBGPIE_00162	1.01e-180	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HCPBGPIE_00163	1.96e-138	-	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
HCPBGPIE_00164	3.53e-100	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HCPBGPIE_00165	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HCPBGPIE_00166	8e-275	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HCPBGPIE_00167	5.25e-140	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HCPBGPIE_00168	4.92e-244	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HCPBGPIE_00169	4.16e-198	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HCPBGPIE_00170	5.14e-217	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HCPBGPIE_00171	2.41e-280	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
HCPBGPIE_00172	1.41e-53	-	1.3.5.4	-	S	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FMN binding
HCPBGPIE_00173	5.71e-152	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HCPBGPIE_00174	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
HCPBGPIE_00175	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HCPBGPIE_00177	3.16e-260	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HCPBGPIE_00178	0.0	-	-	-	L	-	-	-	DNA helicase
HCPBGPIE_00179	7.04e-107	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
HCPBGPIE_00180	5.96e-241	-	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
HCPBGPIE_00181	5.54e-243	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HCPBGPIE_00182	4.38e-215	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HCPBGPIE_00183	2.08e-283	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
HCPBGPIE_00184	1.09e-227	-	-	-	-	-	-	-	-
HCPBGPIE_00185	5.9e-168	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
HCPBGPIE_00187	4.74e-208	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
HCPBGPIE_00188	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HCPBGPIE_00189	5.3e-200	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
HCPBGPIE_00190	6.03e-128	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HCPBGPIE_00191	9.83e-204	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HCPBGPIE_00192	2.74e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
HCPBGPIE_00193	5.5e-203	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HCPBGPIE_00194	1.66e-214	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HCPBGPIE_00195	2.31e-156	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HCPBGPIE_00196	4.12e-164	-	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
HCPBGPIE_00197	5.24e-191	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HCPBGPIE_00198	3.17e-314	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HCPBGPIE_00199	3.53e-229	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HCPBGPIE_00200	1.6e-100	-	-	-	-	-	-	-	-
HCPBGPIE_00201	1.89e-189	yidA	-	-	S	-	-	-	hydrolase
HCPBGPIE_00202	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
HCPBGPIE_00203	4.82e-188	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
HCPBGPIE_00204	9.28e-89	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
HCPBGPIE_00205	1.04e-85	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HCPBGPIE_00206	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HCPBGPIE_00207	5.29e-300	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HCPBGPIE_00208	9.43e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HCPBGPIE_00209	3.07e-301	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCPBGPIE_00210	1.86e-212	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HCPBGPIE_00211	4.29e-162	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
HCPBGPIE_00212	0.0	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HCPBGPIE_00213	6.85e-190	-	-	-	G	-	-	-	Right handed beta helix region
HCPBGPIE_00214	8.64e-179	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HCPBGPIE_00215	6.21e-207	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
HCPBGPIE_00216	1.51e-154	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
HCPBGPIE_00217	1.11e-111	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HCPBGPIE_00218	4.93e-123	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HCPBGPIE_00219	2.14e-203	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HCPBGPIE_00220	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HCPBGPIE_00221	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HCPBGPIE_00222	9.84e-160	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
HCPBGPIE_00223	1.68e-240	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
HCPBGPIE_00224	4.83e-212	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HCPBGPIE_00225	0.0	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HCPBGPIE_00226	1e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HCPBGPIE_00227	1.23e-297	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
HCPBGPIE_00228	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HCPBGPIE_00229	2.63e-08	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
HCPBGPIE_00230	2.2e-79	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HCPBGPIE_00231	1.54e-269	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HCPBGPIE_00232	1.3e-82	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HCPBGPIE_00233	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
HCPBGPIE_00234	2.75e-309	codA	3.5.4.1	-	F	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	cytosine deaminase
HCPBGPIE_00235	2.06e-188	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
HCPBGPIE_00236	2.7e-145	-	-	-	S	-	-	-	(CBS) domain
HCPBGPIE_00237	7.98e-132	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HCPBGPIE_00238	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HCPBGPIE_00239	1.18e-51	yabO	-	-	J	-	-	-	S4 domain protein
HCPBGPIE_00240	7.15e-75	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HCPBGPIE_00241	5.75e-103	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
HCPBGPIE_00242	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HCPBGPIE_00243	3.68e-125	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HCPBGPIE_00244	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HCPBGPIE_00245	7.93e-219	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HCPBGPIE_00246	1.53e-241	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HCPBGPIE_00247	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HCPBGPIE_00248	0.0	-	-	-	O	-	-	-	Arylsulfotransferase (ASST)
HCPBGPIE_00249	1.34e-146	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HCPBGPIE_00251	1.83e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HCPBGPIE_00252	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HCPBGPIE_00253	4.41e-106	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	YbaK proline--tRNA ligase associated domain protein
HCPBGPIE_00254	0.0	-	-	-	E	-	-	-	amino acid
HCPBGPIE_00255	0.0	ydaO	-	-	E	-	-	-	amino acid
HCPBGPIE_00256	1.07e-52	-	-	-	-	-	-	-	-
HCPBGPIE_00257	8.81e-89	-	-	-	K	-	-	-	Transcriptional regulator
HCPBGPIE_00258	7.49e-300	-	-	-	EGP	-	-	-	Major Facilitator
HCPBGPIE_00259	6.65e-145	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
HCPBGPIE_00260	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
HCPBGPIE_00261	1.73e-148	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
HCPBGPIE_00262	5e-124	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HCPBGPIE_00263	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HCPBGPIE_00264	1.58e-238	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HCPBGPIE_00265	2.11e-66	-	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
HCPBGPIE_00266	1.88e-68	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
HCPBGPIE_00267	1.38e-226	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HCPBGPIE_00268	3.31e-200	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HCPBGPIE_00269	5.93e-237	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HCPBGPIE_00270	1.79e-214	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HCPBGPIE_00271	5.04e-175	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
HCPBGPIE_00272	0.0	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
HCPBGPIE_00273	1.43e-208	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
HCPBGPIE_00274	2.77e-221	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HCPBGPIE_00275	5.44e-277	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HCPBGPIE_00276	5.89e-201	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	PFAM extracellular solute-binding protein, family 3
HCPBGPIE_00277	2.85e-114	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
HCPBGPIE_00278	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HCPBGPIE_00279	3.57e-150	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
HCPBGPIE_00280	4.16e-19	-	-	-	-	-	-	-	-
HCPBGPIE_00281	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HCPBGPIE_00282	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HCPBGPIE_00283	5.51e-316	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HCPBGPIE_00284	8.05e-208	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HCPBGPIE_00285	5.73e-239	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HCPBGPIE_00286	1.94e-218	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HCPBGPIE_00288	1.83e-21	-	-	-	-	-	-	-	-
HCPBGPIE_00289	4.72e-134	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HCPBGPIE_00291	1.31e-243	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HCPBGPIE_00292	7.62e-290	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HCPBGPIE_00293	2.51e-182	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HCPBGPIE_00294	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HCPBGPIE_00295	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HCPBGPIE_00296	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HCPBGPIE_00297	1.43e-47	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HCPBGPIE_00298	3.43e-189	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
HCPBGPIE_00299	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HCPBGPIE_00300	7.73e-109	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HCPBGPIE_00301	9.61e-137	-	-	-	-	-	-	-	-
HCPBGPIE_00302	1.84e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HCPBGPIE_00303	1.38e-228	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
HCPBGPIE_00304	6.95e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
HCPBGPIE_00305	1.46e-112	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HCPBGPIE_00306	3.55e-99	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
HCPBGPIE_00307	3.7e-133	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HCPBGPIE_00308	2.76e-215	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HCPBGPIE_00309	1.31e-213	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HCPBGPIE_00310	1.43e-87	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HCPBGPIE_00311	0.0	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
HCPBGPIE_00312	6.61e-195	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HCPBGPIE_00313	7.48e-165	ybbR	-	-	S	-	-	-	YbbR-like protein
HCPBGPIE_00314	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HCPBGPIE_00315	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HCPBGPIE_00316	5.17e-70	-	-	-	-	-	-	-	-
HCPBGPIE_00317	0.0	oatA	-	-	I	-	-	-	Acyltransferase
HCPBGPIE_00318	4.32e-105	-	-	-	K	-	-	-	Transcriptional regulator
HCPBGPIE_00319	9.84e-194	-	-	-	S	-	-	-	Cof-like hydrolase
HCPBGPIE_00320	2.2e-110	lytE	-	-	M	-	-	-	Lysin motif
HCPBGPIE_00322	2.7e-172	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
HCPBGPIE_00323	0.0	yclK	-	-	T	-	-	-	Histidine kinase
HCPBGPIE_00324	2.71e-200	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HCPBGPIE_00325	6.42e-140	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
HCPBGPIE_00326	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HCPBGPIE_00327	2.08e-208	xylR	-	-	GK	-	-	-	ROK family
HCPBGPIE_00328	0.0	xylB	2.7.1.17, 2.7.1.53	-	G	ko:K00854,ko:K00880	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the FGGY kinase family
HCPBGPIE_00329	3.05e-198	-	-	-	KT	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	YcbB domain
HCPBGPIE_00330	1.31e-243	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HCPBGPIE_00331	3.94e-221	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
HCPBGPIE_00332	3.18e-206	-	-	-	EG	-	-	-	EamA-like transporter family
HCPBGPIE_00333	7.03e-134	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
HCPBGPIE_00334	1.31e-81	-	-	-	S	-	-	-	Cupredoxin-like domain
HCPBGPIE_00335	2.2e-65	-	-	-	S	-	-	-	Cupredoxin-like domain
HCPBGPIE_00336	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HCPBGPIE_00337	1.23e-110	-	-	-	-	-	-	-	-
HCPBGPIE_00339	2.13e-74	-	-	-	-	-	-	-	-
HCPBGPIE_00341	4.95e-92	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HCPBGPIE_00342	2.54e-199	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HCPBGPIE_00344	2.6e-135	-	-	-	-	-	-	-	-
HCPBGPIE_00345	9.61e-213	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HCPBGPIE_00346	3.65e-291	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HCPBGPIE_00347	2.6e-167	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HCPBGPIE_00348	9.02e-201	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HCPBGPIE_00349	1.81e-225	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HCPBGPIE_00350	0.0	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
HCPBGPIE_00351	2.13e-280	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HCPBGPIE_00352	2.82e-133	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HCPBGPIE_00353	1.35e-238	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HCPBGPIE_00354	9.85e-59	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
HCPBGPIE_00355	3.03e-50	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HCPBGPIE_00356	5.66e-143	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HCPBGPIE_00357	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HCPBGPIE_00358	1.55e-109	-	-	-	-	-	-	-	-
HCPBGPIE_00359	8.48e-203	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HCPBGPIE_00360	9e-72	-	-	-	S	-	-	-	Mazg nucleotide pyrophosphohydrolase
HCPBGPIE_00361	3.67e-46	-	-	-	-	-	-	-	-
HCPBGPIE_00362	3.03e-83	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HCPBGPIE_00363	0.0	-	-	-	E	ko:K03294	-	ko00000	amino acid
HCPBGPIE_00364	5.46e-183	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HCPBGPIE_00365	7.57e-119	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HCPBGPIE_00366	2.17e-52	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HCPBGPIE_00367	1.21e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HCPBGPIE_00368	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HCPBGPIE_00369	4.23e-76	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HCPBGPIE_00370	4.94e-285	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HCPBGPIE_00371	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HCPBGPIE_00372	1.57e-168	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HCPBGPIE_00373	1.81e-50	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HCPBGPIE_00374	7.82e-240	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HCPBGPIE_00375	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HCPBGPIE_00376	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
HCPBGPIE_00377	1.05e-77	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HCPBGPIE_00378	1.1e-34	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HCPBGPIE_00379	6.95e-159	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HCPBGPIE_00380	5.46e-152	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HCPBGPIE_00381	3.75e-212	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HCPBGPIE_00382	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HCPBGPIE_00383	4.26e-168	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HCPBGPIE_00384	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HCPBGPIE_00385	8.26e-222	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HCPBGPIE_00386	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HCPBGPIE_00387	4.44e-273	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HCPBGPIE_00388	6.66e-43	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HCPBGPIE_00389	4.37e-148	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HCPBGPIE_00390	9e-72	-	-	-	-	-	-	-	-
HCPBGPIE_00391	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HCPBGPIE_00392	3.2e-100	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HCPBGPIE_00393	1.69e-192	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HCPBGPIE_00394	6.95e-205	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HCPBGPIE_00395	4.02e-58	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HCPBGPIE_00396	3.13e-309	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HCPBGPIE_00397	1.61e-192	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HCPBGPIE_00398	2.24e-92	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HCPBGPIE_00399	2.27e-93	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
HCPBGPIE_00400	1.22e-147	-	-	-	J	-	-	-	2'-5' RNA ligase superfamily
HCPBGPIE_00401	2.13e-256	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HCPBGPIE_00402	3.84e-170	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HCPBGPIE_00403	5.07e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HCPBGPIE_00404	1.77e-72	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
HCPBGPIE_00405	2.68e-67	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HCPBGPIE_00406	1.34e-144	-	-	-	K	-	-	-	Transcriptional regulator
HCPBGPIE_00410	4.21e-116	-	-	-	S	-	-	-	Protein conserved in bacteria
HCPBGPIE_00411	2.09e-223	-	-	-	-	-	-	-	-
HCPBGPIE_00412	4.87e-203	-	-	-	-	-	-	-	-
HCPBGPIE_00413	1.54e-67	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HCPBGPIE_00414	1.99e-131	msrA	1.8.4.11	-	C	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HCPBGPIE_00415	3.42e-197	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HCPBGPIE_00416	1.28e-18	-	-	-	-	-	-	-	-
HCPBGPIE_00417	8.1e-281	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HCPBGPIE_00418	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HCPBGPIE_00419	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HCPBGPIE_00420	7.13e-227	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HCPBGPIE_00421	1.18e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF3042)
HCPBGPIE_00422	7.66e-88	yqhL	-	-	P	-	-	-	Rhodanese-like protein
HCPBGPIE_00423	1.02e-234	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
HCPBGPIE_00424	7.07e-48	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
HCPBGPIE_00425	1.38e-59	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
HCPBGPIE_00426	1.43e-16	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
HCPBGPIE_00427	9.34e-130	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HCPBGPIE_00428	1.53e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HCPBGPIE_00429	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HCPBGPIE_00430	0.0	-	-	-	S	-	-	-	membrane
HCPBGPIE_00431	1.56e-90	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
HCPBGPIE_00438	1.74e-125	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HCPBGPIE_00439	1.34e-311	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
HCPBGPIE_00440	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
HCPBGPIE_00441	3.94e-144	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HCPBGPIE_00442	3.48e-192	-	-	-	O	-	-	-	Uncharacterized protein family (UPF0051)
HCPBGPIE_00443	2.73e-148	-	-	-	M	-	-	-	LysM domain protein
HCPBGPIE_00444	0.0	-	-	-	EP	-	-	-	Psort location Cytoplasmic, score
HCPBGPIE_00445	4.57e-137	-	-	-	M	-	-	-	LysM domain protein
HCPBGPIE_00446	5.5e-197	yeaE	-	-	S	-	-	-	Aldo keto
HCPBGPIE_00447	4.63e-101	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HCPBGPIE_00448	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
HCPBGPIE_00449	3.77e-102	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HCPBGPIE_00450	5.03e-111	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HCPBGPIE_00451	7.03e-33	-	-	-	-	-	-	-	-
HCPBGPIE_00452	8.28e-135	-	-	-	V	-	-	-	VanZ like family
HCPBGPIE_00453	1.72e-303	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HCPBGPIE_00454	1.25e-111	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HCPBGPIE_00455	0.0	-	-	-	EGP	-	-	-	Major Facilitator
HCPBGPIE_00456	4.29e-119	tag1	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HCPBGPIE_00457	2.71e-280	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HCPBGPIE_00458	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HCPBGPIE_00459	1.45e-55	-	-	-	-	-	-	-	-
HCPBGPIE_00460	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HCPBGPIE_00461	3.85e-45	-	-	-	-	-	-	-	-
HCPBGPIE_00464	1.34e-24	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HCPBGPIE_00466	5.52e-156	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HCPBGPIE_00467	8.39e-80	-	-	-	L	-	-	-	Helix-turn-helix domain
HCPBGPIE_00470	1.01e-195	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HCPBGPIE_00471	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
HCPBGPIE_00472	4.4e-112	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HCPBGPIE_00473	1.11e-224	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HCPBGPIE_00474	3.06e-150	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HCPBGPIE_00475	3.08e-146	-	-	-	-	-	-	-	-
HCPBGPIE_00476	8.42e-237	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
HCPBGPIE_00477	1.63e-207	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HCPBGPIE_00478	1.52e-43	-	-	-	-	-	-	-	-
HCPBGPIE_00479	4.68e-145	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HCPBGPIE_00480	9.17e-59	-	-	-	-	-	-	-	-
HCPBGPIE_00482	6.82e-72	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HCPBGPIE_00483	4.71e-114	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HCPBGPIE_00484	3.36e-136	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
HCPBGPIE_00485	8.17e-285	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HCPBGPIE_00486	2.97e-136	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
HCPBGPIE_00487	5.43e-276	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
HCPBGPIE_00488	9.3e-61	-	-	-	-	-	-	-	-
HCPBGPIE_00489	1.49e-54	-	-	-	-	-	-	-	-
HCPBGPIE_00491	3.88e-213	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HCPBGPIE_00492	2.15e-194	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HCPBGPIE_00493	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HCPBGPIE_00494	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HCPBGPIE_00495	1.08e-76	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HCPBGPIE_00496	2.62e-282	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
HCPBGPIE_00497	0.0	yhaN	-	-	L	-	-	-	AAA domain
HCPBGPIE_00498	3.96e-178	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HCPBGPIE_00500	4.99e-101	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
HCPBGPIE_00501	2.7e-175	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HCPBGPIE_00502	6.64e-279	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HCPBGPIE_00503	3.73e-157	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HCPBGPIE_00504	3.31e-37	-	-	-	S	-	-	-	YSIRK type signal peptide
HCPBGPIE_00505	7.51e-77	-	2.1.1.72, 3.1.21.3	AA10,CBM73	M	ko:K01154,ko:K02014,ko:K03933,ko:K07316	-	ko00000,ko01000,ko02000,ko02048	domain protein
HCPBGPIE_00506	8.18e-102	-	-	-	V	-	-	-	Pfam:Methyltransf_26
HCPBGPIE_00507	3.22e-68	-	-	-	-	-	-	-	-
HCPBGPIE_00508	2.02e-88	-	-	-	-	-	-	-	-
HCPBGPIE_00516	2.25e-25	-	-	-	S	-	-	-	Helix-turn-helix domain
HCPBGPIE_00517	3.4e-13	-	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
HCPBGPIE_00519	4.56e-172	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HCPBGPIE_00520	1.79e-121	-	-	-	-	-	-	-	-
HCPBGPIE_00521	1.46e-118	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HCPBGPIE_00522	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HCPBGPIE_00523	3.87e-200	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
HCPBGPIE_00524	3.39e-226	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HCPBGPIE_00525	3.8e-316	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HCPBGPIE_00526	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HCPBGPIE_00527	2.44e-20	-	-	-	-	-	-	-	-
HCPBGPIE_00528	1.11e-78	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
HCPBGPIE_00529	2.01e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HCPBGPIE_00530	2.06e-297	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HCPBGPIE_00531	5.54e-303	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HCPBGPIE_00532	4.94e-288	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HCPBGPIE_00533	3.58e-208	-	-	-	S	-	-	-	Tetratricopeptide repeat
HCPBGPIE_00534	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HCPBGPIE_00535	1.74e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HCPBGPIE_00536	1.44e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HCPBGPIE_00537	9.21e-200	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HCPBGPIE_00538	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HCPBGPIE_00539	1.98e-82	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HCPBGPIE_00540	7.1e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
HCPBGPIE_00541	3.4e-138	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
HCPBGPIE_00542	3.51e-251	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HCPBGPIE_00543	3.05e-116	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HCPBGPIE_00544	6.8e-129	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
HCPBGPIE_00545	6.37e-60	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
HCPBGPIE_00546	7.54e-284	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HCPBGPIE_00547	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HCPBGPIE_00548	3.52e-177	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
HCPBGPIE_00549	7.04e-63	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
HCPBGPIE_00550	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
HCPBGPIE_00551	2.13e-311	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HCPBGPIE_00552	9.42e-232	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
HCPBGPIE_00553	2.44e-267	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
HCPBGPIE_00554	1.38e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HCPBGPIE_00555	6.08e-102	-	-	-	-	-	-	-	-
HCPBGPIE_00556	9.99e-44	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HCPBGPIE_00557	1.69e-229	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic
HCPBGPIE_00558	4.37e-39	-	-	-	-	-	-	-	-
HCPBGPIE_00559	3.3e-265	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
HCPBGPIE_00561	5.28e-76	-	-	-	-	-	-	-	-
HCPBGPIE_00562	3.07e-264	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HCPBGPIE_00563	6.63e-281	yojA	-	-	EG	ko:K03299	-	ko00000,ko02000	GntP family permease
HCPBGPIE_00564	5.77e-104	-	-	-	KT	ko:K02647	-	ko00000,ko03000	Putative sugar diacid recognition
HCPBGPIE_00565	2.58e-254	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HCPBGPIE_00566	1.62e-276	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HCPBGPIE_00567	1.43e-177	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HCPBGPIE_00568	9.32e-223	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HCPBGPIE_00569	1.64e-283	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HCPBGPIE_00570	2.66e-111	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HCPBGPIE_00571	1.45e-314	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HCPBGPIE_00572	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HCPBGPIE_00573	1.11e-219	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HCPBGPIE_00574	5.02e-105	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HCPBGPIE_00575	2.09e-166	-	-	-	S	-	-	-	Putative threonine/serine exporter
HCPBGPIE_00576	2.17e-43	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HCPBGPIE_00577	2.32e-161	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
HCPBGPIE_00578	4.04e-212	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
HCPBGPIE_00579	3.11e-153	-	-	-	S	-	-	-	membrane
HCPBGPIE_00580	4.71e-142	-	-	-	S	-	-	-	VIT family
HCPBGPIE_00581	4.83e-108	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HCPBGPIE_00582	1.39e-173	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HCPBGPIE_00583	1.29e-193	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HCPBGPIE_00584	1.06e-142	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HCPBGPIE_00585	2.11e-140	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HCPBGPIE_00586	7.14e-276	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HCPBGPIE_00587	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HCPBGPIE_00588	8.46e-77	-	-	-	-	-	-	-	-
HCPBGPIE_00589	5.33e-98	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HCPBGPIE_00590	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HCPBGPIE_00591	6.51e-161	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HCPBGPIE_00592	1.94e-211	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HCPBGPIE_00594	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HCPBGPIE_00595	5.59e-134	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
HCPBGPIE_00596	1.93e-241	-	-	-	I	-	-	-	Alpha beta
HCPBGPIE_00597	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
HCPBGPIE_00598	2.22e-151	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
HCPBGPIE_00599	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
HCPBGPIE_00600	7.21e-205	-	-	-	K	-	-	-	LysR family
HCPBGPIE_00601	1.03e-142	-	-	-	I	-	-	-	Alpha/beta hydrolase family
HCPBGPIE_00602	1.56e-193	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HCPBGPIE_00603	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
HCPBGPIE_00604	3.29e-204	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
HCPBGPIE_00605	4.25e-55	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
HCPBGPIE_00606	9.38e-188	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HCPBGPIE_00607	2.83e-224	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
HCPBGPIE_00608	1.24e-157	citR	-	-	K	-	-	-	sugar-binding domain protein
HCPBGPIE_00609	6.12e-216	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HCPBGPIE_00610	3.13e-168	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HCPBGPIE_00611	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HCPBGPIE_00612	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HCPBGPIE_00613	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
HCPBGPIE_00614	5.46e-207	mleR	-	-	K	-	-	-	LysR family
HCPBGPIE_00615	2.87e-144	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HCPBGPIE_00616	1.35e-263	adh	1.1.1.1	-	C	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding alcohol dehydrogenase family protein
HCPBGPIE_00617	0.0	-	-	-	L	-	-	-	PFAM plasmid pRiA4b ORF-3 family protein
HCPBGPIE_00618	8.63e-213	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HCPBGPIE_00619	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
HCPBGPIE_00620	1.36e-35	-	-	-	-	-	-	-	-
HCPBGPIE_00621	3.67e-255	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HCPBGPIE_00622	1.08e-96	-	-	-	-	-	-	-	-
HCPBGPIE_00623	9.29e-290	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HCPBGPIE_00624	3.05e-69	-	-	-	-	-	-	-	-
HCPBGPIE_00625	3.55e-147	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
HCPBGPIE_00626	7.05e-101	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HCPBGPIE_00627	2.6e-27	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HCPBGPIE_00628	1.47e-41	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
HCPBGPIE_00629	7.59e-162	-	-	-	M	-	-	-	hydrolase, family 25
HCPBGPIE_00630	1.24e-71	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
HCPBGPIE_00631	1.41e-27	-	-	-	-	-	-	-	-
HCPBGPIE_00635	2.02e-170	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
HCPBGPIE_00637	0.0	spoIIQ	-	-	M	ko:K06386	-	ko00000	Peptidase family M23
HCPBGPIE_00638	3.07e-203	-	-	-	S	-	-	-	Phage tail protein
HCPBGPIE_00639	0.0	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
HCPBGPIE_00640	8.23e-28	-	-	-	-	-	-	-	-
HCPBGPIE_00642	1.98e-141	-	-	-	-	-	-	-	-
HCPBGPIE_00643	6.14e-97	-	-	-	-	-	-	-	-
HCPBGPIE_00644	4.37e-81	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
HCPBGPIE_00645	4.51e-54	-	-	-	S	-	-	-	Phage head-tail joining protein
HCPBGPIE_00646	9.88e-91	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HCPBGPIE_00647	1.71e-264	-	-	-	S	-	-	-	Phage capsid family
HCPBGPIE_00648	1.18e-146	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
HCPBGPIE_00649	3.76e-306	-	-	-	S	-	-	-	Phage portal protein
HCPBGPIE_00653	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
HCPBGPIE_00654	1.62e-100	-	-	-	L	-	-	-	Phage terminase, small subunit
HCPBGPIE_00655	1.1e-198	-	-	-	L	-	-	-	HNH nucleases
HCPBGPIE_00657	8.92e-06	-	-	-	-	-	-	-	-
HCPBGPIE_00658	7.73e-109	-	-	-	S	-	-	-	Phage transcriptional regulator, ArpU family
HCPBGPIE_00665	2.68e-172	-	-	-	-	-	-	-	-
HCPBGPIE_00666	9e-91	-	-	-	-	-	-	-	-
HCPBGPIE_00668	7.26e-53	-	-	-	S	-	-	-	HNH endonuclease
HCPBGPIE_00671	1.43e-174	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HCPBGPIE_00672	1.34e-111	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
HCPBGPIE_00673	6.58e-172	-	-	-	L	-	-	-	DnaD domain protein
HCPBGPIE_00675	8.04e-27	-	-	-	-	-	-	-	-
HCPBGPIE_00679	1.1e-157	-	-	-	K	-	-	-	Peptidase S24-like
HCPBGPIE_00680	3.73e-39	-	-	-	S	-	-	-	Short C-terminal domain
HCPBGPIE_00681	4.12e-79	-	-	-	-	-	-	-	-
HCPBGPIE_00682	4.4e-34	-	-	-	-	-	-	-	-
HCPBGPIE_00684	2.06e-40	-	-	-	-	-	-	-	-
HCPBGPIE_00687	1.41e-179	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HCPBGPIE_00689	1.03e-59	yrvD	-	-	S	-	-	-	Pfam:DUF1049
HCPBGPIE_00690	4.68e-197	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HCPBGPIE_00691	8e-117	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
HCPBGPIE_00692	1.01e-28	-	-	-	-	-	-	-	-
HCPBGPIE_00693	3.46e-208	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HCPBGPIE_00694	1.2e-148	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
HCPBGPIE_00695	9.59e-96	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
HCPBGPIE_00696	3.98e-229	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HCPBGPIE_00697	7.37e-275	-	1.5.1.36	-	S	ko:K19784,ko:K22393,ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
HCPBGPIE_00698	8.9e-131	-	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
HCPBGPIE_00700	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HCPBGPIE_00701	1.34e-232	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
HCPBGPIE_00702	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HCPBGPIE_00703	9.49e-262	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HCPBGPIE_00704	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HCPBGPIE_00705	7.01e-60	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HCPBGPIE_00706	2.47e-225	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HCPBGPIE_00707	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HCPBGPIE_00708	0.0	-	-	-	M	-	-	-	domain protein
HCPBGPIE_00709	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
HCPBGPIE_00710	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HCPBGPIE_00711	8.53e-95	-	-	-	-	-	-	-	-
HCPBGPIE_00712	7.96e-97	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
HCPBGPIE_00713	5e-17	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
HCPBGPIE_00715	1.82e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HCPBGPIE_00716	1.98e-118	-	-	-	-	-	-	-	-
HCPBGPIE_00717	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HCPBGPIE_00718	6.39e-234	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HCPBGPIE_00719	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
HCPBGPIE_00720	7.6e-113	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
HCPBGPIE_00721	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
HCPBGPIE_00722	1.86e-63	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
HCPBGPIE_00723	2.1e-214	-	-	-	C	-	-	-	Aldo keto reductase
HCPBGPIE_00724	6.13e-175	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
HCPBGPIE_00725	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HCPBGPIE_00726	1.41e-265	-	-	-	P	-	-	-	Voltage gated chloride channel
HCPBGPIE_00727	1.13e-289	sptS	-	-	T	-	-	-	Histidine kinase
HCPBGPIE_00728	3.15e-153	dltr	-	-	K	-	-	-	response regulator
HCPBGPIE_00729	1.76e-112	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
HCPBGPIE_00730	1.76e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HCPBGPIE_00731	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HCPBGPIE_00732	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HCPBGPIE_00733	1.26e-243	flp	-	-	V	-	-	-	Beta-lactamase
HCPBGPIE_00734	7.15e-122	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HCPBGPIE_00735	5.66e-158	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
HCPBGPIE_00736	1.3e-50	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
HCPBGPIE_00737	1.08e-89	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
HCPBGPIE_00739	6.38e-151	-	-	-	S	-	-	-	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
HCPBGPIE_00740	1.3e-65	azlD	-	-	E	-	-	-	Branched-chain amino acid transport
HCPBGPIE_00741	2.19e-153	azlC	-	-	E	-	-	-	azaleucine resistance protein AzlC
HCPBGPIE_00742	4.47e-74	-	-	-	K	-	-	-	Aminotransferase class I and II
HCPBGPIE_00743	2.78e-207	-	-	-	K	-	-	-	Aminotransferase class I and II
HCPBGPIE_00744	0.0	-	-	-	S	-	-	-	amidohydrolase
HCPBGPIE_00746	1.65e-206	-	-	-	S	-	-	-	reductase
HCPBGPIE_00747	4.4e-114	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase, GNAT family
HCPBGPIE_00748	2.44e-147	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HCPBGPIE_00749	7.33e-315	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
HCPBGPIE_00750	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HCPBGPIE_00751	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HCPBGPIE_00752	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HCPBGPIE_00753	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HCPBGPIE_00754	2.55e-169	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
HCPBGPIE_00755	2.96e-172	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HCPBGPIE_00756	1.39e-76	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HCPBGPIE_00757	7.96e-21	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
HCPBGPIE_00758	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HCPBGPIE_00759	1.41e-263	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HCPBGPIE_00760	1.97e-105	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
HCPBGPIE_00761	9.78e-14	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
HCPBGPIE_00762	5.41e-47	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
HCPBGPIE_00763	1.7e-261	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HCPBGPIE_00764	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HCPBGPIE_00765	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HCPBGPIE_00766	4.55e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HCPBGPIE_00767	5.93e-114	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HCPBGPIE_00768	9.36e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HCPBGPIE_00769	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HCPBGPIE_00770	1.25e-97	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HCPBGPIE_00771	6.04e-307	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HCPBGPIE_00772	5.34e-269	yttB	-	-	EGP	-	-	-	Major Facilitator
HCPBGPIE_00773	3.85e-72	-	-	-	-	-	-	-	-
HCPBGPIE_00774	6.22e-209	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
HCPBGPIE_00775	3.44e-12	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
HCPBGPIE_00778	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
HCPBGPIE_00779	1.85e-202	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HCPBGPIE_00782	1.55e-143	-	-	-	-	-	-	-	-
HCPBGPIE_00783	0.0	-	-	-	EGP	-	-	-	Major Facilitator
HCPBGPIE_00784	0.0	-	-	-	P	ko:K07085	-	ko00000	Predicted Permease Membrane Region
HCPBGPIE_00785	1.1e-171	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HCPBGPIE_00786	1.44e-164	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HCPBGPIE_00787	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HCPBGPIE_00788	6.42e-198	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HCPBGPIE_00789	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
HCPBGPIE_00790	5.75e-112	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HCPBGPIE_00792	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HCPBGPIE_00793	3.18e-236	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
HCPBGPIE_00794	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
HCPBGPIE_00795	3.04e-172	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HCPBGPIE_00796	6.27e-216	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HCPBGPIE_00797	4.28e-274	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HCPBGPIE_00798	9.62e-154	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HCPBGPIE_00799	5.84e-172	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HCPBGPIE_00800	3.51e-180	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HCPBGPIE_00801	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HCPBGPIE_00802	2.5e-162	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HCPBGPIE_00803	3.33e-66	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
HCPBGPIE_00804	1.1e-125	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
HCPBGPIE_00805	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HCPBGPIE_00806	5.12e-266	yacL	-	-	S	-	-	-	domain protein
HCPBGPIE_00807	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HCPBGPIE_00808	3.58e-93	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HCPBGPIE_00809	4.29e-174	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HCPBGPIE_00810	9.18e-31	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HCPBGPIE_00811	2.9e-31	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HCPBGPIE_00812	1.1e-126	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HCPBGPIE_00813	1.39e-92	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HCPBGPIE_00814	8.31e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HCPBGPIE_00815	1.86e-288	aadAT	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	Aminotransferase, class I
HCPBGPIE_00817	1.9e-313	-	-	-	M	-	-	-	Glycosyl transferase family group 2
HCPBGPIE_00818	1.99e-204	-	-	-	J	-	-	-	Methyltransferase
HCPBGPIE_00819	7.6e-28	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HCPBGPIE_00820	7.39e-217	-	-	-	S	-	-	-	PglZ domain
HCPBGPIE_00821	1.16e-64	doc	-	-	S	ko:K07341	-	ko00000,ko02048	Fic/DOC family
HCPBGPIE_00823	0.0	-	-	-	LV	-	-	-	Eco57I restriction-modification methylase
HCPBGPIE_00824	4.73e-258	-	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
HCPBGPIE_00825	3.59e-64	-	-	-	S	-	-	-	Domain of unknown function (DUF1788)
HCPBGPIE_00826	2.31e-56	-	-	-	S	-	-	-	Putative inner membrane protein (DUF1819)
HCPBGPIE_00827	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HCPBGPIE_00829	1.65e-286	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
HCPBGPIE_00830	3.39e-225	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HCPBGPIE_00831	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HCPBGPIE_00832	1.77e-202	-	-	-	EG	-	-	-	EamA-like transporter family
HCPBGPIE_00833	1.26e-44	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
HCPBGPIE_00834	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HCPBGPIE_00835	2.31e-148	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
HCPBGPIE_00836	1.92e-161	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
HCPBGPIE_00837	1.27e-291	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HCPBGPIE_00838	1.34e-47	-	-	-	S	-	-	-	Transglycosylase associated protein
HCPBGPIE_00839	6.08e-13	-	-	-	S	-	-	-	CsbD-like
HCPBGPIE_00840	1.44e-229	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HCPBGPIE_00841	3.1e-314	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
HCPBGPIE_00842	2.14e-123	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
HCPBGPIE_00843	6.09e-53	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
HCPBGPIE_00844	2.69e-192	-	-	-	-	-	-	-	-
HCPBGPIE_00845	6.02e-34	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
HCPBGPIE_00846	1.27e-108	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HCPBGPIE_00847	2.75e-132	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
HCPBGPIE_00848	3.59e-97	-	-	-	F	-	-	-	Nudix hydrolase
HCPBGPIE_00849	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
HCPBGPIE_00850	3.27e-243	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
HCPBGPIE_00851	8e-293	-	-	-	-	-	-	-	-
HCPBGPIE_00852	1.21e-266	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HCPBGPIE_00853	4.43e-183	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HCPBGPIE_00854	2.49e-187	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HCPBGPIE_00855	1.25e-262	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HCPBGPIE_00856	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HCPBGPIE_00857	8.65e-226	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HCPBGPIE_00858	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HCPBGPIE_00859	4.16e-112	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HCPBGPIE_00860	0.0	yagE	-	-	E	-	-	-	amino acid
HCPBGPIE_00861	9.45e-152	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
HCPBGPIE_00862	1.86e-62	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HCPBGPIE_00863	1.33e-162	-	-	-	L	-	-	-	Helix-turn-helix domain
HCPBGPIE_00864	5e-194	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HCPBGPIE_00865	1.39e-232	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HCPBGPIE_00866	5.46e-233	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
HCPBGPIE_00867	7.72e-178	-	-	-	IQ	-	-	-	KR domain
HCPBGPIE_00868	1.47e-171	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HCPBGPIE_00869	8.59e-127	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HCPBGPIE_00870	4.68e-314	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HCPBGPIE_00871	2.91e-147	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HCPBGPIE_00872	6.5e-71	-	-	-	-	-	-	-	-
HCPBGPIE_00873	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HCPBGPIE_00874	6.35e-69	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
HCPBGPIE_00875	2.53e-241	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HCPBGPIE_00876	1.3e-95	-	-	-	K	-	-	-	Transcriptional regulator
HCPBGPIE_00877	3.46e-207	-	-	-	-	-	-	-	-
HCPBGPIE_00878	1.62e-229	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HCPBGPIE_00879	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
HCPBGPIE_00880	1.37e-270	-	-	-	EGP	-	-	-	Major Facilitator
HCPBGPIE_00881	7.9e-176	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HCPBGPIE_00882	3.23e-45	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
HCPBGPIE_00883	1.08e-214	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
HCPBGPIE_00884	2.35e-211	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
HCPBGPIE_00885	3.67e-86	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HCPBGPIE_00886	1.95e-177	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HCPBGPIE_00887	1.35e-135	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HCPBGPIE_00888	1.67e-163	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HCPBGPIE_00889	2.65e-133	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HCPBGPIE_00890	7.6e-246	-	-	-	S	-	-	-	Helix-turn-helix domain
HCPBGPIE_00891	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HCPBGPIE_00892	2.15e-83	-	-	-	M	-	-	-	Lysin motif
HCPBGPIE_00893	3.8e-153	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HCPBGPIE_00894	1e-272	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HCPBGPIE_00895	0.0	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HCPBGPIE_00896	1.6e-54	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HCPBGPIE_00897	9.5e-301	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
HCPBGPIE_00898	4.94e-287	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HCPBGPIE_00899	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HCPBGPIE_00900	3.61e-247	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HCPBGPIE_00901	3.38e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HCPBGPIE_00902	2.59e-144	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
HCPBGPIE_00903	6.38e-196	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
HCPBGPIE_00904	4.79e-221	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HCPBGPIE_00905	4.05e-141	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
HCPBGPIE_00906	1.33e-47	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HCPBGPIE_00907	1.99e-204	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HCPBGPIE_00908	2.05e-180	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HCPBGPIE_00909	7.84e-207	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
HCPBGPIE_00910	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HCPBGPIE_00911	3.75e-210	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HCPBGPIE_00912	1.1e-138	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HCPBGPIE_00913	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HCPBGPIE_00914	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HCPBGPIE_00915	2.82e-110	-	-	-	F	-	-	-	NUDIX domain
HCPBGPIE_00916	5.18e-222	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
HCPBGPIE_00917	6.32e-275	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HCPBGPIE_00918	1.17e-61	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
HCPBGPIE_00919	3.86e-281	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HCPBGPIE_00920	4.61e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
HCPBGPIE_00921	2.57e-227	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
HCPBGPIE_00922	6.06e-308	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HCPBGPIE_00923	1.76e-45	ywzB	-	-	S	-	-	-	Protein of unknown function (DUF1146)
HCPBGPIE_00924	1.05e-88	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HCPBGPIE_00925	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HCPBGPIE_00926	1.3e-212	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HCPBGPIE_00927	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HCPBGPIE_00928	6.84e-121	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HCPBGPIE_00929	1.07e-95	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HCPBGPIE_00930	1.26e-29	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HCPBGPIE_00931	4.63e-162	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HCPBGPIE_00932	2.3e-293	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
HCPBGPIE_00933	4.71e-166	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
HCPBGPIE_00934	6.71e-246	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
HCPBGPIE_00935	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HCPBGPIE_00936	6.68e-150	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HCPBGPIE_00937	6.33e-294	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HCPBGPIE_00938	1.55e-250	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HCPBGPIE_00939	1.86e-208	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HCPBGPIE_00940	1.73e-248	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HCPBGPIE_00941	6.8e-140	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HCPBGPIE_00942	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain
HCPBGPIE_00943	4.87e-173	-	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
HCPBGPIE_00944	1.97e-297	potE	-	-	U	ko:K03756,ko:K03758	-	ko00000,ko02000	Amino acid permease
HCPBGPIE_00945	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
HCPBGPIE_00946	1.77e-103	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HCPBGPIE_00947	1.25e-304	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
HCPBGPIE_00948	9.5e-239	ampC	-	-	V	-	-	-	Beta-lactamase
HCPBGPIE_00949	2.01e-76	-	-	-	-	-	-	-	-
HCPBGPIE_00950	4.83e-215	-	-	-	M	-	-	-	domain protein
HCPBGPIE_00951	8.58e-223	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HCPBGPIE_00952	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HCPBGPIE_00953	3.82e-157	-	-	-	S	-	-	-	repeat protein
HCPBGPIE_00954	6.67e-158	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
HCPBGPIE_00955	2.15e-286	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HCPBGPIE_00956	1.13e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
HCPBGPIE_00957	1.75e-275	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HCPBGPIE_00958	1.97e-161	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HCPBGPIE_00959	1.54e-33	-	-	-	-	-	-	-	-
HCPBGPIE_00960	2.48e-129	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HCPBGPIE_00961	5.69e-44	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HCPBGPIE_00962	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HCPBGPIE_00963	3.71e-109	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
HCPBGPIE_00964	8.04e-185	ylmH	-	-	S	-	-	-	S4 domain protein
HCPBGPIE_00965	3.2e-54	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
HCPBGPIE_00966	1.11e-92	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HCPBGPIE_00967	6.52e-289	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HCPBGPIE_00968	0.0	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HCPBGPIE_00969	8.69e-195	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HCPBGPIE_00970	1.45e-260	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HCPBGPIE_00971	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HCPBGPIE_00972	7.73e-230	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HCPBGPIE_00973	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HCPBGPIE_00974	3.47e-73	ftsL	-	-	D	-	-	-	Cell division protein FtsL
HCPBGPIE_00975	9.31e-224	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HCPBGPIE_00976	1.5e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HCPBGPIE_00977	7.76e-74	-	-	-	-	-	-	-	-
HCPBGPIE_00978	4.47e-16	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
HCPBGPIE_00979	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HCPBGPIE_00980	1.53e-123	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HCPBGPIE_00981	8.5e-208	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
HCPBGPIE_00982	6.56e-252	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HCPBGPIE_00984	5.68e-95	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
HCPBGPIE_00985	4.76e-217	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
HCPBGPIE_00986	7.88e-215	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
HCPBGPIE_00987	1.53e-97	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HCPBGPIE_00988	1.05e-102	-	-	-	K	-	-	-	LytTr DNA-binding domain
HCPBGPIE_00989	1.2e-118	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HCPBGPIE_00990	5.18e-27	-	-	-	-	-	-	-	-
HCPBGPIE_00991	6.48e-153	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HCPBGPIE_00992	2.25e-105	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K07000,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
HCPBGPIE_00993	2.87e-250	-	-	-	S	-	-	-	Protein of unknown function (DUF3114)
HCPBGPIE_00994	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HCPBGPIE_00995	1.86e-213	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HCPBGPIE_00996	1.25e-136	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HCPBGPIE_00997	4.62e-81	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
HCPBGPIE_00998	5.34e-245	mocA	-	-	S	-	-	-	Oxidoreductase
HCPBGPIE_00999	4.3e-294	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
HCPBGPIE_01001	2.09e-266	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HCPBGPIE_01002	2.02e-72	-	-	-	-	-	-	-	-
HCPBGPIE_01003	4.94e-88	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
HCPBGPIE_01004	4.7e-103	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HCPBGPIE_01005	1e-215	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
HCPBGPIE_01006	3.98e-280	arcT	-	-	E	-	-	-	Aminotransferase
HCPBGPIE_01007	1.09e-170	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
HCPBGPIE_01008	2.36e-89	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
HCPBGPIE_01009	1.76e-09	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
HCPBGPIE_01010	0.0	potE	-	-	E	-	-	-	Amino Acid
HCPBGPIE_01011	7.47e-203	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HCPBGPIE_01012	1.26e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
HCPBGPIE_01013	2.53e-42	-	-	-	-	-	-	-	-
HCPBGPIE_01014	2.02e-175	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
HCPBGPIE_01015	1.84e-187	cps1D	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HCPBGPIE_01016	1.38e-225	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
HCPBGPIE_01017	1.15e-152	-	-	-	M	-	-	-	Bacterial sugar transferase
HCPBGPIE_01018	2.78e-275	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HCPBGPIE_01019	8.14e-303	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HCPBGPIE_01020	5.68e-190	-	-	GT4	M	ko:K02840	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Glycosyl transferases group 1
HCPBGPIE_01021	7.08e-168	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HCPBGPIE_01023	4.78e-222	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HCPBGPIE_01025	2.39e-253	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
HCPBGPIE_01026	0.0	pepD3	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HCPBGPIE_01027	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HCPBGPIE_01028	3.81e-274	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HCPBGPIE_01029	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HCPBGPIE_01030	5.24e-114	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HCPBGPIE_01031	1.13e-247	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HCPBGPIE_01032	1.79e-84	-	-	-	-	-	-	-	-
HCPBGPIE_01033	3.13e-225	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HCPBGPIE_01034	1.21e-215	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HCPBGPIE_01035	1.38e-77	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HCPBGPIE_01036	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HCPBGPIE_01037	1.96e-65	ylxQ	-	-	J	-	-	-	ribosomal protein
HCPBGPIE_01038	5.93e-60	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
HCPBGPIE_01039	1.68e-274	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HCPBGPIE_01040	1.1e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HCPBGPIE_01041	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HCPBGPIE_01042	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HCPBGPIE_01043	3.3e-298	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HCPBGPIE_01044	8.28e-178	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HCPBGPIE_01045	1.83e-182	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HCPBGPIE_01046	4.23e-123	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HCPBGPIE_01047	2.21e-167	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HCPBGPIE_01048	3.14e-197	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HCPBGPIE_01049	3.54e-184	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HCPBGPIE_01050	1.13e-70	-	-	-	K	-	-	-	LysR substrate binding domain
HCPBGPIE_01051	1.54e-78	-	-	-	K	-	-	-	LysR substrate binding domain
HCPBGPIE_01052	6.04e-220	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HCPBGPIE_01053	4.45e-315	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HCPBGPIE_01054	1.95e-220	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HCPBGPIE_01055	1.61e-166	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HCPBGPIE_01056	1.83e-148	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HCPBGPIE_01057	6.4e-149	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HCPBGPIE_01058	4.34e-121	ribB	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HCPBGPIE_01059	1.15e-301	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HCPBGPIE_01060	1.84e-223	ydbI	-	-	K	-	-	-	AI-2E family transporter
HCPBGPIE_01061	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HCPBGPIE_01062	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HCPBGPIE_01063	9.77e-170	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Belongs to the alpha-acetolactate decarboxylase family
HCPBGPIE_01064	3e-108	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HCPBGPIE_01065	1.61e-271	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HCPBGPIE_01066	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HCPBGPIE_01067	7.43e-170	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HCPBGPIE_01068	2.23e-50	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HCPBGPIE_01069	1.15e-162	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HCPBGPIE_01070	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HCPBGPIE_01071	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HCPBGPIE_01072	5.37e-248	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HCPBGPIE_01073	8.26e-136	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HCPBGPIE_01074	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HCPBGPIE_01075	4.57e-307	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HCPBGPIE_01076	5.27e-169	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HCPBGPIE_01077	7.38e-232	-	-	-	-	-	-	-	-
HCPBGPIE_01078	4.92e-305	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HCPBGPIE_01079	5.96e-139	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HCPBGPIE_01080	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HCPBGPIE_01081	2.48e-274	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HCPBGPIE_01082	5.83e-292	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HCPBGPIE_01083	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HCPBGPIE_01084	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
HCPBGPIE_01085	6.92e-236	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
HCPBGPIE_01086	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HCPBGPIE_01087	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HCPBGPIE_01088	1.22e-292	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HCPBGPIE_01089	1.23e-311	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HCPBGPIE_01090	6.98e-156	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
HCPBGPIE_01091	8.33e-230	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
HCPBGPIE_01092	4.46e-194	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HCPBGPIE_01093	1.62e-118	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
HCPBGPIE_01094	4.45e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HCPBGPIE_01095	1.51e-151	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HCPBGPIE_01096	4.04e-205	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HCPBGPIE_01097	2.13e-294	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
HCPBGPIE_01098	0.0	ymfH	-	-	S	-	-	-	Peptidase M16
HCPBGPIE_01099	2.06e-197	-	-	-	S	-	-	-	Helix-turn-helix domain
HCPBGPIE_01100	1.16e-133	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HCPBGPIE_01101	1.13e-289	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HCPBGPIE_01102	7.67e-252	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HCPBGPIE_01103	1.73e-221	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HCPBGPIE_01104	3.6e-107	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HCPBGPIE_01105	2.46e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HCPBGPIE_01106	2.77e-51	-	-	-	-	-	-	-	-
HCPBGPIE_01107	4.31e-180	-	-	-	L	-	-	-	Bacterial dnaA protein
HCPBGPIE_01108	2.56e-157	-	-	-	L	-	-	-	Integrase core domain
HCPBGPIE_01109	2.45e-65	-	-	-	L	-	-	-	Integrase core domain
HCPBGPIE_01111	2.94e-65	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HCPBGPIE_01112	2.79e-75	XK27_06915	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator PadR family
HCPBGPIE_01113	1.33e-127	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
HCPBGPIE_01114	3.1e-168	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
HCPBGPIE_01115	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HCPBGPIE_01116	4.63e-255	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HCPBGPIE_01117	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HCPBGPIE_01118	9.33e-48	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
HCPBGPIE_01119	6.21e-119	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HCPBGPIE_01120	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HCPBGPIE_01121	5.87e-62	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HCPBGPIE_01122	4.92e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HCPBGPIE_01123	4.67e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HCPBGPIE_01124	2.14e-147	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HCPBGPIE_01125	2.83e-69	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
HCPBGPIE_01126	2.23e-236	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HCPBGPIE_01127	3.71e-76	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HCPBGPIE_01128	3.7e-199	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HCPBGPIE_01129	6.09e-176	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HCPBGPIE_01130	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HCPBGPIE_01131	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HCPBGPIE_01132	3.23e-222	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HCPBGPIE_01133	1.48e-247	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HCPBGPIE_01134	1.02e-49	-	-	-	L	-	-	-	Transposase
HCPBGPIE_01136	4.51e-20	-	-	-	K	-	-	-	Helix-turn-helix domain
HCPBGPIE_01137	9.76e-25	-	-	-	K	-	-	-	Helix-turn-helix domain
HCPBGPIE_01140	9.32e-05	-	-	-	K	-	-	-	Helix-turn-helix domain
HCPBGPIE_01141	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HCPBGPIE_01142	3.27e-183	-	-	-	S	-	-	-	Putative ABC-transporter type IV
HCPBGPIE_01143	7.28e-138	-	-	-	NU	-	-	-	mannosyl-glycoprotein
HCPBGPIE_01144	1.8e-316	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HCPBGPIE_01145	6.07e-292	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
HCPBGPIE_01146	2.15e-261	yngD	-	-	S	ko:K07097	-	ko00000	DHHA1 domain
HCPBGPIE_01148	5.87e-65	-	-	-	-	-	-	-	-
HCPBGPIE_01149	1.62e-34	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HCPBGPIE_01150	6.88e-132	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HCPBGPIE_01152	2.84e-73	-	-	-	-	-	-	-	-
HCPBGPIE_01153	7.94e-150	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
HCPBGPIE_01155	3.47e-85	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
HCPBGPIE_01156	1.92e-153	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HCPBGPIE_01157	1.46e-261	-	-	-	S	-	-	-	associated with various cellular activities
HCPBGPIE_01158	2.66e-307	-	-	-	S	-	-	-	Putative metallopeptidase domain
HCPBGPIE_01159	4.95e-63	-	-	-	-	-	-	-	-
HCPBGPIE_01160	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HCPBGPIE_01161	2.13e-142	-	-	-	K	-	-	-	Helix-turn-helix domain
HCPBGPIE_01162	2.18e-115	ymdB	-	-	S	-	-	-	Macro domain protein
HCPBGPIE_01163	7.33e-253	-	-	-	EGP	-	-	-	Major Facilitator
HCPBGPIE_01164	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HCPBGPIE_01165	4.05e-70	-	-	-	S	-	-	-	branched-chain amino acid
HCPBGPIE_01166	4.95e-195	-	-	-	E	-	-	-	AzlC protein
HCPBGPIE_01167	5.47e-261	hpk31	-	-	T	-	-	-	Histidine kinase
HCPBGPIE_01168	3.27e-159	vanR	-	-	K	-	-	-	response regulator
HCPBGPIE_01169	8.13e-263	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HCPBGPIE_01170	1.32e-219	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	sugar-binding domain protein
HCPBGPIE_01171	3.27e-167	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
HCPBGPIE_01172	2.15e-298	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
HCPBGPIE_01173	1.09e-296	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HCPBGPIE_01174	9.74e-154	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HCPBGPIE_01175	4.25e-173	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
HCPBGPIE_01176	6.1e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HCPBGPIE_01177	5.8e-43	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
HCPBGPIE_01178	4.83e-198	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HCPBGPIE_01179	2.79e-178	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
HCPBGPIE_01180	3.73e-200	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HCPBGPIE_01181	6.29e-163	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HCPBGPIE_01182	1.2e-207	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
HCPBGPIE_01183	2.76e-217	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
HCPBGPIE_01184	3.42e-278	nupG	-	-	F	ko:K03317,ko:K11535,ko:K16323	-	ko00000,ko02000	Nucleoside transporter
HCPBGPIE_01185	1.77e-285	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HCPBGPIE_01187	5.67e-178	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HCPBGPIE_01188	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HCPBGPIE_01189	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HCPBGPIE_01190	8.03e-58	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HCPBGPIE_01191	3.62e-100	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HCPBGPIE_01192	3.75e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HCPBGPIE_01193	8.35e-121	cvpA	-	-	S	-	-	-	Colicin V production protein
HCPBGPIE_01194	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HCPBGPIE_01195	2.86e-72	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HCPBGPIE_01196	1.01e-124	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HCPBGPIE_01197	2.58e-184	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HCPBGPIE_01198	3.33e-133	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HCPBGPIE_01199	9.81e-122	-	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HCPBGPIE_01200	3.62e-100	ykuL	-	-	S	-	-	-	(CBS) domain
HCPBGPIE_01201	1.1e-195	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HCPBGPIE_01202	6.23e-188	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
HCPBGPIE_01203	2.09e-69	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HCPBGPIE_01204	1.84e-75	-	-	-	-	-	-	-	-
HCPBGPIE_01205	4.4e-269	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HCPBGPIE_01206	3.28e-233	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HCPBGPIE_01207	1.15e-178	-	-	-	-	-	-	-	-
HCPBGPIE_01208	1.22e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
HCPBGPIE_01209	4.67e-232	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
HCPBGPIE_01210	2.49e-232	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
HCPBGPIE_01211	6.31e-62	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
HCPBGPIE_01212	1.01e-100	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
HCPBGPIE_01213	1.61e-54	-	-	-	-	-	-	-	-
HCPBGPIE_01214	9.32e-92	-	-	-	-	ko:K02248	-	ko00000,ko00002,ko02044	-
HCPBGPIE_01216	2.07e-185	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
HCPBGPIE_01217	4.18e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HCPBGPIE_01218	1.08e-146	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HCPBGPIE_01219	9.28e-121	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
HCPBGPIE_01220	2.87e-171	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HCPBGPIE_01221	1.03e-135	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
HCPBGPIE_01222	1.83e-149	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
HCPBGPIE_01223	1.14e-152	-	-	-	I	-	-	-	phosphatase
HCPBGPIE_01225	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
HCPBGPIE_01226	7.78e-150	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HCPBGPIE_01232	3.77e-120	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
HCPBGPIE_01233	4.62e-21	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
HCPBGPIE_01234	8.94e-250	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HCPBGPIE_01235	1.39e-101	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
HCPBGPIE_01236	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HCPBGPIE_01237	2.09e-143	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HCPBGPIE_01238	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HCPBGPIE_01239	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HCPBGPIE_01240	1.15e-263	-	-	-	-	-	-	-	-
HCPBGPIE_01241	1.14e-152	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
HCPBGPIE_01242	2.51e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HCPBGPIE_01243	2.06e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HCPBGPIE_01244	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HCPBGPIE_01245	5.84e-160	-	-	-	-	-	-	-	-
HCPBGPIE_01246	2.84e-73	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
HCPBGPIE_01247	0.0	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
HCPBGPIE_01249	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
HCPBGPIE_01250	2.72e-102	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	PAP2 superfamily
HCPBGPIE_01251	4.45e-226	ydhF	-	-	S	-	-	-	Aldo keto reductase
HCPBGPIE_01253	8.69e-182	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HCPBGPIE_01254	1.26e-82	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
HCPBGPIE_01255	1.24e-132	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
HCPBGPIE_01257	3.97e-232	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HCPBGPIE_01258	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HCPBGPIE_01259	2.3e-52	-	-	-	S	-	-	-	Cytochrome b5-like Heme/Steroid binding domain
HCPBGPIE_01260	1.63e-148	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HCPBGPIE_01261	3.88e-50	-	-	-	-	-	-	-	-
HCPBGPIE_01262	2.47e-167	-	-	-	IQ	-	-	-	dehydrogenase reductase
HCPBGPIE_01263	2.03e-307	-	-	-	EGP	-	-	-	MFS transporter, metabolite H symporter (MHS) family protein
HCPBGPIE_01264	8.85e-147	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HCPBGPIE_01269	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HCPBGPIE_01270	3.51e-253	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
HCPBGPIE_01271	5.35e-121	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HCPBGPIE_01272	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
HCPBGPIE_01273	4.15e-145	-	-	-	GM	-	-	-	NAD dependent epimerase dehydratase family protein
HCPBGPIE_01274	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
HCPBGPIE_01275	7.6e-269	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HCPBGPIE_01276	1.61e-291	-	-	-	-	-	-	-	-
HCPBGPIE_01277	6.71e-102	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HCPBGPIE_01278	2.74e-139	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
HCPBGPIE_01279	2.74e-69	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HCPBGPIE_01280	7.48e-155	-	-	-	GM	-	-	-	NmrA-like family
HCPBGPIE_01281	5.36e-92	-	-	-	S	ko:K02348	-	ko00000	Gnat family
HCPBGPIE_01282	2.3e-52	-	-	-	S	-	-	-	Cytochrome B5
HCPBGPIE_01283	8.47e-08	-	-	-	S	-	-	-	Cytochrome B5
HCPBGPIE_01284	4.51e-54	-	-	-	S	-	-	-	Cytochrome B5
HCPBGPIE_01285	4.77e-270	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
HCPBGPIE_01287	1.63e-233	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HCPBGPIE_01288	4.9e-315	-	-	-	E	ko:K03294	-	ko00000	amino acid
HCPBGPIE_01289	6.2e-271	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
HCPBGPIE_01290	8.57e-289	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
HCPBGPIE_01292	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HCPBGPIE_01293	2.18e-79	-	-	-	-	-	-	-	-
HCPBGPIE_01294	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HCPBGPIE_01295	7.01e-244	-	-	-	E	-	-	-	Zinc-binding dehydrogenase
HCPBGPIE_01296	2.72e-113	-	-	-	K	-	-	-	transcriptional regulator (TetR family)
HCPBGPIE_01297	2.39e-234	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HCPBGPIE_01298	4.22e-148	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HCPBGPIE_01299	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HCPBGPIE_01300	1.18e-50	-	-	-	-	-	-	-	-
HCPBGPIE_01301	4.57e-65	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
HCPBGPIE_01302	3.32e-310	-	3.2.1.17	CBM50	NU	ko:K01185,ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HCPBGPIE_01303	3.11e-220	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
HCPBGPIE_01304	2.14e-32	-	-	-	-	-	-	-	-
HCPBGPIE_01305	1.03e-146	-	-	-	-	-	-	-	-
HCPBGPIE_01306	4.99e-273	yttB	-	-	EGP	-	-	-	Major Facilitator
HCPBGPIE_01307	6.55e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HCPBGPIE_01308	8.23e-112	-	-	-	-	-	-	-	-
HCPBGPIE_01309	4.3e-142	nnrE	5.1.99.6	-	H	ko:K17759	-	ko00000,ko01000	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
HCPBGPIE_01310	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HCPBGPIE_01311	1.2e-76	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
HCPBGPIE_01312	3.82e-215	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
HCPBGPIE_01313	1.24e-172	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HCPBGPIE_01314	1.18e-229	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HCPBGPIE_01315	1.89e-19	-	-	-	G	ko:K03832	-	ko00000,ko02000	Belongs to the glycosyl hydrolase family 6
HCPBGPIE_01316	2.72e-82	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
HCPBGPIE_01317	1.48e-290	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HCPBGPIE_01318	2.66e-114	-	-	-	Q	-	-	-	Methyltransferase
HCPBGPIE_01319	1.14e-151	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
HCPBGPIE_01320	3.91e-304	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
HCPBGPIE_01321	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
HCPBGPIE_01322	1.3e-57	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
HCPBGPIE_01323	3.99e-91	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
HCPBGPIE_01324	1.29e-279	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
HCPBGPIE_01325	3.82e-310	-	-	-	M	-	-	-	Glycosyl transferase
HCPBGPIE_01326	3.14e-195	-	-	-	-	-	-	-	-
HCPBGPIE_01327	3.52e-161	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HCPBGPIE_01328	1.82e-176	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HCPBGPIE_01329	2.03e-194	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
HCPBGPIE_01330	1.31e-193	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HCPBGPIE_01331	1.99e-204	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HCPBGPIE_01332	8.38e-170	-	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C-terminal domain protein
HCPBGPIE_01333	5.21e-191	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HCPBGPIE_01334	2.7e-155	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HCPBGPIE_01335	6.98e-137	-	-	-	L	-	-	-	Helix-turn-helix domain
HCPBGPIE_01336	0.0	araP	-	-	U	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HCPBGPIE_01337	0.0	araB	2.7.1.16	-	G	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	carbohydrate kinase FGGY
HCPBGPIE_01338	1.91e-178	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HCPBGPIE_01339	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
HCPBGPIE_01340	3.47e-123	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
HCPBGPIE_01341	3.44e-200	yvgN	-	-	S	-	-	-	Aldo keto reductase
HCPBGPIE_01342	8.8e-264	araR	-	-	K	ko:K02103	-	ko00000,ko03000	Transcriptional regulator
HCPBGPIE_01343	1.95e-109	uspA	-	-	T	-	-	-	universal stress protein
HCPBGPIE_01344	3.61e-61	-	-	-	-	-	-	-	-
HCPBGPIE_01345	1.88e-309	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HCPBGPIE_01346	2.03e-111	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HCPBGPIE_01347	9.79e-29	-	-	-	-	-	-	-	-
HCPBGPIE_01348	2e-98	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase
HCPBGPIE_01349	4.16e-180	-	-	-	S	-	-	-	Membrane
HCPBGPIE_01350	3.89e-172	-	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
HCPBGPIE_01351	0.0	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HCPBGPIE_01352	0.0	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HCPBGPIE_01354	4.17e-174	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HCPBGPIE_01355	5.75e-242	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HCPBGPIE_01356	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HCPBGPIE_01357	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HCPBGPIE_01358	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HCPBGPIE_01359	1.65e-113	ebsC	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HCPBGPIE_01360	3.02e-171	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
HCPBGPIE_01361	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HCPBGPIE_01362	1.05e-310	-	-	-	E	-	-	-	amino acid
HCPBGPIE_01363	4.49e-180	yfhR3	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
HCPBGPIE_01364	9.75e-311	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HCPBGPIE_01365	2.17e-213	-	-	-	GK	-	-	-	ROK family
HCPBGPIE_01366	0.0	fusA1	-	-	J	-	-	-	elongation factor G
HCPBGPIE_01367	7.46e-106	uspA3	-	-	T	-	-	-	universal stress protein
HCPBGPIE_01368	1.42e-248	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HCPBGPIE_01369	1.78e-83	-	-	-	-	-	-	-	-
HCPBGPIE_01370	3.18e-11	-	-	-	-	-	-	-	-
HCPBGPIE_01371	1.12e-236	-	2.1.1.72, 3.1.21.3	AA10,CBM73	M	ko:K01154,ko:K02014,ko:K03933,ko:K07316	-	ko00000,ko01000,ko02000,ko02048	domain protein
HCPBGPIE_01372	0.0	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HCPBGPIE_01373	2.32e-233	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
HCPBGPIE_01374	1.21e-213	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HCPBGPIE_01375	3.23e-75	-	-	-	S	-	-	-	Small secreted protein
HCPBGPIE_01376	2.95e-75	ytpP	-	-	CO	-	-	-	Thioredoxin
HCPBGPIE_01377	1.63e-152	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HCPBGPIE_01378	7.39e-64	-	-	-	S	-	-	-	Bacterial toxin of type II toxin-antitoxin system, YafQ
HCPBGPIE_01379	9.47e-48	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
HCPBGPIE_01380	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HCPBGPIE_01381	6.48e-154	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HCPBGPIE_01382	5.63e-151	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
HCPBGPIE_01383	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HCPBGPIE_01384	2.74e-204	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HCPBGPIE_01385	5.91e-129	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HCPBGPIE_01386	2.82e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HCPBGPIE_01387	3.31e-275	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
HCPBGPIE_01388	2.76e-218	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HCPBGPIE_01389	1.07e-110	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HCPBGPIE_01390	1.82e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HCPBGPIE_01391	2.23e-73	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HCPBGPIE_01392	1.59e-93	-	-	-	K	-	-	-	Putative DNA-binding domain
HCPBGPIE_01393	2.23e-156	-	-	-	-	-	-	-	-
HCPBGPIE_01394	2.07e-197	nlaXM	2.1.1.37	-	H	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	cytosine-specific methyltransferase
HCPBGPIE_01395	3.13e-64	vsr	-	-	L	ko:K07458	-	ko00000,ko01000,ko03400	DNA mismatch endonuclease Vsr
HCPBGPIE_01400	9.41e-106	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HCPBGPIE_01401	1.36e-47	-	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
HCPBGPIE_01402	4.61e-128	nicK	-	-	L	ko:K07467	-	ko00000	Replication initiation factor
HCPBGPIE_01404	1.99e-66	-	-	-	L	-	-	-	Lactococcus lactis RepB C-terminus
HCPBGPIE_01405	7.13e-119	-	-	-	L	-	-	-	Integrase
HCPBGPIE_01407	1.54e-49	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HCPBGPIE_01408	8.58e-185	-	-	-	F	ko:K10974	-	ko00000,ko02000	Permease for cytosine/purines, uracil, thiamine, allantoin
HCPBGPIE_01409	1.15e-160	-	-	-	S	ko:K09703	-	ko00000	Protein of unknown function (DUF917)
HCPBGPIE_01410	1.67e-230	apc3	-	-	EQ	-	-	-	Hydantoinase/oxoprolinase N-terminal region
HCPBGPIE_01411	1.28e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HCPBGPIE_01412	5.45e-153	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HCPBGPIE_01413	6.64e-139	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HCPBGPIE_01414	3.61e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HCPBGPIE_01415	1.16e-203	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HCPBGPIE_01416	5.72e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HCPBGPIE_01417	8.8e-70	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HCPBGPIE_01418	9.81e-157	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HCPBGPIE_01419	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HCPBGPIE_01420	5.49e-38	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HCPBGPIE_01421	1.1e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HCPBGPIE_01422	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HCPBGPIE_01423	2.58e-65	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HCPBGPIE_01424	7.42e-125	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HCPBGPIE_01425	1.54e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HCPBGPIE_01426	2.6e-124	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HCPBGPIE_01427	5.03e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HCPBGPIE_01428	1.2e-111	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HCPBGPIE_01429	5.94e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HCPBGPIE_01430	6.05e-93	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HCPBGPIE_01431	2.88e-306	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HCPBGPIE_01432	4.52e-161	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HCPBGPIE_01433	9.82e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HCPBGPIE_01434	5.79e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
HCPBGPIE_01435	1.54e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HCPBGPIE_01436	1.62e-83	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HCPBGPIE_01437	8.91e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HCPBGPIE_01438	8.08e-83	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HCPBGPIE_01439	1.23e-186	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HCPBGPIE_01440	9.73e-195	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HCPBGPIE_01441	1.43e-181	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HCPBGPIE_01442	6.12e-182	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HCPBGPIE_01443	9.25e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HCPBGPIE_01444	3.94e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HCPBGPIE_01450	5.79e-217	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HCPBGPIE_01451	3.25e-33	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NLP P60 protein
HCPBGPIE_01452	3.93e-159	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HCPBGPIE_01453	8.75e-92	-	-	-	L	-	-	-	Helix-turn-helix domain
HCPBGPIE_01454	6.55e-216	ganB	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
HCPBGPIE_01455	9.84e-83	-	-	-	S	-	-	-	dextransucrase activity
HCPBGPIE_01457	1.31e-130	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HCPBGPIE_01459	1.27e-147	-	-	-	L	-	-	-	Helix-turn-helix domain
HCPBGPIE_01460	1.13e-154	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HCPBGPIE_01461	1.87e-100	-	-	-	S	-	-	-	KAP family P-loop domain
HCPBGPIE_01462	8.25e-149	-	-	-	M	-	-	-	PFAM NLP P60 protein
HCPBGPIE_01463	3.16e-233	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HCPBGPIE_01464	5.58e-195	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HCPBGPIE_01465	5.63e-177	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HCPBGPIE_01466	1.12e-118	-	-	-	P	-	-	-	Cadmium resistance transporter
HCPBGPIE_01467	1.14e-74	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
HCPBGPIE_01468	1.84e-45	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HCPBGPIE_01469	1.7e-299	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
HCPBGPIE_01470	4.38e-72	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HCPBGPIE_01471	3.78e-169	yceF	-	-	P	ko:K05794	-	ko00000	membrane
HCPBGPIE_01472	8.16e-212	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HCPBGPIE_01473	2.35e-215	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HCPBGPIE_01474	2.36e-54	-	-	-	L	-	-	-	Transposase
HCPBGPIE_01475	3.25e-60	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HCPBGPIE_01476	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HCPBGPIE_01477	1.69e-235	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
HCPBGPIE_01478	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HCPBGPIE_01479	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HCPBGPIE_01480	3.22e-65	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HCPBGPIE_01481	1.11e-260	camS	-	-	S	-	-	-	sex pheromone
HCPBGPIE_01482	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HCPBGPIE_01483	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HCPBGPIE_01484	8.91e-270	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HCPBGPIE_01485	3.91e-130	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HCPBGPIE_01486	3.07e-149	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
HCPBGPIE_01487	4.46e-180	budC	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
HCPBGPIE_01488	6.1e-85	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
HCPBGPIE_01490	1.09e-272	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HCPBGPIE_01492	1.36e-33	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HCPBGPIE_01493	3.85e-71	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HCPBGPIE_01494	4.3e-111	-	-	-	M	-	-	-	Stealth protein CR2, conserved region 2
HCPBGPIE_01495	8.22e-113	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HCPBGPIE_01496	7.89e-118	-	-	-	M	-	-	-	Glycosyl transferases group 1
HCPBGPIE_01497	2.86e-156	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HCPBGPIE_01498	1.22e-67	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
HCPBGPIE_01499	6.24e-45	-	-	-	S	-	-	-	Glycosyltransferase family 28 C-terminal domain
HCPBGPIE_01500	1.05e-46	-	-	-	M	-	-	-	Oligosaccharide biosynthesis protein Alg14 like
HCPBGPIE_01501	2.74e-59	-	-	-	-	-	-	-	-
HCPBGPIE_01502	1.12e-121	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
HCPBGPIE_01503	6.05e-153	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HCPBGPIE_01504	2.87e-175	epsB	-	-	M	-	-	-	biosynthesis protein
HCPBGPIE_01505	9.74e-213	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HCPBGPIE_01506	8.92e-87	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HCPBGPIE_01507	1.7e-118	-	-	-	-	-	-	-	-
HCPBGPIE_01508	5.27e-162	XK27_10500	-	-	K	-	-	-	response regulator
HCPBGPIE_01509	7.23e-202	yvgN	-	-	S	-	-	-	Aldo keto reductase
HCPBGPIE_01510	9.74e-176	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HCPBGPIE_01511	4.74e-107	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HCPBGPIE_01512	2.24e-261	-	-	-	-	-	-	-	-
HCPBGPIE_01513	1.24e-68	-	-	-	-	-	-	-	-
HCPBGPIE_01514	1.21e-48	-	-	-	-	-	-	-	-
HCPBGPIE_01515	5.55e-121	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HCPBGPIE_01516	5.69e-189	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HCPBGPIE_01517	1.34e-234	celE3	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HCPBGPIE_01518	8.5e-287	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HCPBGPIE_01519	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HCPBGPIE_01520	1.97e-231	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HCPBGPIE_01521	7.33e-133	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
HCPBGPIE_01522	8.33e-294	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HCPBGPIE_01523	2.7e-104	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
HCPBGPIE_01524	2.71e-103	usp5	-	-	T	-	-	-	universal stress protein
HCPBGPIE_01525	9.42e-57	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
HCPBGPIE_01527	1.12e-135	-	-	-	K	-	-	-	PFAM GCN5-related N-acetyltransferase
HCPBGPIE_01528	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HCPBGPIE_01529	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HCPBGPIE_01530	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HCPBGPIE_01531	5.18e-222	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
HCPBGPIE_01532	7.36e-272	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
HCPBGPIE_01534	3.1e-246	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HCPBGPIE_01535	6.21e-266	secY2	-	-	U	-	-	-	Part of the accessory SecA2 SecY2 system specifically required for export of
HCPBGPIE_01536	0.0	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HCPBGPIE_01537	0.0	asp2	-	-	S	ko:K12269	-	ko00000,ko02044	Accessory Sec system GspB-transporter
HCPBGPIE_01538	1.85e-207	asp3	-	-	S	ko:K12270	-	ko00000,ko02044	Accessory Sec secretory system ASP3
HCPBGPIE_01539	0.0	secA2	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HCPBGPIE_01540	1.92e-284	gtf1	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HCPBGPIE_01541	2.98e-248	gtf2	-	-	M	-	-	-	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
HCPBGPIE_01545	2.09e-265	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HCPBGPIE_01546	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HCPBGPIE_01547	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HCPBGPIE_01548	2.14e-234	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HCPBGPIE_01549	2.14e-189	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HCPBGPIE_01550	1.08e-218	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HCPBGPIE_01551	2.11e-80	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
HCPBGPIE_01552	1.55e-109	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HCPBGPIE_01553	2.6e-234	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
HCPBGPIE_01554	4.11e-225	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HCPBGPIE_01555	1.71e-119	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HCPBGPIE_01556	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HCPBGPIE_01557	5.19e-199	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HCPBGPIE_01558	6.45e-49	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HCPBGPIE_01559	6.91e-234	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HCPBGPIE_01560	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HCPBGPIE_01561	4.79e-307	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
HCPBGPIE_01562	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HCPBGPIE_01563	1.62e-303	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
HCPBGPIE_01564	3.39e-33	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
HCPBGPIE_01565	3.18e-160	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
HCPBGPIE_01566	1.77e-56	-	-	-	-	-	-	-	-
HCPBGPIE_01567	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HCPBGPIE_01568	2.84e-264	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	dehydrogenase
HCPBGPIE_01569	2.56e-188	-	-	-	S	-	-	-	Alpha beta hydrolase
HCPBGPIE_01570	1.02e-279	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HCPBGPIE_01571	4.75e-132	-	-	-	-	-	-	-	-
HCPBGPIE_01573	5.09e-162	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HCPBGPIE_01574	2.29e-276	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HCPBGPIE_01575	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HCPBGPIE_01576	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HCPBGPIE_01577	1.51e-131	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HCPBGPIE_01578	2.86e-244	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HCPBGPIE_01579	1.25e-241	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HCPBGPIE_01580	7.54e-62	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HCPBGPIE_01581	6.15e-234	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
HCPBGPIE_01582	0.0	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HCPBGPIE_01583	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HCPBGPIE_01584	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HCPBGPIE_01585	1.32e-218	-	-	-	S	-	-	-	Protein of unknown function DUF262
HCPBGPIE_01586	2.75e-105	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
HCPBGPIE_01587	1.26e-60	-	-	-	-	-	-	-	-
HCPBGPIE_01588	2.58e-41	-	-	-	-	-	-	-	-
HCPBGPIE_01589	1.09e-62	-	-	-	-	-	-	-	-
HCPBGPIE_01590	5.91e-125	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HCPBGPIE_01591	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HCPBGPIE_01592	1.89e-295	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
HCPBGPIE_01593	3.99e-233	-	-	-	K	ko:K02525	-	ko00000,ko03000	Transcriptional regulator, LacI family
HCPBGPIE_01594	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HCPBGPIE_01595	2.3e-124	-	-	-	-	-	-	-	-
HCPBGPIE_01596	3.09e-35	-	-	-	-	-	-	-	-
HCPBGPIE_01597	2.71e-81	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HCPBGPIE_01598	1.42e-112	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HCPBGPIE_01600	2.16e-64	-	-	-	-	-	-	-	-
HCPBGPIE_01601	6.1e-88	-	-	-	S	-	-	-	Belongs to the HesB IscA family
HCPBGPIE_01603	3.21e-40	-	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
HCPBGPIE_01604	1.81e-26	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NLP P60 protein
HCPBGPIE_01607	7.77e-159	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HCPBGPIE_01608	2.88e-270	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
HCPBGPIE_01609	4.18e-147	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HCPBGPIE_01610	2.7e-47	ynzC	-	-	S	-	-	-	UPF0291 protein
HCPBGPIE_01611	1.6e-40	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
HCPBGPIE_01612	7.51e-152	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
HCPBGPIE_01613	5.9e-182	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
HCPBGPIE_01614	6.79e-65	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
HCPBGPIE_01615	1.25e-233	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HCPBGPIE_01616	1.92e-202	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HCPBGPIE_01617	1.32e-236	XK27_12525	-	-	S	-	-	-	AI-2E family transporter
HCPBGPIE_01618	7.74e-173	XK27_07210	-	-	S	-	-	-	B3 4 domain
HCPBGPIE_01619	8.16e-103	yybA	-	-	K	-	-	-	Transcriptional regulator
HCPBGPIE_01620	5.25e-118	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HCPBGPIE_01621	3.16e-114	-	-	-	GM	-	-	-	epimerase
HCPBGPIE_01622	1.39e-198	-	-	-	V	-	-	-	(ABC) transporter
HCPBGPIE_01623	1.37e-306	yhdP	-	-	S	-	-	-	Transporter associated domain
HCPBGPIE_01624	1.98e-110	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
HCPBGPIE_01625	3.68e-97	-	-	-	S	ko:K04750	-	ko00000	3-demethylubiquinone-9 3-methyltransferase
HCPBGPIE_01626	2.64e-246	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
HCPBGPIE_01627	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HCPBGPIE_01628	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HCPBGPIE_01629	3.91e-40	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HCPBGPIE_01630	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HCPBGPIE_01631	1.72e-222	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HCPBGPIE_01632	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
HCPBGPIE_01633	6.57e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Peroxiredoxin
HCPBGPIE_01634	5.11e-188	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HCPBGPIE_01635	1.76e-154	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
HCPBGPIE_01638	2.48e-57	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HCPBGPIE_01639	4.36e-90	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	Toxin-antitoxin system, toxin component, MazF family
HCPBGPIE_01640	2.74e-50	-	-	-	-	ko:K18829	-	ko00000,ko02048	-
HCPBGPIE_01642	0.0	snf	-	-	KL	-	-	-	domain protein
HCPBGPIE_01643	2.71e-186	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
HCPBGPIE_01644	2.63e-226	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HCPBGPIE_01645	1.12e-265	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HCPBGPIE_01646	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
HCPBGPIE_01648	7.54e-115	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HCPBGPIE_01649	1.49e-225	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HCPBGPIE_01650	5.79e-117	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
HCPBGPIE_01651	1.84e-282	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
HCPBGPIE_01652	2.52e-196	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
HCPBGPIE_01653	3.39e-191	yycI	-	-	S	-	-	-	YycH protein
HCPBGPIE_01654	2.41e-315	yycH	-	-	S	-	-	-	YycH protein
HCPBGPIE_01655	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HCPBGPIE_01656	3.69e-168	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HCPBGPIE_01658	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HCPBGPIE_01659	6.55e-97	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
HCPBGPIE_01665	7.89e-168	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
HCPBGPIE_01666	1.55e-176	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
HCPBGPIE_01667	2.41e-183	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HCPBGPIE_01668	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
HCPBGPIE_01669	4.61e-97	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HCPBGPIE_01670	6.2e-96	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HCPBGPIE_01671	1.21e-286	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HCPBGPIE_01672	1.05e-167	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HCPBGPIE_01673	3.95e-203	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
HCPBGPIE_01674	2.51e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HCPBGPIE_01675	1.33e-226	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HCPBGPIE_01676	2.35e-101	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HCPBGPIE_01677	1.76e-94	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HCPBGPIE_01679	3.82e-255	xerS	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HCPBGPIE_01680	2.34e-92	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
HCPBGPIE_01681	8.25e-31	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HCPBGPIE_01682	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HCPBGPIE_01683	6.06e-168	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HCPBGPIE_01684	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HCPBGPIE_01685	2.09e-211	-	-	-	G	-	-	-	Phosphotransferase enzyme family
HCPBGPIE_01686	1.88e-101	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HCPBGPIE_01687	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HCPBGPIE_01688	4.8e-72	-	-	-	-	-	-	-	-
HCPBGPIE_01689	1.66e-165	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HCPBGPIE_01690	2.69e-228	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
HCPBGPIE_01691	7.92e-76	-	-	-	-	-	-	-	-
HCPBGPIE_01692	7.41e-114	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
HCPBGPIE_01693	8.09e-44	-	-	-	S	ko:K06889	-	ko00000	thiolester hydrolase activity
HCPBGPIE_01694	2.05e-195	-	-	-	S	-	-	-	Alpha beta hydrolase
HCPBGPIE_01695	2.49e-120	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
HCPBGPIE_01696	1.02e-120	-	-	-	K	-	-	-	Virulence activator alpha C-term
HCPBGPIE_01697	1.39e-83	-	-	-	GM	-	-	-	NAD(P)H-binding
HCPBGPIE_01698	1.45e-214	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
HCPBGPIE_01699	5.69e-235	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
HCPBGPIE_01700	5.61e-75	-	-	-	K	-	-	-	Transcriptional regulator
HCPBGPIE_01701	3.02e-52	-	-	-	K	-	-	-	Transcriptional regulator
HCPBGPIE_01702	3.06e-121	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HCPBGPIE_01703	6.78e-136	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
HCPBGPIE_01704	1.28e-105	-	-	-	S	-	-	-	membrane
HCPBGPIE_01705	3.43e-110	-	-	-	S	-	-	-	membrane
HCPBGPIE_01706	2.22e-145	-	-	-	GM	-	-	-	NAD(P)H-binding
HCPBGPIE_01707	2.03e-84	-	-	-	-	-	-	-	-
HCPBGPIE_01708	4.18e-168	-	-	-	F	-	-	-	glutamine amidotransferase
HCPBGPIE_01709	7.99e-293	-	-	-	V	-	-	-	MatE
HCPBGPIE_01710	9.16e-91	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HCPBGPIE_01711	3.89e-215	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HCPBGPIE_01712	1.79e-60	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HCPBGPIE_01713	2.22e-185	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HCPBGPIE_01714	3.75e-119	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HCPBGPIE_01715	2.36e-77	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HCPBGPIE_01716	2.12e-251	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HCPBGPIE_01717	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HCPBGPIE_01718	5.69e-147	-	-	-	M	-	-	-	PFAM NLP P60 protein
HCPBGPIE_01719	2.06e-152	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HCPBGPIE_01720	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
HCPBGPIE_01721	4.85e-232	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HCPBGPIE_01722	6.98e-286	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HCPBGPIE_01723	1.82e-181	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
HCPBGPIE_01724	3.49e-175	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HCPBGPIE_01725	6.3e-291	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HCPBGPIE_01726	5.14e-170	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HCPBGPIE_01727	2.12e-253	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HCPBGPIE_01728	1.01e-133	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
HCPBGPIE_01729	1.96e-166	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
HCPBGPIE_01730	1.91e-126	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HCPBGPIE_01731	4.29e-314	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HCPBGPIE_01732	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Type I restriction enzyme R protein N terminus (HSDR_N)
HCPBGPIE_01735	3.43e-65	-	-	-	-	-	-	-	-
HCPBGPIE_01737	5.65e-143	-	-	-	I	-	-	-	Acid phosphatase homologues
HCPBGPIE_01738	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
HCPBGPIE_01739	2.78e-292	-	-	-	P	-	-	-	Chloride transporter, ClC family
HCPBGPIE_01740	1.24e-147	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HCPBGPIE_01741	8.69e-190	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HCPBGPIE_01742	1.87e-178	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HCPBGPIE_01743	1.44e-66	-	-	-	-	-	-	-	-
HCPBGPIE_01744	0.0	-	-	-	S	-	-	-	SEC-C Motif Domain Protein
HCPBGPIE_01745	2.4e-278	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HCPBGPIE_01746	2.2e-160	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HCPBGPIE_01747	1.85e-201	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HCPBGPIE_01748	1.58e-301	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HCPBGPIE_01749	1.16e-41	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HCPBGPIE_01750	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HCPBGPIE_01751	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HCPBGPIE_01752	6.29e-307	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Levansucrase/Invertase
HCPBGPIE_01753	7.24e-204	rssA	-	-	S	-	-	-	Phospholipase, patatin family
HCPBGPIE_01754	1.15e-152	-	-	-	L	-	-	-	Integrase
HCPBGPIE_01755	7.66e-196	-	-	-	EG	-	-	-	EamA-like transporter family
HCPBGPIE_01756	2.82e-299	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HCPBGPIE_01757	9.45e-168	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase
HCPBGPIE_01758	7.3e-131	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase molybdenum cofactor assembly chaperone
HCPBGPIE_01759	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
HCPBGPIE_01760	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HCPBGPIE_01761	1.38e-155	csrR	-	-	K	-	-	-	response regulator
HCPBGPIE_01762	7.21e-39	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HCPBGPIE_01763	1.01e-129	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HCPBGPIE_01764	9.69e-274	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HCPBGPIE_01765	1.1e-179	yqeM	-	-	Q	-	-	-	Methyltransferase
HCPBGPIE_01766	1.9e-79	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HCPBGPIE_01767	3.6e-146	yqeK	-	-	H	-	-	-	Hydrolase, HD family
HCPBGPIE_01768	2.43e-158	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HCPBGPIE_01769	5.4e-63	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
HCPBGPIE_01770	5.44e-279	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
HCPBGPIE_01771	3.7e-123	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
HCPBGPIE_01772	1.1e-125	-	-	-	S	-	-	-	reductase
HCPBGPIE_01773	6.23e-288	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
HCPBGPIE_01774	2.41e-189	-	-	-	E	-	-	-	Glyoxalase-like domain
HCPBGPIE_01775	1.96e-185	-	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HCPBGPIE_01776	1.5e-308	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HCPBGPIE_01777	4.09e-200	hlyD3	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HCPBGPIE_01778	4.85e-167	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HCPBGPIE_01779	7.58e-270	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HCPBGPIE_01781	1.04e-108	-	-	-	-	-	-	-	-
HCPBGPIE_01785	5.56e-119	-	-	-	M	-	-	-	Glycosyl transferase family group 2
HCPBGPIE_01787	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HCPBGPIE_01788	3.69e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
HCPBGPIE_01789	1.38e-37	-	-	-	-	-	-	-	-
HCPBGPIE_01790	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HCPBGPIE_01791	7.43e-129	-	-	-	S	-	-	-	Pfam:DUF3816
HCPBGPIE_01792	1.35e-182	-	-	-	G	-	-	-	MucBP domain
HCPBGPIE_01793	2.26e-145	-	-	-	-	-	-	-	-
HCPBGPIE_01794	7.02e-144	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HCPBGPIE_01795	2.52e-30	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HCPBGPIE_01796	7.18e-86	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
HCPBGPIE_01797	3.81e-62	-	-	-	-	-	-	-	-
HCPBGPIE_01799	3.44e-47	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HCPBGPIE_01800	1.52e-205	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
HCPBGPIE_01801	2.64e-315	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
HCPBGPIE_01802	1.16e-114	XK27_07210	-	-	S	-	-	-	B3 4 domain
HCPBGPIE_01803	8.65e-119	-	-	-	-	-	-	-	-
HCPBGPIE_01804	0.0	arcD	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
HCPBGPIE_01805	0.0	arcT	-	-	E	-	-	-	Dipeptidase
HCPBGPIE_01806	3.66e-274	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
HCPBGPIE_01807	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
HCPBGPIE_01808	3.66e-183	-	-	-	V	-	-	-	Beta-lactamase enzyme family
HCPBGPIE_01809	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HCPBGPIE_01810	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
HCPBGPIE_01811	1.89e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
HCPBGPIE_01812	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HCPBGPIE_01813	5.51e-107	-	-	-	-	-	-	-	-
HCPBGPIE_01814	6.86e-98	-	-	-	O	-	-	-	OsmC-like protein
HCPBGPIE_01815	9.71e-168	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HCPBGPIE_01816	1.08e-39	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HCPBGPIE_01817	6.83e-274	-	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HCPBGPIE_01818	2.49e-43	-	-	-	-	-	-	-	-
HCPBGPIE_01819	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
HCPBGPIE_01820	6.74e-35	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HCPBGPIE_01821	2.05e-156	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
HCPBGPIE_01822	1.66e-303	-	-	-	T	-	-	-	GHKL domain
HCPBGPIE_01823	2.28e-139	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HCPBGPIE_01824	1.2e-91	-	-	-	P	-	-	-	FAD-binding domain
HCPBGPIE_01825	1.16e-72	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
HCPBGPIE_01826	5.61e-87	p75	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
HCPBGPIE_01827	0.0	-	2.4.1.5	GH13	G	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	Glycosyl hydrolase family 70
HCPBGPIE_01828	1.87e-218	-	3.2.1.23, 3.2.1.89	-	G	ko:K01190,ko:K01224	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	arabinogalactan endo-1,4-beta-galactosidase activity
HCPBGPIE_01829	0.0	ganB	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
HCPBGPIE_01830	3.29e-63	-	-	-	S	-	-	-	dextransucrase activity
HCPBGPIE_01831	2.93e-117	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
HCPBGPIE_01832	3.63e-32	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HCPBGPIE_01833	1.63e-97	lysR	-	-	K	-	-	-	Transcriptional regulator
HCPBGPIE_01834	2.67e-111	-	-	-	C	-	-	-	Flavodoxin
HCPBGPIE_01835	1.94e-211	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
HCPBGPIE_01836	2.32e-210	-	-	-	K	-	-	-	COG COG0846 NAD-dependent protein deacetylases, SIR2 family
HCPBGPIE_01837	4.09e-99	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HCPBGPIE_01838	9.82e-106	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HCPBGPIE_01839	9.11e-114	-	-	-	C	-	-	-	Oxidoreductase
HCPBGPIE_01840	3.41e-27	-	-	-	C	-	-	-	Oxidoreductase
HCPBGPIE_01841	2.89e-68	-	-	-	C	-	-	-	Oxidoreductase
HCPBGPIE_01842	3.88e-71	-	-	-	S	-	-	-	macrophage migration inhibitory factor
HCPBGPIE_01843	4.95e-86	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HCPBGPIE_01844	2.09e-115	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HCPBGPIE_01846	1.31e-103	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
HCPBGPIE_01847	2.02e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HCPBGPIE_01848	3.28e-156	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HCPBGPIE_01849	1.98e-263	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HCPBGPIE_01850	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HCPBGPIE_01851	2.64e-87	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NLP P60 protein
HCPBGPIE_01853	5.13e-126	-	-	-	S	-	-	-	enterobacterial common antigen metabolic process
HCPBGPIE_01854	6.08e-235	cps3F	-	-	-	-	-	-	-
HCPBGPIE_01855	4e-109	-	-	-	M	-	-	-	biosynthesis protein
HCPBGPIE_01856	2.08e-145	-	-	-	S	-	-	-	Membrane
HCPBGPIE_01857	1.98e-83	-	-	-	O	-	-	-	Zinc-dependent metalloprotease
HCPBGPIE_01858	2.69e-114	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HCPBGPIE_01859	2.06e-200	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HCPBGPIE_01861	1.97e-53	-	-	-	S	-	-	-	Protein of unknown function (DUF1797)
HCPBGPIE_01862	3.8e-228	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HCPBGPIE_01863	1.09e-250	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HCPBGPIE_01864	3.48e-288	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HCPBGPIE_01865	7.59e-200	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HCPBGPIE_01866	9.78e-228	yueF	-	-	S	-	-	-	AI-2E family transporter
HCPBGPIE_01867	4.64e-46	-	-	-	S	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	dextransucrase activity
HCPBGPIE_01868	5.69e-147	yjbH	-	-	Q	-	-	-	Thioredoxin
HCPBGPIE_01869	7.45e-150	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HCPBGPIE_01870	7.22e-197	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HCPBGPIE_01871	1.13e-220	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HCPBGPIE_01872	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
HCPBGPIE_01873	1.35e-46	-	-	-	C	-	-	-	Heavy-metal-associated domain
HCPBGPIE_01874	5.86e-120	dpsB	-	-	P	-	-	-	Belongs to the Dps family
HCPBGPIE_01875	9.73e-146	fnr	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
HCPBGPIE_01876	2.15e-104	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HCPBGPIE_01878	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HCPBGPIE_01879	3.49e-66	-	-	-	-	-	-	-	-
HCPBGPIE_01880	1.74e-153	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NLP P60 protein
HCPBGPIE_01881	9.93e-40	-	-	-	-	-	-	-	-
HCPBGPIE_01882	4.98e-160	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HCPBGPIE_01883	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HCPBGPIE_01884	1.13e-299	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HCPBGPIE_01886	2.91e-54	-	-	-	M	-	-	-	KxYKxGKxW signal domain protein
HCPBGPIE_01887	8.36e-233	fecB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HCPBGPIE_01888	8.62e-225	-	-	-	-	-	-	-	-
HCPBGPIE_01889	1.1e-95	-	-	-	-	-	-	-	-
HCPBGPIE_01890	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HCPBGPIE_01891	3.95e-127	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HCPBGPIE_01892	7.29e-233	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
HCPBGPIE_01893	6.7e-38	-	-	-	-	-	-	-	-
HCPBGPIE_01894	7.04e-133	-	-	-	K	-	-	-	DNA-templated transcription, initiation
HCPBGPIE_01895	4.81e-50	-	-	-	-	-	-	-	-
HCPBGPIE_01896	0.0	potE	-	-	E	-	-	-	Amino Acid
HCPBGPIE_01897	0.0	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
HCPBGPIE_01898	1.87e-34	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HCPBGPIE_01899	2.59e-135	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HCPBGPIE_01900	7.32e-292	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HCPBGPIE_01901	9.39e-39	-	-	-	-	-	-	-	-
HCPBGPIE_01913	1.31e-161	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
HCPBGPIE_01914	4.08e-16	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
HCPBGPIE_01915	1.41e-102	-	-	-	O	-	-	-	Bacterial dnaA protein
HCPBGPIE_01916	5.39e-64	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
HCPBGPIE_01922	3.23e-45	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)