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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HBCGBFBE_00001	2.6e-135	-	-	-	-	-	-	-	-
HBCGBFBE_00003	2.54e-199	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HBCGBFBE_00004	4.95e-92	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HBCGBFBE_00006	2.13e-74	-	-	-	-	-	-	-	-
HBCGBFBE_00008	1.23e-110	-	-	-	-	-	-	-	-
HBCGBFBE_00009	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HBCGBFBE_00010	2.2e-65	-	-	-	S	-	-	-	Cupredoxin-like domain
HBCGBFBE_00011	1.31e-81	-	-	-	S	-	-	-	Cupredoxin-like domain
HBCGBFBE_00012	7.03e-134	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
HBCGBFBE_00013	3.18e-206	-	-	-	EG	-	-	-	EamA-like transporter family
HBCGBFBE_00014	3.94e-221	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
HBCGBFBE_00015	1.31e-243	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HBCGBFBE_00016	3.05e-198	-	-	-	KT	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	YcbB domain
HBCGBFBE_00017	0.0	xylB	2.7.1.17, 2.7.1.53	-	G	ko:K00854,ko:K00880	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the FGGY kinase family
HBCGBFBE_00018	2.08e-208	xylR	-	-	GK	-	-	-	ROK family
HBCGBFBE_00019	2.49e-39	-	-	-	-	-	-	-	-
HBCGBFBE_00020	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HBCGBFBE_00021	6.42e-140	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
HBCGBFBE_00022	2.71e-200	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HBCGBFBE_00023	0.0	yclK	-	-	T	-	-	-	Histidine kinase
HBCGBFBE_00024	2.7e-172	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
HBCGBFBE_00026	2.2e-110	lytE	-	-	M	-	-	-	Lysin motif
HBCGBFBE_00027	9.84e-194	-	-	-	S	-	-	-	Cof-like hydrolase
HBCGBFBE_00028	4.32e-105	-	-	-	K	-	-	-	Transcriptional regulator
HBCGBFBE_00029	0.0	oatA	-	-	I	-	-	-	Acyltransferase
HBCGBFBE_00030	5.17e-70	-	-	-	-	-	-	-	-
HBCGBFBE_00031	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HBCGBFBE_00032	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HBCGBFBE_00033	7.48e-165	ybbR	-	-	S	-	-	-	YbbR-like protein
HBCGBFBE_00034	6.61e-195	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HBCGBFBE_00035	0.0	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
HBCGBFBE_00036	1.43e-87	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HBCGBFBE_00037	1.31e-213	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HBCGBFBE_00038	2.76e-215	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HBCGBFBE_00039	3.7e-133	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HBCGBFBE_00040	3.55e-99	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
HBCGBFBE_00041	1.46e-112	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HBCGBFBE_00042	6.95e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
HBCGBFBE_00043	1.38e-228	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
HBCGBFBE_00044	1.84e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HBCGBFBE_00045	9.61e-137	-	-	-	-	-	-	-	-
HBCGBFBE_00046	7.73e-109	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HBCGBFBE_00047	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HBCGBFBE_00048	3.43e-189	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
HBCGBFBE_00049	1.43e-47	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HBCGBFBE_00050	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HBCGBFBE_00051	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HBCGBFBE_00052	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HBCGBFBE_00053	2.51e-182	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HBCGBFBE_00054	7.62e-290	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HBCGBFBE_00055	1.31e-243	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HBCGBFBE_00057	4.72e-134	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HBCGBFBE_00058	1.83e-21	-	-	-	-	-	-	-	-
HBCGBFBE_00060	1.94e-218	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HBCGBFBE_00061	5.73e-239	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HBCGBFBE_00062	8.05e-208	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HBCGBFBE_00063	5.51e-316	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HBCGBFBE_00064	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HBCGBFBE_00065	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HBCGBFBE_00066	4.16e-19	-	-	-	-	-	-	-	-
HBCGBFBE_00067	3.57e-150	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
HBCGBFBE_00068	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HBCGBFBE_00069	2.85e-114	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
HBCGBFBE_00070	1.2e-131	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	PFAM extracellular solute-binding protein, family 3
HBCGBFBE_00071	9.18e-51	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	PFAM extracellular solute-binding protein, family 3
HBCGBFBE_00072	1.9e-277	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HBCGBFBE_00073	2.38e-222	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HBCGBFBE_00074	1.43e-208	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
HBCGBFBE_00075	0.0	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
HBCGBFBE_00076	8.36e-174	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
HBCGBFBE_00077	1.79e-214	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HBCGBFBE_00078	5.93e-237	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HBCGBFBE_00079	3.31e-200	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HBCGBFBE_00080	1.38e-226	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HBCGBFBE_00081	1.88e-68	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
HBCGBFBE_00082	2.11e-66	-	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
HBCGBFBE_00083	1.58e-238	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HBCGBFBE_00084	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HBCGBFBE_00085	1.18e-122	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HBCGBFBE_00086	1.73e-148	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
HBCGBFBE_00087	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
HBCGBFBE_00088	6.65e-145	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
HBCGBFBE_00089	2.61e-300	-	-	-	EGP	-	-	-	Major Facilitator
HBCGBFBE_00090	8.81e-89	-	-	-	K	-	-	-	Transcriptional regulator
HBCGBFBE_00091	2.63e-53	-	-	-	-	-	-	-	-
HBCGBFBE_00092	0.0	ydaO	-	-	E	-	-	-	amino acid
HBCGBFBE_00093	0.0	-	-	-	E	-	-	-	amino acid
HBCGBFBE_00094	3.11e-106	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	YbaK proline--tRNA ligase associated domain protein
HBCGBFBE_00095	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HBCGBFBE_00096	1.83e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HBCGBFBE_00098	1.34e-146	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HBCGBFBE_00099	0.0	-	-	-	LV	-	-	-	Eco57I restriction-modification methylase
HBCGBFBE_00100	6.78e-251	-	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
HBCGBFBE_00101	3.59e-64	-	-	-	S	-	-	-	Domain of unknown function (DUF1788)
HBCGBFBE_00102	2.31e-56	-	-	-	S	-	-	-	Putative inner membrane protein (DUF1819)
HBCGBFBE_00103	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HBCGBFBE_00105	7.02e-288	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
HBCGBFBE_00106	5.62e-224	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HBCGBFBE_00107	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HBCGBFBE_00108	1.77e-202	-	-	-	EG	-	-	-	EamA-like transporter family
HBCGBFBE_00109	1.26e-44	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
HBCGBFBE_00110	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HBCGBFBE_00111	2.31e-148	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
HBCGBFBE_00112	9.5e-162	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
HBCGBFBE_00113	1.27e-291	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HBCGBFBE_00114	1.34e-47	-	-	-	S	-	-	-	Transglycosylase associated protein
HBCGBFBE_00115	6.08e-13	-	-	-	S	-	-	-	CsbD-like
HBCGBFBE_00116	3.17e-233	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HBCGBFBE_00117	0.0	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
HBCGBFBE_00118	2.14e-123	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
HBCGBFBE_00119	8.65e-53	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
HBCGBFBE_00120	2.69e-192	-	-	-	-	-	-	-	-
HBCGBFBE_00121	6.02e-34	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
HBCGBFBE_00122	1.27e-108	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HBCGBFBE_00123	2.75e-132	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
HBCGBFBE_00124	3.59e-97	-	-	-	F	-	-	-	Nudix hydrolase
HBCGBFBE_00125	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
HBCGBFBE_00126	1.77e-298	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
HBCGBFBE_00127	1.97e-293	-	-	-	-	-	-	-	-
HBCGBFBE_00128	6.98e-266	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HBCGBFBE_00129	5.39e-184	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HBCGBFBE_00130	2.49e-187	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HBCGBFBE_00131	1.25e-262	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HBCGBFBE_00132	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HBCGBFBE_00133	8.65e-226	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HBCGBFBE_00134	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HBCGBFBE_00135	4.16e-112	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HBCGBFBE_00136	0.0	yagE	-	-	E	-	-	-	amino acid
HBCGBFBE_00137	9.45e-152	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
HBCGBFBE_00138	1.73e-75	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HBCGBFBE_00139	1.33e-162	-	-	-	L	-	-	-	Helix-turn-helix domain
HBCGBFBE_00140	1.67e-192	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HBCGBFBE_00141	3.42e-233	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HBCGBFBE_00142	5.46e-233	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
HBCGBFBE_00143	7.72e-178	-	-	-	IQ	-	-	-	KR domain
HBCGBFBE_00144	1.47e-171	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HBCGBFBE_00145	8.59e-127	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HBCGBFBE_00146	4.68e-314	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HBCGBFBE_00147	4.83e-146	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HBCGBFBE_00148	6.5e-71	-	-	-	-	-	-	-	-
HBCGBFBE_00149	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HBCGBFBE_00150	6.35e-69	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
HBCGBFBE_00151	2.53e-241	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HBCGBFBE_00152	1.3e-95	-	-	-	K	-	-	-	Transcriptional regulator
HBCGBFBE_00153	3.46e-207	-	-	-	-	-	-	-	-
HBCGBFBE_00154	1.62e-229	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HBCGBFBE_00155	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
HBCGBFBE_00156	1.37e-270	-	-	-	EGP	-	-	-	Major Facilitator
HBCGBFBE_00157	3.18e-11	-	-	-	-	-	-	-	-
HBCGBFBE_00158	1.78e-83	-	-	-	-	-	-	-	-
HBCGBFBE_00159	1.17e-247	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HBCGBFBE_00160	7.46e-106	uspA3	-	-	T	-	-	-	universal stress protein
HBCGBFBE_00161	0.0	fusA1	-	-	J	-	-	-	elongation factor G
HBCGBFBE_00162	2.17e-213	-	-	-	GK	-	-	-	ROK family
HBCGBFBE_00163	9.75e-311	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HBCGBFBE_00164	4.49e-180	yfhR3	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
HBCGBFBE_00165	1.05e-310	-	-	-	E	-	-	-	amino acid
HBCGBFBE_00166	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HBCGBFBE_00167	3.02e-171	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
HBCGBFBE_00168	9.16e-111	ebsC	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HBCGBFBE_00169	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HBCGBFBE_00170	0.0	rtpR	1.17.4.2	-	F	ko:K00527	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	ribonucleoside-triphosphate reductase activity
HBCGBFBE_00171	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HBCGBFBE_00172	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HBCGBFBE_00173	1.64e-23	-	-	-	K	-	-	-	Winged helix-turn-helix DNA-binding
HBCGBFBE_00174	1.86e-227	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HBCGBFBE_00175	3.85e-24	-	-	-	S	-	-	-	PFAM Archaeal ATPase
HBCGBFBE_00176	4.06e-103	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
HBCGBFBE_00177	4.28e-66	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
HBCGBFBE_00178	2.34e-92	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
HBCGBFBE_00179	8.25e-31	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HBCGBFBE_00180	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HBCGBFBE_00181	6.06e-168	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HBCGBFBE_00182	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HBCGBFBE_00183	2.09e-211	-	-	-	G	-	-	-	Phosphotransferase enzyme family
HBCGBFBE_00184	1.88e-101	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HBCGBFBE_00185	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HBCGBFBE_00186	4.8e-72	-	-	-	-	-	-	-	-
HBCGBFBE_00187	6.78e-165	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HBCGBFBE_00188	2.69e-228	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
HBCGBFBE_00189	7.92e-76	-	-	-	-	-	-	-	-
HBCGBFBE_00191	4.78e-222	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HBCGBFBE_00193	1.01e-254	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
HBCGBFBE_00194	0.0	pepD3	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HBCGBFBE_00195	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HBCGBFBE_00196	3.81e-274	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HBCGBFBE_00197	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HBCGBFBE_00198	5.24e-114	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HBCGBFBE_00199	1.13e-247	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HBCGBFBE_00200	1.79e-84	-	-	-	-	-	-	-	-
HBCGBFBE_00201	8.98e-225	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HBCGBFBE_00202	1.21e-215	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HBCGBFBE_00203	1.38e-77	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HBCGBFBE_00204	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HBCGBFBE_00205	1.96e-65	ylxQ	-	-	J	-	-	-	ribosomal protein
HBCGBFBE_00206	5.93e-60	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
HBCGBFBE_00207	1.68e-274	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HBCGBFBE_00208	1.1e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HBCGBFBE_00209	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HBCGBFBE_00210	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HBCGBFBE_00211	5.46e-297	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HBCGBFBE_00212	1.18e-177	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HBCGBFBE_00213	1.83e-182	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HBCGBFBE_00214	4.23e-123	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HBCGBFBE_00215	2.21e-167	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HBCGBFBE_00216	3.14e-197	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HBCGBFBE_00217	3.54e-184	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HBCGBFBE_00218	1.02e-233	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HBCGBFBE_00219	6.79e-65	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
HBCGBFBE_00220	5.9e-182	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
HBCGBFBE_00221	7.51e-152	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
HBCGBFBE_00222	1.6e-40	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
HBCGBFBE_00223	2.7e-47	ynzC	-	-	S	-	-	-	UPF0291 protein
HBCGBFBE_00224	4.18e-147	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HBCGBFBE_00225	2.88e-270	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
HBCGBFBE_00226	7.77e-159	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HBCGBFBE_00228	1.03e-120	-	-	-	-	-	-	-	-
HBCGBFBE_00229	3.44e-117	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HBCGBFBE_00230	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HBCGBFBE_00231	3.87e-200	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
HBCGBFBE_00232	3.39e-226	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HBCGBFBE_00233	3.8e-316	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HBCGBFBE_00234	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HBCGBFBE_00235	2.44e-20	-	-	-	-	-	-	-	-
HBCGBFBE_00236	1.11e-78	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
HBCGBFBE_00237	2.01e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HBCGBFBE_00238	2.06e-297	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HBCGBFBE_00239	5.54e-303	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HBCGBFBE_00240	4.94e-288	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HBCGBFBE_00241	3.58e-208	-	-	-	S	-	-	-	Tetratricopeptide repeat
HBCGBFBE_00242	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HBCGBFBE_00243	1.74e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HBCGBFBE_00244	1.44e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HBCGBFBE_00245	9.21e-200	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HBCGBFBE_00246	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HBCGBFBE_00247	7.1e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
HBCGBFBE_00248	3.4e-138	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
HBCGBFBE_00249	1.23e-251	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HBCGBFBE_00250	3.05e-116	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HBCGBFBE_00251	6.8e-129	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
HBCGBFBE_00252	6.37e-60	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
HBCGBFBE_00253	7.54e-284	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HBCGBFBE_00254	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HBCGBFBE_00255	3.52e-177	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
HBCGBFBE_00256	7.04e-63	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
HBCGBFBE_00257	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
HBCGBFBE_00258	2.13e-311	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HBCGBFBE_00259	9.42e-232	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
HBCGBFBE_00260	2.44e-267	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
HBCGBFBE_00261	1.38e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HBCGBFBE_00262	6.08e-102	-	-	-	-	-	-	-	-
HBCGBFBE_00263	9.99e-44	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HBCGBFBE_00264	1.69e-229	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic
HBCGBFBE_00265	4.37e-39	-	-	-	-	-	-	-	-
HBCGBFBE_00266	5.19e-262	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
HBCGBFBE_00268	5.28e-76	-	-	-	-	-	-	-	-
HBCGBFBE_00269	7.55e-265	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HBCGBFBE_00270	3.11e-268	yojA	-	-	EG	ko:K03299	-	ko00000,ko02000	GntP family permease
HBCGBFBE_00271	2.41e-280	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
HBCGBFBE_00272	1.41e-53	-	1.3.5.4	-	S	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FMN binding
HBCGBFBE_00273	5.71e-152	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HBCGBFBE_00274	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
HBCGBFBE_00275	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HBCGBFBE_00277	3.16e-260	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HBCGBFBE_00278	0.0	-	-	-	L	-	-	-	DNA helicase
HBCGBFBE_00279	7.04e-107	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
HBCGBFBE_00280	5.96e-241	-	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
HBCGBFBE_00281	5.54e-243	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HBCGBFBE_00282	2.53e-214	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HBCGBFBE_00283	2.08e-283	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
HBCGBFBE_00284	1.09e-227	-	-	-	-	-	-	-	-
HBCGBFBE_00285	5.9e-168	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
HBCGBFBE_00287	4.74e-208	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
HBCGBFBE_00288	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HBCGBFBE_00289	5.3e-200	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
HBCGBFBE_00290	6.03e-128	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HBCGBFBE_00291	9.83e-204	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HBCGBFBE_00292	2.74e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
HBCGBFBE_00293	5.5e-203	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HBCGBFBE_00294	1.66e-214	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HBCGBFBE_00295	2.31e-156	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HBCGBFBE_00296	1.68e-163	-	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
HBCGBFBE_00297	5.24e-191	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HBCGBFBE_00298	3.17e-314	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HBCGBFBE_00299	3.53e-229	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HBCGBFBE_00300	1.6e-100	-	-	-	-	-	-	-	-
HBCGBFBE_00301	7.71e-189	yidA	-	-	S	-	-	-	hydrolase
HBCGBFBE_00302	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
HBCGBFBE_00303	4.82e-188	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
HBCGBFBE_00304	9.28e-89	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
HBCGBFBE_00305	1.14e-81	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HBCGBFBE_00306	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HBCGBFBE_00307	5.29e-300	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HBCGBFBE_00308	9.43e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HBCGBFBE_00309	1.78e-300	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HBCGBFBE_00310	1.86e-212	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HBCGBFBE_00311	4.29e-162	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
HBCGBFBE_00312	3.74e-290	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HBCGBFBE_00313	6.08e-179	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HBCGBFBE_00314	6.21e-207	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
HBCGBFBE_00315	1.51e-154	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
HBCGBFBE_00316	2.71e-112	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HBCGBFBE_00317	4.93e-123	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HBCGBFBE_00318	1.06e-203	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HBCGBFBE_00319	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HBCGBFBE_00320	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HBCGBFBE_00321	8.02e-159	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
HBCGBFBE_00322	1.11e-234	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
HBCGBFBE_00323	4.83e-212	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HBCGBFBE_00324	0.0	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HBCGBFBE_00325	1e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HBCGBFBE_00326	1.23e-297	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
HBCGBFBE_00327	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HBCGBFBE_00328	2.63e-08	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
HBCGBFBE_00329	1.88e-80	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HBCGBFBE_00330	1.54e-269	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HBCGBFBE_00331	1.3e-82	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HBCGBFBE_00332	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
HBCGBFBE_00333	2.75e-309	codA	3.5.4.1	-	F	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	cytosine deaminase
HBCGBFBE_00334	2.06e-188	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
HBCGBFBE_00335	2.7e-145	-	-	-	S	-	-	-	(CBS) domain
HBCGBFBE_00336	7.98e-132	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HBCGBFBE_00337	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HBCGBFBE_00338	1.18e-51	yabO	-	-	J	-	-	-	S4 domain protein
HBCGBFBE_00339	7.15e-75	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HBCGBFBE_00340	1.65e-102	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
HBCGBFBE_00341	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HBCGBFBE_00342	3.68e-125	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HBCGBFBE_00343	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HBCGBFBE_00344	7.93e-219	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HBCGBFBE_00345	1.53e-241	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HBCGBFBE_00346	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HBCGBFBE_00349	9.75e-26	-	-	-	-	-	-	-	-
HBCGBFBE_00350	7.27e-178	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
HBCGBFBE_00351	9.01e-90	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
HBCGBFBE_00352	0.0	-	-	-	S	-	-	-	membrane
HBCGBFBE_00353	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HBCGBFBE_00354	1.53e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HBCGBFBE_00355	9.34e-130	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HBCGBFBE_00356	1.43e-16	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
HBCGBFBE_00357	1.38e-59	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
HBCGBFBE_00358	7.07e-48	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
HBCGBFBE_00359	1.02e-234	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
HBCGBFBE_00360	7.66e-88	yqhL	-	-	P	-	-	-	Rhodanese-like protein
HBCGBFBE_00361	1.18e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF3042)
HBCGBFBE_00362	7.13e-227	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HBCGBFBE_00363	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HBCGBFBE_00364	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HBCGBFBE_00365	8.1e-281	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HBCGBFBE_00366	1.28e-18	-	-	-	-	-	-	-	-
HBCGBFBE_00367	1.14e-195	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HBCGBFBE_00368	1.99e-131	msrA	1.8.4.11	-	C	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HBCGBFBE_00369	3.63e-66	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HBCGBFBE_00370	4.87e-203	-	-	-	-	-	-	-	-
HBCGBFBE_00371	1.47e-223	-	-	-	-	-	-	-	-
HBCGBFBE_00372	4.21e-116	-	-	-	S	-	-	-	Protein conserved in bacteria
HBCGBFBE_00376	1.34e-144	-	-	-	K	-	-	-	Transcriptional regulator
HBCGBFBE_00377	2.68e-67	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HBCGBFBE_00378	1.77e-72	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
HBCGBFBE_00379	5.07e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HBCGBFBE_00380	3.84e-170	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HBCGBFBE_00381	1.06e-256	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HBCGBFBE_00382	1e-146	-	-	-	J	-	-	-	2'-5' RNA ligase superfamily
HBCGBFBE_00383	2.27e-93	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
HBCGBFBE_00384	2.24e-92	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HBCGBFBE_00385	1.61e-192	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HBCGBFBE_00386	1.09e-309	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HBCGBFBE_00387	4.02e-58	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HBCGBFBE_00388	6.95e-205	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HBCGBFBE_00389	4.85e-192	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HBCGBFBE_00390	3.2e-100	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HBCGBFBE_00391	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HBCGBFBE_00392	9e-72	-	-	-	-	-	-	-	-
HBCGBFBE_00393	4.37e-148	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HBCGBFBE_00394	6.66e-43	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HBCGBFBE_00395	2.2e-273	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HBCGBFBE_00396	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HBCGBFBE_00397	8.26e-222	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HBCGBFBE_00398	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HBCGBFBE_00399	2.47e-167	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HBCGBFBE_00400	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HBCGBFBE_00401	3.75e-212	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HBCGBFBE_00402	5.46e-152	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HBCGBFBE_00403	1.91e-156	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HBCGBFBE_00404	1.1e-34	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HBCGBFBE_00405	1.05e-77	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HBCGBFBE_00406	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
HBCGBFBE_00407	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HBCGBFBE_00408	4.72e-241	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HBCGBFBE_00409	1.81e-50	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HBCGBFBE_00410	1.57e-168	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HBCGBFBE_00411	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HBCGBFBE_00412	2.01e-284	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HBCGBFBE_00413	4.23e-76	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HBCGBFBE_00414	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HBCGBFBE_00415	1.21e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HBCGBFBE_00416	2.54e-51	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HBCGBFBE_00417	5.33e-119	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HBCGBFBE_00418	5.46e-183	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HBCGBFBE_00419	0.0	-	-	-	E	ko:K03294	-	ko00000	amino acid
HBCGBFBE_00420	3.03e-83	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HBCGBFBE_00421	3.67e-46	-	-	-	-	-	-	-	-
HBCGBFBE_00422	9e-72	-	-	-	S	-	-	-	Mazg nucleotide pyrophosphohydrolase
HBCGBFBE_00423	8.83e-205	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HBCGBFBE_00424	1.55e-109	-	-	-	-	-	-	-	-
HBCGBFBE_00425	3.2e-185	cobT	2.4.2.21	-	F	ko:K00768	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
HBCGBFBE_00426	4.44e-91	-	-	-	H	-	-	-	Uroporphyrinogen-III synthase
HBCGBFBE_00427	4.47e-95	cobC	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphoglycerate mutase family
HBCGBFBE_00428	2.56e-152	cobS	2.7.8.26	-	H	ko:K02233	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HBCGBFBE_00429	1.41e-98	cobU	2.7.1.156, 2.7.7.62	-	H	ko:K02231	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Cobinamide kinase / cobinamide phosphate guanyltransferase
HBCGBFBE_00430	3.91e-305	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
HBCGBFBE_00431	2.77e-223	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Delta-aminolevulinic acid dehydratase
HBCGBFBE_00432	1.32e-173	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HBCGBFBE_00433	6.66e-246	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HBCGBFBE_00434	3.85e-75	cysG	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Putative NAD(P)-binding
HBCGBFBE_00435	2.78e-302	cobQ	6.3.5.10	-	H	ko:K02232	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
HBCGBFBE_00436	7.19e-155	cbiO	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	part of an ABC transporter complex. Responsible for energy coupling to the transport system
HBCGBFBE_00437	1.88e-131	cbiQ	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HBCGBFBE_00438	8.36e-59	cbiN	-	-	P	ko:K02009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
HBCGBFBE_00439	6.68e-159	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
HBCGBFBE_00440	5.52e-117	cbiL	2.1.1.130, 2.1.1.151	-	H	ko:K03394	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
HBCGBFBE_00441	3.42e-139	cbiK	4.99.1.3	-	H	ko:K02190	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Cobalt chelatase (CbiK)
HBCGBFBE_00442	1.32e-220	cobA	2.1.1.107, 4.2.1.75	-	H	ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
HBCGBFBE_00443	1.43e-123	cobK	1.3.1.106, 1.3.1.54	-	H	ko:K05895	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Precorrin-6x reductase CbiJ/CobK
HBCGBFBE_00444	7.98e-166	cbiH	2.1.1.131	-	H	ko:K05934	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
HBCGBFBE_00445	1.34e-182	cbiG	3.7.1.12	-	H	ko:K02189	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Cobalamin synthesis G C-terminus
HBCGBFBE_00446	8.16e-165	cbiF	2.1.1.133, 2.1.1.271	-	H	ko:K05936	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
HBCGBFBE_00447	1.72e-90	cbiT	2.1.1.196	-	H	ko:K02191	ko00860,map00860	ko00000,ko00001,ko01000	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
HBCGBFBE_00448	6.65e-101	cbiE	2.1.1.289	-	H	ko:K03399	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
HBCGBFBE_00449	1.2e-245	cbiD	2.1.1.195	-	H	ko:K02188	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
HBCGBFBE_00450	3.17e-138	cbiC	5.4.99.60, 5.4.99.61	-	H	ko:K06042	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Precorrin-8X methylmutase
HBCGBFBE_00451	3.57e-185	cobD	6.3.1.10	-	H	ko:K02227	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HBCGBFBE_00452	2.45e-260	cbiA	6.3.5.11, 6.3.5.9	-	F	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
HBCGBFBE_00453	4.9e-216	cobD	4.1.1.81	-	E	ko:K04720	ko00860,map00860	ko00000,ko00001,ko01000	Aminotransferase class I and II
HBCGBFBE_00454	1.72e-102	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Cobalamin adenosyltransferase
HBCGBFBE_00455	2e-146	nqo1	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
HBCGBFBE_00456	4.54e-95	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HBCGBFBE_00457	1.18e-89	eutP	-	-	E	ko:K04029	-	ko00000	Ethanolamine utilisation - propanediol utilisation
HBCGBFBE_00458	3.45e-87	-	-	-	P	-	-	-	Cadmium resistance transporter
HBCGBFBE_00459	1.06e-96	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
HBCGBFBE_00460	7.99e-150	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Pfam:Y_phosphatase3C
HBCGBFBE_00461	9.15e-72	-	-	-	E	ko:K04031	-	ko00000	BMC
HBCGBFBE_00462	2.5e-278	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HBCGBFBE_00463	4.33e-259	pduQ	-	-	C	ko:K13921	ko00640,map00640	ko00000,ko00001	Iron-containing alcohol dehydrogenase
HBCGBFBE_00464	0.0	pduP	1.2.1.87	-	C	ko:K13922	ko00640,map00640	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
HBCGBFBE_00465	1.14e-101	pduO	-	-	S	-	-	-	Haem-degrading
HBCGBFBE_00466	2.85e-134	-	-	-	S	-	-	-	Cobalamin adenosyltransferase
HBCGBFBE_00467	5.63e-55	pduN	-	-	CQ	ko:K04028	-	ko00000	Ethanolamine utilisation protein EutN/carboxysome
HBCGBFBE_00468	1.25e-103	-	-	-	S	-	-	-	Putative propanediol utilisation
HBCGBFBE_00469	1.98e-148	pduL	2.3.1.222	-	Q	ko:K13923	ko00640,map00640	ko00000,ko00001,ko01000	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
HBCGBFBE_00470	3.65e-53	pduA_2	-	-	CQ	ko:K04027	-	ko00000	BMC
HBCGBFBE_00471	4.63e-75	-	-	-	CQ	-	-	-	BMC
HBCGBFBE_00472	5.18e-59	pduH	-	-	S	-	-	-	Dehydratase medium subunit
HBCGBFBE_00473	0.0	pduG	-	-	D	-	-	-	Diol dehydratase reactivase ATPase-like domain
HBCGBFBE_00474	3.09e-97	pduE	4.2.1.28	-	Q	ko:K13920	ko00640,map00640	ko00000,ko00001,ko01000	Dehydratase small subunit
HBCGBFBE_00475	5e-162	pduD	4.2.1.28	-	Q	ko:K13919	ko00640,map00640	ko00000,ko00001,ko01000	Dehydratase medium subunit
HBCGBFBE_00476	0.0	pduC	4.2.1.28	-	Q	ko:K01699	ko00640,map00640	ko00000,ko00001,ko01000	Dehydratase large subunit
HBCGBFBE_00477	3.41e-170	pduB	-	-	E	-	-	-	BMC
HBCGBFBE_00478	2.33e-50	-	-	-	CQ	-	-	-	BMC
HBCGBFBE_00479	1.69e-202	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HBCGBFBE_00480	4.02e-177	eutJ	-	-	E	ko:K04024	-	ko00000	Hsp70 protein
HBCGBFBE_00481	2.7e-170	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HBCGBFBE_00482	4.54e-119	-	-	-	-	-	-	-	-
HBCGBFBE_00483	8.33e-161	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HBCGBFBE_00484	8.61e-214	XK27_12525	-	-	S	-	-	-	AI-2E family transporter
HBCGBFBE_00485	2.9e-168	XK27_07210	-	-	S	-	-	-	B3 4 domain
HBCGBFBE_00486	8.16e-103	yybA	-	-	K	-	-	-	Transcriptional regulator
HBCGBFBE_00487	5.25e-118	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HBCGBFBE_00488	3.16e-114	-	-	-	GM	-	-	-	epimerase
HBCGBFBE_00489	1.39e-198	-	-	-	V	-	-	-	(ABC) transporter
HBCGBFBE_00490	2.37e-307	yhdP	-	-	S	-	-	-	Transporter associated domain
HBCGBFBE_00491	1.98e-110	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
HBCGBFBE_00492	3.68e-97	-	-	-	S	ko:K04750	-	ko00000	3-demethylubiquinone-9 3-methyltransferase
HBCGBFBE_00493	2.64e-246	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
HBCGBFBE_00494	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HBCGBFBE_00495	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HBCGBFBE_00496	1.06e-53	-	-	-	-	-	-	-	-
HBCGBFBE_00497	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HBCGBFBE_00504	1.74e-125	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HBCGBFBE_00505	1.63e-312	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
HBCGBFBE_00506	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
HBCGBFBE_00507	3.94e-144	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HBCGBFBE_00508	3.48e-192	-	-	-	O	-	-	-	Uncharacterized protein family (UPF0051)
HBCGBFBE_00509	1.15e-138	-	-	-	M	-	-	-	LysM domain protein
HBCGBFBE_00510	0.0	-	-	-	EP	-	-	-	Psort location Cytoplasmic, score
HBCGBFBE_00511	4.57e-137	-	-	-	M	-	-	-	LysM domain protein
HBCGBFBE_00512	1.29e-196	yeaE	-	-	S	-	-	-	Aldo keto
HBCGBFBE_00513	4.63e-101	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HBCGBFBE_00514	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
HBCGBFBE_00515	1.08e-101	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HBCGBFBE_00516	5.03e-111	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HBCGBFBE_00517	7.03e-33	-	-	-	-	-	-	-	-
HBCGBFBE_00518	8.28e-135	-	-	-	V	-	-	-	VanZ like family
HBCGBFBE_00519	1.72e-303	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HBCGBFBE_00520	1.25e-111	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HBCGBFBE_00521	0.0	-	-	-	EGP	-	-	-	Major Facilitator
HBCGBFBE_00522	4.29e-119	tag1	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HBCGBFBE_00523	2.71e-280	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HBCGBFBE_00524	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HBCGBFBE_00525	2.42e-54	-	-	-	-	-	-	-	-
HBCGBFBE_00526	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HBCGBFBE_00527	1.61e-192	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HBCGBFBE_00528	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
HBCGBFBE_00529	1.08e-112	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HBCGBFBE_00530	9.09e-224	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HBCGBFBE_00531	3.06e-150	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HBCGBFBE_00532	3.08e-146	-	-	-	-	-	-	-	-
HBCGBFBE_00533	8.42e-237	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
HBCGBFBE_00534	1.63e-207	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HBCGBFBE_00535	1.52e-43	-	-	-	-	-	-	-	-
HBCGBFBE_00536	4.68e-145	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HBCGBFBE_00537	2.17e-57	-	-	-	-	-	-	-	-
HBCGBFBE_00539	6.82e-72	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HBCGBFBE_00540	4.71e-114	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HBCGBFBE_00541	3.36e-136	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
HBCGBFBE_00542	8.17e-285	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HBCGBFBE_00543	2.97e-136	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
HBCGBFBE_00544	4.65e-277	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
HBCGBFBE_00545	9.3e-61	-	-	-	-	-	-	-	-
HBCGBFBE_00546	1.49e-54	-	-	-	-	-	-	-	-
HBCGBFBE_00548	3.88e-213	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HBCGBFBE_00549	2.15e-194	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HBCGBFBE_00550	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HBCGBFBE_00551	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HBCGBFBE_00552	3.75e-77	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HBCGBFBE_00553	2.62e-282	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
HBCGBFBE_00554	0.0	yhaN	-	-	L	-	-	-	AAA domain
HBCGBFBE_00555	3.96e-178	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HBCGBFBE_00557	4.99e-101	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
HBCGBFBE_00558	2.7e-175	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HBCGBFBE_00559	6.64e-279	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HBCGBFBE_00560	1.85e-157	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HBCGBFBE_00561	6.82e-74	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HBCGBFBE_00562	1.17e-135	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HBCGBFBE_00563	7.01e-153	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HBCGBFBE_00564	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
HBCGBFBE_00565	5.69e-207	-	-	-	EG	-	-	-	EamA-like transporter family
HBCGBFBE_00566	1.75e-161	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
HBCGBFBE_00567	9.09e-113	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
HBCGBFBE_00568	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HBCGBFBE_00569	2.1e-219	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
HBCGBFBE_00570	1.71e-217	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
HBCGBFBE_00571	4.11e-274	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
HBCGBFBE_00572	8.91e-248	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HBCGBFBE_00573	5.52e-119	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
HBCGBFBE_00574	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HBCGBFBE_00575	2.43e-241	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein-like domain
HBCGBFBE_00576	6.76e-213	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HBCGBFBE_00577	3.4e-229	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HBCGBFBE_00578	4.38e-161	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
HBCGBFBE_00579	3.69e-87	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
HBCGBFBE_00580	8.31e-169	lytT	-	-	K	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator receiver
HBCGBFBE_00581	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	LytS YhcK-type transmembrane receptor domain protein
HBCGBFBE_00582	1.54e-191	-	-	-	O	-	-	-	Band 7 protein
HBCGBFBE_00583	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
HBCGBFBE_00584	1.3e-200	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HBCGBFBE_00585	2.38e-50	-	-	-	S	-	-	-	Cytochrome B5
HBCGBFBE_00586	5.87e-147	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
HBCGBFBE_00587	3.86e-205	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HBCGBFBE_00588	1.18e-76	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HBCGBFBE_00589	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
HBCGBFBE_00590	2.61e-105	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
HBCGBFBE_00591	1.76e-296	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HBCGBFBE_00592	6.47e-303	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
HBCGBFBE_00593	1.82e-183	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
HBCGBFBE_00594	2.32e-43	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
HBCGBFBE_00595	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HBCGBFBE_00596	5.19e-27	-	-	-	-	-	-	-	-
HBCGBFBE_00597	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HBCGBFBE_00598	6.96e-201	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HBCGBFBE_00599	9.54e-85	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
HBCGBFBE_00600	3.51e-142	yvrI	-	-	K	ko:K03091,ko:K03093	-	ko00000,ko03021	sigma factor activity
HBCGBFBE_00601	3.07e-265	-	-	-	G	-	-	-	Transporter, major facilitator family protein
HBCGBFBE_00602	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HBCGBFBE_00603	7.07e-144	-	-	-	T	ko:K10716	-	ko00000,ko02000	Ion transport 2 domain protein
HBCGBFBE_00604	2.72e-102	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HBCGBFBE_00605	3.74e-286	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HBCGBFBE_00606	9.71e-124	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
HBCGBFBE_00607	5.59e-249	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HBCGBFBE_00608	1.1e-229	rihA	-	-	F	ko:K01250	-	ko00000,ko01000	Inosine-uridine preferring nucleoside hydrolase
HBCGBFBE_00609	7.67e-252	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HBCGBFBE_00610	1.13e-289	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HBCGBFBE_00611	1.16e-133	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HBCGBFBE_00612	2.06e-197	-	-	-	S	-	-	-	Helix-turn-helix domain
HBCGBFBE_00613	0.0	ymfH	-	-	S	-	-	-	Peptidase M16
HBCGBFBE_00614	2.13e-294	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
HBCGBFBE_00615	4.04e-205	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HBCGBFBE_00616	2.06e-151	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HBCGBFBE_00617	4.45e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HBCGBFBE_00618	1.62e-118	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
HBCGBFBE_00619	4.46e-194	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HBCGBFBE_00620	8.33e-230	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
HBCGBFBE_00621	6.98e-156	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
HBCGBFBE_00622	5.23e-313	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HBCGBFBE_00623	1.22e-292	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HBCGBFBE_00624	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HBCGBFBE_00625	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HBCGBFBE_00626	9.83e-236	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
HBCGBFBE_00627	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
HBCGBFBE_00628	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HBCGBFBE_00629	5.83e-292	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HBCGBFBE_00630	2.48e-274	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HBCGBFBE_00631	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HBCGBFBE_00632	5.96e-139	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HBCGBFBE_00633	0.0	-	-	-	L	-	-	-	Transposase
HBCGBFBE_00634	1.13e-300	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HBCGBFBE_00635	0.0	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HBCGBFBE_00636	0.0	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HBCGBFBE_00637	8.18e-174	-	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
HBCGBFBE_00638	2.41e-179	-	-	-	S	-	-	-	Membrane
HBCGBFBE_00639	2e-98	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase
HBCGBFBE_00640	9.79e-29	-	-	-	-	-	-	-	-
HBCGBFBE_00641	2.03e-111	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HBCGBFBE_00642	1.88e-309	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HBCGBFBE_00643	3.61e-61	-	-	-	-	-	-	-	-
HBCGBFBE_00644	1.95e-109	uspA	-	-	T	-	-	-	universal stress protein
HBCGBFBE_00645	8.8e-264	araR	-	-	K	ko:K02103	-	ko00000,ko03000	Transcriptional regulator
HBCGBFBE_00646	3.44e-200	yvgN	-	-	S	-	-	-	Aldo keto reductase
HBCGBFBE_00647	3.47e-123	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
HBCGBFBE_00648	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
HBCGBFBE_00649	1.91e-178	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HBCGBFBE_00650	0.0	araB	2.7.1.16	-	G	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	carbohydrate kinase FGGY
HBCGBFBE_00651	0.0	araP	-	-	U	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HBCGBFBE_00652	9.73e-143	qacA	-	-	EGP	-	-	-	Major Facilitator
HBCGBFBE_00653	1.93e-241	-	-	-	I	-	-	-	Alpha beta
HBCGBFBE_00654	5.59e-134	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
HBCGBFBE_00655	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HBCGBFBE_00657	2.24e-205	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HBCGBFBE_00658	1.91e-153	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HBCGBFBE_00659	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HBCGBFBE_00660	1.26e-96	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HBCGBFBE_00661	9.15e-72	-	-	-	-	-	-	-	-
HBCGBFBE_00662	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HBCGBFBE_00663	8.69e-277	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HBCGBFBE_00664	2.11e-140	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HBCGBFBE_00665	1.06e-142	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HBCGBFBE_00666	3.85e-195	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HBCGBFBE_00667	1.14e-172	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HBCGBFBE_00668	4.83e-108	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HBCGBFBE_00669	2.34e-142	-	-	-	S	-	-	-	VIT family
HBCGBFBE_00670	7.33e-152	-	-	-	S	-	-	-	membrane
HBCGBFBE_00671	1.65e-211	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
HBCGBFBE_00672	9.44e-161	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
HBCGBFBE_00673	2.17e-43	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HBCGBFBE_00674	2.98e-166	-	-	-	S	-	-	-	Putative threonine/serine exporter
HBCGBFBE_00675	5.02e-105	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HBCGBFBE_00676	2.79e-153	-	-	-	I	-	-	-	phosphatase
HBCGBFBE_00678	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
HBCGBFBE_00679	7.78e-150	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HBCGBFBE_00685	1.77e-168	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
HBCGBFBE_00686	4.62e-21	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
HBCGBFBE_00687	8.94e-250	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HBCGBFBE_00688	1.39e-101	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
HBCGBFBE_00689	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HBCGBFBE_00690	2.09e-143	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HBCGBFBE_00691	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HBCGBFBE_00692	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HBCGBFBE_00693	1.15e-263	-	-	-	-	-	-	-	-
HBCGBFBE_00694	1.97e-153	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
HBCGBFBE_00695	2.51e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HBCGBFBE_00696	2.06e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HBCGBFBE_00697	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HBCGBFBE_00698	5.18e-222	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
HBCGBFBE_00699	4e-110	-	-	-	F	-	-	-	NUDIX domain
HBCGBFBE_00700	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HBCGBFBE_00701	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HBCGBFBE_00702	1.9e-139	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HBCGBFBE_00703	7.89e-212	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HBCGBFBE_00704	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HBCGBFBE_00705	7.84e-207	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
HBCGBFBE_00706	2.05e-180	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HBCGBFBE_00707	1.99e-204	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HBCGBFBE_00708	1.33e-47	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HBCGBFBE_00709	5.75e-141	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
HBCGBFBE_00710	4.79e-221	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HBCGBFBE_00711	6.38e-196	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
HBCGBFBE_00712	2.59e-144	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
HBCGBFBE_00713	3.38e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HBCGBFBE_00714	3.61e-247	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HBCGBFBE_00715	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HBCGBFBE_00716	4.94e-287	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HBCGBFBE_00717	9.5e-301	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
HBCGBFBE_00718	1.6e-54	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HBCGBFBE_00719	0.0	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HBCGBFBE_00720	1e-272	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HBCGBFBE_00721	1.55e-152	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HBCGBFBE_00722	2.15e-83	-	-	-	M	-	-	-	Lysin motif
HBCGBFBE_00723	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HBCGBFBE_00724	7.6e-246	-	-	-	S	-	-	-	Helix-turn-helix domain
HBCGBFBE_00725	2.65e-133	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HBCGBFBE_00726	1.67e-163	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HBCGBFBE_00727	1.35e-135	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HBCGBFBE_00728	1.95e-177	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HBCGBFBE_00729	3.67e-86	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HBCGBFBE_00730	2.35e-211	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
HBCGBFBE_00731	1.08e-214	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
HBCGBFBE_00732	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HBCGBFBE_00733	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HBCGBFBE_00734	1.11e-41	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HBCGBFBE_00735	2.61e-300	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HBCGBFBE_00736	1.85e-201	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HBCGBFBE_00737	2.2e-160	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HBCGBFBE_00738	1.69e-278	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HBCGBFBE_00739	1.81e-36	-	-	-	S	-	-	-	YSIRK type signal peptide
HBCGBFBE_00740	3.08e-88	-	2.1.1.72, 3.1.21.3	AA10,CBM73	M	ko:K01154,ko:K02014,ko:K03933,ko:K07316	-	ko00000,ko01000,ko02000,ko02048	domain protein
HBCGBFBE_00741	5.85e-289	-	2.1.1.72, 3.1.21.3	AA10,CBM73	M	ko:K01154,ko:K02014,ko:K03933,ko:K07316	-	ko00000,ko01000,ko02000,ko02048	domain protein
HBCGBFBE_00742	3.41e-51	-	-	-	A	ko:K12092	ko05120,map05120	ko00000,ko00001,ko00002,ko02044	chlorophyll binding
HBCGBFBE_00743	1.37e-182	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HBCGBFBE_00744	5.88e-126	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HBCGBFBE_00745	9.43e-233	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
HBCGBFBE_00746	1.04e-214	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HBCGBFBE_00747	3.23e-75	-	-	-	S	-	-	-	Small secreted protein
HBCGBFBE_00748	2.95e-75	ytpP	-	-	CO	-	-	-	Thioredoxin
HBCGBFBE_00749	1.63e-152	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HBCGBFBE_00750	7.39e-64	-	-	-	S	-	-	-	Bacterial toxin of type II toxin-antitoxin system, YafQ
HBCGBFBE_00751	9.47e-48	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
HBCGBFBE_00752	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HBCGBFBE_00753	6.48e-154	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HBCGBFBE_00754	5.63e-151	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
HBCGBFBE_00755	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HBCGBFBE_00756	2.74e-204	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HBCGBFBE_00757	5.91e-129	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HBCGBFBE_00758	2.82e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HBCGBFBE_00759	3.31e-275	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
HBCGBFBE_00760	9.62e-219	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HBCGBFBE_00761	1.07e-110	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HBCGBFBE_00762	1.82e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HBCGBFBE_00763	2.23e-73	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HBCGBFBE_00764	3.17e-124	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
HBCGBFBE_00765	3.14e-278	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
HBCGBFBE_00766	5.4e-63	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
HBCGBFBE_00767	2.43e-158	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HBCGBFBE_00768	3.6e-146	yqeK	-	-	H	-	-	-	Hydrolase, HD family
HBCGBFBE_00769	1.9e-79	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HBCGBFBE_00770	1.1e-179	yqeM	-	-	Q	-	-	-	Methyltransferase
HBCGBFBE_00771	9.69e-274	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HBCGBFBE_00772	1.01e-129	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HBCGBFBE_00773	7.21e-39	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HBCGBFBE_00774	1.38e-155	csrR	-	-	K	-	-	-	response regulator
HBCGBFBE_00775	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HBCGBFBE_00776	0.0	potE	-	-	E	-	-	-	Amino Acid
HBCGBFBE_00777	7.99e-293	-	-	-	V	-	-	-	MatE
HBCGBFBE_00778	9.16e-91	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HBCGBFBE_00779	3.89e-215	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HBCGBFBE_00780	1.79e-60	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HBCGBFBE_00781	2.22e-185	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HBCGBFBE_00782	3.75e-119	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HBCGBFBE_00783	2.36e-77	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HBCGBFBE_00784	2.12e-251	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HBCGBFBE_00785	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HBCGBFBE_00786	6.92e-148	-	-	-	M	-	-	-	PFAM NLP P60 protein
HBCGBFBE_00787	2.06e-152	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HBCGBFBE_00788	8.31e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HBCGBFBE_00789	1.39e-92	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HBCGBFBE_00790	1.1e-126	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HBCGBFBE_00791	2.9e-31	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HBCGBFBE_00792	9.18e-31	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HBCGBFBE_00793	1.05e-174	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HBCGBFBE_00794	3.58e-93	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HBCGBFBE_00795	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HBCGBFBE_00796	5.12e-266	yacL	-	-	S	-	-	-	domain protein
HBCGBFBE_00797	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HBCGBFBE_00798	1.1e-125	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
HBCGBFBE_00799	3.33e-66	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
HBCGBFBE_00800	2.5e-162	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HBCGBFBE_00801	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HBCGBFBE_00802	3.51e-180	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HBCGBFBE_00803	5.84e-172	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HBCGBFBE_00804	9.62e-154	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HBCGBFBE_00805	4.28e-274	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HBCGBFBE_00806	6.27e-216	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HBCGBFBE_00807	3.04e-172	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HBCGBFBE_00808	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
HBCGBFBE_00809	3.18e-236	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
HBCGBFBE_00810	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HBCGBFBE_00812	5.75e-112	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HBCGBFBE_00813	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
HBCGBFBE_00814	5.27e-197	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HBCGBFBE_00815	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HBCGBFBE_00816	3.54e-165	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HBCGBFBE_00817	1.1e-171	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HBCGBFBE_00818	0.0	-	-	-	P	ko:K07085	-	ko00000	Predicted Permease Membrane Region
HBCGBFBE_00819	0.0	-	-	-	EGP	-	-	-	Major Facilitator
HBCGBFBE_00820	6.32e-143	-	-	-	-	-	-	-	-
HBCGBFBE_00823	1.85e-202	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HBCGBFBE_00824	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
HBCGBFBE_00827	9.11e-114	-	-	-	C	-	-	-	Oxidoreductase
HBCGBFBE_00828	3.41e-27	-	-	-	C	-	-	-	Oxidoreductase
HBCGBFBE_00829	2.89e-68	-	-	-	C	-	-	-	Oxidoreductase
HBCGBFBE_00830	3.88e-71	-	-	-	S	-	-	-	macrophage migration inhibitory factor
HBCGBFBE_00831	4.95e-86	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HBCGBFBE_00832	2.09e-115	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HBCGBFBE_00834	3.66e-286	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
HBCGBFBE_00835	1.01e-109	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
HBCGBFBE_00836	3.43e-282	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HBCGBFBE_00837	4.44e-91	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
HBCGBFBE_00838	2.58e-85	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
HBCGBFBE_00839	1.92e-91	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HBCGBFBE_00840	5.61e-222	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HBCGBFBE_00841	1.58e-264	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
HBCGBFBE_00842	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HBCGBFBE_00843	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
HBCGBFBE_00844	1.2e-206	-	-	-	S	-	-	-	EDD domain protein, DegV family
HBCGBFBE_00845	7.49e-124	-	-	-	-	-	-	-	-
HBCGBFBE_00846	1.24e-153	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HBCGBFBE_00847	2.07e-202	gspA	-	-	M	-	-	-	family 8
HBCGBFBE_00848	5.98e-206	-	-	-	S	-	-	-	Alpha beta hydrolase
HBCGBFBE_00849	7.5e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HBCGBFBE_00850	1.58e-190	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HBCGBFBE_00851	1.32e-91	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HBCGBFBE_00852	1.02e-51	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
HBCGBFBE_00853	7.05e-217	yvgN	-	-	C	-	-	-	Aldo keto reductase
HBCGBFBE_00854	7.79e-204	rlrB	-	-	K	-	-	-	LysR substrate binding domain protein
HBCGBFBE_00855	2.91e-109	-	-	-	C	-	-	-	Flavodoxin
HBCGBFBE_00856	6.14e-104	-	-	-	S	-	-	-	Cupin domain
HBCGBFBE_00857	9.49e-98	-	-	-	S	-	-	-	UPF0756 membrane protein
HBCGBFBE_00858	2.9e-309	-	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HBCGBFBE_00859	2.39e-98	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
HBCGBFBE_00860	5.51e-316	yhdP	-	-	S	-	-	-	Transporter associated domain
HBCGBFBE_00861	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
HBCGBFBE_00862	1.43e-185	-	-	-	S	-	-	-	DUF218 domain
HBCGBFBE_00863	3.39e-90	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HBCGBFBE_00864	1.3e-78	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HBCGBFBE_00865	6.28e-73	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HBCGBFBE_00866	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
HBCGBFBE_00867	2.04e-158	-	-	-	S	-	-	-	SNARE associated Golgi protein
HBCGBFBE_00868	2.11e-290	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HBCGBFBE_00869	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HBCGBFBE_00871	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HBCGBFBE_00872	1.4e-201	endA	-	-	V	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HBCGBFBE_00873	0.0	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HBCGBFBE_00874	2.29e-276	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HBCGBFBE_00875	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HBCGBFBE_00876	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HBCGBFBE_00877	1.51e-131	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HBCGBFBE_00878	2.86e-244	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HBCGBFBE_00879	1.45e-240	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HBCGBFBE_00880	7.54e-62	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HBCGBFBE_00881	6.15e-234	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
HBCGBFBE_00882	0.0	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HBCGBFBE_00883	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HBCGBFBE_00884	8.03e-58	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HBCGBFBE_00885	3.62e-100	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HBCGBFBE_00886	3.75e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HBCGBFBE_00887	6.87e-120	cvpA	-	-	S	-	-	-	Colicin V production protein
HBCGBFBE_00888	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HBCGBFBE_00889	2.86e-72	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HBCGBFBE_00890	1.01e-124	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HBCGBFBE_00891	2.58e-184	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HBCGBFBE_00892	3.33e-133	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HBCGBFBE_00893	9.81e-122	-	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HBCGBFBE_00894	3.62e-100	ykuL	-	-	S	-	-	-	(CBS) domain
HBCGBFBE_00895	1.1e-195	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HBCGBFBE_00896	6.23e-188	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
HBCGBFBE_00897	8.88e-71	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HBCGBFBE_00898	1.84e-75	-	-	-	-	-	-	-	-
HBCGBFBE_00899	1.08e-269	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HBCGBFBE_00900	1.63e-233	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HBCGBFBE_00901	1.15e-178	-	-	-	-	-	-	-	-
HBCGBFBE_00902	1.22e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
HBCGBFBE_00903	4.67e-232	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
HBCGBFBE_00904	2.49e-232	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
HBCGBFBE_00905	6.31e-62	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
HBCGBFBE_00906	1.01e-100	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
HBCGBFBE_00907	1.61e-54	-	-	-	-	-	-	-	-
HBCGBFBE_00908	9.32e-92	-	-	-	-	ko:K02248	-	ko00000,ko00002,ko02044	-
HBCGBFBE_00910	2.07e-185	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
HBCGBFBE_00911	4.18e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HBCGBFBE_00912	2.54e-145	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HBCGBFBE_00913	9.28e-121	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
HBCGBFBE_00914	2.87e-171	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HBCGBFBE_00915	1.03e-135	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
HBCGBFBE_00916	1.83e-149	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
HBCGBFBE_00917	8.58e-223	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HBCGBFBE_00918	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HBCGBFBE_00919	3.82e-157	-	-	-	S	-	-	-	repeat protein
HBCGBFBE_00920	6.67e-158	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
HBCGBFBE_00921	2.15e-286	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HBCGBFBE_00922	1.13e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
HBCGBFBE_00923	7.12e-275	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HBCGBFBE_00924	3.4e-162	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HBCGBFBE_00925	1.54e-33	-	-	-	-	-	-	-	-
HBCGBFBE_00926	2.48e-129	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HBCGBFBE_00927	5.69e-44	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HBCGBFBE_00928	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HBCGBFBE_00929	3.71e-109	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
HBCGBFBE_00930	1.97e-185	ylmH	-	-	S	-	-	-	S4 domain protein
HBCGBFBE_00931	3.2e-54	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
HBCGBFBE_00932	1.11e-92	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HBCGBFBE_00933	6.52e-289	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HBCGBFBE_00934	0.0	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HBCGBFBE_00935	8.69e-195	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HBCGBFBE_00936	1.45e-260	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HBCGBFBE_00937	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HBCGBFBE_00938	7.73e-230	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HBCGBFBE_00939	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HBCGBFBE_00940	3.47e-73	ftsL	-	-	D	-	-	-	Cell division protein FtsL
HBCGBFBE_00941	9.31e-224	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HBCGBFBE_00942	1.5e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HBCGBFBE_00943	7.76e-74	-	-	-	-	-	-	-	-
HBCGBFBE_00944	4.47e-16	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
HBCGBFBE_00945	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HBCGBFBE_00946	1.53e-123	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HBCGBFBE_00947	8.5e-208	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
HBCGBFBE_00948	6.56e-252	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HBCGBFBE_00950	4.92e-305	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HBCGBFBE_00951	7.38e-232	-	-	-	-	-	-	-	-
HBCGBFBE_00952	5.27e-169	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HBCGBFBE_00953	4.57e-307	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HBCGBFBE_00954	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HBCGBFBE_00955	8.26e-136	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HBCGBFBE_00956	5.37e-248	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HBCGBFBE_00957	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HBCGBFBE_00958	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HBCGBFBE_00959	1.15e-162	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HBCGBFBE_00960	2.23e-50	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HBCGBFBE_00961	2.13e-169	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HBCGBFBE_00962	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HBCGBFBE_00963	1.61e-271	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HBCGBFBE_00964	3.65e-109	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HBCGBFBE_00965	9.77e-170	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Belongs to the alpha-acetolactate decarboxylase family
HBCGBFBE_00966	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HBCGBFBE_00967	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HBCGBFBE_00968	5.55e-226	ydbI	-	-	K	-	-	-	AI-2E family transporter
HBCGBFBE_00969	1.15e-301	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HBCGBFBE_00970	1.85e-122	ribB	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HBCGBFBE_00971	1.91e-150	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HBCGBFBE_00972	1.83e-148	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HBCGBFBE_00973	3.95e-167	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HBCGBFBE_00974	1.87e-218	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HBCGBFBE_00975	4.45e-315	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HBCGBFBE_00976	6.04e-220	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HBCGBFBE_00977	2.79e-179	-	-	-	K	-	-	-	LysR substrate binding domain
HBCGBFBE_00978	1.17e-61	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
HBCGBFBE_00979	3.86e-281	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HBCGBFBE_00980	4.61e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
HBCGBFBE_00981	2.57e-227	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
HBCGBFBE_00982	6.06e-308	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HBCGBFBE_00983	1.76e-45	ywzB	-	-	S	-	-	-	Protein of unknown function (DUF1146)
HBCGBFBE_00984	1.05e-88	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HBCGBFBE_00985	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HBCGBFBE_00986	1.3e-212	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HBCGBFBE_00987	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HBCGBFBE_00988	6.84e-121	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HBCGBFBE_00989	1.07e-95	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HBCGBFBE_00990	1.26e-29	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HBCGBFBE_00991	4.63e-162	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HBCGBFBE_00992	2.3e-293	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
HBCGBFBE_00993	4.71e-166	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
HBCGBFBE_00994	6.71e-246	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
HBCGBFBE_00995	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HBCGBFBE_00996	6.68e-150	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HBCGBFBE_00997	6.33e-294	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HBCGBFBE_00998	1.55e-250	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HBCGBFBE_00999	1.86e-208	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HBCGBFBE_01000	1.73e-248	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HBCGBFBE_01001	6.8e-140	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HBCGBFBE_01002	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain
HBCGBFBE_01003	4.87e-173	-	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
HBCGBFBE_01004	1.97e-297	potE	-	-	U	ko:K03756,ko:K03758	-	ko00000,ko02000	Amino acid permease
HBCGBFBE_01005	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
HBCGBFBE_01006	1.77e-103	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HBCGBFBE_01007	1.25e-304	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
HBCGBFBE_01008	9.5e-239	ampC	-	-	V	-	-	-	Beta-lactamase
HBCGBFBE_01009	1.48e-247	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HBCGBFBE_01010	3.23e-222	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HBCGBFBE_01011	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HBCGBFBE_01012	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HBCGBFBE_01013	6.09e-176	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HBCGBFBE_01014	3.7e-199	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HBCGBFBE_01015	3.71e-76	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HBCGBFBE_01016	2.23e-236	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HBCGBFBE_01017	2.83e-69	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
HBCGBFBE_01018	2.14e-147	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HBCGBFBE_01019	2.71e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HBCGBFBE_01020	4.92e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HBCGBFBE_01021	5.87e-62	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HBCGBFBE_01022	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HBCGBFBE_01023	1.46e-117	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HBCGBFBE_01024	9.33e-48	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
HBCGBFBE_01025	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HBCGBFBE_01026	4.63e-255	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HBCGBFBE_01027	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HBCGBFBE_01028	3.1e-168	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
HBCGBFBE_01029	8.01e-129	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
HBCGBFBE_01030	6.58e-74	XK27_06915	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator PadR family
HBCGBFBE_01031	2.94e-65	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HBCGBFBE_01033	2.91e-65	-	-	-	-	-	-	-	-
HBCGBFBE_01034	2.46e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HBCGBFBE_01035	3.6e-107	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HBCGBFBE_01036	8.32e-223	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HBCGBFBE_01037	1.28e-27	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HBCGBFBE_01038	1.62e-314	-	-	-	M	-	-	-	Glycosyl transferase family group 2
HBCGBFBE_01040	1.86e-288	aadAT	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	Aminotransferase, class I
HBCGBFBE_01041	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Levansucrase/Invertase
HBCGBFBE_01042	7.24e-204	rssA	-	-	S	-	-	-	Phospholipase, patatin family
HBCGBFBE_01043	1.15e-152	-	-	-	L	-	-	-	Integrase
HBCGBFBE_01044	7.66e-196	-	-	-	EG	-	-	-	EamA-like transporter family
HBCGBFBE_01045	2.82e-299	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HBCGBFBE_01046	9.45e-168	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase
HBCGBFBE_01047	7.3e-131	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase molybdenum cofactor assembly chaperone
HBCGBFBE_01048	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
HBCGBFBE_01049	0.0	narZ	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HBCGBFBE_01050	1.92e-238	moeB	2.7.7.80	-	H	ko:K21029	ko04122,map04122	ko00000,ko00001,ko01000	ThiF family
HBCGBFBE_01051	1.65e-107	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
HBCGBFBE_01052	2.19e-291	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	MoeA N-terminal region (domain I and II)
HBCGBFBE_01053	9.66e-110	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
HBCGBFBE_01054	2.03e-136	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HBCGBFBE_01055	1.56e-60	-	-	-	-	-	-	-	-
HBCGBFBE_01056	9.18e-243	nreB	2.7.13.3	-	F	ko:K07683	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Sensor histidine kinase
HBCGBFBE_01057	2.22e-151	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
HBCGBFBE_01058	3.11e-26	-	-	-	-	-	-	-	-
HBCGBFBE_01059	9.46e-235	-	-	-	-	-	-	-	-
HBCGBFBE_01060	4.74e-213	-	-	-	H	-	-	-	geranyltranstransferase activity
HBCGBFBE_01061	5.25e-279	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	Transporter, major facilitator family protein
HBCGBFBE_01062	4.04e-48	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	ThiS family
HBCGBFBE_01063	3.25e-84	moaE	2.8.1.12	-	H	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	MoaE protein
HBCGBFBE_01064	7.28e-101	-	-	-	S	-	-	-	Flavodoxin
HBCGBFBE_01065	2.42e-164	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBCGBFBE_01066	4.82e-180	fecE	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HBCGBFBE_01067	8.36e-233	fecB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HBCGBFBE_01068	8.62e-225	-	-	-	-	-	-	-	-
HBCGBFBE_01069	1.1e-95	-	-	-	-	-	-	-	-
HBCGBFBE_01070	2.25e-105	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K07000,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
HBCGBFBE_01071	2.87e-250	-	-	-	S	-	-	-	Protein of unknown function (DUF3114)
HBCGBFBE_01072	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HBCGBFBE_01073	1.86e-213	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HBCGBFBE_01074	1.25e-136	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HBCGBFBE_01075	3.8e-80	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
HBCGBFBE_01076	5.34e-245	mocA	-	-	S	-	-	-	Oxidoreductase
HBCGBFBE_01077	1.83e-295	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
HBCGBFBE_01079	2.09e-266	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HBCGBFBE_01080	1.09e-65	-	-	-	-	-	-	-	-
HBCGBFBE_01081	4.94e-88	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
HBCGBFBE_01082	4.7e-103	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HBCGBFBE_01083	1e-215	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
HBCGBFBE_01084	3.98e-280	arcT	-	-	E	-	-	-	Aminotransferase
HBCGBFBE_01085	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
HBCGBFBE_01086	0.0	potE	-	-	E	-	-	-	Amino Acid
HBCGBFBE_01087	7.47e-203	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HBCGBFBE_01088	1.26e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
HBCGBFBE_01089	2.53e-42	-	-	-	-	-	-	-	-
HBCGBFBE_01090	4.75e-174	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
HBCGBFBE_01091	1.84e-187	cps1D	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HBCGBFBE_01092	1.38e-225	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
HBCGBFBE_01093	1.15e-152	-	-	-	M	-	-	-	Bacterial sugar transferase
HBCGBFBE_01094	2.78e-275	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HBCGBFBE_01095	8.14e-303	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HBCGBFBE_01096	5.68e-190	-	-	GT4	M	ko:K02840	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Glycosyl transferases group 1
HBCGBFBE_01097	7.08e-168	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HBCGBFBE_01098	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HBCGBFBE_01099	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HBCGBFBE_01100	5.67e-178	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HBCGBFBE_01102	6.17e-286	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HBCGBFBE_01103	3.42e-278	nupG	-	-	F	ko:K03317,ko:K11535,ko:K16323	-	ko00000,ko02000	Nucleoside transporter
HBCGBFBE_01104	2.76e-217	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
HBCGBFBE_01105	5.97e-208	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
HBCGBFBE_01106	1.54e-163	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HBCGBFBE_01107	3.73e-200	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HBCGBFBE_01108	2.79e-178	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
HBCGBFBE_01109	1.96e-197	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HBCGBFBE_01110	5.8e-43	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
HBCGBFBE_01111	6.1e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HBCGBFBE_01112	7.35e-174	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
HBCGBFBE_01113	9.74e-154	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HBCGBFBE_01114	1.09e-296	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HBCGBFBE_01115	1.58e-300	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
HBCGBFBE_01116	3.27e-167	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
HBCGBFBE_01117	1.32e-219	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	sugar-binding domain protein
HBCGBFBE_01118	8.13e-263	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HBCGBFBE_01119	3.27e-159	vanR	-	-	K	-	-	-	response regulator
HBCGBFBE_01120	5.47e-261	hpk31	-	-	T	-	-	-	Histidine kinase
HBCGBFBE_01121	4.95e-195	-	-	-	E	-	-	-	AzlC protein
HBCGBFBE_01122	4.05e-70	-	-	-	S	-	-	-	branched-chain amino acid
HBCGBFBE_01123	5.43e-196	-	-	-	-	-	-	-	-
HBCGBFBE_01124	1.95e-307	-	-	-	M	-	-	-	Glycosyl transferase
HBCGBFBE_01125	4.68e-282	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
HBCGBFBE_01126	7.41e-177	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
HBCGBFBE_01127	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
HBCGBFBE_01128	3.91e-304	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
HBCGBFBE_01129	2.8e-152	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
HBCGBFBE_01130	9.27e-115	-	-	-	Q	-	-	-	Methyltransferase
HBCGBFBE_01131	1.62e-294	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HBCGBFBE_01132	2.81e-230	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
HBCGBFBE_01133	3.77e-216	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HBCGBFBE_01134	7.45e-122	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HBCGBFBE_01135	2.89e-230	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HBCGBFBE_01136	5.26e-174	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HBCGBFBE_01137	9.73e-215	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
HBCGBFBE_01138	4.29e-227	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
HBCGBFBE_01139	0.0	arcD	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
HBCGBFBE_01140	0.0	arcT	-	-	E	-	-	-	Dipeptidase
HBCGBFBE_01141	3.66e-274	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
HBCGBFBE_01142	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
HBCGBFBE_01143	3.66e-183	-	-	-	V	-	-	-	Beta-lactamase enzyme family
HBCGBFBE_01145	7.25e-301	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
HBCGBFBE_01146	4.38e-72	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HBCGBFBE_01147	3.78e-169	yceF	-	-	P	ko:K05794	-	ko00000	membrane
HBCGBFBE_01148	8.16e-212	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HBCGBFBE_01149	2.35e-215	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HBCGBFBE_01150	0.0	-	-	-	L	-	-	-	Transposase
HBCGBFBE_01151	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HBCGBFBE_01152	4.79e-307	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
HBCGBFBE_01153	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HBCGBFBE_01154	9.8e-305	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
HBCGBFBE_01155	3.39e-33	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
HBCGBFBE_01156	3.18e-160	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
HBCGBFBE_01157	1.77e-56	-	-	-	-	-	-	-	-
HBCGBFBE_01158	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HBCGBFBE_01159	2.84e-264	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	dehydrogenase
HBCGBFBE_01160	2.56e-188	-	-	-	S	-	-	-	Alpha beta hydrolase
HBCGBFBE_01161	1.02e-279	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HBCGBFBE_01162	1.93e-131	-	-	-	-	-	-	-	-
HBCGBFBE_01164	5.09e-162	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HBCGBFBE_01165	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HBCGBFBE_01166	7.33e-253	-	-	-	EGP	-	-	-	Major Facilitator
HBCGBFBE_01167	6.26e-115	ymdB	-	-	S	-	-	-	Macro domain protein
HBCGBFBE_01168	2.13e-142	-	-	-	K	-	-	-	Helix-turn-helix domain
HBCGBFBE_01169	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HBCGBFBE_01170	4.95e-63	-	-	-	-	-	-	-	-
HBCGBFBE_01171	8.89e-306	-	-	-	S	-	-	-	Putative metallopeptidase domain
HBCGBFBE_01172	1.46e-261	-	-	-	S	-	-	-	associated with various cellular activities
HBCGBFBE_01173	1.92e-153	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HBCGBFBE_01174	3.47e-85	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
HBCGBFBE_01176	6.8e-151	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
HBCGBFBE_01177	2.84e-73	-	-	-	-	-	-	-	-
HBCGBFBE_01179	1.97e-131	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HBCGBFBE_01180	1.62e-34	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HBCGBFBE_01181	5.87e-65	-	-	-	-	-	-	-	-
HBCGBFBE_01183	5.28e-262	yngD	-	-	S	ko:K07097	-	ko00000	DHHA1 domain
HBCGBFBE_01184	6.07e-292	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
HBCGBFBE_01185	1.8e-316	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HBCGBFBE_01186	7.28e-138	-	-	-	NU	-	-	-	mannosyl-glycoprotein
HBCGBFBE_01187	8.04e-184	-	-	-	S	-	-	-	Putative ABC-transporter type IV
HBCGBFBE_01188	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HBCGBFBE_01189	5.27e-64	-	-	-	-	-	-	-	-
HBCGBFBE_01190	1.05e-271	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
HBCGBFBE_01191	3e-221	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
HBCGBFBE_01192	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HBCGBFBE_01193	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HBCGBFBE_01194	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HBCGBFBE_01195	1.12e-135	-	-	-	K	-	-	-	PFAM GCN5-related N-acetyltransferase
HBCGBFBE_01197	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
HBCGBFBE_01198	2.49e-43	-	-	-	-	-	-	-	-
HBCGBFBE_01199	6.83e-274	-	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HBCGBFBE_01200	3.24e-226	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HBCGBFBE_01201	6.86e-98	-	-	-	O	-	-	-	OsmC-like protein
HBCGBFBE_01202	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HBCGBFBE_01203	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HBCGBFBE_01204	1.76e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HBCGBFBE_01205	1.76e-112	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
HBCGBFBE_01206	3.15e-153	dltr	-	-	K	-	-	-	response regulator
HBCGBFBE_01207	1.13e-289	sptS	-	-	T	-	-	-	Histidine kinase
HBCGBFBE_01208	1.41e-265	-	-	-	P	-	-	-	Voltage gated chloride channel
HBCGBFBE_01209	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HBCGBFBE_01210	6.13e-175	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
HBCGBFBE_01211	2.1e-214	-	-	-	C	-	-	-	Aldo keto reductase
HBCGBFBE_01212	1.86e-63	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
HBCGBFBE_01213	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
HBCGBFBE_01214	7.6e-113	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
HBCGBFBE_01215	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
HBCGBFBE_01216	6.39e-234	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HBCGBFBE_01217	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HBCGBFBE_01218	2.81e-118	-	-	-	-	-	-	-	-
HBCGBFBE_01219	4.65e-123	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HBCGBFBE_01221	3.25e-18	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
HBCGBFBE_01222	7.96e-97	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
HBCGBFBE_01223	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HBCGBFBE_01224	2.18e-79	-	-	-	-	-	-	-	-
HBCGBFBE_01225	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HBCGBFBE_01226	7.01e-244	-	-	-	E	-	-	-	Zinc-binding dehydrogenase
HBCGBFBE_01227	2.72e-113	-	-	-	K	-	-	-	transcriptional regulator (TetR family)
HBCGBFBE_01228	2.39e-234	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HBCGBFBE_01229	4.22e-148	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HBCGBFBE_01230	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HBCGBFBE_01231	1.18e-50	-	-	-	-	-	-	-	-
HBCGBFBE_01232	4.57e-65	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
HBCGBFBE_01233	7.15e-315	-	3.2.1.17	CBM50	NU	ko:K01185,ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HBCGBFBE_01234	3.11e-220	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
HBCGBFBE_01235	2.14e-32	-	-	-	-	-	-	-	-
HBCGBFBE_01236	1.03e-146	-	-	-	-	-	-	-	-
HBCGBFBE_01237	4.99e-273	yttB	-	-	EGP	-	-	-	Major Facilitator
HBCGBFBE_01238	6.55e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HBCGBFBE_01239	2.02e-112	-	-	-	-	-	-	-	-
HBCGBFBE_01240	4.3e-142	nnrE	5.1.99.6	-	H	ko:K17759	-	ko00000,ko01000	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
HBCGBFBE_01241	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HBCGBFBE_01242	2.22e-151	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
HBCGBFBE_01243	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
HBCGBFBE_01244	7.21e-205	-	-	-	K	-	-	-	LysR family
HBCGBFBE_01245	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HBCGBFBE_01246	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HBCGBFBE_01247	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HBCGBFBE_01248	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
HBCGBFBE_01249	5.46e-207	mleR	-	-	K	-	-	-	LysR family
HBCGBFBE_01250	2.87e-144	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HBCGBFBE_01251	1.35e-263	adh	1.1.1.1	-	C	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding alcohol dehydrogenase family protein
HBCGBFBE_01252	0.0	-	-	-	L	-	-	-	PFAM plasmid pRiA4b ORF-3 family protein
HBCGBFBE_01253	7.42e-214	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HBCGBFBE_01254	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
HBCGBFBE_01255	1.36e-35	-	-	-	-	-	-	-	-
HBCGBFBE_01256	1.5e-254	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HBCGBFBE_01257	1.08e-96	-	-	-	-	-	-	-	-
HBCGBFBE_01258	9.29e-290	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HBCGBFBE_01259	1.72e-167	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
HBCGBFBE_01260	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HBCGBFBE_01261	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HBCGBFBE_01262	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HBCGBFBE_01263	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HBCGBFBE_01264	7.33e-315	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
HBCGBFBE_01265	2.44e-147	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HBCGBFBE_01266	4.4e-114	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase, GNAT family
HBCGBFBE_01267	3.88e-205	-	-	-	S	-	-	-	reductase
HBCGBFBE_01269	0.0	-	-	-	S	-	-	-	amidohydrolase
HBCGBFBE_01270	0.0	-	-	-	K	-	-	-	Aminotransferase class I and II
HBCGBFBE_01271	2.19e-153	azlC	-	-	E	-	-	-	azaleucine resistance protein AzlC
HBCGBFBE_01272	4.53e-66	azlD	-	-	E	-	-	-	Branched-chain amino acid transport
HBCGBFBE_01273	6.38e-151	-	-	-	S	-	-	-	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
HBCGBFBE_01275	1.08e-89	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
HBCGBFBE_01276	1.3e-50	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
HBCGBFBE_01277	5.66e-158	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
HBCGBFBE_01278	7.15e-122	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HBCGBFBE_01279	1.26e-243	flp	-	-	V	-	-	-	Beta-lactamase
HBCGBFBE_01280	2.96e-172	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HBCGBFBE_01281	1.39e-76	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HBCGBFBE_01282	7.96e-21	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
HBCGBFBE_01283	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HBCGBFBE_01284	1.41e-263	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HBCGBFBE_01285	1.13e-104	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
HBCGBFBE_01286	9.78e-14	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
HBCGBFBE_01287	5.41e-47	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
HBCGBFBE_01288	1.7e-261	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HBCGBFBE_01289	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HBCGBFBE_01290	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HBCGBFBE_01291	4.55e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HBCGBFBE_01292	5.93e-114	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HBCGBFBE_01293	9.36e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HBCGBFBE_01294	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HBCGBFBE_01295	1.25e-97	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HBCGBFBE_01296	6.04e-307	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HBCGBFBE_01297	1.08e-268	yttB	-	-	EGP	-	-	-	Major Facilitator
HBCGBFBE_01298	3.85e-72	-	-	-	-	-	-	-	-
HBCGBFBE_01299	1.86e-210	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
HBCGBFBE_01300	3.44e-12	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
HBCGBFBE_01301	3.94e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HBCGBFBE_01302	9.25e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HBCGBFBE_01303	6.12e-182	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HBCGBFBE_01304	1.43e-181	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HBCGBFBE_01305	9.73e-195	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HBCGBFBE_01306	1.23e-186	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HBCGBFBE_01307	8.08e-83	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HBCGBFBE_01308	8.91e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HBCGBFBE_01309	1.62e-83	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HBCGBFBE_01310	1.54e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HBCGBFBE_01311	5.79e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
HBCGBFBE_01312	9.82e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HBCGBFBE_01313	4.52e-161	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HBCGBFBE_01314	2.88e-306	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HBCGBFBE_01315	6.05e-93	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HBCGBFBE_01316	5.94e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HBCGBFBE_01317	5.95e-112	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HBCGBFBE_01318	5.03e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HBCGBFBE_01319	1.06e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HBCGBFBE_01320	1.54e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HBCGBFBE_01321	4.97e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HBCGBFBE_01322	7.42e-125	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HBCGBFBE_01323	2.58e-65	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HBCGBFBE_01324	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HBCGBFBE_01325	1.1e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HBCGBFBE_01326	5.49e-38	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HBCGBFBE_01327	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HBCGBFBE_01328	9.81e-157	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HBCGBFBE_01329	8.8e-70	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HBCGBFBE_01330	5.72e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HBCGBFBE_01331	1.16e-203	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HBCGBFBE_01332	3.61e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HBCGBFBE_01333	6.64e-139	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HBCGBFBE_01334	5.45e-153	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HBCGBFBE_01335	1.28e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HBCGBFBE_01336	4.46e-180	budC	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
HBCGBFBE_01337	3.07e-149	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
HBCGBFBE_01338	3.91e-130	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HBCGBFBE_01339	8.91e-270	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HBCGBFBE_01340	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HBCGBFBE_01341	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HBCGBFBE_01342	1.11e-260	camS	-	-	S	-	-	-	sex pheromone
HBCGBFBE_01343	2.26e-65	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HBCGBFBE_01344	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HBCGBFBE_01345	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HBCGBFBE_01346	5.06e-237	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
HBCGBFBE_01347	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HBCGBFBE_01348	3.25e-60	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HBCGBFBE_01349	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
HBCGBFBE_01350	5.98e-14	-	-	-	-	-	-	-	-
HBCGBFBE_01351	3.91e-40	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HBCGBFBE_01352	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HBCGBFBE_01353	5.28e-225	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HBCGBFBE_01354	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
HBCGBFBE_01355	6.57e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Peroxiredoxin
HBCGBFBE_01356	5.11e-188	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HBCGBFBE_01357	1.1e-157	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
HBCGBFBE_01360	2.48e-57	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HBCGBFBE_01361	9.61e-213	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HBCGBFBE_01362	1.48e-290	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HBCGBFBE_01363	2.6e-167	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HBCGBFBE_01364	9.02e-201	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HBCGBFBE_01365	1.81e-225	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HBCGBFBE_01366	4.18e-168	-	-	-	F	-	-	-	glutamine amidotransferase
HBCGBFBE_01367	1.74e-85	-	-	-	-	-	-	-	-
HBCGBFBE_01368	2.22e-145	-	-	-	GM	-	-	-	NAD(P)H-binding
HBCGBFBE_01369	3.43e-110	-	-	-	S	-	-	-	membrane
HBCGBFBE_01370	1.28e-105	-	-	-	S	-	-	-	membrane
HBCGBFBE_01371	3.14e-118	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
HBCGBFBE_01372	7.26e-208	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HBCGBFBE_01373	3.02e-52	-	-	-	K	-	-	-	Transcriptional regulator
HBCGBFBE_01374	5.61e-75	-	-	-	K	-	-	-	Transcriptional regulator
HBCGBFBE_01375	5.69e-235	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
HBCGBFBE_01376	1.45e-214	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
HBCGBFBE_01377	1.39e-83	-	-	-	GM	-	-	-	NAD(P)H-binding
HBCGBFBE_01378	1.02e-120	-	-	-	K	-	-	-	Virulence activator alpha C-term
HBCGBFBE_01379	2.49e-120	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
HBCGBFBE_01380	2.05e-195	-	-	-	S	-	-	-	Alpha beta hydrolase
HBCGBFBE_01381	8.09e-44	-	-	-	S	ko:K06889	-	ko00000	thiolester hydrolase activity
HBCGBFBE_01382	7.41e-114	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
HBCGBFBE_01383	2.15e-203	lysR	-	-	K	-	-	-	Transcriptional regulator
HBCGBFBE_01384	2.67e-111	-	-	-	C	-	-	-	Flavodoxin
HBCGBFBE_01385	1.12e-210	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
HBCGBFBE_01386	2.32e-210	-	-	-	K	-	-	-	COG COG0846 NAD-dependent protein deacetylases, SIR2 family
HBCGBFBE_01387	4.09e-99	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HBCGBFBE_01388	1.2e-106	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HBCGBFBE_01389	1.16e-72	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
HBCGBFBE_01390	2.84e-201	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HBCGBFBE_01391	1.18e-276	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HBCGBFBE_01392	8.1e-264	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HBCGBFBE_01393	7.99e-163	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
HBCGBFBE_01394	1.63e-53	-	-	-	GM	ko:K19426	-	ko00000,ko01000	Polysaccharide pyruvyl transferase
HBCGBFBE_01395	1.13e-36	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HBCGBFBE_01397	7.61e-62	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HBCGBFBE_01398	2.6e-50	epsH	-	GT2	S	ko:K19425	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
HBCGBFBE_01399	1.1e-103	-	-	GT4	G	ko:K19422	-	ko00000,ko01000	Glycosyl transferase 4-like domain
HBCGBFBE_01400	3.14e-64	capM	-	-	M	ko:K13012	-	ko00000,ko01005	Bacterial sugar transferase
HBCGBFBE_01401	5.88e-156	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HBCGBFBE_01402	5.34e-189	epsB	-	-	M	-	-	-	biosynthesis protein
HBCGBFBE_01403	9.12e-218	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HBCGBFBE_01404	7.34e-86	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HBCGBFBE_01405	2.15e-121	-	-	-	-	-	-	-	-
HBCGBFBE_01409	2.44e-247	gtf2	-	-	M	-	-	-	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
HBCGBFBE_01410	1.92e-284	gtf1	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HBCGBFBE_01411	0.0	secA2	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HBCGBFBE_01412	1.52e-206	asp3	-	-	S	ko:K12270	-	ko00000,ko02044	Accessory Sec secretory system ASP3
HBCGBFBE_01413	0.0	asp2	-	-	S	ko:K12269	-	ko00000,ko02044	Accessory Sec system GspB-transporter
HBCGBFBE_01414	0.0	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HBCGBFBE_01415	6.21e-266	secY2	-	-	U	-	-	-	Part of the accessory SecA2 SecY2 system specifically required for export of
HBCGBFBE_01416	4.59e-248	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HBCGBFBE_01418	6.91e-234	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HBCGBFBE_01419	6.45e-49	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HBCGBFBE_01420	1.22e-197	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HBCGBFBE_01421	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HBCGBFBE_01422	5.1e-121	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HBCGBFBE_01423	4.11e-225	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HBCGBFBE_01424	2.6e-234	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
HBCGBFBE_01425	1.55e-109	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HBCGBFBE_01426	2.11e-80	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
HBCGBFBE_01427	1.08e-218	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HBCGBFBE_01428	2.14e-189	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HBCGBFBE_01429	2.14e-234	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HBCGBFBE_01430	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HBCGBFBE_01431	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HBCGBFBE_01432	2.09e-265	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HBCGBFBE_01433	0.0	cadA	-	-	P	-	-	-	P-type ATPase
HBCGBFBE_01434	5.23e-276	-	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Metalloenzyme superfamily
HBCGBFBE_01435	4.44e-11	-	-	-	-	-	-	-	-
HBCGBFBE_01436	7.45e-197	-	-	-	GM	-	-	-	NAD(P)H-binding
HBCGBFBE_01437	3.87e-97	ywnA	-	-	K	-	-	-	Transcriptional regulator
HBCGBFBE_01438	1.77e-207	proWY	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, QAT family
HBCGBFBE_01439	2.35e-139	proWZ	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HBCGBFBE_01440	8.34e-180	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HBCGBFBE_01441	1.96e-138	-	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
HBCGBFBE_01442	3.53e-100	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HBCGBFBE_01443	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HBCGBFBE_01444	7.15e-278	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HBCGBFBE_01445	5.25e-140	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HBCGBFBE_01446	4.92e-244	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HBCGBFBE_01447	2.06e-198	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HBCGBFBE_01448	5.14e-217	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HBCGBFBE_01449	6.55e-216	ganB	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
HBCGBFBE_01450	1.28e-83	-	-	-	S	-	-	-	dextransucrase activity
HBCGBFBE_01452	1.31e-130	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HBCGBFBE_01458	8.85e-147	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HBCGBFBE_01459	2.49e-87	-	-	-	S	-	-	-	Belongs to the HesB IscA family
HBCGBFBE_01460	9.14e-66	-	-	-	-	-	-	-	-
HBCGBFBE_01462	7.63e-117	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HBCGBFBE_01463	2.71e-81	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HBCGBFBE_01464	3.09e-35	-	-	-	-	-	-	-	-
HBCGBFBE_01465	1.14e-124	-	-	-	-	-	-	-	-
HBCGBFBE_01466	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HBCGBFBE_01467	3.99e-233	-	-	-	K	ko:K02525	-	ko00000,ko03000	Transcriptional regulator, LacI family
HBCGBFBE_01468	8.21e-290	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
HBCGBFBE_01469	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HBCGBFBE_01470	5.91e-125	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HBCGBFBE_01471	1.09e-62	-	-	-	-	-	-	-	-
HBCGBFBE_01472	6.77e-230	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
HBCGBFBE_01473	2.58e-174	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
HBCGBFBE_01474	1.26e-60	-	-	-	-	-	-	-	-
HBCGBFBE_01475	1.86e-103	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
HBCGBFBE_01476	1.48e-178	butA	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
HBCGBFBE_01477	4.03e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HBCGBFBE_01478	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HBCGBFBE_01479	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HBCGBFBE_01480	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HBCGBFBE_01481	0.0	-	-	-	M	-	-	-	domain protein
HBCGBFBE_01482	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
HBCGBFBE_01483	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HBCGBFBE_01484	8.53e-95	-	-	-	-	-	-	-	-
HBCGBFBE_01486	7.54e-115	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HBCGBFBE_01487	1.81e-226	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HBCGBFBE_01488	5.79e-117	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
HBCGBFBE_01489	1.84e-282	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
HBCGBFBE_01490	2.52e-196	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
HBCGBFBE_01491	4.13e-192	yycI	-	-	S	-	-	-	YycH protein
HBCGBFBE_01492	2.41e-315	yycH	-	-	S	-	-	-	YycH protein
HBCGBFBE_01493	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HBCGBFBE_01494	3.69e-168	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HBCGBFBE_01496	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HBCGBFBE_01497	6.55e-97	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
HBCGBFBE_01499	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HBCGBFBE_01500	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HBCGBFBE_01501	3.21e-160	-	-	-	L	-	-	-	Type I restriction modification DNA specificity domain
HBCGBFBE_01502	1.46e-171	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HBCGBFBE_01503	3.17e-84	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain protein
HBCGBFBE_01504	6.75e-215	-	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
HBCGBFBE_01505	2.93e-117	mrr2	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
HBCGBFBE_01506	0.0	-	-	-	L	-	-	-	PLD-like domain
HBCGBFBE_01508	6.48e-153	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HBCGBFBE_01509	5.18e-27	-	-	-	-	-	-	-	-
HBCGBFBE_01510	4.9e-118	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HBCGBFBE_01511	1.05e-102	-	-	-	K	-	-	-	LytTr DNA-binding domain
HBCGBFBE_01512	1.53e-97	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HBCGBFBE_01513	7.88e-215	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
HBCGBFBE_01514	6.2e-214	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
HBCGBFBE_01515	3.43e-96	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
HBCGBFBE_01516	1.25e-157	pnb	-	-	C	-	-	-	nitroreductase
HBCGBFBE_01517	8.65e-119	-	-	-	-	-	-	-	-
HBCGBFBE_01518	1.16e-114	XK27_07210	-	-	S	-	-	-	B3 4 domain
HBCGBFBE_01519	2.64e-315	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
HBCGBFBE_01520	1.52e-205	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
HBCGBFBE_01521	3.44e-47	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HBCGBFBE_01523	3.81e-62	-	-	-	-	-	-	-	-
HBCGBFBE_01525	2.24e-215	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
HBCGBFBE_01526	2.77e-55	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
HBCGBFBE_01527	6.2e-271	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
HBCGBFBE_01528	1.82e-316	-	-	-	E	ko:K03294	-	ko00000	amino acid
HBCGBFBE_01529	1.63e-233	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HBCGBFBE_01531	1.94e-269	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
HBCGBFBE_01532	4.51e-54	-	-	-	S	-	-	-	Cytochrome B5
HBCGBFBE_01533	8.47e-08	-	-	-	S	-	-	-	Cytochrome B5
HBCGBFBE_01534	2.3e-52	-	-	-	S	-	-	-	Cytochrome B5
HBCGBFBE_01535	5.36e-92	-	-	-	S	ko:K02348	-	ko00000	Gnat family
HBCGBFBE_01536	7.48e-155	-	-	-	GM	-	-	-	NmrA-like family
HBCGBFBE_01537	6.47e-68	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HBCGBFBE_01538	3.2e-138	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
HBCGBFBE_01539	5.2e-56	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HBCGBFBE_01540	2.59e-34	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HBCGBFBE_01541	7.97e-292	-	-	-	-	-	-	-	-
HBCGBFBE_01542	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
HBCGBFBE_01543	2.63e-264	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HBCGBFBE_01544	1.16e-216	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HBCGBFBE_01545	2.71e-186	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
HBCGBFBE_01546	0.0	snf	-	-	KL	-	-	-	domain protein
HBCGBFBE_01548	4.74e-51	-	-	-	-	ko:K18829	-	ko00000,ko02048	-
HBCGBFBE_01549	4.36e-90	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	Toxin-antitoxin system, toxin component, MazF family
HBCGBFBE_01550	5.14e-70	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
HBCGBFBE_01551	9.42e-57	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
HBCGBFBE_01552	2.71e-103	usp5	-	-	T	-	-	-	universal stress protein
HBCGBFBE_01553	2.7e-104	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
HBCGBFBE_01554	8.33e-294	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HBCGBFBE_01555	2.56e-133	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
HBCGBFBE_01556	1.97e-231	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HBCGBFBE_01557	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HBCGBFBE_01558	8.5e-287	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HBCGBFBE_01559	2.71e-234	celE3	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HBCGBFBE_01560	5.69e-189	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HBCGBFBE_01561	5.55e-121	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HBCGBFBE_01562	1.21e-48	-	-	-	-	-	-	-	-
HBCGBFBE_01563	1.24e-68	-	-	-	-	-	-	-	-
HBCGBFBE_01564	2.24e-261	-	-	-	-	-	-	-	-
HBCGBFBE_01567	0.0	-	-	-	LV	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
HBCGBFBE_01572	7.89e-168	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
HBCGBFBE_01573	1.55e-176	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
HBCGBFBE_01574	1.39e-182	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HBCGBFBE_01575	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
HBCGBFBE_01576	4.61e-97	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HBCGBFBE_01577	6.2e-96	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HBCGBFBE_01578	1.21e-286	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HBCGBFBE_01579	1.22e-166	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HBCGBFBE_01580	3.95e-203	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
HBCGBFBE_01581	2.51e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HBCGBFBE_01582	5.4e-226	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HBCGBFBE_01583	2.35e-101	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HBCGBFBE_01584	1.76e-94	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HBCGBFBE_01586	9.39e-256	xerS	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HBCGBFBE_01587	4.51e-219	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HBCGBFBE_01588	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HBCGBFBE_01589	1.45e-314	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HBCGBFBE_01590	2.66e-111	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HBCGBFBE_01591	1.64e-283	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HBCGBFBE_01592	9.32e-223	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HBCGBFBE_01593	1.43e-177	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HBCGBFBE_01594	1.62e-276	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HBCGBFBE_01595	2.58e-254	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HBCGBFBE_01596	5.77e-104	-	-	-	KT	ko:K02647	-	ko00000,ko03000	Putative sugar diacid recognition
HBCGBFBE_01597	1.96e-166	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
HBCGBFBE_01598	1.01e-133	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
HBCGBFBE_01599	2.12e-253	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HBCGBFBE_01600	5.14e-170	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HBCGBFBE_01601	2.56e-290	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HBCGBFBE_01602	3.49e-175	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HBCGBFBE_01603	1.82e-181	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
HBCGBFBE_01604	6.98e-286	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HBCGBFBE_01605	4.85e-232	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HBCGBFBE_01606	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
HBCGBFBE_01607	1.41e-78	-	-	-	L	-	-	-	Resolvase, N terminal domain
HBCGBFBE_01611	6.95e-06	-	-	-	S	-	-	-	Protein of unknown function, DUF536
HBCGBFBE_01612	1.65e-76	repB	-	-	L	-	-	-	Initiator Replication protein
HBCGBFBE_01613	1.11e-81	-	-	-	S	-	-	-	Conjugative transposon protein TcpC
HBCGBFBE_01614	0.0	tetM	-	-	J	ko:K18220	-	br01600,ko00000,ko01504	of the elongation factors EF-G and EF-2. Tet(M) and Tet(O) catalyze the release of tetracycline (Tc) from the ribosome
HBCGBFBE_01615	1.43e-307	tetL	-	-	EGP	ko:K08168	-	ko00000,ko00002,ko01504,ko02000	Major Facilitator Superfamily
HBCGBFBE_01616	1.35e-182	-	-	-	G	-	-	-	MucBP domain
HBCGBFBE_01617	7.43e-129	-	-	-	S	-	-	-	Pfam:DUF3816
HBCGBFBE_01618	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HBCGBFBE_01619	1.38e-37	-	-	-	-	-	-	-	-
HBCGBFBE_01620	3.69e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
HBCGBFBE_01621	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HBCGBFBE_01622	2.99e-289	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HBCGBFBE_01623	1.09e-250	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HBCGBFBE_01624	3.8e-228	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HBCGBFBE_01625	3.28e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF1797)
HBCGBFBE_01626	3.43e-85	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HBCGBFBE_01627	2.02e-305	-	-	-	EGP	-	-	-	MFS transporter, metabolite H symporter (MHS) family protein
HBCGBFBE_01628	8.61e-168	-	-	-	IQ	-	-	-	dehydrogenase reductase
HBCGBFBE_01629	3.88e-50	-	-	-	-	-	-	-	-
HBCGBFBE_01630	1.63e-148	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HBCGBFBE_01631	2.69e-51	-	-	-	S	-	-	-	Cytochrome b5-like Heme/Steroid binding domain
HBCGBFBE_01632	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HBCGBFBE_01633	6.86e-195	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HBCGBFBE_01635	1.24e-132	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
HBCGBFBE_01636	1.26e-82	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
HBCGBFBE_01637	0.0	-	-	-	S	-	-	-	SEC-C Motif Domain Protein
HBCGBFBE_01638	2.64e-49	-	-	-	-	-	-	-	-
HBCGBFBE_01639	9.06e-173	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HBCGBFBE_01640	8.69e-190	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HBCGBFBE_01641	5.25e-149	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HBCGBFBE_01642	1.61e-291	-	-	-	P	-	-	-	Chloride transporter, ClC family
HBCGBFBE_01643	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
HBCGBFBE_01644	5.65e-143	-	-	-	I	-	-	-	Acid phosphatase homologues
HBCGBFBE_01646	3.74e-213	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HBCGBFBE_01647	4.9e-202	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
HBCGBFBE_01648	1.62e-242	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HBCGBFBE_01649	2.38e-164	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HBCGBFBE_01650	4.29e-175	XK27_05695	-	-	V	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HBCGBFBE_01651	2.5e-232	kinG	-	-	T	-	-	-	Histidine kinase-like ATPases
HBCGBFBE_01652	5.06e-160	XK27_10500	-	-	K	-	-	-	response regulator
HBCGBFBE_01653	7.23e-202	yvgN	-	-	S	-	-	-	Aldo keto reductase
HBCGBFBE_01654	9.74e-176	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HBCGBFBE_01655	4.74e-107	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HBCGBFBE_01656	1.24e-65	-	-	-	-	-	-	-	-
HBCGBFBE_01657	7.58e-270	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HBCGBFBE_01658	4.85e-167	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HBCGBFBE_01659	4.09e-200	hlyD3	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HBCGBFBE_01660	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HBCGBFBE_01661	3.39e-186	-	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HBCGBFBE_01662	2.41e-189	-	-	-	E	-	-	-	Glyoxalase-like domain
HBCGBFBE_01663	6.23e-288	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
HBCGBFBE_01664	1.1e-125	-	-	-	S	-	-	-	reductase
HBCGBFBE_01665	1.54e-234	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
HBCGBFBE_01666	4.8e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HBCGBFBE_01667	2.08e-215	-	-	-	-	-	-	-	-
HBCGBFBE_01669	1.24e-76	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HBCGBFBE_01670	9.38e-256	-	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
HBCGBFBE_01671	6.63e-202	-	-	-	K	-	-	-	LysR substrate binding domain
HBCGBFBE_01672	2.19e-97	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HBCGBFBE_01673	3.7e-123	-	-	-	K	-	-	-	acetyltransferase
HBCGBFBE_01674	1.15e-204	-	-	-	-	-	-	-	-
HBCGBFBE_01676	1.09e-226	ydhF	-	-	S	-	-	-	Aldo keto reductase
HBCGBFBE_01677	4.51e-101	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	PAP2 superfamily
HBCGBFBE_01678	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
HBCGBFBE_01680	0.0	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
HBCGBFBE_01681	2.84e-73	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
HBCGBFBE_01682	7.41e-163	-	-	-	-	-	-	-	-
HBCGBFBE_01683	4.58e-162	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
HBCGBFBE_01684	1.08e-112	-	-	-	T	-	-	-	EAL domain
HBCGBFBE_01685	0.0	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
HBCGBFBE_01686	7.01e-109	-	-	-	-	-	-	-	-
HBCGBFBE_01687	1.13e-259	-	2.7.7.65	-	T	ko:K02488	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko00002,ko01000,ko02022	GGDEF domain
HBCGBFBE_01688	6.11e-158	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HBCGBFBE_01689	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HBCGBFBE_01690	1.43e-252	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
HBCGBFBE_01691	5.35e-121	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HBCGBFBE_01692	2.61e-51	sugE	-	-	U	ko:K11741	-	ko00000,ko02000	Multidrug resistance protein
HBCGBFBE_01693	5.78e-28	-	-	-	-	-	-	-	-
HBCGBFBE_01697	6.01e-88	ermA	2.1.1.184	-	J	ko:K00561	-	br01600,ko00000,ko01000,ko01504,ko03009	Ribosomal RNA adenine dimethylase
HBCGBFBE_01698	1.31e-103	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
HBCGBFBE_01699	2.02e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HBCGBFBE_01700	1.34e-155	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HBCGBFBE_01701	2.41e-264	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HBCGBFBE_01702	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HBCGBFBE_01703	1.4e-147	yjbH	-	-	Q	-	-	-	Thioredoxin
HBCGBFBE_01704	7.45e-150	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HBCGBFBE_01705	7.22e-197	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HBCGBFBE_01706	1.13e-220	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HBCGBFBE_01707	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HBCGBFBE_01708	1.34e-232	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
HBCGBFBE_01709	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HBCGBFBE_01711	8.9e-131	-	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
HBCGBFBE_01712	7.37e-275	-	1.5.1.36	-	S	ko:K19784,ko:K22393,ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
HBCGBFBE_01713	3.98e-229	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HBCGBFBE_01714	7.06e-164	-	-	-	M	-	-	-	PFAM NLP P60 protein
HBCGBFBE_01715	3.16e-233	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HBCGBFBE_01716	5.58e-195	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HBCGBFBE_01717	5.63e-177	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HBCGBFBE_01718	5.53e-119	-	-	-	P	-	-	-	Cadmium resistance transporter
HBCGBFBE_01719	1.14e-74	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
HBCGBFBE_01723	5.39e-54	-	-	-	M	-	-	-	KxYKxGKxW signal domain protein
HBCGBFBE_01724	1.74e-153	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NLP P60 protein
HBCGBFBE_01725	9.93e-40	-	-	-	-	-	-	-	-
HBCGBFBE_01726	4.98e-160	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HBCGBFBE_01727	2.41e-148	-	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
HBCGBFBE_01728	0.0	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
HBCGBFBE_01729	3.34e-215	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HBCGBFBE_01730	5.27e-97	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HBCGBFBE_01732	2.43e-89	-	-	-	C	-	-	-	lyase activity
HBCGBFBE_01733	1.36e-95	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
HBCGBFBE_01734	1.2e-148	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
HBCGBFBE_01735	3.46e-208	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HBCGBFBE_01736	1.01e-28	-	-	-	-	-	-	-	-
HBCGBFBE_01737	8e-117	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
HBCGBFBE_01738	4.68e-197	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HBCGBFBE_01739	2.54e-60	yrvD	-	-	S	-	-	-	Pfam:DUF1049
HBCGBFBE_01741	1.47e-41	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
HBCGBFBE_01742	2.6e-27	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HBCGBFBE_01743	7.05e-101	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HBCGBFBE_01744	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
HBCGBFBE_01745	7.17e-146	-	-	-	GM	-	-	-	NAD dependent epimerase dehydratase family protein
HBCGBFBE_01746	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
HBCGBFBE_01747	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HBCGBFBE_01748	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
HBCGBFBE_01749	1.89e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
HBCGBFBE_01750	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HBCGBFBE_01751	1.58e-106	-	-	-	-	-	-	-	-
HBCGBFBE_01752	0.0	-	2.4.1.5	GH13	G	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	Glycosyl hydrolase family 70
HBCGBFBE_01753	1.16e-154	p75	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
HBCGBFBE_01754	2.5e-171	-	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C-terminal domain protein
HBCGBFBE_01755	3.3e-203	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HBCGBFBE_01756	1.31e-193	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HBCGBFBE_01757	1.74e-195	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
HBCGBFBE_01758	7.41e-176	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HBCGBFBE_01759	3.52e-161	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HBCGBFBE_01760	2.05e-156	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
HBCGBFBE_01761	1.66e-303	-	-	-	T	-	-	-	GHKL domain
HBCGBFBE_01762	2.28e-139	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HBCGBFBE_01763	1.2e-91	-	-	-	P	-	-	-	FAD-binding domain
HBCGBFBE_01764	1.99e-204	-	-	-	J	-	-	-	Methyltransferase
HBCGBFBE_01765	7.6e-28	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HBCGBFBE_01766	8.19e-219	-	-	-	S	-	-	-	PglZ domain
HBCGBFBE_01767	5.75e-65	doc	-	-	S	ko:K07341	-	ko00000,ko02048	Fic/DOC family
HBCGBFBE_01769	1.61e-252	-	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HBCGBFBE_01770	1.44e-163	-	-	-	O	-	-	-	Zinc-dependent metalloprotease
HBCGBFBE_01771	9.38e-115	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HBCGBFBE_01772	4.16e-200	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HBCGBFBE_01779	4e-109	-	-	-	M	-	-	-	biosynthesis protein
HBCGBFBE_01780	6.08e-235	cps3F	-	-	-	-	-	-	-
HBCGBFBE_01781	5.13e-126	-	-	-	S	-	-	-	enterobacterial common antigen metabolic process
HBCGBFBE_01783	2.64e-87	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NLP P60 protein
HBCGBFBE_01784	4.89e-271	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HBCGBFBE_01785	1.56e-102	pncA	-	-	Q	-	-	-	Isochorismatase family
HBCGBFBE_01787	3.61e-53	yju3	-	-	I	-	-	-	Serine aminopeptidase, S33
HBCGBFBE_01788	1.4e-34	-	-	-	K	-	-	-	TRANSCRIPTIONal
HBCGBFBE_01789	2.67e-57	-	-	-	K	-	-	-	UTRA
HBCGBFBE_01790	1.74e-210	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
HBCGBFBE_01791	7.41e-161	-	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
HBCGBFBE_01792	5.74e-128	-	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
HBCGBFBE_01793	6.07e-150	-	-	-	G	-	-	-	Belongs to the carbohydrate kinase PfkB family
HBCGBFBE_01795	7.69e-13	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HBCGBFBE_01797	8.07e-53	-	-	-	D	-	-	-	nuclear chromosome segregation
HBCGBFBE_01798	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
HBCGBFBE_01799	1.35e-46	-	-	-	C	-	-	-	Heavy-metal-associated domain
HBCGBFBE_01800	1.01e-120	dpsB	-	-	P	-	-	-	Belongs to the Dps family
HBCGBFBE_01801	9.73e-146	fnr	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
HBCGBFBE_01802	4.64e-46	-	-	-	S	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	dextransucrase activity
HBCGBFBE_01803	9.78e-228	yueF	-	-	S	-	-	-	AI-2E family transporter
HBCGBFBE_01804	7.59e-200	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HBCGBFBE_01805	1.76e-264	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HBCGBFBE_01806	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HBCGBFBE_01807	1.87e-218	-	3.2.1.23, 3.2.1.89	-	G	ko:K01190,ko:K01224	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	arabinogalactan endo-1,4-beta-galactosidase activity
HBCGBFBE_01808	0.0	ganB	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
HBCGBFBE_01809	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HBCGBFBE_01811	4.48e-90	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HBCGBFBE_01812	3.35e-59	-	-	-	S	-	-	-	Pfam:DUF59
HBCGBFBE_01813	4.01e-216	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HBCGBFBE_01814	7.12e-171	-	-	-	O	-	-	-	Bacterial dnaA protein
HBCGBFBE_01815	1.51e-300	-	-	-	L	-	-	-	Integrase core domain
HBCGBFBE_01816	0.0	-	-	-	O	-	-	-	Arylsulfotransferase (ASST)
HBCGBFBE_01817	1.19e-84	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
HBCGBFBE_01818	1.69e-197	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HBCGBFBE_01819	2.63e-144	-	-	-	-	-	-	-	-
HBCGBFBE_01820	2.01e-76	-	-	-	-	-	-	-	-
HBCGBFBE_01821	4.83e-215	-	-	-	M	-	-	-	domain protein
HBCGBFBE_01822	6.05e-24	-	-	-	S	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	dextransucrase activity
HBCGBFBE_01823	4.82e-116	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
HBCGBFBE_01824	6.32e-275	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HBCGBFBE_01825	8.37e-185	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
HBCGBFBE_01826	3.09e-104	-	-	-	L	ko:K07483,ko:K07497	-	ko00000	Helix-turn-helix domain
HBCGBFBE_01827	1.08e-293	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HBCGBFBE_01828	6.59e-48	-	-	-	-	-	-	-	-
HBCGBFBE_01829	4.08e-132	-	-	-	K	-	-	-	DNA-templated transcription, initiation
HBCGBFBE_01830	2.08e-39	-	-	-	-	-	-	-	-
HBCGBFBE_01831	6.98e-137	-	-	-	L	-	-	-	Helix-turn-helix domain
HBCGBFBE_01832	5.21e-191	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HBCGBFBE_01833	3.55e-147	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
HBCGBFBE_01834	6.14e-71	-	-	-	-	-	-	-	-
HBCGBFBE_01835	3e-93	-	-	-	-	-	-	-	-
HBCGBFBE_01847	1.08e-05	-	-	-	L	-	-	-	Helix-turn-helix domain
HBCGBFBE_01854	1.15e-101	-	-	-	O	-	-	-	Bacterial dnaA protein
HBCGBFBE_01855	7.99e-124	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HBCGBFBE_01856	2.19e-63	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein