ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
CGEHFNKO_00001 2.14e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
CGEHFNKO_00002 1.33e-82 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
CGEHFNKO_00003 1.63e-258 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
CGEHFNKO_00004 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
CGEHFNKO_00005 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CGEHFNKO_00006 3.12e-250 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
CGEHFNKO_00007 8.6e-251 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
CGEHFNKO_00008 1.23e-160 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
CGEHFNKO_00009 3.02e-111 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
CGEHFNKO_00010 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CGEHFNKO_00011 3.16e-151 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
CGEHFNKO_00012 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
CGEHFNKO_00013 4.11e-95 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CGEHFNKO_00014 4.11e-172 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CGEHFNKO_00015 4.03e-115 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
CGEHFNKO_00016 1.39e-150 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
CGEHFNKO_00017 3.77e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
CGEHFNKO_00018 1.28e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
CGEHFNKO_00019 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CGEHFNKO_00020 8.66e-161 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
CGEHFNKO_00021 2.33e-103 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CGEHFNKO_00022 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
CGEHFNKO_00023 7.25e-140 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
CGEHFNKO_00024 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CGEHFNKO_00025 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CGEHFNKO_00026 9.87e-45 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
CGEHFNKO_00027 9.47e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CGEHFNKO_00028 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
CGEHFNKO_00029 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CGEHFNKO_00030 2.35e-286 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CGEHFNKO_00031 4.91e-241 ybaC - - S - - - Alpha/beta hydrolase family
CGEHFNKO_00032 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
CGEHFNKO_00033 1.77e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CGEHFNKO_00034 3.68e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
CGEHFNKO_00035 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
CGEHFNKO_00036 9.5e-201 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CGEHFNKO_00037 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CGEHFNKO_00038 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CGEHFNKO_00039 1.69e-151 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CGEHFNKO_00040 1.38e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CGEHFNKO_00041 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
CGEHFNKO_00042 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CGEHFNKO_00043 2.55e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CGEHFNKO_00044 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CGEHFNKO_00045 5.43e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CGEHFNKO_00046 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CGEHFNKO_00047 1.08e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CGEHFNKO_00048 3.14e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CGEHFNKO_00049 8.29e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CGEHFNKO_00050 4.54e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CGEHFNKO_00051 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
CGEHFNKO_00052 5.15e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
CGEHFNKO_00053 1.34e-296 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
CGEHFNKO_00054 1.77e-157 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
CGEHFNKO_00055 2.32e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
CGEHFNKO_00056 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CGEHFNKO_00057 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
CGEHFNKO_00058 1.54e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CGEHFNKO_00059 2.28e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CGEHFNKO_00060 4.94e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CGEHFNKO_00061 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
CGEHFNKO_00062 3.05e-199 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CGEHFNKO_00063 4.91e-190 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CGEHFNKO_00064 2.77e-178 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CGEHFNKO_00065 8.74e-182 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
CGEHFNKO_00066 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CGEHFNKO_00067 1.49e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
CGEHFNKO_00068 1.76e-185 ybaJ - - Q - - - Methyltransferase domain
CGEHFNKO_00069 1.97e-103 yizA - - S - - - Damage-inducible protein DinB
CGEHFNKO_00070 1.31e-102 ybaK - - S - - - Protein of unknown function (DUF2521)
CGEHFNKO_00071 1.98e-173 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
CGEHFNKO_00072 9e-254 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
CGEHFNKO_00073 1.95e-102 gerD - - - ko:K06294 - ko00000 -
CGEHFNKO_00074 1.25e-134 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
CGEHFNKO_00075 6.38e-183 pdaB - - G - - - Polysaccharide deacetylase
CGEHFNKO_00077 4.67e-279 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
CGEHFNKO_00078 3.37e-272 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
CGEHFNKO_00079 4.99e-164 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
CGEHFNKO_00080 1.64e-119 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
CGEHFNKO_00081 8.64e-97 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CGEHFNKO_00082 4.32e-48 - - - K - - - SpoVT / AbrB like domain
CGEHFNKO_00083 2.48e-171 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
CGEHFNKO_00084 7.6e-159 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
CGEHFNKO_00085 4.16e-181 blm 3.5.2.6 - S ko:K17837 ko01501,map01501 ko00000,ko00001,ko01000 Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
CGEHFNKO_00086 2.9e-47 - - - - - - - -
CGEHFNKO_00087 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
CGEHFNKO_00088 2.57e-51 spoVIF - - S - - - Stage VI sporulation protein F
CGEHFNKO_00089 5.69e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
CGEHFNKO_00092 2.05e-73 yjcA - - S - - - Protein of unknown function (DUF1360)
CGEHFNKO_00093 2.38e-71 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
CGEHFNKO_00094 8.38e-36 cotW - - - ko:K06341 - ko00000 -
CGEHFNKO_00095 3.71e-100 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
CGEHFNKO_00096 1.61e-116 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
CGEHFNKO_00097 1.12e-103 cotZ - - S ko:K06344 - ko00000 Spore coat protein
CGEHFNKO_00098 2.9e-126 yjbX - - S - - - Spore coat protein
CGEHFNKO_00099 6.85e-180 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
CGEHFNKO_00100 7.44e-190 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
CGEHFNKO_00101 1.11e-240 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
CGEHFNKO_00102 3.65e-173 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
CGEHFNKO_00103 3.73e-40 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 Thiamine biosynthesis
CGEHFNKO_00104 3.22e-268 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
CGEHFNKO_00105 2.32e-138 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
CGEHFNKO_00106 2.71e-177 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CGEHFNKO_00107 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
CGEHFNKO_00108 5.27e-184 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
CGEHFNKO_00109 1.42e-212 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
CGEHFNKO_00110 2.07e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CGEHFNKO_00111 1.56e-139 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
CGEHFNKO_00112 2.03e-80 yjbL - - S - - - Belongs to the UPF0738 family
CGEHFNKO_00113 1.21e-128 yjbK - - S - - - protein conserved in bacteria
CGEHFNKO_00114 7.66e-153 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
CGEHFNKO_00115 1.22e-93 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
CGEHFNKO_00116 2.46e-219 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
CGEHFNKO_00117 3.14e-27 - - - - - - - -
CGEHFNKO_00118 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
CGEHFNKO_00119 4.01e-282 coiA - - S ko:K06198 - ko00000 Competence protein
CGEHFNKO_00120 9.78e-150 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
CGEHFNKO_00121 2.77e-141 yjbE - - P - - - Integral membrane protein TerC family
CGEHFNKO_00122 2.47e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
CGEHFNKO_00123 4.4e-132 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CGEHFNKO_00124 7.07e-295 - - - S - - - Putative glycosyl hydrolase domain
CGEHFNKO_00125 1.27e-219 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
CGEHFNKO_00126 1.5e-256 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
CGEHFNKO_00127 3.59e-210 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CGEHFNKO_00128 2.53e-213 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CGEHFNKO_00129 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
CGEHFNKO_00130 4.15e-233 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
CGEHFNKO_00131 5.28e-189 yjbA - - S - - - Belongs to the UPF0736 family
CGEHFNKO_00132 7.81e-209 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CGEHFNKO_00133 4.24e-219 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CGEHFNKO_00134 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
CGEHFNKO_00135 7.23e-238 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
CGEHFNKO_00136 7.17e-233 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
CGEHFNKO_00137 7.48e-190 yjaZ - - O - - - Zn-dependent protease
CGEHFNKO_00138 3.7e-298 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
CGEHFNKO_00139 3.78e-220 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CGEHFNKO_00140 2.82e-44 yjzB - - - - - - -
CGEHFNKO_00141 6.46e-37 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
CGEHFNKO_00142 2.7e-212 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
CGEHFNKO_00143 5.83e-135 yjaV - - - - - - -
CGEHFNKO_00144 1.57e-178 yjaU - - I - - - carboxylic ester hydrolase activity
CGEHFNKO_00145 1.06e-32 yjzD - - S - - - Protein of unknown function (DUF2929)
CGEHFNKO_00146 7.21e-39 yjzC - - S - - - YjzC-like protein
CGEHFNKO_00147 4.46e-42 csfB - - S - - - Inhibitor of sigma-G Gin
CGEHFNKO_00148 7.19e-137 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
CGEHFNKO_00149 6.94e-244 yaaN - - P - - - Belongs to the TelA family
CGEHFNKO_00150 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
CGEHFNKO_00151 7.75e-145 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CGEHFNKO_00152 5.03e-73 yaaQ - - S - - - protein conserved in bacteria
CGEHFNKO_00153 2.98e-94 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
CGEHFNKO_00154 2.82e-235 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
CGEHFNKO_00155 9e-189 yaaT - - S - - - stage 0 sporulation protein
CGEHFNKO_00156 3.08e-56 yabA - - L - - - Involved in initiation control of chromosome replication
CGEHFNKO_00157 3.99e-178 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
CGEHFNKO_00158 6.96e-64 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
CGEHFNKO_00159 4.93e-211 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CGEHFNKO_00160 6.14e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
CGEHFNKO_00161 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CGEHFNKO_00162 2.49e-183 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
CGEHFNKO_00163 1.53e-304 yabE - - T - - - protein conserved in bacteria
CGEHFNKO_00164 7.62e-126 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CGEHFNKO_00165 2.07e-203 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
CGEHFNKO_00166 1.41e-209 yabG - - S ko:K06436 - ko00000 peptidase
CGEHFNKO_00167 5.32e-53 veg - - S - - - protein conserved in bacteria
CGEHFNKO_00168 7.31e-38 sspF - - S ko:K06423 - ko00000 DNA topological change
CGEHFNKO_00169 2.73e-206 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CGEHFNKO_00170 5.67e-197 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
CGEHFNKO_00171 7.5e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
CGEHFNKO_00172 4.23e-64 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
CGEHFNKO_00173 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CGEHFNKO_00174 2.47e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CGEHFNKO_00175 3.72e-138 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CGEHFNKO_00176 1.18e-134 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
CGEHFNKO_00177 1.1e-54 yabK - - S - - - Peptide ABC transporter permease
CGEHFNKO_00178 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CGEHFNKO_00179 8.02e-119 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
CGEHFNKO_00180 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CGEHFNKO_00181 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
CGEHFNKO_00182 8.51e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
CGEHFNKO_00183 5.47e-66 yabP - - S - - - Sporulation protein YabP
CGEHFNKO_00184 9.66e-134 yabQ - - S - - - spore cortex biosynthesis protein
CGEHFNKO_00185 1.2e-74 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
CGEHFNKO_00186 3.54e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
CGEHFNKO_00189 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
CGEHFNKO_00190 3.79e-166 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
CGEHFNKO_00191 5.47e-235 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
CGEHFNKO_00192 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
CGEHFNKO_00193 1.05e-119 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
CGEHFNKO_00194 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CGEHFNKO_00195 9.51e-177 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CGEHFNKO_00196 3.19e-206 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CGEHFNKO_00197 7.16e-201 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
CGEHFNKO_00198 8.88e-217 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
CGEHFNKO_00199 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CGEHFNKO_00200 1.87e-139 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
CGEHFNKO_00201 1.64e-205 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
CGEHFNKO_00202 2.24e-203 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CGEHFNKO_00203 1.13e-81 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CGEHFNKO_00204 8.2e-118 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CGEHFNKO_00205 1.01e-38 yazB - - K - - - transcriptional
CGEHFNKO_00206 5.32e-242 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CGEHFNKO_00207 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
CGEHFNKO_00229 9.03e-103 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
CGEHFNKO_00230 1.28e-170 yteA - - T - - - COG1734 DnaK suppressor protein
CGEHFNKO_00231 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
CGEHFNKO_00232 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CGEHFNKO_00233 8.79e-200 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
CGEHFNKO_00234 7.52e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CGEHFNKO_00235 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
CGEHFNKO_00236 1.43e-272 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
CGEHFNKO_00237 1.92e-34 - - - S - - - Domain of Unknown Function (DUF1540)
CGEHFNKO_00238 2.6e-235 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
CGEHFNKO_00239 1.82e-312 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
CGEHFNKO_00240 8.35e-55 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
CGEHFNKO_00241 9.31e-137 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
CGEHFNKO_00242 6.93e-53 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
CGEHFNKO_00243 7.16e-114 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
CGEHFNKO_00244 3.62e-100 ytkA - - S - - - YtkA-like
CGEHFNKO_00246 1.8e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
CGEHFNKO_00247 1.23e-79 ytkC - - S - - - Bacteriophage holin family
CGEHFNKO_00248 4.13e-114 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
CGEHFNKO_00249 7.52e-174 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
CGEHFNKO_00250 6.12e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
CGEHFNKO_00251 1.3e-238 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
CGEHFNKO_00252 1.35e-190 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
CGEHFNKO_00253 2.85e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
CGEHFNKO_00254 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CGEHFNKO_00255 7.88e-287 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CGEHFNKO_00256 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
CGEHFNKO_00257 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
CGEHFNKO_00258 4.06e-84 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CGEHFNKO_00259 6.95e-194 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
CGEHFNKO_00260 2.02e-271 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
CGEHFNKO_00261 1.05e-184 - 3.1.4.46, 5.4.2.11 - C ko:K01126,ko:K01834 ko00010,ko00260,ko00564,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00564,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 glycerophosphoryl diester phosphodiesterase
CGEHFNKO_00263 3.1e-137 ytqB - - J - - - Putative rRNA methylase
CGEHFNKO_00264 5.76e-245 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
CGEHFNKO_00265 1.43e-52 ytzC - - S - - - Protein of unknown function (DUF2524)
CGEHFNKO_00266 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
CGEHFNKO_00267 4.38e-209 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
CGEHFNKO_00268 1.18e-210 ytrC - - S ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
CGEHFNKO_00269 1.97e-230 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
CGEHFNKO_00270 4.46e-210 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
CGEHFNKO_00271 2.12e-161 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
CGEHFNKO_00272 2.25e-286 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
CGEHFNKO_00273 6.13e-165 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CGEHFNKO_00274 7.45e-223 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
CGEHFNKO_00275 4.63e-174 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
CGEHFNKO_00276 0.0 bceB - - V ko:K02004,ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
CGEHFNKO_00277 3.96e-165 ywaF - - S - - - Integral membrane protein
CGEHFNKO_00278 1.12e-267 yttB - - EGP - - - Major facilitator superfamily
CGEHFNKO_00281 2.07e-235 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CGEHFNKO_00282 9.02e-113 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
CGEHFNKO_00283 1.02e-162 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
CGEHFNKO_00284 1.41e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
CGEHFNKO_00285 1.08e-243 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CGEHFNKO_00286 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
CGEHFNKO_00287 2.95e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
CGEHFNKO_00288 2.6e-149 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CGEHFNKO_00289 1.72e-29 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
CGEHFNKO_00290 5.74e-161 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CGEHFNKO_00291 1.11e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
CGEHFNKO_00292 8.26e-165 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
CGEHFNKO_00293 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CGEHFNKO_00294 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
CGEHFNKO_00295 7.07e-51 - - - S - - - Protein of unknown function (DUF4064)
CGEHFNKO_00296 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
CGEHFNKO_00297 9.75e-255 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
CGEHFNKO_00298 0.0 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
CGEHFNKO_00299 2.86e-219 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
CGEHFNKO_00300 5.98e-40 yjdJ - - S - - - Domain of unknown function (DUF4306)
CGEHFNKO_00301 1.36e-146 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
CGEHFNKO_00302 1.55e-229 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CGEHFNKO_00303 5.51e-163 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
CGEHFNKO_00304 1.31e-222 ydjI - - S - - - virion core protein (lumpy skin disease virus)
CGEHFNKO_00305 0.0 oatA - - I - - - Acyltransferase family
CGEHFNKO_00306 1.68e-194 rsiV - - S - - - Protein of unknown function (DUF3298)
CGEHFNKO_00307 1.87e-113 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
CGEHFNKO_00308 1.74e-249 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
CGEHFNKO_00310 1.35e-37 - - - L - - - Belongs to the 'phage' integrase family
CGEHFNKO_00311 9.37e-41 - - - K - - - Cro/C1-type HTH DNA-binding domain
CGEHFNKO_00312 3.92e-83 ydjM - - M - - - Lytic transglycolase
CGEHFNKO_00313 3.89e-192 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
CGEHFNKO_00314 3.5e-235 yaaC - - S - - - YaaC-like Protein
CGEHFNKO_00315 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
CGEHFNKO_00316 0.0 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
CGEHFNKO_00317 1.29e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CGEHFNKO_00318 4.75e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CGEHFNKO_00319 1.59e-285 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CGEHFNKO_00320 1.14e-258 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
CGEHFNKO_00322 7.51e-159 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
CGEHFNKO_00323 9.51e-148 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
CGEHFNKO_00324 7.12e-278 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
CGEHFNKO_00325 1.75e-129 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
CGEHFNKO_00326 2.48e-111 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
CGEHFNKO_00327 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CGEHFNKO_00328 2.41e-52 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CGEHFNKO_00329 6e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CGEHFNKO_00330 5.4e-43 yaaL - - S - - - Protein of unknown function (DUF2508)
CGEHFNKO_00331 6.2e-48 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
CGEHFNKO_00337 3.48e-63 ylaE - - - - - - -
CGEHFNKO_00338 5.62e-33 - - - S - - - Family of unknown function (DUF5325)
CGEHFNKO_00339 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
CGEHFNKO_00340 6.99e-65 - - - S - - - YlaH-like protein
CGEHFNKO_00341 6.78e-46 ylaI - - S - - - protein conserved in bacteria
CGEHFNKO_00342 3.84e-138 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
CGEHFNKO_00343 2.7e-313 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
CGEHFNKO_00344 1.23e-110 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CGEHFNKO_00345 2.67e-223 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
CGEHFNKO_00346 1.99e-58 ylaN - - S - - - Belongs to the UPF0358 family
CGEHFNKO_00347 8.59e-272 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
CGEHFNKO_00348 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CGEHFNKO_00349 1.16e-212 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
CGEHFNKO_00350 2.07e-209 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
CGEHFNKO_00351 3.24e-250 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
CGEHFNKO_00352 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CGEHFNKO_00353 5.92e-142 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
CGEHFNKO_00354 3.53e-69 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
CGEHFNKO_00355 3.59e-212 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
CGEHFNKO_00356 4.12e-79 ylbA - - S - - - YugN-like family
CGEHFNKO_00357 3.35e-96 ylbB - - T - - - COG0517 FOG CBS domain
CGEHFNKO_00358 1.62e-254 ylbC - - S - - - protein with SCP PR1 domains
CGEHFNKO_00359 5.72e-85 ylbD - - S - - - Putative coat protein
CGEHFNKO_00360 1.73e-48 ylbE - - S - - - YlbE-like protein
CGEHFNKO_00361 3.33e-97 ylbF - - S - - - Belongs to the UPF0342 family
CGEHFNKO_00362 2.78e-57 ylbG - - S - - - UPF0298 protein
CGEHFNKO_00363 7.68e-116 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
CGEHFNKO_00364 1.01e-110 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CGEHFNKO_00365 1.02e-277 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
CGEHFNKO_00366 1.23e-178 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
CGEHFNKO_00367 3.07e-240 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
CGEHFNKO_00368 1.56e-296 ylbM - - S - - - Belongs to the UPF0348 family
CGEHFNKO_00369 4.88e-117 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
CGEHFNKO_00370 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
CGEHFNKO_00371 1.16e-106 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
CGEHFNKO_00372 3.26e-116 ylbP - - K - - - n-acetyltransferase
CGEHFNKO_00373 2.39e-210 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CGEHFNKO_00374 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
CGEHFNKO_00375 1.78e-101 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
CGEHFNKO_00376 4.08e-219 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
CGEHFNKO_00377 2.4e-68 ftsL - - D - - - Essential cell division protein
CGEHFNKO_00378 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
CGEHFNKO_00379 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
CGEHFNKO_00380 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CGEHFNKO_00381 7.04e-222 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CGEHFNKO_00382 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CGEHFNKO_00383 2.7e-236 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
CGEHFNKO_00384 5.69e-259 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CGEHFNKO_00385 1.17e-214 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
CGEHFNKO_00386 2.67e-179 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
CGEHFNKO_00387 1.57e-298 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
CGEHFNKO_00388 2.61e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CGEHFNKO_00389 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
CGEHFNKO_00390 2.75e-216 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
CGEHFNKO_00391 7.35e-161 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CGEHFNKO_00392 9.33e-179 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CGEHFNKO_00393 1.14e-186 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
CGEHFNKO_00394 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
CGEHFNKO_00395 7.13e-52 ylmC - - S - - - sporulation protein
CGEHFNKO_00396 2.74e-205 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
CGEHFNKO_00397 9.03e-162 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CGEHFNKO_00398 7.98e-86 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
CGEHFNKO_00399 5.12e-56 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
CGEHFNKO_00400 6.12e-182 ylmH - - S - - - conserved protein, contains S4-like domain
CGEHFNKO_00401 1.85e-99 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
CGEHFNKO_00402 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CGEHFNKO_00403 4.22e-83 ylyA - - T - - - COG1734 DnaK suppressor protein
CGEHFNKO_00404 1.24e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CGEHFNKO_00405 8.87e-215 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
CGEHFNKO_00406 8.98e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CGEHFNKO_00407 2.81e-296 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
CGEHFNKO_00408 5.13e-214 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
CGEHFNKO_00409 1.36e-315 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
CGEHFNKO_00410 3.61e-267 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
CGEHFNKO_00411 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
CGEHFNKO_00412 2.39e-179 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
CGEHFNKO_00413 2.57e-222 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
CGEHFNKO_00414 2.12e-162 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
CGEHFNKO_00415 1.49e-147 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CGEHFNKO_00417 9.88e-181 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
CGEHFNKO_00418 2.01e-227 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
CGEHFNKO_00419 3.72e-285 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
CGEHFNKO_00420 1.94e-142 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
CGEHFNKO_00421 5.66e-183 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
CGEHFNKO_00422 1.97e-185 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
CGEHFNKO_00423 1.21e-103 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
CGEHFNKO_00424 4.69e-172 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
CGEHFNKO_00425 2.87e-57 - - - L - - - transposase activity
CGEHFNKO_00426 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
CGEHFNKO_00427 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
CGEHFNKO_00428 2.14e-198 yloC - - S - - - stress-induced protein
CGEHFNKO_00429 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
CGEHFNKO_00430 4.91e-144 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
CGEHFNKO_00431 2.53e-38 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
CGEHFNKO_00432 2.18e-287 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CGEHFNKO_00433 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CGEHFNKO_00434 5.84e-110 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
CGEHFNKO_00435 4.76e-224 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CGEHFNKO_00436 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CGEHFNKO_00437 1.52e-263 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
CGEHFNKO_00438 3.51e-178 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
CGEHFNKO_00439 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
CGEHFNKO_00440 6.22e-211 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
CGEHFNKO_00441 2.93e-149 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
CGEHFNKO_00442 2.61e-153 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
CGEHFNKO_00443 3.49e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
CGEHFNKO_00444 3.65e-78 yloU - - S - - - protein conserved in bacteria
CGEHFNKO_00445 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
CGEHFNKO_00446 4.15e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
CGEHFNKO_00447 5.64e-200 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
CGEHFNKO_00448 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CGEHFNKO_00449 4.38e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
CGEHFNKO_00450 3.14e-229 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
CGEHFNKO_00451 1.31e-218 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
CGEHFNKO_00452 8.61e-168 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
CGEHFNKO_00453 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
CGEHFNKO_00454 3.02e-174 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
CGEHFNKO_00455 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
CGEHFNKO_00456 1.87e-224 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CGEHFNKO_00457 8.34e-180 - - - S - - - Phosphotransferase enzyme family
CGEHFNKO_00458 1.97e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CGEHFNKO_00459 2.09e-303 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CGEHFNKO_00460 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
CGEHFNKO_00461 1.41e-48 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
CGEHFNKO_00462 3.41e-80 ylqD - - S - - - YlqD protein
CGEHFNKO_00463 6.16e-121 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CGEHFNKO_00464 5.67e-176 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
CGEHFNKO_00465 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
CGEHFNKO_00466 4.19e-202 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CGEHFNKO_00467 1.95e-173 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CGEHFNKO_00468 0.0 ylqG - - - - - - -
CGEHFNKO_00469 4.88e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
CGEHFNKO_00470 2.02e-270 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
CGEHFNKO_00471 7.59e-214 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CGEHFNKO_00472 1.54e-217 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
CGEHFNKO_00473 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CGEHFNKO_00474 3.83e-314 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CGEHFNKO_00475 8.93e-220 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
CGEHFNKO_00476 7.38e-121 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CGEHFNKO_00477 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CGEHFNKO_00478 2.77e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CGEHFNKO_00479 7.04e-69 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
CGEHFNKO_00480 1.07e-98 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
CGEHFNKO_00481 1.51e-50 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
CGEHFNKO_00482 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
CGEHFNKO_00483 2.48e-229 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
CGEHFNKO_00484 2.29e-121 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
CGEHFNKO_00485 1e-306 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
CGEHFNKO_00486 2.17e-92 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
CGEHFNKO_00487 3.43e-89 ylxF - - S - - - MgtE intracellular N domain
CGEHFNKO_00488 3.66e-261 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
CGEHFNKO_00489 1.54e-96 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
CGEHFNKO_00490 2.29e-178 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
CGEHFNKO_00491 7.7e-80 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
CGEHFNKO_00492 5.43e-230 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
CGEHFNKO_00493 7.29e-249 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CGEHFNKO_00494 2.12e-77 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
CGEHFNKO_00495 9.34e-144 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
CGEHFNKO_00496 1.48e-142 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
CGEHFNKO_00497 3.15e-51 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
CGEHFNKO_00498 1.16e-167 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
CGEHFNKO_00499 2.53e-242 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CGEHFNKO_00500 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CGEHFNKO_00501 7.61e-248 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
CGEHFNKO_00502 9.02e-200 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
CGEHFNKO_00503 3.35e-247 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
CGEHFNKO_00504 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
CGEHFNKO_00505 2.49e-105 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
CGEHFNKO_00506 3.99e-141 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
CGEHFNKO_00507 8.2e-113 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
CGEHFNKO_00508 3.26e-176 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CGEHFNKO_00509 3.38e-93 ylxL - - - - - - -
CGEHFNKO_00510 1.74e-167 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
CGEHFNKO_00511 1.63e-200 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CGEHFNKO_00512 7.09e-164 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
CGEHFNKO_00513 1.94e-118 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
CGEHFNKO_00514 7.76e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CGEHFNKO_00515 1.09e-178 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
CGEHFNKO_00516 2.2e-273 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
CGEHFNKO_00517 1.15e-296 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
CGEHFNKO_00518 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
CGEHFNKO_00519 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CGEHFNKO_00520 5.66e-106 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
CGEHFNKO_00521 4.04e-264 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
CGEHFNKO_00522 6.76e-56 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
CGEHFNKO_00523 6.16e-63 ylxQ - - J - - - ribosomal protein
CGEHFNKO_00524 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CGEHFNKO_00525 3.88e-60 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
CGEHFNKO_00526 1.03e-73 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CGEHFNKO_00527 1.48e-220 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CGEHFNKO_00528 2.6e-232 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
CGEHFNKO_00529 4.12e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CGEHFNKO_00530 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
CGEHFNKO_00531 3.56e-233 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
CGEHFNKO_00532 4.85e-298 mlpA - - S - - - Belongs to the peptidase M16 family
CGEHFNKO_00533 2.17e-56 ymxH - - S - - - YlmC YmxH family
CGEHFNKO_00534 3.31e-206 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
CGEHFNKO_00535 4.75e-138 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
CGEHFNKO_00536 4.97e-249 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CGEHFNKO_00537 2e-282 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
CGEHFNKO_00538 7.2e-202 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CGEHFNKO_00539 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CGEHFNKO_00540 1.38e-168 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
CGEHFNKO_00541 8.98e-42 - - - S - - - YlzJ-like protein
CGEHFNKO_00542 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
CGEHFNKO_00543 4.48e-172 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
CGEHFNKO_00544 9.04e-296 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
CGEHFNKO_00545 9.88e-100 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
CGEHFNKO_00546 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
CGEHFNKO_00547 2.65e-305 albE - - S - - - Peptidase M16
CGEHFNKO_00548 5.83e-310 ymfH - - S - - - zinc protease
CGEHFNKO_00549 4.27e-166 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
CGEHFNKO_00550 6.23e-56 ymfJ - - S - - - Protein of unknown function (DUF3243)
CGEHFNKO_00551 3.82e-184 ymfK - - S - - - Protein of unknown function (DUF3388)
CGEHFNKO_00552 1.17e-178 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
CGEHFNKO_00553 1.17e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CGEHFNKO_00554 1.09e-292 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
CGEHFNKO_00555 3.06e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CGEHFNKO_00556 7.76e-279 pbpX - - V - - - Beta-lactamase
CGEHFNKO_00557 2.91e-308 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
CGEHFNKO_00558 3.72e-196 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
CGEHFNKO_00559 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
CGEHFNKO_00560 1.43e-251 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
CGEHFNKO_00561 8.65e-275 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
CGEHFNKO_00562 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CGEHFNKO_00563 2.11e-88 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
CGEHFNKO_00564 7.09e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
CGEHFNKO_00565 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CGEHFNKO_00566 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CGEHFNKO_00569 4.05e-166 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
CGEHFNKO_00570 3.33e-207 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
CGEHFNKO_00571 5.25e-233 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
CGEHFNKO_00572 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
CGEHFNKO_00573 3.05e-48 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
CGEHFNKO_00574 3.63e-309 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
CGEHFNKO_00575 1.24e-186 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
CGEHFNKO_00576 3.99e-179 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
CGEHFNKO_00577 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
CGEHFNKO_00578 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
CGEHFNKO_00579 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
CGEHFNKO_00580 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
CGEHFNKO_00581 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
CGEHFNKO_00582 9.7e-294 cypA 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
CGEHFNKO_00583 4.27e-102 nucB - - M - - - Deoxyribonuclease NucA/NucB
CGEHFNKO_00584 1.28e-152 yoaK - - S - - - Membrane
CGEHFNKO_00585 2.78e-82 ymzB - - - - - - -
CGEHFNKO_00586 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
CGEHFNKO_00587 3.03e-06 - - - - - - - -
CGEHFNKO_00588 1.18e-164 ymaC - - S - - - Replication protein
CGEHFNKO_00589 1.41e-103 ymaD - - O - - - redox protein, regulator of disulfide bond formation
CGEHFNKO_00590 7.46e-72 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
CGEHFNKO_00591 1.82e-63 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
CGEHFNKO_00593 5.96e-77 ymaF - - S - - - YmaF family
CGEHFNKO_00594 2.19e-220 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CGEHFNKO_00595 9e-46 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
CGEHFNKO_00596 4.76e-56 - - - - - - - -
CGEHFNKO_00597 9.42e-29 ymzA - - - - - - -
CGEHFNKO_00598 1.61e-88 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
CGEHFNKO_00599 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CGEHFNKO_00600 5.77e-244 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CGEHFNKO_00601 1.11e-141 ymaB - - S - - - MutT family
CGEHFNKO_00602 3.1e-05 - - - M - - - Ami_2
CGEHFNKO_00603 1.78e-122 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
CGEHFNKO_00604 1.55e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
CGEHFNKO_00605 1.56e-294 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CGEHFNKO_00606 5.82e-311 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
CGEHFNKO_00607 4.39e-88 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
CGEHFNKO_00608 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
CGEHFNKO_00609 5.57e-271 mrjp - - G - - - Major royal jelly protein
CGEHFNKO_00610 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
CGEHFNKO_00611 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
CGEHFNKO_00612 9.04e-278 xylR - - GK - - - ROK family
CGEHFNKO_00613 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
CGEHFNKO_00614 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
CGEHFNKO_00615 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
CGEHFNKO_00618 2.21e-27 - - - - - - - -
CGEHFNKO_00619 4.88e-72 dinB - - S - - - DinB family
CGEHFNKO_00620 1.7e-236 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
CGEHFNKO_00622 8.73e-185 yoaP - - K - - - YoaP-like
CGEHFNKO_00623 2.02e-122 - - - J - - - Acetyltransferase (GNAT) domain
CGEHFNKO_00624 5.35e-55 - - - - - - - -
CGEHFNKO_00626 2.09e-140 - - - S - - - Domain of unknown function (DUF3885)
CGEHFNKO_00627 1.19e-257 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CGEHFNKO_00628 1.65e-152 - - AA10,CBM73 S ko:K03933 - ko00000 Pfam:Chitin_bind_3
CGEHFNKO_00629 9.28e-07 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
CGEHFNKO_00630 2.14e-123 yvgO - - - - - - -
CGEHFNKO_00632 0.0 yobO - - M - - - Pectate lyase superfamily protein
CGEHFNKO_00633 1.49e-102 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
CGEHFNKO_00634 5.2e-187 yndL - - S - - - Replication protein
CGEHFNKO_00635 1.74e-11 - - - - - - - -
CGEHFNKO_00636 6.29e-185 - - - O - - - COG0330 Membrane protease subunits, stomatin prohibitin homologs
CGEHFNKO_00637 1.3e-94 yndM - - S - - - Protein of unknown function (DUF2512)
CGEHFNKO_00639 7.8e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CGEHFNKO_00640 1.01e-67 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
CGEHFNKO_00641 3.02e-144 yneB - - L - - - resolvase
CGEHFNKO_00642 2.33e-43 ynzC - - S - - - UPF0291 protein
CGEHFNKO_00643 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CGEHFNKO_00644 1.08e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
CGEHFNKO_00645 6.2e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
CGEHFNKO_00646 1.97e-33 ynzD - - S - - - Spo0E like sporulation regulatory protein
CGEHFNKO_00647 4.47e-164 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
CGEHFNKO_00648 7.09e-76 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
CGEHFNKO_00649 2.27e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
CGEHFNKO_00650 1.18e-98 yneK - - S - - - Protein of unknown function (DUF2621)
CGEHFNKO_00651 7.01e-82 cotM - - O ko:K06335 - ko00000 Spore coat protein
CGEHFNKO_00652 1.97e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
CGEHFNKO_00653 6.2e-22 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
CGEHFNKO_00654 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CGEHFNKO_00655 2.01e-119 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CGEHFNKO_00657 1.48e-45 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
CGEHFNKO_00658 2.94e-97 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
CGEHFNKO_00659 1.34e-70 yneQ - - - - - - -
CGEHFNKO_00660 2.67e-66 yneR - - S - - - Belongs to the HesB IscA family
CGEHFNKO_00661 1.29e-120 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
CGEHFNKO_00662 9.94e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
CGEHFNKO_00663 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CGEHFNKO_00664 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CGEHFNKO_00665 2.21e-19 - - - - - - - -
CGEHFNKO_00666 1.82e-63 ynfC - - - - - - -
CGEHFNKO_00667 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
CGEHFNKO_00668 7.44e-230 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
CGEHFNKO_00669 1.28e-233 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
CGEHFNKO_00670 1.84e-147 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
CGEHFNKO_00671 1.09e-268 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
CGEHFNKO_00672 7.14e-192 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
CGEHFNKO_00673 7.45e-233 regR - - K ko:K02525 - ko00000,ko03000 transcriptional
CGEHFNKO_00674 1.59e-286 exuT - - G ko:K08191,ko:K08194 - ko00000,ko02000 Sugar (and other) transporter
CGEHFNKO_00675 1.41e-201 yndG - - S - - - DoxX-like family
CGEHFNKO_00676 1.57e-99 - - - S - - - Domain of unknown function (DUF4166)
CGEHFNKO_00677 0.0 yndJ - - S - - - YndJ-like protein
CGEHFNKO_00678 7.65e-32 yxlH - - EGP - - - Major Facilitator Superfamily
CGEHFNKO_00681 2.99e-34 - - - - - - - -
CGEHFNKO_00683 1.85e-173 - - - S - - - COG0457 FOG TPR repeat
CGEHFNKO_00687 2.51e-64 - - - S ko:K02004 - ko00000,ko00002,ko02000 Protein of unknown function (DUF1430)
CGEHFNKO_00689 1.16e-81 - - - V ko:K02003,ko:K09810 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
CGEHFNKO_00691 1.15e-276 - - - S - - - Platelet-activating factor acetylhydrolase, isoform II
CGEHFNKO_00692 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
CGEHFNKO_00693 3.64e-70 yvlA - - S - - - Domain of unknown function (DUF4870)
CGEHFNKO_00694 5.07e-314 - - - T - - - Histidine kinase
CGEHFNKO_00695 6.55e-165 - - - T - - - Transcriptional regulatory protein, C terminal
CGEHFNKO_00696 1.97e-316 ynfF 3.2.1.136 GH5 G ko:K15924 - ko00000,ko01000 Glycosyl hydrolase family 30 beta sandwich domain
CGEHFNKO_00697 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
CGEHFNKO_00698 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CGEHFNKO_00699 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CGEHFNKO_00700 0.0 nrsA - - Q ko:K15661 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CGEHFNKO_00701 4.37e-284 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
CGEHFNKO_00702 5.83e-178 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
CGEHFNKO_00703 1.29e-156 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
CGEHFNKO_00704 1.27e-161 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CGEHFNKO_00705 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
CGEHFNKO_00706 2.25e-285 bioI 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
CGEHFNKO_00707 1.94e-247 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CGEHFNKO_00708 1.83e-167 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CGEHFNKO_00709 4.12e-275 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
CGEHFNKO_00710 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
CGEHFNKO_00711 1.63e-186 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
CGEHFNKO_00712 9.19e-95 yngA - - S - - - membrane
CGEHFNKO_00713 4.35e-207 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
CGEHFNKO_00714 5.33e-135 yngC - - S - - - SNARE associated Golgi protein
CGEHFNKO_00715 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
CGEHFNKO_00716 1.18e-176 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
CGEHFNKO_00717 1.48e-215 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
CGEHFNKO_00718 2.77e-41 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
CGEHFNKO_00719 0.0 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
CGEHFNKO_00720 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
CGEHFNKO_00721 5.35e-268 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
CGEHFNKO_00722 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
CGEHFNKO_00723 1.67e-85 yngL - - S - - - Protein of unknown function (DUF1360)
CGEHFNKO_00724 0.0 - - - Q ko:K15656,ko:K15668 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 D-alanine [D-alanyl carrier protein] ligase activity
CGEHFNKO_00725 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CGEHFNKO_00726 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CGEHFNKO_00727 0.0 - - - Q ko:K15665 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CGEHFNKO_00728 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CGEHFNKO_00729 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
CGEHFNKO_00730 2.85e-241 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
CGEHFNKO_00731 2.49e-310 yoeA - - V - - - MATE efflux family protein
CGEHFNKO_00732 1.5e-124 yoeB - - S - - - IseA DL-endopeptidase inhibitor
CGEHFNKO_00734 3.97e-125 - - - L - - - Integrase
CGEHFNKO_00735 6.69e-47 yoeD - - G - - - Helix-turn-helix domain
CGEHFNKO_00736 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
CGEHFNKO_00737 5.59e-255 - - - EGP ko:K08164 - ko00000,ko02000 -transporter
CGEHFNKO_00738 3.29e-67 - - - K - - - Helix-turn-helix domain
CGEHFNKO_00739 5.22e-18 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CGEHFNKO_00740 1.91e-201 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
CGEHFNKO_00741 4.88e-237 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
CGEHFNKO_00742 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
CGEHFNKO_00743 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
CGEHFNKO_00744 3.04e-204 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
CGEHFNKO_00745 3.43e-260 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CGEHFNKO_00746 6.89e-181 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CGEHFNKO_00747 3.87e-80 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
CGEHFNKO_00748 1.73e-160 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
CGEHFNKO_00749 1.45e-57 - - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CGEHFNKO_00750 1.9e-179 yoxB - - - - - - -
CGEHFNKO_00751 7.72e-262 yoaB - - EGP - - - the major facilitator superfamily
CGEHFNKO_00752 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
CGEHFNKO_00753 2.98e-246 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CGEHFNKO_00754 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CGEHFNKO_00755 2.1e-34 yoaF - - - - - - -
CGEHFNKO_00757 1.63e-128 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
CGEHFNKO_00758 2.33e-57 - - - - - - - -
CGEHFNKO_00759 1.25e-107 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
CGEHFNKO_00760 1.81e-277 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
CGEHFNKO_00761 2.39e-89 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
CGEHFNKO_00762 3.02e-70 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
CGEHFNKO_00763 1.06e-172 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
CGEHFNKO_00764 4.57e-123 yobS - - K - - - Transcriptional regulator
CGEHFNKO_00765 4.67e-173 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
CGEHFNKO_00766 3.86e-119 yobW - - - - - - -
CGEHFNKO_00767 7.69e-73 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
CGEHFNKO_00768 1.19e-157 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
CGEHFNKO_00769 2.69e-117 yozB - - S ko:K08976 - ko00000 membrane
CGEHFNKO_00770 1.95e-178 - - - J - - - Protein required for attachment to host cells
CGEHFNKO_00771 1.6e-123 yocC - - - - - - -
CGEHFNKO_00772 2.34e-241 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
CGEHFNKO_00774 3.79e-163 yocH - - M - - - COG1388 FOG LysM repeat
CGEHFNKO_00775 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
CGEHFNKO_00776 2.32e-144 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CGEHFNKO_00778 1.29e-78 yocK - - T - - - general stress protein
CGEHFNKO_00779 3.83e-13 yocL - - - - - - -
CGEHFNKO_00780 3.51e-13 yocN - - - - - - -
CGEHFNKO_00781 9.35e-116 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
CGEHFNKO_00782 9.63e-60 yozN - - - - - - -
CGEHFNKO_00783 6.36e-50 yocN - - - - - - -
CGEHFNKO_00784 5.32e-75 yozO - - S - - - Bacterial PH domain
CGEHFNKO_00786 4.69e-43 yozC - - - - - - -
CGEHFNKO_00787 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
CGEHFNKO_00788 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
CGEHFNKO_00789 4.76e-212 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
CGEHFNKO_00790 1.19e-297 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
CGEHFNKO_00791 1.99e-214 yocS - - S ko:K03453 - ko00000 -transporter
CGEHFNKO_00792 3.4e-179 - - - S - - - Metallo-beta-lactamase superfamily
CGEHFNKO_00793 1.05e-262 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
CGEHFNKO_00794 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
CGEHFNKO_00795 0.0 yojO - - P - - - Von Willebrand factor
CGEHFNKO_00796 3.18e-206 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
CGEHFNKO_00797 1.87e-144 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CGEHFNKO_00798 2.12e-293 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
CGEHFNKO_00799 1.72e-287 - - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
CGEHFNKO_00800 9.47e-144 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CGEHFNKO_00802 1.89e-309 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
CGEHFNKO_00803 7.14e-194 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
CGEHFNKO_00804 6.41e-162 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
CGEHFNKO_00805 8.09e-80 yojF - - S - - - Protein of unknown function (DUF1806)
CGEHFNKO_00806 1.05e-30 - - - - - - - -
CGEHFNKO_00807 8.49e-210 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
CGEHFNKO_00808 4.68e-104 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
CGEHFNKO_00810 1.5e-88 iolK - - S - - - tautomerase
CGEHFNKO_00811 1.31e-90 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
CGEHFNKO_00812 1.2e-74 yodB - - K - - - transcriptional
CGEHFNKO_00813 1.35e-138 yodC - - C - - - nitroreductase
CGEHFNKO_00814 2.53e-142 yahD - - S ko:K06999 - ko00000 Carboxylesterase
CGEHFNKO_00815 3.12e-221 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
CGEHFNKO_00816 1.97e-28 - - - S - - - Protein of unknown function (DUF3311)
CGEHFNKO_00817 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CGEHFNKO_00818 0.0 - 3.2.1.45 GH30 M ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 ko00000,ko00001,ko01000 Glycosyl hydrolase family 30 beta sandwich domain
CGEHFNKO_00819 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
CGEHFNKO_00820 2.49e-169 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
CGEHFNKO_00821 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
CGEHFNKO_00822 1.02e-164 yodH - - Q - - - Methyltransferase
CGEHFNKO_00823 1.68e-50 yodI - - - - - - -
CGEHFNKO_00824 7.76e-193 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
CGEHFNKO_00825 1.05e-161 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
CGEHFNKO_00827 1.16e-72 yodL - - S - - - YodL-like
CGEHFNKO_00828 5.26e-134 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
CGEHFNKO_00829 9.77e-34 yozD - - S - - - YozD-like protein
CGEHFNKO_00831 1.9e-161 yodN - - - - - - -
CGEHFNKO_00832 2.45e-48 yozE - - S - - - Belongs to the UPF0346 family
CGEHFNKO_00833 1.4e-62 yokU - - S - - - YokU-like protein, putative antitoxin
CGEHFNKO_00834 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
CGEHFNKO_00835 9.47e-202 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
CGEHFNKO_00836 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
CGEHFNKO_00837 9.36e-160 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
CGEHFNKO_00838 6.87e-161 atoD 2.8.3.8, 2.8.3.9 - I ko:K01034 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CGEHFNKO_00839 5.89e-313 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CGEHFNKO_00840 2.29e-81 - - - L - - - Bacterial transcription activator, effector binding domain
CGEHFNKO_00842 9.87e-186 yiiD - - K ko:K06323 - ko00000 acetyltransferase
CGEHFNKO_00843 7.37e-315 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
CGEHFNKO_00844 4.72e-62 cgeC - - - ko:K06321 - ko00000 -
CGEHFNKO_00845 2.46e-87 cgeA - - - ko:K06319 - ko00000 -
CGEHFNKO_00846 1.34e-232 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
CGEHFNKO_00847 1.11e-282 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
CGEHFNKO_00848 3.54e-95 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
CGEHFNKO_00853 4.76e-24 yoqH - - M - - - LysM domain
CGEHFNKO_00854 2.1e-249 - - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
CGEHFNKO_00856 2.06e-217 - - - S - - - amine dehydrogenase activity
CGEHFNKO_00860 4.63e-13 - - - S - - - Acetyltransferase (GNAT) domain
CGEHFNKO_00861 2.48e-110 yokK - - S - - - SMI1 / KNR4 family
CGEHFNKO_00862 1.08e-264 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
CGEHFNKO_00863 6.57e-113 - - - G - - - SMI1-KNR4 cell-wall
CGEHFNKO_00864 5.15e-109 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
CGEHFNKO_00865 0.0 yokA - - L - - - Recombinase
CGEHFNKO_00866 1.02e-135 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
CGEHFNKO_00867 4.61e-106 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
CGEHFNKO_00868 1.2e-133 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CGEHFNKO_00869 3.35e-89 ypoP - - K - - - transcriptional
CGEHFNKO_00870 4.79e-127 ypmS - - S - - - protein conserved in bacteria
CGEHFNKO_00871 5e-174 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
CGEHFNKO_00872 7.51e-145 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
CGEHFNKO_00873 8.98e-55 ypmP - - S - - - Protein of unknown function (DUF2535)
CGEHFNKO_00874 3.49e-308 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CGEHFNKO_00875 1.05e-226 yplP - - K - - - Transcriptional regulator
CGEHFNKO_00876 3.69e-143 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
CGEHFNKO_00877 6.97e-150 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
CGEHFNKO_00878 5.2e-118 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CGEHFNKO_00879 1.78e-203 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CGEHFNKO_00880 6.48e-148 ypjP - - S - - - YpjP-like protein
CGEHFNKO_00881 1e-171 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
CGEHFNKO_00882 4.8e-99 yphP - - S - - - Belongs to the UPF0403 family
CGEHFNKO_00883 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
CGEHFNKO_00884 4.02e-204 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
CGEHFNKO_00885 1.14e-128 yagB - - S ko:K06950 - ko00000 phosphohydrolase
CGEHFNKO_00886 3.93e-113 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
CGEHFNKO_00887 5.43e-226 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CGEHFNKO_00888 1.56e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
CGEHFNKO_00889 5.12e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
CGEHFNKO_00890 1.27e-17 degR - - - - - - -
CGEHFNKO_00891 1.13e-49 - - - S - - - Protein of unknown function (DUF2564)
CGEHFNKO_00892 1.56e-38 ypeQ - - S - - - Zinc-finger
CGEHFNKO_00893 2.06e-159 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
CGEHFNKO_00894 2.79e-154 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CGEHFNKO_00895 5.83e-87 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
CGEHFNKO_00897 9.55e-210 ypcP - - L - - - 5'3' exonuclease
CGEHFNKO_00898 2.44e-10 - - - - - - - -
CGEHFNKO_00899 7.03e-53 ypbS - - S - - - Protein of unknown function (DUF2533)
CGEHFNKO_00900 0.0 ypbR - - S - - - Dynamin family
CGEHFNKO_00901 1.26e-117 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
CGEHFNKO_00902 8.68e-268 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
CGEHFNKO_00903 5.74e-142 - - - J - - - Acetyltransferase (GNAT) domain
CGEHFNKO_00904 3.67e-65 MGMT - - L ko:K07443 - ko00000 6-O-methylguanine DNA methyltransferase, DNA binding domain
CGEHFNKO_00905 1.53e-12 - - - S - - - Bacillus cereus group antimicrobial protein
CGEHFNKO_00906 1.63e-40 ydfR - - S - - - Protein of unknown function (DUF421)
CGEHFNKO_00907 2.37e-49 ydfR - - S - - - Protein of unknown function (DUF421)
CGEHFNKO_00908 2.19e-130 yrdC - - Q - - - Isochorismatase family
CGEHFNKO_00909 2.23e-07 - - - S - - - Bacillus cereus group antimicrobial protein
CGEHFNKO_00910 5.22e-91 - - - S - - - Protein of unknown function (DUF3800)
CGEHFNKO_00911 1.29e-33 - - - K - - - Helix-turn-helix domain
CGEHFNKO_00913 3.6e-13 - - - L - - - Membrane
CGEHFNKO_00914 2.47e-103 tagE 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
CGEHFNKO_00917 1.09e-84 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 Ami_2
CGEHFNKO_00918 9.16e-76 - - - S - - - Pfam:Phage_holin_4_1
CGEHFNKO_00919 4.85e-07 - - - S - - - Phage uncharacterised protein (Phage_XkdX)
CGEHFNKO_00920 0.000763 - - - - - - - -
CGEHFNKO_00921 1.06e-120 - - - - - - - -
CGEHFNKO_00922 0.0 - - - S - - - Peptidase_G2, IMC autoproteolytic cleavage domain
CGEHFNKO_00923 1.08e-286 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
CGEHFNKO_00924 3.24e-133 - - - S - - - Phage tail protein
CGEHFNKO_00925 0.0 - - - D - - - phage tail tape measure protein
CGEHFNKO_00926 6.81e-06 - - - - - - - -
CGEHFNKO_00927 3.42e-105 - - - S - - - Phage tail tube protein
CGEHFNKO_00929 3.27e-64 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
CGEHFNKO_00930 6.9e-55 - - - S - - - Phage head-tail joining protein
CGEHFNKO_00931 9.84e-51 - - - S - - - Phage gp6-like head-tail connector protein
CGEHFNKO_00932 4.39e-36 - - - - - - - -
CGEHFNKO_00933 3.19e-198 - - - S - - - capsid protein
CGEHFNKO_00934 2.77e-104 - - - S - - - peptidase activity
CGEHFNKO_00935 8.65e-217 - - - S - - - Phage portal protein
CGEHFNKO_00936 0.0 - - - S - - - Terminase
CGEHFNKO_00937 4.94e-100 - - - L - - - phage terminase small subunit
CGEHFNKO_00939 1.87e-20 - - - - - - - -
CGEHFNKO_00940 4.66e-94 - - - - - - - -
CGEHFNKO_00941 8.82e-25 - - - K - - - Transcriptional regulator
CGEHFNKO_00944 8.61e-18 - - - K - - - Transcriptional regulator
CGEHFNKO_00946 2.5e-89 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
CGEHFNKO_00950 1.07e-28 yqaO - - S - - - Phage-like element PBSX protein XtrA
CGEHFNKO_00952 9.21e-78 rusA - - L - - - Endodeoxyribonuclease RusA
CGEHFNKO_00954 9.54e-151 yqaM - - L - - - IstB-like ATP binding protein
CGEHFNKO_00955 1.46e-100 yqaL - - L - - - DnaD domain protein
CGEHFNKO_00957 2.99e-79 pi112 - - L - - - PDDEXK-like domain of unknown function (DUF3799)
CGEHFNKO_00958 5.31e-126 - - - - - - - -
CGEHFNKO_00962 6.88e-112 - - - - - - - -
CGEHFNKO_00963 1.44e-49 - - - K ko:K07741 - ko00000 AntA/AntB antirepressor
CGEHFNKO_00964 9.31e-46 - - - - - - - -
CGEHFNKO_00965 1.33e-21 - - - K - - - Helix-turn-helix XRE-family like proteins
CGEHFNKO_00966 1.27e-175 - - - L - - - Belongs to the 'phage' integrase family
CGEHFNKO_00967 1.77e-298 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine
CGEHFNKO_00968 4.04e-129 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
CGEHFNKO_00969 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CGEHFNKO_00970 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
CGEHFNKO_00972 6.91e-31 - - - S - - - YpzG-like protein
CGEHFNKO_00973 2.32e-276 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
CGEHFNKO_00974 5.52e-61 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
CGEHFNKO_00975 7.71e-128 ypsA - - S - - - Belongs to the UPF0398 family
CGEHFNKO_00976 9.36e-48 cotD - - S ko:K06327 - ko00000 Inner spore coat protein D
CGEHFNKO_00977 6.67e-301 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
CGEHFNKO_00978 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
CGEHFNKO_00979 1.21e-115 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
CGEHFNKO_00980 1.85e-95 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
CGEHFNKO_00981 7.53e-80 yppG - - S - - - YppG-like protein
CGEHFNKO_00985 0.000542 - - - - ko:K06430 - ko00000 -
CGEHFNKO_00986 1.92e-237 yppC - - S - - - Protein of unknown function (DUF2515)
CGEHFNKO_00987 8.84e-146 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
CGEHFNKO_00988 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
CGEHFNKO_00989 4.26e-118 ypoC - - - - - - -
CGEHFNKO_00990 1.45e-157 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CGEHFNKO_00991 9.8e-167 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
CGEHFNKO_00992 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
CGEHFNKO_00993 1.03e-283 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
CGEHFNKO_00994 9.65e-105 ypmB - - S - - - protein conserved in bacteria
CGEHFNKO_00995 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
CGEHFNKO_00996 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
CGEHFNKO_00997 2.82e-83 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CGEHFNKO_00998 3.3e-201 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CGEHFNKO_00999 1.14e-192 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
CGEHFNKO_01000 9.42e-232 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
CGEHFNKO_01001 3.99e-278 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CGEHFNKO_01002 8.54e-268 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
CGEHFNKO_01003 4.48e-170 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
CGEHFNKO_01004 6.19e-94 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
CGEHFNKO_01005 2.8e-188 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
CGEHFNKO_01006 2.47e-74 ypjD - - S - - - Nucleotide pyrophosphohydrolase
CGEHFNKO_01007 4.31e-199 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
CGEHFNKO_01008 1.3e-285 - 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
CGEHFNKO_01009 5.87e-182 ypjB - - S - - - sporulation protein
CGEHFNKO_01010 4.37e-135 ypjA - - S - - - membrane
CGEHFNKO_01011 4.02e-191 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
CGEHFNKO_01012 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
CGEHFNKO_01013 2.86e-127 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
CGEHFNKO_01014 8.2e-102 ypiF - - S - - - Protein of unknown function (DUF2487)
CGEHFNKO_01015 2.6e-129 ypiB - - S - - - Belongs to the UPF0302 family
CGEHFNKO_01016 1.76e-297 ypiA - - S - - - COG0457 FOG TPR repeat
CGEHFNKO_01017 2.44e-302 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
CGEHFNKO_01018 1.52e-261 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
CGEHFNKO_01019 2.14e-257 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CGEHFNKO_01020 2.8e-187 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
CGEHFNKO_01021 8.58e-291 trpB 4.2.1.20 - E ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
CGEHFNKO_01022 1.29e-150 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
CGEHFNKO_01023 2.46e-169 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
CGEHFNKO_01024 2.89e-212 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CGEHFNKO_01025 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CGEHFNKO_01026 2.93e-79 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
CGEHFNKO_01027 7.79e-261 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CGEHFNKO_01028 9.75e-276 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CGEHFNKO_01029 1.01e-180 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
CGEHFNKO_01030 2.86e-102 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
CGEHFNKO_01031 2.29e-251 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
CGEHFNKO_01032 7.76e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
CGEHFNKO_01033 3.96e-177 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
CGEHFNKO_01034 6.23e-47 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
CGEHFNKO_01035 6.27e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
CGEHFNKO_01036 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
CGEHFNKO_01037 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CGEHFNKO_01038 1.97e-172 yphF - - - - - - -
CGEHFNKO_01039 3.25e-23 yphE - - S - - - Protein of unknown function (DUF2768)
CGEHFNKO_01040 4.93e-244 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
CGEHFNKO_01041 0.0 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
CGEHFNKO_01042 8.79e-136 yphA - - - - - - -
CGEHFNKO_01043 1.87e-12 - - - S - - - YpzI-like protein
CGEHFNKO_01044 4.17e-238 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
CGEHFNKO_01045 6.69e-263 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
CGEHFNKO_01046 8.24e-146 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
CGEHFNKO_01047 7.86e-18 - - - S - - - Family of unknown function (DUF5359)
CGEHFNKO_01048 4.02e-73 ypfA - - M - - - Flagellar protein YcgR
CGEHFNKO_01049 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
CGEHFNKO_01050 3.77e-213 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
CGEHFNKO_01051 6.4e-156 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
CGEHFNKO_01052 3.73e-239 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
CGEHFNKO_01053 1.81e-311 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
CGEHFNKO_01054 3.35e-137 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
CGEHFNKO_01055 1.4e-190 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
CGEHFNKO_01056 1.92e-111 ypbF - - S - - - Protein of unknown function (DUF2663)
CGEHFNKO_01057 6.15e-126 ypbE - - M - - - Lysin motif
CGEHFNKO_01058 1.09e-128 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
CGEHFNKO_01059 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
CGEHFNKO_01060 2.58e-254 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
CGEHFNKO_01061 5.88e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
CGEHFNKO_01062 1.52e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CGEHFNKO_01063 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CGEHFNKO_01064 1.61e-253 rsiX - - - - - - -
CGEHFNKO_01065 3.22e-135 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
CGEHFNKO_01066 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
CGEHFNKO_01067 9.77e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CGEHFNKO_01068 4.39e-252 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
CGEHFNKO_01069 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
CGEHFNKO_01070 4.31e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
CGEHFNKO_01071 1.49e-167 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
CGEHFNKO_01072 8.99e-116 spmB - - S ko:K06374 - ko00000 Spore maturation protein
CGEHFNKO_01073 3.75e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
CGEHFNKO_01074 1.62e-275 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
CGEHFNKO_01075 1.51e-122 ypuI - - S - - - Protein of unknown function (DUF3907)
CGEHFNKO_01076 2.73e-133 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CGEHFNKO_01077 1.72e-165 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CGEHFNKO_01079 5.71e-121 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
CGEHFNKO_01080 2.74e-84 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CGEHFNKO_01081 6.92e-106 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
CGEHFNKO_01082 1.04e-290 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CGEHFNKO_01083 3.97e-144 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
CGEHFNKO_01084 2.27e-269 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CGEHFNKO_01085 4.92e-71 ypuD - - - - - - -
CGEHFNKO_01086 6.56e-131 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
CGEHFNKO_01087 1.66e-106 ccdC1 - - O - - - Protein of unknown function (DUF1453)
CGEHFNKO_01088 4.12e-104 ppiB 5.2.1.8 - O ko:K01802,ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CGEHFNKO_01089 7.69e-200 ypuA - - S - - - Secreted protein
CGEHFNKO_01090 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
CGEHFNKO_01091 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
CGEHFNKO_01092 8.82e-141 - - - S ko:K06407 - ko00000 stage V sporulation protein
CGEHFNKO_01093 1.51e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
CGEHFNKO_01094 8.19e-244 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
CGEHFNKO_01095 2.85e-103 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
CGEHFNKO_01096 1.43e-78 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
CGEHFNKO_01097 4.7e-143 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
CGEHFNKO_01098 1.32e-171 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CGEHFNKO_01099 4.77e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
CGEHFNKO_01100 4.86e-77 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
CGEHFNKO_01101 3.52e-273 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
CGEHFNKO_01102 1.1e-192 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CGEHFNKO_01103 4.97e-294 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
CGEHFNKO_01104 7.9e-214 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
CGEHFNKO_01105 2.73e-50 - - - S - - - Protein of unknown function (DUF4227)
CGEHFNKO_01106 4.56e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
CGEHFNKO_01107 3.53e-142 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
CGEHFNKO_01109 4.38e-47 yqkK - - - - - - -
CGEHFNKO_01110 1.96e-30 - - - - - - - -
CGEHFNKO_01111 4.12e-310 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
CGEHFNKO_01112 4.33e-314 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
CGEHFNKO_01113 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
CGEHFNKO_01114 1.3e-240 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
CGEHFNKO_01115 1.15e-75 ansR - - K - - - Transcriptional regulator
CGEHFNKO_01116 1.19e-279 yqxK - - L - - - DNA helicase
CGEHFNKO_01117 3.49e-121 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
CGEHFNKO_01118 2.01e-10 - - - S - - - Protein of unknown function (DUF3936)
CGEHFNKO_01119 3.23e-218 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
CGEHFNKO_01120 1.45e-11 yqkE - - S - - - Protein of unknown function (DUF3886)
CGEHFNKO_01121 8.59e-228 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
CGEHFNKO_01122 7.88e-54 yqkC - - S - - - Protein of unknown function (DUF2552)
CGEHFNKO_01123 5.4e-80 yqkB - - S - - - Belongs to the HesB IscA family
CGEHFNKO_01124 1.11e-227 yqkA - - K - - - GrpB protein
CGEHFNKO_01125 2e-79 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
CGEHFNKO_01126 2.81e-115 yqjY - - K ko:K06977 - ko00000 acetyltransferase
CGEHFNKO_01127 1.63e-299 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CGEHFNKO_01128 1.12e-76 - - - S - - - YolD-like protein
CGEHFNKO_01130 1.18e-237 yueF - - S - - - transporter activity
CGEHFNKO_01132 7.67e-96 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CGEHFNKO_01133 6.33e-227 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
CGEHFNKO_01134 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
CGEHFNKO_01135 3.54e-182 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
CGEHFNKO_01136 1.75e-226 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
CGEHFNKO_01137 5.82e-187 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CGEHFNKO_01138 4.14e-176 - - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
CGEHFNKO_01139 9.58e-307 - 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
CGEHFNKO_01140 1.15e-280 - 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
CGEHFNKO_01141 0.0 - 1.6.5.5 - C ko:K00344 - ko00000,ko01000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
CGEHFNKO_01142 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
CGEHFNKO_01143 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
CGEHFNKO_01144 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
CGEHFNKO_01145 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
CGEHFNKO_01146 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
CGEHFNKO_01147 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
CGEHFNKO_01148 1.88e-166 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
CGEHFNKO_01149 1.12e-313 - 6.1.3.1, 6.2.1.3, 6.2.1.34 - IQ ko:K00666,ko:K01897,ko:K12508,ko:K22319 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
CGEHFNKO_01152 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
CGEHFNKO_01153 5.26e-123 nusG1 - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
CGEHFNKO_01154 3.21e-211 - - - K - - - LysR substrate binding domain
CGEHFNKO_01155 1.11e-66 - - - S - - - GlpM protein
CGEHFNKO_01156 1.27e-247 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
CGEHFNKO_01157 2.72e-190 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
CGEHFNKO_01158 2.2e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
CGEHFNKO_01159 2.77e-220 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
CGEHFNKO_01160 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CGEHFNKO_01161 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CGEHFNKO_01162 1.16e-302 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CGEHFNKO_01163 1.3e-34 yqzJ - - - - - - -
CGEHFNKO_01164 2.05e-191 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CGEHFNKO_01165 1.06e-258 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
CGEHFNKO_01166 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
CGEHFNKO_01167 2.69e-95 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
CGEHFNKO_01169 2.23e-124 yqjB - - S - - - protein conserved in bacteria
CGEHFNKO_01170 1.6e-219 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
CGEHFNKO_01171 2.58e-166 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
CGEHFNKO_01172 1.04e-141 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
CGEHFNKO_01173 6.81e-174 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
CGEHFNKO_01174 1.68e-99 yqiW - - S - - - Belongs to the UPF0403 family
CGEHFNKO_01175 2.46e-218 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
CGEHFNKO_01176 2.64e-286 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
CGEHFNKO_01177 1.7e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
CGEHFNKO_01178 1.46e-219 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
CGEHFNKO_01179 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
CGEHFNKO_01180 6.96e-263 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
CGEHFNKO_01181 1.58e-261 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
CGEHFNKO_01182 6.8e-195 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
CGEHFNKO_01183 0.0 bkdR - - KT - - - Transcriptional regulator
CGEHFNKO_01184 7.32e-46 yqzF - - S - - - Protein of unknown function (DUF2627)
CGEHFNKO_01185 4e-205 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CGEHFNKO_01186 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
CGEHFNKO_01187 4.36e-264 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
CGEHFNKO_01188 2.51e-260 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
CGEHFNKO_01189 6.9e-197 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
CGEHFNKO_01190 5.6e-272 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
CGEHFNKO_01191 1.56e-174 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
CGEHFNKO_01192 6.87e-137 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
CGEHFNKO_01194 2.78e-131 - - - P - - - Probably functions as a manganese efflux pump
CGEHFNKO_01195 6.93e-147 - - - K - - - Protein of unknown function (DUF1232)
CGEHFNKO_01197 9.67e-274 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
CGEHFNKO_01200 8.31e-274 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CGEHFNKO_01201 6.11e-187 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
CGEHFNKO_01202 2.96e-302 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
CGEHFNKO_01203 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
CGEHFNKO_01204 4.38e-102 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
CGEHFNKO_01205 2.51e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
CGEHFNKO_01206 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CGEHFNKO_01207 3.31e-206 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
CGEHFNKO_01208 2.67e-52 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CGEHFNKO_01209 1.6e-309 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CGEHFNKO_01210 3.05e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CGEHFNKO_01211 2.2e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CGEHFNKO_01212 1.36e-87 yqhY - - S - - - protein conserved in bacteria
CGEHFNKO_01213 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
CGEHFNKO_01214 2.32e-86 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
CGEHFNKO_01215 2.74e-94 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
CGEHFNKO_01216 7.03e-150 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
CGEHFNKO_01217 4.27e-130 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
CGEHFNKO_01218 6.09e-260 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
CGEHFNKO_01219 3.72e-55 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
CGEHFNKO_01220 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
CGEHFNKO_01221 1.4e-111 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
CGEHFNKO_01222 1.27e-220 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
CGEHFNKO_01223 9.89e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
CGEHFNKO_01224 6.82e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CGEHFNKO_01225 6.04e-249 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
CGEHFNKO_01226 3.99e-118 yqhR - - S - - - Conserved membrane protein YqhR
CGEHFNKO_01227 2.1e-220 yqhQ - - S - - - Protein of unknown function (DUF1385)
CGEHFNKO_01228 1.27e-81 yqhP - - - - - - -
CGEHFNKO_01229 7e-210 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
CGEHFNKO_01230 5.64e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
CGEHFNKO_01231 1.12e-204 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
CGEHFNKO_01232 3.18e-84 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
CGEHFNKO_01233 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CGEHFNKO_01234 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CGEHFNKO_01235 6.7e-264 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
CGEHFNKO_01236 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
CGEHFNKO_01237 5.29e-196 yqhG - - S - - - Bacterial protein YqhG of unknown function
CGEHFNKO_01238 2.31e-32 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
CGEHFNKO_01239 2.75e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
CGEHFNKO_01240 1.82e-181 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
CGEHFNKO_01241 1.89e-102 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
CGEHFNKO_01242 8.05e-157 yqxM - - - ko:K19433 - ko00000 -
CGEHFNKO_01243 1.69e-71 yqzG - - S - - - Protein of unknown function (DUF3889)
CGEHFNKO_01244 2e-36 yqzE - - S - - - YqzE-like protein
CGEHFNKO_01245 4.9e-83 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
CGEHFNKO_01246 6.35e-85 comGF - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
CGEHFNKO_01247 3.14e-26 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
CGEHFNKO_01248 2.37e-95 - - - NU ko:K02246,ko:K08084 - ko00000,ko00002,ko02044 Tfp pilus assembly protein FimT
CGEHFNKO_01249 4.46e-66 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
CGEHFNKO_01250 4.85e-235 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
CGEHFNKO_01251 3.84e-258 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CGEHFNKO_01252 4.53e-239 yqxL - - P - - - Mg2 transporter protein
CGEHFNKO_01253 1.86e-304 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
CGEHFNKO_01254 4.13e-190 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
CGEHFNKO_01256 1.15e-86 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
CGEHFNKO_01257 4.19e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
CGEHFNKO_01258 5.73e-156 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
CGEHFNKO_01259 1.07e-28 yqgW - - S - - - Protein of unknown function (DUF2759)
CGEHFNKO_01260 2.99e-65 dglA - - S - - - Thiamine-binding protein
CGEHFNKO_01261 6.3e-255 yqgU - - - - - - -
CGEHFNKO_01262 9.8e-282 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
CGEHFNKO_01263 2.05e-228 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
CGEHFNKO_01264 1.47e-275 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
CGEHFNKO_01265 5.38e-11 yqgO - - - - - - -
CGEHFNKO_01266 3.13e-128 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CGEHFNKO_01267 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
CGEHFNKO_01268 3.42e-68 yqzD - - - - - - -
CGEHFNKO_01269 2.5e-99 yqzC - - S - - - Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CGEHFNKO_01270 2.32e-188 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CGEHFNKO_01271 8.33e-186 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CGEHFNKO_01272 5.88e-199 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
CGEHFNKO_01273 6.1e-204 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
CGEHFNKO_01274 2.24e-206 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
CGEHFNKO_01275 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
CGEHFNKO_01276 6.78e-289 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
CGEHFNKO_01277 4.22e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
CGEHFNKO_01278 4.77e-100 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
CGEHFNKO_01279 1.08e-167 yqgB - - S - - - Protein of unknown function (DUF1189)
CGEHFNKO_01280 6.92e-62 yqfZ - - M ko:K06417 - ko00000 LysM domain
CGEHFNKO_01281 1.97e-256 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CGEHFNKO_01282 3.34e-80 yqfX - - S - - - membrane
CGEHFNKO_01283 7.06e-143 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
CGEHFNKO_01284 2.25e-100 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
CGEHFNKO_01285 5.44e-199 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
CGEHFNKO_01286 8.63e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
CGEHFNKO_01287 4.06e-212 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CGEHFNKO_01288 4.26e-308 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
CGEHFNKO_01289 8.85e-87 yqfQ - - S - - - YqfQ-like protein
CGEHFNKO_01290 1.18e-224 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CGEHFNKO_01291 1.53e-268 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CGEHFNKO_01292 4.93e-161 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
CGEHFNKO_01293 9.68e-83 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
CGEHFNKO_01294 3.97e-255 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
CGEHFNKO_01295 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
CGEHFNKO_01296 1.36e-112 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
CGEHFNKO_01297 5.46e-192 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
CGEHFNKO_01298 5.89e-145 ccpN - - K - - - CBS domain
CGEHFNKO_01299 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
CGEHFNKO_01300 5.19e-223 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
CGEHFNKO_01301 8.73e-186 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
CGEHFNKO_01302 6e-24 - - - S - - - YqzL-like protein
CGEHFNKO_01303 1.42e-214 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CGEHFNKO_01304 1.92e-92 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
CGEHFNKO_01305 5.28e-83 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
CGEHFNKO_01306 1.44e-104 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CGEHFNKO_01307 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
CGEHFNKO_01308 2.47e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
CGEHFNKO_01309 1.07e-281 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
CGEHFNKO_01310 3.57e-61 yqfC - - S - - - sporulation protein YqfC
CGEHFNKO_01311 1.26e-85 yqfB - - - - - - -
CGEHFNKO_01312 4.48e-189 yqfA - - S - - - UPF0365 protein
CGEHFNKO_01313 1.49e-292 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
CGEHFNKO_01314 7.84e-91 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
CGEHFNKO_01315 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
CGEHFNKO_01316 1.67e-202 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
CGEHFNKO_01317 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
CGEHFNKO_01318 1.18e-179 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
CGEHFNKO_01319 1.55e-223 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
CGEHFNKO_01320 4.93e-266 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
CGEHFNKO_01321 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
CGEHFNKO_01322 2.99e-109 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CGEHFNKO_01323 2.73e-240 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
CGEHFNKO_01324 1.18e-275 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
CGEHFNKO_01325 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
CGEHFNKO_01326 2.1e-71 yqxA - - S - - - Protein of unknown function (DUF3679)
CGEHFNKO_01327 9.09e-280 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
CGEHFNKO_01328 2.51e-260 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CGEHFNKO_01329 1.91e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
CGEHFNKO_01330 3.84e-234 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
CGEHFNKO_01331 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
CGEHFNKO_01332 3.79e-136 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
CGEHFNKO_01333 2.06e-136 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
CGEHFNKO_01334 9.79e-192 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CGEHFNKO_01335 8.39e-179 yqeM - - Q - - - Methyltransferase
CGEHFNKO_01336 4.65e-80 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
CGEHFNKO_01337 2.38e-133 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
CGEHFNKO_01338 2.89e-140 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CGEHFNKO_01339 1.81e-60 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
CGEHFNKO_01340 1.63e-198 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CGEHFNKO_01341 1.95e-272 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
CGEHFNKO_01342 5.51e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
CGEHFNKO_01344 2.08e-177 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
CGEHFNKO_01345 8.09e-181 pdaC 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
CGEHFNKO_01346 3.41e-137 yqeD - - S - - - SNARE associated Golgi protein
CGEHFNKO_01347 7.26e-33 - 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
CGEHFNKO_01348 1.34e-278 - - - EGP - - - Transmembrane secretion effector
CGEHFNKO_01349 3.66e-72 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CGEHFNKO_01350 0.0 - - - L ko:K06400 - ko00000 Recombinase
CGEHFNKO_01351 2.45e-121 - - - EGP ko:K08164 - ko00000,ko02000 Arabinose efflux permease
CGEHFNKO_01352 3.43e-43 cadC3 - - K - - - transcriptional
CGEHFNKO_01353 6.32e-97 - - - P ko:K03449 - ko00000,ko02000 transporter
CGEHFNKO_01354 2.77e-194 - 1.8.5.5 - C ko:K08352 ko00920,ko01120,map00920,map01120 ko00000,ko00001,ko01000,ko02000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CGEHFNKO_01355 2.02e-96 yvbU - - K - - - Transcriptional regulator
CGEHFNKO_01356 3.18e-72 xkdA - - E - - - IrrE N-terminal-like domain
CGEHFNKO_01357 1.01e-78 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CGEHFNKO_01358 3.2e-205 - - - S - - - Carbohydrate esterase, sialic acid-specific acetylesterase
CGEHFNKO_01359 3.85e-120 - - - K - - - Transcriptional regulator PadR-like family
CGEHFNKO_01360 7.02e-189 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
CGEHFNKO_01361 1.84e-91 psiE - - S ko:K13256 - ko00000 Belongs to the PsiE family
CGEHFNKO_01362 1.54e-307 yrkQ - - T - - - Histidine kinase
CGEHFNKO_01363 6.87e-162 yrkP - - T ko:K02483 - ko00000,ko02022 Transcriptional regulator
CGEHFNKO_01364 3.66e-274 yrkO - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
CGEHFNKO_01365 4.15e-133 yrkN - - K - - - Acetyltransferase (GNAT) family
CGEHFNKO_01366 3.86e-128 yqaC - - F - - - adenylate kinase activity
CGEHFNKO_01367 6.43e-42 - - - K - - - acetyltransferase
CGEHFNKO_01368 1.96e-79 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 COG0477 Permeases of the major facilitator superfamily
CGEHFNKO_01369 1.74e-104 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
CGEHFNKO_01370 1.42e-122 - - - S - - - DinB family
CGEHFNKO_01372 1.45e-190 supH - - S - - - hydrolase
CGEHFNKO_01373 2.15e-109 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
CGEHFNKO_01374 4.12e-168 - - - K - - - Helix-turn-helix domain, rpiR family
CGEHFNKO_01375 6.94e-238 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
CGEHFNKO_01376 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
CGEHFNKO_01377 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
CGEHFNKO_01378 2.06e-234 romA - - S - - - Beta-lactamase superfamily domain
CGEHFNKO_01379 3.95e-108 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CGEHFNKO_01380 4.57e-212 yybE - - K - - - Transcriptional regulator
CGEHFNKO_01381 7.6e-270 yybF1 - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
CGEHFNKO_01382 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
CGEHFNKO_01383 1.6e-128 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
CGEHFNKO_01384 3.67e-120 yrhH - - Q - - - methyltransferase
CGEHFNKO_01385 2.37e-07 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
CGEHFNKO_01386 3.96e-183 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
CGEHFNKO_01387 1.54e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
CGEHFNKO_01388 0.0 yrhE 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
CGEHFNKO_01389 4.76e-106 yrhD - - S - - - Protein of unknown function (DUF1641)
CGEHFNKO_01390 1.92e-46 yrhC - - S - - - YrhC-like protein
CGEHFNKO_01391 9.25e-269 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
CGEHFNKO_01392 7.96e-219 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
CGEHFNKO_01393 5.64e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CGEHFNKO_01394 7.23e-155 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
CGEHFNKO_01395 1.78e-38 yrzA - - S - - - Protein of unknown function (DUF2536)
CGEHFNKO_01396 1.02e-123 yrrS - - S - - - Protein of unknown function (DUF1510)
CGEHFNKO_01397 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
CGEHFNKO_01398 1.62e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
CGEHFNKO_01399 2.61e-147 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
CGEHFNKO_01400 1.88e-312 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
CGEHFNKO_01401 2.2e-222 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
CGEHFNKO_01402 2.71e-152 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
CGEHFNKO_01403 2.82e-259 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CGEHFNKO_01404 7.2e-61 yrzB - - S - - - Belongs to the UPF0473 family
CGEHFNKO_01405 2.72e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CGEHFNKO_01406 1.1e-55 yrzL - - S - - - Belongs to the UPF0297 family
CGEHFNKO_01407 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CGEHFNKO_01408 4.67e-237 yrrI - - S - - - AI-2E family transporter
CGEHFNKO_01409 9.37e-170 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
CGEHFNKO_01410 3.14e-189 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
CGEHFNKO_01411 1.38e-140 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
CGEHFNKO_01412 1.54e-138 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
CGEHFNKO_01413 6.52e-13 - - - S - - - Protein of unknown function (DUF3918)
CGEHFNKO_01414 8.4e-42 yrzR - - - - - - -
CGEHFNKO_01415 1.76e-107 yrrD - - S - - - protein conserved in bacteria
CGEHFNKO_01416 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
CGEHFNKO_01417 1.12e-23 yrrB - - S - - - COG0457 FOG TPR repeat
CGEHFNKO_01418 3.55e-282 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
CGEHFNKO_01419 3.63e-270 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
CGEHFNKO_01420 9.19e-84 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
CGEHFNKO_01421 2.16e-302 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
CGEHFNKO_01422 1.66e-58 - - - L - - - transposase activity
CGEHFNKO_01423 1.54e-161 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
CGEHFNKO_01424 9.74e-178 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
CGEHFNKO_01425 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CGEHFNKO_01426 3e-310 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
CGEHFNKO_01429 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
CGEHFNKO_01430 2.86e-97 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
CGEHFNKO_01431 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CGEHFNKO_01432 5.1e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CGEHFNKO_01433 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
CGEHFNKO_01434 7.78e-63 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
CGEHFNKO_01435 2.45e-109 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
CGEHFNKO_01436 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CGEHFNKO_01437 3.45e-68 yrzD - - S - - - Post-transcriptional regulator
CGEHFNKO_01438 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CGEHFNKO_01439 2.03e-143 yrbG - - S - - - membrane
CGEHFNKO_01440 9.08e-81 yrzE - - S - - - Protein of unknown function (DUF3792)
CGEHFNKO_01441 2.09e-50 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
CGEHFNKO_01442 1.16e-292 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
CGEHFNKO_01443 5.79e-246 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CGEHFNKO_01444 9.76e-29 yrzS - - S - - - Protein of unknown function (DUF2905)
CGEHFNKO_01445 6.17e-237 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
CGEHFNKO_01446 2.33e-136 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
CGEHFNKO_01447 1.03e-121 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
CGEHFNKO_01449 8.92e-61 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
CGEHFNKO_01450 3.28e-252 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
CGEHFNKO_01451 6.76e-269 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CGEHFNKO_01452 3.69e-196 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
CGEHFNKO_01453 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
CGEHFNKO_01454 1.4e-285 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
CGEHFNKO_01455 1.23e-123 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
CGEHFNKO_01456 8.16e-206 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
CGEHFNKO_01457 5.94e-95 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
CGEHFNKO_01458 8.28e-310 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CGEHFNKO_01459 4.25e-139 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
CGEHFNKO_01460 7.74e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
CGEHFNKO_01461 1.66e-73 ysxB - - J ko:K07584 - ko00000 ribosomal protein
CGEHFNKO_01462 1.28e-65 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
CGEHFNKO_01463 3.59e-206 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
CGEHFNKO_01464 2.8e-188 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
CGEHFNKO_01465 3.94e-184 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
CGEHFNKO_01466 6.85e-155 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
CGEHFNKO_01467 6.14e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
CGEHFNKO_01468 4.34e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
CGEHFNKO_01469 1.06e-234 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
CGEHFNKO_01470 2.5e-164 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
CGEHFNKO_01471 8.25e-131 maf - - D ko:K06287 - ko00000 septum formation protein Maf
CGEHFNKO_01472 3.11e-209 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
CGEHFNKO_01473 3.79e-118 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
CGEHFNKO_01474 1.32e-307 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
CGEHFNKO_01475 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
CGEHFNKO_01476 1.53e-35 - - - - - - - -
CGEHFNKO_01477 1.89e-251 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CGEHFNKO_01478 3.51e-295 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
CGEHFNKO_01479 7.68e-311 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
CGEHFNKO_01480 1.98e-235 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
CGEHFNKO_01481 4.65e-183 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
CGEHFNKO_01482 5.19e-223 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
CGEHFNKO_01483 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
CGEHFNKO_01484 5.45e-316 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CGEHFNKO_01485 6.8e-115 ysxD - - - - - - -
CGEHFNKO_01486 3.1e-138 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
CGEHFNKO_01487 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CGEHFNKO_01488 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
CGEHFNKO_01489 3.28e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CGEHFNKO_01490 2.18e-287 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
CGEHFNKO_01491 1.35e-240 ysoA - - H - - - Tetratricopeptide repeat
CGEHFNKO_01492 3.77e-150 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CGEHFNKO_01493 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CGEHFNKO_01494 1.18e-252 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
CGEHFNKO_01495 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CGEHFNKO_01496 2.75e-244 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CGEHFNKO_01497 2.06e-109 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
CGEHFNKO_01498 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
CGEHFNKO_01501 6.85e-70 res - - L - - - Resolvase, N terminal domain
CGEHFNKO_01502 1.56e-161 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
CGEHFNKO_01503 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 Type I restriction-modification system
CGEHFNKO_01504 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
CGEHFNKO_01508 9.94e-120 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
CGEHFNKO_01509 1.59e-131 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CGEHFNKO_01510 1.44e-170 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CGEHFNKO_01511 7.73e-256 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
CGEHFNKO_01512 1.15e-196 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
CGEHFNKO_01513 3.77e-97 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
CGEHFNKO_01514 9.16e-200 - - - L - - - Recombinase
CGEHFNKO_01515 5.89e-09 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CGEHFNKO_01517 1.61e-21 - - - - - - - -
CGEHFNKO_01519 8.15e-233 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Aspartate phosphatase response regulator
CGEHFNKO_01520 1.04e-212 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
CGEHFNKO_01521 2.86e-33 - - - - - - - -
CGEHFNKO_01522 7.56e-116 yokH - - G - - - SMI1 / KNR4 family
CGEHFNKO_01523 9.44e-61 - - - V - - - HNH endonuclease
CGEHFNKO_01524 1.89e-158 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
CGEHFNKO_01525 2.63e-40 xhlB - - S - - - SPP1 phage holin
CGEHFNKO_01526 8.29e-39 xhlA - - S - - - Haemolysin XhlA
CGEHFNKO_01527 1.11e-24 xkdX - - - - - - -
CGEHFNKO_01529 3.98e-59 - - - - - - - -
CGEHFNKO_01530 1.06e-79 - - - - - - - -
CGEHFNKO_01531 9.77e-128 - - - S - - - homolog of phage Mu protein gp47
CGEHFNKO_01532 4.16e-33 - - - S - - - Protein of unknown function (DUF2634)
CGEHFNKO_01533 6.47e-35 - - - - - - - -
CGEHFNKO_01534 2.52e-109 - - - - - - - -
CGEHFNKO_01535 1.1e-30 - - - - - - - -
CGEHFNKO_01536 9.44e-55 - - - M - - - LysM domain
CGEHFNKO_01537 2.95e-178 - - - N - - - phage tail tape measure protein
CGEHFNKO_01538 1.65e-19 - - - - - - - -
CGEHFNKO_01539 7.88e-47 - - - - - - - -
CGEHFNKO_01540 1.25e-130 - - - S - - - Protein of unknown function (DUF3383)
CGEHFNKO_01541 2.96e-41 - - - - - - - -
CGEHFNKO_01543 6.02e-62 - - - - - - - -
CGEHFNKO_01545 6.27e-41 - - - S - - - Phage Mu protein F like protein
CGEHFNKO_01547 8.89e-154 - - - S - - - P22 coat protein - gene protein 5
CGEHFNKO_01548 2.44e-66 - - - S - - - Domain of unknown function (DUF4355)
CGEHFNKO_01549 1.38e-50 - - - S - - - Protein of unknown function (DUF2829)
CGEHFNKO_01551 3.83e-193 - - - S - - - Phage portal protein, SPP1 Gp6-like
CGEHFNKO_01552 2.08e-230 - - - S - - - Terminase-like family
CGEHFNKO_01553 3.72e-103 yqaS - - L - - - DNA packaging
CGEHFNKO_01555 9.97e-62 - - - L - - - Transposase
CGEHFNKO_01559 2.43e-58 - - - - - - - -
CGEHFNKO_01568 9.56e-80 - - - S - - - dUTPase
CGEHFNKO_01571 1.05e-135 - 2.1.1.72 - L ko:K06223 ko03430,map03430 ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 D12 class N6 adenine-specific DNA methyltransferase
CGEHFNKO_01573 1.74e-10 - - - - - - - -
CGEHFNKO_01575 1.16e-23 yqaO - - S - - - Phage-like element PBSX protein XtrA
CGEHFNKO_01577 2.23e-71 - - - S - - - Protein of unknown function (DUF1064)
CGEHFNKO_01581 4.91e-71 - - - L ko:K02315 - ko00000,ko03032 Bacterial dnaA protein
CGEHFNKO_01583 6.49e-160 recT - - L ko:K07455 - ko00000,ko03400 RecT family
CGEHFNKO_01584 1.09e-192 yqaJ - - L - - - YqaJ-like viral recombinase domain
CGEHFNKO_01589 4.15e-113 - - - - - - - -
CGEHFNKO_01590 7.17e-38 - - - S - - - DNA binding
CGEHFNKO_01592 2.64e-26 - - - K - - - Helix-turn-helix XRE-family like proteins
CGEHFNKO_01593 6.95e-47 - - - K - - - sequence-specific DNA binding
CGEHFNKO_01594 1.62e-07 - - - - - - - -
CGEHFNKO_01595 3.4e-35 xkdA - - E - - - IrrE N-terminal-like domain
CGEHFNKO_01596 4.14e-25 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
CGEHFNKO_01597 2.67e-101 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
CGEHFNKO_01598 4.34e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
CGEHFNKO_01599 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
CGEHFNKO_01600 2.73e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
CGEHFNKO_01601 2.86e-102 yslB - - S - - - Protein of unknown function (DUF2507)
CGEHFNKO_01602 1.01e-273 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
CGEHFNKO_01603 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
CGEHFNKO_01604 1.6e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
CGEHFNKO_01605 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
CGEHFNKO_01606 2.48e-227 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
CGEHFNKO_01607 8.64e-178 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
CGEHFNKO_01608 4.1e-177 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
CGEHFNKO_01609 6.22e-134 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
CGEHFNKO_01610 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
CGEHFNKO_01611 9.83e-163 ywbB - - S - - - Protein of unknown function (DUF2711)
CGEHFNKO_01612 3.09e-88 yshE - - S ko:K08989 - ko00000 membrane
CGEHFNKO_01613 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
CGEHFNKO_01614 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
CGEHFNKO_01615 6.04e-109 yshB - - S - - - membrane protein, required for colicin V production
CGEHFNKO_01616 1.47e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CGEHFNKO_01617 7.57e-216 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CGEHFNKO_01618 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CGEHFNKO_01619 2.19e-249 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CGEHFNKO_01620 1.89e-172 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CGEHFNKO_01621 1.07e-43 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
CGEHFNKO_01622 2.15e-262 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
CGEHFNKO_01623 0.0 - 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD binding domain
CGEHFNKO_01624 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
CGEHFNKO_01625 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
CGEHFNKO_01626 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
CGEHFNKO_01627 6.84e-191 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
CGEHFNKO_01628 4.38e-215 araP - - P ko:K10189,ko:K10241,ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PFAM binding-protein-dependent transport systems inner membrane component
CGEHFNKO_01629 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
CGEHFNKO_01630 4.72e-285 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
CGEHFNKO_01631 5.07e-180 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
CGEHFNKO_01632 3.43e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
CGEHFNKO_01633 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
CGEHFNKO_01634 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
CGEHFNKO_01635 1.71e-241 abnA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
CGEHFNKO_01636 1.85e-263 ysdC - - G - - - COG1363 Cellulase M and related proteins
CGEHFNKO_01637 9.71e-90 ysdB - - S - - - Sigma-w pathway protein YsdB
CGEHFNKO_01638 1.56e-55 ysdA - - S - - - Membrane
CGEHFNKO_01639 2.3e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CGEHFNKO_01640 1.95e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
CGEHFNKO_01641 1.79e-112 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CGEHFNKO_01642 3.1e-147 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
CGEHFNKO_01643 2.76e-69 - - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 effector of murein hydrolase LrgA
CGEHFNKO_01644 1.05e-167 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
CGEHFNKO_01645 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
CGEHFNKO_01646 7.21e-194 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
CGEHFNKO_01647 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CGEHFNKO_01648 5.7e-197 ytxC - - S - - - YtxC-like family
CGEHFNKO_01649 5.42e-141 ytxB - - S - - - SNARE associated Golgi protein
CGEHFNKO_01650 1.66e-218 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
CGEHFNKO_01651 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
CGEHFNKO_01652 5.95e-106 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CGEHFNKO_01653 1.82e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CGEHFNKO_01654 2.19e-249 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
CGEHFNKO_01655 1.69e-89 ytcD - - K - - - Transcriptional regulator
CGEHFNKO_01656 6.86e-260 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
CGEHFNKO_01657 7.54e-204 ytbE - - S - - - reductase
CGEHFNKO_01658 4.87e-127 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CGEHFNKO_01659 2e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
CGEHFNKO_01660 1.91e-200 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
CGEHFNKO_01661 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CGEHFNKO_01662 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
CGEHFNKO_01663 1.38e-165 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CGEHFNKO_01664 3.62e-218 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
CGEHFNKO_01665 1.32e-308 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
CGEHFNKO_01666 5.78e-268 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
CGEHFNKO_01668 9.37e-256 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Aspartate phosphatase response regulator
CGEHFNKO_01669 1.32e-69 - - - - - - - -
CGEHFNKO_01670 5.5e-83 yjdF3 - - S - - - Protein of unknown function (DUF2992)
CGEHFNKO_01671 1.14e-95 ytwI - - S - - - membrane
CGEHFNKO_01672 4.05e-247 ytvI - - S - - - sporulation integral membrane protein YtvI
CGEHFNKO_01673 3.42e-84 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
CGEHFNKO_01674 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
CGEHFNKO_01675 3.98e-230 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
CGEHFNKO_01676 2.7e-231 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
CGEHFNKO_01677 1.46e-206 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CGEHFNKO_01678 1.72e-286 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
CGEHFNKO_01679 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
CGEHFNKO_01680 4.94e-75 ytrH - - S - - - Sporulation protein YtrH
CGEHFNKO_01681 2.17e-113 ytrI - - - - - - -
CGEHFNKO_01682 7.04e-32 - - - - - - - -
CGEHFNKO_01683 2.14e-231 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
CGEHFNKO_01684 3.05e-63 ytpI - - S - - - YtpI-like protein
CGEHFNKO_01685 6.77e-305 ytoI - - K - - - transcriptional regulator containing CBS domains
CGEHFNKO_01686 8.4e-166 ytkL - - S - - - Belongs to the UPF0173 family
CGEHFNKO_01687 2.06e-184 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CGEHFNKO_01689 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
CGEHFNKO_01690 8.67e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
CGEHFNKO_01691 7.81e-113 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
CGEHFNKO_01692 9.47e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CGEHFNKO_01693 8.73e-234 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
CGEHFNKO_01694 1.36e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CGEHFNKO_01695 4.77e-100 ytfJ - - S - - - Sporulation protein YtfJ
CGEHFNKO_01696 5.2e-156 ytfI - - S - - - Protein of unknown function (DUF2953)
CGEHFNKO_01697 1.13e-113 yteJ - - S - - - RDD family
CGEHFNKO_01698 7.46e-234 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
CGEHFNKO_01699 1.91e-195 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CGEHFNKO_01700 0.0 ytcJ - - S - - - amidohydrolase
CGEHFNKO_01701 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
CGEHFNKO_01702 2.05e-42 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
CGEHFNKO_01703 2.01e-285 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CGEHFNKO_01704 1.66e-267 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
CGEHFNKO_01705 1.68e-309 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
CGEHFNKO_01706 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CGEHFNKO_01707 1.77e-197 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
CGEHFNKO_01708 2.41e-141 yttP - - K - - - Transcriptional regulator
CGEHFNKO_01709 5.2e-113 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
CGEHFNKO_01710 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
CGEHFNKO_01711 2.34e-140 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CGEHFNKO_01712 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
CGEHFNKO_01713 1.43e-129 yokH - - G - - - SMI1 / KNR4 family
CGEHFNKO_01714 6.45e-284 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CGEHFNKO_01716 1.65e-118 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
CGEHFNKO_01718 2.49e-178 - - - E - - - GDSL-like Lipase/Acylhydrolase family
CGEHFNKO_01719 4.99e-193 - - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CGEHFNKO_01720 7.76e-191 - - - K - - - Transcriptional regulator
CGEHFNKO_01721 5.77e-160 ygaZ - - E - - - AzlC protein
CGEHFNKO_01722 3.06e-64 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
CGEHFNKO_01723 9.91e-303 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CGEHFNKO_01724 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
CGEHFNKO_01725 2.84e-155 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
CGEHFNKO_01726 1.02e-150 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
CGEHFNKO_01727 3.91e-290 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
CGEHFNKO_01728 1.05e-155 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
CGEHFNKO_01729 3.01e-185 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
CGEHFNKO_01730 5.91e-235 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
CGEHFNKO_01731 1.54e-249 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
CGEHFNKO_01732 2.41e-57 ytxJ - - O - - - Protein of unknown function (DUF2847)
CGEHFNKO_01733 1.83e-30 ytxH - - S - - - COG4980 Gas vesicle protein
CGEHFNKO_01734 5.38e-26 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CGEHFNKO_01735 9.62e-317 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
CGEHFNKO_01736 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
CGEHFNKO_01737 2.08e-139 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CGEHFNKO_01738 1.69e-190 ytpQ - - S - - - Belongs to the UPF0354 family
CGEHFNKO_01739 5.47e-76 ytpP - - CO - - - Thioredoxin
CGEHFNKO_01740 1.42e-102 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
CGEHFNKO_01741 5.06e-259 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
CGEHFNKO_01742 9.96e-69 ytzB - - S - - - small secreted protein
CGEHFNKO_01743 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
CGEHFNKO_01744 4.57e-210 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
CGEHFNKO_01745 6.43e-160 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
CGEHFNKO_01746 3.88e-60 ytzH - - S - - - YtzH-like protein
CGEHFNKO_01747 2.93e-199 ytmP - - M - - - Phosphotransferase
CGEHFNKO_01748 1.33e-223 ytlR - - I - - - Diacylglycerol kinase catalytic domain
CGEHFNKO_01749 4.05e-214 ytlQ - - - - - - -
CGEHFNKO_01750 8.66e-130 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CGEHFNKO_01751 2.38e-222 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
CGEHFNKO_01752 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
CGEHFNKO_01753 2.46e-289 pbuO - - S ko:K06901 - ko00000,ko02000 permease
CGEHFNKO_01754 1.23e-276 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
CGEHFNKO_01755 7.72e-165 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
CGEHFNKO_01756 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
CGEHFNKO_01757 8.68e-169 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
CGEHFNKO_01758 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CGEHFNKO_01759 3.73e-299 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
CGEHFNKO_01760 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
CGEHFNKO_01761 2.14e-36 yteV - - S - - - Sporulation protein Cse60
CGEHFNKO_01762 3.18e-238 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
CGEHFNKO_01763 9.7e-312 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
CGEHFNKO_01764 2.65e-216 - - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
CGEHFNKO_01765 2.54e-61 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
CGEHFNKO_01766 1.42e-96 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
CGEHFNKO_01767 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
CGEHFNKO_01768 1.98e-110 - - - M - - - Acetyltransferase (GNAT) domain
CGEHFNKO_01769 1.22e-68 ytwF - - P - - - Sulfurtransferase
CGEHFNKO_01770 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
CGEHFNKO_01771 7.19e-69 ytvB - - S - - - Protein of unknown function (DUF4257)
CGEHFNKO_01772 1.07e-177 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
CGEHFNKO_01786 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
CGEHFNKO_01787 2.04e-66 - - - L - - - transposase activity
CGEHFNKO_01788 2.56e-270 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
CGEHFNKO_01789 7.57e-211 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
CGEHFNKO_01790 0.0 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
CGEHFNKO_01791 5.06e-195 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
CGEHFNKO_01792 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CGEHFNKO_01793 0.0 - - - M - - - Glycosyltransferase like family 2
CGEHFNKO_01794 2.69e-91 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
CGEHFNKO_01795 3.69e-183 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
CGEHFNKO_01796 5.25e-279 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CGEHFNKO_01797 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
CGEHFNKO_01798 9.14e-239 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
CGEHFNKO_01799 0.0 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
CGEHFNKO_01800 2.36e-249 gerBB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
CGEHFNKO_01801 1e-270 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
CGEHFNKO_01802 0.0 - - - J ko:K07011 - ko00000 Glycosyl transferase family 2
CGEHFNKO_01803 8.17e-316 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
CGEHFNKO_01804 1.14e-229 ywtF_2 - - K - - - Transcriptional regulator
CGEHFNKO_01805 7.5e-202 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
CGEHFNKO_01806 3.91e-78 yttA - - S - - - Pfam Transposase IS66
CGEHFNKO_01807 3.88e-304 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
CGEHFNKO_01808 4.04e-29 ywtC - - - - - - -
CGEHFNKO_01809 5.68e-280 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
CGEHFNKO_01810 2.95e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
CGEHFNKO_01811 4.19e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
CGEHFNKO_01812 1.26e-241 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
CGEHFNKO_01813 2.09e-245 - - - E - - - Spore germination protein
CGEHFNKO_01814 1.25e-231 gerKC - - S - - - Spore germination B3/ GerAC like, C-terminal
CGEHFNKO_01815 4.28e-228 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
CGEHFNKO_01816 2.94e-203 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CGEHFNKO_01817 4.8e-86 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
CGEHFNKO_01818 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
CGEHFNKO_01819 1.54e-204 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
CGEHFNKO_01820 6.93e-208 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
CGEHFNKO_01821 1.18e-115 batE - - T - - - Sh3 type 3 domain protein
CGEHFNKO_01822 2.13e-124 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
CGEHFNKO_01823 5.71e-191 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
CGEHFNKO_01824 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
CGEHFNKO_01825 7.59e-215 alsR - - K - - - LysR substrate binding domain
CGEHFNKO_01826 5.18e-307 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CGEHFNKO_01827 3.43e-163 ywrJ - - - - - - -
CGEHFNKO_01828 1.24e-183 cotB - - - ko:K06325 - ko00000 -
CGEHFNKO_01829 2.27e-270 cotH - - M ko:K06330 - ko00000 Spore Coat
CGEHFNKO_01830 2.82e-20 - - - - - - - -
CGEHFNKO_01831 9.88e-145 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CGEHFNKO_01832 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
CGEHFNKO_01833 1.44e-109 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
CGEHFNKO_01834 2e-130 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
CGEHFNKO_01835 6.07e-114 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
CGEHFNKO_01836 4.15e-171 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
CGEHFNKO_01837 9.61e-121 - - - - - - - -
CGEHFNKO_01838 1.93e-85 - - - S ko:K21494 - ko00000,ko02048 SMI1 / KNR4 family (SUKH-1)
CGEHFNKO_01839 3.84e-136 - - - S - - - Domain of unknown function (DUF1851)
CGEHFNKO_01840 0.0 ywqJ - - S - - - Pre-toxin TG
CGEHFNKO_01841 5.99e-50 ywqI - - S - - - Family of unknown function (DUF5344)
CGEHFNKO_01844 5.69e-190 ywqG - - S - - - Domain of unknown function (DUF1963)
CGEHFNKO_01845 8.35e-312 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CGEHFNKO_01846 4.31e-181 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
CGEHFNKO_01847 8.99e-157 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
CGEHFNKO_01848 3.53e-152 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
CGEHFNKO_01849 1.74e-21 - - - - - - - -
CGEHFNKO_01850 0.0 ywqB - - S - - - SWIM zinc finger
CGEHFNKO_01851 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
CGEHFNKO_01852 3.72e-202 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
CGEHFNKO_01853 4.82e-181 glcR - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
CGEHFNKO_01854 1.47e-76 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
CGEHFNKO_01855 4.49e-82 ywpG - - - - - - -
CGEHFNKO_01856 2.63e-90 ywpF - - S - - - YwpF-like protein
CGEHFNKO_01857 7.6e-74 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
CGEHFNKO_01858 3.15e-98 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
CGEHFNKO_01859 1.63e-258 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
CGEHFNKO_01860 4.64e-188 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
CGEHFNKO_01861 2.96e-173 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
CGEHFNKO_01862 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
CGEHFNKO_01863 5.93e-60 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
CGEHFNKO_01864 3.58e-93 ywoH - - K - - - transcriptional
CGEHFNKO_01865 2.89e-272 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
CGEHFNKO_01866 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
CGEHFNKO_01867 6.32e-309 ywoD - - EGP - - - Major facilitator superfamily
CGEHFNKO_01868 1.61e-132 yjgF - - Q - - - Isochorismatase family
CGEHFNKO_01869 2.19e-290 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
CGEHFNKO_01870 1.29e-76 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
CGEHFNKO_01871 1.72e-266 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
CGEHFNKO_01872 5.79e-132 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
CGEHFNKO_01873 4.67e-95 ywnJ - - S - - - VanZ like family
CGEHFNKO_01874 1.31e-188 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
CGEHFNKO_01875 1.6e-114 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
CGEHFNKO_01877 1.04e-89 ywnF - - S - - - Family of unknown function (DUF5392)
CGEHFNKO_01878 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CGEHFNKO_01879 2.8e-79 ywnC - - S - - - Family of unknown function (DUF5362)
CGEHFNKO_01880 5.3e-157 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
CGEHFNKO_01881 2.18e-88 ywnA - - K - - - Transcriptional regulator
CGEHFNKO_01882 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
CGEHFNKO_01883 1.85e-82 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
CGEHFNKO_01884 2.86e-68 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
CGEHFNKO_01885 2.01e-16 csbD - - K - - - CsbD-like
CGEHFNKO_01886 8.64e-107 ywmF - - S - - - Peptidase M50
CGEHFNKO_01887 6.28e-116 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
CGEHFNKO_01888 1.31e-246 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CGEHFNKO_01889 7.14e-184 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CGEHFNKO_01891 8.69e-158 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
CGEHFNKO_01892 2.59e-160 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
CGEHFNKO_01893 3.47e-243 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
CGEHFNKO_01894 7.05e-306 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CGEHFNKO_01895 3.81e-171 ywmB - - S - - - TATA-box binding
CGEHFNKO_01896 2.17e-43 ywzB - - S - - - membrane
CGEHFNKO_01897 2.92e-117 ywmA - - - - - - -
CGEHFNKO_01898 8.24e-83 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
CGEHFNKO_01899 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CGEHFNKO_01900 1.1e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CGEHFNKO_01901 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CGEHFNKO_01902 1.95e-116 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CGEHFNKO_01903 1.66e-82 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CGEHFNKO_01904 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CGEHFNKO_01905 1.05e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
CGEHFNKO_01906 4.49e-80 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
CGEHFNKO_01907 2.24e-147 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CGEHFNKO_01908 1.7e-300 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CGEHFNKO_01909 3.68e-125 ywlG - - S - - - Belongs to the UPF0340 family
CGEHFNKO_01910 6.74e-106 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
CGEHFNKO_01911 2.08e-101 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CGEHFNKO_01912 1.66e-119 mntP - - P - - - Probably functions as a manganese efflux pump
CGEHFNKO_01913 1.08e-243 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
CGEHFNKO_01914 5.15e-100 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
CGEHFNKO_01915 6.57e-153 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
CGEHFNKO_01916 2.96e-79 ywlA - - S - - - Uncharacterised protein family (UPF0715)
CGEHFNKO_01918 9.87e-203 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
CGEHFNKO_01919 1.11e-244 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CGEHFNKO_01920 2.14e-87 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CGEHFNKO_01921 3.48e-122 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
CGEHFNKO_01922 2.02e-202 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
CGEHFNKO_01923 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
CGEHFNKO_01924 6.49e-135 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
CGEHFNKO_01925 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
CGEHFNKO_01926 5.13e-304 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CGEHFNKO_01927 1.43e-224 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
CGEHFNKO_01928 5.55e-304 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CGEHFNKO_01929 2.22e-144 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CGEHFNKO_01930 5.51e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
CGEHFNKO_01931 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
CGEHFNKO_01932 8.11e-121 ywjG - - S - - - Domain of unknown function (DUF2529)
CGEHFNKO_01933 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
CGEHFNKO_01934 6.53e-80 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
CGEHFNKO_01935 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
CGEHFNKO_01936 4.92e-285 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
CGEHFNKO_01937 6.65e-234 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
CGEHFNKO_01938 1.13e-58 ywjC - - - - - - -
CGEHFNKO_01939 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
CGEHFNKO_01940 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CGEHFNKO_01941 8.65e-136 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
CGEHFNKO_01942 1.45e-159 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
CGEHFNKO_01943 9.69e-128 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
CGEHFNKO_01944 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
CGEHFNKO_01945 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CGEHFNKO_01946 1.01e-109 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
CGEHFNKO_01947 1.51e-178 ywiC - - S - - - YwiC-like protein
CGEHFNKO_01948 3.82e-167 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
CGEHFNKO_01949 1.05e-273 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
CGEHFNKO_01950 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
CGEHFNKO_01951 6.59e-96 ywiB - - S - - - protein conserved in bacteria
CGEHFNKO_01952 1.49e-309 ywhL - - CO - - - amine dehydrogenase activity
CGEHFNKO_01953 4.77e-291 ywhK - - CO - - - amine dehydrogenase activity
CGEHFNKO_01954 5.77e-100 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
CGEHFNKO_01956 9.15e-41 ydcG - - K ko:K07729 - ko00000,ko03000 sequence-specific DNA binding
CGEHFNKO_01957 2.41e-45 - - - - - - - -
CGEHFNKO_01958 1.14e-36 - - - S - - - Domain of unknown function (DUF4177)
CGEHFNKO_01960 2.42e-100 - - - CP - - - Membrane
CGEHFNKO_01963 2.1e-215 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
CGEHFNKO_01964 1.58e-203 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CGEHFNKO_01965 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
CGEHFNKO_01966 4.45e-108 - - - - - - - -
CGEHFNKO_01967 3.32e-124 ywhD - - S - - - YwhD family
CGEHFNKO_01968 3.84e-153 ywhC - - S - - - Peptidase family M50
CGEHFNKO_01969 2.37e-34 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
CGEHFNKO_01970 1.02e-93 ywhA - - K - - - Transcriptional regulator
CGEHFNKO_01971 2.71e-316 potE5 - - E ko:K03294 - ko00000 C-terminus of AA_permease
CGEHFNKO_01972 2.02e-115 ywgA - - - ko:K09388 - ko00000 -
CGEHFNKO_01973 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
CGEHFNKO_01974 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
CGEHFNKO_01975 2.48e-145 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
CGEHFNKO_01976 1.08e-67 - - - K ko:K10947 - ko00000,ko03000 PadR family transcriptional regulator
CGEHFNKO_01977 3.23e-121 - - - S - - - membrane
CGEHFNKO_01978 3.32e-211 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
CGEHFNKO_01979 1.47e-215 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC transporter (permease)
CGEHFNKO_01982 1.16e-238 - - - - - - - -
CGEHFNKO_01984 9.14e-204 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
CGEHFNKO_01985 2.25e-210 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
CGEHFNKO_01986 1.97e-212 - - - S - - - Conserved hypothetical protein 698
CGEHFNKO_01987 1.67e-224 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
CGEHFNKO_01988 4.87e-187 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
CGEHFNKO_01989 2.94e-181 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
CGEHFNKO_01990 2.12e-295 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
CGEHFNKO_01991 8.14e-265 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
CGEHFNKO_01992 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
CGEHFNKO_01993 1.14e-180 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CGEHFNKO_01994 1.19e-176 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
CGEHFNKO_01995 5.69e-146 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
CGEHFNKO_01996 8.55e-288 ywfA - - EGP - - - -transporter
CGEHFNKO_01997 2.54e-267 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
CGEHFNKO_01998 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
CGEHFNKO_01999 0.0 rocB - - E - - - arginine degradation protein
CGEHFNKO_02000 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
CGEHFNKO_02001 6.34e-314 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
CGEHFNKO_02002 4.49e-77 - - - - - - - -
CGEHFNKO_02003 1.15e-112 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
CGEHFNKO_02004 3.34e-208 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
CGEHFNKO_02005 9.08e-234 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
CGEHFNKO_02006 1.63e-176 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CGEHFNKO_02007 2.06e-235 spsG - - M - - - Spore Coat
CGEHFNKO_02008 4.81e-172 spsF - - M ko:K07257 - ko00000 Spore Coat
CGEHFNKO_02009 1.01e-273 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
CGEHFNKO_02010 1.35e-205 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
CGEHFNKO_02011 1.52e-283 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
CGEHFNKO_02012 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
CGEHFNKO_02013 9.06e-184 spsA - - M - - - Spore Coat
CGEHFNKO_02014 1.49e-89 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
CGEHFNKO_02015 2.17e-76 ywdK - - S - - - small membrane protein
CGEHFNKO_02016 3.96e-293 ywdJ - - F - - - Xanthine uracil
CGEHFNKO_02017 1.24e-61 ywdI - - S - - - Family of unknown function (DUF5327)
CGEHFNKO_02018 5.93e-170 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CGEHFNKO_02019 2.42e-194 ywdF - - S - - - Glycosyltransferase like family 2
CGEHFNKO_02021 3.46e-116 ywdD - - - - - - -
CGEHFNKO_02022 1.6e-75 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
CGEHFNKO_02023 4.13e-187 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
CGEHFNKO_02024 3.52e-26 ywdA - - - - - - -
CGEHFNKO_02025 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
CGEHFNKO_02026 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
CGEHFNKO_02027 5.46e-195 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
CGEHFNKO_02029 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
CGEHFNKO_02030 1.1e-234 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CGEHFNKO_02031 1.14e-178 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
CGEHFNKO_02032 1.35e-264 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
CGEHFNKO_02033 1.37e-99 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
CGEHFNKO_02034 1.03e-50 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
CGEHFNKO_02035 1.6e-82 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
CGEHFNKO_02036 2.84e-143 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
CGEHFNKO_02037 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CGEHFNKO_02038 2.21e-228 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
CGEHFNKO_02039 5.74e-48 ydaS - - S - - - membrane
CGEHFNKO_02040 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
CGEHFNKO_02041 8.52e-288 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CGEHFNKO_02042 3.45e-81 gtcA - - S - - - GtrA-like protein
CGEHFNKO_02043 6.43e-146 - - - K - - - Bacterial regulatory proteins, tetR family
CGEHFNKO_02045 7.5e-168 - - - H - - - Methionine biosynthesis protein MetW
CGEHFNKO_02046 4.7e-170 - - - S - - - Streptomycin biosynthesis protein StrF
CGEHFNKO_02047 1.79e-144 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
CGEHFNKO_02048 3.78e-310 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
CGEHFNKO_02049 1.42e-146 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
CGEHFNKO_02050 1.52e-174 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CGEHFNKO_02051 4.83e-202 ywbI - - K - - - Transcriptional regulator
CGEHFNKO_02052 9.02e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
CGEHFNKO_02053 6.47e-144 ywbG - - M - - - effector of murein hydrolase
CGEHFNKO_02054 9.1e-38 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
CGEHFNKO_02055 6.09e-70 - - - L - - - COG2963 Transposase and inactivated derivatives
CGEHFNKO_02056 1.21e-178 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
CGEHFNKO_02057 5.45e-112 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
CGEHFNKO_02058 4.77e-217 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
CGEHFNKO_02059 1.2e-283 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
CGEHFNKO_02060 1.51e-87 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
CGEHFNKO_02061 3.28e-315 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CGEHFNKO_02062 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
CGEHFNKO_02063 6.04e-207 gspA - - M - - - General stress
CGEHFNKO_02064 4.35e-150 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
CGEHFNKO_02065 7.57e-215 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
CGEHFNKO_02066 7.08e-18 - - - S - - - D-Ala-teichoic acid biosynthesis protein
CGEHFNKO_02067 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CGEHFNKO_02068 2.56e-293 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
CGEHFNKO_02069 1.96e-49 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CGEHFNKO_02070 2.65e-290 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CGEHFNKO_02071 1.35e-261 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
CGEHFNKO_02072 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
CGEHFNKO_02073 1.18e-67 licA 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
CGEHFNKO_02074 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CGEHFNKO_02075 4.46e-66 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
CGEHFNKO_02076 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
CGEHFNKO_02077 1.26e-142 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
CGEHFNKO_02078 1.15e-220 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGEHFNKO_02079 4.83e-231 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGEHFNKO_02080 5.34e-213 cbrA3 - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
CGEHFNKO_02081 3.71e-76 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
CGEHFNKO_02082 1.55e-291 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CGEHFNKO_02083 1.18e-66 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
CGEHFNKO_02084 4.57e-65 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
CGEHFNKO_02085 7.31e-305 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CGEHFNKO_02086 0.0 ydhP 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
CGEHFNKO_02087 3.77e-215 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
CGEHFNKO_02088 1.41e-241 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
CGEHFNKO_02089 1.31e-267 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
CGEHFNKO_02090 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
CGEHFNKO_02091 7.57e-244 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
CGEHFNKO_02092 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
CGEHFNKO_02093 1.07e-201 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CGEHFNKO_02094 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
CGEHFNKO_02095 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
CGEHFNKO_02096 9.56e-243 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
CGEHFNKO_02097 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
CGEHFNKO_02098 4.75e-289 cimH - - C - - - COG3493 Na citrate symporter
CGEHFNKO_02099 1.2e-200 yxkH - - G - - - Polysaccharide deacetylase
CGEHFNKO_02100 1.9e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
CGEHFNKO_02101 2.98e-214 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
CGEHFNKO_02102 4.82e-190 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
CGEHFNKO_02103 8.94e-119 yxkC - - S - - - Domain of unknown function (DUF4352)
CGEHFNKO_02104 2.19e-248 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
CGEHFNKO_02105 1.15e-300 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
CGEHFNKO_02108 7.42e-112 yxjI - - S - - - LURP-one-related
CGEHFNKO_02109 2.8e-278 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
CGEHFNKO_02110 1.16e-209 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
CGEHFNKO_02111 3.47e-268 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CGEHFNKO_02112 5.32e-126 - - - T - - - Domain of unknown function (DUF4163)
CGEHFNKO_02113 2.68e-67 yxiS - - - - - - -
CGEHFNKO_02114 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
CGEHFNKO_02115 1.91e-282 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
CGEHFNKO_02116 9.87e-186 bglS - - M - - - licheninase activity
CGEHFNKO_02117 2.81e-192 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
CGEHFNKO_02118 2.21e-283 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
CGEHFNKO_02119 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
CGEHFNKO_02121 1.21e-19 - - - - - - - -
CGEHFNKO_02127 3.75e-94 yxiG - - - - - - -
CGEHFNKO_02130 1.34e-257 pelB 4.2.2.10, 4.2.2.2 - G ko:K01728,ko:K01732 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
CGEHFNKO_02131 7.23e-209 yxxF - - EG - - - EamA-like transporter family
CGEHFNKO_02132 3.61e-96 yxiE - - T - - - Belongs to the universal stress protein A family
CGEHFNKO_02133 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
CGEHFNKO_02134 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
CGEHFNKO_02135 0.0 - - - L - - - HKD family nuclease
CGEHFNKO_02136 3.4e-85 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
CGEHFNKO_02137 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
CGEHFNKO_02138 2.45e-103 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
CGEHFNKO_02139 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
CGEHFNKO_02140 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CGEHFNKO_02141 5.73e-302 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
CGEHFNKO_02142 2.9e-226 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
CGEHFNKO_02143 0.0 hutM - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
CGEHFNKO_02144 3.85e-297 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
CGEHFNKO_02145 4.04e-265 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CGEHFNKO_02146 4.09e-145 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CGEHFNKO_02147 1e-220 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
CGEHFNKO_02148 2.32e-193 yxeH - - S - - - hydrolases of the HAD superfamily
CGEHFNKO_02151 2.06e-42 yxeE - - - - - - -
CGEHFNKO_02152 5.09e-35 yxeD - - - - - - -
CGEHFNKO_02153 2.8e-46 - - - - - - - -
CGEHFNKO_02154 8.69e-230 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
CGEHFNKO_02155 4.9e-76 yxeA - - S - - - Protein of unknown function (DUF1093)
CGEHFNKO_02156 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
CGEHFNKO_02157 3.28e-182 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
CGEHFNKO_02158 1.23e-227 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
CGEHFNKO_02159 5.65e-160 yxdJ - - T ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CGEHFNKO_02160 0.0 - - - T - - - Histidine kinase
CGEHFNKO_02161 1.91e-177 yvrH - - T - - - Transcriptional regulator
CGEHFNKO_02162 2.52e-209 - - - V ko:K20459,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
CGEHFNKO_02163 1.36e-167 - - - S ko:K20460 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 permease
CGEHFNKO_02164 1.89e-170 - - - S ko:K20461 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
CGEHFNKO_02165 3.45e-205 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
CGEHFNKO_02166 2.07e-201 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
CGEHFNKO_02167 1.08e-212 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
CGEHFNKO_02168 7.67e-252 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
CGEHFNKO_02169 3.15e-295 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
CGEHFNKO_02170 1.61e-223 iolE 4.2.1.44 - H ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
CGEHFNKO_02171 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
CGEHFNKO_02172 6.88e-232 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
CGEHFNKO_02173 3.59e-202 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
CGEHFNKO_02174 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
CGEHFNKO_02175 6.09e-175 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
CGEHFNKO_02176 1.43e-223 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
CGEHFNKO_02177 1.1e-313 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
CGEHFNKO_02178 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
CGEHFNKO_02180 5.9e-193 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
CGEHFNKO_02181 7.82e-134 desR - - T ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CGEHFNKO_02182 2.9e-255 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
CGEHFNKO_02183 3.84e-259 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
CGEHFNKO_02184 3.41e-278 yxbF - - K - - - Bacterial regulatory proteins, tetR family
CGEHFNKO_02185 8.41e-316 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
CGEHFNKO_02186 1.45e-190 yxaL - - S - - - PQQ-like domain
CGEHFNKO_02187 7.16e-85 - - - S - - - Family of unknown function (DUF5391)
CGEHFNKO_02188 1.21e-67 arsR3 - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
CGEHFNKO_02189 3.8e-256 - - - EGP - - - Major Facilitator Superfamily
CGEHFNKO_02190 9.49e-98 yxaI - - S - - - membrane protein domain
CGEHFNKO_02191 8.4e-166 - - - E - - - Ring-cleavage extradiol dioxygenase
CGEHFNKO_02192 1.93e-05 htpX3 - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 COG0501 Zn-dependent protease with chaperone function
CGEHFNKO_02193 1.46e-116 mrr2 - - V ko:K07448 - ko00000,ko02048 Mrr N-terminal domain
CGEHFNKO_02194 1.61e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
CGEHFNKO_02195 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
CGEHFNKO_02196 7.97e-292 - - - S - - - Fic/DOC family
CGEHFNKO_02197 5.26e-314 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
CGEHFNKO_02198 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
CGEHFNKO_02199 3.87e-111 pucE 1.2.5.3 - C ko:K03518 - ko00000,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
CGEHFNKO_02200 1.7e-200 - - - C - - - COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
CGEHFNKO_02201 0.0 - - - C - - - COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
CGEHFNKO_02202 2.35e-122 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
CGEHFNKO_02203 4.36e-239 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CGEHFNKO_02204 2.7e-221 - - - S - - - Fusaric acid resistance protein-like
CGEHFNKO_02205 2.06e-25 - - - - - - - -
CGEHFNKO_02206 5.82e-20 - - - K - - - Helix-turn-helix XRE-family like proteins
CGEHFNKO_02207 1.09e-138 yhdJ 2.1.1.72 - L ko:K00571,ko:K07319 - ko00000,ko01000,ko02048 Belongs to the N(4) N(6)-methyltransferase family
CGEHFNKO_02209 4.5e-100 - - - S - - - AIPR protein
CGEHFNKO_02210 1.01e-105 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CGEHFNKO_02215 3.57e-276 yycP - - - - - - -
CGEHFNKO_02216 2.9e-172 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
CGEHFNKO_02217 1.76e-232 - - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
CGEHFNKO_02218 3.98e-111 yycN - - K - - - Acetyltransferase
CGEHFNKO_02220 1.91e-261 - - - S ko:K06361,ko:K06365,ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
CGEHFNKO_02221 1.86e-212 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
CGEHFNKO_02222 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
CGEHFNKO_02223 6.81e-295 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
CGEHFNKO_02224 1.69e-83 yvaZ - - S - - - Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
CGEHFNKO_02225 2.69e-57 sdpR - - K - - - transcriptional
CGEHFNKO_02226 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
CGEHFNKO_02227 4.53e-189 - 1.14.11.27 - P ko:K10277 - ko00000,ko01000,ko03036 peptidyl-arginine hydroxylation
CGEHFNKO_02228 0.0 - - - S - - - ABC transporter
CGEHFNKO_02229 4.27e-257 - - - S - - - Major Facilitator Superfamily
CGEHFNKO_02230 0.0 - - - - - - - -
CGEHFNKO_02231 1.14e-243 thiF 2.7.7.73 - H ko:K03148 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 ThiF family
CGEHFNKO_02232 0.0 - 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
CGEHFNKO_02233 9.23e-14 phoP1 - - KT ko:K02483 - ko00000,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CGEHFNKO_02234 6.63e-278 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CGEHFNKO_02235 9.84e-192 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
CGEHFNKO_02236 1.45e-196 yycI - - S - - - protein conserved in bacteria
CGEHFNKO_02237 0.0 yycH - - S - - - protein conserved in bacteria
CGEHFNKO_02238 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
CGEHFNKO_02239 1.51e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CGEHFNKO_02244 1.06e-315 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CGEHFNKO_02245 2.82e-97 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CGEHFNKO_02246 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
CGEHFNKO_02247 1.09e-38 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
CGEHFNKO_02250 5.12e-25 yycC - - K - - - YycC-like protein
CGEHFNKO_02251 6.26e-306 - - - M - - - Glycosyltransferase Family 4
CGEHFNKO_02252 8.1e-262 - - - S - - - Ecdysteroid kinase
CGEHFNKO_02253 3.96e-298 - - - S - - - Carbamoyl-phosphate synthase L chain, ATP binding domain
CGEHFNKO_02254 2.71e-298 - - - M - - - Glycosyltransferase Family 4
CGEHFNKO_02255 1.46e-155 - - - S - - - GlcNAc-PI de-N-acetylase
CGEHFNKO_02256 1.75e-116 - - - KLT - - - COG0515 Serine threonine protein kinase
CGEHFNKO_02257 1.58e-95 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
CGEHFNKO_02258 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
CGEHFNKO_02259 3.68e-206 yybS - - S - - - membrane
CGEHFNKO_02261 3.33e-111 cotF - - M ko:K06329 - ko00000 Spore coat protein
CGEHFNKO_02262 4.56e-87 yybR - - K - - - Transcriptional regulator
CGEHFNKO_02263 2.95e-211 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
CGEHFNKO_02264 3.4e-196 ypaH - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
CGEHFNKO_02265 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
CGEHFNKO_02266 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
CGEHFNKO_02267 2.4e-152 - - - K - - - FCD domain
CGEHFNKO_02268 1.36e-117 - - - S - - - PFAM DinB family protein
CGEHFNKO_02269 4.05e-205 - - - G - - - Major Facilitator Superfamily
CGEHFNKO_02270 5.19e-102 eamA1 - - EG - - - spore germination
CGEHFNKO_02272 6.22e-209 - - - K - - - LysR substrate binding domain
CGEHFNKO_02273 1.13e-129 - - - E - - - LysE type translocator
CGEHFNKO_02274 1.56e-277 yybF - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
CGEHFNKO_02275 3.08e-211 yybE - - K - - - Transcriptional regulator
CGEHFNKO_02276 1.6e-73 ypaA - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
CGEHFNKO_02277 1.7e-148 ydgI - - C - - - nitroreductase
CGEHFNKO_02278 4.78e-90 - - - K - - - Winged helix DNA-binding domain
CGEHFNKO_02279 2.99e-191 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
CGEHFNKO_02280 4.54e-100 yybA - - K - - - transcriptional
CGEHFNKO_02281 2.21e-99 yjcF - - S - - - Acetyltransferase (GNAT) domain
CGEHFNKO_02282 4.75e-211 - - - M - - - Domain of Unknown Function (DUF1259)
CGEHFNKO_02283 2.02e-88 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
CGEHFNKO_02284 6.24e-214 - - - K - - - Transcriptional regulator
CGEHFNKO_02285 2.16e-177 bdh 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
CGEHFNKO_02286 7.11e-311 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CGEHFNKO_02287 1.73e-164 - - - EG - - - EamA-like transporter family
CGEHFNKO_02288 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
CGEHFNKO_02289 5.97e-210 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
CGEHFNKO_02290 0.0 - - - G ko:K08369 - ko00000,ko02000 Sugar (and other) transporter
CGEHFNKO_02291 5.93e-89 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CGEHFNKO_02292 1.19e-232 ccpB - - K - - - Transcriptional regulator
CGEHFNKO_02293 6.64e-184 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
CGEHFNKO_02294 3.01e-131 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CGEHFNKO_02295 7.93e-140 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
CGEHFNKO_02296 1.11e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CGEHFNKO_02297 4.77e-99 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
CGEHFNKO_02298 2.9e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
CGEHFNKO_02299 5.42e-254 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
CGEHFNKO_02300 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CGEHFNKO_02301 1.82e-45 yyzM - - S - - - protein conserved in bacteria
CGEHFNKO_02302 1.67e-225 yyaD - - S - - - Membrane
CGEHFNKO_02303 4.72e-108 yhhY - - K - - - FR47-like protein
CGEHFNKO_02304 4.91e-144 yyaC - - S - - - Sporulation protein YyaC
CGEHFNKO_02305 1.23e-190 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
CGEHFNKO_02306 1.18e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
CGEHFNKO_02307 1.1e-193 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
CGEHFNKO_02308 2.29e-164 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
CGEHFNKO_02309 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
CGEHFNKO_02310 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CGEHFNKO_02311 6.6e-142 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
CGEHFNKO_02312 2.12e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CGEHFNKO_02313 1.99e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
CGEHFNKO_02315 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CGEHFNKO_02316 3.45e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
CGEHFNKO_02317 3.19e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
CGEHFNKO_02318 3.2e-264 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CGEHFNKO_02319 6.18e-52 yaaB - - S - - - Domain of unknown function (DUF370)
CGEHFNKO_02320 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CGEHFNKO_02321 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CGEHFNKO_02322 3.47e-62 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
CGEHFNKO_02325 2.83e-124 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
CGEHFNKO_02326 1.02e-275 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
CGEHFNKO_02327 1.96e-109 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
CGEHFNKO_02328 5.37e-107 yuaE - - S - - - DinB superfamily
CGEHFNKO_02329 6.79e-141 - - - S - - - MOSC domain
CGEHFNKO_02330 4.99e-290 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
CGEHFNKO_02331 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
CGEHFNKO_02332 3.51e-125 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
CGEHFNKO_02333 2.03e-122 yuaB - - - - - - -
CGEHFNKO_02334 1.76e-155 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
CGEHFNKO_02335 1.82e-191 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
CGEHFNKO_02336 1.75e-151 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
CGEHFNKO_02337 9e-72 - - - L - - - COG2963 Transposase and inactivated derivatives
CGEHFNKO_02338 2.42e-281 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CGEHFNKO_02339 5.51e-159 - - - G - - - Cupin
CGEHFNKO_02340 4.46e-12 yjcN - - - - - - -
CGEHFNKO_02344 5.66e-133 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Aspartate phosphatase response regulator
CGEHFNKO_02345 1.36e-15 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
CGEHFNKO_02346 4.26e-19 - - - - - - - -
CGEHFNKO_02349 3.79e-186 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
CGEHFNKO_02350 6.02e-252 yubA - - S - - - transporter activity
CGEHFNKO_02351 1.35e-237 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
CGEHFNKO_02352 6.95e-127 yraA 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 DJ-1/PfpI family
CGEHFNKO_02353 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
CGEHFNKO_02354 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
CGEHFNKO_02355 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
CGEHFNKO_02356 1.89e-315 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
CGEHFNKO_02357 1.05e-177 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
CGEHFNKO_02358 1.61e-55 - - - - - - - -
CGEHFNKO_02359 1.21e-243 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
CGEHFNKO_02360 9.38e-99 yugU - - S - - - Uncharacterised protein family UPF0047
CGEHFNKO_02361 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
CGEHFNKO_02362 2.31e-296 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
CGEHFNKO_02363 1.67e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
CGEHFNKO_02364 1.24e-22 - - - - - - - -
CGEHFNKO_02365 4.93e-35 mstX - - S - - - Membrane-integrating protein Mistic
CGEHFNKO_02366 4.84e-231 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
CGEHFNKO_02367 8.53e-95 yugN - - S - - - YugN-like family
CGEHFNKO_02369 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
CGEHFNKO_02371 1.95e-133 - - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
CGEHFNKO_02372 4.34e-152 ycaC - - Q - - - Isochorismatase family
CGEHFNKO_02373 3.92e-291 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
CGEHFNKO_02374 2e-287 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
CGEHFNKO_02375 3.14e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
CGEHFNKO_02376 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
CGEHFNKO_02377 1.68e-266 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
CGEHFNKO_02378 3.08e-108 alaR - - K - - - Transcriptional regulator
CGEHFNKO_02379 4.03e-200 yugF - - I - - - Hydrolase
CGEHFNKO_02380 1.73e-54 yugE - - S - - - Domain of unknown function (DUF1871)
CGEHFNKO_02381 3.32e-286 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
CGEHFNKO_02382 4.27e-291 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
CGEHFNKO_02383 2.4e-89 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
CGEHFNKO_02384 3.22e-152 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
CGEHFNKO_02385 3.19e-264 yuxJ - - EGP - - - Major facilitator superfamily
CGEHFNKO_02386 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
CGEHFNKO_02387 2.62e-95 yuxK - - S - - - protein conserved in bacteria
CGEHFNKO_02388 1.6e-101 yufK - - S - - - Family of unknown function (DUF5366)
CGEHFNKO_02389 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
CGEHFNKO_02390 5.63e-163 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
CGEHFNKO_02391 4.98e-250 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
CGEHFNKO_02392 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
CGEHFNKO_02393 5.48e-238 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
CGEHFNKO_02394 4.39e-218 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
CGEHFNKO_02396 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
CGEHFNKO_02397 5.39e-91 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
CGEHFNKO_02398 1.47e-67 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
CGEHFNKO_02399 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
CGEHFNKO_02400 6.08e-102 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
CGEHFNKO_02401 1.91e-52 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
CGEHFNKO_02402 4.2e-79 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
CGEHFNKO_02403 1.45e-85 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
CGEHFNKO_02404 8.07e-148 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CGEHFNKO_02405 2.41e-310 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
CGEHFNKO_02407 2.7e-76 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Belongs to the FPP GGPP synthase family
CGEHFNKO_02408 2.66e-11 - - - S - - - DegQ (SacQ) family
CGEHFNKO_02409 6.01e-67 yuzC - - - - - - -
CGEHFNKO_02410 6.86e-296 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
CGEHFNKO_02411 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CGEHFNKO_02412 8.02e-135 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
CGEHFNKO_02413 7.94e-90 yueI - - S - - - Protein of unknown function (DUF1694)
CGEHFNKO_02414 2.23e-50 yueH - - S - - - YueH-like protein
CGEHFNKO_02415 6.33e-46 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
CGEHFNKO_02416 5.37e-238 yueF - - S - - - transporter activity
CGEHFNKO_02417 1.98e-31 - - - S - - - Protein of unknown function (DUF2642)
CGEHFNKO_02418 1.57e-124 yueE - - S ko:K06950 - ko00000 phosphohydrolase
CGEHFNKO_02419 1.38e-167 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CGEHFNKO_02420 8.01e-102 yueC - - S - - - Family of unknown function (DUF5383)
CGEHFNKO_02421 0.0 yueB - - S - - - type VII secretion protein EsaA
CGEHFNKO_02422 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
CGEHFNKO_02423 1.38e-276 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
CGEHFNKO_02424 9.1e-54 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
CGEHFNKO_02425 2.36e-61 yukE - - S - - - Belongs to the WXG100 family
CGEHFNKO_02426 5.19e-292 yukF - - QT - - - Transcriptional regulator
CGEHFNKO_02427 5.7e-261 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
CGEHFNKO_02428 5.08e-170 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
CGEHFNKO_02429 1.91e-46 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
CGEHFNKO_02430 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CGEHFNKO_02431 2.37e-221 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
CGEHFNKO_02432 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
CGEHFNKO_02433 1.59e-285 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
CGEHFNKO_02434 1.49e-172 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
CGEHFNKO_02435 2.54e-211 eSD - - S ko:K07017 - ko00000 Putative esterase
CGEHFNKO_02436 1.32e-154 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
CGEHFNKO_02437 7.52e-131 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
CGEHFNKO_02438 2.01e-276 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
CGEHFNKO_02439 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CGEHFNKO_02440 4.11e-100 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
CGEHFNKO_02441 1.4e-152 yuiC - - S - - - protein conserved in bacteria
CGEHFNKO_02442 8.54e-46 yuiB - - S - - - Putative membrane protein
CGEHFNKO_02443 9.81e-300 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
CGEHFNKO_02444 1.03e-238 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
CGEHFNKO_02446 4.7e-237 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
CGEHFNKO_02447 5.68e-40 - - - - - - - -
CGEHFNKO_02448 7.21e-94 - - - CP - - - Membrane
CGEHFNKO_02449 1.18e-159 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
CGEHFNKO_02451 8.77e-43 - - - S - - - Bacteriocin class IId cyclical uberolysin-like
CGEHFNKO_02453 6.61e-119 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
CGEHFNKO_02454 9.01e-178 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
CGEHFNKO_02455 1.38e-82 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
CGEHFNKO_02456 1.59e-207 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CGEHFNKO_02457 1.49e-273 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CGEHFNKO_02458 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
CGEHFNKO_02459 1.2e-265 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
CGEHFNKO_02460 2.81e-74 yuzD - - S - - - protein conserved in bacteria
CGEHFNKO_02461 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
CGEHFNKO_02462 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
CGEHFNKO_02463 3.21e-215 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
CGEHFNKO_02464 9.76e-253 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CGEHFNKO_02465 1.43e-308 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
CGEHFNKO_02466 3.12e-250 yutH - - S - - - Spore coat protein
CGEHFNKO_02467 1.5e-109 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
CGEHFNKO_02468 5.03e-181 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
CGEHFNKO_02469 2.67e-96 yutE - - S - - - Protein of unknown function DUF86
CGEHFNKO_02470 3.71e-62 yutD - - S - - - protein conserved in bacteria
CGEHFNKO_02471 3.92e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CGEHFNKO_02472 1.37e-249 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
CGEHFNKO_02473 5.56e-167 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
CGEHFNKO_02474 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
CGEHFNKO_02475 3.01e-186 yunE - - S ko:K07090 - ko00000 membrane transporter protein
CGEHFNKO_02476 1.8e-217 yunF - - S - - - Protein of unknown function DUF72
CGEHFNKO_02477 1.29e-81 - - - S - - - phosphoglycolate phosphatase activity
CGEHFNKO_02478 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
CGEHFNKO_02479 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
CGEHFNKO_02480 3.49e-16 xkdF3 - - L - - - Putative phage serine protease XkdF
CGEHFNKO_02482 2.89e-272 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
CGEHFNKO_02483 2.08e-302 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
CGEHFNKO_02484 2.94e-300 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
CGEHFNKO_02485 2.37e-216 bsn - - L - - - Ribonuclease
CGEHFNKO_02486 1.58e-263 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
CGEHFNKO_02487 5.89e-173 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
CGEHFNKO_02488 1.07e-205 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
CGEHFNKO_02489 8.84e-210 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
CGEHFNKO_02490 5.26e-203 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
CGEHFNKO_02491 4.47e-314 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
CGEHFNKO_02492 3.87e-237 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
CGEHFNKO_02493 3.32e-212 - - - K - - - helix_turn_helix, mercury resistance
CGEHFNKO_02495 5.4e-95 - - - - - - - -
CGEHFNKO_02496 9.84e-28 - - - S - - - Sporulation delaying protein SdpA
CGEHFNKO_02498 5.74e-86 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
CGEHFNKO_02499 1.51e-258 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
CGEHFNKO_02500 1.36e-159 - - - Q - - - ubiE/COQ5 methyltransferase family
CGEHFNKO_02501 3.05e-104 yncE - - S - - - Protein of unknown function (DUF2691)
CGEHFNKO_02502 7.64e-192 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
CGEHFNKO_02503 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
CGEHFNKO_02504 8.89e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
CGEHFNKO_02505 1.56e-296 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CGEHFNKO_02506 8.67e-312 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
CGEHFNKO_02507 3.82e-183 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
CGEHFNKO_02508 8.85e-85 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CGEHFNKO_02509 4.46e-187 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
CGEHFNKO_02510 2.08e-138 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
CGEHFNKO_02511 3.71e-237 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CGEHFNKO_02512 1.29e-76 yusD - - S - - - SCP-2 sterol transfer family
CGEHFNKO_02513 1.64e-72 yusE - - CO - - - Thioredoxin
CGEHFNKO_02514 4.38e-82 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
CGEHFNKO_02515 3.1e-55 yusG - - S - - - Protein of unknown function (DUF2553)
CGEHFNKO_02516 4.16e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
CGEHFNKO_02517 7.13e-84 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
CGEHFNKO_02518 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
CGEHFNKO_02519 5.22e-276 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
CGEHFNKO_02520 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
CGEHFNKO_02521 2.54e-213 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
CGEHFNKO_02522 1.48e-263 yusP - - P - - - Major facilitator superfamily
CGEHFNKO_02523 3.2e-58 - - - - - - - -
CGEHFNKO_02524 4.46e-72 yusN - - M - - - Coat F domain
CGEHFNKO_02525 1.37e-91 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
CGEHFNKO_02526 0.0 yusP - - P - - - Major facilitator superfamily
CGEHFNKO_02527 2.07e-204 - - - K - - - Transcriptional regulator
CGEHFNKO_02528 1.29e-179 - 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
CGEHFNKO_02529 5.11e-242 apbA 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CGEHFNKO_02530 2.15e-52 yusU - - S - - - Protein of unknown function (DUF2573)
CGEHFNKO_02531 1.29e-192 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
CGEHFNKO_02532 6.54e-61 - - - S - - - YusW-like protein
CGEHFNKO_02533 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
CGEHFNKO_02534 1.15e-198 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
CGEHFNKO_02535 9.4e-105 dps2 - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
CGEHFNKO_02536 1.6e-306 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CGEHFNKO_02537 3.17e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CGEHFNKO_02538 0.0 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
CGEHFNKO_02539 4.63e-33 - - - - - - - -
CGEHFNKO_02540 1.8e-200 yuxN - - K - - - Transcriptional regulator
CGEHFNKO_02541 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
CGEHFNKO_02542 1.83e-33 - - - S - - - Protein of unknown function (DUF3970)
CGEHFNKO_02543 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
CGEHFNKO_02544 5.31e-245 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
CGEHFNKO_02545 3.33e-266 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
CGEHFNKO_02546 2.91e-139 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CGEHFNKO_02547 8.56e-248 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
CGEHFNKO_02548 1.73e-161 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
CGEHFNKO_02549 1.23e-193 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
CGEHFNKO_02550 9.74e-134 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
CGEHFNKO_02551 1.62e-68 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
CGEHFNKO_02552 1.43e-291 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
CGEHFNKO_02553 4.59e-133 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
CGEHFNKO_02554 7.62e-289 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
CGEHFNKO_02555 1.38e-231 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGEHFNKO_02556 4.53e-213 yvrC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
CGEHFNKO_02557 3.51e-180 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
CGEHFNKO_02558 3.11e-218 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
CGEHFNKO_02559 0.0 yvrG - - T - - - Histidine kinase
CGEHFNKO_02560 2.7e-172 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CGEHFNKO_02561 1.67e-50 - - - - - - - -
CGEHFNKO_02562 3.23e-134 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
CGEHFNKO_02563 1.88e-21 - - - S - - - YvrJ protein family
CGEHFNKO_02564 3.11e-295 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
CGEHFNKO_02565 8.03e-87 yvrL - - S - - - Regulatory protein YrvL
CGEHFNKO_02566 9.78e-189 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
CGEHFNKO_02567 9.64e-226 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGEHFNKO_02568 2.22e-236 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGEHFNKO_02569 2.21e-228 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
CGEHFNKO_02570 1.45e-158 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CGEHFNKO_02571 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
CGEHFNKO_02572 1.29e-20 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
CGEHFNKO_02573 1.01e-110 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
CGEHFNKO_02574 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
CGEHFNKO_02575 1.21e-214 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
CGEHFNKO_02576 4.78e-179 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
CGEHFNKO_02577 1.91e-125 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
CGEHFNKO_02578 1.06e-148 yfiK - - K - - - Regulator
CGEHFNKO_02579 2.12e-253 - - - T - - - Histidine kinase
CGEHFNKO_02580 1.42e-219 sagG - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
CGEHFNKO_02581 1e-248 sagH - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
CGEHFNKO_02582 2.52e-262 sagI - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
CGEHFNKO_02583 1.77e-200 yvgN - - S - - - reductase
CGEHFNKO_02584 9.69e-114 yvgO - - - - - - -
CGEHFNKO_02585 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
CGEHFNKO_02586 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
CGEHFNKO_02587 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CGEHFNKO_02588 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
CGEHFNKO_02589 1.82e-129 yvgT - - S - - - membrane
CGEHFNKO_02590 3.29e-191 - - - S - - - Metallo-peptidase family M12
CGEHFNKO_02591 4.33e-95 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
CGEHFNKO_02592 3.33e-140 bdbD - - O - - - Thioredoxin
CGEHFNKO_02593 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
CGEHFNKO_02594 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
CGEHFNKO_02595 3.24e-40 - - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Heavy-metal-associated domain
CGEHFNKO_02596 2.81e-64 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
CGEHFNKO_02597 3.5e-249 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
CGEHFNKO_02598 3.59e-154 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CGEHFNKO_02599 2.09e-207 - - - K - - - Helix-turn-helix XRE-family like proteins
CGEHFNKO_02600 2.93e-280 - - - EGP - - - Major Facilitator Superfamily
CGEHFNKO_02601 9.11e-92 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
CGEHFNKO_02602 4.15e-187 - - - S ko:K07045 - ko00000 Amidohydrolase
CGEHFNKO_02603 0.0 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CGEHFNKO_02604 7.12e-62 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
CGEHFNKO_02605 1.06e-233 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CGEHFNKO_02606 5.21e-180 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
CGEHFNKO_02607 3.35e-155 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
CGEHFNKO_02608 7.29e-157 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
CGEHFNKO_02609 1.83e-190 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
CGEHFNKO_02610 1.69e-167 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
CGEHFNKO_02611 3.16e-130 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
CGEHFNKO_02612 1.05e-207 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
CGEHFNKO_02613 3.94e-180 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
CGEHFNKO_02614 9.42e-63 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
CGEHFNKO_02616 1.83e-09 - - - - - - - -
CGEHFNKO_02619 1e-85 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 Ami_2
CGEHFNKO_02620 9.96e-80 - - - S - - - Pfam:Phage_holin_4_1
CGEHFNKO_02621 5.7e-14 - - - S - - - Phage uncharacterised protein (Phage_XkdX)
CGEHFNKO_02623 5.93e-218 - - - S - - - Domain of unknown function (DUF2479)
CGEHFNKO_02624 0.0 - - - M - - - Pectate lyase superfamily protein
CGEHFNKO_02625 1.12e-125 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
CGEHFNKO_02627 2.51e-171 - - - D - - - phage tail tape measure protein
CGEHFNKO_02628 2.37e-06 - - - - - - - -
CGEHFNKO_02629 4.79e-67 - - - S - - - phage major tail protein, phi13 family
CGEHFNKO_02630 2.12e-23 - - - - - - - -
CGEHFNKO_02631 5.04e-18 - - - S - - - TIGRFAM phage protein, HK97 gp10 family
CGEHFNKO_02633 4.73e-17 - - - S - - - Phage gp6-like head-tail connector protein
CGEHFNKO_02634 5.19e-120 - - - S - - - Phage capsid family
CGEHFNKO_02635 1.4e-61 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
CGEHFNKO_02636 3.66e-136 - - - S - - - Phage portal protein
CGEHFNKO_02637 4.66e-179 - - - S - - - Phage Terminase
CGEHFNKO_02639 4.31e-37 - - - L ko:K07451 - ko00000,ko01000,ko02048 HNH endonuclease
CGEHFNKO_02644 4.57e-94 - - - L - - - Phage integrase family
CGEHFNKO_02645 3.36e-69 - - - M - - - ArpU family transcriptional regulator
CGEHFNKO_02646 2.01e-07 - - - - - - - -
CGEHFNKO_02653 5.57e-66 - - - S - - - dUTPase
CGEHFNKO_02656 4.55e-21 yqaO - - S - - - Phage-like element PBSX protein XtrA
CGEHFNKO_02657 3.12e-05 - - - - - - - -
CGEHFNKO_02662 4.19e-45 pi346 - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
CGEHFNKO_02663 4.81e-108 - - - L - - - Conserved phage C-terminus (Phg_2220_C)
CGEHFNKO_02665 5e-05 - - - K - - - transcriptional
CGEHFNKO_02666 4.16e-08 - - - K - - - sequence-specific DNA binding
CGEHFNKO_02667 1.93e-49 - - - K - - - Helix-turn-helix XRE-family like proteins
CGEHFNKO_02669 1.74e-91 - - - - - - - -
CGEHFNKO_02670 1.36e-157 - - - S - - - Phage integrase family
CGEHFNKO_02672 4.85e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CGEHFNKO_02673 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
CGEHFNKO_02674 1.7e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
CGEHFNKO_02675 4.58e-36 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
CGEHFNKO_02676 1.64e-47 yvzC - - K - - - transcriptional
CGEHFNKO_02677 3.88e-92 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
CGEHFNKO_02678 3.52e-96 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
CGEHFNKO_02679 2.97e-70 yvaP - - K - - - transcriptional
CGEHFNKO_02680 0.0 spaK 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
CGEHFNKO_02681 4.69e-159 spaR - - K ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
CGEHFNKO_02682 1.96e-176 spaG - - S ko:K20492 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
CGEHFNKO_02683 1.41e-156 spaE - - S ko:K20491 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
CGEHFNKO_02684 1.33e-162 spaF - - V ko:K01990,ko:K20459,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
CGEHFNKO_02685 1.72e-143 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
CGEHFNKO_02686 1.13e-222 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
CGEHFNKO_02687 2.79e-145 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
CGEHFNKO_02688 1.17e-267 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
CGEHFNKO_02689 3.42e-124 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
CGEHFNKO_02690 2.64e-142 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
CGEHFNKO_02691 9.31e-222 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
CGEHFNKO_02692 1.61e-144 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
CGEHFNKO_02693 5.16e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
CGEHFNKO_02694 1.01e-129 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
CGEHFNKO_02695 7.67e-135 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
CGEHFNKO_02696 6.26e-156 yvbI - - M - - - Membrane
CGEHFNKO_02697 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
CGEHFNKO_02698 1.57e-106 yvbK - - K - - - acetyltransferase
CGEHFNKO_02699 4.64e-271 - - - EGP - - - Major facilitator Superfamily
CGEHFNKO_02700 2.69e-226 - - - - - - - -
CGEHFNKO_02701 6.37e-162 - - - S - - - GlcNAc-PI de-N-acetylase
CGEHFNKO_02702 2.89e-185 - - - C - - - WbqC-like protein family
CGEHFNKO_02703 4.57e-191 - - - M - - - Protein involved in cellulose biosynthesis
CGEHFNKO_02704 4.86e-297 - - - E - - - UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CGEHFNKO_02705 2.99e-220 arnA 4.2.1.46, 5.1.3.2 - M ko:K01710,ko:K01784 ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130 ko00000,ko00001,ko00002,ko01000 GDP-mannose 4,6 dehydratase
CGEHFNKO_02706 3.4e-278 - 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
CGEHFNKO_02707 0.0 - 1.1.1.136 - M ko:K13015 ko00520,map00520 ko00000,ko00001,ko01000,ko01005 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CGEHFNKO_02708 1.03e-304 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
CGEHFNKO_02709 9.69e-310 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
CGEHFNKO_02710 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
CGEHFNKO_02711 2.58e-177 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
CGEHFNKO_02712 3.98e-277 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
CGEHFNKO_02713 4.7e-237 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
CGEHFNKO_02714 2.95e-240 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
CGEHFNKO_02716 0.0 araE - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
CGEHFNKO_02717 3.86e-261 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
CGEHFNKO_02719 2.43e-241 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CGEHFNKO_02720 9.16e-162 yvbU - - K - - - Transcriptional regulator
CGEHFNKO_02721 1.82e-203 yvbV - - EG - - - EamA-like transporter family
CGEHFNKO_02722 6.69e-275 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
CGEHFNKO_02723 0.0 - - - - - - - -
CGEHFNKO_02724 2.23e-234 yhjM - - K - - - Transcriptional regulator
CGEHFNKO_02725 8.98e-149 - - - S ko:K07149 - ko00000 Membrane
CGEHFNKO_02726 1.79e-214 - 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
CGEHFNKO_02727 6.61e-196 gntR - - K - - - RpiR family transcriptional regulator
CGEHFNKO_02728 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
CGEHFNKO_02729 1.37e-290 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
CGEHFNKO_02731 6.42e-37 - - - M - - - nucleic acid phosphodiester bond hydrolysis
CGEHFNKO_02732 2.91e-172 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
CGEHFNKO_02733 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
CGEHFNKO_02734 6.14e-173 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
CGEHFNKO_02735 3.89e-285 - - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CGEHFNKO_02736 7.62e-157 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
CGEHFNKO_02737 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
CGEHFNKO_02738 2.39e-311 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
CGEHFNKO_02739 4.01e-44 yvfG - - S - - - YvfG protein
CGEHFNKO_02740 1.41e-240 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
CGEHFNKO_02741 2.72e-282 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
CGEHFNKO_02742 7.66e-77 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
CGEHFNKO_02743 3.32e-141 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
CGEHFNKO_02744 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CGEHFNKO_02745 1.22e-248 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
CGEHFNKO_02746 3.3e-260 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
CGEHFNKO_02747 2.28e-249 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
CGEHFNKO_02748 1.71e-262 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
CGEHFNKO_02749 4.98e-272 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
CGEHFNKO_02750 2.74e-206 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
CGEHFNKO_02751 1.23e-277 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
CGEHFNKO_02752 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
CGEHFNKO_02753 7.67e-152 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
CGEHFNKO_02754 4.08e-156 epsA - - M ko:K19420 - ko00000 biosynthesis protein
CGEHFNKO_02755 6.96e-100 - - - K ko:K19417 - ko00000,ko03000 transcriptional
CGEHFNKO_02756 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
CGEHFNKO_02758 1.57e-124 ywjB - - H - - - RibD C-terminal domain
CGEHFNKO_02759 1.45e-143 yyaS - - S ko:K07149 - ko00000 Membrane
CGEHFNKO_02760 1.15e-120 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CGEHFNKO_02761 2.47e-121 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
CGEHFNKO_02763 2.44e-50 - - - S - - - Protein of unknown function (DUF1433)
CGEHFNKO_02764 2.8e-16 - - - S - - - Protein of unknown function (DUF1433)
CGEHFNKO_02765 0.0 - - - I - - - Pfam Lipase (class 3)
CGEHFNKO_02766 4.44e-62 - - - - - - - -
CGEHFNKO_02767 4.38e-119 yybG - - S - - - Pentapeptide repeats (8 copies)
CGEHFNKO_02768 1.8e-27 - - - L - - - Phage integrase family
CGEHFNKO_02770 0.0 cscA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
CGEHFNKO_02771 1.35e-283 rafB - - P ko:K02532 - ko00000,ko02000 LacY proton/sugar symporter
CGEHFNKO_02772 9.47e-236 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
CGEHFNKO_02773 3.74e-136 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
CGEHFNKO_02774 1.22e-119 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
CGEHFNKO_02775 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
CGEHFNKO_02776 0.0 yvdK 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
CGEHFNKO_02777 1.19e-134 malA - - S - - - Protein of unknown function (DUF1189)
CGEHFNKO_02778 1.3e-178 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
CGEHFNKO_02779 2.21e-279 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
CGEHFNKO_02780 9.41e-265 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
CGEHFNKO_02781 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, N-terminal ig-like domain
CGEHFNKO_02782 6.6e-207 yvdE - - K - - - Transcriptional regulator
CGEHFNKO_02783 8.57e-134 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
CGEHFNKO_02784 1.3e-69 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
CGEHFNKO_02785 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
CGEHFNKO_02786 4.41e-137 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
CGEHFNKO_02787 2.06e-233 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CGEHFNKO_02788 2.26e-104 - - - M - - - Ribonuclease
CGEHFNKO_02789 2.82e-183 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
CGEHFNKO_02790 2.66e-48 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
CGEHFNKO_02791 5.16e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
CGEHFNKO_02792 8.99e-226 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
CGEHFNKO_02793 2.09e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
CGEHFNKO_02794 7.32e-113 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
CGEHFNKO_02795 3.13e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
CGEHFNKO_02796 7.1e-202 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
CGEHFNKO_02797 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
CGEHFNKO_02798 3.35e-246 sasA - - T - - - Histidine kinase
CGEHFNKO_02799 2.31e-157 mprA3 - - T - - - COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CGEHFNKO_02800 5.31e-73 - - - - - - - -
CGEHFNKO_02801 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
CGEHFNKO_02802 1.64e-143 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
CGEHFNKO_02803 9.74e-177 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
CGEHFNKO_02804 1.32e-166 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CGEHFNKO_02805 8.08e-147 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CGEHFNKO_02806 2.26e-135 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
CGEHFNKO_02807 2.72e-299 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CGEHFNKO_02808 1.83e-148 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
CGEHFNKO_02809 6.03e-270 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CGEHFNKO_02810 2.06e-177 yvpB - - NU - - - protein conserved in bacteria
CGEHFNKO_02811 1.07e-115 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
CGEHFNKO_02812 4.7e-157 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
CGEHFNKO_02813 1.45e-192 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CGEHFNKO_02814 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CGEHFNKO_02815 1.36e-285 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
CGEHFNKO_02816 1.9e-173 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
CGEHFNKO_02817 1.05e-171 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
CGEHFNKO_02818 5.16e-135 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
CGEHFNKO_02819 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
CGEHFNKO_02820 7.66e-66 yvlD - - S ko:K08972 - ko00000 Membrane
CGEHFNKO_02821 4.01e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
CGEHFNKO_02822 5.54e-219 yvlB - - S - - - Putative adhesin
CGEHFNKO_02823 6.92e-66 yvlA - - - - - - -
CGEHFNKO_02824 8.07e-44 yvkN - - - - - - -
CGEHFNKO_02825 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
CGEHFNKO_02826 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
CGEHFNKO_02827 2.59e-45 csbA - - S - - - protein conserved in bacteria
CGEHFNKO_02828 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
CGEHFNKO_02829 2.71e-143 yvkB - - K - - - Transcriptional regulator
CGEHFNKO_02830 8.4e-298 yvkA - - P - - - -transporter
CGEHFNKO_02831 5.03e-61 - - - Q - - - Thioesterase domain
CGEHFNKO_02832 8.73e-233 - - - S - - - Psort location CytoplasmicMembrane, score
CGEHFNKO_02833 4.68e-58 - - - E - - - Saccharopine dehydrogenase
CGEHFNKO_02834 1.05e-116 - - - V - - - ABC transporter transmembrane region
CGEHFNKO_02835 2.62e-282 nrpS2 - - Q - - - Non-ribosomal peptide synthetase modules and related proteins
CGEHFNKO_02836 1.65e-39 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
CGEHFNKO_02837 1.29e-280 glcP1 - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
CGEHFNKO_02838 5.18e-313 gabT 2.6.1.19 - E ko:K00823 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CGEHFNKO_02839 5.45e-231 suhB 3.1.3.25, 3.1.3.7 - G ko:K01082,ko:K01092 ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070 ko00000,ko00001,ko00002,ko01000,ko03016 inositol monophosphate 1-phosphatase activity
CGEHFNKO_02840 6.88e-257 - 1.1.1.14, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00008 ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
CGEHFNKO_02841 4.74e-289 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
CGEHFNKO_02842 1.54e-222 ybaS - - S - - - Na -dependent transporter
CGEHFNKO_02843 4.23e-147 ybbA - - S ko:K07017 - ko00000 Putative esterase
CGEHFNKO_02844 1.43e-229 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGEHFNKO_02845 2.19e-226 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGEHFNKO_02846 2.98e-220 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
CGEHFNKO_02847 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
CGEHFNKO_02848 1.92e-301 ybbC - - S - - - protein conserved in bacteria
CGEHFNKO_02849 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
CGEHFNKO_02850 2.29e-311 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
CGEHFNKO_02851 5.73e-301 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
CGEHFNKO_02852 1.34e-207 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CGEHFNKO_02853 6.11e-111 ybbJ - - J - - - acetyltransferase
CGEHFNKO_02854 1.36e-101 ybbK - - S - - - Protein of unknown function (DUF523)
CGEHFNKO_02860 4.59e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
CGEHFNKO_02861 1.11e-151 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
CGEHFNKO_02862 9e-188 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CGEHFNKO_02863 3.4e-289 ybbR - - S - - - protein conserved in bacteria
CGEHFNKO_02864 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CGEHFNKO_02865 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
CGEHFNKO_02866 5.45e-201 - - - - - - - -
CGEHFNKO_02867 1.36e-78 - - - S - - - Bacteriophage abortive infection AbiH
CGEHFNKO_02868 1.46e-27 - - - - - - - -
CGEHFNKO_02869 4.31e-199 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
CGEHFNKO_02870 4.76e-137 - - - S - - - ABC-2 family transporter protein
CGEHFNKO_02871 9.92e-126 ybdN - - - - - - -
CGEHFNKO_02872 1.5e-165 ybdO - - S - - - Domain of unknown function (DUF4885)
CGEHFNKO_02873 1.79e-207 dkgB - - S - - - Aldo/keto reductase family
CGEHFNKO_02874 7.37e-136 yxaC - - M - - - effector of murein hydrolase
CGEHFNKO_02875 1.41e-67 - - - S ko:K06518 - ko00000,ko02000 LrgA family
CGEHFNKO_02876 1.43e-95 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
CGEHFNKO_02877 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
CGEHFNKO_02878 1.29e-116 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
CGEHFNKO_02879 2.02e-131 - - - T - - - Histidine kinase
CGEHFNKO_02880 3.54e-104 - - - KT - - - helix_turn_helix, Lux Regulon
CGEHFNKO_02881 9.14e-172 yfiL - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
CGEHFNKO_02882 4.3e-184 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
CGEHFNKO_02883 1.33e-154 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
CGEHFNKO_02884 1.62e-19 - - - - - - - -
CGEHFNKO_02885 7.95e-73 - - - Q - - - Thioesterase domain
CGEHFNKO_02886 0.0 - - - Q - - - Non-ribosomal peptide synthetase modules and related proteins
CGEHFNKO_02887 0.0 - - - Q - - - Non-ribosomal peptide synthetase modules and related proteins
CGEHFNKO_02888 5.47e-150 - 2.3.1.39 - I ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 PFAM Acyl transferase
CGEHFNKO_02889 0.0 - - - Q - - - Beta-ketoacyl synthase
CGEHFNKO_02890 0.0 - - - Q - - - Polyketide synthase modules and related proteins
CGEHFNKO_02891 7.24e-121 - - - Q - - - Flavin containing amine oxidoreductase
CGEHFNKO_02892 0.0 - - - Q - - - TIGRFAM amino acid adenylation domain
CGEHFNKO_02893 8.47e-51 - - - Q - - - Dimerisation domain
CGEHFNKO_02894 8.99e-104 - - - S - - - Domain of unknown function (DUF4879)
CGEHFNKO_02895 2.48e-52 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
CGEHFNKO_02896 6.73e-149 yqeB - - - - - - -
CGEHFNKO_02897 6.46e-54 ybyB - - - - - - -
CGEHFNKO_02898 0.0 ybeC - - E - - - amino acid
CGEHFNKO_02900 1.42e-60 - - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
CGEHFNKO_02902 5.14e-22 - - - S - - - Protein of unknown function (DUF2651)
CGEHFNKO_02903 7.01e-212 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
CGEHFNKO_02904 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
CGEHFNKO_02905 5.8e-23 - - - S - - - Protein of unknown function (DUF2651)
CGEHFNKO_02906 2.02e-267 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
CGEHFNKO_02908 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
CGEHFNKO_02909 8.55e-46 - - - - - - - -
CGEHFNKO_02910 1.69e-107 - - - K - - - Helix-turn-helix XRE-family like proteins
CGEHFNKO_02911 2.05e-255 ypjH - - C ko:K08317 - ko00000,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
CGEHFNKO_02912 9.69e-273 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CGEHFNKO_02913 1.56e-120 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CGEHFNKO_02914 4.26e-113 ybfM - - S - - - SNARE associated Golgi protein
CGEHFNKO_02915 1.24e-193 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
CGEHFNKO_02916 7.41e-56 ybfN - - - - - - -
CGEHFNKO_02917 5.76e-245 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
CGEHFNKO_02918 8.22e-272 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
CGEHFNKO_02919 4.13e-255 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
CGEHFNKO_02920 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
CGEHFNKO_02921 3.04e-232 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
CGEHFNKO_02922 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
CGEHFNKO_02923 1.11e-240 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
CGEHFNKO_02924 1.08e-279 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
CGEHFNKO_02925 1e-221 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
CGEHFNKO_02926 5.89e-36 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
CGEHFNKO_02927 4.28e-198 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CGEHFNKO_02928 8.46e-146 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
CGEHFNKO_02929 2.61e-236 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
CGEHFNKO_02930 1.14e-83 ydfP - - S ko:K15977 - ko00000 DoxX
CGEHFNKO_02931 1.32e-74 ydfQ - - CO - - - Thioredoxin
CGEHFNKO_02932 1.63e-82 ycbP - - S - - - Protein of unknown function (DUF2512)
CGEHFNKO_02933 8.67e-101 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
CGEHFNKO_02934 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
CGEHFNKO_02935 8.68e-36 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
CGEHFNKO_02936 7.04e-160 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CGEHFNKO_02937 5.93e-155 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CGEHFNKO_02938 6e-267 ycbU - - E - - - Selenocysteine lyase
CGEHFNKO_02939 5.62e-310 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
CGEHFNKO_02940 8.93e-130 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
CGEHFNKO_02941 4.82e-255 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
CGEHFNKO_02942 8.07e-148 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
CGEHFNKO_02943 1.68e-252 yccF - - K ko:K07039 - ko00000 SEC-C motif
CGEHFNKO_02944 8.89e-218 yccK - - C - - - Aldo keto reductase
CGEHFNKO_02945 2.38e-228 ycdA - - S - - - Domain of unknown function (DUF5105)
CGEHFNKO_02946 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
CGEHFNKO_02947 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
CGEHFNKO_02948 6.25e-122 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
CGEHFNKO_02949 2.01e-248 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
CGEHFNKO_02950 1.05e-179 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
CGEHFNKO_02951 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
CGEHFNKO_02952 2.11e-213 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
CGEHFNKO_02953 1.4e-170 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
CGEHFNKO_02954 7.99e-173 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
CGEHFNKO_02955 6.94e-237 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CGEHFNKO_02956 2.86e-140 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
CGEHFNKO_02957 3.63e-136 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
CGEHFNKO_02958 2.46e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
CGEHFNKO_02959 2.12e-178 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
CGEHFNKO_02960 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
CGEHFNKO_02961 1.17e-246 yceH - - P - - - Belongs to the TelA family
CGEHFNKO_02962 1.5e-275 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
CGEHFNKO_02963 7.71e-294 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
CGEHFNKO_02964 2.45e-185 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
CGEHFNKO_02965 7e-211 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
CGEHFNKO_02966 7.93e-271 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
CGEHFNKO_02967 3.27e-293 ycgA - - S - - - Membrane
CGEHFNKO_02968 3.78e-107 ycgB - - - - - - -
CGEHFNKO_02969 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
CGEHFNKO_02970 1.39e-229 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
CGEHFNKO_02971 0.0 mdr - - EGP - - - the major facilitator superfamily
CGEHFNKO_02972 4.01e-100 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
CGEHFNKO_02973 1.11e-147 ycgF - - E - - - Lysine exporter protein LysE YggA
CGEHFNKO_02974 2.07e-192 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
CGEHFNKO_02975 9.42e-314 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
CGEHFNKO_02976 3.22e-146 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
CGEHFNKO_02977 7.44e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
CGEHFNKO_02978 2.47e-07 - - - S - - - Bacillus cereus group antimicrobial protein
CGEHFNKO_02979 3.49e-175 - 4.2.1.118 - G ko:K15652 ko00400,ko01110,ko01130,map00400,map01110,map01130 ko00000,ko00001,ko01000 Xylose isomerase-like TIM barrel
CGEHFNKO_02980 6.75e-304 - - - G ko:K08191,ko:K08194 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
CGEHFNKO_02981 8.64e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CGEHFNKO_02982 3.29e-233 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
CGEHFNKO_02983 9.1e-191 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
CGEHFNKO_02984 2.75e-216 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
CGEHFNKO_02985 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
CGEHFNKO_02986 2.21e-311 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CGEHFNKO_02987 5.81e-290 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
CGEHFNKO_02988 4.73e-242 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
CGEHFNKO_02989 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
CGEHFNKO_02990 8.45e-75 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
CGEHFNKO_02991 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CGEHFNKO_02992 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CGEHFNKO_02993 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
CGEHFNKO_02994 2.85e-285 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
CGEHFNKO_02995 4.96e-290 yciC - - S - - - GTPases (G3E family)
CGEHFNKO_02996 7.48e-283 fdh 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
CGEHFNKO_02997 4.43e-95 yckC - - S - - - membrane
CGEHFNKO_02998 3.31e-68 - - - S - - - Protein of unknown function (DUF2680)
CGEHFNKO_02999 0.0 yckE 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
CGEHFNKO_03000 6.79e-91 nin - - S - - - Competence protein J (ComJ)
CGEHFNKO_03001 1.88e-101 nucA - - M - - - Deoxyribonuclease NucA/NucB
CGEHFNKO_03002 3.11e-124 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
CGEHFNKO_03003 3.01e-137 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
CGEHFNKO_03004 4.1e-84 hxlR - - K - - - transcriptional
CGEHFNKO_03005 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CGEHFNKO_03006 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CGEHFNKO_03007 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
CGEHFNKO_03008 3.56e-179 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
CGEHFNKO_03009 1.72e-315 - - - E - - - Aminotransferase class I and II
CGEHFNKO_03010 1.95e-85 - - - S - - - YcxB-like protein
CGEHFNKO_03012 1.93e-217 ycxC - - EG - - - EamA-like transporter family
CGEHFNKO_03013 5.72e-316 ycxD - - K - - - GntR family transcriptional regulator
CGEHFNKO_03014 3.18e-168 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
CGEHFNKO_03015 7.33e-143 yczE - - S ko:K07149 - ko00000 membrane
CGEHFNKO_03016 8.3e-171 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
CGEHFNKO_03017 1.01e-152 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
CGEHFNKO_03018 1.14e-186 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
CGEHFNKO_03019 9.88e-205 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
CGEHFNKO_03020 3.44e-130 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
CGEHFNKO_03021 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
CGEHFNKO_03022 2.83e-52 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
CGEHFNKO_03023 8.28e-101 yclD - - - - - - -
CGEHFNKO_03024 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
CGEHFNKO_03025 0.0 yclG - - M - - - Pectate lyase superfamily protein
CGEHFNKO_03027 0.0 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
CGEHFNKO_03028 1.25e-303 gerKC - - S ko:K06297 - ko00000 spore germination
CGEHFNKO_03029 2.65e-248 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
CGEHFNKO_03030 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CGEHFNKO_03031 4.43e-120 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CGEHFNKO_03032 4.46e-183 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
CGEHFNKO_03033 1.49e-148 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
CGEHFNKO_03034 3.24e-169 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
CGEHFNKO_03035 1.39e-276 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
CGEHFNKO_03036 0.0 yxeQ - - S - - - MmgE/PrpD family
CGEHFNKO_03037 1.56e-156 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
CGEHFNKO_03038 3.16e-303 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
CGEHFNKO_03039 6.14e-163 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CGEHFNKO_03040 0.0 yclK - - T - - - COG0642 Signal transduction histidine kinase
CGEHFNKO_03041 1.2e-99 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
CGEHFNKO_03043 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
CGEHFNKO_03044 3.85e-211 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGEHFNKO_03045 6.96e-213 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGEHFNKO_03046 1.88e-174 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
CGEHFNKO_03047 1.68e-224 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
CGEHFNKO_03048 8.77e-317 ycnB - - EGP - - - the major facilitator superfamily
CGEHFNKO_03049 3.67e-196 ycnC - - K - - - Transcriptional regulator
CGEHFNKO_03050 1.19e-175 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Nitroreductase family
CGEHFNKO_03051 1.97e-59 ycnE - - S - - - Monooxygenase
CGEHFNKO_03052 1.37e-70 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
CGEHFNKO_03053 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CGEHFNKO_03054 1.08e-287 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CGEHFNKO_03055 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
CGEHFNKO_03056 8.27e-191 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
CGEHFNKO_03057 1.19e-186 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CGEHFNKO_03058 5.88e-131 ycnI - - S - - - protein conserved in bacteria
CGEHFNKO_03059 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
CGEHFNKO_03060 4.26e-138 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
CGEHFNKO_03061 1.59e-71 - - - - - - - -
CGEHFNKO_03062 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
CGEHFNKO_03063 1.68e-94 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
CGEHFNKO_03064 3.32e-263 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
CGEHFNKO_03065 2.89e-87 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
CGEHFNKO_03067 4.66e-178 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
CGEHFNKO_03068 2.49e-180 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
CGEHFNKO_03069 7.62e-271 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
CGEHFNKO_03070 1.7e-192 ycsI - - S - - - Belongs to the D-glutamate cyclase family
CGEHFNKO_03071 4.86e-177 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
CGEHFNKO_03072 7.27e-242 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
CGEHFNKO_03073 2.81e-168 kipR - - K - - - Transcriptional regulator
CGEHFNKO_03074 5.71e-152 ycsK - - E - - - anatomical structure formation involved in morphogenesis
CGEHFNKO_03076 5.95e-75 yczJ - - S - - - biosynthesis
CGEHFNKO_03077 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
CGEHFNKO_03078 6.31e-222 ycsN - - S - - - Oxidoreductase
CGEHFNKO_03079 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
CGEHFNKO_03080 0.0 ydaB - - IQ - - - acyl-CoA ligase
CGEHFNKO_03081 3.82e-207 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CGEHFNKO_03082 2.65e-123 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
CGEHFNKO_03083 1.35e-147 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
CGEHFNKO_03084 7.45e-101 ydaG - - S - - - general stress protein
CGEHFNKO_03085 5.35e-178 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
CGEHFNKO_03086 6.54e-63 ydzA - - EGP - - - Domain of unknown function (DUF3817)
CGEHFNKO_03087 7.97e-98 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
CGEHFNKO_03088 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CGEHFNKO_03089 8.41e-260 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
CGEHFNKO_03090 4.62e-190 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
CGEHFNKO_03091 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
CGEHFNKO_03092 1.85e-302 ydaM - - M - - - Glycosyl transferase family group 2
CGEHFNKO_03093 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
CGEHFNKO_03094 0.0 ydaO - - E - - - amino acid
CGEHFNKO_03095 3.21e-99 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
CGEHFNKO_03096 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
CGEHFNKO_03097 6.75e-76 - - - K - - - acetyltransferase
CGEHFNKO_03098 1.28e-45 - - - - - - - -
CGEHFNKO_03100 1.87e-48 xkdQ - - G - - - NLP P60 protein
CGEHFNKO_03101 1.25e-45 xkdR - - S - - - Protein of unknown function (DUF2577)
CGEHFNKO_03102 7.69e-139 racD 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
CGEHFNKO_03103 9.15e-17 xkdS - - S - - - Protein of unknown function (DUF2634)
CGEHFNKO_03104 1.49e-26 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
CGEHFNKO_03106 2.53e-114 - - - - - - - -
CGEHFNKO_03107 1.04e-130 - - - - - - - -
CGEHFNKO_03108 2.14e-53 - - - - - - - -
CGEHFNKO_03109 2.28e-289 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
CGEHFNKO_03111 1.95e-45 ydaT - - - - - - -
CGEHFNKO_03112 5.53e-96 yvaD - - S - - - Family of unknown function (DUF5360)
CGEHFNKO_03113 7.05e-72 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
CGEHFNKO_03114 5.39e-182 ydbA - - P - - - EcsC protein family
CGEHFNKO_03115 2.34e-10 gsiB - - S ko:K06884 - ko00000 general stress protein
CGEHFNKO_03116 1.53e-77 ydbB - - G - - - Cupin domain
CGEHFNKO_03117 1.28e-82 ydbC - - S - - - Domain of unknown function (DUF4937
CGEHFNKO_03118 1.51e-195 ydbD - - P ko:K07217 - ko00000 Catalase
CGEHFNKO_03119 4.46e-254 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
CGEHFNKO_03120 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
CGEHFNKO_03121 4.29e-152 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
CGEHFNKO_03122 3.91e-287 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
CGEHFNKO_03123 8.61e-231 ydbI - - S - - - AI-2E family transporter
CGEHFNKO_03124 1.67e-221 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
CGEHFNKO_03125 2.44e-167 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
CGEHFNKO_03126 6.56e-70 ydbL - - - - - - -
CGEHFNKO_03127 3.88e-264 ydbM - - I - - - acyl-CoA dehydrogenase
CGEHFNKO_03128 1.13e-15 - - - S - - - Fur-regulated basic protein B
CGEHFNKO_03129 4.63e-14 - - - S - - - Fur-regulated basic protein A
CGEHFNKO_03130 2.84e-160 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CGEHFNKO_03131 2.25e-74 ydbP - - CO - - - Thioredoxin
CGEHFNKO_03132 5.31e-259 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
CGEHFNKO_03133 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
CGEHFNKO_03134 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
CGEHFNKO_03135 2.18e-96 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
CGEHFNKO_03136 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
CGEHFNKO_03137 2.08e-138 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
CGEHFNKO_03138 1.37e-78 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
CGEHFNKO_03139 1.57e-235 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
CGEHFNKO_03140 9.41e-278 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CGEHFNKO_03141 6.68e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
CGEHFNKO_03142 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
CGEHFNKO_03143 1.05e-186 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
CGEHFNKO_03144 6.28e-75 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
CGEHFNKO_03145 1.73e-89 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
CGEHFNKO_03146 2.17e-242 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
CGEHFNKO_03147 9.77e-71 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
CGEHFNKO_03148 5.84e-110 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
CGEHFNKO_03149 1.14e-180 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CGEHFNKO_03150 5.75e-141 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
CGEHFNKO_03151 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
CGEHFNKO_03152 1.78e-21 - - - - - - - -
CGEHFNKO_03153 3.01e-76 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
CGEHFNKO_03162 1.2e-37 - - - S - - - Doxx family
CGEHFNKO_03163 1.76e-101 - - - K - - - Transcriptional regulator
CGEHFNKO_03164 7.94e-126 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CGEHFNKO_03165 7.85e-130 - - - GM - - - 3-beta hydroxysteroid dehydrogenase/isomerase family
CGEHFNKO_03166 1.08e-69 azoR - - I ko:K01118 - ko00000,ko01000 NADPH-dependent FMN reductase
CGEHFNKO_03167 1.91e-59 - - - K - - - Acetyltransferase (GNAT) domain
CGEHFNKO_03168 4.99e-43 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
CGEHFNKO_03169 4.52e-123 yrkL - - S ko:K11748 - ko00000,ko02000 Flavodoxin-like fold
CGEHFNKO_03170 0.0 - - - EGP ko:K03761,ko:K03762 - ko00000,ko02000 Transporter
CGEHFNKO_03171 4.25e-65 ohrR - - K - - - Transcriptional regulator
CGEHFNKO_03172 1.29e-90 yddJ - - S - - - Domain of unknown function with cystatin-like fold (DUF4467)
CGEHFNKO_03173 4.48e-98 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
CGEHFNKO_03174 1.59e-85 - - - S - - - YjbR
CGEHFNKO_03175 3.48e-98 ywnA - - K - - - Transcriptional regulator
CGEHFNKO_03176 3.84e-145 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
CGEHFNKO_03177 2.36e-245 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
CGEHFNKO_03178 2.24e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
CGEHFNKO_03179 4.87e-101 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
CGEHFNKO_03180 1.06e-154 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
CGEHFNKO_03181 5.18e-134 - - - S - - - Protein of unknown function (DUF2812)
CGEHFNKO_03182 8.2e-68 - - - K - - - Transcriptional regulator PadR-like family
CGEHFNKO_03183 6.16e-235 - - - S - - - Patatin-like phospholipase
CGEHFNKO_03184 8.34e-109 - - - S - - - DinB superfamily
CGEHFNKO_03185 3.65e-85 - - - G - - - Cupin domain
CGEHFNKO_03187 7.57e-216 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
CGEHFNKO_03188 4.29e-254 trkA - - P ko:K07222 - ko00000 Oxidoreductase
CGEHFNKO_03190 1.4e-191 dapA7 4.3.3.7 - EM ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Dihydrodipicolinate synthetase family
CGEHFNKO_03192 2.49e-255 cfr 2.1.1.224 - J ko:K15632 - ko00000,ko01000,ko01504,ko03009 Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
CGEHFNKO_03193 1.51e-73 ydeH - - - - - - -
CGEHFNKO_03194 2.61e-110 - - - F - - - nucleoside 2-deoxyribosyltransferase
CGEHFNKO_03195 5.37e-248 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CGEHFNKO_03196 9.13e-191 - - - Q - - - ubiE/COQ5 methyltransferase family
CGEHFNKO_03197 6.38e-192 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7 - H ko:K00941,ko:K14153 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
CGEHFNKO_03198 2.41e-298 - - - G - - - Haloacid dehalogenase-like hydrolase
CGEHFNKO_03199 1.7e-211 - - - S - - - Sodium Bile acid symporter family
CGEHFNKO_03200 1.44e-150 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
CGEHFNKO_03201 4.28e-68 - - - L - - - transposase activity
CGEHFNKO_03202 5.46e-259 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
CGEHFNKO_03203 7.29e-87 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
CGEHFNKO_03204 6.92e-282 nhaC_1 - - C - - - antiporter
CGEHFNKO_03205 0.0 - - - K ko:K00375 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
CGEHFNKO_03206 1.71e-145 paiB - - K ko:K07734 - ko00000,ko03000 Transcriptional regulator
CGEHFNKO_03208 3.57e-249 ydeR - - EGP - - - Uncharacterised MFS-type transporter YbfB
CGEHFNKO_03209 2.43e-132 ydeS - - K - - - Transcriptional regulator
CGEHFNKO_03210 7.47e-202 ydeK - - EG - - - -transporter
CGEHFNKO_03211 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CGEHFNKO_03212 5.09e-66 yraD - - M ko:K06439 - ko00000 Spore coat protein
CGEHFNKO_03213 2.92e-34 yraE - - - ko:K06440 - ko00000 -
CGEHFNKO_03214 5.05e-281 adhB 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
CGEHFNKO_03215 4.76e-84 yraF - - M - - - Spore coat protein
CGEHFNKO_03216 1.2e-49 yraG - - - ko:K06440 - ko00000 -
CGEHFNKO_03217 2.09e-276 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
CGEHFNKO_03218 1.98e-142 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CGEHFNKO_03219 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
CGEHFNKO_03220 8.37e-172 puuD - - S ko:K07010 - ko00000,ko01002 Peptidase C26
CGEHFNKO_03221 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
CGEHFNKO_03222 3.71e-127 ynaD - - J - - - Acetyltransferase (GNAT) domain
CGEHFNKO_03223 3.51e-191 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
CGEHFNKO_03224 2.03e-250 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
CGEHFNKO_03225 3.9e-268 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
CGEHFNKO_03226 1.37e-288 fabF_1 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
CGEHFNKO_03227 1.84e-199 - - - K - - - Helix-turn-helix XRE-family like proteins
CGEHFNKO_03228 9e-158 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
CGEHFNKO_03229 3.58e-107 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
CGEHFNKO_03230 6.15e-195 bltR - - K - - - helix_turn_helix, mercury resistance
CGEHFNKO_03231 8.93e-192 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
CGEHFNKO_03232 1.58e-145 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
CGEHFNKO_03233 4.68e-188 - - - Q - - - ubiE/COQ5 methyltransferase family
CGEHFNKO_03234 1.4e-210 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
CGEHFNKO_03235 1.32e-153 ydhC - - K - - - FCD
CGEHFNKO_03236 1.94e-290 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
CGEHFNKO_03239 0.0 pbpE - - V - - - Beta-lactamase
CGEHFNKO_03241 1.44e-126 ydhK - - M - - - Protein of unknown function (DUF1541)
CGEHFNKO_03242 1.58e-247 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
CGEHFNKO_03243 7.17e-172 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
CGEHFNKO_03244 3.25e-154 - - - K ko:K05799 - ko00000,ko03000 FCD
CGEHFNKO_03245 1.01e-275 yycB1 - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
CGEHFNKO_03246 4.25e-65 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
CGEHFNKO_03247 4.48e-67 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
CGEHFNKO_03248 3.63e-136 yvdT_1 - - K - - - Transcriptional regulator
CGEHFNKO_03249 0.0 ybeC - - E - - - amino acid
CGEHFNKO_03250 4.41e-214 ydhU - - P ko:K07217 - ko00000 Catalase
CGEHFNKO_03251 2.06e-112 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
CGEHFNKO_03252 2.83e-237 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
CGEHFNKO_03253 0.0 iolT - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
CGEHFNKO_03257 2.02e-47 ydjO - - S - - - Cold-inducible protein YdjO
CGEHFNKO_03258 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
CGEHFNKO_03259 4.33e-315 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
CGEHFNKO_03260 7.15e-198 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CGEHFNKO_03261 2.79e-226 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
CGEHFNKO_03262 9.37e-276 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
CGEHFNKO_03263 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
CGEHFNKO_03264 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
CGEHFNKO_03265 8.06e-123 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
CGEHFNKO_03266 0.0 - - - S - - - Domain of unknown function (DUF4179)
CGEHFNKO_03267 1.23e-269 pbuG - - S ko:K06901 - ko00000,ko02000 permease
CGEHFNKO_03268 2.02e-173 yebC - - M - - - Membrane
CGEHFNKO_03270 1.48e-119 yebE - - S - - - UPF0316 protein
CGEHFNKO_03271 6.56e-40 yebG - - S - - - NETI protein
CGEHFNKO_03272 1.13e-108 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CGEHFNKO_03273 1.31e-286 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CGEHFNKO_03274 6.38e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CGEHFNKO_03275 4.13e-167 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
CGEHFNKO_03276 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CGEHFNKO_03277 1.15e-167 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CGEHFNKO_03278 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CGEHFNKO_03279 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CGEHFNKO_03280 5.33e-244 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
CGEHFNKO_03281 7.3e-137 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CGEHFNKO_03282 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
CGEHFNKO_03283 1.99e-298 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
CGEHFNKO_03284 4.18e-34 - - - S - - - Protein of unknown function (DUF2892)
CGEHFNKO_03285 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
CGEHFNKO_03286 7.32e-248 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
CGEHFNKO_03287 2.03e-67 yerC - - S - - - protein conserved in bacteria
CGEHFNKO_03288 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
CGEHFNKO_03289 3.88e-164 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
CGEHFNKO_03290 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
CGEHFNKO_03291 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CGEHFNKO_03292 2.74e-286 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
CGEHFNKO_03293 1.48e-247 yerI - - S - - - homoserine kinase type II (protein kinase fold)
CGEHFNKO_03294 1.18e-157 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
CGEHFNKO_03295 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CGEHFNKO_03296 1.81e-60 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CGEHFNKO_03297 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
CGEHFNKO_03298 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CGEHFNKO_03299 1.63e-199 yerO - - K - - - Transcriptional regulator
CGEHFNKO_03300 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CGEHFNKO_03301 4.95e-216 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
CGEHFNKO_03302 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CGEHFNKO_03303 1.66e-249 - - - L - - - AAA ATPase domain
CGEHFNKO_03304 4.78e-140 - - - L - - - AAA domain
CGEHFNKO_03305 2.96e-87 - - - - - - - -
CGEHFNKO_03307 6.9e-41 - - - S - - - Colicin immunity protein / pyocin immunity protein
CGEHFNKO_03309 2.16e-103 - - - S - - - Protein of unknown function, DUF600
CGEHFNKO_03310 8.7e-70 - - - S - - - Protein of unknown function, DUF600
CGEHFNKO_03311 1.82e-68 - - - S - - - Protein of unknown function, DUF600
CGEHFNKO_03312 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 nucleic acid phosphodiester bond hydrolysis
CGEHFNKO_03313 1.4e-22 - - - - - - - -
CGEHFNKO_03314 0.0 - - - S - - - Bacterial EndoU nuclease
CGEHFNKO_03315 4.91e-23 - - - - - - - -
CGEHFNKO_03316 3.12e-162 yeeN - - K - - - transcriptional regulatory protein
CGEHFNKO_03318 4.61e-61 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
CGEHFNKO_03319 9.4e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
CGEHFNKO_03320 1.48e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
CGEHFNKO_03321 5.06e-126 yesJ - - K - - - Acetyltransferase (GNAT) family
CGEHFNKO_03322 5.92e-05 - - - - - - - -
CGEHFNKO_03323 1.22e-154 yetF - - S - - - membrane
CGEHFNKO_03324 1.11e-72 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
CGEHFNKO_03325 1.32e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CGEHFNKO_03326 1.88e-198 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
CGEHFNKO_03327 1.34e-31 - - - S - - - Uncharacterized small protein (DUF2292)
CGEHFNKO_03328 8.7e-72 - - - H - - - riboflavin kinase activity
CGEHFNKO_03329 2.19e-136 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
CGEHFNKO_03332 1.41e-115 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
CGEHFNKO_03333 2.34e-262 yetM - - CH - - - FAD binding domain
CGEHFNKO_03334 1.38e-251 yetN - - S - - - Protein of unknown function (DUF3900)
CGEHFNKO_03335 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
CGEHFNKO_03337 1.67e-66 - - - K - - - Winged helix DNA-binding domain
CGEHFNKO_03338 1.53e-211 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
CGEHFNKO_03339 1.53e-161 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
CGEHFNKO_03340 3.36e-130 - - - S - - - protein homooligomerization
CGEHFNKO_03341 1.62e-166 - - - - - - - -
CGEHFNKO_03342 8.86e-244 - - - S - - - ATP diphosphatase activity
CGEHFNKO_03343 0.0 - - - S ko:K09136 - ko00000,ko03009 YcaO cyclodehydratase, ATP-ad Mg2+-binding
CGEHFNKO_03344 3.71e-194 - - - C - - - Nitroreductase family
CGEHFNKO_03345 6.83e-146 - - - S - - - CAAX protease self-immunity
CGEHFNKO_03346 2.2e-186 - 2.1.1.163, 2.1.1.201 - Q ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 methyltransferase
CGEHFNKO_03348 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
CGEHFNKO_03349 1.77e-189 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
CGEHFNKO_03350 6.8e-220 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
CGEHFNKO_03351 2.31e-230 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
CGEHFNKO_03352 7.24e-285 yfnE - - S - - - Glycosyltransferase like family 2
CGEHFNKO_03353 2.43e-239 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
CGEHFNKO_03354 2.7e-278 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
CGEHFNKO_03355 2.93e-313 yfnA - - E ko:K03294 - ko00000 amino acid
CGEHFNKO_03356 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
CGEHFNKO_03357 5.01e-163 yfmS - - NT - - - chemotaxis protein
CGEHFNKO_03358 1.21e-214 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
CGEHFNKO_03359 3.6e-267 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
CGEHFNKO_03360 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
CGEHFNKO_03361 3.03e-91 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
CGEHFNKO_03362 1.25e-264 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
CGEHFNKO_03363 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
CGEHFNKO_03364 2.53e-264 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
CGEHFNKO_03365 9.83e-85 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
CGEHFNKO_03366 9.91e-241 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
CGEHFNKO_03367 4.44e-31 - - - S - - - Protein of unknown function (DUF3212)
CGEHFNKO_03368 4.9e-76 yflT - - S - - - Heat induced stress protein YflT
CGEHFNKO_03369 2.37e-310 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
CGEHFNKO_03370 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
CGEHFNKO_03372 1.03e-46 M1-820 - - Q - - - Collagen triple helix repeat (20 copies)
CGEHFNKO_03373 0.0 ywpD - - T - - - Histidine kinase
CGEHFNKO_03374 3.54e-193 M1-574 - - T - - - Transcriptional regulatory protein, C terminal
CGEHFNKO_03375 0.0 - - - M - - - cell wall anchor domain
CGEHFNKO_03376 5.54e-104 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
CGEHFNKO_03377 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
CGEHFNKO_03378 1.38e-154 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
CGEHFNKO_03379 5.62e-226 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
CGEHFNKO_03380 2.01e-287 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
CGEHFNKO_03381 4.01e-191 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
CGEHFNKO_03382 1.49e-279 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
CGEHFNKO_03383 3.36e-60 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
CGEHFNKO_03384 3.57e-158 yflK - - S - - - protein conserved in bacteria
CGEHFNKO_03385 5.84e-21 yflJ - - S - - - Protein of unknown function (DUF2639)
CGEHFNKO_03386 1.98e-26 yflI - - - - - - -
CGEHFNKO_03387 1.96e-65 yflH - - S - - - Protein of unknown function (DUF3243)
CGEHFNKO_03388 6.62e-178 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
CGEHFNKO_03389 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
CGEHFNKO_03390 8.21e-97 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
CGEHFNKO_03391 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
CGEHFNKO_03392 8.46e-84 ydhN1 - - S - - - Domain of unknown function (DUF1992)
CGEHFNKO_03393 2.48e-105 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
CGEHFNKO_03394 8.17e-52 ydgA - - S - - - Spore germination protein gerPA/gerPF
CGEHFNKO_03395 7.28e-51 ydgB - - S - - - Spore germination protein gerPA/gerPF
CGEHFNKO_03396 1.34e-314 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
CGEHFNKO_03397 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
CGEHFNKO_03398 2.89e-166 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
CGEHFNKO_03399 5.91e-158 frp - - C - - - nitroreductase
CGEHFNKO_03400 6e-167 yibF - - S - - - YibE/F-like protein
CGEHFNKO_03401 2.69e-256 yibE - - S - - - YibE/F-like protein
CGEHFNKO_03403 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
CGEHFNKO_03404 7.82e-118 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
CGEHFNKO_03405 9.13e-239 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
CGEHFNKO_03406 6.12e-210 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CGEHFNKO_03407 2.77e-172 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
CGEHFNKO_03408 1.84e-83 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
CGEHFNKO_03409 2.11e-142 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
CGEHFNKO_03410 1.47e-41 yfkK - - S - - - Belongs to the UPF0435 family
CGEHFNKO_03411 1.69e-112 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CGEHFNKO_03412 5.26e-70 yfkI - - S - - - gas vesicle protein
CGEHFNKO_03413 1.37e-185 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
CGEHFNKO_03414 6.71e-12 - - - - - - - -
CGEHFNKO_03415 3.56e-279 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
CGEHFNKO_03416 8.42e-239 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
CGEHFNKO_03417 8.04e-186 yfkD - - S - - - YfkD-like protein
CGEHFNKO_03418 4.27e-188 yfkC - - M - - - Mechanosensitive ion channel
CGEHFNKO_03419 1.97e-280 yfkA - - S - - - YfkB-like domain
CGEHFNKO_03420 7.99e-37 yfjT - - - - - - -
CGEHFNKO_03421 4.36e-199 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
CGEHFNKO_03422 2.26e-178 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
CGEHFNKO_03424 2.24e-236 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
CGEHFNKO_03425 4.92e-208 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CGEHFNKO_03426 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CGEHFNKO_03427 2.15e-67 - - - S - - - YfzA-like protein
CGEHFNKO_03428 1.41e-243 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CGEHFNKO_03429 1.91e-116 yfjM - - S - - - Psort location Cytoplasmic, score
CGEHFNKO_03430 5.55e-244 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
CGEHFNKO_03431 7.55e-242 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
CGEHFNKO_03432 2.67e-272 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
CGEHFNKO_03433 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
CGEHFNKO_03434 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
CGEHFNKO_03435 6.64e-22 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
CGEHFNKO_03436 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
CGEHFNKO_03437 7.72e-179 glvR - - F ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
CGEHFNKO_03438 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
CGEHFNKO_03439 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
CGEHFNKO_03440 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
CGEHFNKO_03441 5.54e-82 yfiD3 - - S - - - DoxX
CGEHFNKO_03442 1.35e-204 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
CGEHFNKO_03443 1.6e-218 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
CGEHFNKO_03444 5.62e-126 padR - - K - - - transcriptional
CGEHFNKO_03445 1.03e-143 - 1.6.5.2 - S ko:K00355 ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
CGEHFNKO_03446 1.14e-237 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
CGEHFNKO_03447 0.0 - 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
CGEHFNKO_03448 2.87e-61 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
CGEHFNKO_03449 4.66e-128 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
CGEHFNKO_03450 0.0 yfiU - - EGP - - - the major facilitator superfamily
CGEHFNKO_03451 7.97e-108 yfiV - - K - - - transcriptional
CGEHFNKO_03452 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CGEHFNKO_03453 1.86e-211 yfhB - - S - - - PhzF family
CGEHFNKO_03454 8.22e-138 yfhC - - C - - - nitroreductase
CGEHFNKO_03455 3.61e-34 yfhD - - S - - - YfhD-like protein
CGEHFNKO_03457 2.1e-215 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
CGEHFNKO_03458 2.47e-180 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
CGEHFNKO_03459 1.08e-67 yfhH - - S - - - Protein of unknown function (DUF1811)
CGEHFNKO_03460 2.86e-268 yfhI - - EGP - - - -transporter
CGEHFNKO_03462 1.73e-216 mpr - - M - - - Belongs to the peptidase S1B family
CGEHFNKO_03463 2.57e-59 yfhJ - - S - - - WVELL protein
CGEHFNKO_03464 9.84e-123 yfhK - - T - - - Bacterial SH3 domain homologues
CGEHFNKO_03465 1.22e-56 yfhL - - S - - - SdpI/YhfL protein family
CGEHFNKO_03466 1.95e-218 - - - S - - - Alpha/beta hydrolase family
CGEHFNKO_03467 7.79e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
CGEHFNKO_03468 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
CGEHFNKO_03469 4.17e-236 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
CGEHFNKO_03470 3.2e-266 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
CGEHFNKO_03471 2.54e-50 yfhS - - - - - - -
CGEHFNKO_03472 3.81e-173 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CGEHFNKO_03473 3.65e-07 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
CGEHFNKO_03474 1.4e-49 ygaB - - S - - - YgaB-like protein
CGEHFNKO_03475 2.32e-135 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
CGEHFNKO_03476 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
CGEHFNKO_03477 9.11e-240 ygaE - - S - - - Membrane
CGEHFNKO_03478 6.86e-314 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
CGEHFNKO_03479 1.39e-111 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
CGEHFNKO_03480 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
CGEHFNKO_03481 4.67e-75 ygzB - - S - - - UPF0295 protein
CGEHFNKO_03482 2.75e-213 ygxA - - S - - - Nucleotidyltransferase-like
CGEHFNKO_03483 7.1e-226 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CGEHFNKO_03484 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
CGEHFNKO_03485 1.69e-259 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
CGEHFNKO_03486 3.41e-278 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
CGEHFNKO_03487 2.2e-176 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
CGEHFNKO_03488 5.39e-292 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CGEHFNKO_03489 3.38e-251 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CGEHFNKO_03490 1.18e-121 yitZ - - G - - - Major Facilitator Superfamily
CGEHFNKO_03491 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
CGEHFNKO_03492 3.35e-105 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
CGEHFNKO_03493 3.26e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
CGEHFNKO_03494 4.33e-186 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
CGEHFNKO_03495 1.52e-198 - 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
CGEHFNKO_03496 1.49e-11 - - - - - - - -
CGEHFNKO_03497 1.5e-36 - - - S - - - Protein of unknown function (DUF3813)
CGEHFNKO_03498 1.51e-104 ipi - - S - - - Intracellular proteinase inhibitor
CGEHFNKO_03499 1.61e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
CGEHFNKO_03500 7.82e-203 yitS - - S - - - protein conserved in bacteria
CGEHFNKO_03502 1.79e-307 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
CGEHFNKO_03503 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
CGEHFNKO_03504 3.61e-220 - - - S ko:K07335 - ko00000 ABC transporter substrate-binding protein PnrA-like
CGEHFNKO_03505 1.85e-205 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
CGEHFNKO_03506 6.39e-79 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
CGEHFNKO_03507 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
CGEHFNKO_03508 3.78e-106 - - - S - - - Acetyltransferase (GNAT) domain
CGEHFNKO_03509 1.42e-113 yisX - - S - - - Pentapeptide repeats (9 copies)
CGEHFNKO_03510 2.92e-240 yisV - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CGEHFNKO_03511 2.09e-96 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
CGEHFNKO_03512 3.11e-116 yisT - - S - - - DinB family
CGEHFNKO_03513 7.85e-32 - 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
CGEHFNKO_03514 6.71e-206 yisR - - K - - - Transcriptional regulator
CGEHFNKO_03515 3.19e-312 yisQ - - V - - - Mate efflux family protein
CGEHFNKO_03516 3.97e-173 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
CGEHFNKO_03517 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
CGEHFNKO_03518 5.54e-126 yisN - - S - - - Protein of unknown function (DUF2777)
CGEHFNKO_03519 2.22e-78 yisL - - S - - - UPF0344 protein
CGEHFNKO_03520 1.54e-218 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
CGEHFNKO_03521 2.25e-11 yisI - - S - - - Spo0E like sporulation regulatory protein
CGEHFNKO_03522 1.28e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
CGEHFNKO_03523 6.59e-48 gerPB - - S ko:K06300 - ko00000 cell differentiation
CGEHFNKO_03524 1.41e-107 gerPC - - S ko:K06301 - ko00000 Spore germination protein
CGEHFNKO_03525 3e-33 gerPD - - S ko:K06302 - ko00000 Spore germination protein
CGEHFNKO_03526 1.09e-82 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
CGEHFNKO_03527 6.66e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
CGEHFNKO_03528 2.64e-67 yisB - - V - - - COG1403 Restriction endonuclease
CGEHFNKO_03529 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
CGEHFNKO_03530 4.7e-283 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
CGEHFNKO_03531 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
CGEHFNKO_03532 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
CGEHFNKO_03533 5.83e-10 ydfS - - S - - - Protein of unknown function (DUF421)
CGEHFNKO_03534 4.44e-84 ydfS - - S - - - Protein of unknown function (DUF421)
CGEHFNKO_03535 1.79e-122 yhjR - - S - - - Rubrerythrin
CGEHFNKO_03536 2.72e-142 - - - K - - - QacR-like protein, C-terminal region
CGEHFNKO_03537 2.17e-267 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
CGEHFNKO_03538 4.47e-258 yhjN - - S ko:K07120 - ko00000 membrane
CGEHFNKO_03539 1.99e-121 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
CGEHFNKO_03540 0.0 yhjG - - CH - - - FAD binding domain
CGEHFNKO_03541 9.51e-119 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
CGEHFNKO_03542 8.11e-145 yhjE - - S - - - SNARE associated Golgi protein
CGEHFNKO_03543 3.97e-77 yhjD - - - - - - -
CGEHFNKO_03544 1.37e-37 yhjC - - S - - - Protein of unknown function (DUF3311)
CGEHFNKO_03545 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CGEHFNKO_03546 2.64e-63 - - - S - - - Belongs to the UPF0145 family
CGEHFNKO_03547 1.23e-57 yhjA - - S - - - Excalibur calcium-binding domain
CGEHFNKO_03548 6.58e-165 yrpD - - S - - - Domain of unknown function, YrpD
CGEHFNKO_03549 3.6e-122 - - - S - - - MepB protein
CGEHFNKO_03550 1.12e-87 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
CGEHFNKO_03551 1.79e-88 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
CGEHFNKO_03552 1.09e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
CGEHFNKO_03553 1.15e-43 yhzC - - S - - - IDEAL
CGEHFNKO_03554 1.92e-204 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CGEHFNKO_03555 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
CGEHFNKO_03556 6.54e-276 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
CGEHFNKO_03557 7.56e-116 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
CGEHFNKO_03558 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
CGEHFNKO_03559 7.42e-255 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
CGEHFNKO_03560 1.36e-130 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
CGEHFNKO_03561 5.63e-196 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
CGEHFNKO_03562 3.46e-265 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
CGEHFNKO_03563 6.42e-301 yhfN - - O - - - Peptidase M48
CGEHFNKO_03564 6.81e-86 yhfM - - - - - - -
CGEHFNKO_03565 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
CGEHFNKO_03566 2.21e-143 yhfK - - GM - - - NmrA-like family
CGEHFNKO_03567 1.85e-241 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
CGEHFNKO_03568 1.7e-182 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
CGEHFNKO_03570 3.43e-282 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
CGEHFNKO_03571 5.41e-253 yhfE - - G - - - peptidase M42
CGEHFNKO_03573 5.92e-235 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CGEHFNKO_03574 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
CGEHFNKO_03575 3.63e-130 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
CGEHFNKO_03576 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CGEHFNKO_03577 4.49e-232 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
CGEHFNKO_03578 7.35e-259 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CGEHFNKO_03579 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
CGEHFNKO_03580 1.08e-117 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
CGEHFNKO_03581 1.39e-311 yhfA - - C - - - membrane
CGEHFNKO_03582 1.78e-285 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
CGEHFNKO_03583 3.02e-162 ecsC - - S - - - EcsC protein family
CGEHFNKO_03584 2.24e-281 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
CGEHFNKO_03585 1.82e-174 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
CGEHFNKO_03586 5.82e-105 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
CGEHFNKO_03587 2.06e-259 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CGEHFNKO_03588 1.43e-100 trpP - - S - - - Tryptophan transporter TrpP
CGEHFNKO_03589 2.55e-24 - - - - - - - -
CGEHFNKO_03590 4.74e-55 yhaH - - S - - - YtxH-like protein
CGEHFNKO_03591 8.17e-147 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
CGEHFNKO_03592 1.2e-72 yhaI - - S - - - Protein of unknown function (DUF1878)
CGEHFNKO_03593 1.29e-123 yhaK - - S - - - Putative zincin peptidase
CGEHFNKO_03594 7.58e-185 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
CGEHFNKO_03595 1.44e-68 - - - L - - - COG2963 Transposase and inactivated derivatives
CGEHFNKO_03596 2.9e-166 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
CGEHFNKO_03597 5.79e-43 yhaL - - S - - - Sporulation protein YhaL
CGEHFNKO_03598 2.48e-226 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
CGEHFNKO_03599 0.0 yhaN - - L - - - AAA domain
CGEHFNKO_03600 4.14e-297 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
CGEHFNKO_03601 4.14e-278 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
CGEHFNKO_03602 3.92e-215 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
CGEHFNKO_03603 5.99e-21 - - - S - - - YhzD-like protein
CGEHFNKO_03604 4.11e-175 yhaR - - I - - - enoyl-CoA hydratase
CGEHFNKO_03606 7.6e-113 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
CGEHFNKO_03607 1.41e-266 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
CGEHFNKO_03608 0.0 - 1.14.13.59 - Q ko:K03897 ko00310,ko01120,map00310,map01120 ko00000,ko00001,ko01000 L-lysine 6-monooxygenase (NADPH-requiring)
CGEHFNKO_03609 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
CGEHFNKO_03610 1.03e-205 yhaX - - S - - - haloacid dehalogenase-like hydrolase
CGEHFNKO_03611 2.12e-259 yhaZ - - L - - - DNA alkylation repair enzyme
CGEHFNKO_03612 8.1e-71 yheA - - S - - - Belongs to the UPF0342 family
CGEHFNKO_03613 1.36e-264 yheB - - S - - - Belongs to the UPF0754 family
CGEHFNKO_03614 1.32e-273 yheC - - HJ - - - YheC/D like ATP-grasp
CGEHFNKO_03615 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
CGEHFNKO_03616 2.12e-49 yheE - - S - - - Family of unknown function (DUF5342)
CGEHFNKO_03617 1.15e-39 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
CGEHFNKO_03619 2.33e-143 yheG - - GM - - - NAD(P)H-binding
CGEHFNKO_03620 0.0 yheH - - V ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
CGEHFNKO_03621 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
CGEHFNKO_03623 2.49e-110 - - - T - - - universal stress protein
CGEHFNKO_03624 2.29e-125 ymcC - - S - - - Membrane
CGEHFNKO_03625 1.22e-114 pksA - - K - - - Transcriptional regulator
CGEHFNKO_03626 8.4e-198 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
CGEHFNKO_03627 2.83e-200 nodB1 - - G - - - deacetylase
CGEHFNKO_03628 4.16e-180 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
CGEHFNKO_03629 6.68e-262 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
CGEHFNKO_03630 1.45e-08 yhdX - - S - - - Uncharacterized protein YhdX
CGEHFNKO_03631 3.27e-168 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
CGEHFNKO_03632 5.18e-81 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CGEHFNKO_03633 1.01e-70 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CGEHFNKO_03634 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
CGEHFNKO_03635 1.84e-299 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
CGEHFNKO_03636 1.72e-287 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
CGEHFNKO_03637 1.19e-93 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
CGEHFNKO_03638 3.94e-307 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
CGEHFNKO_03639 1.59e-142 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
CGEHFNKO_03640 4.6e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
CGEHFNKO_03641 1.97e-256 yhdL - - S - - - Sigma factor regulator N-terminal
CGEHFNKO_03642 8.62e-59 yhdK - - S - - - Sigma-M inhibitor protein
CGEHFNKO_03643 1.78e-268 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
CGEHFNKO_03644 8.9e-317 yhdG - - E ko:K03294 - ko00000 amino acid
CGEHFNKO_03645 2.25e-205 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CGEHFNKO_03646 5.96e-264 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
CGEHFNKO_03647 7e-210 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
CGEHFNKO_03648 6.44e-177 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
CGEHFNKO_03649 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
CGEHFNKO_03650 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
CGEHFNKO_03651 0.0 ygxB - - M - - - Conserved TM helix
CGEHFNKO_03652 3.25e-97 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
CGEHFNKO_03653 1.27e-298 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
CGEHFNKO_03654 2.42e-70 yhdC - - S - - - Protein of unknown function (DUF3889)
CGEHFNKO_03655 6.98e-53 yhdB - - S - - - YhdB-like protein
CGEHFNKO_03656 5.04e-118 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
CGEHFNKO_03657 1.05e-143 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CGEHFNKO_03658 6.87e-138 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
CGEHFNKO_03659 1.28e-109 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
CGEHFNKO_03660 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
CGEHFNKO_03661 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CGEHFNKO_03662 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CGEHFNKO_03663 8.1e-199 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
CGEHFNKO_03664 5.16e-135 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CGEHFNKO_03665 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CGEHFNKO_03666 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
CGEHFNKO_03667 3.41e-161 yhcW - - S ko:K07025 - ko00000 hydrolase
CGEHFNKO_03668 6.12e-91 yhcV - - S - - - COG0517 FOG CBS domain
CGEHFNKO_03669 2.2e-91 yhcU - - S - - - Family of unknown function (DUF5365)
CGEHFNKO_03670 5.57e-217 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
CGEHFNKO_03671 1.36e-138 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
CGEHFNKO_03672 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
CGEHFNKO_03673 8.63e-151 yhcQ - - M - - - Spore coat protein
CGEHFNKO_03674 3.33e-207 yhcP - - - - - - -
CGEHFNKO_03675 2.69e-122 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
CGEHFNKO_03676 4.09e-82 yhcM - - - - - - -
CGEHFNKO_03677 1.11e-294 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
CGEHFNKO_03678 4.78e-249 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
CGEHFNKO_03679 2.13e-192 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
CGEHFNKO_03680 7.28e-42 cspB - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
CGEHFNKO_03681 3.85e-210 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
CGEHFNKO_03682 2.35e-215 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
CGEHFNKO_03683 8.46e-161 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
CGEHFNKO_03684 1.64e-81 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
CGEHFNKO_03685 2.33e-66 - - - - - - - -
CGEHFNKO_03686 1.41e-72 yhcC - - - - - - -
CGEHFNKO_03687 9.09e-129 wrbA 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
CGEHFNKO_03688 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
CGEHFNKO_03689 1.54e-132 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
CGEHFNKO_03690 1.19e-97 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
CGEHFNKO_03691 1.77e-280 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
CGEHFNKO_03692 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
CGEHFNKO_03693 1.23e-07 - - - - - - - -
CGEHFNKO_03694 1.16e-93 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
CGEHFNKO_03695 1.49e-87 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
CGEHFNKO_03696 1.39e-140 yhbD - - K - - - Protein of unknown function (DUF4004)
CGEHFNKO_03697 8.36e-113 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
CGEHFNKO_03698 6.09e-226 yhbB - - S - - - Putative amidase domain
CGEHFNKO_03699 2.08e-287 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CGEHFNKO_03700 1.11e-146 yhzB - - S - - - B3/4 domain
CGEHFNKO_03702 9.41e-32 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
CGEHFNKO_03703 1.29e-106 ygaO - - - - - - -
CGEHFNKO_03704 2.39e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CGEHFNKO_03705 1.43e-271 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
CGEHFNKO_03706 4.1e-186 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
CGEHFNKO_03707 3.53e-229 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
CGEHFNKO_03708 4.5e-180 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
CGEHFNKO_03709 1.99e-235 - - - S ko:K07045 - ko00000 Amidohydrolase
CGEHFNKO_03710 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
CGEHFNKO_03711 6.64e-168 oppF9 - - E ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
CGEHFNKO_03712 3.65e-168 oppD3 - - P ko:K02031 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
CGEHFNKO_03713 3.58e-161 - - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CGEHFNKO_03714 5.79e-179 - - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
CGEHFNKO_03715 6.34e-291 oppA5 - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 PFAM extracellular solute-binding protein family 5
CGEHFNKO_03717 0.0 ygaK - - C - - - Berberine and berberine like
CGEHFNKO_03718 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CGEHFNKO_03719 3.44e-172 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
CGEHFNKO_03720 0.0 - - - C - - - Na+/H+ antiporter family
CGEHFNKO_03721 3.29e-248 - - - S - - - AIPR protein
CGEHFNKO_03734 1.11e-118 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
CGEHFNKO_03735 5.38e-61 ylaB - - - - - - -
CGEHFNKO_03736 2.84e-241 ylaA - - - - - - -
CGEHFNKO_03737 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
CGEHFNKO_03738 1.3e-108 ykzC - - S - - - Acetyltransferase (GNAT) family
CGEHFNKO_03739 2.33e-195 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
CGEHFNKO_03740 7.89e-32 ykzI - - - - - - -
CGEHFNKO_03741 8.15e-155 yktB - - S - - - Belongs to the UPF0637 family
CGEHFNKO_03742 9.4e-57 yktA - - S - - - Belongs to the UPF0223 family
CGEHFNKO_03743 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
CGEHFNKO_03744 5.69e-192 pdaA_2 3.5.1.104 - G ko:K01567,ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
CGEHFNKO_03745 7.97e-59 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
CGEHFNKO_03746 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
CGEHFNKO_03747 7.27e-302 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
CGEHFNKO_03748 1.01e-226 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
CGEHFNKO_03749 7.79e-261 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
CGEHFNKO_03750 1.36e-266 - - - V - - - Beta-lactamase
CGEHFNKO_03751 0.0 - - - IQ - - - Phosphopantetheine attachment site
CGEHFNKO_03752 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
CGEHFNKO_03753 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
CGEHFNKO_03754 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
CGEHFNKO_03755 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
CGEHFNKO_03756 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 polyketide synthase
CGEHFNKO_03757 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
CGEHFNKO_03758 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
CGEHFNKO_03759 5.6e-134 ykyA - - L - - - Putative cell-wall binding lipoprotein
CGEHFNKO_03760 7.91e-06 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
CGEHFNKO_03761 1.14e-130 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
CGEHFNKO_03762 5.26e-188 ykrA - - S - - - hydrolases of the HAD superfamily
CGEHFNKO_03763 4.45e-42 ykzG - - S - - - Belongs to the UPF0356 family
CGEHFNKO_03764 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CGEHFNKO_03765 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CGEHFNKO_03766 9.71e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
CGEHFNKO_03767 4.33e-196 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
CGEHFNKO_03768 5.87e-313 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
CGEHFNKO_03769 6.37e-60 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
CGEHFNKO_03770 1.07e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
CGEHFNKO_03771 6.35e-18 - - - S - - - Uncharacterized protein YkpC
CGEHFNKO_03772 4.88e-302 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
CGEHFNKO_03773 2.96e-212 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CGEHFNKO_03774 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
CGEHFNKO_03775 1.5e-49 ykoA - - - - - - -
CGEHFNKO_03776 3.77e-138 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
CGEHFNKO_03777 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
CGEHFNKO_03778 4.75e-214 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
CGEHFNKO_03779 1.54e-168 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
CGEHFNKO_03780 4.23e-269 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
CGEHFNKO_03781 2.9e-158 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
CGEHFNKO_03782 6.38e-243 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CGEHFNKO_03783 3.81e-139 yknW - - S - - - Yip1 domain
CGEHFNKO_03784 2.06e-46 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CGEHFNKO_03785 8.37e-108 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
CGEHFNKO_03786 3.21e-122 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
CGEHFNKO_03787 9.69e-310 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
CGEHFNKO_03788 1.71e-241 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
CGEHFNKO_03789 5.52e-139 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
CGEHFNKO_03790 2.53e-218 yknT - - - ko:K06437 - ko00000 -
CGEHFNKO_03791 7.46e-127 rok - - K - - - Repressor of ComK
CGEHFNKO_03792 3.42e-69 ykuV - - CO - - - thiol-disulfide
CGEHFNKO_03793 5.3e-19 ykuV - - CO - - - thiol-disulfide
CGEHFNKO_03794 1.22e-178 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
CGEHFNKO_03795 2.15e-52 ykuS - - S - - - Belongs to the UPF0180 family
CGEHFNKO_03796 2.39e-277 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
CGEHFNKO_03797 2.89e-129 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
CGEHFNKO_03798 1.27e-76 fld - - C ko:K03839 - ko00000 Flavodoxin
CGEHFNKO_03799 1.83e-10 fld - - C ko:K03839 - ko00000 Flavodoxin
CGEHFNKO_03800 1.6e-218 ykuO - - - - - - -
CGEHFNKO_03801 1.28e-116 ykuN - - C ko:K03839 - ko00000 Flavodoxin
CGEHFNKO_03802 1.32e-215 ccpC - - K - - - Transcriptional regulator
CGEHFNKO_03803 8.55e-99 ykuL - - S - - - CBS domain
CGEHFNKO_03804 4.54e-37 ykzF - - S - - - Antirepressor AbbA
CGEHFNKO_03805 1.52e-120 ykuK - - S ko:K09776 - ko00000 Ribonuclease H-like
CGEHFNKO_03806 3.63e-50 ykuJ - - S - - - protein conserved in bacteria
CGEHFNKO_03807 7.72e-297 ykuI - - T - - - Diguanylate phosphodiesterase
CGEHFNKO_03809 4.31e-181 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CGEHFNKO_03810 3.14e-198 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
CGEHFNKO_03811 3.62e-116 ykuD - - S - - - protein conserved in bacteria
CGEHFNKO_03812 7.96e-309 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
CGEHFNKO_03813 1.02e-107 ykyB - - S - - - YkyB-like protein
CGEHFNKO_03814 4.75e-214 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
CGEHFNKO_03815 6.38e-15 - - - - - - - -
CGEHFNKO_03816 6.61e-275 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
CGEHFNKO_03817 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
CGEHFNKO_03818 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
CGEHFNKO_03819 1.87e-158 ykwD - - J - - - protein with SCP PR1 domains
CGEHFNKO_03820 5.02e-18 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
CGEHFNKO_03821 1.27e-69 - - - - - - - -
CGEHFNKO_03822 1.15e-202 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
CGEHFNKO_03823 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
CGEHFNKO_03824 1.68e-254 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
CGEHFNKO_03825 3.63e-50 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
CGEHFNKO_03826 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CGEHFNKO_03827 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
CGEHFNKO_03828 0.0 ptsG 2.7.1.199 - G ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
CGEHFNKO_03829 2.78e-199 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
CGEHFNKO_03830 8.27e-224 ykvZ - - K - - - Transcriptional regulator
CGEHFNKO_03832 1.92e-262 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
CGEHFNKO_03833 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
CGEHFNKO_03834 3.49e-113 stoA - - CO - - - thiol-disulfide
CGEHFNKO_03835 5.37e-306 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CGEHFNKO_03836 1.45e-142 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
CGEHFNKO_03837 4.16e-38 - - - - - - - -
CGEHFNKO_03838 5.43e-35 ykvS - - S - - - protein conserved in bacteria
CGEHFNKO_03839 1.21e-58 ykvR - - S - - - Protein of unknown function (DUF3219)
CGEHFNKO_03841 7.12e-204 - - - G - - - Glycosyl hydrolases family 18
CGEHFNKO_03842 3.08e-47 - 3.5.1.104 - M ko:K22278 - ko00000,ko01000 LysM domain
CGEHFNKO_03843 2.88e-270 - - - M - - - Glycosyl transferases group 1
CGEHFNKO_03844 2.19e-48 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CGEHFNKO_03845 1.27e-170 ykvO - - IQ - - - Enoyl-(Acyl carrier protein) reductase
CGEHFNKO_03846 1e-79 - - - K - - - HxlR-like helix-turn-helix
CGEHFNKO_03848 2.56e-124 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CGEHFNKO_03849 8.4e-178 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
CGEHFNKO_03850 8.23e-106 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
CGEHFNKO_03851 4.51e-161 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CGEHFNKO_03852 9.75e-256 - - - - - - - -
CGEHFNKO_03853 6.6e-233 ykvI - - S - - - membrane
CGEHFNKO_03854 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
CGEHFNKO_03855 1.17e-176 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
CGEHFNKO_03856 4.04e-169 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
CGEHFNKO_03857 3.34e-101 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
CGEHFNKO_03858 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
CGEHFNKO_03860 2.6e-124 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CGEHFNKO_03861 9.5e-149 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
CGEHFNKO_03862 8.1e-176 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
CGEHFNKO_03863 1.84e-287 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
CGEHFNKO_03864 4.42e-292 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
CGEHFNKO_03865 4.7e-192 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
CGEHFNKO_03866 2.44e-287 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
CGEHFNKO_03867 1.81e-250 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CGEHFNKO_03869 3.62e-111 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CGEHFNKO_03870 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
CGEHFNKO_03871 6.46e-242 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
CGEHFNKO_03872 2.53e-31 ykzE - - - - - - -
CGEHFNKO_03873 6.05e-148 - - - S - - - Protein of unknown function (DUF421)
CGEHFNKO_03874 8.94e-307 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
CGEHFNKO_03875 6.35e-200 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
CGEHFNKO_03876 4.44e-159 ykrK - - S - - - Domain of unknown function (DUF1836)
CGEHFNKO_03877 2.33e-35 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
CGEHFNKO_03878 3.44e-248 ykrI - - S - - - Anti-sigma factor N-terminus
CGEHFNKO_03879 6.02e-163 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CGEHFNKO_03880 3.54e-174 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
CGEHFNKO_03881 1.17e-130 ykoX - - S - - - membrane-associated protein
CGEHFNKO_03882 5.68e-201 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CGEHFNKO_03883 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
CGEHFNKO_03884 5.41e-129 ykoP - - G - - - polysaccharide deacetylase
CGEHFNKO_03885 1.98e-105 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
CGEHFNKO_03886 5.25e-37 ykoL - - - - - - -
CGEHFNKO_03887 1.11e-23 - - - - - - - -
CGEHFNKO_03888 1.23e-69 tnrA - - K - - - transcriptional
CGEHFNKO_03889 8.66e-310 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
CGEHFNKO_03891 5.38e-311 ydhD - - M - - - Glycosyl hydrolase
CGEHFNKO_03892 1.98e-127 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
CGEHFNKO_03893 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
CGEHFNKO_03894 2.66e-170 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
CGEHFNKO_03895 4.65e-192 yojH - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
CGEHFNKO_03896 9e-227 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
CGEHFNKO_03897 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CGEHFNKO_03898 3.7e-154 nsr - - T - - - COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
CGEHFNKO_03899 8.04e-277 - - - EGP ko:K05820 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
CGEHFNKO_03900 1.65e-173 - - - M - - - PFAM Collagen triple helix repeat (20 copies)
CGEHFNKO_03901 8.64e-276 - - - M - - - Glycosyl transferase family 2
CGEHFNKO_03903 1.83e-86 - - - D - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CGEHFNKO_03904 1.92e-92 ohrB - - O - - - Organic hydroperoxide resistance protein
CGEHFNKO_03905 7.54e-115 ohrR - - K - - - COG1846 Transcriptional regulators
CGEHFNKO_03906 1.39e-92 ohrA - - O - - - Organic hydroperoxide resistance protein
CGEHFNKO_03907 5.59e-290 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CGEHFNKO_03908 3.73e-263 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CGEHFNKO_03909 5.81e-218 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
CGEHFNKO_03910 1.04e-65 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
CGEHFNKO_03911 2.02e-69 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
CGEHFNKO_03912 1.34e-132 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
CGEHFNKO_03913 2.16e-120 ykhA - - I - - - Acyl-CoA hydrolase
CGEHFNKO_03914 4.19e-204 ykgA - - E - - - Amidinotransferase
CGEHFNKO_03915 4.17e-263 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
CGEHFNKO_03916 8.06e-232 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
CGEHFNKO_03917 2.66e-218 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
CGEHFNKO_03918 1.83e-256 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
CGEHFNKO_03919 6.58e-225 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
CGEHFNKO_03920 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
CGEHFNKO_03921 2.64e-242 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
CGEHFNKO_03922 2.68e-226 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CGEHFNKO_03923 1.39e-204 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CGEHFNKO_03924 4.36e-200 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
CGEHFNKO_03926 0.0 yubD - - P - - - Major Facilitator Superfamily
CGEHFNKO_03927 3.21e-277 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CGEHFNKO_03929 1.56e-229 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
CGEHFNKO_03930 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CGEHFNKO_03931 3.43e-234 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
CGEHFNKO_03932 1.33e-311 steT - - E ko:K03294 - ko00000 amino acid
CGEHFNKO_03933 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
CGEHFNKO_03934 8.61e-227 pit - - P ko:K03306 - ko00000 phosphate transporter
CGEHFNKO_03935 3.81e-172 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
CGEHFNKO_03936 2.53e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
CGEHFNKO_03937 1.73e-215 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
CGEHFNKO_03938 3.87e-51 xhlB - - S - - - SPP1 phage holin
CGEHFNKO_03939 3.87e-51 xhlA - - S - - - Haemolysin XhlA
CGEHFNKO_03940 1.74e-175 xepA - - - - - - -
CGEHFNKO_03941 4.61e-40 xkdX - - - - - - -
CGEHFNKO_03943 8.92e-84 - - - - - - - -
CGEHFNKO_03944 1.54e-38 - - - - - - - -
CGEHFNKO_03945 2.48e-113 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
CGEHFNKO_03946 5.34e-213 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
CGEHFNKO_03947 1.65e-75 xkdS - - S - - - Protein of unknown function (DUF2634)
CGEHFNKO_03948 2.51e-43 xkdR - - S - - - Protein of unknown function (DUF2577)
CGEHFNKO_03949 1.08e-205 xkdQ - - G - - - NLP P60 protein
CGEHFNKO_03950 1.61e-145 xkdP - - S - - - Lysin motif
CGEHFNKO_03951 7.85e-277 xkdO - - L - - - Transglycosylase SLT domain
CGEHFNKO_03952 4.33e-27 - - - - - - - -
CGEHFNKO_03953 7.28e-96 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
CGEHFNKO_03954 8.21e-97 xkdM - - S - - - Phage tail tube protein
CGEHFNKO_03955 2.31e-287 xkdK - - S - - - Phage tail sheath C-terminal domain
CGEHFNKO_03956 2.72e-21 - - - - - - - -
CGEHFNKO_03957 4.28e-74 xkdJ - - - - - - -
CGEHFNKO_03958 2.41e-77 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
CGEHFNKO_03959 5.78e-56 - - - S - - - Domain of unknown function (DUF3599)
CGEHFNKO_03960 1.78e-60 yqbG - - S - - - Protein of unknown function (DUF3199)
CGEHFNKO_03961 8.3e-203 xkdG - - S - - - Phage capsid family
CGEHFNKO_03962 8.8e-119 xkdF3 - - L - - - Putative phage serine protease XkdF
CGEHFNKO_03963 2.99e-303 xkdE3 - - S - - - portal protein
CGEHFNKO_03964 1.59e-261 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
CGEHFNKO_03965 3.38e-140 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
CGEHFNKO_03966 1.07e-110 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
CGEHFNKO_03970 7.52e-197 xkdC - - L - - - Bacterial dnaA protein
CGEHFNKO_03972 6.52e-75 xre - - K - - - Helix-turn-helix XRE-family like proteins
CGEHFNKO_03973 1.87e-142 xkdA - - E - - - IrrE N-terminal-like domain
CGEHFNKO_03974 1.85e-142 yjqB - - S - - - phage-related replication protein
CGEHFNKO_03975 3.87e-80 yjqA - - S - - - Bacterial PH domain
CGEHFNKO_03976 3.36e-221 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
CGEHFNKO_03978 2.68e-275 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
CGEHFNKO_03979 1.02e-103 yjoA - - S - - - DinB family
CGEHFNKO_03980 1.31e-166 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
CGEHFNKO_03981 0.0 uxaA 4.2.1.7 - G ko:K01685 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
CGEHFNKO_03982 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
CGEHFNKO_03983 1.24e-235 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
CGEHFNKO_03984 0.0 - - - G ko:K03292 - ko00000 symporter YjmB
CGEHFNKO_03985 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
CGEHFNKO_03986 7.49e-281 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
CGEHFNKO_03987 1.7e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
CGEHFNKO_03988 2.02e-117 yjlB - - S - - - Cupin domain
CGEHFNKO_03989 2.48e-228 yjlA - - EG - - - Putative multidrug resistance efflux transporter
CGEHFNKO_03990 9.22e-168 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 Belongs to the ABC transporter superfamily
CGEHFNKO_03991 2.4e-157 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
CGEHFNKO_03992 9.25e-184 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
CGEHFNKO_03993 1.73e-40 - - - - - - - -
CGEHFNKO_03994 6.22e-286 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
CGEHFNKO_03995 7.66e-292 yjiB 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
CGEHFNKO_03996 2.2e-117 yjgD - - S - - - Protein of unknown function (DUF1641)
CGEHFNKO_03997 0.0 - 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
CGEHFNKO_03998 1.43e-131 yjgB - - S - - - Domain of unknown function (DUF4309)
CGEHFNKO_03999 2.1e-90 yjgA - - T - - - Protein of unknown function (DUF2809)
CGEHFNKO_04000 9.12e-30 yjfB - - S - - - Putative motility protein
CGEHFNKO_04002 2.48e-136 - - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
CGEHFNKO_04004 2.92e-171 - - - N - - - Kelch motif
CGEHFNKO_04005 3.41e-160 - - - S - - - Haloacid dehalogenase-like hydrolase
CGEHFNKO_04006 1.19e-178 yulB - - K ko:K02530 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
CGEHFNKO_04007 0.0 lacG 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
CGEHFNKO_04008 3.63e-66 celC 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
CGEHFNKO_04009 0.0 lacE 2.7.1.207 - G ko:K02761,ko:K02787,ko:K02788 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CGEHFNKO_04010 1.05e-274 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CGEHFNKO_04011 3.61e-243 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
CGEHFNKO_04012 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
CGEHFNKO_04013 9.4e-282 yvfO 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
CGEHFNKO_04014 6.11e-106 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
CGEHFNKO_04015 0.0 yfjF - - EGP - - - Belongs to the major facilitator superfamily
CGEHFNKO_04016 6.3e-61 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
CGEHFNKO_04017 1.64e-210 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
CGEHFNKO_04022 1.09e-94 - - - E - - - phosphoribosylanthranilate isomerase activity
CGEHFNKO_04023 7.16e-64 - - - FG ko:K02503 - ko00000,ko04147 HIT domain
CGEHFNKO_04025 5.64e-14 ywlA - - S - - - Uncharacterised protein family (UPF0715)
CGEHFNKO_04026 1.64e-170 - - - - - - - -
CGEHFNKO_04029 7.65e-119 - - - - - - - -
CGEHFNKO_04030 5.79e-10 - - - L ko:K21487 - ko00000,ko01000,ko02048 Belongs to the WXG100 family
CGEHFNKO_04031 5.51e-42 - - - S - - - Bacterial EndoU nuclease
CGEHFNKO_04032 1.05e-75 - - - - - - - -
CGEHFNKO_04033 0.0 - - - Q - - - TIGRFAM amino acid adenylation domain
CGEHFNKO_04034 1.81e-59 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
CGEHFNKO_04036 8.77e-282 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CGEHFNKO_04037 2.47e-73 swrA - - S - - - Swarming motility protein
CGEHFNKO_04038 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
CGEHFNKO_04039 9.93e-304 ywoF - - P - - - Right handed beta helix region
CGEHFNKO_04040 2.48e-198 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
CGEHFNKO_04041 8.68e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
CGEHFNKO_04042 3.08e-60 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
CGEHFNKO_04043 6.85e-192 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
CGEHFNKO_04044 6.64e-233 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CGEHFNKO_04045 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
CGEHFNKO_04046 3.94e-133 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CGEHFNKO_04047 1.84e-87 - - - - - - - -
CGEHFNKO_04048 4.35e-10 fliT - - N ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
CGEHFNKO_04049 5.79e-88 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
CGEHFNKO_04050 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CGEHFNKO_04051 1.3e-152 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CGEHFNKO_04052 2.67e-43 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CGEHFNKO_04053 5.2e-98 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
CGEHFNKO_04054 1.62e-107 yviE - - - - - - -
CGEHFNKO_04055 1.2e-208 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
CGEHFNKO_04056 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
CGEHFNKO_04057 2.2e-105 yvyG - - NOU - - - FlgN protein
CGEHFNKO_04058 6.14e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
CGEHFNKO_04059 1.1e-97 yvyF - - S - - - flagellar protein
CGEHFNKO_04060 2.84e-85 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
CGEHFNKO_04061 3.56e-57 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
CGEHFNKO_04062 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CGEHFNKO_04063 3.59e-203 degV - - S - - - protein conserved in bacteria
CGEHFNKO_04064 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CGEHFNKO_04065 3.44e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
CGEHFNKO_04066 3.43e-154 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
CGEHFNKO_04067 8.97e-229 yvhJ - - K - - - Transcriptional regulator
CGEHFNKO_04068 3.12e-233 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
CGEHFNKO_04069 1.98e-304 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
CGEHFNKO_04070 6.92e-186 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
CGEHFNKO_04071 6.04e-149 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
CGEHFNKO_04072 0.0 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
CGEHFNKO_04073 0.0 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CGEHFNKO_04074 1.46e-281 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
CGEHFNKO_04075 0.0 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CGEHFNKO_04076 4.22e-151 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
CGEHFNKO_04077 0.0 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
CGEHFNKO_04078 0.0 lytB - - D - - - Stage II sporulation protein
CGEHFNKO_04079 3.22e-65 - - - - - - - -
CGEHFNKO_04080 4.48e-204 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)