ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
GFGFMMDL_00001 5.47e-42 - - - K - - - Peptidase S24-like
GFGFMMDL_00003 0.0 - - - - - - - -
GFGFMMDL_00004 0.0 mycA 4.2.1.53 - S ko:K10254 - ko00000,ko01000 MCRA family
GFGFMMDL_00005 1.46e-68 - - - - - - - -
GFGFMMDL_00006 3.03e-64 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
GFGFMMDL_00007 2.51e-56 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
GFGFMMDL_00008 2.72e-30 - - - L - - - Integrase core domain protein
GFGFMMDL_00009 2.34e-128 - - - L ko:K07485 - ko00000 Transposase
GFGFMMDL_00010 6.44e-65 - - - L - - - Transposase
GFGFMMDL_00027 6.73e-180 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
GFGFMMDL_00028 7.75e-115 mreD - - M ko:K03571 - ko00000,ko03036 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GFGFMMDL_00029 2.51e-180 pcsB - - S ko:K21471 - ko00000,ko01000,ko01002,ko01011 CHAP domain
GFGFMMDL_00030 4.76e-224 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GFGFMMDL_00031 2.59e-279 araT - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
GFGFMMDL_00032 1.45e-185 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
GFGFMMDL_00033 7.72e-231 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
GFGFMMDL_00034 1.93e-46 acpP_1 - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
GFGFMMDL_00035 1.5e-167 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
GFGFMMDL_00036 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GFGFMMDL_00037 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GFGFMMDL_00038 2.43e-239 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
GFGFMMDL_00039 4.63e-130 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GFGFMMDL_00040 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
GFGFMMDL_00041 5.2e-100 - - - L ko:K07483 - ko00000 transposase activity
GFGFMMDL_00042 2.08e-66 - - - L ko:K07497 - ko00000 transposition
GFGFMMDL_00043 2.32e-43 - - - L ko:K07497 - ko00000 Integrase core domain protein
GFGFMMDL_00044 4.38e-207 - - - S - - - CHAP domain
GFGFMMDL_00045 1.65e-305 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
GFGFMMDL_00046 2.66e-99 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GFGFMMDL_00047 1.4e-259 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GFGFMMDL_00048 3.19e-111 - 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Ketopantoate reductase
GFGFMMDL_00049 1.21e-44 - - - - - - - -
GFGFMMDL_00050 3.66e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GFGFMMDL_00051 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
GFGFMMDL_00052 1.36e-90 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
GFGFMMDL_00053 5.42e-75 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
GFGFMMDL_00054 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GFGFMMDL_00055 5.95e-101 - - - S - - - Protein of unknown function (DUF3021)
GFGFMMDL_00057 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GFGFMMDL_00059 4.38e-134 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
GFGFMMDL_00060 3.64e-90 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 3-methyladenine DNA glycosylase
GFGFMMDL_00061 2.8e-294 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
GFGFMMDL_00062 5.07e-261 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GFGFMMDL_00063 1.27e-86 spxA_2 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
GFGFMMDL_00071 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GFGFMMDL_00072 2.31e-297 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
GFGFMMDL_00073 4.88e-49 XK27_02060 - - S - - - Transglycosylase associated protein
GFGFMMDL_00074 2.92e-69 badR - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
GFGFMMDL_00075 9.33e-125 XK27_03570 - - S ko:K19784 - ko00000 reductase
GFGFMMDL_00076 7.42e-44 - - - L ko:K07497 - ko00000 Integrase core domain protein
GFGFMMDL_00077 2.27e-219 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
GFGFMMDL_00079 2.48e-176 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
GFGFMMDL_00080 2.46e-232 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GFGFMMDL_00081 1.69e-107 - - - S - - - Putative small multi-drug export protein
GFGFMMDL_00082 6.68e-98 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
GFGFMMDL_00083 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
GFGFMMDL_00084 2.46e-89 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
GFGFMMDL_00085 2.11e-71 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
GFGFMMDL_00086 1.38e-295 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
GFGFMMDL_00087 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
GFGFMMDL_00088 2.22e-184 - - - S - - - SseB protein N-terminal domain
GFGFMMDL_00089 7.75e-145 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 serine acetyltransferase
GFGFMMDL_00090 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
GFGFMMDL_00091 4.95e-89 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GFGFMMDL_00094 4.11e-171 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GFGFMMDL_00095 3.32e-119 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
GFGFMMDL_00096 8.7e-197 yitS - - S - - - DegV family
GFGFMMDL_00098 1.34e-232 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GFGFMMDL_00099 7.02e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GFGFMMDL_00100 6.08e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
GFGFMMDL_00101 2.63e-283 capA - - M ko:K07282 - ko00000 Bacterial capsule synthesis protein
GFGFMMDL_00102 3.56e-52 XK27_08630 - - T ko:K07166 - ko00000 UPF0237 protein
GFGFMMDL_00103 1.95e-308 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
GFGFMMDL_00104 1.76e-170 gpmB - - G ko:K15640 - ko00000 Phosphoglycerate mutase
GFGFMMDL_00105 4.99e-181 yodJ 3.4.16.4, 3.4.17.14 - M ko:K01286,ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
GFGFMMDL_00106 7.28e-132 acmA 3.2.1.17 - NU ko:K01185,ko:K02395 - ko00000,ko01000,ko02035 amidase activity
GFGFMMDL_00107 2.56e-249 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
GFGFMMDL_00108 3.66e-101 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GFGFMMDL_00109 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
GFGFMMDL_00110 4.64e-253 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
GFGFMMDL_00111 7.15e-177 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
GFGFMMDL_00112 1.49e-176 thiD 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 phosphomethylpyrimidine kinase
GFGFMMDL_00113 1.95e-95 hmpT - - S - - - cog cog4720
GFGFMMDL_00114 7.24e-102 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 DNA-templated transcription, initiation
GFGFMMDL_00115 7.65e-188 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
GFGFMMDL_00116 6.19e-284 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
GFGFMMDL_00117 8.37e-116 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
GFGFMMDL_00118 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
GFGFMMDL_00119 1.69e-107 XK27_03960 - - S - - - Protein of unknown function (DUF3013)
GFGFMMDL_00120 4.23e-104 - 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
GFGFMMDL_00121 2.47e-223 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
GFGFMMDL_00122 3.02e-173 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
GFGFMMDL_00123 1.78e-55 - 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 nucleotide catabolic process
GFGFMMDL_00124 1.02e-240 cpdB 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
GFGFMMDL_00125 3.34e-167 cpdB 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
GFGFMMDL_00126 6.8e-108 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
GFGFMMDL_00127 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GFGFMMDL_00128 2.86e-97 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
GFGFMMDL_00129 3.09e-13 dex 3.2.1.11 GH66 G ko:K05988 ko00500,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolase family 66
GFGFMMDL_00130 4.07e-34 dex 3.2.1.11 GH66 G ko:K05988 ko00500,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolase family 66
GFGFMMDL_00131 9.76e-23 dex 3.2.1.11 GH66 G ko:K05988 ko00500,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolase family 66
GFGFMMDL_00132 2.53e-52 dex 3.2.1.11 GH66 G ko:K05988 ko00500,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolase family 66
GFGFMMDL_00133 1.3e-300 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GFGFMMDL_00134 1.71e-144 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
GFGFMMDL_00135 2.7e-145 - - - K - - - Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
GFGFMMDL_00136 1.23e-256 XK27_00055 - - P - - - Major Facilitator
GFGFMMDL_00137 1.74e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GFGFMMDL_00138 3.45e-125 - - - V - - - VanZ like family
GFGFMMDL_00139 7.59e-10 - - - D - - - nuclear chromosome segregation
GFGFMMDL_00141 8.61e-168 glnQ - - E ko:K17076 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
GFGFMMDL_00142 0.0 XK27_05795 - - P ko:K17073,ko:K17074 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GFGFMMDL_00143 1.18e-194 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
GFGFMMDL_00144 7.11e-173 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
GFGFMMDL_00145 5.94e-247 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
GFGFMMDL_00146 3.66e-184 sufC - - O ko:K09013 - ko00000,ko02000 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
GFGFMMDL_00147 8.42e-299 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
GFGFMMDL_00148 2.82e-301 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GFGFMMDL_00149 2.9e-97 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
GFGFMMDL_00150 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
GFGFMMDL_00151 7.94e-23 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
GFGFMMDL_00152 1.34e-178 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
GFGFMMDL_00153 1.6e-36 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GFGFMMDL_00154 1.5e-52 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GFGFMMDL_00155 3.78e-56 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GFGFMMDL_00156 2.01e-34 oppD - - P ko:K02031,ko:K02032,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GFGFMMDL_00157 1.15e-43 oppD - - P ko:K02031,ko:K02032,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GFGFMMDL_00158 1.28e-85 - - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GFGFMMDL_00159 1.94e-56 oppD - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GFGFMMDL_00160 4.34e-55 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GFGFMMDL_00161 5.59e-121 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GFGFMMDL_00162 2.04e-05 - - - - - - - -
GFGFMMDL_00163 1.2e-15 - - - - - - - -
GFGFMMDL_00164 9.47e-202 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GFGFMMDL_00165 2.41e-234 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GFGFMMDL_00166 1.03e-284 - - - EGP - - - Major facilitator Superfamily
GFGFMMDL_00167 1.28e-94 adcR - - K - - - transcriptional
GFGFMMDL_00168 5.07e-175 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GFGFMMDL_00169 2.06e-164 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
GFGFMMDL_00170 1.45e-208 mleP2 - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
GFGFMMDL_00171 3.61e-80 ptsG 2.7.1.208 - G ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
GFGFMMDL_00172 0.0 ptsG 2.7.1.208 - G ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
GFGFMMDL_00173 1.51e-196 rgfB 3.1.3.90 - L ko:K06896 ko00500,map00500 ko00000,ko00001,ko01000 Endonuclease/Exonuclease/phosphatase family
GFGFMMDL_00174 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
GFGFMMDL_00175 5.12e-159 yeeN - - K - - - transcriptional regulatory protein
GFGFMMDL_00176 1.87e-65 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 protein transport
GFGFMMDL_00177 3.17e-179 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GFGFMMDL_00178 1.75e-185 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
GFGFMMDL_00179 2.12e-292 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
GFGFMMDL_00180 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
GFGFMMDL_00181 0.0 XK27_00665 - - S ko:K01989,ko:K05832 - ko00000,ko00002,ko02000 ABC transporter substrate binding protein
GFGFMMDL_00182 8.63e-183 cmpC - - S ko:K05833 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
GFGFMMDL_00183 2.13e-55 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GFGFMMDL_00184 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
GFGFMMDL_00185 1.41e-105 - - - L ko:K07485 - ko00000 Transposase
GFGFMMDL_00186 2.6e-132 - - - L - - - Transposase
GFGFMMDL_00187 3.91e-33 - - - K - - - Transcriptional regulator
GFGFMMDL_00188 2.6e-14 - - - - - - - -
GFGFMMDL_00191 4.56e-76 - - - S - - - very-long-chain-acyl-CoA dehydrogenase activity
GFGFMMDL_00192 5.35e-90 - - - - - - - -
GFGFMMDL_00194 9.99e-89 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
GFGFMMDL_00196 3.11e-171 drrA - - V ko:K01990,ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GFGFMMDL_00197 1.02e-136 - - - CP - - - ABC-2 family transporter protein
GFGFMMDL_00198 3.54e-169 - 1.6.5.5 - C ko:K00344 - ko00000,ko01000 NADPH:quinone reductase activity
GFGFMMDL_00199 4.21e-25 - - - L - - - Transposase
GFGFMMDL_00200 2.74e-34 - - - - - - - -
GFGFMMDL_00203 1.16e-57 - - - - - - - -
GFGFMMDL_00204 5.62e-75 WQ51_06355 - - S - - - TM2 domain
GFGFMMDL_00205 1.17e-212 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
GFGFMMDL_00206 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
GFGFMMDL_00207 2.56e-34 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Belongs to the SecE SEC61-gamma family
GFGFMMDL_00208 2.8e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
GFGFMMDL_00209 4.1e-111 - 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 - I ko:K01096,ko:K19302 ko00550,ko00564,ko01100,map00550,map00564,map01100 ko00000,ko00001,ko01000,ko01011 phosphatidate phosphatase activity
GFGFMMDL_00210 2.87e-61 cof - - Q - - - phosphatase activity
GFGFMMDL_00211 2.69e-47 cof - - Q - - - phosphatase activity
GFGFMMDL_00212 2.5e-47 - - - K ko:K22103 - ko00000,ko03000 transcriptional regulator (DeoR family)
GFGFMMDL_00213 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
GFGFMMDL_00214 2.72e-97 napB - - K - - - transcriptional
GFGFMMDL_00215 8.68e-296 - - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
GFGFMMDL_00216 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GFGFMMDL_00217 6.15e-195 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
GFGFMMDL_00218 1.32e-97 yhaI - - L - - - Membrane
GFGFMMDL_00219 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
GFGFMMDL_00220 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
GFGFMMDL_00221 9.56e-139 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
GFGFMMDL_00222 3.59e-123 ypsA - - S - - - Belongs to the UPF0398 family
GFGFMMDL_00223 1.97e-66 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
GFGFMMDL_00224 3.56e-282 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
GFGFMMDL_00225 0.0 mapZ - - D ko:K20073 - ko00000 Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
GFGFMMDL_00226 0.0 snf - - L - - - Superfamily II DNA RNA helicases, SNF2 family'
GFGFMMDL_00227 1.54e-25 XK27_11680 - - - - - - -
GFGFMMDL_00228 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
GFGFMMDL_00229 4.85e-102 XK27_09675 - - K ko:K07105 - ko00000 -acetyltransferase
GFGFMMDL_00230 0.0 mltG - - ADL ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GFGFMMDL_00231 8.25e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GFGFMMDL_00232 3.2e-59 - - - L ko:K07497 - ko00000 transposition
GFGFMMDL_00233 7.23e-210 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GFGFMMDL_00234 1.64e-61 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
GFGFMMDL_00235 4.81e-169 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GFGFMMDL_00236 1.86e-114 XK27_09705 - - S ko:K06950 - ko00000 HD superfamily hydrolase
GFGFMMDL_00237 2e-144 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
GFGFMMDL_00240 1.42e-310 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
GFGFMMDL_00241 1.01e-117 - - - K - - - transcriptional regulator
GFGFMMDL_00242 5.74e-48 - - - S ko:K09976 - ko00000 UPF0154 protein
GFGFMMDL_00243 5.43e-188 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
GFGFMMDL_00244 1.64e-236 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GFGFMMDL_00245 1.3e-126 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
GFGFMMDL_00246 2.48e-111 ykuL - - S - - - CBS domain
GFGFMMDL_00247 2.39e-174 xerD - - L - - - tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
GFGFMMDL_00248 6.76e-156 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GFGFMMDL_00249 7.56e-129 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GFGFMMDL_00250 3.14e-179 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
GFGFMMDL_00251 1.05e-53 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
GFGFMMDL_00252 0.0 trkH - - P ko:K03498 - ko00000,ko02000 Cation transport protein
GFGFMMDL_00253 4.47e-311 trkA - - P ko:K03499 - ko00000,ko02000 Potassium transporter peripheral membrane component
GFGFMMDL_00254 1.34e-125 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
GFGFMMDL_00255 4.83e-118 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GFGFMMDL_00256 1.28e-145 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Membrane-associated phospholipid phosphatase
GFGFMMDL_00257 3.58e-207 - - - K ko:K20342,ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 sequence-specific DNA binding
GFGFMMDL_00258 3.36e-46 - - - V ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 protein secretion by the type I secretion system
GFGFMMDL_00259 2.45e-141 comA - - V ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
GFGFMMDL_00260 1.3e-91 comA - - V ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
GFGFMMDL_00261 3.84e-105 comA - - V ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
GFGFMMDL_00262 2.68e-64 yhaI - - L - - - Membrane
GFGFMMDL_00263 4.27e-69 - - - S - - - Domain of unknown function (DUF4173)
GFGFMMDL_00264 6.21e-124 ureI - - S ko:K03191 ko05120,map05120 ko00000,ko00001,ko02000 AmiS/UreI family transporter
GFGFMMDL_00265 1.02e-61 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
GFGFMMDL_00266 3.78e-72 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
GFGFMMDL_00267 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
GFGFMMDL_00268 2.74e-101 ureE - - O ko:K03187 - ko00000 enzyme active site formation
GFGFMMDL_00269 3.03e-168 ureF - - O ko:K03188 - ko00000 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
GFGFMMDL_00270 4.71e-142 ureG - - KO ko:K03189 - ko00000 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GFGFMMDL_00271 8.49e-205 ureD - - O ko:K03190 - ko00000 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
GFGFMMDL_00272 4.79e-225 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PDGLE domain
GFGFMMDL_00273 1.18e-176 nikQ - - P ko:K02008 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport protein
GFGFMMDL_00274 5.02e-167 - - - P ko:K02006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GFGFMMDL_00275 1.19e-176 - - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
GFGFMMDL_00276 2.14e-202 metQ - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
GFGFMMDL_00277 0.0 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
GFGFMMDL_00278 1.28e-235 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GFGFMMDL_00279 3.34e-148 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
GFGFMMDL_00280 2.96e-267 sstT - - E ko:K07862 - ko00000,ko02000 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
GFGFMMDL_00281 1.78e-203 ilvH - - S - - - S-adenosyl-l-methionine hydroxide adenosyltransferase
GFGFMMDL_00282 1.33e-123 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
GFGFMMDL_00283 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
GFGFMMDL_00284 2.39e-189 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
GFGFMMDL_00285 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GFGFMMDL_00286 2.41e-15 ulaG - - S ko:K03476 ko00053,ko01100,ko01120,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 L-ascorbate 6-phosphate lactonase
GFGFMMDL_00287 1.98e-157 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
GFGFMMDL_00288 1.05e-307 ktrB - - P ko:K03498 - ko00000,ko02000 COG0168 Trk-type K transport systems, membrane components
GFGFMMDL_00289 2.13e-168 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Ribosomal RNA small subunit methyltransferase G
GFGFMMDL_00290 2.8e-119 ylbN - - K ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
GFGFMMDL_00291 2.69e-158 csrR - - T - - - Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GFGFMMDL_00292 0.0 covS - - T - - - Histidine kinase
GFGFMMDL_00293 1.46e-106 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GFGFMMDL_00294 3.15e-277 dnaB - - L ko:K03346 - ko00000,ko03032 Replication initiation and membrane attachment
GFGFMMDL_00295 1.53e-213 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
GFGFMMDL_00296 1.45e-314 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
GFGFMMDL_00297 1.28e-31 - - - - - - - -
GFGFMMDL_00298 2.52e-30 - - - - - - - -
GFGFMMDL_00299 8.61e-18 yrdC - - Q - - - isochorismatase
GFGFMMDL_00300 2.92e-36 yrdC - - Q - - - isochorismatase
GFGFMMDL_00301 4.78e-110 - - - L ko:K07497 - ko00000 Integrase core domain protein
GFGFMMDL_00302 3.13e-95 - - - L - - - Transposase
GFGFMMDL_00303 7.01e-305 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GFGFMMDL_00304 1.52e-81 manO - - S - - - protein conserved in bacteria
GFGFMMDL_00305 2.02e-215 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose fructose sorbose family IID component
GFGFMMDL_00306 8.07e-160 manM - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 pts system
GFGFMMDL_00307 5.66e-231 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
GFGFMMDL_00308 3.05e-180 XK27_00940 3.5.1.9 - S ko:K07130 ko00380,ko00630,ko01100,map00380,map00630,map01100 ko00000,ko00001,ko00002,ko01000 Metal-dependent hydrolase
GFGFMMDL_00309 8.43e-196 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
GFGFMMDL_00310 2.53e-304 XK27_07275 - - S ko:K06901 - ko00000,ko02000 permease
GFGFMMDL_00311 1.54e-101 ydiB - - M ko:K06925 - ko00000,ko03016 ATPase or kinase
GFGFMMDL_00312 1.11e-118 - - - M - - - Acetyltransferase GNAT Family
GFGFMMDL_00313 1.68e-276 brpA - - K - - - Transcriptional
GFGFMMDL_00314 4.35e-105 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
GFGFMMDL_00315 2.28e-270 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
GFGFMMDL_00316 6.68e-64 ylxR - - K ko:K07742 - ko00000 Nucleic-acid-binding protein implicated in transcription termination
GFGFMMDL_00317 2.19e-56 ylxQ - - J - - - ribosomal protein
GFGFMMDL_00318 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GFGFMMDL_00319 9.81e-77 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GFGFMMDL_00320 1.12e-76 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
GFGFMMDL_00321 7.46e-297 femA 2.3.2.17 - V ko:K11694 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01011 protein involved in methicillin resistance
GFGFMMDL_00322 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GFGFMMDL_00323 0.0 ytgP - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
GFGFMMDL_00324 5.54e-101 pacL - - P - - - cation transport ATPase
GFGFMMDL_00325 2.4e-256 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
GFGFMMDL_00326 2.68e-284 malY 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
GFGFMMDL_00328 5.84e-13 sacB 2.4.1.10, 2.4.1.9 GH68 G ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 Belongs to the glycosyl hydrolase 68 family
GFGFMMDL_00329 1.06e-145 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GFGFMMDL_00330 2.64e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
GFGFMMDL_00331 1.58e-95 ylbF - - S - - - Belongs to the UPF0342 family
GFGFMMDL_00332 4.33e-62 ylbG - - S - - - UPF0298 protein
GFGFMMDL_00333 1.87e-269 livJ - - E ko:K01999 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
GFGFMMDL_00334 3.33e-189 livH - - E ko:K01997 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
GFGFMMDL_00335 7.76e-183 livM - - E ko:K01998 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
GFGFMMDL_00336 3.96e-177 livG - - E ko:K01995 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
GFGFMMDL_00337 3.1e-156 livF - - E ko:K01996 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
GFGFMMDL_00338 4.67e-90 acuB - - S ko:K04767 - ko00000 IMP dehydrogenase activity
GFGFMMDL_00339 1.25e-56 acuB - - S ko:K04767 - ko00000 IMP dehydrogenase activity
GFGFMMDL_00340 2.63e-214 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
GFGFMMDL_00341 3.86e-143 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
GFGFMMDL_00342 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GFGFMMDL_00343 1.89e-154 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
GFGFMMDL_00344 7.65e-119 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GFGFMMDL_00351 2.85e-214 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
GFGFMMDL_00352 1.85e-285 B4168_4126 - - L ko:K07493 - ko00000 Transposase
GFGFMMDL_00353 1.05e-139 - - - S - - - Domain of unknown function (DUF1803)
GFGFMMDL_00354 9.83e-133 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
GFGFMMDL_00355 2.2e-176 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
GFGFMMDL_00356 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GFGFMMDL_00357 1.26e-243 asnA 6.3.1.1 - E ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
GFGFMMDL_00358 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
GFGFMMDL_00359 2.07e-149 - - - S - - - Haloacid dehalogenase-like hydrolase
GFGFMMDL_00360 4.1e-179 phaB 5.3.3.14, 5.3.3.18 - I ko:K15866,ko:K18474 ko00061,ko00360,ko01120,map00061,map00360,map01120 ko00000,ko00001,ko01000,ko01004 Belongs to the enoyl-CoA hydratase isomerase family
GFGFMMDL_00361 5.39e-96 XK27_02735 - - K - - - Transcriptional regulator, MarR family
GFGFMMDL_00362 1.88e-224 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GFGFMMDL_00363 1.49e-40 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
GFGFMMDL_00364 2.65e-220 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 2-Nitropropane dioxygenase
GFGFMMDL_00365 5.5e-210 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
GFGFMMDL_00366 2.76e-163 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
GFGFMMDL_00367 2.9e-294 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
GFGFMMDL_00368 5.36e-84 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
GFGFMMDL_00369 3.98e-92 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
GFGFMMDL_00370 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
GFGFMMDL_00371 1.71e-204 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GFGFMMDL_00372 2.68e-176 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
GFGFMMDL_00373 6.58e-116 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
GFGFMMDL_00374 3.7e-154 - - - L ko:K07498 - ko00000 Transposase
GFGFMMDL_00375 7.7e-312 rny - - D ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
GFGFMMDL_00376 1.1e-155 fruR - - K ko:K03436 - ko00000,ko03000 transcriptional
GFGFMMDL_00377 1.85e-211 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
GFGFMMDL_00378 0.0 fruA 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GFGFMMDL_00379 0.0 gor 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GFGFMMDL_00380 1.26e-308 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
GFGFMMDL_00381 1.8e-06 - - - - - - - -
GFGFMMDL_00382 5.78e-268 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
GFGFMMDL_00383 5.31e-284 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GFGFMMDL_00384 0.0 gtf1 - - M - - - An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
GFGFMMDL_00385 0.0 gtf2 - - M - - - A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
GFGFMMDL_00386 6.44e-50 - 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 acetyltransferase
GFGFMMDL_00387 1.13e-37 - 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 acetyltransferase
GFGFMMDL_00388 2.83e-64 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
GFGFMMDL_00389 1.55e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
GFGFMMDL_00390 4.68e-27 ydaF_2 - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GFGFMMDL_00391 3.85e-65 ydaF_2 - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GFGFMMDL_00392 2.74e-84 WQ51_03320 - - S - - - cog cog4835
GFGFMMDL_00393 2.01e-183 - - - S - - - EDD domain protein, DegV family
GFGFMMDL_00394 2.48e-176 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
GFGFMMDL_00395 1.08e-285 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GFGFMMDL_00396 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 abc transporter atp-binding protein
GFGFMMDL_00398 2.43e-171 - - - F - - - AdP-ribose pyrophosphatase
GFGFMMDL_00399 1.75e-83 nadR - - H - - - adenylyltransferase
GFGFMMDL_00400 8.73e-153 nadR - - H - - - adenylyltransferase
GFGFMMDL_00401 0.0 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
GFGFMMDL_00402 1.3e-90 def_1 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
GFGFMMDL_00403 7.31e-100 - - - K - - - DNA-binding transcription factor activity
GFGFMMDL_00404 0.0 lmrA1 - - V ko:K02021,ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
GFGFMMDL_00405 0.0 lmrA2 - - V ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
GFGFMMDL_00406 7.57e-57 - - - K - - - Acetyltransferase (GNAT) family
GFGFMMDL_00407 2.14e-99 sptS - - T - - - Histidine kinase
GFGFMMDL_00408 1.61e-167 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
GFGFMMDL_00409 9.6e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
GFGFMMDL_00410 1.67e-206 yitL - - S ko:K00243 - ko00000 Protein conserved in bacteria
GFGFMMDL_00411 3.3e-47 yozE - - S - - - Belongs to the UPF0346 family
GFGFMMDL_00412 7.24e-173 usp 3.5.1.104, 3.5.1.28 CBM50 S ko:K15125,ko:K17733,ko:K21449,ko:K21471,ko:K22278,ko:K22409 ko05133,map05133 ko00000,ko00001,ko00536,ko01000,ko01002,ko01011,ko02000 pathogenesis
GFGFMMDL_00413 1.17e-58 sip - - M - - - LysM domain protein
GFGFMMDL_00414 4.56e-244 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
GFGFMMDL_00418 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GFGFMMDL_00419 3.09e-212 - - - K - - - transcriptional regulator (lysR family)
GFGFMMDL_00420 5.49e-237 coiA - - S ko:K06198 - ko00000 Competence protein
GFGFMMDL_00421 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
GFGFMMDL_00422 9.74e-164 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-Methyltransferase
GFGFMMDL_00423 1.16e-223 prsA 3.1.3.16, 5.2.1.8 - O ko:K01802,ko:K03769,ko:K07533,ko:K20074 - ko00000,ko01000,ko01009,ko03110 peptidyl-prolyl cis-trans isomerase activity
GFGFMMDL_00424 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GFGFMMDL_00425 2.28e-29 - - - M - - - GBS Bsp-like repeat
GFGFMMDL_00426 7.98e-230 - - - M - - - GBS Bsp-like repeat
GFGFMMDL_00427 6.71e-70 - 3.4.17.14, 3.5.1.28 - NU ko:K01448,ko:K02395,ko:K07260 ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036 amidase activity
GFGFMMDL_00428 3.78e-38 - 3.4.17.14, 3.5.1.28 - NU ko:K01448,ko:K02395,ko:K07260 ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036 amidase activity
GFGFMMDL_00429 8.16e-66 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
GFGFMMDL_00430 1.69e-92 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
GFGFMMDL_00431 4.75e-289 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 mutations do not affect methionine salvage in vivo however
GFGFMMDL_00432 3.9e-243 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GFGFMMDL_00433 5.38e-272 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GFGFMMDL_00434 2.98e-163 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
GFGFMMDL_00435 8.83e-265 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
GFGFMMDL_00436 3.18e-187 icaB - - G - - - deacetylase
GFGFMMDL_00437 5.73e-301 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
GFGFMMDL_00438 1.5e-197 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
GFGFMMDL_00439 1.88e-195 rarD - - S ko:K05786 - ko00000,ko02000 Transporter
GFGFMMDL_00441 2.62e-17 coiA - - S ko:K06198 - ko00000 Competence protein
GFGFMMDL_00442 2.44e-135 - - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GFGFMMDL_00443 1.46e-97 - 2.3.1.128, 5.2.1.8 - J ko:K03768,ko:K03790 - ko00000,ko01000,ko03009,ko03110 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GFGFMMDL_00444 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
GFGFMMDL_00445 2.91e-23 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GFGFMMDL_00446 7.36e-159 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
GFGFMMDL_00447 1.7e-100 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 ATP synthase F(0) sector subunit b
GFGFMMDL_00448 1.05e-114 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GFGFMMDL_00449 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GFGFMMDL_00450 3.7e-201 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GFGFMMDL_00451 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GFGFMMDL_00452 2.97e-77 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
GFGFMMDL_00453 1.57e-12 - - - L ko:K07485 - ko00000 Transposase
GFGFMMDL_00454 4.77e-291 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
GFGFMMDL_00455 1.59e-285 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GFGFMMDL_00456 3.8e-174 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GFGFMMDL_00457 1.19e-142 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GFGFMMDL_00458 1.92e-207 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 dna polymerase iii
GFGFMMDL_00459 1.07e-172 yaaT - - S - - - stage 0 sporulation protein
GFGFMMDL_00460 2.84e-73 yabA - - L - - - Involved in initiation control of chromosome replication
GFGFMMDL_00461 9.87e-204 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GFGFMMDL_00462 3.76e-286 amt - - P ko:K03320 - ko00000,ko02000 Ammonium Transporter
GFGFMMDL_00463 2.98e-67 glnB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
GFGFMMDL_00464 3.1e-138 mur1 - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 mannosyl-glycoprotein
GFGFMMDL_00465 1.28e-187 XK27_04800 - - S - - - Sucrose-6F-phosphate phosphohydrolase
GFGFMMDL_00466 2.24e-143 yjbB - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
GFGFMMDL_00467 4e-280 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
GFGFMMDL_00468 1.68e-15 - - - S - - - membrane
GFGFMMDL_00469 9.48e-58 - - - - - - - -
GFGFMMDL_00470 1.8e-79 - - - - - - - -
GFGFMMDL_00471 9.65e-79 - - - S - - - membrane
GFGFMMDL_00472 2.38e-224 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
GFGFMMDL_00473 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
GFGFMMDL_00474 1.42e-52 ynzC - - S - - - UPF0291 protein
GFGFMMDL_00475 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 permease
GFGFMMDL_00477 3.72e-29 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
GFGFMMDL_00478 3.85e-18 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
GFGFMMDL_00479 3.01e-32 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
GFGFMMDL_00480 5.29e-42 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
GFGFMMDL_00481 6e-93 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
GFGFMMDL_00482 2.29e-64 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
GFGFMMDL_00483 6.12e-180 ppiA 5.2.1.8 - O ko:K01802,ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 ko00000,ko00001,ko01000,ko03110,ko04147 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GFGFMMDL_00487 4.06e-214 lysR - - K - - - transcriptional regulator (lysR family)
GFGFMMDL_00488 4.01e-100 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GFGFMMDL_00489 4.03e-207 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
GFGFMMDL_00490 2.72e-114 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GFGFMMDL_00491 2.02e-288 pyrP - - F ko:K02824 - ko00000,ko02000 uracil Permease
GFGFMMDL_00492 8.28e-222 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
GFGFMMDL_00493 7.9e-270 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 carbamoyl-phosphate synthetase glutamine chain
GFGFMMDL_00494 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 carbamoyl-phosphate synthetase ammonia chain
GFGFMMDL_00495 2.68e-174 - - - S - - - Putative SAM-dependent methyltransferase
GFGFMMDL_00496 2.29e-36 yknX - - M ko:K02005 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GFGFMMDL_00497 4.22e-20 - - - V ko:K02004 - ko00000,ko00002,ko02000 permease protein
GFGFMMDL_00498 1.1e-46 - - - V - - - efflux transmembrane transporter activity
GFGFMMDL_00499 1.07e-44 - - - V ko:K02004 - ko00000,ko00002,ko02000 efflux transmembrane transporter activity
GFGFMMDL_00500 4.02e-38 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 efflux transmembrane transporter activity
GFGFMMDL_00501 4e-100 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GFGFMMDL_00502 7.29e-70 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
GFGFMMDL_00503 1.83e-141 - - - L ko:K07485 - ko00000 Transposase
GFGFMMDL_00504 5.4e-110 - - - - - - - -
GFGFMMDL_00505 1.25e-23 - - - L - - - Integrase core domain
GFGFMMDL_00506 1.62e-152 - - - V ko:K02003 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
GFGFMMDL_00507 9.49e-223 hrtB - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
GFGFMMDL_00510 1.65e-127 - - - S - - - MucBP domain
GFGFMMDL_00511 7.31e-61 - - - M - - - YSIRK type signal peptide
GFGFMMDL_00512 4.17e-317 - - - M - - - the current gene model (or a revised gene model) may contain a
GFGFMMDL_00513 7.86e-199 - - - M - - - the current gene model (or a revised gene model) may contain a
GFGFMMDL_00515 5.35e-36 XK27_00530 - - M - - - CHAP domain protein
GFGFMMDL_00516 3.3e-133 - - - K - - - Transcriptional regulator, AbiEi antitoxin
GFGFMMDL_00517 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
GFGFMMDL_00518 5.12e-38 - - - K ko:K02051 - ko00000,ko00002,ko02000 DNA-binding transcription factor activity
GFGFMMDL_00519 0.0 msbA_1 - - V ko:K18887 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
GFGFMMDL_00520 0.0 lmrA - - V ko:K06147,ko:K18888 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
GFGFMMDL_00521 4.81e-252 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GFGFMMDL_00522 3.65e-158 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
GFGFMMDL_00523 2.37e-251 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
GFGFMMDL_00524 3.25e-40 XK27_00085 - - K ko:K07729 - ko00000,ko03000 Transcriptional
GFGFMMDL_00526 2.2e-175 - - - F - - - Phosphorylase superfamily
GFGFMMDL_00527 5.99e-145 - - - S - - - VIT family
GFGFMMDL_00528 3.96e-165 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
GFGFMMDL_00529 4.82e-276 hipO2 - - E ko:K01436,ko:K21613 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
GFGFMMDL_00530 1.29e-24 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 alanine dehydrogenase activity
GFGFMMDL_00531 1.36e-58 ald 1.4.1.1 - C ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
GFGFMMDL_00532 4.75e-316 merA - - C - - - Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GFGFMMDL_00533 2.11e-132 - - - J ko:K09962 - ko00000 protein conserved in bacteria
GFGFMMDL_00534 1.51e-184 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
GFGFMMDL_00535 2.66e-221 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
GFGFMMDL_00536 3.88e-218 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 GHMP kinases N terminal domain
GFGFMMDL_00537 3.75e-243 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
GFGFMMDL_00538 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GFGFMMDL_00539 8.64e-125 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 AdP-ribose pyrophosphatase
GFGFMMDL_00540 8.53e-41 - - - - - - - -
GFGFMMDL_00541 2.1e-151 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GFGFMMDL_00543 3.42e-35 - - - M ko:K02460 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02044 domain protein
GFGFMMDL_00544 2.55e-81 - - - M ko:K02460 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02044 domain protein
GFGFMMDL_00545 8.17e-242 dgs 2.4.1.208 GT4 M ko:K13677 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
GFGFMMDL_00546 0.0 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
GFGFMMDL_00547 1.7e-65 - - - - - - - -
GFGFMMDL_00548 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GFGFMMDL_00549 7.9e-218 - - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
GFGFMMDL_00550 9.19e-209 - - - S - - - Protein of unknown function (DUF3114)
GFGFMMDL_00551 9.03e-29 - - - S - - - Protein of unknown function (DUF3114)
GFGFMMDL_00552 4.28e-153 hly-III - - K ko:K11068 - ko00000,ko02042 protein, Hemolysin III
GFGFMMDL_00553 8.02e-294 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
GFGFMMDL_00554 1.28e-278 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 synthase
GFGFMMDL_00555 5.15e-214 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GFGFMMDL_00556 7.3e-121 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GFGFMMDL_00557 2.97e-30 - - - - - - - -
GFGFMMDL_00558 4.22e-286 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GFGFMMDL_00559 6.75e-144 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
GFGFMMDL_00560 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
GFGFMMDL_00561 1.8e-226 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 Homocysteine
GFGFMMDL_00562 5.22e-41 - - - S - - - Domain of unknown function (DUF1912)
GFGFMMDL_00563 7.76e-21 - - - L - - - Helix-hairpin-helix DNA-binding motif class 1
GFGFMMDL_00564 8.62e-138 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
GFGFMMDL_00565 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GFGFMMDL_00566 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GFGFMMDL_00567 1.75e-255 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
GFGFMMDL_00568 1.4e-21 - - - S - - - Protein of unknown function (DUF2969)
GFGFMMDL_00571 5.85e-268 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 ribosomal protein S1
GFGFMMDL_00574 6.33e-132 - - - S - - - Domain of Unknown Function with PDB structure (DUF3862)
GFGFMMDL_00575 1.37e-87 - - - M - - - Pfam SNARE associated Golgi protein
GFGFMMDL_00576 1.28e-293 murN - - V ko:K12554 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01011 FemAB family
GFGFMMDL_00577 4.44e-06 - - - S - - - oxidoreductase
GFGFMMDL_00578 2.19e-47 - - - S - - - oxidoreductase
GFGFMMDL_00579 1.25e-129 - - - S - - - oxidoreductase
GFGFMMDL_00580 5.47e-66 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
GFGFMMDL_00581 1.86e-74 XK27_09440 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
GFGFMMDL_00582 6.87e-22 XK27_09440 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
GFGFMMDL_00583 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
GFGFMMDL_00584 8.72e-233 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GFGFMMDL_00585 1.15e-47 ykuJ - - S - - - protein conserved in bacteria
GFGFMMDL_00586 3.24e-151 - - - P ko:K02029 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GFGFMMDL_00587 4.45e-169 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 abc transporter atp-binding protein
GFGFMMDL_00588 3.01e-102 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain protein
GFGFMMDL_00589 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
GFGFMMDL_00590 9.87e-12 - - - - - - - -
GFGFMMDL_00591 2.87e-47 yugF - - I - - - carboxylic ester hydrolase activity
GFGFMMDL_00592 4.53e-30 - - - I - - - Alpha/beta hydrolase family
GFGFMMDL_00593 4.19e-203 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GFGFMMDL_00594 1.01e-191 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GFGFMMDL_00595 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 penicillin-binding protein
GFGFMMDL_00596 2.16e-135 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GFGFMMDL_00597 1.74e-57 licT - - K ko:K02538,ko:K03488 - ko00000,ko03000 transcriptional antiterminator
GFGFMMDL_00598 3.52e-84 licT - - K ko:K03488 - ko00000,ko03000 antiterminator
GFGFMMDL_00599 6.25e-112 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GFGFMMDL_00600 1.41e-84 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
GFGFMMDL_00601 1.16e-212 era - - M ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GFGFMMDL_00602 1.16e-199 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
GFGFMMDL_00603 1.09e-136 coaE 2.7.1.24 - H ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GFGFMMDL_00604 4e-279 pmrA - - EGP ko:K08161 - ko00000,ko02000 Major Facilitator
GFGFMMDL_00605 1.5e-44 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
GFGFMMDL_00606 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
GFGFMMDL_00607 5.69e-105 smpB - - O ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
GFGFMMDL_00608 0.0 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GFGFMMDL_00609 1.08e-84 yugI - - J ko:K07570 - ko00000 RNA binding protein, contains ribosomal protein S1 domain
GFGFMMDL_00610 6.72e-266 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Belongs to the peptidase M24B family
GFGFMMDL_00611 1.34e-235 ccpA - - K ko:K02529 - ko00000,ko03000 Catabolite control protein A
GFGFMMDL_00612 4.17e-16 XK27_07735 - - S - - - YjbR
GFGFMMDL_00613 2.6e-182 XK27_07735 - - S - - - YjbR
GFGFMMDL_00614 1.75e-56 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
GFGFMMDL_00615 3.07e-174 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
GFGFMMDL_00616 4.34e-94 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
GFGFMMDL_00617 5.04e-314 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
GFGFMMDL_00619 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
GFGFMMDL_00620 3.56e-281 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
GFGFMMDL_00621 5.43e-156 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
GFGFMMDL_00622 1.72e-207 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GFGFMMDL_00623 1.62e-254 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GFGFMMDL_00624 1.29e-279 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GFGFMMDL_00625 1.58e-263 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
GFGFMMDL_00626 1.48e-71 XK26_04240 - - S - - - Belongs to the UPF0342 family
GFGFMMDL_00627 1.88e-222 hicD2 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
GFGFMMDL_00628 1.7e-297 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
GFGFMMDL_00629 2.28e-113 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GFGFMMDL_00630 6.93e-197 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
GFGFMMDL_00631 0.0 msrR - - K - - - Transcriptional regulator
GFGFMMDL_00632 4.07e-199 ydiA - - P ko:K03304,ko:K11041 ko05150,map05150 ko00000,ko00001,ko02000,ko02042 C4-dicarboxylate transporter malic acid transport protein
GFGFMMDL_00633 4.47e-256 - - - I - - - acyl-CoA dehydrogenase
GFGFMMDL_00634 5.21e-126 mip - - S - - - hydroperoxide reductase activity
GFGFMMDL_00635 0.0 rumA 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GFGFMMDL_00636 9.57e-117 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
GFGFMMDL_00637 1.08e-121 - - - - - - - -
GFGFMMDL_00638 5.12e-51 - - - L ko:K07483 - ko00000 transposase activity
GFGFMMDL_00639 2.65e-87 - - - L ko:K07497 - ko00000 COG2801 Transposase and inactivated derivatives
GFGFMMDL_00640 4.19e-92 - - - L ko:K07497 - ko00000 COG2801 Transposase and inactivated derivatives
GFGFMMDL_00642 1.22e-10 - - - M - - - Bacterial lipoprotein
GFGFMMDL_00643 2.2e-77 - - - S - - - Protein of unknown function (DUF1722)
GFGFMMDL_00644 2.38e-83 yqeB - - S - - - Pyrimidine dimer DNA glycosylase
GFGFMMDL_00646 2.51e-44 - - - - - - - -
GFGFMMDL_00647 7.8e-35 - - - S - - - CAAX protease self-immunity
GFGFMMDL_00648 4.48e-35 - - - E - - - GDSL-like Lipase/Acylhydrolase
GFGFMMDL_00649 1.79e-123 - - - - - - - -
GFGFMMDL_00650 0.0 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
GFGFMMDL_00651 9.3e-221 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GFGFMMDL_00652 2.94e-71 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GFGFMMDL_00653 2.37e-249 - - - S - - - CRISPR-associated protein Csn2 subfamily St
GFGFMMDL_00654 5.66e-190 XK27_03010 - - S ko:K08986 - ko00000 TIGR03943 family
GFGFMMDL_00655 7.34e-196 XK27_03015 - - S ko:K07089 - ko00000 permease
GFGFMMDL_00657 0.0 tex - - K ko:K06959 - ko00000 Transcriptional accessory protein
GFGFMMDL_00658 3.44e-54 WQ51_05770 - - KT - - - PspC domain
GFGFMMDL_00659 1.17e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GFGFMMDL_00660 1.51e-190 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GFGFMMDL_00661 1.14e-26 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GFGFMMDL_00662 9.59e-91 ytxH - - S - - - General stress protein
GFGFMMDL_00664 2.05e-227 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
GFGFMMDL_00665 0.0 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
GFGFMMDL_00666 3.62e-60 - - - S - - - CHY zinc finger
GFGFMMDL_00667 2.67e-113 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 biotin synthase
GFGFMMDL_00669 2.97e-45 XK27_12190 - - S - - - protein conserved in bacteria
GFGFMMDL_00670 1.57e-297 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
GFGFMMDL_00671 3.85e-88 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
GFGFMMDL_00672 0.0 - - - L - - - helicase
GFGFMMDL_00673 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
GFGFMMDL_00674 2.51e-200 - - - M - - - LysM domain
GFGFMMDL_00675 7.61e-30 - - - - - - - -
GFGFMMDL_00676 6.31e-222 - - - S ko:K07025 - ko00000 hydrolase
GFGFMMDL_00677 1.02e-149 pgm - - G - - - Phosphoglycerate mutase
GFGFMMDL_00678 2.49e-105 - - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GFGFMMDL_00679 1.91e-194 - 3.5.1.28 - M ko:K01447,ko:K07273 - ko00000,ko01000 Glycosyl hydrolase, family 25
GFGFMMDL_00680 1.14e-35 - - - P - - - Hemerythrin HHE cation binding domain protein
GFGFMMDL_00681 2.32e-144 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GFGFMMDL_00682 4.51e-14 - - - S - - - Protein of unknown function (DUF2974)
GFGFMMDL_00683 1.43e-44 - - - S - - - Protein of unknown function (DUF2974)
GFGFMMDL_00684 3.7e-51 sdh - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
GFGFMMDL_00685 0.0 - - - V - - - Type I restriction enzyme R protein N terminus (HSDR_N)
GFGFMMDL_00686 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 N-6 DNA Methylase
GFGFMMDL_00687 4.68e-188 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain protein
GFGFMMDL_00688 8.79e-234 - - - S - - - AAA domain
GFGFMMDL_00689 6.76e-63 - - - S - - - PD-(D/E)XK nuclease family transposase
GFGFMMDL_00690 6.57e-113 - - - S - - - double-stranded DNA endodeoxyribonuclease activity
GFGFMMDL_00691 4.21e-118 lemA - - S ko:K03744 - ko00000 LemA family
GFGFMMDL_00692 1.9e-184 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
GFGFMMDL_00693 8.61e-97 - - - S ko:K16927 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score
GFGFMMDL_00694 8.87e-73 - - - S - - - Domain of unknown function (DUF4430)
GFGFMMDL_00695 0.0 ppc 4.1.1.31 - H ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GFGFMMDL_00696 3.69e-234 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
GFGFMMDL_00697 6.73e-145 sodA 1.15.1.1 - C ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
GFGFMMDL_00698 1.31e-166 - - - L ko:K07485 - ko00000 Transposase
GFGFMMDL_00701 1.12e-33 crpB - - Q - - - the current gene model (or a revised gene model) may contain a frame shift
GFGFMMDL_00702 6.09e-39 crpB - - Q - - - the current gene model (or a revised gene model) may contain a frame shift
GFGFMMDL_00703 5.6e-17 - - - S - - - Domain of unknown function (DUF4649)
GFGFMMDL_00704 3.25e-227 - - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter substrate binding protein
GFGFMMDL_00705 1.95e-190 XK27_08840 - - S ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
GFGFMMDL_00706 1.09e-173 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
GFGFMMDL_00707 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GFGFMMDL_00708 5.93e-191 estA - CE1 S ko:K03930 - ko00000,ko01000 Putative esterase
GFGFMMDL_00709 1.27e-161 XK27_08875 - - O - - - Zinc-dependent metalloprotease
GFGFMMDL_00711 8.21e-97 ykuP - - C ko:K03839 - ko00000 Flavodoxin
GFGFMMDL_00712 0.0 eriC - - P ko:K03281 - ko00000 Chloride transporter, ClC family
GFGFMMDL_00713 1.27e-55 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 - E ko:K00661,ko:K04092,ko:K04093,ko:K04516,ko:K14170,ko:K14187 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Chorismate mutase
GFGFMMDL_00714 1.97e-261 eriC - - P ko:K03281 - ko00000 Chloride transporter ClC family
GFGFMMDL_00715 2.33e-74 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
GFGFMMDL_00717 1.17e-105 - - - - - - - -
GFGFMMDL_00718 9.42e-28 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
GFGFMMDL_00719 5.62e-209 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GFGFMMDL_00720 6.46e-116 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
GFGFMMDL_00721 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GFGFMMDL_00722 4.6e-221 birA 6.3.4.15 - HK ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
GFGFMMDL_00723 6.14e-258 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GFGFMMDL_00724 0.0 - 5.1.3.2 - GM ko:K01784,ko:K21009 ko00052,ko00520,ko01100,ko02025,map00052,map00520,map01100,map02025 ko00000,ko00001,ko00002,ko01000 Psort location CytoplasmicMembrane, score
GFGFMMDL_00725 1.78e-213 - - - - - - - -
GFGFMMDL_00726 0.0 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2194)
GFGFMMDL_00727 0.0 - 2.4.1.52 GT4 M ko:K00712,ko:K21011 ko02025,map02025 ko00000,ko00001,ko01000,ko01003 Domain of unknown function (DUF3492)
GFGFMMDL_00728 4.44e-242 - - - M ko:K21012 ko02025,map02025 ko00000,ko00001 Putative exopolysaccharide Exporter (EPS-E)
GFGFMMDL_00729 4.56e-269 - - - M ko:K06330 - ko00000 CotH kinase protein
GFGFMMDL_00730 7e-60 - - - P - - - VTC domain
GFGFMMDL_00731 2.46e-43 - - - P - - - VTC domain
GFGFMMDL_00732 1.02e-161 - - - G - - - Domain of unknown function (DUF4832)
GFGFMMDL_00733 6.05e-250 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
GFGFMMDL_00735 1.01e-295 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GFGFMMDL_00736 4.09e-35 - - - S - - - DNA-directed RNA polymerase subunit beta
GFGFMMDL_00737 3.68e-181 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
GFGFMMDL_00738 2.48e-143 - - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
GFGFMMDL_00739 3.24e-156 XK27_07620 - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
GFGFMMDL_00740 4.65e-192 peb1A - - ET ko:K02030,ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type amino acid transport signal transduction systems, periplasmic component domain
GFGFMMDL_00741 2.21e-179 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
GFGFMMDL_00742 4.13e-165 yycF - - KT ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GFGFMMDL_00743 5.5e-315 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GFGFMMDL_00744 3.43e-195 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Metal-dependent hydrolases of the beta-lactamase superfamily I
GFGFMMDL_00746 3.51e-292 femX 2.3.2.10, 2.3.2.16 - V ko:K05363,ko:K11693 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01011 protein involved in methicillin resistance
GFGFMMDL_00747 2.3e-188 XK27_00835 - - S - - - hydrolases of the HAD superfamily
GFGFMMDL_00748 8.41e-105 XK27_00115 - - K - - - Acetyltransferase GNAT family
GFGFMMDL_00749 1.19e-89 ywiB - - S - - - Domain of unknown function (DUF1934)
GFGFMMDL_00750 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 cation transport ATPase
GFGFMMDL_00751 3.26e-173 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
GFGFMMDL_00752 2.13e-231 - - - S - - - Calcineurin-like phosphoesterase
GFGFMMDL_00753 4.87e-260 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GFGFMMDL_00754 1.53e-231 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GFGFMMDL_00755 2.35e-156 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
GFGFMMDL_00756 1.99e-209 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
GFGFMMDL_00757 6.84e-118 mutX 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NTP pyrophosphohydrolases including oxidative damage repair enzymes
GFGFMMDL_00758 3.5e-231 XK27_05220 - - S - - - permease
GFGFMMDL_00759 5.23e-283 XK27_05225 - - G - - - COG0457 FOG TPR repeat
GFGFMMDL_00760 7.34e-123 sipC 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
GFGFMMDL_00761 2.36e-287 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
GFGFMMDL_00762 4.4e-117 ebsA - - S - - - Family of unknown function (DUF5322)
GFGFMMDL_00763 8.18e-43 XK27_09115 - - M - - - LysM domain
GFGFMMDL_00764 3.39e-155 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
GFGFMMDL_00765 4.47e-115 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GFGFMMDL_00766 2.77e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
GFGFMMDL_00767 1.82e-73 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GFGFMMDL_00768 1.15e-39 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 rRNA binding
GFGFMMDL_00769 5.82e-221 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
GFGFMMDL_00770 1.78e-133 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase small domain protein
GFGFMMDL_00771 2.18e-32 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
GFGFMMDL_00772 5.3e-33 pdp 2.4.2.2, 2.4.2.4 - F ko:K00756,ko:K00758 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 ko00000,ko00001,ko01000 phosphorylase activity
GFGFMMDL_00773 4.56e-123 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
GFGFMMDL_00774 4.03e-39 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GFGFMMDL_00775 1.8e-81 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GFGFMMDL_00776 1.95e-90 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
GFGFMMDL_00777 6.71e-243 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
GFGFMMDL_00778 0.0 mglA 3.6.3.17 - S ko:K02056,ko:K06400 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GFGFMMDL_00779 5.56e-246 mglC - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
GFGFMMDL_00780 2.35e-217 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
GFGFMMDL_00781 4.36e-155 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
GFGFMMDL_00782 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
GFGFMMDL_00783 1.32e-106 ypmB - - S - - - Protein conserved in bacteria
GFGFMMDL_00784 3.16e-278 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
GFGFMMDL_00785 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
GFGFMMDL_00787 3.04e-40 - - - - - - - -
GFGFMMDL_00788 1.84e-83 aldR 3.5.99.10 - J ko:K09022 - ko00000,ko01000 endoribonuclease L-PSP
GFGFMMDL_00789 1.52e-158 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GFGFMMDL_00790 4.76e-105 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
GFGFMMDL_00791 4.15e-171 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
GFGFMMDL_00792 3.87e-122 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
GFGFMMDL_00793 5.92e-23 - - - D - - - nuclear chromosome segregation
GFGFMMDL_00794 1.73e-172 yejC - - S - - - cyclic nucleotide-binding protein
GFGFMMDL_00795 1.2e-208 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
GFGFMMDL_00796 1.44e-230 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
GFGFMMDL_00797 9.84e-207 whiA - - K ko:K09762 - ko00000 May be required for sporulation
GFGFMMDL_00798 1.74e-130 pepD - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
GFGFMMDL_00799 6.4e-55 pepD - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
GFGFMMDL_00800 1.56e-38 - - - L ko:K07483 - ko00000 transposase activity
GFGFMMDL_00802 9.64e-38 - - - - - - - -
GFGFMMDL_00803 6.22e-43 - - - K - - - Cold shock protein domain
GFGFMMDL_00804 3.06e-56 cspA - - K ko:K03704 - ko00000,ko03000 Cold-Shock Protein
GFGFMMDL_00805 0.0 copB 3.6.3.4 - P ko:K01533 - ko00000,ko01000 P-type ATPase
GFGFMMDL_00806 1.03e-188 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
GFGFMMDL_00807 9.92e-18 B4168_4126 - - L ko:K07493 - ko00000 Transposase
GFGFMMDL_00808 4.02e-186 glcU - - U ko:K05340 - ko00000,ko02000 sugar transport
GFGFMMDL_00809 1.34e-144 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
GFGFMMDL_00810 1.76e-196 - - - - - - - -
GFGFMMDL_00811 5.81e-41 - - - L - - - Phage integrase family
GFGFMMDL_00812 9.29e-73 - - - L - - - Phage integrase family
GFGFMMDL_00813 2.51e-144 - - - - - - - -
GFGFMMDL_00816 1.28e-71 pepD - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
GFGFMMDL_00817 1.69e-128 XK27_10720 - - D - - - peptidase activity
GFGFMMDL_00818 0.0 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
GFGFMMDL_00821 3.88e-220 yeiH - - S - - - Membrane
GFGFMMDL_00822 1.07e-152 - - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 muramidase
GFGFMMDL_00823 1.31e-26 - - - L ko:K07483 - ko00000 transposase activity
GFGFMMDL_00824 6.46e-91 - - - L ko:K07497 - ko00000 transposition
GFGFMMDL_00825 8.86e-214 cpsY - - K - - - Transcriptional regulator
GFGFMMDL_00826 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
GFGFMMDL_00827 4.47e-76 phnA - - P ko:K06193 ko01120,map01120 ko00000 Alkylphosphonate utilization operon protein PhnA
GFGFMMDL_00828 1.17e-135 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter (Permease
GFGFMMDL_00829 4.34e-145 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 abc transporter atp-binding protein
GFGFMMDL_00830 7.82e-203 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
GFGFMMDL_00831 3.92e-91 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GFGFMMDL_00832 2.99e-137 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GFGFMMDL_00833 2.18e-10 - - - - - - - -
GFGFMMDL_00834 1.55e-79 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
GFGFMMDL_00835 5.85e-142 adhP 1.1.1.1 - C ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
GFGFMMDL_00837 6.93e-28 - - - - - - - -
GFGFMMDL_00838 0.0 sthIR 3.1.21.5 - S ko:K01156 - ko00000,ko01000,ko02048 Type III restriction
GFGFMMDL_00839 2.05e-259 - 2.1.1.72 - L ko:K07316 - ko00000,ko01000,ko02048 DNA methylase
GFGFMMDL_00840 6.38e-146 - 2.1.1.72 - L ko:K07316 - ko00000,ko01000,ko02048 Adenine specific DNA methylase Mod
GFGFMMDL_00841 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
GFGFMMDL_00842 6.09e-161 yvoA_2 - - K ko:K03710 - ko00000,ko03000 transcriptional
GFGFMMDL_00843 1.49e-70 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GFGFMMDL_00844 0.0 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GFGFMMDL_00845 3.33e-102 niaX - - - ko:K16788 - ko00000,ko02000 -
GFGFMMDL_00846 6.35e-212 - - - S - - - Phage integrase family
GFGFMMDL_00847 3.18e-48 - - - S - - - Host cell surface-exposed lipoprotein
GFGFMMDL_00848 7.82e-56 - - - E - - - Zn peptidase
GFGFMMDL_00849 9.56e-83 - - - S - - - sequence-specific DNA binding
GFGFMMDL_00851 2.94e-138 - - - S - - - DNA binding
GFGFMMDL_00854 1.21e-09 - - - K - - - Cro/C1-type HTH DNA-binding domain
GFGFMMDL_00857 2.8e-19 - - - S - - - Hypothetical protein (DUF2513)
GFGFMMDL_00859 1.39e-39 - - - S - - - transferase activity
GFGFMMDL_00860 1.12e-160 - - - S - - - Replication initiator protein A (RepA) N-terminus
GFGFMMDL_00861 5.08e-167 - - - S - - - IstB-like ATP binding protein
GFGFMMDL_00863 2.62e-83 - - - S - - - DNA metabolic process
GFGFMMDL_00864 4.63e-65 - - - S - - - Protein of unknown function (DUF1351)
GFGFMMDL_00865 3.33e-92 - - - S - - - Single-strand binding protein family
GFGFMMDL_00866 1.64e-59 rusA - - L - - - holliday junction resolvase
GFGFMMDL_00868 4.47e-17 - - - - - - - -
GFGFMMDL_00873 5.56e-37 - - - S - - - Protein of unknown function (DUF1642)
GFGFMMDL_00874 7.1e-100 - - - S - - - sequence-specific DNA binding
GFGFMMDL_00878 1.22e-07 - - - S - - - YopX protein
GFGFMMDL_00879 0.000151 - - - - - - - -
GFGFMMDL_00881 4.27e-41 - - - - - - - -
GFGFMMDL_00882 3.11e-30 - - - L ko:K07474 - ko00000 DNA packaging
GFGFMMDL_00883 2.02e-153 - - - S - - - Terminase-like family
GFGFMMDL_00884 1.09e-132 - - - S - - - Terminase-like family
GFGFMMDL_00885 0.0 - - - S - - - Phage portal protein, SPP1 Gp6-like
GFGFMMDL_00886 9.24e-193 - - - S - - - Phage Mu protein F like protein
GFGFMMDL_00887 9.78e-31 - - - S - - - Domain of unknown function (DUF4355)
GFGFMMDL_00889 3.31e-239 - - - S - - - Phage major capsid protein E
GFGFMMDL_00891 1.33e-43 - - - S - - - Phage gp6-like head-tail connector protein
GFGFMMDL_00893 1.16e-64 - - - S - - - exonuclease activity
GFGFMMDL_00894 7.33e-83 - - - S - - - Protein of unknown function (DUF3168)
GFGFMMDL_00895 2.95e-112 - - - S - - - Phage major tail protein 2
GFGFMMDL_00896 8.07e-76 - - - S - - - Pfam:Phage_TAC_12
GFGFMMDL_00898 0.0 - - - S - - - peptidoglycan catabolic process
GFGFMMDL_00899 3.18e-214 - - - S - - - Phage tail protein
GFGFMMDL_00900 1.79e-173 - - - S - - - peptidoglycan catabolic process
GFGFMMDL_00901 0.0 - - - S - - - peptidoglycan catabolic process
GFGFMMDL_00902 5.9e-275 - - - S - - - N-acetylmuramoyl-L-alanine amidase activity
GFGFMMDL_00906 2.77e-29 hol - - S - - - COG5546 Small integral membrane protein
GFGFMMDL_00907 8.71e-133 - - - M - - - Bacteriophage peptidoglycan hydrolase
GFGFMMDL_00908 1.32e-60 - - - S - - - Streptococcus thermophilus bacteriophage Gp111 protein
GFGFMMDL_00911 1.25e-114 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
GFGFMMDL_00912 2.47e-165 - - - K - - - DNA-binding helix-turn-helix protein
GFGFMMDL_00913 5.95e-203 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GFGFMMDL_00914 7.94e-173 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GFGFMMDL_00915 7.29e-215 - - - GK - - - ROK family
GFGFMMDL_00916 9.91e-204 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
GFGFMMDL_00917 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GFGFMMDL_00918 7.22e-199 - - - S - - - TraX protein
GFGFMMDL_00919 4.87e-156 spaR - - KT ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GFGFMMDL_00920 2.07e-304 - 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
GFGFMMDL_00921 0.0 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GFGFMMDL_00922 2.65e-105 XK27_05470 - - E - - - Methionine synthase
GFGFMMDL_00923 4.23e-44 XK27_05470 - - E - - - Methionine synthase
GFGFMMDL_00924 1.01e-99 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
GFGFMMDL_00925 3.23e-59 pspE - - P ko:K03972 - ko00000 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GFGFMMDL_00926 7.4e-70 butA 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 Acetoin reductase
GFGFMMDL_00927 5.43e-56 butA 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 Acetoin reductase
GFGFMMDL_00929 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
GFGFMMDL_00932 1.04e-70 - - - K ko:K15773 - ko00000,ko02048,ko03000 peptidyl-tyrosine sulfation
GFGFMMDL_00933 3.68e-13 - - - L - - - Integrase core domain protein
GFGFMMDL_00934 1.02e-199 - - - K - - - Transcriptional activator, Rgg GadR MutR family
GFGFMMDL_00937 3.68e-271 nirJ - - C ko:K06139,ko:K22227 - ko00000 radical SAM domain protein
GFGFMMDL_00938 3.15e-175 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
GFGFMMDL_00939 6.38e-75 - - - EGP ko:K08218 ko01501,map01501 ko00000,ko00001,ko00002,ko02000 Major facilitator Superfamily
GFGFMMDL_00940 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
GFGFMMDL_00941 1.24e-43 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
GFGFMMDL_00942 1.34e-172 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Belongs to the alpha-acetolactate decarboxylase family
GFGFMMDL_00943 4.85e-115 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (Permease
GFGFMMDL_00944 1.5e-139 - - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
GFGFMMDL_00945 2.64e-14 - - - - - - - -
GFGFMMDL_00946 4.46e-126 - - - K - - - Transcriptional regulator, TetR family
GFGFMMDL_00947 1.29e-204 czcD - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
GFGFMMDL_00948 3.77e-265 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
GFGFMMDL_00949 2.78e-250 adhB 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Dehydrogenase
GFGFMMDL_00950 2.92e-11 - - - S ko:K06889 - ko00000 Hydrolases of the alpha beta superfamily
GFGFMMDL_00951 3.95e-24 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
GFGFMMDL_00952 4.07e-45 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
GFGFMMDL_00953 6.44e-44 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
GFGFMMDL_00956 5.46e-184 - - - F - - - Phosphorylase superfamily
GFGFMMDL_00957 1.71e-152 - 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 HAD hydrolase, family IA, variant 1
GFGFMMDL_00958 9.2e-25 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type enterochelin transport system, periplasmic component
GFGFMMDL_00959 3.07e-90 dinF - - V - - - Mate efflux family protein
GFGFMMDL_00960 8.1e-19 dinF - - V - - - Mate efflux family protein
GFGFMMDL_00962 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
GFGFMMDL_00963 0.000353 - - - S - - - TraX protein
GFGFMMDL_00964 6.99e-65 - - - S - - - TraX protein
GFGFMMDL_00965 3.38e-122 thiJ 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1 family
GFGFMMDL_00967 6.61e-187 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
GFGFMMDL_00968 7.98e-225 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
GFGFMMDL_00969 8.4e-235 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GFGFMMDL_00970 2.91e-72 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GFGFMMDL_00971 3.78e-88 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
GFGFMMDL_00972 1.15e-300 - - - M ko:K20345 ko02024,map02024 ko00000,ko00001,ko02000 HlyD family secretion protein
GFGFMMDL_00973 0.0 comA - - V ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
GFGFMMDL_00977 2.51e-62 - - - S - - - Enterocin A Immunity
GFGFMMDL_00982 7.27e-06 - - - S - - - Bacteriocin class II with double-glycine leader peptide
GFGFMMDL_00983 2.19e-71 ps105 - - - - - - -
GFGFMMDL_00985 2.82e-20 - - - - ko:K20341 ko02024,map02024 ko00000,ko00001 -
GFGFMMDL_00986 3.59e-211 blpT - - - - - - -
GFGFMMDL_00988 2.59e-171 agrA - - KT ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 phosphorelay signal transduction system
GFGFMMDL_00989 3.65e-178 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
GFGFMMDL_00992 2.32e-63 - - - S - - - Psort location Cytoplasmic, score
GFGFMMDL_00993 1.26e-137 - - - S - - - Psort location Cytoplasmic, score
GFGFMMDL_00994 9.75e-162 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
GFGFMMDL_00995 4.34e-145 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GFGFMMDL_00996 6.74e-11 nylA 3.5.1.4 - J ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 amidase activity
GFGFMMDL_00997 7.71e-64 nylA 3.5.1.4 - J ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 Belongs to the amidase family
GFGFMMDL_00999 0.0 dtpT - - E ko:K03305 - ko00000 transporter
GFGFMMDL_01000 3.62e-106 nylA 3.5.1.4 - J ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 Belongs to the amidase family
GFGFMMDL_01001 1.36e-121 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
GFGFMMDL_01002 1.38e-63 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
GFGFMMDL_01003 8.73e-30 yecS - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 amino acid transport
GFGFMMDL_01005 2.67e-306 sasH 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
GFGFMMDL_01006 7.69e-72 sasH 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
GFGFMMDL_01007 1.32e-87 yfiF3 - - K - - - sequence-specific DNA binding
GFGFMMDL_01008 1.16e-29 bglC - - K - - - Transcriptional regulator
GFGFMMDL_01009 1.46e-315 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GFGFMMDL_01010 5.81e-306 agcS - - E ko:K03310 - ko00000 (Alanine) symporter
GFGFMMDL_01011 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
GFGFMMDL_01012 1.91e-303 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 o-acetylhomoserine
GFGFMMDL_01013 1.47e-166 - - - S - - - haloacid dehalogenase-like hydrolase
GFGFMMDL_01014 4.76e-111 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GFGFMMDL_01015 1.91e-142 hsdS2 - - V - - - Type I restriction modification DNA specificity domain
GFGFMMDL_01016 1.7e-45 M1-755 - - P ko:K09155 - ko00000 Hemerythrin HHE cation binding domain protein
GFGFMMDL_01017 5.79e-34 XK27_04775 - - S ko:K09155 - ko00000 hemerythrin HHE cation binding domain
GFGFMMDL_01018 2.23e-59 XK27_04775 - - S ko:K09155 - ko00000 hemerythrin HHE cation binding domain
GFGFMMDL_01019 4.02e-193 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GFGFMMDL_01020 3.95e-222 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
GFGFMMDL_01021 7.23e-93 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
GFGFMMDL_01022 3.43e-59 yktA - - S - - - Belongs to the UPF0223 family
GFGFMMDL_01023 5.9e-184 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
GFGFMMDL_01024 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
GFGFMMDL_01025 5.92e-202 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 phosphate
GFGFMMDL_01026 1.55e-199 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
GFGFMMDL_01027 2.05e-199 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 phosphate transport system permease
GFGFMMDL_01028 1.24e-191 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GFGFMMDL_01029 7.15e-179 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GFGFMMDL_01030 7.71e-148 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
GFGFMMDL_01031 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
GFGFMMDL_01032 1.88e-249 xerS - - D ko:K04763 - ko00000,ko03036 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
GFGFMMDL_01033 2.82e-235 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
GFGFMMDL_01034 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
GFGFMMDL_01035 0.0 malQ 2.4.1.25 GH77 G ko:K00705 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 4-alpha-glucanotransferase
GFGFMMDL_01036 3.42e-66 malR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
GFGFMMDL_01037 8.48e-269 malX - - G ko:K15770 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GFGFMMDL_01038 5.95e-301 malF - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
GFGFMMDL_01039 5.86e-191 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
GFGFMMDL_01040 2.66e-251 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GFGFMMDL_01041 1.32e-229 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type enterochelin transport system, periplasmic component
GFGFMMDL_01042 1.75e-174 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
GFGFMMDL_01043 6.34e-214 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GFGFMMDL_01044 7.78e-211 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GFGFMMDL_01045 1.33e-40 pulA2 3.2.1.1, 3.2.1.41 CBM48,GH13 G ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
GFGFMMDL_01046 3.89e-107 pulA2 3.2.1.1, 3.2.1.41 CBM48,GH13 G ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
GFGFMMDL_01047 8.06e-70 pulA2 3.2.1.1, 3.2.1.41 CBM48,GH13 G ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
GFGFMMDL_01048 5.02e-253 pulA2 3.2.1.1, 3.2.1.41 CBM48,GH13 G ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
GFGFMMDL_01049 1.43e-97 - 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 GBS Bsp-like repeat
GFGFMMDL_01050 1.03e-73 - 3.5.1.28 - S ko:K01448,ko:K02395,ko:K21471 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko02035,ko03036 dextransucrase activity
GFGFMMDL_01051 1.17e-35 - 3.5.1.28 - S ko:K01448,ko:K02395,ko:K21471 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko02035,ko03036 dextransucrase activity
GFGFMMDL_01052 1.21e-65 - 3.5.1.28 - S ko:K01448,ko:K02395,ko:K21471 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko02035,ko03036 dextransucrase activity
GFGFMMDL_01053 8.73e-86 - 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 GBS Bsp-like repeat
GFGFMMDL_01054 0.0 lpdA 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
GFGFMMDL_01055 2.47e-274 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
GFGFMMDL_01056 3.38e-232 acoB 1.2.4.1 - C ko:K00162,ko:K21417 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
GFGFMMDL_01057 3.57e-235 acoA 1.2.4.1 - C ko:K00161,ko:K21416 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
GFGFMMDL_01058 0.0 - - - S - - - the current gene model (or a revised gene model) may contain a frame shift
GFGFMMDL_01059 1.63e-297 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
GFGFMMDL_01060 1.92e-161 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GFGFMMDL_01061 2.22e-276 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GFGFMMDL_01062 7.23e-30 dacA1 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
GFGFMMDL_01063 3.33e-107 dacA1 3.4.16.4 - M ko:K01286 - ko00000,ko01000 Belongs to the peptidase S11 family
GFGFMMDL_01064 4.3e-98 dacA1 3.4.16.4 - M ko:K01286 - ko00000,ko01000 Belongs to the peptidase S11 family
GFGFMMDL_01065 2.06e-198 - - - S - - - Phospholipase, patatin family
GFGFMMDL_01066 1.7e-138 - - - E - - - Lysophospholipase L1 and related esterases
GFGFMMDL_01067 0.0 ubiB - - S ko:K03688 - ko00000 unusual protein kinase
GFGFMMDL_01068 5.54e-51 - - - S - - - granule-associated protein
GFGFMMDL_01069 4.88e-49 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
GFGFMMDL_01070 6.88e-58 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 beta-glucosidase activity
GFGFMMDL_01071 1.98e-126 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
GFGFMMDL_01072 3.29e-22 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
GFGFMMDL_01073 2.38e-254 XK27_12525 - - S - - - hmm pf01594
GFGFMMDL_01074 1.13e-75 - - - G - - - Belongs to the phosphoglycerate mutase family
GFGFMMDL_01075 1.04e-29 - - - G - - - Belongs to the phosphoglycerate mutase family
GFGFMMDL_01076 1.15e-42 - - - G - - - Belongs to the phosphoglycerate mutase family
GFGFMMDL_01077 9.91e-124 - - - V - - - VanZ like family
GFGFMMDL_01078 3.66e-292 - - - L ko:K07485 - ko00000 Transposase
GFGFMMDL_01079 1.13e-247 - - - M - - - transferase activity, transferring glycosyl groups
GFGFMMDL_01080 5.34e-222 wefC - - M - - - Stealth protein CR2, conserved region 2
GFGFMMDL_01081 3.01e-276 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
GFGFMMDL_01082 2.27e-306 wzx - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
GFGFMMDL_01083 2.38e-213 - - - - - - - -
GFGFMMDL_01084 2.74e-93 - - - M - - - Glycosyltransferase like family 2
GFGFMMDL_01085 6.79e-154 - - - M - - - Glycosyltransferase, group 2 family protein
GFGFMMDL_01086 2.08e-149 - - - G - - - Glycosyltransferase Family 4
GFGFMMDL_01087 2.61e-280 rgpAc - GT4 M ko:K12996 - ko00000,ko01000,ko01003,ko01005 group 1 family protein
GFGFMMDL_01088 0.0 cpsE - - M - - - Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
GFGFMMDL_01089 4.49e-154 cpsD - - D - - - COG0489 ATPases involved in chromosome partitioning
GFGFMMDL_01090 3.89e-147 capA - - M - - - biosynthesis protein
GFGFMMDL_01091 6.62e-175 cpsB 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 Capsular polysaccharide biosynthesis protein
GFGFMMDL_01092 0.0 cps4A - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
GFGFMMDL_01093 3.27e-167 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 purine nucleoside phosphorylase
GFGFMMDL_01094 4.77e-122 gat 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 glutamine amidotransferase
GFGFMMDL_01095 1.02e-191 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GFGFMMDL_01096 2.19e-53 - - - S - - - Protein of unknown function (DUF1697)
GFGFMMDL_01097 1.1e-299 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
GFGFMMDL_01098 2.91e-156 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GFGFMMDL_01099 3.87e-10 B4168_4126 - - L ko:K07493 - ko00000 Transposase
GFGFMMDL_01100 6.71e-12 - - - V - - - Glucan-binding protein C
GFGFMMDL_01102 1.54e-142 ung2 - - L - - - Uracil-DNA glycosylase
GFGFMMDL_01103 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Dipeptidase
GFGFMMDL_01104 2.78e-37 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
GFGFMMDL_01105 7.73e-109 XK27_03610 - - K - - - Gnat family
GFGFMMDL_01106 5.05e-152 ciaH 2.7.13.3 - T ko:K14982 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GFGFMMDL_01107 4.9e-53 ciaH 2.7.13.3 - T ko:K14982 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GFGFMMDL_01108 8.96e-150 ciaR - - T ko:K14983 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GFGFMMDL_01109 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
GFGFMMDL_01110 1.56e-156 coaB 6.3.2.5 - H ko:K21977 ko00770,map00770 ko00000,ko00001,ko00002,ko01000 Phosphopantothenate-cysteine ligase
GFGFMMDL_01111 4.28e-120 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GFGFMMDL_01112 2.62e-121 - - - S - - - ECF transporter, substrate-specific component
GFGFMMDL_01113 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
GFGFMMDL_01114 2.18e-211 metF 1.5.1.20 - C ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 reductase
GFGFMMDL_01115 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GFGFMMDL_01117 0.0 pabB 2.6.1.85, 4.1.3.38 - EH ko:K01665,ko:K03342,ko:K13950 ko00790,map00790 ko00000,ko00001,ko01000,ko01007 component I
GFGFMMDL_01118 0.0 - 3.6.3.2, 3.6.3.6, 3.6.3.8 - P ko:K01531,ko:K01535,ko:K01537 ko00190,map00190 ko00000,ko00001,ko01000 cation transport ATPase
GFGFMMDL_01119 1.27e-51 - - - L ko:K07483 - ko00000 Transposase
GFGFMMDL_01120 2.8e-23 - - - L ko:K07483 - ko00000 transposase activity
GFGFMMDL_01121 6.18e-107 - - - L ko:K07497 - ko00000 Transposase and inactivated derivatives
GFGFMMDL_01122 7.41e-294 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GFGFMMDL_01123 2.03e-47 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GFGFMMDL_01124 6.93e-300 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Membrane protein involved in D-alanine export
GFGFMMDL_01125 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GFGFMMDL_01126 3.08e-14 - - - S - - - D-Ala-teichoic acid biosynthesis protein
GFGFMMDL_01127 0.0 XK27_10035 - - V ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
GFGFMMDL_01128 0.0 yfiB1 - - V ko:K06147,ko:K06148 - ko00000,ko02000 abc transporter atp-binding protein
GFGFMMDL_01129 5.44e-129 pvaA - - M ko:K02395 - ko00000,ko02035 lytic transglycosylase activity
GFGFMMDL_01130 5.59e-224 - - - S - - - 37-kD nucleoid-associated bacterial protein
GFGFMMDL_01131 2.4e-296 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GFGFMMDL_01132 1.46e-139 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
GFGFMMDL_01133 4.65e-192 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
GFGFMMDL_01134 1.86e-246 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GFGFMMDL_01135 4.93e-141 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
GFGFMMDL_01136 2.62e-239 add 3.5.4.2, 3.5.4.4 - F ko:K01488,ko:K02029,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GFGFMMDL_01137 1.11e-196 gst - - O ko:K11209 - ko00000,ko01000 Glutathione S-transferase
GFGFMMDL_01138 2.9e-225 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 domain protein
GFGFMMDL_01139 4.75e-218 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
GFGFMMDL_01140 5.46e-59 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 50S ribosomal protein L31
GFGFMMDL_01141 7.25e-284 mntH_2 - - P - - - Mn2 and Fe2 transporters of the NRAMP family
GFGFMMDL_01142 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GFGFMMDL_01143 5.7e-184 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division protein DivIVA
GFGFMMDL_01144 1.38e-183 ylmH - - T ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 S4 RNA-binding domain
GFGFMMDL_01145 1.8e-46 yggT - - D ko:K02221 - ko00000,ko02044 integral membrane protein
GFGFMMDL_01146 4.05e-122 sepF - - D ko:K09772 - ko00000,ko03036 cell septum assembly
GFGFMMDL_01147 4.65e-158 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GFGFMMDL_01148 7.57e-303 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GFGFMMDL_01149 0.0 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
GFGFMMDL_01150 5.31e-233 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
GFGFMMDL_01151 4.3e-255 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GFGFMMDL_01152 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GFGFMMDL_01153 2.68e-12 - - - S - - - Protein of unknown function (DUF3165)
GFGFMMDL_01154 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
GFGFMMDL_01155 6.85e-228 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
GFGFMMDL_01156 1.58e-37 yqgQ - - S - - - protein conserved in bacteria
GFGFMMDL_01157 1.95e-103 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
GFGFMMDL_01158 9.8e-113 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
GFGFMMDL_01159 1.51e-148 pppA 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
GFGFMMDL_01160 1.79e-290 - - - V - - - D-alanyl-D-alanine carboxypeptidase
GFGFMMDL_01161 3.19e-302 - - - L ko:K07485 - ko00000 Transposase
GFGFMMDL_01162 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
GFGFMMDL_01163 3.89e-235 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
GFGFMMDL_01164 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
GFGFMMDL_01165 1.99e-194 XK27_00020 - - J - - - Belongs to the SUA5 family
GFGFMMDL_01166 2.76e-146 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GFGFMMDL_01167 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GFGFMMDL_01168 1.64e-57 ysdA - - L - - - Membrane
GFGFMMDL_01169 7.51e-242 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
GFGFMMDL_01170 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GFGFMMDL_01171 3.05e-169 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GFGFMMDL_01172 6.62e-230 pyrD 1.3.5.2, 1.3.98.1 - F ko:K00226,ko:K00254 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dihydroorotate to orotate
GFGFMMDL_01174 1.54e-52 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
GFGFMMDL_01175 5.99e-124 ypmS - - S - - - Protein conserved in bacteria
GFGFMMDL_01176 2.86e-183 ypmR - - E - - - lipolytic protein G-D-S-L family
GFGFMMDL_01177 1.96e-189 WQ51_01275 - - S - - - DegV family
GFGFMMDL_01178 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
GFGFMMDL_01179 5.12e-96 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
GFGFMMDL_01180 7.78e-201 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
GFGFMMDL_01181 2.72e-202 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
GFGFMMDL_01182 1.72e-40 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease VII activity
GFGFMMDL_01183 7.45e-313 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GFGFMMDL_01186 3.81e-154 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GFGFMMDL_01187 8.66e-161 dnaD - - - ko:K02086 - ko00000 -
GFGFMMDL_01188 8.4e-234 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GFGFMMDL_01189 1.3e-121 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GFGFMMDL_01190 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease recj
GFGFMMDL_01191 5.21e-178 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
GFGFMMDL_01192 4.43e-222 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
GFGFMMDL_01193 3.17e-149 XK27_05445 - - G - - - UDPglucose--hexose-1-phosphate uridylyltransferase
GFGFMMDL_01194 2.35e-285 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GFGFMMDL_01195 3.24e-308 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
GFGFMMDL_01196 1.48e-65 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 - E ko:K01523,ko:K01814,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 phosphoribosyl-ATP diphosphatase activity
GFGFMMDL_01197 6.01e-80 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GFGFMMDL_01198 5.63e-176 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
GFGFMMDL_01199 1.75e-168 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GFGFMMDL_01200 3.88e-140 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GFGFMMDL_01201 3.35e-137 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
GFGFMMDL_01202 2.41e-297 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GFGFMMDL_01203 6.62e-148 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
GFGFMMDL_01204 1.76e-232 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GFGFMMDL_01205 5.82e-250 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GFGFMMDL_01207 4.41e-108 - - - L ko:K07497 - ko00000 Transposase and inactivated derivatives
GFGFMMDL_01208 5.46e-52 XK27_08080 - - G - - - Exopolysaccharide biosynthesis protein
GFGFMMDL_01209 1.69e-34 XK27_08080 - - G - - - Exopolysaccharide biosynthesis protein
GFGFMMDL_01210 8.31e-14 XK27_08080 - - G - - - Exopolysaccharide biosynthesis protein
GFGFMMDL_01211 1.39e-180 hisJ 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Histidinol phosphatase and related hydrolases of the PHP family
GFGFMMDL_01212 1.15e-156 - - - S - - - tigr01906
GFGFMMDL_01213 6.89e-184 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
GFGFMMDL_01214 3.17e-184 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
GFGFMMDL_01215 6.59e-277 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
GFGFMMDL_01219 1.35e-263 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
GFGFMMDL_01220 8.22e-144 rmlC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
GFGFMMDL_01221 2.62e-204 rfbA 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GFGFMMDL_01222 6.9e-261 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 oxidoreductase
GFGFMMDL_01223 7.34e-91 zupT - - P ko:K07238 - ko00000,ko02000 Mediates zinc uptake. May also transport other divalent cations
GFGFMMDL_01224 3.79e-28 zupT - - P ko:K07238 - ko00000,ko02000 Mediates zinc uptake. May also transport other divalent cations
GFGFMMDL_01225 2.71e-188 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GFGFMMDL_01226 2.59e-160 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
GFGFMMDL_01227 8.21e-92 mesH - - S - - - GtrA-like protein
GFGFMMDL_01228 6.47e-316 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GFGFMMDL_01229 5.25e-211 ybbR - - S - - - Protein conserved in bacteria
GFGFMMDL_01230 1.74e-155 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GFGFMMDL_01231 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Mur ligase, middle domain protein
GFGFMMDL_01232 1.02e-192 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
GFGFMMDL_01233 0.0 mprF 2.3.2.3 - J ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GFGFMMDL_01234 6.11e-169 - 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Alpha beta hydrolase
GFGFMMDL_01236 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 abc transporter atp-binding protein
GFGFMMDL_01237 2.24e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
GFGFMMDL_01238 5.29e-242 yfmL - - L - - - DEAD DEAH box helicase
GFGFMMDL_01239 7.95e-37 - 6.3.2.2, 6.3.2.4 - F ko:K01919,ko:K01921 ko00270,ko00473,ko00480,ko00550,ko01100,ko01502,map00270,map00473,map00480,map00550,map01100,map01502 ko00000,ko00001,ko00002,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
GFGFMMDL_01240 0.0 gapN 1.2.1.9 - C ko:K00131 ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
GFGFMMDL_01241 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GFGFMMDL_01242 2.72e-51 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein Hpr
GFGFMMDL_01243 2.32e-279 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 Isocitrate dehydrogenase
GFGFMMDL_01244 6.04e-271 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
GFGFMMDL_01245 0.0 acnA 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GFGFMMDL_01246 1.61e-44 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
GFGFMMDL_01247 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GFGFMMDL_01248 8.44e-237 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GFGFMMDL_01249 7.14e-140 - - - L ko:K07497 - ko00000 EVIDENCE EXPERIMENTAL PMID 1328163 BIO14.04 Transposon related functions. BELONGS TO THE IS3 IS150 IS904 FAMILY OF TRANSPOSASE. There are 7 such elements in the chromosome
GFGFMMDL_01251 2.75e-74 - - - L - - - PFAM transposase IS116 IS110 IS902 family
GFGFMMDL_01252 1.96e-78 - - - L - - - Transposase (IS116 IS110 IS902 family)
GFGFMMDL_01253 1.39e-211 ypuA - - S - - - secreted protein
GFGFMMDL_01254 5.14e-168 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase (surface protein transpeptidase)
GFGFMMDL_01255 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GFGFMMDL_01256 3.41e-231 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
GFGFMMDL_01257 0.0 noxE - - P - - - NADH oxidase
GFGFMMDL_01258 0.0 yheS_1 - - S - - - abc transporter atp-binding protein
GFGFMMDL_01259 1.93e-78 - - - S - - - ECF-type riboflavin transporter, S component
GFGFMMDL_01260 8.01e-16 - - - S - - - ECF-type riboflavin transporter, S component
GFGFMMDL_01261 1.73e-40 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Belongs to the pyridoxine kinase family
GFGFMMDL_01262 2.83e-50 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Belongs to the pyridoxine kinase family
GFGFMMDL_01263 1.71e-111 - - - S - - - ECF-type riboflavin transporter, S component
GFGFMMDL_01265 1.03e-304 ycxD - - K - - - Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
GFGFMMDL_01266 5.37e-74 nrdD_1 1.1.98.6, 1.17.4.1 - F ko:K00525,ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Ribonucleoside-triphosphate reductase
GFGFMMDL_01269 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GFGFMMDL_01270 6.18e-120 XK27_03150 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GFGFMMDL_01271 5.02e-250 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GFGFMMDL_01272 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
GFGFMMDL_01273 7.55e-160 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
GFGFMMDL_01274 3.65e-222 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GFGFMMDL_01275 5.86e-254 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GFGFMMDL_01276 3.69e-53 alkD - - L - - - Dna alkylation repair
GFGFMMDL_01277 5.31e-120 pat 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 acetyltransferase
GFGFMMDL_01278 5.9e-140 - - - L ko:K07485 - ko00000 Transposase
GFGFMMDL_01279 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GFGFMMDL_01280 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
GFGFMMDL_01281 4.72e-154 yfnB 3.8.1.2 - E ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 hydrolase
GFGFMMDL_01282 4.93e-83 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 biotin transmembrane transporter activity
GFGFMMDL_01283 4.34e-122 - - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GFGFMMDL_01284 3.14e-177 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
GFGFMMDL_01285 7.87e-214 proWY - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, QAT family
GFGFMMDL_01286 1.46e-132 proWZ - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
GFGFMMDL_01287 4.73e-96 - 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
GFGFMMDL_01288 1.83e-239 - 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
GFGFMMDL_01289 2.6e-257 - - - S ko:K09703 - ko00000 Protein of unknown function (DUF917)
GFGFMMDL_01290 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GFGFMMDL_01291 6.89e-78 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
GFGFMMDL_01292 2.23e-129 desR - - K ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GFGFMMDL_01293 1.07e-243 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GFGFMMDL_01294 1.68e-169 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
GFGFMMDL_01295 2.52e-204 XK27_09825 - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
GFGFMMDL_01299 3.08e-268 - - - EGP - - - Major facilitator Superfamily
GFGFMMDL_01300 0.0 - 2.7.7.73, 2.7.7.80 - E ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 metalloendopeptidase activity
GFGFMMDL_01303 2e-124 - - - E - - - LysE type translocator
GFGFMMDL_01304 0.000117 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 AMP-binding enzyme
GFGFMMDL_01305 1.05e-54 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 AMP-binding enzyme C-terminal domain
GFGFMMDL_01306 0.000279 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 TIGRFAM amino acid adenylation domain
GFGFMMDL_01307 1.68e-60 - - - L ko:K07483 - ko00000 Transposase
GFGFMMDL_01308 1.42e-163 - - - L - - - Integrase core domain protein
GFGFMMDL_01309 1.43e-227 - 2.7.7.73, 2.7.7.80 - E ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 metalloendopeptidase activity
GFGFMMDL_01310 1.05e-195 mutR - - K - - - Transcriptional activator, Rgg GadR MutR family
GFGFMMDL_01311 3.03e-55 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
GFGFMMDL_01313 1.77e-158 - - - S - - - An automated process has identified a potential problem with this gene model
GFGFMMDL_01314 1.69e-31 XK27_09825 - - V ko:K01990 - ko00000,ko00002,ko02000 'abc transporter, ATP-binding protein
GFGFMMDL_01317 1.17e-120 XK27_05000 - - S ko:K06940 - ko00000 metal cluster binding
GFGFMMDL_01318 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
GFGFMMDL_01319 7.36e-172 yxdL - - V ko:K02003,ko:K19083 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
GFGFMMDL_01320 1.3e-217 - - - T - - - Histidine kinase
GFGFMMDL_01321 3.03e-158 graR - - KT ko:K19082 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GFGFMMDL_01322 8.62e-101 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
GFGFMMDL_01323 7.11e-147 pbuX - - F ko:K16169 - ko00000,ko02000 xanthine permease
GFGFMMDL_01324 6.46e-57 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
GFGFMMDL_01325 1.85e-316 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
GFGFMMDL_01326 1.35e-239 msrA 1.8.4.11, 1.8.4.12 - O ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GFGFMMDL_01327 4.69e-298 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
GFGFMMDL_01328 9.41e-87 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
GFGFMMDL_01329 4.42e-73 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
GFGFMMDL_01330 6.68e-35 csbD - - K - - - CsbD-like
GFGFMMDL_01331 4.6e-294 yfnA - - E ko:K03294 - ko00000 amino acid
GFGFMMDL_01332 3.89e-139 XK27_02070 - - S ko:K07078 - ko00000 nitroreductase
GFGFMMDL_01333 6.42e-184 catE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
GFGFMMDL_01334 6.99e-99 ywnA_2 - - K - - - Transcriptional regulator
GFGFMMDL_01335 1.84e-203 - - - E - - - Alpha/beta hydrolase of unknown function (DUF915)
GFGFMMDL_01336 4.42e-290 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GFGFMMDL_01337 8.21e-143 ydgI - - C - - - Nitroreductase
GFGFMMDL_01338 1.21e-116 - - - S - - - Protein of unknown function (DUF1275)
GFGFMMDL_01339 2.26e-05 - - - S - - - Protein of unknown function (DUF1275)
GFGFMMDL_01340 2.63e-204 yvgN - - C - - - reductase
GFGFMMDL_01341 1.7e-225 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
GFGFMMDL_01342 0.0 XK27_07020 - - S - - - Belongs to the UPF0371 family
GFGFMMDL_01344 4.53e-50 BP1961 - - P - - - nitric oxide dioxygenase activity
GFGFMMDL_01345 1.46e-69 saeR - - K ko:K10682 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
GFGFMMDL_01346 1.64e-85 - - - S - - - Signal peptide protein, YSIRK family
GFGFMMDL_01347 1.44e-79 - - - - - - - -
GFGFMMDL_01348 0.0 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GFGFMMDL_01349 8.68e-188 - - - - - - - -
GFGFMMDL_01351 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
GFGFMMDL_01352 9.13e-113 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
GFGFMMDL_01353 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 Type I restriction-modification system
GFGFMMDL_01354 0.0 - - - M - - - family 8
GFGFMMDL_01355 5.12e-51 - - - L ko:K07483 - ko00000 transposase activity
GFGFMMDL_01356 2.45e-109 - - - L ko:K07497 - ko00000 transposition
GFGFMMDL_01357 3.79e-217 - - - EGP - - - Major Facilitator Superfamily
GFGFMMDL_01358 0.0 - - - I - - - radical SAM domain protein
GFGFMMDL_01360 7.24e-205 - - - K - - - Transcriptional activator, Rgg GadR MutR family
GFGFMMDL_01361 1.67e-164 - - - L ko:K07497 - ko00000 Integrase core domain protein
GFGFMMDL_01362 7.65e-89 - - - L ko:K07483 - ko00000 transposase activity
GFGFMMDL_01364 2.36e-110 - - - - - - - -
GFGFMMDL_01365 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 ATPase involved in DNA repair
GFGFMMDL_01366 1.53e-291 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
GFGFMMDL_01367 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 -beta-galactosidase
GFGFMMDL_01368 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 transporter
GFGFMMDL_01369 2.21e-253 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
GFGFMMDL_01370 2.02e-246 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
GFGFMMDL_01371 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDPglucose--hexose-1-phosphate uridylyltransferase
GFGFMMDL_01372 5.62e-274 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GFGFMMDL_01373 7.76e-234 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
GFGFMMDL_01374 1.7e-13 - - - L ko:K07497 - ko00000 Integrase core domain protein
GFGFMMDL_01375 3.37e-34 - - - L ko:K07497 - ko00000 transposition
GFGFMMDL_01376 0.0 zmpB - - M ko:K08643 - ko00000,ko01000,ko01002 M26 IgA1-specific Metallo-endopeptidase C-terminal region
GFGFMMDL_01377 4.19e-124 ndvA - - V ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
GFGFMMDL_01378 5.1e-38 - - - V ko:K18996,ko:K19171 - ko00000,ko02048,ko03032 (ABC) transporter
GFGFMMDL_01379 0.0 gshF 6.3.2.2 - H ko:K01919,ko:K16786,ko:K16787 ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the glutamate--cysteine ligase type 1 family
GFGFMMDL_01380 1.02e-99 - - - L - - - Transposase
GFGFMMDL_01381 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
GFGFMMDL_01382 1.35e-239 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
GFGFMMDL_01383 5.68e-174 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
GFGFMMDL_01384 6.44e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GFGFMMDL_01387 8.07e-148 vraR - - K ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GFGFMMDL_01388 1.12e-224 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GFGFMMDL_01389 1.09e-154 yvqF - - KT ko:K11622 ko02020,map02020 ko00000,ko00001 membrane
GFGFMMDL_01390 2.51e-13 - - - L ko:K07485 - ko00000 Transposase
GFGFMMDL_01391 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
GFGFMMDL_01392 6.37e-169 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
GFGFMMDL_01393 2.82e-316 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GFGFMMDL_01394 1.55e-223 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GFGFMMDL_01395 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GFGFMMDL_01396 2.77e-61 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-directed 5'-3' RNA polymerase activity
GFGFMMDL_01397 3.57e-144 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
GFGFMMDL_01398 9.38e-311 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GFGFMMDL_01399 2.14e-192 XK27_02985 - - S - - - overlaps another CDS with the same product name
GFGFMMDL_01400 4.49e-188 - - - S - - - overlaps another CDS with the same product name
GFGFMMDL_01401 2.43e-83 ytrA - - K ko:K07979 - ko00000,ko03000 Transcriptional
GFGFMMDL_01402 2.38e-158 skfE - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
GFGFMMDL_01403 4.04e-169 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPase activity
GFGFMMDL_01404 3.46e-218 amiF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GFGFMMDL_01405 3.42e-259 amiE - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GFGFMMDL_01406 2.34e-212 amiD - - P ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
GFGFMMDL_01407 0.0 amiC - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
GFGFMMDL_01408 0.0 amiA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
GFGFMMDL_01409 8.58e-28 amiF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GFGFMMDL_01410 6.44e-50 tatD - - L ko:K03424 - ko00000,ko01000 Hydrolase, tatd
GFGFMMDL_01411 3.41e-277 oxlT - - P ko:K08177 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
GFGFMMDL_01412 4.4e-32 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
GFGFMMDL_01413 4.07e-80 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
GFGFMMDL_01414 1.37e-36 - - - L ko:K07497 - ko00000 transposition
GFGFMMDL_01415 1.33e-96 - - - L - - - Transposase
GFGFMMDL_01416 6.36e-231 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
GFGFMMDL_01417 4.44e-221 yjbO 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
GFGFMMDL_01418 2.21e-193 nadK 2.7.1.23 - H ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GFGFMMDL_01419 2.26e-151 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 Gtp pyrophosphokinase
GFGFMMDL_01420 6.42e-133 yjbK - - S - - - Adenylate cyclase
GFGFMMDL_01421 2.03e-225 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GFGFMMDL_01422 1.12e-264 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
GFGFMMDL_01423 1.77e-78 XK27_04120 - - S - - - Putative amino acid metabolism
GFGFMMDL_01424 4.52e-151 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GFGFMMDL_01425 1.32e-156 - - - T ko:K07010 - ko00000,ko01002 peptidase C26
GFGFMMDL_01426 2.79e-155 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
GFGFMMDL_01427 0.0 rgpF - - M ko:K07272 - ko00000,ko01000,ko01003,ko01005 Rhamnan synthesis protein F
GFGFMMDL_01428 3.44e-281 rgpD 3.6.3.40 - P ko:K01990,ko:K09691,ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
GFGFMMDL_01429 6.03e-179 - - - GM ko:K01992,ko:K09690,ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
GFGFMMDL_01430 4.6e-221 rgpB - GT2 M ko:K12997 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
GFGFMMDL_01431 5.07e-283 rgpA - GT4 M ko:K12996 - ko00000,ko01000,ko01003,ko01005 Domain of unknown function (DUF1972)
GFGFMMDL_01432 0.0 - - - S - - - Glucosyl transferase GtrII
GFGFMMDL_01433 5.02e-277 - - GT4 M ko:K00754 - ko00000,ko01000 transferase activity, transferring glycosyl groups
GFGFMMDL_01434 1.23e-275 - - - M - - - Psort location CytoplasmicMembrane, score
GFGFMMDL_01435 0.0 - - - M - - - Glycosyltransferase like family 2
GFGFMMDL_01436 6.43e-194 - - - S - - - Glycosyltransferase group 2 family protein
GFGFMMDL_01437 8e-57 - - - S ko:K09153 - ko00000 Uncharacterized conserved protein (DUF2304)
GFGFMMDL_01438 5.17e-164 arnC - - M ko:K00786 - ko00000,ko01000 group 2 family protein
GFGFMMDL_01439 1.84e-181 arbY - - M - - - Glycosyl transferase family 8
GFGFMMDL_01440 5.42e-209 rgpX3 - - S - - - polysaccharide biosynthetic process
GFGFMMDL_01441 7.76e-103 - - - S - - - Psort location CytoplasmicMembrane, score
GFGFMMDL_01442 2.34e-204 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
GFGFMMDL_01443 6.1e-193 - - - S - - - Glucosyl transferase GtrII
GFGFMMDL_01444 2.62e-117 - - - S - - - Glucosyl transferase GtrII
GFGFMMDL_01445 5.75e-213 yfdH - GT2 M ko:K12999,ko:K20534 - ko00000,ko01000,ko01003,ko01005,ko02000 COG0463, glycosyltransferases involved in cell wall biogenesis
GFGFMMDL_01446 4.86e-74 yitW - - K - - - metal-sulfur cluster biosynthetic enzyme
GFGFMMDL_01447 2.49e-256 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
GFGFMMDL_01448 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
GFGFMMDL_01449 1.14e-62 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
GFGFMMDL_01450 1.01e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
GFGFMMDL_01451 9.99e-176 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
GFGFMMDL_01452 1.85e-265 arcT - - E - - - Aminotransferase
GFGFMMDL_01453 5.98e-173 XK27_04395 - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter
GFGFMMDL_01454 5.96e-181 XK27_04395 - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
GFGFMMDL_01455 2.15e-109 XK27_04400 3.6.1.55 - F ko:K03574,ko:K12944 - ko00000,ko01000,ko03400 Nudix family
GFGFMMDL_01456 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
GFGFMMDL_01457 8.09e-73 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
GFGFMMDL_01458 5.12e-42 - - - S ko:K07052 - ko00000 CAAX amino terminal protease family protein
GFGFMMDL_01459 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type amino acid transport signal transduction systems periplasmic component domain
GFGFMMDL_01460 5.88e-175 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 abc transporter atp-binding protein
GFGFMMDL_01461 1.84e-24 XK27_00735 - - - - - - -
GFGFMMDL_01462 1.9e-316 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GFGFMMDL_01463 8.41e-11 - - - S - - - Protein of unknown function (DUF4044)
GFGFMMDL_01464 5.23e-172 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
GFGFMMDL_01466 1.46e-84 - - - Q ko:K02614 ko00360,map00360 ko00000,ko00001,ko01000 protein possibly involved in aromatic compounds catabolism
GFGFMMDL_01467 1.5e-68 ycaO - - O ko:K06889,ko:K07397,ko:K09136 - ko00000,ko03009 OsmC-like protein
GFGFMMDL_01469 1.55e-195 - - - EG - - - Permeases of the drug metabolite transporter (DMT) superfamily
GFGFMMDL_01471 7.16e-147 serB 3.1.3.3 - E ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01009 phosphoserine phosphatase
GFGFMMDL_01472 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GFGFMMDL_01473 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GFGFMMDL_01474 2.53e-140 - - - S - - - IA, variant 1
GFGFMMDL_01475 2.27e-151 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 effector of murein hydrolase
GFGFMMDL_01476 1.65e-76 lrgA - - S ko:K06518 - ko00000,ko02000 Effector of murein hydrolase LrgA
GFGFMMDL_01478 3.55e-79 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
GFGFMMDL_01479 4.23e-73 ogt 2.1.1.63, 3.2.2.20 - L ko:K00567,ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 methylated-DNA-[protein]-cysteine S-methyltransferase activity
GFGFMMDL_01480 2.61e-281 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GFGFMMDL_01481 1.33e-134 - - - M - - - Acetyltransferase (GNAT) domain
GFGFMMDL_01482 2.96e-266 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GFGFMMDL_01483 2.99e-59 - - - GK - - - ROK family
GFGFMMDL_01484 1.15e-92 - - - GK - - - ROK family
GFGFMMDL_01485 1.37e-92 gloA 4.4.1.5 - E ko:K01759,ko:K15772 ko00620,ko02010,map00620,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Lactoylglutathione lyase
GFGFMMDL_01486 1.37e-195 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 HflC and HflK could regulate a protease
GFGFMMDL_01487 3.44e-263 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 spermidine putrescine ABC transporter
GFGFMMDL_01488 5.13e-171 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type spermidine putrescine transport system, permease component II
GFGFMMDL_01489 5.72e-179 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type spermidine putrescine transport system, permease component I
GFGFMMDL_01490 1.38e-272 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
GFGFMMDL_01491 4.06e-219 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
GFGFMMDL_01492 7.94e-114 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GFGFMMDL_01493 1.49e-81 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GFGFMMDL_01494 0.0 amy 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
GFGFMMDL_01495 5.24e-188 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GFGFMMDL_01496 1.17e-129 folE 3.5.4.16 - F ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 gtp cyclohydrolase
GFGFMMDL_01497 0.0 ydaO - - E - - - amino acid
GFGFMMDL_01498 1.52e-301 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
GFGFMMDL_01499 9.09e-50 ylqC - - L ko:K06960 - ko00000 Belongs to the UPF0109 family
GFGFMMDL_01500 1.87e-57 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
GFGFMMDL_01501 2.56e-217 tehB 2.1.1.265 - PQ ko:K16868 - ko00000,ko01000 tellurite resistance protein tehb
GFGFMMDL_01503 2.84e-201 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
GFGFMMDL_01504 2.02e-96 - - - S - - - QueT transporter
GFGFMMDL_01505 6.43e-153 - - - L - - - Transposase DDE domain
GFGFMMDL_01506 1.83e-235 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
GFGFMMDL_01507 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GFGFMMDL_01508 5.63e-111 ccl - - S - - - cog cog4708
GFGFMMDL_01509 4.07e-206 rbn - - E ko:K07058 - ko00000 Belongs to the UPF0761 family
GFGFMMDL_01510 2.86e-211 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
GFGFMMDL_01511 4.31e-295 ytoI - - K - - - transcriptional regulator containing CBS domains
GFGFMMDL_01512 2.39e-126 XK27_07830 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase GNAT Family
GFGFMMDL_01513 7.78e-15 - - - L ko:K07485 - ko00000 Transposase
GFGFMMDL_01515 1.75e-294 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GFGFMMDL_01516 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
GFGFMMDL_01517 2.9e-138 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
GFGFMMDL_01518 2.06e-182 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
GFGFMMDL_01519 1.32e-195 nodB3 - - G - - - deacetylase
GFGFMMDL_01520 4.3e-177 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase
GFGFMMDL_01521 4.12e-56 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
GFGFMMDL_01522 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
GFGFMMDL_01523 5.4e-199 corA - - P - - - CorA-like protein
GFGFMMDL_01524 6.17e-82 yjqA - - S - - - Bacterial PH domain
GFGFMMDL_01525 7.58e-128 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter
GFGFMMDL_01526 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GFGFMMDL_01527 1.86e-137 ywaF - - S - - - Integral membrane protein (intg_mem_TP0381)
GFGFMMDL_01528 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
GFGFMMDL_01531 7.77e-199 cjaA - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
GFGFMMDL_01532 5.18e-172 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 abc transporter atp-binding protein
GFGFMMDL_01533 1.4e-148 glnP7 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter (Permease
GFGFMMDL_01534 4.76e-146 glnP9 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter (Permease
GFGFMMDL_01535 6.23e-244 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
GFGFMMDL_01536 1.91e-42 copZ - - P - - - Heavy metal-associated domain protein
GFGFMMDL_01537 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
GFGFMMDL_01538 4.81e-94 copY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor, CopY TcrY family
GFGFMMDL_01539 1.5e-184 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
GFGFMMDL_01540 1e-290 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
GFGFMMDL_01541 2.17e-128 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the TrpF family
GFGFMMDL_01542 7.62e-171 trpC 4.1.1.48 - E ko:K01609 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
GFGFMMDL_01543 2.69e-231 trpD 2.4.2.18, 4.1.3.27 - F ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GFGFMMDL_01544 2.03e-135 trpG 4.1.3.27 - EH ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 anthranilate
GFGFMMDL_01545 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GFGFMMDL_01546 9.49e-57 MA20_20425 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 - E ko:K00800,ko:K03785,ko:K04092,ko:K04782 ko00400,ko01053,ko01100,ko01110,ko01130,ko01230,map00400,map01053,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Chorismate mutase
GFGFMMDL_01547 2.94e-73 - - - - - - - -
GFGFMMDL_01548 0.0 ctpE - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
GFGFMMDL_01549 9.87e-33 - - - - - - - -
GFGFMMDL_01550 8.89e-88 - - - L ko:K07497 - ko00000 COG2801 Transposase and inactivated derivatives
GFGFMMDL_01551 5.88e-131 yiiE - - S - - - protein homotetramerization
GFGFMMDL_01553 4.25e-39 ytgB - - S - - - Membrane
GFGFMMDL_01554 3.07e-58 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GFGFMMDL_01555 8.53e-08 - - - L ko:K07497 - ko00000 transposition
GFGFMMDL_01556 1.67e-37 - - - L - - - transposase activity
GFGFMMDL_01557 4.94e-166 - - - K - - - transcriptional regulator, MerR family
GFGFMMDL_01558 4.56e-136 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
GFGFMMDL_01559 1.41e-80 WQ51_02910 - - S - - - Protein of unknown function, DUF536
GFGFMMDL_01560 1.05e-83 XK27_02560 - - S - - - cog cog2151
GFGFMMDL_01561 0.0 ilvD 4.2.1.9 - E ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the IlvD Edd family
GFGFMMDL_01562 9.59e-289 ytfP - - S ko:K07007 - ko00000 Flavoprotein
GFGFMMDL_01564 1.46e-154 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
GFGFMMDL_01565 4.89e-196 ytmP - - M - - - Phosphotransferase
GFGFMMDL_01566 3.5e-228 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
GFGFMMDL_01567 1.68e-168 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
GFGFMMDL_01568 1.02e-93 hit - - FG ko:K02503 - ko00000,ko04147 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
GFGFMMDL_01569 7.06e-14 - - - - - - - -
GFGFMMDL_01570 5.78e-69 - - - S - - - CD20-like family
GFGFMMDL_01571 7.72e-140 - - - - - - - -
GFGFMMDL_01572 0.0 clpL - - O ko:K04086 - ko00000,ko03110 ATP-dependent Clp protease ATP-binding subunit
GFGFMMDL_01573 5.22e-255 ylbM - - S - - - Belongs to the UPF0348 family
GFGFMMDL_01574 4.61e-178 XK27_06665 - - Q - - - Methyltransferase domain protein
GFGFMMDL_01575 9.81e-77 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
GFGFMMDL_01576 8.21e-139 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
GFGFMMDL_01577 3.58e-149 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GFGFMMDL_01578 1.59e-65 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
GFGFMMDL_01579 7.98e-275 yqeH - - S ko:K06948 - ko00000,ko03009 in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
GFGFMMDL_01580 1.84e-127 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
GFGFMMDL_01581 1.42e-195 - - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
GFGFMMDL_01582 4e-83 - - - - - - - -
GFGFMMDL_01583 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GFGFMMDL_01584 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
GFGFMMDL_01585 7.49e-64 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GFGFMMDL_01586 0.0 ascB 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
GFGFMMDL_01587 1.96e-125 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GFGFMMDL_01588 1.9e-196 metQ - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
GFGFMMDL_01589 3.02e-130 pncA - - Q ko:K16788 - ko00000,ko02000 isochorismatase
GFGFMMDL_01590 1.49e-180 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GFGFMMDL_01591 3.71e-303 aspC 2.6.1.2, 2.6.1.66 - E ko:K14260 ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
GFGFMMDL_01592 6.2e-98 XK27_03180 - - T - - - universal stress protein
GFGFMMDL_01593 1e-05 - - - L ko:K07483 - ko00000 transposase IS3 IS911 family protein
GFGFMMDL_01595 8.42e-194 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GFGFMMDL_01596 1.93e-302 hlyX - - S ko:K03699 - ko00000,ko02042 COG1253 Hemolysins and related proteins containing CBS domains
GFGFMMDL_01597 3.03e-184 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
GFGFMMDL_01598 0.0 nhaP1 - - P ko:K03316 - ko00000 NhaP-type Na H and K H antiporters
GFGFMMDL_01600 8.64e-125 mraW1 - - J - - - (SAM)-dependent
GFGFMMDL_01601 1.77e-235 ytqA - - S ko:K07139 - ko00000 radical SAM protein
GFGFMMDL_01602 2.45e-246 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
GFGFMMDL_01603 5.14e-111 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GFGFMMDL_01604 1.23e-118 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
GFGFMMDL_01605 2.09e-214 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
GFGFMMDL_01606 5.53e-11 - - - S - - - Protein of unknown function (DUF4059)
GFGFMMDL_01607 5.38e-167 tcyN 3.6.3.21 - E ko:K02028,ko:K10010,ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
GFGFMMDL_01608 9.44e-207 yxeN - - P ko:K02029,ko:K16959,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
GFGFMMDL_01609 1.66e-191 - - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC-type amino acid transport signal transduction systems, periplasmic component domain
GFGFMMDL_01611 2.9e-254 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GFGFMMDL_01612 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 formate acetyltransferase'
GFGFMMDL_01613 2.53e-51 - - - L ko:K07497 - ko00000 HTH-like domain
GFGFMMDL_01614 1.54e-124 - - - L ko:K07483 - ko00000 transposase IS3 IS911 family protein
GFGFMMDL_01615 6.92e-190 cah 4.2.1.1 - P ko:K01674 ko00910,map00910 ko00000,ko00001,ko01000 carbonic anhydrase
GFGFMMDL_01616 9.32e-112 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GFGFMMDL_01617 1.11e-67 hsdS_1 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain
GFGFMMDL_01618 3.7e-42 - - - D - - - nuclear chromosome segregation
GFGFMMDL_01619 9.95e-165 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
GFGFMMDL_01620 2.51e-152 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
GFGFMMDL_01621 4.14e-235 - - - V - - - COG1680 Beta-lactamase class C and other penicillin binding proteins
GFGFMMDL_01622 6.61e-179 cppA - - E - - - CppA N-terminal
GFGFMMDL_01623 2.69e-56 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
GFGFMMDL_01624 1.26e-210 gla - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
GFGFMMDL_01625 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
GFGFMMDL_01628 2.17e-62 spiA - - K ko:K18831 - ko00000,ko02048,ko03000 sequence-specific DNA binding
GFGFMMDL_01629 1.11e-210 blpT - - - - - - -
GFGFMMDL_01637 0.000313 - - - - - - - -
GFGFMMDL_01638 1.08e-34 - - - S - - - Bacteriocin class II with double-glycine leader peptide
GFGFMMDL_01641 1.28e-173 agrA - - KT ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 phosphorelay signal transduction system
GFGFMMDL_01642 3.17e-298 blpH 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
GFGFMMDL_01644 2.56e-230 mesE - - M ko:K20345 ko02024,map02024 ko00000,ko00001,ko02000 Transport protein ComB
GFGFMMDL_01645 8.84e-62 mesE - - M ko:K20345 ko02024,map02024 ko00000,ko00001,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GFGFMMDL_01646 0.0 comA - - V ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
GFGFMMDL_01647 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
GFGFMMDL_01648 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
GFGFMMDL_01650 2.82e-122 XK27_09885 - - V - - - Glycopeptide antibiotics resistance protein
GFGFMMDL_01651 3.73e-284 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
GFGFMMDL_01652 1.83e-134 yutD - - J - - - protein conserved in bacteria
GFGFMMDL_01653 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
GFGFMMDL_01655 1.12e-303 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
GFGFMMDL_01656 3.29e-235 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GFGFMMDL_01657 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 penicillin-binding protein
GFGFMMDL_01658 3.89e-62 ftsL - - D - - - cell division protein FtsL
GFGFMMDL_01659 1.54e-221 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
GFGFMMDL_01660 6.56e-84 - - - - - - - -
GFGFMMDL_01661 2.52e-34 - - - - - - - -
GFGFMMDL_01662 3.81e-55 - - - - - - - -
GFGFMMDL_01664 6.09e-40 - - - J - - - Protein of unknown function (DUF805)
GFGFMMDL_01665 3.98e-33 - - - D - - - nuclear chromosome segregation
GFGFMMDL_01666 7.05e-289 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GFGFMMDL_01667 3.23e-178 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GFGFMMDL_01668 0.0 XK27_00765 - - - ko:K01992 - ko00000,ko00002,ko02000 -
GFGFMMDL_01669 1.68e-168 ecsA_2 - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
GFGFMMDL_01670 6.75e-143 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
GFGFMMDL_01671 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
GFGFMMDL_01672 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
GFGFMMDL_01673 6.19e-70 - - - S - - - membrane
GFGFMMDL_01674 4.73e-14 XK27_02470 - - K - - - LytTr DNA-binding domain protein
GFGFMMDL_01675 5.19e-63 - - - KT - - - response to antibiotic
GFGFMMDL_01676 1.35e-13 - - - KT - - - response to antibiotic
GFGFMMDL_01677 6.48e-22 - - - KT - - - response to antibiotic
GFGFMMDL_01678 5.82e-118 yebC - - M - - - Membrane
GFGFMMDL_01679 4.09e-24 yebC - - M - - - Membrane
GFGFMMDL_01680 0.0 - - - S - - - hydrolases of the HAD superfamily
GFGFMMDL_01681 3.38e-215 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
GFGFMMDL_01682 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GFGFMMDL_01683 1.41e-245 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GFGFMMDL_01684 1.23e-80 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
GFGFMMDL_01685 4.1e-251 aroG 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GFGFMMDL_01686 2.03e-251 aroH 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GFGFMMDL_01687 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
GFGFMMDL_01689 1.03e-239 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
GFGFMMDL_01690 5.59e-219 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 Fructokinase
GFGFMMDL_01691 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
GFGFMMDL_01692 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
GFGFMMDL_01693 1.74e-225 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional
GFGFMMDL_01694 1.27e-94 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GFGFMMDL_01695 9.01e-81 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 protein conserved in bacteria
GFGFMMDL_01696 6.05e-127 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GFGFMMDL_01697 1.43e-109 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
GFGFMMDL_01698 2.05e-256 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Belongs to the peptidase M24B family
GFGFMMDL_01701 6.83e-76 - - - V ko:K01990,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 'abc transporter, ATP-binding protein
GFGFMMDL_01707 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GFGFMMDL_01708 8.18e-216 corA - - P ko:K03284 - ko00000,ko02000 COG0598 Mg2 and Co2 transporters
GFGFMMDL_01709 5.91e-159 - - - S - - - Pfam PF06570
GFGFMMDL_01711 2.03e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GFGFMMDL_01712 2.07e-118 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
GFGFMMDL_01713 3.11e-62 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
GFGFMMDL_01714 2.77e-50 XK27_05745 - - - - - - -
GFGFMMDL_01715 4.56e-291 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific adenine glycosylase
GFGFMMDL_01718 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GFGFMMDL_01719 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
GFGFMMDL_01720 3.39e-121 cvpA - - S ko:K03558 - ko00000 toxin biosynthetic process
GFGFMMDL_01721 5.78e-19 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GFGFMMDL_01722 4.7e-206 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GFGFMMDL_01723 2.62e-145 spi 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
GFGFMMDL_01724 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
GFGFMMDL_01725 1.91e-63 azlD - - E - - - branched-chain amino acid
GFGFMMDL_01726 7.55e-150 XK27_12120 - - E - - - AzlC protein
GFGFMMDL_01727 6.68e-238 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GFGFMMDL_01728 1.54e-96 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
GFGFMMDL_01729 2.39e-156 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214, inactive homolog of metal-dependent proteases
GFGFMMDL_01730 6.45e-45 ykzG - - S - - - Belongs to the UPF0356 family
GFGFMMDL_01731 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GFGFMMDL_01733 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
GFGFMMDL_01734 1.12e-83 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 Transcriptional regulator
GFGFMMDL_01735 1.08e-113 - - - S - - - Fusaric acid resistance protein-like
GFGFMMDL_01736 5.33e-16 - - - - - - - -
GFGFMMDL_01737 6.41e-281 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
GFGFMMDL_01738 8.75e-54 - - - L ko:K07491 - ko00000 COG1943 Transposase and inactivated derivatives
GFGFMMDL_01740 1.23e-237 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
GFGFMMDL_01741 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GFGFMMDL_01742 3.83e-104 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
GFGFMMDL_01743 3.31e-89 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GFGFMMDL_01744 1.09e-184 purR - - F ko:K09685 - ko00000,ko03000 operon repressor
GFGFMMDL_01745 4.81e-229 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 3'-5' exoribonuclease yhaM
GFGFMMDL_01746 1.33e-235 rmuC - - S ko:K09760 - ko00000 RmuC domain protein
GFGFMMDL_01747 2.73e-153 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
GFGFMMDL_01748 6.49e-152 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
GFGFMMDL_01749 2.26e-210 rsgA 3.1.3.100 - G ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
GFGFMMDL_01751 4.31e-199 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
GFGFMMDL_01752 7.36e-128 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GFGFMMDL_01753 1.5e-183 tatD - - L ko:K03424 - ko00000,ko01000 Hydrolase, tatd
GFGFMMDL_01754 1.9e-97 yneT - - S ko:K06929 - ko00000 CoA-binding protein
GFGFMMDL_01755 1.54e-67 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
GFGFMMDL_01756 5.24e-185 - - - S - - - Macro domain protein
GFGFMMDL_01758 2.38e-72 bta 1.8.1.8 - CO ko:K03671,ko:K03672 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko01000,ko03110 cell redox homeostasis
GFGFMMDL_01759 2.84e-288 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
GFGFMMDL_01760 1.9e-109 - - - L ko:K07491 - ko00000 Transposase
GFGFMMDL_01761 9.33e-20 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L34
GFGFMMDL_01762 1.14e-235 jag - - S ko:K06346 - ko00000 RNA-binding protein
GFGFMMDL_01763 1.8e-180 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GFGFMMDL_01764 1.38e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
GFGFMMDL_01765 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Argininosuccinate lyase
GFGFMMDL_01766 1.85e-293 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
GFGFMMDL_01767 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GFGFMMDL_01768 7.64e-111 amiA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
GFGFMMDL_01769 9.45e-228 amiA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
GFGFMMDL_01770 1.29e-33 amiA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
GFGFMMDL_01771 1.94e-155 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
GFGFMMDL_01772 1.69e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GFGFMMDL_01773 3.28e-66 - - - S - - - Protein of unknown function (DUF3397)
GFGFMMDL_01774 9.62e-116 cah 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
GFGFMMDL_01775 1.23e-40 WQ51_05710 - - S - - - Mitochondrial biogenesis AIM24
GFGFMMDL_01776 1.64e-16 - - - S - - - Mitochondrial biogenesis AIM24
GFGFMMDL_01777 1.26e-286 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GFGFMMDL_01778 2.98e-104 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
GFGFMMDL_01779 1.24e-26 XK27_09620 - - S - - - FMN reductase (NADPH) activity
GFGFMMDL_01780 6.36e-93 - - - S - - - reductase
GFGFMMDL_01781 3.56e-280 XK27_09615 - - C ko:K19784 - ko00000 reductase
GFGFMMDL_01782 4.07e-31 nirC_1 - - P - - - Formate nitrite transporter
GFGFMMDL_01783 8.23e-81 nirC_1 - - P - - - Formate nitrite transporter
GFGFMMDL_01784 1.98e-108 XK27_08585 - - S ko:K16926 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score
GFGFMMDL_01785 7.25e-237 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
GFGFMMDL_01786 4.4e-215 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
GFGFMMDL_01787 2.79e-153 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
GFGFMMDL_01788 9.45e-121 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GFGFMMDL_01789 3.29e-281 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
GFGFMMDL_01790 6.92e-105 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
GFGFMMDL_01791 7.38e-61 - - - S ko:K07025 - ko00000 glycolate biosynthetic process
GFGFMMDL_01792 5.33e-86 - - - S ko:K07025 - ko00000 phosphatase activity
GFGFMMDL_01793 8.48e-204 rrmA 2.1.1.187 - Q ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 methyltransferase
GFGFMMDL_01796 5.94e-118 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
GFGFMMDL_01797 3.13e-86 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
GFGFMMDL_01798 1.85e-48 yeeD - - O ko:K07112 - ko00000 sulfur carrier activity
GFGFMMDL_01799 1.79e-245 yeeE - - S ko:K07112 - ko00000 Sulphur transport
GFGFMMDL_01800 1.3e-145 XK27_10290 - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GFGFMMDL_01801 4.07e-72 ytpP - - CO - - - Thioredoxin
GFGFMMDL_01803 5.26e-260 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
GFGFMMDL_01804 4.76e-170 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GFGFMMDL_01805 3.93e-142 - - - S ko:K07052 - ko00000 CAAX amino terminal protease family protein
GFGFMMDL_01807 2.16e-84 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
GFGFMMDL_01808 6.81e-42 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
GFGFMMDL_01809 8.68e-36 lanR - - K ko:K07729 - ko00000,ko03000 sequence-specific DNA binding
GFGFMMDL_01810 8.04e-283 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GFGFMMDL_01811 2.04e-227 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
GFGFMMDL_01812 1.77e-08 - - - - - - - -
GFGFMMDL_01813 4.41e-91 comGF - - U ko:K02248 - ko00000,ko00002,ko02044 Competence protein ComGF
GFGFMMDL_01814 7.38e-21 - - - NU - - - Type II secretory pathway pseudopilin
GFGFMMDL_01815 2e-73 cglD - - NU ko:K02246 - ko00000,ko00002,ko02044 Competence protein
GFGFMMDL_01816 2.23e-62 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
GFGFMMDL_01817 3.32e-183 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
GFGFMMDL_01818 9.35e-226 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GFGFMMDL_01819 1.09e-88 - - - S - - - cog cog4699
GFGFMMDL_01820 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GFGFMMDL_01821 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GFGFMMDL_01822 0.0 pbp1B 2.4.1.129 GT51 M ko:K03693,ko:K12551 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
GFGFMMDL_01823 1.18e-302 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GFGFMMDL_01824 2.67e-250 ilvC 1.1.1.86 - H ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GFGFMMDL_01825 1.67e-99 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
GFGFMMDL_01826 0.0 ilvB 2.2.1.6 - EH ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
GFGFMMDL_01827 4.29e-75 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
GFGFMMDL_01828 1.22e-284 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
GFGFMMDL_01829 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
GFGFMMDL_01830 1.87e-76 asp - - S - - - cog cog1302
GFGFMMDL_01831 7.56e-286 norN - - V - - - Mate efflux family protein
GFGFMMDL_01832 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
GFGFMMDL_01833 4.82e-45 adh 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
GFGFMMDL_01834 7.27e-89 adh 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
GFGFMMDL_01835 1.7e-188 adh 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
GFGFMMDL_01836 9.57e-61 adh 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
GFGFMMDL_01837 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
GFGFMMDL_01838 1.85e-109 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
GFGFMMDL_01839 3.86e-98 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
GFGFMMDL_01840 4.07e-54 treP 2.7.1.201 - G ko:K02817,ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
GFGFMMDL_01841 3.49e-72 treB 2.7.1.201 - G ko:K02817,ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS System
GFGFMMDL_01842 2.66e-29 treR - - K ko:K03486,ko:K03710 - ko00000,ko03000 DNA-binding transcription factor activity
GFGFMMDL_01843 6.25e-112 treR - - K ko:K03486 - ko00000,ko03000 trehalose operon
GFGFMMDL_01844 2.27e-122 ywlG - - S - - - Belongs to the UPF0340 family
GFGFMMDL_01847 2.15e-156 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
GFGFMMDL_01848 1.53e-175 - - - HJ - - - the current gene model (or a revised gene model) may contain a frame shift
GFGFMMDL_01849 1.77e-261 - - - L - - - DNA integration
GFGFMMDL_01850 9.95e-211 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 aldolase
GFGFMMDL_01852 2.51e-133 - 6.3.2.2 - H ko:K01919,ko:K06048 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 ergothioneine biosynthetic process
GFGFMMDL_01853 1.44e-41 - - - H - - - gamma-glutamylcysteine synthetase
GFGFMMDL_01854 1.43e-15 - - - H - - - gamma-glutamylcysteine synthetase
GFGFMMDL_01855 6.19e-36 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
GFGFMMDL_01856 4.04e-87 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
GFGFMMDL_01857 2.13e-83 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 ribosomal protein l17
GFGFMMDL_01858 7.63e-220 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GFGFMMDL_01859 6.39e-80 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GFGFMMDL_01860 4.42e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GFGFMMDL_01861 3.26e-22 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
GFGFMMDL_01862 6.91e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GFGFMMDL_01863 2.61e-155 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
GFGFMMDL_01864 9.03e-295 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
GFGFMMDL_01865 3.45e-84 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
GFGFMMDL_01866 2e-32 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 ribosomal protein l30
GFGFMMDL_01867 4.05e-103 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GFGFMMDL_01868 5.03e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GFGFMMDL_01869 8.35e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GFGFMMDL_01870 5.37e-88 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GFGFMMDL_01871 1.18e-38 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GFGFMMDL_01872 5.86e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GFGFMMDL_01873 3.99e-64 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GFGFMMDL_01874 1.04e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GFGFMMDL_01875 3.08e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GFGFMMDL_01876 1.78e-34 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
GFGFMMDL_01877 2.07e-92 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GFGFMMDL_01878 6.38e-151 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GFGFMMDL_01879 1.21e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GFGFMMDL_01880 1.99e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GFGFMMDL_01881 1.69e-194 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GFGFMMDL_01882 6e-60 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
GFGFMMDL_01883 1.23e-134 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
GFGFMMDL_01884 1.83e-141 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GFGFMMDL_01885 2.39e-61 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
GFGFMMDL_01886 1.2e-238 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
GFGFMMDL_01887 0.0 XK27_09800 - - I - - - Acyltransferase
GFGFMMDL_01888 2.43e-47 - - - S - - - MORN repeat protein
GFGFMMDL_01889 1.32e-105 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GFGFMMDL_01891 7.73e-316 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GFGFMMDL_01892 4.25e-96 flaR - - F - - - topology modulation protein
GFGFMMDL_01893 3.04e-164 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GFGFMMDL_01894 2.93e-40 - - - S - - - Domain of unknown function (DUF4649)
GFGFMMDL_01896 2.16e-302 rarA - - L ko:K07478 - ko00000 ATPase related to the helicase subunit of the Holliday junction resolvase
GFGFMMDL_01897 1e-35 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
GFGFMMDL_01898 4.83e-59 yrzL - - S - - - Belongs to the UPF0297 family
GFGFMMDL_01899 8.4e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GFGFMMDL_01900 7.75e-62 yrzB - - S - - - Belongs to the UPF0473 family
GFGFMMDL_01901 0.0 - - - S - - - the current gene model (or a revised gene model) may contain a frame shift
GFGFMMDL_01902 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
GFGFMMDL_01903 7.68e-20 - - - - - - - -
GFGFMMDL_01904 1.31e-118 - - - K - - - acetyltransferase
GFGFMMDL_01905 7.3e-149 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GFGFMMDL_01906 1.39e-188 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
GFGFMMDL_01907 1.71e-212 XK27_01785 - - S - - - cog cog1284
GFGFMMDL_01908 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
GFGFMMDL_01910 1.94e-307 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
GFGFMMDL_01911 1.37e-170 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
GFGFMMDL_01912 2e-36 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
GFGFMMDL_01913 4.33e-36 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
GFGFMMDL_01914 1.22e-26 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
GFGFMMDL_01917 4.58e-145 yegS - - I - - - Diacylglycerol kinase
GFGFMMDL_01918 9.07e-20 yegS - - I - - - Diacylglycerol kinase
GFGFMMDL_01919 8.43e-124 - - - S - - - Hydrophobic domain protein
GFGFMMDL_01922 1.54e-39 ytgB - - S - - - Membrane
GFGFMMDL_01923 1.44e-104 - - - S - - - Asp23 family, cell envelope-related function
GFGFMMDL_01924 5.78e-35 - - - K - - - CsbD-like
GFGFMMDL_01925 1.96e-126 XK27_06885 - - L - - - hydrolase
GFGFMMDL_01926 2.9e-18 XK27_06885 - - L - - - hydrolase
GFGFMMDL_01927 2.32e-64 XK27_06915 - - K ko:K10947 - ko00000,ko03000 transcriptional regulator, PadR family
GFGFMMDL_01928 1.91e-10 - - - S - - - Protein of unknown function (DUF1700)
GFGFMMDL_01929 4.55e-40 XK27_06920 - - S - - - membrane
GFGFMMDL_01930 1.3e-138 - - - S - - - Putative adhesin
GFGFMMDL_01931 5.57e-246 XK27_06930 - - V ko:K01421 - ko00000 domain protein
GFGFMMDL_01932 2.69e-122 XK27_06935 - - K - - - transcriptional regulator
GFGFMMDL_01933 3.12e-70 ypaA - - S ko:K08987 - ko00000 membrane
GFGFMMDL_01934 8.41e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GFGFMMDL_01935 3.05e-63 WQ51_01655 - - S - - - Biofilm formation stimulator VEG
GFGFMMDL_01936 5.24e-312 dnaC 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
GFGFMMDL_01937 1.24e-98 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
GFGFMMDL_01938 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
GFGFMMDL_01939 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
GFGFMMDL_01940 1.78e-102 - - - F - - - NUDIX domain
GFGFMMDL_01941 1.28e-276 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
GFGFMMDL_01942 0.0 - - - S - - - Bacterial membrane protein, YfhO
GFGFMMDL_01943 3.54e-119 isaA - - M - - - Immunodominant staphylococcal antigen A
GFGFMMDL_01944 4.06e-115 lytE - - M - - - LysM domain protein
GFGFMMDL_01945 9.99e-176 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GFGFMMDL_01946 1.5e-194 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GFGFMMDL_01947 7.44e-193 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GFGFMMDL_01948 2.2e-117 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GFGFMMDL_01949 1.2e-182 ymfM - - S ko:K15539 - ko00000 sequence-specific DNA binding
GFGFMMDL_01950 1.26e-305 ymfH - - S - - - Peptidase M16
GFGFMMDL_01951 1.97e-295 albE - - S - - - Peptidase M16
GFGFMMDL_01952 3.04e-68 yaaA - - S - - - S4 domain protein YaaA
GFGFMMDL_01953 3.72e-261 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GFGFMMDL_01954 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
GFGFMMDL_01955 1.17e-244 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
GFGFMMDL_01956 5.63e-195 XK27_10395 - - S - - - membrane
GFGFMMDL_01957 0.0 ykpA - - S - - - abc transporter atp-binding protein
GFGFMMDL_01958 0.0 XK27_10405 - - S - - - Bacterial membrane protein YfhO
GFGFMMDL_01962 4.81e-93 yoaK - - S - - - Protein of unknown function (DUF1275)
GFGFMMDL_01963 3.39e-45 yoaK - - S - - - Protein of unknown function (DUF1275)
GFGFMMDL_01964 1.72e-109 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GFGFMMDL_01965 1.85e-254 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
GFGFMMDL_01966 2.18e-170 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
GFGFMMDL_01967 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GFGFMMDL_01968 1.75e-256 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
GFGFMMDL_01969 8.11e-40 yyzM - - S - - - Protein conserved in bacteria
GFGFMMDL_01970 1.06e-258 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
GFGFMMDL_01971 4.43e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
GFGFMMDL_01972 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GFGFMMDL_01973 3.77e-53 yabO - - J - - - Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
GFGFMMDL_01974 1.16e-80 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
GFGFMMDL_01975 8.8e-06 - - - - - - - -
GFGFMMDL_01976 3.62e-305 - 3.5.2.6 - V ko:K01467 ko01501,ko02020,map01501,map02020 ko00000,ko00001,ko00002,ko01000 Beta-lactamase enzyme family
GFGFMMDL_01977 5.13e-305 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
GFGFMMDL_01978 2.22e-126 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
GFGFMMDL_01979 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GFGFMMDL_01981 3.47e-215 - - - L - - - Replication protein
GFGFMMDL_01982 1.01e-90 hsp1 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
GFGFMMDL_01984 1.53e-07 - - - L ko:K07483 - ko00000 transposase IS3 IS911 family protein
GFGFMMDL_01985 1.31e-97 tspO - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 TspO/MBR family
GFGFMMDL_01986 2.17e-76 - - - S - - - Uncharacterised lipoprotein family
GFGFMMDL_01987 4.58e-156 - - - L - - - Transposase
GFGFMMDL_01988 2.94e-207 - - - L ko:K07497 - ko00000 integrase core domain
GFGFMMDL_01989 9.92e-18 B4168_4126 - - L ko:K07493 - ko00000 Transposase
GFGFMMDL_01990 2.1e-114 - - - K - - - Acetyltransferase GNAT Family
GFGFMMDL_01991 1.44e-92 - 3.2.2.10 - L ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
GFGFMMDL_01992 4.6e-147 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type proline glycine betaine transport systems permease component
GFGFMMDL_01993 7.81e-149 proWX - - P ko:K05845,ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type proline glycine betaine transport systems, permease component
GFGFMMDL_01994 3.39e-137 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GFGFMMDL_01995 1.83e-278 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
GFGFMMDL_01996 1.1e-60 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
GFGFMMDL_01997 1.97e-78 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
GFGFMMDL_01999 3.75e-18 - - - - - - - -
GFGFMMDL_02000 3.1e-75 - - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)