ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
GDMGHCMF_00018 6.73e-180 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
GDMGHCMF_00019 6.37e-114 mreD - - M ko:K03571 - ko00000,ko03036 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GDMGHCMF_00020 7.64e-182 pcsB - - S ko:K21471 - ko00000,ko01000,ko01002,ko01011 CHAP domain
GDMGHCMF_00021 4.76e-224 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GDMGHCMF_00022 1.07e-35 - - - - - - - -
GDMGHCMF_00023 2.59e-279 araT - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
GDMGHCMF_00024 2.81e-183 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
GDMGHCMF_00025 7.72e-231 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
GDMGHCMF_00026 1.93e-46 acpP_1 - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
GDMGHCMF_00027 1.01e-165 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
GDMGHCMF_00028 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GDMGHCMF_00029 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GDMGHCMF_00030 4.91e-241 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
GDMGHCMF_00031 2.29e-130 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GDMGHCMF_00032 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
GDMGHCMF_00033 1.29e-112 - - - L ko:K07483 - ko00000 transposase activity
GDMGHCMF_00034 2.08e-66 - - - L ko:K07497 - ko00000 transposition
GDMGHCMF_00035 2.32e-43 - - - L ko:K07497 - ko00000 Integrase core domain protein
GDMGHCMF_00036 4.38e-207 - - - S - - - CHAP domain
GDMGHCMF_00037 1.65e-305 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
GDMGHCMF_00038 2.66e-99 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GDMGHCMF_00039 4e-259 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GDMGHCMF_00040 6.43e-111 - 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Ketopantoate reductase
GDMGHCMF_00041 4.75e-44 - - - - - - - -
GDMGHCMF_00042 1.98e-187 - - - J - - - Domain of unknown function (DUF4041)
GDMGHCMF_00044 1.75e-313 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GDMGHCMF_00045 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
GDMGHCMF_00046 2.08e-182 - - - L - - - Belongs to the 'phage' integrase family
GDMGHCMF_00047 2.97e-72 - - - L - - - Belongs to the 'phage' integrase family
GDMGHCMF_00048 2.24e-59 - - - K - - - Transcriptional
GDMGHCMF_00049 2.21e-27 - - - K - - - TRANSCRIPTIONal
GDMGHCMF_00054 4.49e-15 - - - - - - - -
GDMGHCMF_00055 7.5e-182 - - - KL ko:K06919 - ko00000 Phage plasmid primase P4 family
GDMGHCMF_00056 0.0 - - - S ko:K06919 - ko00000 DNA primase
GDMGHCMF_00060 4.53e-190 - - - V - - - Abi-like protein
GDMGHCMF_00062 1.36e-90 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
GDMGHCMF_00063 5.42e-75 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
GDMGHCMF_00064 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GDMGHCMF_00065 2.52e-102 - - - S - - - Protein of unknown function (DUF3021)
GDMGHCMF_00066 2.55e-90 - - - K - - - LytTr DNA-binding domain
GDMGHCMF_00068 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GDMGHCMF_00070 1.78e-133 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
GDMGHCMF_00071 3.67e-136 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 3-methyladenine DNA glycosylase
GDMGHCMF_00072 3.81e-292 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
GDMGHCMF_00073 8.4e-260 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GDMGHCMF_00074 2.46e-84 spxA_2 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
GDMGHCMF_00081 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GDMGHCMF_00082 1.63e-297 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
GDMGHCMF_00083 4.88e-49 XK27_02060 - - S - - - Transglycosylase associated protein
GDMGHCMF_00084 5.62e-88 - - - K - - - Transcriptional regulator, marr family
GDMGHCMF_00085 4.78e-122 XK27_03570 - - S ko:K19784 - ko00000 reductase
GDMGHCMF_00086 1.94e-191 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
GDMGHCMF_00087 4.18e-12 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
GDMGHCMF_00089 1.18e-174 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
GDMGHCMF_00090 3.35e-230 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GDMGHCMF_00091 6.89e-107 - - - S - - - Putative small multi-drug export protein
GDMGHCMF_00092 4.74e-97 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
GDMGHCMF_00093 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
GDMGHCMF_00094 7.19e-281 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
GDMGHCMF_00095 1.93e-286 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
GDMGHCMF_00096 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
GDMGHCMF_00097 1.83e-183 - - - S - - - SseB protein N-terminal domain
GDMGHCMF_00098 7.75e-145 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 serine acetyltransferase
GDMGHCMF_00099 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
GDMGHCMF_00100 2.02e-88 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GDMGHCMF_00103 4.11e-171 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GDMGHCMF_00104 6.97e-121 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
GDMGHCMF_00105 2.23e-199 yitS - - S - - - DegV family
GDMGHCMF_00106 1.67e-37 - - - K - - - helix-turn-helix
GDMGHCMF_00107 3.84e-232 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GDMGHCMF_00108 7.02e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GDMGHCMF_00109 3.52e-83 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
GDMGHCMF_00110 7.83e-188 - - - L - - - Phage integrase, N-terminal SAM-like domain
GDMGHCMF_00111 5.51e-47 - - - S - - - Helix-turn-helix domain
GDMGHCMF_00112 4.71e-178 - - - S - - - Psort location Cytoplasmic, score 8.87
GDMGHCMF_00113 1.1e-73 - - - - - - - -
GDMGHCMF_00114 4.5e-63 - - - - - - - -
GDMGHCMF_00115 3.07e-157 - - - - - - - -
GDMGHCMF_00116 7.48e-118 - - - K - - - Response regulator receiver domain protein
GDMGHCMF_00117 1.41e-134 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
GDMGHCMF_00118 3.78e-155 - - - V ko:K01990,ko:K19309 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GDMGHCMF_00119 1.71e-88 - - - S ko:K01992,ko:K19310 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
GDMGHCMF_00120 4.74e-286 int - - L - - - Belongs to the 'phage' integrase family
GDMGHCMF_00121 1.67e-51 - - - S - - - Helix-turn-helix domain
GDMGHCMF_00123 9.68e-220 - - - - - - - -
GDMGHCMF_00125 4.04e-95 isp2 - - S ko:K21471 - ko00000,ko01000,ko01002,ko01011 pathogenesis
GDMGHCMF_00126 2.66e-117 - - - L ko:K07498 - ko00000 Transposase
GDMGHCMF_00127 6.45e-284 capA - - M ko:K07282 - ko00000 Bacterial capsule synthesis protein
GDMGHCMF_00128 3.56e-52 XK27_08630 - - T ko:K07166 - ko00000 UPF0237 protein
GDMGHCMF_00129 2.28e-307 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
GDMGHCMF_00130 7.12e-165 gpmB - - G ko:K15640 - ko00000 Phosphoglycerate mutase
GDMGHCMF_00131 4.58e-177 yodJ 3.4.16.4, 3.4.17.14 - M ko:K01286,ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
GDMGHCMF_00132 3.46e-130 acmA 3.2.1.17 - NU ko:K01185,ko:K02395 - ko00000,ko01000,ko02035 amidase activity
GDMGHCMF_00133 2.19e-250 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
GDMGHCMF_00134 1.57e-96 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GDMGHCMF_00135 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
GDMGHCMF_00136 4.15e-253 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
GDMGHCMF_00137 1.02e-176 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
GDMGHCMF_00138 7.41e-177 thiD 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 phosphomethylpyrimidine kinase
GDMGHCMF_00139 3.37e-96 hmpT - - S - - - cog cog4720
GDMGHCMF_00140 7.24e-102 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 DNA-templated transcription, initiation
GDMGHCMF_00141 7.65e-188 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
GDMGHCMF_00142 5.08e-283 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
GDMGHCMF_00143 1.69e-115 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
GDMGHCMF_00144 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
GDMGHCMF_00145 3.99e-106 XK27_03960 - - S - - - Protein of unknown function (DUF3013)
GDMGHCMF_00146 1.17e-101 - 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
GDMGHCMF_00147 5.57e-220 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
GDMGHCMF_00148 1.68e-170 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
GDMGHCMF_00149 1.46e-49 cpdB 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
GDMGHCMF_00150 0.0 cpdB 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
GDMGHCMF_00151 6.19e-108 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
GDMGHCMF_00152 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GDMGHCMF_00153 1.94e-95 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
GDMGHCMF_00154 9.1e-33 dex 3.2.1.11 GH66 G ko:K05988 ko00500,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolase family 66
GDMGHCMF_00155 6.54e-44 dex 3.2.1.11 GH66 G ko:K05988 ko00500,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolase family 66
GDMGHCMF_00156 1.08e-30 dex 3.2.1.11 GH66 G ko:K05988 ko00500,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolase family 66
GDMGHCMF_00157 9.12e-301 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GDMGHCMF_00158 1.41e-143 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
GDMGHCMF_00159 2.13e-142 - - - K - - - Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
GDMGHCMF_00160 1.67e-254 XK27_00055 - - P - - - Major Facilitator
GDMGHCMF_00161 1.74e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GDMGHCMF_00162 6.67e-123 - - - V - - - VanZ like family
GDMGHCMF_00163 1.12e-14 - - - D - - - nuclear chromosome segregation
GDMGHCMF_00164 1.58e-180 - - - D - - - nuclear chromosome segregation
GDMGHCMF_00165 1.33e-51 - - - D - - - nuclear chromosome segregation
GDMGHCMF_00166 1.74e-167 glnQ - - E ko:K17076 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
GDMGHCMF_00167 0.0 XK27_05795 - - P ko:K17073,ko:K17074 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GDMGHCMF_00168 1.24e-195 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
GDMGHCMF_00169 5.6e-170 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
GDMGHCMF_00170 4.87e-246 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
GDMGHCMF_00171 5.2e-184 sufC - - O ko:K09013 - ko00000,ko02000 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
GDMGHCMF_00172 5.68e-297 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
GDMGHCMF_00173 7.76e-299 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GDMGHCMF_00174 1.09e-95 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
GDMGHCMF_00175 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
GDMGHCMF_00176 6.04e-13 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
GDMGHCMF_00177 1.42e-46 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
GDMGHCMF_00178 3.66e-196 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
GDMGHCMF_00179 1.19e-203 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GDMGHCMF_00180 2.21e-15 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GDMGHCMF_00181 9.56e-196 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GDMGHCMF_00182 2e-241 oppD - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GDMGHCMF_00183 1.11e-212 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GDMGHCMF_00184 3.08e-09 - - - - - - - -
GDMGHCMF_00185 3.85e-201 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GDMGHCMF_00186 2.41e-234 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GDMGHCMF_00187 1.03e-284 - - - EGP - - - Major facilitator Superfamily
GDMGHCMF_00188 1.28e-94 adcR - - K - - - transcriptional
GDMGHCMF_00189 5.07e-175 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GDMGHCMF_00190 4.95e-163 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
GDMGHCMF_00191 4.85e-207 mleP2 - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
GDMGHCMF_00192 0.0 ptsG 2.7.1.208 - G ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
GDMGHCMF_00193 5.9e-192 rgfB 3.1.3.90 - L ko:K06896 ko00500,map00500 ko00000,ko00001,ko01000 Endonuclease/Exonuclease/phosphatase family
GDMGHCMF_00194 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
GDMGHCMF_00195 1.26e-159 yeeN - - K - - - transcriptional regulatory protein
GDMGHCMF_00196 1.87e-65 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 protein transport
GDMGHCMF_00197 5.9e-181 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GDMGHCMF_00198 1.75e-185 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
GDMGHCMF_00199 2.12e-292 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
GDMGHCMF_00200 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
GDMGHCMF_00201 0.0 XK27_00665 - - S ko:K01989,ko:K05832 - ko00000,ko00002,ko02000 ABC transporter substrate binding protein
GDMGHCMF_00202 1.17e-180 cmpC - - S ko:K05833 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
GDMGHCMF_00203 2.91e-53 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GDMGHCMF_00204 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
GDMGHCMF_00205 2e-105 - - - L ko:K07485 - ko00000 Transposase
GDMGHCMF_00206 2.6e-132 - - - L - - - Transposase
GDMGHCMF_00207 3.91e-33 - - - K - - - Transcriptional regulator
GDMGHCMF_00208 2.6e-14 - - - - - - - -
GDMGHCMF_00210 4.62e-75 - - - S - - - very-long-chain-acyl-CoA dehydrogenase activity
GDMGHCMF_00211 5.35e-90 - - - - - - - -
GDMGHCMF_00213 9.99e-89 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
GDMGHCMF_00215 3.11e-171 drrA - - V ko:K01990,ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GDMGHCMF_00216 1.02e-136 - - - CP - - - ABC-2 family transporter protein
GDMGHCMF_00217 3.54e-169 - 1.6.5.5 - C ko:K00344 - ko00000,ko01000 NADPH:quinone reductase activity
GDMGHCMF_00218 4.21e-25 - - - L - - - Transposase
GDMGHCMF_00219 2.74e-34 - - - - - - - -
GDMGHCMF_00221 6.33e-72 WQ51_06355 - - S - - - TM2 domain
GDMGHCMF_00222 3.08e-208 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
GDMGHCMF_00223 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
GDMGHCMF_00224 4.01e-30 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
GDMGHCMF_00225 2.56e-34 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Belongs to the SecE SEC61-gamma family
GDMGHCMF_00226 1.62e-123 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
GDMGHCMF_00227 1.32e-107 - 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 - I ko:K01096,ko:K19302 ko00550,ko00564,ko01100,map00550,map00564,map01100 ko00000,ko00001,ko01000,ko01011 phosphatidate phosphatase activity
GDMGHCMF_00228 3.23e-58 cof - - Q - - - phosphatase activity
GDMGHCMF_00229 2.05e-42 cof - - Q - - - phosphatase activity
GDMGHCMF_00230 5.7e-110 - - - K ko:K22103 - ko00000,ko03000 transcriptional regulator (DeoR family)
GDMGHCMF_00231 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
GDMGHCMF_00232 1.31e-05 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
GDMGHCMF_00233 1.99e-251 - - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
GDMGHCMF_00234 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GDMGHCMF_00235 2.92e-193 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
GDMGHCMF_00236 1.69e-20 yhaI - - L - - - Membrane
GDMGHCMF_00237 5.1e-69 yhaI - - L - - - Membrane
GDMGHCMF_00238 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
GDMGHCMF_00239 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
GDMGHCMF_00240 9.56e-139 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
GDMGHCMF_00241 6.97e-121 ypsA - - S - - - Belongs to the UPF0398 family
GDMGHCMF_00242 4.13e-68 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
GDMGHCMF_00243 1.71e-284 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
GDMGHCMF_00244 0.0 mapZ - - D ko:K20073 - ko00000 Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
GDMGHCMF_00245 0.0 snf - - L - - - Superfamily II DNA RNA helicases, SNF2 family'
GDMGHCMF_00246 1.1e-25 XK27_11680 - - - - - - -
GDMGHCMF_00247 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
GDMGHCMF_00248 1.28e-65 XK27_09675 - - K ko:K07105 - ko00000 -acetyltransferase
GDMGHCMF_00249 0.0 mltG - - ADL ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GDMGHCMF_00250 6.78e-100 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GDMGHCMF_00251 4.1e-45 - - - L ko:K07497 - ko00000 Transposase and inactivated derivatives
GDMGHCMF_00252 2.42e-208 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GDMGHCMF_00253 3.84e-41 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
GDMGHCMF_00254 4.81e-169 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GDMGHCMF_00255 1.86e-114 XK27_09705 - - S ko:K06950 - ko00000 HD superfamily hydrolase
GDMGHCMF_00256 2e-144 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
GDMGHCMF_00259 9.18e-307 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
GDMGHCMF_00260 7.97e-115 - - - K - - - transcriptional regulator
GDMGHCMF_00261 5.74e-48 - - - S ko:K09976 - ko00000 UPF0154 protein
GDMGHCMF_00262 4.46e-187 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
GDMGHCMF_00263 1.64e-236 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GDMGHCMF_00264 1.3e-126 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
GDMGHCMF_00265 2.48e-111 ykuL - - S - - - CBS domain
GDMGHCMF_00266 4.14e-175 xerD - - L - - - tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
GDMGHCMF_00267 2.75e-155 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GDMGHCMF_00268 7.56e-129 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GDMGHCMF_00269 3.14e-179 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
GDMGHCMF_00270 1.05e-53 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
GDMGHCMF_00271 0.0 trkH - - P ko:K03498 - ko00000,ko02000 Cation transport protein
GDMGHCMF_00272 4.47e-311 trkA - - P ko:K03499 - ko00000,ko02000 Potassium transporter peripheral membrane component
GDMGHCMF_00273 1.34e-125 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
GDMGHCMF_00274 4.83e-118 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GDMGHCMF_00275 1.28e-145 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Membrane-associated phospholipid phosphatase
GDMGHCMF_00276 3.58e-207 - - - K ko:K20342,ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 sequence-specific DNA binding
GDMGHCMF_00277 3.36e-46 - - - V ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 protein secretion by the type I secretion system
GDMGHCMF_00278 2.45e-141 comA - - V ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
GDMGHCMF_00279 1.3e-91 comA - - V ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
GDMGHCMF_00280 1.55e-104 comA - - V ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
GDMGHCMF_00281 4.56e-61 yhaI - - L - - - Membrane
GDMGHCMF_00282 4.37e-124 ureI - - S ko:K03191 ko05120,map05120 ko00000,ko00001,ko02000 AmiS/UreI family transporter
GDMGHCMF_00283 1.02e-61 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
GDMGHCMF_00284 3.78e-72 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
GDMGHCMF_00285 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
GDMGHCMF_00286 1.58e-100 ureE - - O ko:K03187 - ko00000 enzyme active site formation
GDMGHCMF_00287 1.83e-169 ureF - - O ko:K03188 - ko00000 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
GDMGHCMF_00288 4.71e-142 ureG - - KO ko:K03189 - ko00000 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GDMGHCMF_00289 8.49e-205 ureD - - O ko:K03190 - ko00000 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
GDMGHCMF_00290 7.11e-227 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PDGLE domain
GDMGHCMF_00291 8.28e-177 nikQ - - P ko:K02008 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport protein
GDMGHCMF_00292 5.02e-167 - - - P ko:K02006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GDMGHCMF_00293 4.15e-177 - - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
GDMGHCMF_00294 2.14e-202 metQ - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
GDMGHCMF_00295 0.0 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
GDMGHCMF_00296 6.64e-238 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GDMGHCMF_00297 1.93e-147 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
GDMGHCMF_00298 8.48e-267 sstT - - E ko:K07862 - ko00000,ko02000 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
GDMGHCMF_00299 5e-106 ilvH - - S - - - S-adenosyl-l-methionine hydroxide adenosyltransferase
GDMGHCMF_00300 1.99e-75 ilvH - - S - - - S-adenosyl-l-methionine hydroxide adenosyltransferase
GDMGHCMF_00301 9.62e-55 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
GDMGHCMF_00302 5.27e-127 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
GDMGHCMF_00303 2.2e-235 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
GDMGHCMF_00304 1.18e-189 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
GDMGHCMF_00305 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GDMGHCMF_00306 1.05e-152 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
GDMGHCMF_00307 1.73e-306 ktrB - - P ko:K03498 - ko00000,ko02000 COG0168 Trk-type K transport systems, membrane components
GDMGHCMF_00308 1.18e-165 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Ribosomal RNA small subunit methyltransferase G
GDMGHCMF_00309 2.21e-116 ylbN - - K ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
GDMGHCMF_00310 1.28e-156 csrR - - T - - - Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GDMGHCMF_00311 0.0 covS - - T - - - Histidine kinase
GDMGHCMF_00312 2.42e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GDMGHCMF_00313 2.28e-270 dnaB - - L ko:K03346 - ko00000,ko03032 Replication initiation and membrane attachment
GDMGHCMF_00314 8.49e-211 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
GDMGHCMF_00315 5.64e-312 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
GDMGHCMF_00316 1.45e-35 - - - - - - - -
GDMGHCMF_00317 1.25e-294 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GDMGHCMF_00318 1.85e-82 manO - - S - - - protein conserved in bacteria
GDMGHCMF_00319 4.74e-212 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose fructose sorbose family IID component
GDMGHCMF_00320 1.09e-156 manM - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 pts system
GDMGHCMF_00321 2.17e-219 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
GDMGHCMF_00322 1.84e-181 XK27_00940 3.5.1.9 - S ko:K07130 ko00380,ko00630,ko01100,map00380,map00630,map01100 ko00000,ko00001,ko00002,ko01000 Metal-dependent hydrolase
GDMGHCMF_00323 2.42e-195 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
GDMGHCMF_00324 6.23e-305 XK27_07275 - - S ko:K06901 - ko00000,ko02000 permease
GDMGHCMF_00325 1.54e-26 B4168_4126 - - L ko:K07493 - ko00000 Transposase
GDMGHCMF_00326 1.54e-101 ydiB - - M ko:K06925 - ko00000,ko03016 ATPase or kinase
GDMGHCMF_00327 3.05e-116 - - - M - - - Acetyltransferase GNAT Family
GDMGHCMF_00328 1.1e-263 brpA - - K - - - Transcriptional
GDMGHCMF_00329 7.22e-104 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
GDMGHCMF_00330 4.11e-270 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
GDMGHCMF_00331 1.58e-62 ylxR - - K ko:K07742 - ko00000 Nucleic-acid-binding protein implicated in transcription termination
GDMGHCMF_00332 2.19e-56 ylxQ - - J - - - ribosomal protein
GDMGHCMF_00333 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GDMGHCMF_00334 8.07e-76 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GDMGHCMF_00335 1.09e-69 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
GDMGHCMF_00336 4.14e-281 femA 2.3.2.17 - V ko:K11694 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01011 protein involved in methicillin resistance
GDMGHCMF_00337 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GDMGHCMF_00338 0.0 ytgP - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
GDMGHCMF_00339 9.98e-61 pacL - - P - - - cation transport ATPase
GDMGHCMF_00340 1.27e-48 pacL - - P - - - cation transport ATPase
GDMGHCMF_00341 6.87e-256 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
GDMGHCMF_00342 1.42e-279 malY 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
GDMGHCMF_00344 6.16e-145 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GDMGHCMF_00345 7.57e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
GDMGHCMF_00346 1.3e-94 ylbF - - S - - - Belongs to the UPF0342 family
GDMGHCMF_00347 4.33e-62 ylbG - - S - - - UPF0298 protein
GDMGHCMF_00348 2.18e-268 livJ - - E ko:K01999 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
GDMGHCMF_00349 3.33e-189 livH - - E ko:K01997 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
GDMGHCMF_00350 7.76e-183 livM - - E ko:K01998 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
GDMGHCMF_00351 3.96e-177 livG - - E ko:K01995 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
GDMGHCMF_00352 5.36e-157 livF - - E ko:K01996 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
GDMGHCMF_00353 9.43e-90 acuB - - S ko:K04767 - ko00000 IMP dehydrogenase activity
GDMGHCMF_00354 5.12e-56 acuB - - S ko:K04767 - ko00000 IMP dehydrogenase activity
GDMGHCMF_00355 1.25e-212 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
GDMGHCMF_00356 3.86e-143 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
GDMGHCMF_00357 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GDMGHCMF_00358 8.03e-156 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
GDMGHCMF_00359 7.65e-119 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GDMGHCMF_00363 2.85e-214 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
GDMGHCMF_00364 7.47e-151 - - - S - - - Domain of unknown function (DUF1803)
GDMGHCMF_00365 9.83e-133 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
GDMGHCMF_00366 2.56e-175 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
GDMGHCMF_00367 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GDMGHCMF_00368 5.12e-243 asnA 6.3.1.1 - E ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
GDMGHCMF_00369 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
GDMGHCMF_00370 2.94e-149 - - - S - - - Haloacid dehalogenase-like hydrolase
GDMGHCMF_00371 1.67e-178 phaB 5.3.3.14, 5.3.3.18 - I ko:K15866,ko:K18474 ko00061,ko00360,ko01120,map00061,map00360,map01120 ko00000,ko00001,ko01000,ko01004 Belongs to the enoyl-CoA hydratase isomerase family
GDMGHCMF_00372 4.43e-95 XK27_02735 - - K - - - Transcriptional regulator, MarR family
GDMGHCMF_00373 1.88e-224 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GDMGHCMF_00374 6.09e-40 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
GDMGHCMF_00375 1.03e-217 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 2-Nitropropane dioxygenase
GDMGHCMF_00376 8.74e-207 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
GDMGHCMF_00377 2.76e-163 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
GDMGHCMF_00378 4.12e-294 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
GDMGHCMF_00379 5.36e-84 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
GDMGHCMF_00380 3.98e-92 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
GDMGHCMF_00381 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
GDMGHCMF_00382 1.71e-204 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GDMGHCMF_00383 2.68e-176 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
GDMGHCMF_00384 5.41e-115 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
GDMGHCMF_00385 2.37e-50 - - - L ko:K07498 - ko00000 Transposase
GDMGHCMF_00386 2.43e-78 - - - S - - - Bacterial PH domain
GDMGHCMF_00390 1.57e-37 - - - S - - - Antidote-toxin recognition MazE, bacterial antitoxin
GDMGHCMF_00391 1.54e-128 - - - L ko:K07497 - ko00000 COG2801 Transposase and inactivated derivatives
GDMGHCMF_00392 5.56e-124 - - - - - - - -
GDMGHCMF_00393 9.57e-117 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
GDMGHCMF_00394 0.0 - - - L - - - Recombinase zinc beta ribbon domain
GDMGHCMF_00395 5.6e-45 xre - - K - - - transcriptional
GDMGHCMF_00396 1.01e-178 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
GDMGHCMF_00397 3.69e-153 - - - P - - - ABC-2 family transporter protein
GDMGHCMF_00398 7.6e-200 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
GDMGHCMF_00399 0.0 - - - Q - - - Beta-ketoacyl synthase
GDMGHCMF_00400 8.26e-205 - - - I - - - malonyl CoA-acyl carrier protein transacylase
GDMGHCMF_00401 0.0 - - - H ko:K04784,ko:K12240 ko01053,map01053 ko00000,ko00001,ko01004,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GDMGHCMF_00402 5.12e-07 - - - L ko:K07483 - ko00000 transposase activity
GDMGHCMF_00403 1.04e-309 rny - - D ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
GDMGHCMF_00404 1.46e-54 - - - S - - - Domain of unknown function (DUF1803)
GDMGHCMF_00405 1.16e-60 - - - S - - - Domain of unknown function (DUF1803)
GDMGHCMF_00406 1.43e-198 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GDMGHCMF_00407 4.02e-220 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GDMGHCMF_00408 2.06e-207 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
GDMGHCMF_00409 1.17e-172 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
GDMGHCMF_00410 5.15e-19 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GDMGHCMF_00411 1.8e-122 gshF 6.3.2.2 - H ko:K01919,ko:K16786,ko:K16787 ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the glutamate--cysteine ligase type 1 family
GDMGHCMF_00412 1.9e-74 - - - - - - - -
GDMGHCMF_00413 8.24e-274 XK27_12990 - - P - - - Belongs to the TelA family
GDMGHCMF_00414 1.03e-50 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GDMGHCMF_00415 3.78e-142 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GDMGHCMF_00416 1.37e-165 fruR - - K ko:K03436 - ko00000,ko03000 transcriptional
GDMGHCMF_00417 4.18e-208 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
GDMGHCMF_00418 0.0 fruA 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GDMGHCMF_00419 0.0 gor 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GDMGHCMF_00420 1.99e-304 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
GDMGHCMF_00421 1.8e-06 - - - - - - - -
GDMGHCMF_00422 1e-268 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
GDMGHCMF_00423 5.54e-286 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GDMGHCMF_00424 0.0 gtf1 - - M - - - An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
GDMGHCMF_00425 0.0 gtf2 - - M - - - A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
GDMGHCMF_00426 6.44e-50 - 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 acetyltransferase
GDMGHCMF_00427 4.27e-35 - 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 acetyltransferase
GDMGHCMF_00428 1.99e-64 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
GDMGHCMF_00429 1.55e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
GDMGHCMF_00430 5.52e-171 - - - L ko:K07485 - ko00000 Transposase
GDMGHCMF_00431 7.6e-101 - - - L ko:K07485 - ko00000 Transposase
GDMGHCMF_00432 4.68e-27 ydaF_2 - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GDMGHCMF_00433 2.21e-64 ydaF_2 - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GDMGHCMF_00434 2.74e-84 WQ51_03320 - - S - - - cog cog4835
GDMGHCMF_00435 8.55e-185 - - - S - - - EDD domain protein, DegV family
GDMGHCMF_00436 2.48e-176 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
GDMGHCMF_00437 1.08e-285 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GDMGHCMF_00438 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 abc transporter atp-binding protein
GDMGHCMF_00439 5.61e-28 - - - S - - - Short repeat of unknown function (DUF308)
GDMGHCMF_00440 5.45e-176 - - - F - - - AdP-ribose pyrophosphatase
GDMGHCMF_00441 1.9e-229 nadR - - H - - - adenylyltransferase
GDMGHCMF_00442 0.0 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
GDMGHCMF_00443 5.31e-90 def_1 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
GDMGHCMF_00444 5.15e-100 - - - K - - - DNA-binding transcription factor activity
GDMGHCMF_00445 0.0 lmrA1 - - V ko:K02021,ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
GDMGHCMF_00446 0.0 lmrA2 - - V ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
GDMGHCMF_00447 1.07e-56 - - - K - - - Acetyltransferase (GNAT) family
GDMGHCMF_00448 9.14e-101 sptS - - T - - - Histidine kinase
GDMGHCMF_00449 3.95e-168 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
GDMGHCMF_00450 9.6e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
GDMGHCMF_00451 1.67e-206 yitL - - S ko:K00243 - ko00000 Protein conserved in bacteria
GDMGHCMF_00452 3.3e-47 yozE - - S - - - Belongs to the UPF0346 family
GDMGHCMF_00453 1.94e-174 usp 3.5.1.104, 3.5.1.28 CBM50 S ko:K15125,ko:K17733,ko:K21449,ko:K21471,ko:K22278,ko:K22409 ko05133,map05133 ko00000,ko00001,ko00536,ko01000,ko01002,ko01011,ko02000 pathogenesis
GDMGHCMF_00454 1.17e-58 sip - - M - - - LysM domain protein
GDMGHCMF_00455 4.56e-244 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
GDMGHCMF_00460 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GDMGHCMF_00461 7.58e-213 - - - K - - - transcriptional regulator (lysR family)
GDMGHCMF_00462 6.68e-238 coiA - - S ko:K06198 - ko00000 Competence protein
GDMGHCMF_00463 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
GDMGHCMF_00464 9.34e-162 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-Methyltransferase
GDMGHCMF_00465 4.09e-217 prsA 3.1.3.16, 5.2.1.8 - O ko:K01802,ko:K03769,ko:K07533,ko:K20074 - ko00000,ko01000,ko01009,ko03110 peptidyl-prolyl cis-trans isomerase activity
GDMGHCMF_00466 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GDMGHCMF_00467 6.41e-27 - - - M - - - GBS Bsp-like repeat
GDMGHCMF_00468 8.97e-294 - 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
GDMGHCMF_00469 1.9e-188 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
GDMGHCMF_00470 5.55e-288 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 mutations do not affect methionine salvage in vivo however
GDMGHCMF_00471 7.87e-243 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GDMGHCMF_00472 3.45e-284 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GDMGHCMF_00473 5.29e-157 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
GDMGHCMF_00474 1.71e-262 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
GDMGHCMF_00475 1.3e-186 icaB - - G - - - deacetylase
GDMGHCMF_00476 3.86e-299 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
GDMGHCMF_00477 2.39e-194 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
GDMGHCMF_00478 1.27e-193 rarD - - S ko:K05786 - ko00000,ko02000 Transporter
GDMGHCMF_00480 9.46e-17 coiA - - S ko:K06198 - ko00000 Competence protein
GDMGHCMF_00481 8.53e-136 - - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GDMGHCMF_00482 2.01e-96 - 2.3.1.128, 5.2.1.8 - J ko:K03768,ko:K03790 - ko00000,ko01000,ko03009,ko03110 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GDMGHCMF_00483 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
GDMGHCMF_00484 2.91e-23 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GDMGHCMF_00485 1.66e-155 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
GDMGHCMF_00486 1.15e-98 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 ATP synthase F(0) sector subunit b
GDMGHCMF_00487 7.09e-113 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GDMGHCMF_00488 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GDMGHCMF_00489 1.68e-197 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GDMGHCMF_00490 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GDMGHCMF_00491 1.65e-76 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
GDMGHCMF_00492 1.86e-288 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
GDMGHCMF_00493 9.17e-285 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GDMGHCMF_00494 7.06e-170 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GDMGHCMF_00495 6.9e-142 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GDMGHCMF_00496 3.72e-205 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 dna polymerase iii
GDMGHCMF_00497 1.07e-172 yaaT - - S - - - stage 0 sporulation protein
GDMGHCMF_00498 2.84e-73 yabA - - L - - - Involved in initiation control of chromosome replication
GDMGHCMF_00499 1.71e-204 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GDMGHCMF_00500 3.76e-286 amt - - P ko:K03320 - ko00000,ko02000 Ammonium Transporter
GDMGHCMF_00501 3.48e-66 glnB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
GDMGHCMF_00502 3.1e-138 mur1 - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 mannosyl-glycoprotein
GDMGHCMF_00503 1.05e-186 XK27_04800 - - S - - - Sucrose-6F-phosphate phosphohydrolase
GDMGHCMF_00504 7.68e-82 yjbB - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
GDMGHCMF_00505 5e-274 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
GDMGHCMF_00506 3.42e-36 - - - S - - - membrane
GDMGHCMF_00507 1.36e-91 - - - S - - - membrane
GDMGHCMF_00508 9.65e-79 - - - S - - - membrane
GDMGHCMF_00509 2.48e-226 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
GDMGHCMF_00510 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
GDMGHCMF_00511 1.42e-52 ynzC - - S - - - UPF0291 protein
GDMGHCMF_00512 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 permease
GDMGHCMF_00514 3.72e-29 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
GDMGHCMF_00515 1.4e-61 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
GDMGHCMF_00516 3.27e-43 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
GDMGHCMF_00517 6.88e-95 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
GDMGHCMF_00518 2.29e-64 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
GDMGHCMF_00519 1.5e-180 ppiA 5.2.1.8 - O ko:K01802,ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 ko00000,ko00001,ko01000,ko03110,ko04147 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GDMGHCMF_00523 4.06e-214 lysR - - K - - - transcriptional regulator (lysR family)
GDMGHCMF_00524 4.01e-100 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GDMGHCMF_00525 4.03e-207 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
GDMGHCMF_00526 2.72e-114 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GDMGHCMF_00527 2.02e-288 pyrP - - F ko:K02824 - ko00000,ko02000 uracil Permease
GDMGHCMF_00528 8.28e-222 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
GDMGHCMF_00529 6.49e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 carbamoyl-phosphate synthetase glutamine chain
GDMGHCMF_00530 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 carbamoyl-phosphate synthetase ammonia chain
GDMGHCMF_00531 3.65e-172 - - - S - - - Putative SAM-dependent methyltransferase
GDMGHCMF_00532 1.1e-46 - - - V - - - efflux transmembrane transporter activity
GDMGHCMF_00533 1.07e-44 - - - V ko:K02004 - ko00000,ko00002,ko02000 efflux transmembrane transporter activity
GDMGHCMF_00534 4.02e-38 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 efflux transmembrane transporter activity
GDMGHCMF_00535 4e-100 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GDMGHCMF_00536 7.29e-70 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
GDMGHCMF_00537 1.18e-137 - - - L ko:K07485 - ko00000 Transposase
GDMGHCMF_00538 2.36e-143 - - - L ko:K07485 - ko00000 Transposase
GDMGHCMF_00539 1.25e-23 - - - L - - - Integrase core domain
GDMGHCMF_00540 1.62e-152 - - - V ko:K02003 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
GDMGHCMF_00541 9.49e-223 hrtB - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
GDMGHCMF_00544 1.16e-127 - - - S - - - MucBP domain
GDMGHCMF_00545 7.31e-61 - - - M - - - YSIRK type signal peptide
GDMGHCMF_00546 0.0 - - - M - - - the current gene model (or a revised gene model) may contain a
GDMGHCMF_00548 1.13e-36 XK27_00530 - - M - - - CHAP domain protein
GDMGHCMF_00549 2.83e-134 - - - K - - - Transcriptional regulator, AbiEi antitoxin
GDMGHCMF_00550 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
GDMGHCMF_00551 5.12e-38 - - - K ko:K02051 - ko00000,ko00002,ko02000 DNA-binding transcription factor activity
GDMGHCMF_00552 0.0 msbA_1 - - V ko:K18887 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
GDMGHCMF_00553 0.0 lmrA - - V ko:K06147,ko:K18888 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
GDMGHCMF_00554 3.38e-252 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GDMGHCMF_00555 3.65e-158 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
GDMGHCMF_00556 7.93e-250 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
GDMGHCMF_00557 5.22e-37 XK27_00085 - - K ko:K07729 - ko00000,ko03000 Transcriptional
GDMGHCMF_00559 8.08e-187 - - - F - - - Phosphorylase superfamily
GDMGHCMF_00560 1.79e-146 - - - S - - - VIT family
GDMGHCMF_00561 4.3e-169 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
GDMGHCMF_00562 5.81e-33 hipO2 - - E ko:K01436,ko:K21613 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
GDMGHCMF_00563 7.24e-229 hipO2 - - E ko:K01436,ko:K21613 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
GDMGHCMF_00564 1.29e-24 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 alanine dehydrogenase activity
GDMGHCMF_00565 2.72e-58 ald 1.4.1.1 - C ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
GDMGHCMF_00566 4.75e-316 merA - - C - - - Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GDMGHCMF_00567 3.51e-131 - - - J ko:K09962 - ko00000 protein conserved in bacteria
GDMGHCMF_00568 9.14e-186 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
GDMGHCMF_00569 1.41e-216 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
GDMGHCMF_00570 9.12e-217 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 GHMP kinases N terminal domain
GDMGHCMF_00571 1.03e-240 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
GDMGHCMF_00572 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GDMGHCMF_00573 2.89e-123 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 AdP-ribose pyrophosphatase
GDMGHCMF_00574 6.01e-41 - - - - - - - -
GDMGHCMF_00575 2.99e-151 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GDMGHCMF_00576 8.68e-35 - - - M ko:K02460 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02044 domain protein
GDMGHCMF_00577 3.3e-88 - - - M ko:K02460 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02044 domain protein
GDMGHCMF_00578 8.17e-242 dgs 2.4.1.208 GT4 M ko:K13677 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
GDMGHCMF_00579 0.0 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
GDMGHCMF_00580 5.47e-29 - - - - - - - -
GDMGHCMF_00581 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GDMGHCMF_00582 1.06e-40 - - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
GDMGHCMF_00583 5.54e-210 - - - S - - - Protein of unknown function (DUF3114)
GDMGHCMF_00584 6.8e-28 - - - S - - - Protein of unknown function (DUF3114)
GDMGHCMF_00585 1.54e-146 hly-III - - K ko:K11068 - ko00000,ko02042 protein, Hemolysin III
GDMGHCMF_00586 4.44e-291 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
GDMGHCMF_00587 3.13e-279 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 synthase
GDMGHCMF_00588 6.02e-213 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GDMGHCMF_00589 4.06e-118 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GDMGHCMF_00590 2.97e-30 - - - - - - - -
GDMGHCMF_00591 1.47e-286 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GDMGHCMF_00592 6.75e-144 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
GDMGHCMF_00593 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
GDMGHCMF_00594 7.32e-226 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 Homocysteine
GDMGHCMF_00595 5.22e-41 - - - S - - - Domain of unknown function (DUF1912)
GDMGHCMF_00596 7.76e-21 - - - L - - - Helix-hairpin-helix DNA-binding motif class 1
GDMGHCMF_00597 3.51e-137 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
GDMGHCMF_00598 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GDMGHCMF_00599 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GDMGHCMF_00600 2.38e-253 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
GDMGHCMF_00601 1.4e-21 - - - S - - - Protein of unknown function (DUF2969)
GDMGHCMF_00604 7.59e-264 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 ribosomal protein S1
GDMGHCMF_00607 2.58e-131 - - - S - - - Domain of Unknown Function with PDB structure (DUF3862)
GDMGHCMF_00608 1.37e-87 - - - M - - - Pfam SNARE associated Golgi protein
GDMGHCMF_00609 1.81e-293 murN - - V ko:K12554 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01011 FemAB family
GDMGHCMF_00610 4.44e-06 - - - S - - - oxidoreductase
GDMGHCMF_00611 4.91e-46 - - - S - - - oxidoreductase
GDMGHCMF_00612 4.61e-132 - - - S - - - oxidoreductase
GDMGHCMF_00613 1.46e-61 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
GDMGHCMF_00614 1.46e-106 XK27_09440 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
GDMGHCMF_00615 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
GDMGHCMF_00616 5.71e-241 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GDMGHCMF_00617 9.51e-47 ykuJ - - S - - - protein conserved in bacteria
GDMGHCMF_00619 3.24e-151 - - - P ko:K02029 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GDMGHCMF_00620 2.12e-167 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 abc transporter atp-binding protein
GDMGHCMF_00621 1.67e-99 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain protein
GDMGHCMF_00622 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
GDMGHCMF_00623 9.87e-12 - - - - - - - -
GDMGHCMF_00624 1.27e-135 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
GDMGHCMF_00625 2.97e-60 - - - K ko:K20374 ko02024,map02024 ko00000,ko00001,ko03000 sequence-specific DNA binding
GDMGHCMF_00626 7.96e-45 yugF - - I - - - carboxylic ester hydrolase activity
GDMGHCMF_00627 8.11e-31 - - - I - - - Alpha/beta hydrolase family
GDMGHCMF_00628 3.44e-202 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GDMGHCMF_00629 2.39e-190 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GDMGHCMF_00630 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 penicillin-binding protein
GDMGHCMF_00631 1.85e-136 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GDMGHCMF_00632 3.21e-171 licT - - K ko:K03488 - ko00000,ko03000 antiterminator
GDMGHCMF_00633 6.25e-112 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GDMGHCMF_00634 1.41e-84 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
GDMGHCMF_00635 1.16e-212 era - - M ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GDMGHCMF_00636 1.16e-199 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
GDMGHCMF_00637 3.66e-135 coaE 2.7.1.24 - H ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GDMGHCMF_00638 5.68e-279 pmrA - - EGP ko:K08161 - ko00000,ko02000 Major Facilitator
GDMGHCMF_00639 1.5e-44 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
GDMGHCMF_00640 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
GDMGHCMF_00641 1.15e-104 smpB - - O ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
GDMGHCMF_00642 0.0 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GDMGHCMF_00643 2.38e-84 yugI - - J ko:K07570 - ko00000 RNA binding protein, contains ribosomal protein S1 domain
GDMGHCMF_00644 1.85e-263 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Belongs to the peptidase M24B family
GDMGHCMF_00645 4.61e-227 ccpA - - K ko:K02529 - ko00000,ko03000 Catabolite control protein A
GDMGHCMF_00646 7.56e-244 XK27_07735 - - S - - - YjbR
GDMGHCMF_00647 1.82e-56 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
GDMGHCMF_00648 1.15e-77 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
GDMGHCMF_00649 2.78e-79 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
GDMGHCMF_00650 9.11e-96 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
GDMGHCMF_00651 1.68e-312 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
GDMGHCMF_00652 1.83e-33 WQ51_00785 - - - - - - -
GDMGHCMF_00653 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
GDMGHCMF_00654 3.56e-281 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
GDMGHCMF_00655 6.61e-157 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
GDMGHCMF_00656 8.16e-206 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GDMGHCMF_00657 5.41e-253 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GDMGHCMF_00658 1.29e-279 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GDMGHCMF_00659 4.34e-261 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
GDMGHCMF_00660 5.81e-69 XK26_04240 - - S - - - Belongs to the UPF0342 family
GDMGHCMF_00661 1.21e-218 hicD2 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
GDMGHCMF_00662 2.81e-296 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
GDMGHCMF_00663 2.28e-113 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GDMGHCMF_00664 1.4e-196 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
GDMGHCMF_00665 0.0 msrR - - K - - - Transcriptional regulator
GDMGHCMF_00666 5.53e-197 ydiA - - P ko:K03304,ko:K11041 ko05150,map05150 ko00000,ko00001,ko02000,ko02042 C4-dicarboxylate transporter malic acid transport protein
GDMGHCMF_00667 3.83e-257 - - - I - - - acyl-CoA dehydrogenase
GDMGHCMF_00668 5.21e-126 mip - - S - - - hydroperoxide reductase activity
GDMGHCMF_00669 0.0 rumA 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GDMGHCMF_00670 5.48e-31 - - - - - - - -
GDMGHCMF_00671 4.27e-184 repA - - S - - - Replication initiator protein A
GDMGHCMF_00672 0.0 hpaIIM 2.1.1.37 - H ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 cytosine-specific methyltransferase
GDMGHCMF_00673 1.62e-96 XK27_00590 - - - - - - -
GDMGHCMF_00674 4.29e-63 - - - - - - - -
GDMGHCMF_00675 3.82e-51 - - - - - - - -
GDMGHCMF_00676 4.5e-121 - 3.4.11.19 - V ko:K01266,ko:K07052 - ko00000,ko01000,ko01002 CAAX protease self-immunity
GDMGHCMF_00677 3.11e-106 - - - - - - - -
GDMGHCMF_00678 0.0 XK27_00565 - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 COG3505 Type IV secretory pathway, VirD4 components
GDMGHCMF_00679 2.55e-46 XK27_00560 - - - - - - -
GDMGHCMF_00680 1.02e-178 XK27_00555 - - - - - - -
GDMGHCMF_00681 5.25e-72 XK27_00550 - - S - - - PrgI family protein
GDMGHCMF_00682 0.0 - - - U - - - 'COG3451 Type IV secretory pathway, VirB4 components'
GDMGHCMF_00683 0.0 XK27_00530 - - M - - - CHAP domain protein
GDMGHCMF_00685 0.0 XK27_00515 - - D - - - Glucan-binding protein C
GDMGHCMF_00686 1.52e-08 XK27_00510 - - - - - - -
GDMGHCMF_00687 5.34e-115 - - - - - - - -
GDMGHCMF_00688 0.0 XK27_00500 - - L - - - the current gene model (or a revised gene model) may contain a
GDMGHCMF_00689 3.46e-55 - - - - - - - -
GDMGHCMF_00690 1.09e-43 - - - - - - - -
GDMGHCMF_00692 6.58e-69 salB - - V ko:K20385 ko02024,map02024 ko00000,ko00001 Domain of unknown function (DUF4135)
GDMGHCMF_00693 0.0 salB - - V ko:K20385 ko02024,map02024 ko00000,ko00001 Domain of unknown function (DUF4135)
GDMGHCMF_00694 0.0 lanT - - V ko:K06148,ko:K13409,ko:K20344,ko:K20386 ko02010,ko02024,ko04626,map02010,map02024,map04626 ko00000,ko00001,ko00002,ko02000,ko02044 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
GDMGHCMF_00695 2.09e-212 spaF - - V ko:K01990,ko:K20459,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
GDMGHCMF_00696 2e-154 - - - S - - - ABC-2 family transporter protein
GDMGHCMF_00697 2.89e-161 - - - - - - - -
GDMGHCMF_00698 0.0 - - - T ko:K14988 ko02020,map02020 ko00000,ko00001,ko00002,ko01001,ko02022 Histidine kinase
GDMGHCMF_00699 3.44e-132 salR - - KT ko:K14989 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator, receiver
GDMGHCMF_00701 1.52e-43 blpT - - - - - - -
GDMGHCMF_00702 2.15e-126 - - - - - - - -
GDMGHCMF_00703 4.16e-240 - - - L - - - Protein of unknown function (DUF3991)
GDMGHCMF_00704 5.84e-34 - - - - - - - -
GDMGHCMF_00705 1.16e-68 - - - - - - - -
GDMGHCMF_00706 6.1e-45 - - - - - - - -
GDMGHCMF_00707 7.79e-58 - - - - - - - -
GDMGHCMF_00708 9.23e-73 - - - - - - - -
GDMGHCMF_00709 0.0 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GDMGHCMF_00711 6.04e-156 - - - K - - - DNA-binding helix-turn-helix protein
GDMGHCMF_00712 0.0 - - - L - - - AAA ATPase domain
GDMGHCMF_00713 7.3e-227 - - - L - - - AAA domain
GDMGHCMF_00714 1.09e-74 - - - - - - - -
GDMGHCMF_00715 1.13e-77 - - - S - - - Bacterial mobilisation protein (MobC)
GDMGHCMF_00716 0.0 - - - U - - - COG3843 Type IV secretory pathway, VirD2 components (relaxase)
GDMGHCMF_00718 3.08e-11 - - - M - - - Bacterial lipoprotein
GDMGHCMF_00719 5.39e-78 - - - S - - - Protein of unknown function (DUF1722)
GDMGHCMF_00720 1.18e-83 yqeB - - S - - - Pyrimidine dimer DNA glycosylase
GDMGHCMF_00722 2.51e-44 - - - - - - - -
GDMGHCMF_00723 7.8e-35 - - - S - - - CAAX protease self-immunity
GDMGHCMF_00724 4.48e-35 - - - E - - - GDSL-like Lipase/Acylhydrolase
GDMGHCMF_00725 3.1e-124 - - - - - - - -
GDMGHCMF_00726 0.0 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
GDMGHCMF_00727 1.32e-220 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GDMGHCMF_00728 2.42e-70 - - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GDMGHCMF_00729 1.31e-246 - - - S - - - CRISPR-associated protein Csn2 subfamily St
GDMGHCMF_00730 3.82e-188 XK27_03010 - - S ko:K08986 - ko00000 TIGR03943 family
GDMGHCMF_00731 4.06e-193 XK27_03015 - - S ko:K07089 - ko00000 permease
GDMGHCMF_00733 0.0 tex - - K ko:K06959 - ko00000 Transcriptional accessory protein
GDMGHCMF_00734 4.88e-54 WQ51_05770 - - KT - - - PspC domain
GDMGHCMF_00735 2.26e-215 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GDMGHCMF_00736 4.15e-188 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GDMGHCMF_00737 2e-27 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GDMGHCMF_00738 2.17e-87 ytxH - - S - - - General stress protein
GDMGHCMF_00740 1.44e-227 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
GDMGHCMF_00741 0.0 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
GDMGHCMF_00742 2.56e-111 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 biotin synthase
GDMGHCMF_00744 2.97e-45 XK27_12190 - - S - - - protein conserved in bacteria
GDMGHCMF_00745 3.69e-296 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
GDMGHCMF_00747 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
GDMGHCMF_00748 1.02e-19 - - - M - - - LysM domain
GDMGHCMF_00749 8.26e-57 - - - M - - - LysM domain
GDMGHCMF_00750 4.62e-71 - - - M - - - LysM domain
GDMGHCMF_00752 4.26e-220 - - - S ko:K07025 - ko00000 hydrolase
GDMGHCMF_00753 1.02e-149 pgm - - G - - - Phosphoglycerate mutase
GDMGHCMF_00754 7.14e-105 - - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GDMGHCMF_00755 1.2e-197 - 3.5.1.28 - M ko:K01447,ko:K07273 - ko00000,ko01000 Glycosyl hydrolase, family 25
GDMGHCMF_00756 8.02e-36 - - - P - - - Hemerythrin HHE cation binding domain protein
GDMGHCMF_00757 1.64e-144 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GDMGHCMF_00758 4.51e-14 - - - S - - - Protein of unknown function (DUF2974)
GDMGHCMF_00759 6.57e-46 - - - S - - - Protein of unknown function (DUF2974)
GDMGHCMF_00760 2.06e-60 - - - S - - - Protein of unknown function (DUF2974)
GDMGHCMF_00761 3.75e-166 sdh - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
GDMGHCMF_00762 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
GDMGHCMF_00763 1.37e-142 - - - - ko:K15051 - ko00000 -
GDMGHCMF_00764 6e-291 - - - S - - - SIR2-like domain
GDMGHCMF_00765 0.0 - - - S ko:K06915 - ko00000 Domain of unknown function DUF87
GDMGHCMF_00766 5.11e-170 - - - V - - - Type I restriction modification DNA specificity domain
GDMGHCMF_00767 1.21e-135 - - - - - - - -
GDMGHCMF_00768 6.3e-158 - - - S - - - Protein conserved in bacteria
GDMGHCMF_00769 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
GDMGHCMF_00770 8.89e-28 - - - S - - - PD-(D/E)XK nuclease family transposase
GDMGHCMF_00771 9.68e-18 spd - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
GDMGHCMF_00772 6.96e-54 spd - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
GDMGHCMF_00773 3.44e-100 spd - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
GDMGHCMF_00774 4.21e-118 lemA - - S ko:K03744 - ko00000 LemA family
GDMGHCMF_00775 3.84e-186 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
GDMGHCMF_00776 8.61e-97 - - - S ko:K16927 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score
GDMGHCMF_00777 9.85e-69 - - - S - - - Domain of unknown function (DUF4430)
GDMGHCMF_00778 0.0 ppc 4.1.1.31 - H ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GDMGHCMF_00779 1.29e-234 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
GDMGHCMF_00780 2.63e-142 sodA 1.15.1.1 - C ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
GDMGHCMF_00781 1.31e-233 - - - V - - - D-alanyl-D-alanine carboxypeptidase
GDMGHCMF_00782 6.39e-150 pppA 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
GDMGHCMF_00783 1.11e-118 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
GDMGHCMF_00784 1.95e-103 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
GDMGHCMF_00785 6.79e-32 yqgQ - - S - - - protein conserved in bacteria
GDMGHCMF_00786 6.85e-228 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
GDMGHCMF_00787 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
GDMGHCMF_00788 9.4e-13 - - - S - - - Protein of unknown function (DUF3165)
GDMGHCMF_00789 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GDMGHCMF_00790 3.84e-251 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GDMGHCMF_00791 5.65e-228 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
GDMGHCMF_00792 3.84e-312 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
GDMGHCMF_00793 1.2e-299 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GDMGHCMF_00794 1.1e-156 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GDMGHCMF_00795 1.58e-119 sepF - - D ko:K09772 - ko00000,ko03036 cell septum assembly
GDMGHCMF_00796 7.35e-46 yggT - - D ko:K02221 - ko00000,ko02044 integral membrane protein
GDMGHCMF_00797 9.63e-181 ylmH - - T ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 S4 RNA-binding domain
GDMGHCMF_00798 2.12e-179 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division protein DivIVA
GDMGHCMF_00799 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GDMGHCMF_00800 8.35e-54 - - - L - - - the current gene model (or a revised gene model) may contain a frame shift
GDMGHCMF_00801 6.08e-276 mntH_2 - - P - - - Mn2 and Fe2 transporters of the NRAMP family
GDMGHCMF_00802 5.46e-59 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 50S ribosomal protein L31
GDMGHCMF_00803 1.93e-217 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
GDMGHCMF_00804 2.04e-225 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 domain protein
GDMGHCMF_00805 7.83e-197 gst - - O ko:K11209 - ko00000,ko01000 Glutathione S-transferase
GDMGHCMF_00806 1.3e-239 add 3.5.4.2, 3.5.4.4 - F ko:K01488,ko:K02029,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GDMGHCMF_00807 2.65e-145 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
GDMGHCMF_00808 1.31e-246 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GDMGHCMF_00809 4.65e-192 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
GDMGHCMF_00810 1.46e-139 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
GDMGHCMF_00811 4.84e-296 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GDMGHCMF_00812 1.13e-223 - - - S - - - 37-kD nucleoid-associated bacterial protein
GDMGHCMF_00813 2.98e-135 pvaA - - M ko:K02395 - ko00000,ko02035 lytic transglycosylase activity
GDMGHCMF_00814 0.0 yfiB1 - - V ko:K06147,ko:K06148 - ko00000,ko02000 abc transporter atp-binding protein
GDMGHCMF_00815 0.0 XK27_10035 - - V ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
GDMGHCMF_00816 1.01e-14 - - - S - - - D-Ala-teichoic acid biosynthesis protein
GDMGHCMF_00817 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GDMGHCMF_00818 1.05e-294 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Membrane protein involved in D-alanine export
GDMGHCMF_00819 8.28e-47 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GDMGHCMF_00820 2.87e-307 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GDMGHCMF_00821 8.86e-25 - - - L ko:K07497 - ko00000 Integrase core domain protein
GDMGHCMF_00822 2.32e-61 - - - L ko:K07483 - ko00000 transposase activity
GDMGHCMF_00823 0.0 - 3.6.3.2, 3.6.3.6, 3.6.3.8 - P ko:K01531,ko:K01535,ko:K01537 ko00190,map00190 ko00000,ko00001,ko01000 cation transport ATPase
GDMGHCMF_00824 0.0 pabB 2.6.1.85, 4.1.3.38 - EH ko:K01665,ko:K03342,ko:K13950 ko00790,map00790 ko00000,ko00001,ko01000,ko01007 component I
GDMGHCMF_00826 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GDMGHCMF_00827 3.09e-211 metF 1.5.1.20 - C ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 reductase
GDMGHCMF_00828 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
GDMGHCMF_00829 4.34e-120 - - - S - - - ECF transporter, substrate-specific component
GDMGHCMF_00830 1.49e-120 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GDMGHCMF_00831 6.6e-158 coaB 6.3.2.5 - H ko:K21977 ko00770,map00770 ko00000,ko00001,ko00002,ko01000 Phosphopantothenate-cysteine ligase
GDMGHCMF_00832 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
GDMGHCMF_00833 3.26e-152 ciaR - - T ko:K14983 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GDMGHCMF_00834 5.64e-298 ciaH 2.7.13.3 - T ko:K14982 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GDMGHCMF_00835 2.32e-39 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 rRNA binding
GDMGHCMF_00836 4.78e-220 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
GDMGHCMF_00837 7.57e-135 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase small domain protein
GDMGHCMF_00838 6.67e-18 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
GDMGHCMF_00839 3.32e-42 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
GDMGHCMF_00840 7.88e-40 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
GDMGHCMF_00841 3.03e-33 pdp 2.4.2.2, 2.4.2.4 - F ko:K00756,ko:K00758 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 ko00000,ko00001,ko01000 phosphorylase activity
GDMGHCMF_00842 1.57e-103 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GDMGHCMF_00843 5.17e-86 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
GDMGHCMF_00844 5.75e-244 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
GDMGHCMF_00845 0.0 mglA 3.6.3.17 - S ko:K02056,ko:K06400 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GDMGHCMF_00846 9.61e-247 mglC - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
GDMGHCMF_00847 1.93e-216 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
GDMGHCMF_00848 3.2e-157 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
GDMGHCMF_00849 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
GDMGHCMF_00850 1.55e-105 ypmB - - S - - - Protein conserved in bacteria
GDMGHCMF_00851 4.3e-276 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
GDMGHCMF_00852 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
GDMGHCMF_00855 5.64e-17 - - - L ko:K07485 - ko00000 Transposase
GDMGHCMF_00856 1.84e-83 aldR 3.5.99.10 - J ko:K09022 - ko00000,ko01000 endoribonuclease L-PSP
GDMGHCMF_00857 1.52e-158 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GDMGHCMF_00858 4.76e-105 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
GDMGHCMF_00859 8.37e-171 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
GDMGHCMF_00860 1.11e-121 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
GDMGHCMF_00861 2.32e-23 - - - D - - - nuclear chromosome segregation
GDMGHCMF_00862 1.73e-172 yejC - - S - - - cyclic nucleotide-binding protein
GDMGHCMF_00863 2e-207 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
GDMGHCMF_00864 3.55e-231 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
GDMGHCMF_00865 1.4e-206 whiA - - K ko:K09762 - ko00000 May be required for sporulation
GDMGHCMF_00866 1.83e-208 pepD - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
GDMGHCMF_00867 3.55e-14 pepD - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
GDMGHCMF_00868 1.21e-36 - - - L ko:K07483 - ko00000 transposase activity
GDMGHCMF_00870 5.59e-37 - - - - - - - -
GDMGHCMF_00871 1.47e-41 - - - K - - - Cold shock protein domain
GDMGHCMF_00872 0.0 copB 3.6.3.4 - P ko:K01533 - ko00000,ko01000 P-type ATPase
GDMGHCMF_00873 1.1e-32 B4168_4126 - - L ko:K07493 - ko00000 Transposase
GDMGHCMF_00874 1.25e-51 hsdS 2.1.1.72, 3.1.21.3 - V ko:K01154,ko:K07317 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain
GDMGHCMF_00875 1.34e-144 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
GDMGHCMF_00876 2.43e-187 glcU - - U ko:K05340 - ko00000,ko02000 sugar transport
GDMGHCMF_00877 5.25e-08 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
GDMGHCMF_00878 3.02e-98 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 HsdM N-terminal domain
GDMGHCMF_00879 3.22e-88 XK27_10720 - - D - - - peptidase activity
GDMGHCMF_00880 0.0 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
GDMGHCMF_00882 4.53e-219 yeiH - - S - - - Membrane
GDMGHCMF_00883 1.16e-127 - - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 muramidase
GDMGHCMF_00884 4.4e-45 - - - L ko:K07483 - ko00000 transposase activity
GDMGHCMF_00885 1.79e-213 cpsY - - K - - - Transcriptional regulator
GDMGHCMF_00886 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
GDMGHCMF_00887 3.68e-75 phnA - - P ko:K06193 ko01120,map01120 ko00000 Alkylphosphonate utilization operon protein PhnA
GDMGHCMF_00888 3.36e-135 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter (Permease
GDMGHCMF_00889 2.15e-145 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 abc transporter atp-binding protein
GDMGHCMF_00890 3.72e-201 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
GDMGHCMF_00891 7.3e-48 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GDMGHCMF_00892 2.31e-141 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GDMGHCMF_00893 1.14e-35 - - - - - - - -
GDMGHCMF_00894 3.41e-21 adhP 1.1.1.1 - C ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
GDMGHCMF_00895 2.45e-103 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
GDMGHCMF_00897 6.93e-28 - - - - - - - -
GDMGHCMF_00898 0.0 sthIR 3.1.21.5 - S ko:K01156 - ko00000,ko01000,ko02048 Type III restriction
GDMGHCMF_00899 0.0 - 2.1.1.72 - L ko:K07316 - ko00000,ko01000,ko02048 Adenine specific DNA methylase Mod
GDMGHCMF_00900 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
GDMGHCMF_00901 6.09e-161 yvoA_2 - - K ko:K03710 - ko00000,ko03000 transcriptional
GDMGHCMF_00902 1.49e-70 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GDMGHCMF_00903 0.0 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GDMGHCMF_00904 4.63e-112 niaX - - - ko:K16788 - ko00000,ko02000 -
GDMGHCMF_00905 1.25e-114 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
GDMGHCMF_00906 1.29e-165 - - - K - - - DNA-binding helix-turn-helix protein
GDMGHCMF_00907 1.46e-203 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GDMGHCMF_00908 6.81e-174 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GDMGHCMF_00909 7.29e-215 - - - GK - - - ROK family
GDMGHCMF_00910 6.69e-202 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
GDMGHCMF_00911 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GDMGHCMF_00912 8.43e-198 - - - S - - - TraX protein
GDMGHCMF_00913 2.41e-156 spaR - - KT ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GDMGHCMF_00914 3.49e-311 - 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
GDMGHCMF_00915 0.0 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GDMGHCMF_00916 8.01e-278 XK27_05470 - - E - - - Methionine synthase
GDMGHCMF_00917 4.41e-95 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
GDMGHCMF_00918 5.79e-62 pspE - - P ko:K03972 - ko00000 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GDMGHCMF_00919 8.45e-26 butA 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 Acetoin reductase
GDMGHCMF_00920 4.8e-48 butA 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 Acetoin reductase
GDMGHCMF_00922 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
GDMGHCMF_00923 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
GDMGHCMF_00924 1.34e-172 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Belongs to the alpha-acetolactate decarboxylase family
GDMGHCMF_00925 9.79e-44 - - - L ko:K07485 - ko00000 Transposase
GDMGHCMF_00926 9.8e-62 - - - L - - - Transposase
GDMGHCMF_00927 5.05e-42 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (Permease
GDMGHCMF_00928 1.93e-66 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (Permease
GDMGHCMF_00929 7.87e-95 - - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
GDMGHCMF_00930 9.28e-15 - - - - - - - -
GDMGHCMF_00931 2.21e-126 - - - K - - - Transcriptional regulator, TetR family
GDMGHCMF_00932 3.04e-203 czcD - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
GDMGHCMF_00933 1.14e-149 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
GDMGHCMF_00934 2e-53 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
GDMGHCMF_00935 7.95e-250 adhB 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Dehydrogenase
GDMGHCMF_00936 2.92e-11 - - - S ko:K06889 - ko00000 Hydrolases of the alpha beta superfamily
GDMGHCMF_00937 1.61e-23 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
GDMGHCMF_00938 2e-102 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
GDMGHCMF_00941 4.01e-186 - - - F - - - Phosphorylase superfamily
GDMGHCMF_00942 1.71e-152 - 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 HAD hydrolase, family IA, variant 1
GDMGHCMF_00943 2.48e-09 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
GDMGHCMF_00944 2.05e-22 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type enterochelin transport system, periplasmic component
GDMGHCMF_00945 3.29e-93 dinF - - V - - - Mate efflux family protein
GDMGHCMF_00946 2.21e-37 dinF - - V - - - drug transmembrane transporter activity
GDMGHCMF_00947 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
GDMGHCMF_00948 0.000353 - - - S - - - TraX protein
GDMGHCMF_00949 9.55e-111 - - - S - - - TraX protein
GDMGHCMF_00950 1.18e-122 thiJ 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1 family
GDMGHCMF_00951 6.89e-189 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
GDMGHCMF_00952 7.98e-225 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
GDMGHCMF_00953 4.86e-234 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GDMGHCMF_00954 2.91e-72 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GDMGHCMF_00955 3.78e-88 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
GDMGHCMF_00956 1.15e-300 - - - M ko:K20345 ko02024,map02024 ko00000,ko00001,ko02000 HlyD family secretion protein
GDMGHCMF_00957 6.57e-305 comA - - V ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
GDMGHCMF_00958 4.85e-170 comA - - V ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
GDMGHCMF_00962 2.51e-62 - - - S - - - Enterocin A Immunity
GDMGHCMF_00966 3.96e-69 - - - - - - - -
GDMGHCMF_00970 7.27e-06 - - - S - - - Bacteriocin class II with double-glycine leader peptide
GDMGHCMF_00971 2.19e-71 ps105 - - - - - - -
GDMGHCMF_00973 9.97e-21 - - - - ko:K20341 ko02024,map02024 ko00000,ko00001 -
GDMGHCMF_00974 1.51e-169 blpT - - - - - - -
GDMGHCMF_00976 2.59e-171 agrA - - KT ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 phosphorelay signal transduction system
GDMGHCMF_00977 3.65e-178 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
GDMGHCMF_00980 2.53e-63 - - - S - - - Psort location Cytoplasmic, score
GDMGHCMF_00981 1.26e-137 - - - S - - - Psort location Cytoplasmic, score
GDMGHCMF_00982 1.76e-164 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
GDMGHCMF_00983 4.34e-145 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GDMGHCMF_00984 1.11e-09 nylA 3.5.1.4 - J ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 amidase activity
GDMGHCMF_00986 0.0 dtpT - - U ko:K03305 - ko00000 POT family
GDMGHCMF_00987 1.12e-153 - - - - - - - -
GDMGHCMF_00988 5.64e-106 sasH 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
GDMGHCMF_00989 7.69e-72 sasH 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
GDMGHCMF_00990 2.3e-135 yfiF3 - - K - - - sequence-specific DNA binding
GDMGHCMF_00991 1.16e-29 bglC - - K - - - Transcriptional regulator
GDMGHCMF_00992 2.92e-315 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GDMGHCMF_00993 3.21e-303 agcS - - E ko:K03310 - ko00000 (Alanine) symporter
GDMGHCMF_00994 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
GDMGHCMF_00995 3.38e-297 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 o-acetylhomoserine
GDMGHCMF_00996 7.29e-65 - - - S - - - haloacid dehalogenase-like hydrolase
GDMGHCMF_00997 1.12e-109 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GDMGHCMF_00998 3.05e-139 hsdS2 - - V - - - Type I restriction modification DNA specificity domain
GDMGHCMF_00999 1.4e-44 M1-755 - - P ko:K09155 - ko00000 Hemerythrin HHE cation binding domain protein
GDMGHCMF_01000 4.46e-299 XK27_04775 - - S ko:K09155 - ko00000 hemerythrin HHE cation binding domain
GDMGHCMF_01001 7.77e-191 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GDMGHCMF_01002 2.19e-219 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
GDMGHCMF_01003 2.93e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
GDMGHCMF_01004 1.35e-56 yktA - - S - - - Belongs to the UPF0223 family
GDMGHCMF_01005 1.62e-181 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
GDMGHCMF_01006 7.15e-315 rsmF - - J - - - NOL1 NOP2 sun family protein
GDMGHCMF_01007 6.62e-199 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 phosphate
GDMGHCMF_01008 6.58e-201 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
GDMGHCMF_01009 1.32e-195 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 phosphate transport system permease
GDMGHCMF_01010 1.24e-191 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GDMGHCMF_01011 9.74e-177 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GDMGHCMF_01012 2.58e-146 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
GDMGHCMF_01013 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
GDMGHCMF_01014 7.01e-245 xerS - - D ko:K04763 - ko00000,ko03036 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
GDMGHCMF_01016 6.64e-234 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
GDMGHCMF_01017 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
GDMGHCMF_01018 0.0 malQ 2.4.1.25 GH77 G ko:K00705 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 4-alpha-glucanotransferase
GDMGHCMF_01019 9.36e-163 malR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
GDMGHCMF_01020 2.84e-151 malX - - G ko:K15770 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GDMGHCMF_01021 1.47e-86 malF - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
GDMGHCMF_01022 1.34e-104 malF - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
GDMGHCMF_01023 1.04e-148 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
GDMGHCMF_01024 2.05e-14 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GDMGHCMF_01025 4.22e-226 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type enterochelin transport system, periplasmic component
GDMGHCMF_01026 5e-174 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
GDMGHCMF_01027 1.98e-211 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GDMGHCMF_01028 1.1e-210 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GDMGHCMF_01029 2.2e-36 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 N-acetylmuramoyl-L-alanine amidase
GDMGHCMF_01030 3.06e-250 - 3.5.1.28 - S ko:K01448,ko:K02395,ko:K21471 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko02035,ko03036 dextransucrase activity
GDMGHCMF_01031 1.35e-65 - 3.5.1.28 - S ko:K01448,ko:K02395,ko:K21471 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko02035,ko03036 dextransucrase activity
GDMGHCMF_01032 0.0 lpdA 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
GDMGHCMF_01033 3.54e-267 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
GDMGHCMF_01034 3.38e-232 acoB 1.2.4.1 - C ko:K00162,ko:K21417 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
GDMGHCMF_01035 3.57e-235 acoA 1.2.4.1 - C ko:K00161,ko:K21416 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
GDMGHCMF_01036 0.0 - - - S - - - the current gene model (or a revised gene model) may contain a frame shift
GDMGHCMF_01037 1.63e-297 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
GDMGHCMF_01038 1.35e-161 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GDMGHCMF_01039 4.47e-276 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GDMGHCMF_01040 6.57e-23 dacA1 3.4.16.4 - M ko:K01286 - ko00000,ko01000 Belongs to the peptidase S11 family
GDMGHCMF_01041 5.96e-29 dacA1 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
GDMGHCMF_01042 3.13e-169 dacA1 3.4.16.4 - M ko:K01286 - ko00000,ko01000 Belongs to the peptidase S11 family
GDMGHCMF_01043 3.05e-200 - - - S - - - Phospholipase, patatin family
GDMGHCMF_01044 4.01e-137 - - - E - - - Lysophospholipase L1 and related esterases
GDMGHCMF_01045 0.0 ubiB - - S ko:K03688 - ko00000 unusual protein kinase
GDMGHCMF_01046 3.55e-52 - - - S - - - granule-associated protein
GDMGHCMF_01047 4.88e-49 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
GDMGHCMF_01048 6.88e-58 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 beta-glucosidase activity
GDMGHCMF_01049 5.68e-126 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
GDMGHCMF_01050 5.38e-36 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 beta-glucosidase activity
GDMGHCMF_01051 6.82e-254 XK27_12525 - - S - - - hmm pf01594
GDMGHCMF_01052 3.03e-113 - - - G - - - Belongs to the phosphoglycerate mutase family
GDMGHCMF_01053 2.45e-44 - - - G - - - Belongs to the phosphoglycerate mutase family
GDMGHCMF_01054 4.71e-122 - - - V - - - VanZ like family
GDMGHCMF_01055 5.29e-301 - - - L ko:K07485 - ko00000 Transposase
GDMGHCMF_01056 1.01e-250 - - - M - - - transferase activity, transferring glycosyl groups
GDMGHCMF_01057 2.44e-228 wefC - - M - - - Stealth protein CR2, conserved region 2
GDMGHCMF_01058 5.19e-277 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
GDMGHCMF_01059 1.83e-178 - - - S - - - Acyltransferase family
GDMGHCMF_01060 7.83e-21 - - - S - - - Acyltransferase family
GDMGHCMF_01061 0.0 wzx - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
GDMGHCMF_01062 4.78e-110 cpsB 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 Capsular polysaccharide biosynthesis protein
GDMGHCMF_01063 0.0 cps4A - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
GDMGHCMF_01064 9.39e-167 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 purine nucleoside phosphorylase
GDMGHCMF_01065 3.09e-117 gat 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 glutamine amidotransferase
GDMGHCMF_01066 4.85e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GDMGHCMF_01067 2.86e-86 - - - S - - - Protein of unknown function (DUF1697)
GDMGHCMF_01068 1.23e-296 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
GDMGHCMF_01069 3.8e-152 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GDMGHCMF_01070 8.25e-10 - - - V - - - Glucan-binding protein C
GDMGHCMF_01071 1.96e-30 - - - V - - - Glucan-binding protein C
GDMGHCMF_01072 1.44e-140 ung2 - - L - - - Uracil-DNA glycosylase
GDMGHCMF_01073 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Dipeptidase
GDMGHCMF_01074 2.78e-37 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
GDMGHCMF_01075 3.04e-91 XK27_03610 - - K - - - Gnat family
GDMGHCMF_01076 7.4e-73 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GDMGHCMF_01077 7.95e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
GDMGHCMF_01078 6.35e-115 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GDMGHCMF_01079 1.61e-153 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
GDMGHCMF_01080 2.68e-39 XK27_09115 - - M - - - LysM domain
GDMGHCMF_01081 8.53e-115 ebsA - - S - - - Family of unknown function (DUF5322)
GDMGHCMF_01082 6.75e-287 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
GDMGHCMF_01083 7.34e-123 sipC 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
GDMGHCMF_01084 5.23e-283 XK27_05225 - - G - - - COG0457 FOG TPR repeat
GDMGHCMF_01085 1.42e-230 XK27_05220 - - S - - - permease
GDMGHCMF_01086 6.84e-118 mutX 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NTP pyrophosphohydrolases including oxidative damage repair enzymes
GDMGHCMF_01087 5.7e-209 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
GDMGHCMF_01088 1.72e-158 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
GDMGHCMF_01089 1.79e-230 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GDMGHCMF_01090 4.87e-260 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GDMGHCMF_01091 2.13e-231 - - - S - - - Calcineurin-like phosphoesterase
GDMGHCMF_01092 5.64e-174 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
GDMGHCMF_01093 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 cation transport ATPase
GDMGHCMF_01094 1.19e-89 ywiB - - S - - - Domain of unknown function (DUF1934)
GDMGHCMF_01095 1.57e-87 XK27_00115 - - K - - - Acetyltransferase GNAT family
GDMGHCMF_01096 2.3e-188 XK27_00835 - - S - - - hydrolases of the HAD superfamily
GDMGHCMF_01097 3.51e-292 femX 2.3.2.10, 2.3.2.16 - V ko:K05363,ko:K11693 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01011 protein involved in methicillin resistance
GDMGHCMF_01099 3.43e-195 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Metal-dependent hydrolases of the beta-lactamase superfamily I
GDMGHCMF_01100 3.82e-315 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GDMGHCMF_01101 2.91e-165 yycF - - KT ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GDMGHCMF_01102 3.37e-174 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
GDMGHCMF_01103 3.14e-190 peb1A - - ET ko:K02030,ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type amino acid transport signal transduction systems, periplasmic component domain
GDMGHCMF_01104 2.28e-156 XK27_07620 - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
GDMGHCMF_01105 2.66e-138 - - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
GDMGHCMF_01106 1.71e-49 - - - L ko:K07485 - ko00000 Transposase
GDMGHCMF_01107 5.14e-29 isp - - L - - - Transposase
GDMGHCMF_01108 4.08e-62 - - - U - - - response to pH
GDMGHCMF_01109 2.49e-223 - - - L ko:K07485 - ko00000 Transposase
GDMGHCMF_01110 2.18e-194 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
GDMGHCMF_01111 4.09e-35 - - - S - - - DNA-directed RNA polymerase subunit beta
GDMGHCMF_01112 3.49e-288 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GDMGHCMF_01114 1.05e-250 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
GDMGHCMF_01115 3.17e-40 - 5.1.3.2 - GM ko:K01784,ko:K21009 ko00052,ko00520,ko01100,ko02025,map00052,map00520,map01100,map02025 ko00000,ko00001,ko00002,ko01000 Psort location CytoplasmicMembrane, score
GDMGHCMF_01116 5.75e-267 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GDMGHCMF_01117 1.32e-220 birA 6.3.4.15 - HK ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
GDMGHCMF_01118 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GDMGHCMF_01119 6.46e-116 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
GDMGHCMF_01120 1.88e-207 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GDMGHCMF_01121 9.42e-28 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
GDMGHCMF_01123 5.73e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
GDMGHCMF_01124 1.76e-278 - - - P - - - chloride
GDMGHCMF_01125 7.36e-55 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 - E ko:K00661,ko:K04092,ko:K04093,ko:K04516,ko:K14170,ko:K14187 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Chorismate mutase
GDMGHCMF_01126 0.0 eriC - - P ko:K03281 - ko00000 Chloride transporter, ClC family
GDMGHCMF_01127 9.99e-98 ykuP - - C ko:K03839 - ko00000 Flavodoxin
GDMGHCMF_01129 1.27e-161 XK27_08875 - - O - - - Zinc-dependent metalloprotease
GDMGHCMF_01130 1.07e-193 estA - CE1 S ko:K03930 - ko00000,ko01000 Putative esterase
GDMGHCMF_01131 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GDMGHCMF_01132 4.26e-171 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
GDMGHCMF_01133 8.47e-185 XK27_08840 - - S ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
GDMGHCMF_01134 7.64e-226 - - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter substrate binding protein
GDMGHCMF_01135 5.6e-17 - - - S - - - Domain of unknown function (DUF4649)
GDMGHCMF_01136 1.29e-14 crpB - - Q - - - the current gene model (or a revised gene model) may contain a frame shift
GDMGHCMF_01137 5.67e-17 crpB - - Q - - - the current gene model (or a revised gene model) may contain a frame shift
GDMGHCMF_01138 5.63e-12 crpB - - Q - - - the current gene model (or a revised gene model) may contain a frame shift
GDMGHCMF_01139 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
GDMGHCMF_01140 3.89e-235 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
GDMGHCMF_01141 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
GDMGHCMF_01142 1.57e-191 XK27_00020 - - J - - - Belongs to the SUA5 family
GDMGHCMF_01143 1.6e-145 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GDMGHCMF_01144 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GDMGHCMF_01145 6.43e-55 ysdA - - L - - - Membrane
GDMGHCMF_01146 2.93e-236 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
GDMGHCMF_01147 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GDMGHCMF_01148 6.9e-166 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GDMGHCMF_01149 3.28e-230 pyrD 1.3.5.2, 1.3.98.1 - F ko:K00226,ko:K00254 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dihydroorotate to orotate
GDMGHCMF_01152 1.54e-52 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
GDMGHCMF_01153 4.53e-119 ypmS - - S - - - Protein conserved in bacteria
GDMGHCMF_01154 3.84e-182 XK27_03630 - - E - - - COG2755 Lysophospholipase L1 and related esterases
GDMGHCMF_01155 1.54e-186 WQ51_01275 - - S - - - DegV family
GDMGHCMF_01156 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
GDMGHCMF_01157 5.98e-95 argR - - K ko:K03402 - ko00000,ko03000 arginine binding
GDMGHCMF_01158 1.96e-194 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
GDMGHCMF_01159 8.34e-197 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
GDMGHCMF_01160 1.72e-40 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease VII activity
GDMGHCMF_01161 1.38e-308 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GDMGHCMF_01163 1.01e-149 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GDMGHCMF_01164 1.75e-160 dnaD - - - ko:K02086 - ko00000 -
GDMGHCMF_01165 4.47e-229 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GDMGHCMF_01166 5.09e-119 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GDMGHCMF_01167 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease recj
GDMGHCMF_01168 3.01e-177 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
GDMGHCMF_01169 2.11e-220 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
GDMGHCMF_01170 1.15e-152 XK27_05445 - - G - - - UDPglucose--hexose-1-phosphate uridylyltransferase
GDMGHCMF_01171 1.16e-285 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GDMGHCMF_01172 3.24e-308 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
GDMGHCMF_01173 1.48e-65 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 - E ko:K01523,ko:K01814,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 phosphoribosyl-ATP diphosphatase activity
GDMGHCMF_01174 6.01e-80 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GDMGHCMF_01175 5.63e-176 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
GDMGHCMF_01176 1.75e-168 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GDMGHCMF_01177 1.21e-143 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GDMGHCMF_01178 2.75e-136 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
GDMGHCMF_01179 1.05e-291 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GDMGHCMF_01180 4.86e-150 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
GDMGHCMF_01181 9.09e-235 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GDMGHCMF_01182 3.93e-248 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GDMGHCMF_01183 2.74e-41 - - - L ko:K07497 - ko00000 Integrase core domain protein
GDMGHCMF_01184 2.15e-49 - - - L ko:K07497 - ko00000 Integrase core domain protein
GDMGHCMF_01185 3.48e-43 - - - L ko:K07497 - ko00000 transposition
GDMGHCMF_01186 2.54e-30 - - - L - - - Transposase
GDMGHCMF_01187 6.33e-47 - - - L ko:K07483 - ko00000 transposase activity
GDMGHCMF_01188 2.92e-58 - - - L - - - Transposase
GDMGHCMF_01189 7.26e-191 - - - L ko:K07485 - ko00000 Transposase
GDMGHCMF_01190 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GDMGHCMF_01191 3.68e-125 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
GDMGHCMF_01192 1.21e-303 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
GDMGHCMF_01193 6.7e-301 - 3.5.2.6 - V ko:K01467 ko01501,ko02020,map01501,map02020 ko00000,ko00001,ko00002,ko01000 Beta-lactamase enzyme family
GDMGHCMF_01194 1.94e-05 - - - - - - - -
GDMGHCMF_01195 3.9e-79 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
GDMGHCMF_01196 3.77e-53 yabO - - J - - - Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
GDMGHCMF_01197 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GDMGHCMF_01198 5.18e-134 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
GDMGHCMF_01199 3.04e-258 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
GDMGHCMF_01200 1.4e-40 yyzM - - S - - - Protein conserved in bacteria
GDMGHCMF_01201 8.68e-257 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
GDMGHCMF_01202 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GDMGHCMF_01203 8.89e-170 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
GDMGHCMF_01204 1.85e-254 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
GDMGHCMF_01205 1.72e-109 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GDMGHCMF_01206 8.59e-148 yoaK - - S - - - Protein of unknown function (DUF1275)
GDMGHCMF_01210 0.0 XK27_10405 - - S - - - Bacterial membrane protein YfhO
GDMGHCMF_01211 0.0 ykpA - - S - - - abc transporter atp-binding protein
GDMGHCMF_01212 2.69e-186 XK27_10395 - - S - - - membrane
GDMGHCMF_01213 1.12e-242 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
GDMGHCMF_01214 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
GDMGHCMF_01215 2.11e-251 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GDMGHCMF_01216 1.55e-61 yaaA - - S - - - S4 domain protein YaaA
GDMGHCMF_01217 3.56e-200 albE - - S - - - Peptidase M16
GDMGHCMF_01218 8.2e-54 albE - - S - - - Peptidase M16
GDMGHCMF_01219 9.55e-303 ymfH - - S - - - Peptidase M16
GDMGHCMF_01220 8.84e-185 ymfM - - S ko:K15539 - ko00000 sequence-specific DNA binding
GDMGHCMF_01221 1.73e-114 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GDMGHCMF_01222 1.06e-192 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GDMGHCMF_01223 1.75e-193 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GDMGHCMF_01224 2.02e-175 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GDMGHCMF_01225 8.9e-119 lytE - - M - - - LysM domain protein
GDMGHCMF_01226 3.87e-123 isaA - - M - - - Immunodominant staphylococcal antigen A
GDMGHCMF_01227 0.0 - - - S - - - Bacterial membrane protein, YfhO
GDMGHCMF_01228 1.23e-274 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
GDMGHCMF_01229 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
GDMGHCMF_01230 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
GDMGHCMF_01231 1.02e-97 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
GDMGHCMF_01232 6.11e-311 dnaC 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
GDMGHCMF_01233 2.51e-62 WQ51_01655 - - S - - - Biofilm formation stimulator VEG
GDMGHCMF_01234 3.42e-140 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GDMGHCMF_01236 1.48e-68 ypaA - - S ko:K08987 - ko00000 membrane
GDMGHCMF_01237 1.56e-121 XK27_06935 - - K - - - transcriptional regulator
GDMGHCMF_01238 1.03e-243 XK27_06930 - - V ko:K01421 - ko00000 domain protein
GDMGHCMF_01239 2.44e-29 - - - S - - - Putative adhesin
GDMGHCMF_01240 3.67e-78 - - - S - - - Putative adhesin
GDMGHCMF_01241 4.33e-13 - - - S - - - Protein of unknown function (DUF1700)
GDMGHCMF_01242 5.71e-17 - - - K ko:K10947 - ko00000,ko03000 negative regulation of transcription, DNA-templated
GDMGHCMF_01243 5.15e-101 XK27_06885 - - L - - - hydrolase
GDMGHCMF_01244 2.8e-35 - - - L ko:K07497 - ko00000 Integrase core domain protein
GDMGHCMF_01245 7.12e-44 - - - L ko:K07497 - ko00000 transposition
GDMGHCMF_01246 2.69e-35 - - - L - - - Transposase
GDMGHCMF_01247 3.12e-70 XK27_08085 - - - - - - -
GDMGHCMF_01248 1e-66 XK27_08080 - - G - - - Exopolysaccharide biosynthesis protein
GDMGHCMF_01249 1.05e-17 XK27_08080 - - G - - - Exopolysaccharide biosynthesis protein
GDMGHCMF_01250 9.41e-179 hisJ 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Histidinol phosphatase and related hydrolases of the PHP family
GDMGHCMF_01251 1.11e-154 - - - S - - - tigr01906
GDMGHCMF_01252 1.56e-180 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
GDMGHCMF_01253 3.99e-178 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
GDMGHCMF_01254 1.33e-276 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
GDMGHCMF_01258 1.57e-262 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
GDMGHCMF_01259 8.22e-144 rmlC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
GDMGHCMF_01260 2.62e-204 rfbA 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GDMGHCMF_01261 6.9e-261 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 oxidoreductase
GDMGHCMF_01262 4.34e-129 zupT - - P ko:K07238 - ko00000,ko02000 Mediates zinc uptake. May also transport other divalent cations
GDMGHCMF_01263 3.79e-28 zupT - - P ko:K07238 - ko00000,ko02000 Mediates zinc uptake. May also transport other divalent cations
GDMGHCMF_01264 1.34e-188 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GDMGHCMF_01265 2.59e-160 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
GDMGHCMF_01266 2.02e-92 mesH - - S - - - GtrA-like protein
GDMGHCMF_01267 1.85e-316 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GDMGHCMF_01268 6.39e-212 ybbR - - S - - - Protein conserved in bacteria
GDMGHCMF_01269 1.74e-155 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GDMGHCMF_01270 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Mur ligase, middle domain protein
GDMGHCMF_01271 5.93e-192 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
GDMGHCMF_01272 0.0 mprF 2.3.2.3 - J ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GDMGHCMF_01273 6.11e-169 - 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Alpha beta hydrolase
GDMGHCMF_01275 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 abc transporter atp-binding protein
GDMGHCMF_01276 2.24e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
GDMGHCMF_01277 1.3e-242 yfmL - - L - - - DEAD DEAH box helicase
GDMGHCMF_01278 1.05e-32 - 6.3.2.2, 6.3.2.4 - F ko:K01919,ko:K01921 ko00270,ko00473,ko00480,ko00550,ko01100,ko01502,map00270,map00473,map00480,map00550,map01100,map01502 ko00000,ko00001,ko00002,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
GDMGHCMF_01279 1.43e-136 XK27_05680 - - M - - - carbamoylphosphate synthase large subunit
GDMGHCMF_01280 3.36e-64 XK27_05680 - - M - - - carbamoylphosphate synthase large subunit
GDMGHCMF_01281 1.13e-10 XK27_05675 - - S - - - Esterase
GDMGHCMF_01282 9.57e-46 XK27_05675 - - S - - - Esterase
GDMGHCMF_01283 4.96e-41 XK27_05670 - - S ko:K07017 - ko00000 Putative esterase
GDMGHCMF_01284 1.15e-33 XK27_05670 - - S ko:K07017 - ko00000 Putative esterase
GDMGHCMF_01285 0.0 gapN 1.2.1.9 - C ko:K00131 ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
GDMGHCMF_01286 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GDMGHCMF_01287 3.73e-49 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein Hpr
GDMGHCMF_01288 7.22e-283 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 Isocitrate dehydrogenase
GDMGHCMF_01289 6.04e-271 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
GDMGHCMF_01290 0.0 acnA 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GDMGHCMF_01291 1.61e-44 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
GDMGHCMF_01292 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GDMGHCMF_01293 8.44e-237 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GDMGHCMF_01295 1.37e-74 - - - L - - - PFAM transposase IS116 IS110 IS902 family
GDMGHCMF_01296 8.56e-34 - - - L - - - Transposase (IS116 IS110 IS902 family)
GDMGHCMF_01297 2.11e-206 ypuA - - S - - - secreted protein
GDMGHCMF_01298 3.79e-92 ywkD - - E ko:K08234 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
GDMGHCMF_01299 5.6e-172 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase (surface protein transpeptidase)
GDMGHCMF_01300 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GDMGHCMF_01301 3.98e-230 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
GDMGHCMF_01302 0.0 noxE - - P - - - NADH oxidase
GDMGHCMF_01303 0.0 yheS_1 - - S - - - abc transporter atp-binding protein
GDMGHCMF_01304 2.97e-102 - - - S - - - ECF-type riboflavin transporter, S component
GDMGHCMF_01305 1.6e-175 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Belongs to the pyridoxine kinase family
GDMGHCMF_01306 8.12e-110 - - - S - - - ECF-type riboflavin transporter, S component
GDMGHCMF_01309 2.44e-303 ycxD - - K - - - Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
GDMGHCMF_01310 5.37e-74 nrdD_1 1.1.98.6, 1.17.4.1 - F ko:K00525,ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Ribonucleoside-triphosphate reductase
GDMGHCMF_01311 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GDMGHCMF_01312 1.46e-118 XK27_03150 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GDMGHCMF_01313 1.68e-248 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GDMGHCMF_01314 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
GDMGHCMF_01315 3.07e-159 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
GDMGHCMF_01316 2.11e-221 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GDMGHCMF_01317 7.13e-255 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GDMGHCMF_01318 9.59e-103 alkD - - L - - - Dna alkylation repair
GDMGHCMF_01319 4.37e-119 pat 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 acetyltransferase
GDMGHCMF_01320 3.8e-16 - - - - - - - -
GDMGHCMF_01321 2.08e-67 - - - - - - - -
GDMGHCMF_01322 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GDMGHCMF_01323 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
GDMGHCMF_01324 9.21e-49 yfnB 3.8.1.2 - E ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 hydrolase
GDMGHCMF_01325 6.68e-28 yfnB 3.8.1.2 - E ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 hydrolase
GDMGHCMF_01326 1.16e-155 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
GDMGHCMF_01327 1.06e-38 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
GDMGHCMF_01328 2.3e-130 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
GDMGHCMF_01329 3.63e-51 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
GDMGHCMF_01330 1.95e-106 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
GDMGHCMF_01331 2.01e-127 - - - S ko:K01992 - ko00000,ko00002,ko02000 transport system, permease component
GDMGHCMF_01332 3.85e-130 desR - - K ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GDMGHCMF_01333 4.36e-243 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GDMGHCMF_01334 4.12e-170 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
GDMGHCMF_01335 1.98e-201 XK27_09825 - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
GDMGHCMF_01338 6.16e-210 yocS - - S ko:K03453 - ko00000 Transporter
GDMGHCMF_01339 5.76e-107 - - - F - - - cytidine deaminase activity
GDMGHCMF_01340 3.22e-46 XK27_05000 - - S ko:K06940 - ko00000 metal cluster binding
GDMGHCMF_01341 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
GDMGHCMF_01342 7.36e-172 yxdL - - V ko:K02003,ko:K19083 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
GDMGHCMF_01343 3.9e-219 - - - T - - - Histidine kinase
GDMGHCMF_01344 7.44e-159 graR - - KT ko:K19082 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GDMGHCMF_01345 7.08e-100 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
GDMGHCMF_01346 7.94e-167 pbuX - - F ko:K16169 - ko00000,ko02000 xanthine permease
GDMGHCMF_01347 9.16e-57 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
GDMGHCMF_01348 1.85e-316 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
GDMGHCMF_01349 5.29e-237 msrA 1.8.4.11, 1.8.4.12 - O ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GDMGHCMF_01350 3.13e-117 yxeM - - ET ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
GDMGHCMF_01351 7.71e-250 - 4.3.2.2, 5.5.1.2 - F ko:K01756,ko:K01857 ko00230,ko00250,ko00362,ko01100,ko01110,ko01120,ko01130,ko01220,map00230,map00250,map00362,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko00002,ko01000 Adenylosuccinate lyase
GDMGHCMF_01352 5.37e-118 yxeO - - E ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
GDMGHCMF_01353 5.12e-93 yxeN - - U ko:K02029,ko:K16959,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, permease protein
GDMGHCMF_01354 1.13e-74 - - - K - - - Acetyltransferase (GNAT) domain
GDMGHCMF_01355 3.99e-141 - - - S - - - MmgE/PrpD family
GDMGHCMF_01356 6.99e-186 ykrV3 - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 mutations do not affect methionine salvage in vivo however
GDMGHCMF_01357 8.58e-130 - - - C ko:K08317 - ko00000,ko01000 glycerol dehydrogenase
GDMGHCMF_01359 3.98e-231 hipO2 - - E ko:K01436,ko:K21613 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
GDMGHCMF_01360 1.64e-298 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
GDMGHCMF_01361 3.2e-46 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
GDMGHCMF_01362 1.35e-34 csbD - - K - - - CsbD-like
GDMGHCMF_01363 2.67e-09 - - - S - - - Carbohydrate-binding domain-containing protein Cthe_2159
GDMGHCMF_01364 4.6e-294 yfnA - - E ko:K03294 - ko00000 amino acid
GDMGHCMF_01365 9.54e-140 XK27_02070 - - S ko:K07078 - ko00000 nitroreductase
GDMGHCMF_01366 9.05e-25 catE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
GDMGHCMF_01367 3.46e-39 catE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
GDMGHCMF_01368 8.04e-93 catE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
GDMGHCMF_01369 2.44e-99 ywnA_2 - - K - - - Transcriptional regulator
GDMGHCMF_01370 8.05e-198 - - - E - - - Alpha/beta hydrolase of unknown function (DUF915)
GDMGHCMF_01371 6.61e-86 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GDMGHCMF_01372 2.76e-178 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GDMGHCMF_01373 8.21e-143 ydgI - - C - - - Nitroreductase
GDMGHCMF_01374 8.4e-124 - - - S - - - Protein of unknown function (DUF1275)
GDMGHCMF_01375 2.26e-05 - - - S - - - Protein of unknown function (DUF1275)
GDMGHCMF_01376 1.07e-203 yvgN - - C - - - reductase
GDMGHCMF_01377 1.7e-225 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
GDMGHCMF_01378 0.0 XK27_07020 - - S - - - Belongs to the UPF0371 family
GDMGHCMF_01380 2.62e-49 BP1961 - - P - - - nitric oxide dioxygenase activity
GDMGHCMF_01381 4.18e-69 saeR - - K ko:K10682 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
GDMGHCMF_01382 1.27e-84 - - - S - - - Signal peptide protein, YSIRK family
GDMGHCMF_01384 1.44e-79 - - - - - - - -
GDMGHCMF_01385 0.0 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GDMGHCMF_01386 4.31e-188 - - - - - - - -
GDMGHCMF_01389 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
GDMGHCMF_01390 5.63e-111 hsdS 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain protein
GDMGHCMF_01391 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 Type I restriction-modification system
GDMGHCMF_01392 0.0 - - - M - - - family 8
GDMGHCMF_01393 3.08e-52 - - - L ko:K07483 - ko00000 transposase activity
GDMGHCMF_01394 6.25e-172 - - - L - - - Transposase and inactivated derivatives
GDMGHCMF_01395 5.64e-23 - - - - - - - -
GDMGHCMF_01396 1.31e-195 - - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MatE
GDMGHCMF_01397 2.93e-10 - - - S - - - Coenzyme PQQ synthesis protein D (PqqD)
GDMGHCMF_01398 2.33e-136 - - - C ko:K22227 - ko00000 Fe-S oxidoreductases
GDMGHCMF_01399 6.25e-227 - - - EGP - - - Major Facilitator Superfamily
GDMGHCMF_01400 0.0 - - - I - - - radical SAM domain protein
GDMGHCMF_01402 7.24e-205 - - - K - - - Transcriptional activator, Rgg GadR MutR family
GDMGHCMF_01403 1.88e-194 - - - L ko:K07497 - ko00000 Integrase core domain protein
GDMGHCMF_01404 8.81e-114 - - - L ko:K07483 - ko00000 transposase activity
GDMGHCMF_01406 2.36e-110 - - - - - - - -
GDMGHCMF_01407 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 ATPase involved in DNA repair
GDMGHCMF_01408 1.47e-289 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
GDMGHCMF_01409 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 -beta-galactosidase
GDMGHCMF_01410 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 transporter
GDMGHCMF_01411 2.47e-250 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
GDMGHCMF_01412 3.35e-245 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
GDMGHCMF_01413 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDPglucose--hexose-1-phosphate uridylyltransferase
GDMGHCMF_01414 1.38e-274 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GDMGHCMF_01415 4.01e-236 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
GDMGHCMF_01416 1.7e-13 - - - L ko:K07497 - ko00000 Integrase core domain protein
GDMGHCMF_01417 1.49e-279 zmpB - - M ko:K08643 - ko00000,ko01000,ko01002 M26 IgA1-specific Metallo-endopeptidase C-terminal region
GDMGHCMF_01418 7.29e-23 zmpB - - M ko:K08643 - ko00000,ko01000,ko01002 M26 IgA1-specific Metallo-endopeptidase C-terminal region
GDMGHCMF_01419 0.0 ndvA - - V ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
GDMGHCMF_01420 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 abc transporter atp-binding protein
GDMGHCMF_01421 0.0 gshF 6.3.2.2 - H ko:K01919,ko:K16786,ko:K16787 ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the glutamate--cysteine ligase type 1 family
GDMGHCMF_01422 1.19e-102 - - - L - - - Transposase
GDMGHCMF_01423 5.38e-67 - - - L - - - Transposase
GDMGHCMF_01424 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
GDMGHCMF_01425 4.53e-238 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
GDMGHCMF_01426 1.5e-169 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
GDMGHCMF_01427 6.44e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GDMGHCMF_01430 2.7e-146 vraR - - K ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GDMGHCMF_01431 2.65e-223 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GDMGHCMF_01432 2.55e-153 yvqF - - KT ko:K11622 ko02020,map02020 ko00000,ko00001 membrane
GDMGHCMF_01433 5.07e-299 - - - L ko:K07485 - ko00000 Transposase
GDMGHCMF_01434 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
GDMGHCMF_01435 1.88e-166 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
GDMGHCMF_01436 2.37e-309 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GDMGHCMF_01437 1.73e-220 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GDMGHCMF_01438 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GDMGHCMF_01439 5.37e-59 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-directed 5'-3' RNA polymerase activity
GDMGHCMF_01440 2.93e-143 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
GDMGHCMF_01441 1.22e-306 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GDMGHCMF_01442 5.2e-186 XK27_02985 - - S - - - overlaps another CDS with the same product name
GDMGHCMF_01443 3.54e-185 - - - S - - - overlaps another CDS with the same product name
GDMGHCMF_01444 3.45e-83 ytrA - - K ko:K07979 - ko00000,ko03000 Transcriptional
GDMGHCMF_01445 3.38e-158 skfE - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
GDMGHCMF_01446 4.91e-170 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPase activity
GDMGHCMF_01447 3.46e-218 amiF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GDMGHCMF_01448 8.41e-260 amiE - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GDMGHCMF_01449 2.73e-211 amiD - - P ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
GDMGHCMF_01450 0.0 amiC - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
GDMGHCMF_01451 0.0 amiA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
GDMGHCMF_01452 1.87e-29 amiF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GDMGHCMF_01453 1.41e-46 tatD - - L ko:K03424 - ko00000,ko01000 Hydrolase, tatd
GDMGHCMF_01454 7.68e-274 oxlT - - P ko:K08177 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
GDMGHCMF_01455 1.08e-52 - - - L ko:K07483 - ko00000 transposase activity
GDMGHCMF_01456 2.51e-32 - - - L ko:K07483 - ko00000 transposase activity
GDMGHCMF_01457 2.48e-228 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
GDMGHCMF_01458 1.27e-220 yjbO 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
GDMGHCMF_01459 1.29e-194 nadK 2.7.1.23 - H ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GDMGHCMF_01460 6.06e-150 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 Gtp pyrophosphokinase
GDMGHCMF_01461 1.11e-133 yjbK - - S - - - Adenylate cyclase
GDMGHCMF_01462 1.43e-225 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GDMGHCMF_01463 2.52e-261 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
GDMGHCMF_01464 1.2e-76 XK27_04120 - - S - - - Putative amino acid metabolism
GDMGHCMF_01465 2.51e-152 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GDMGHCMF_01466 5.64e-161 - - - T ko:K07010 - ko00000,ko01002 peptidase C26
GDMGHCMF_01467 5.17e-151 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
GDMGHCMF_01468 0.0 rgpF - - M ko:K07272 - ko00000,ko01000,ko01003,ko01005 Rhamnan synthesis protein F
GDMGHCMF_01469 5.09e-283 rgpD 3.6.3.40 - P ko:K01990,ko:K09691,ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
GDMGHCMF_01470 2.56e-180 - - - GM ko:K01992,ko:K09690,ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
GDMGHCMF_01471 8.9e-219 rgpB - GT2 M ko:K12997 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
GDMGHCMF_01472 1.28e-276 rgpA - GT4 M ko:K12996 - ko00000,ko01000,ko01003,ko01005 Domain of unknown function (DUF1972)
GDMGHCMF_01473 0.0 - - - S - - - Glucosyl transferase GtrII
GDMGHCMF_01474 2.6e-279 - - GT4 M ko:K00754 - ko00000,ko01000 transferase activity, transferring glycosyl groups
GDMGHCMF_01475 3.02e-276 - - - M - - - Psort location CytoplasmicMembrane, score
GDMGHCMF_01476 0.0 - - - M - - - Glycosyltransferase like family 2
GDMGHCMF_01477 1.5e-22 - - - S - - - Psort location CytoplasmicMembrane, score
GDMGHCMF_01478 1.31e-43 - - - S - - - Psort location CytoplasmicMembrane, score
GDMGHCMF_01479 3.32e-196 - - - S - - - Glycosyltransferase group 2 family protein
GDMGHCMF_01480 8e-57 - - - S ko:K09153 - ko00000 Uncharacterized conserved protein (DUF2304)
GDMGHCMF_01481 3.14e-166 arnC - - M ko:K00786 - ko00000,ko01000 group 2 family protein
GDMGHCMF_01482 9.46e-235 - - - S - - - Glycosyltransferase like family 2
GDMGHCMF_01483 3.57e-236 - - - S - - - Glycosyltransferase like family 2
GDMGHCMF_01484 7.97e-275 - - - S - - - membrane protein involved in the export of O-antigen and teichoic acid
GDMGHCMF_01485 7.75e-207 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
GDMGHCMF_01486 1.83e-296 - - - S - - - Predicted membrane protein (DUF2142)
GDMGHCMF_01487 1.72e-214 yfdH - GT2 M ko:K12999,ko:K20534 - ko00000,ko01000,ko01003,ko01005,ko02000 COG0463, glycosyltransferases involved in cell wall biogenesis
GDMGHCMF_01488 1.98e-73 yitW - - K - - - metal-sulfur cluster biosynthetic enzyme
GDMGHCMF_01489 3.39e-254 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
GDMGHCMF_01490 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
GDMGHCMF_01491 1.14e-62 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
GDMGHCMF_01492 2.89e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
GDMGHCMF_01493 9.58e-174 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
GDMGHCMF_01494 1.85e-265 arcT - - E - - - Aminotransferase
GDMGHCMF_01495 2.54e-174 XK27_04395 - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter
GDMGHCMF_01496 1.9e-178 XK27_04395 - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
GDMGHCMF_01497 2.15e-109 XK27_04400 3.6.1.55 - F ko:K03574,ko:K12944 - ko00000,ko01000,ko03400 Nudix family
GDMGHCMF_01498 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
GDMGHCMF_01500 6.83e-90 - - - S ko:K07052 - ko00000 CAAX amino terminal protease family protein
GDMGHCMF_01501 1.8e-26 - - - S ko:K07052 - ko00000 CAAX amino terminal protease family protein
GDMGHCMF_01502 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type amino acid transport signal transduction systems periplasmic component domain
GDMGHCMF_01503 2.68e-171 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 abc transporter atp-binding protein
GDMGHCMF_01504 1.84e-24 XK27_00735 - - - - - - -
GDMGHCMF_01505 1.5e-312 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GDMGHCMF_01506 1.4e-09 - - - S - - - Protein of unknown function (DUF4044)
GDMGHCMF_01507 1.75e-170 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
GDMGHCMF_01510 2.04e-39 - - - Q ko:K02614 ko00360,map00360 ko00000,ko00001,ko01000 protein possibly involved in aromatic compounds catabolism
GDMGHCMF_01511 4.35e-17 - - - Q ko:K02614 ko00360,map00360 ko00000,ko00001,ko01000 protein possibly involved in aromatic compounds catabolism
GDMGHCMF_01512 2.07e-135 - - - EG - - - Permeases of the drug metabolite transporter (DMT) superfamily
GDMGHCMF_01514 5.64e-144 serB 3.1.3.3 - E ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01009 phosphoserine phosphatase
GDMGHCMF_01515 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GDMGHCMF_01516 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GDMGHCMF_01517 1.07e-141 - - - S - - - IA, variant 1
GDMGHCMF_01518 1.31e-150 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 effector of murein hydrolase
GDMGHCMF_01519 6.45e-74 lrgA - - S ko:K06518 - ko00000,ko02000 Effector of murein hydrolase LrgA
GDMGHCMF_01521 7.18e-79 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
GDMGHCMF_01522 1.96e-49 ogt 2.1.1.63, 3.2.2.20 - L ko:K00567,ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 methylated-DNA-[protein]-cysteine S-methyltransferase activity
GDMGHCMF_01523 1.39e-276 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GDMGHCMF_01524 5.63e-136 - - - M - - - Acetyltransferase (GNAT) domain
GDMGHCMF_01525 3.61e-267 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GDMGHCMF_01526 2.99e-59 - - - GK - - - ROK family
GDMGHCMF_01527 1.15e-92 - - - GK - - - ROK family
GDMGHCMF_01528 1.37e-92 gloA 4.4.1.5 - E ko:K01759,ko:K15772 ko00620,ko02010,map00620,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Lactoylglutathione lyase
GDMGHCMF_01529 1.37e-195 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 HflC and HflK could regulate a protease
GDMGHCMF_01530 3.44e-263 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 spermidine putrescine ABC transporter
GDMGHCMF_01531 5.13e-171 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type spermidine putrescine transport system, permease component II
GDMGHCMF_01532 3.31e-178 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type spermidine putrescine transport system, permease component I
GDMGHCMF_01533 1.95e-272 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
GDMGHCMF_01534 6.74e-218 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
GDMGHCMF_01535 7.94e-114 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GDMGHCMF_01536 1.49e-81 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GDMGHCMF_01537 0.0 amy 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
GDMGHCMF_01538 5.24e-188 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GDMGHCMF_01539 1.17e-129 folE 3.5.4.16 - F ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 gtp cyclohydrolase
GDMGHCMF_01540 0.0 ydaO - - E - - - amino acid
GDMGHCMF_01541 5.53e-304 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
GDMGHCMF_01542 9.09e-50 ylqC - - L ko:K06960 - ko00000 Belongs to the UPF0109 family
GDMGHCMF_01543 1.87e-57 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
GDMGHCMF_01544 1.09e-218 tehB 2.1.1.265 - PQ ko:K16868 - ko00000,ko01000 tellurite resistance protein tehb
GDMGHCMF_01546 6.69e-200 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
GDMGHCMF_01547 1.22e-97 - - - S - - - QueT transporter
GDMGHCMF_01548 1.58e-153 - - - L - - - Transposase DDE domain
GDMGHCMF_01549 1.83e-235 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
GDMGHCMF_01550 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GDMGHCMF_01551 2.79e-111 ccl - - S - - - cog cog4708
GDMGHCMF_01552 2.25e-203 rbn - - E ko:K07058 - ko00000 Belongs to the UPF0761 family
GDMGHCMF_01553 2.86e-211 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
GDMGHCMF_01554 2.9e-293 ytoI - - K - - - transcriptional regulator containing CBS domains
GDMGHCMF_01555 8.94e-47 XK27_07830 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase GNAT Family
GDMGHCMF_01556 5.47e-60 XK27_07830 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase GNAT Family
GDMGHCMF_01557 4.79e-292 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GDMGHCMF_01558 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
GDMGHCMF_01559 2.38e-137 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
GDMGHCMF_01560 2.06e-182 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
GDMGHCMF_01561 4.6e-196 nodB3 - - G - - - deacetylase
GDMGHCMF_01562 4.82e-178 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase
GDMGHCMF_01563 6.85e-55 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
GDMGHCMF_01564 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
GDMGHCMF_01565 4.95e-195 corA - - P - - - CorA-like protein
GDMGHCMF_01566 1.07e-82 yjqA - - S - - - Bacterial PH domain
GDMGHCMF_01567 2.96e-125 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter
GDMGHCMF_01568 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GDMGHCMF_01569 2.88e-33 ywaF - - S - - - Integral membrane protein (intg_mem_TP0381)
GDMGHCMF_01570 2.6e-96 ywaF - - S - - - Integral membrane protein (intg_mem_TP0381)
GDMGHCMF_01571 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
GDMGHCMF_01573 7.77e-199 cjaA - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
GDMGHCMF_01574 3.33e-173 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 abc transporter atp-binding protein
GDMGHCMF_01575 1.4e-148 glnP7 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter (Permease
GDMGHCMF_01576 4.76e-146 glnP9 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter (Permease
GDMGHCMF_01577 6.23e-244 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
GDMGHCMF_01578 1.91e-42 copZ - - P - - - Heavy metal-associated domain protein
GDMGHCMF_01579 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
GDMGHCMF_01580 4.81e-94 copY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor, CopY TcrY family
GDMGHCMF_01581 1.68e-181 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
GDMGHCMF_01582 1e-290 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
GDMGHCMF_01583 2.17e-128 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the TrpF family
GDMGHCMF_01584 7.62e-171 trpC 4.1.1.48 - E ko:K01609 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
GDMGHCMF_01585 2.69e-231 trpD 2.4.2.18, 4.1.3.27 - F ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GDMGHCMF_01586 1.01e-135 trpG 4.1.3.27 - EH ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 anthranilate
GDMGHCMF_01587 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GDMGHCMF_01588 3.87e-56 MA20_20425 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 - E ko:K00800,ko:K03785,ko:K04092,ko:K04782 ko00400,ko01053,ko01100,ko01110,ko01130,ko01230,map00400,map01053,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Chorismate mutase
GDMGHCMF_01589 0.0 ctpE - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
GDMGHCMF_01590 5.31e-59 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GDMGHCMF_01591 2.01e-51 - - - L - - - transposase activity
GDMGHCMF_01592 3.42e-157 - - - K - - - transcriptional regulator, MerR family
GDMGHCMF_01593 1.26e-133 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
GDMGHCMF_01594 2e-73 WQ51_02910 - - S - - - Protein of unknown function, DUF536
GDMGHCMF_01595 1.05e-83 XK27_02560 - - S - - - cog cog2151
GDMGHCMF_01596 0.0 ilvD 4.2.1.9 - E ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the IlvD Edd family
GDMGHCMF_01597 9.59e-289 ytfP - - S ko:K07007 - ko00000 Flavoprotein
GDMGHCMF_01599 1.46e-154 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
GDMGHCMF_01600 8.46e-197 ytmP - - M - - - Phosphotransferase
GDMGHCMF_01601 8.59e-229 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
GDMGHCMF_01602 2.04e-169 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
GDMGHCMF_01603 2.51e-94 hit - - FG ko:K02503 - ko00000,ko04147 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
GDMGHCMF_01604 1.37e-14 - - - - - - - -
GDMGHCMF_01605 5.45e-67 - - - S - - - CD20-like family
GDMGHCMF_01606 1.01e-77 - - - - - - - -
GDMGHCMF_01609 0.0 clpL - - O ko:K04086 - ko00000,ko03110 ATP-dependent Clp protease ATP-binding subunit
GDMGHCMF_01610 2.89e-252 ylbM - - S - - - Belongs to the UPF0348 family
GDMGHCMF_01611 2.87e-176 XK27_06665 - - Q - - - Methyltransferase domain protein
GDMGHCMF_01612 4e-76 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
GDMGHCMF_01613 1.59e-136 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
GDMGHCMF_01614 9.14e-152 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GDMGHCMF_01615 3.22e-65 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
GDMGHCMF_01616 2.78e-275 yqeH - - S ko:K06948 - ko00000,ko03009 in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
GDMGHCMF_01617 6.17e-126 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
GDMGHCMF_01618 1.02e-185 - - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
GDMGHCMF_01619 5.26e-42 - - - - - - - -
GDMGHCMF_01620 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GDMGHCMF_01621 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
GDMGHCMF_01622 7.49e-64 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GDMGHCMF_01623 5.59e-33 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 transferase activity, transferring glycosyl groups
GDMGHCMF_01624 6.18e-63 ascB 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
GDMGHCMF_01625 1.28e-28 ascB 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
GDMGHCMF_01626 4.82e-126 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GDMGHCMF_01627 1.9e-196 metQ - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
GDMGHCMF_01628 2.48e-125 pncA - - Q ko:K16788 - ko00000,ko02000 isochorismatase
GDMGHCMF_01629 6.8e-177 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GDMGHCMF_01630 5.06e-301 aspC 2.6.1.2, 2.6.1.66 - E ko:K14260 ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
GDMGHCMF_01631 7.54e-99 XK27_03180 - - T - - - universal stress protein
GDMGHCMF_01633 5.69e-192 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GDMGHCMF_01635 3.73e-300 hlyX - - S ko:K03699 - ko00000,ko02042 COG1253 Hemolysins and related proteins containing CBS domains
GDMGHCMF_01636 1.01e-182 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
GDMGHCMF_01637 0.0 nhaP1 - - P ko:K03316 - ko00000 NhaP-type Na H and K H antiporters
GDMGHCMF_01639 9e-127 mraW1 - - J - - - (SAM)-dependent
GDMGHCMF_01640 1.77e-235 ytqA - - S ko:K07139 - ko00000 radical SAM protein
GDMGHCMF_01641 3.47e-55 - - - - - - - -
GDMGHCMF_01642 6.3e-208 - - - L ko:K07485 - ko00000 Transposase
GDMGHCMF_01643 2.45e-246 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
GDMGHCMF_01644 5.14e-111 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GDMGHCMF_01645 1.23e-118 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
GDMGHCMF_01646 2.09e-214 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
GDMGHCMF_01647 5.53e-11 - - - S - - - Protein of unknown function (DUF4059)
GDMGHCMF_01648 5.38e-167 tcyN 3.6.3.21 - E ko:K02028,ko:K10010,ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
GDMGHCMF_01649 3.84e-206 yxeN - - P ko:K02029,ko:K16959,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
GDMGHCMF_01650 1.42e-192 - - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC-type amino acid transport signal transduction systems, periplasmic component domain
GDMGHCMF_01653 5.02e-255 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GDMGHCMF_01654 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 formate acetyltransferase'
GDMGHCMF_01655 6.54e-96 - - - L ko:K07483 - ko00000 transposase IS3 IS911 family protein
GDMGHCMF_01656 3.98e-83 cah 4.2.1.1 - P ko:K01674 ko00910,map00910 ko00000,ko00001,ko01000 carbonic anhydrase
GDMGHCMF_01657 1.07e-51 cah 4.2.1.1 - P ko:K01674 ko00910,map00910 ko00000,ko00001,ko01000 carbonate dehydratase activity
GDMGHCMF_01658 1.55e-110 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GDMGHCMF_01659 2.77e-65 hsdS_1 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain
GDMGHCMF_01660 7.75e-44 - - - D - - - nuclear chromosome segregation
GDMGHCMF_01661 1.08e-41 - - - L ko:K04763 - ko00000,ko03036 DNA integration
GDMGHCMF_01662 5.55e-74 - - - L - - - Phage integrase family
GDMGHCMF_01663 4.43e-125 XK27_05540 - - S - - - Gram-negative-bacterium-type cell wall biogenesis
GDMGHCMF_01664 3.33e-163 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
GDMGHCMF_01665 1.14e-148 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
GDMGHCMF_01666 3.36e-43 - - - - - - - -
GDMGHCMF_01667 4.83e-234 - - - V - - - COG1680 Beta-lactamase class C and other penicillin binding proteins
GDMGHCMF_01668 1.3e-71 cppA - - E - - - CppA N-terminal
GDMGHCMF_01669 2.52e-95 cppA - - E - - - CppA N-terminal
GDMGHCMF_01670 7.59e-212 gla - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
GDMGHCMF_01671 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
GDMGHCMF_01674 1.31e-63 spiA - - K ko:K18831 - ko00000,ko02048,ko03000 sequence-specific DNA binding
GDMGHCMF_01675 7.5e-31 blpT - - - - - - -
GDMGHCMF_01676 1.96e-63 blpT - - - - - - -
GDMGHCMF_01677 1.07e-67 blpT - - - - - - -
GDMGHCMF_01678 3.22e-156 - - - L - - - Transposase
GDMGHCMF_01679 2.97e-210 - - - L ko:K07497 - ko00000 integrase core domain
GDMGHCMF_01683 0.000313 - - - - - - - -
GDMGHCMF_01684 1.08e-34 - - - S - - - Bacteriocin class II with double-glycine leader peptide
GDMGHCMF_01687 4.47e-174 agrA - - KT ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 phosphorelay signal transduction system
GDMGHCMF_01688 2.44e-302 blpH 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
GDMGHCMF_01690 1.44e-310 mesE - - M ko:K20345 ko02024,map02024 ko00000,ko00001,ko02000 Transport protein ComB
GDMGHCMF_01691 0.0 comA - - V ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
GDMGHCMF_01692 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
GDMGHCMF_01693 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
GDMGHCMF_01695 2.82e-122 XK27_09885 - - V - - - Glycopeptide antibiotics resistance protein
GDMGHCMF_01696 2.62e-284 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
GDMGHCMF_01697 1.83e-134 yutD - - J - - - protein conserved in bacteria
GDMGHCMF_01698 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
GDMGHCMF_01700 1.12e-303 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
GDMGHCMF_01701 2.22e-233 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GDMGHCMF_01702 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 penicillin-binding protein
GDMGHCMF_01703 1.59e-61 ftsL - - D - - - cell division protein FtsL
GDMGHCMF_01704 3.33e-244 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
GDMGHCMF_01705 6.56e-84 - - - - - - - -
GDMGHCMF_01706 2.52e-34 - - - - - - - -
GDMGHCMF_01707 3.81e-55 - - - - - - - -
GDMGHCMF_01709 3.19e-42 - - - J - - - Protein of unknown function (DUF805)
GDMGHCMF_01710 2.1e-18 - - - D - - - nuclear chromosome segregation
GDMGHCMF_01711 4.97e-289 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GDMGHCMF_01712 1.31e-177 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GDMGHCMF_01713 0.0 XK27_00765 - - - ko:K01992 - ko00000,ko00002,ko02000 -
GDMGHCMF_01714 1.68e-168 ecsA_2 - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
GDMGHCMF_01715 5.54e-142 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
GDMGHCMF_01716 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
GDMGHCMF_01717 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
GDMGHCMF_01718 1.87e-119 - - - S - - - membrane
GDMGHCMF_01719 1.54e-08 XK27_02470 - - K - - - LytTr DNA-binding domain protein
GDMGHCMF_01720 4.05e-36 - - - KT - - - response to antibiotic
GDMGHCMF_01721 9.78e-37 - - - KT - - - response to antibiotic
GDMGHCMF_01722 1.08e-20 - - - KT - - - response to antibiotic
GDMGHCMF_01723 1.12e-83 yebC - - M - - - Membrane
GDMGHCMF_01724 3.35e-25 yebC - - M - - - Membrane
GDMGHCMF_01725 1.77e-21 yebC - - M - - - Membrane
GDMGHCMF_01726 0.0 - - - S - - - hydrolases of the HAD superfamily
GDMGHCMF_01727 5.23e-219 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
GDMGHCMF_01728 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GDMGHCMF_01729 8.15e-245 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GDMGHCMF_01730 1.23e-80 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
GDMGHCMF_01731 1.01e-251 aroG 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GDMGHCMF_01732 2.77e-249 aroH 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GDMGHCMF_01733 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
GDMGHCMF_01735 1.78e-240 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
GDMGHCMF_01736 4.6e-218 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 Fructokinase
GDMGHCMF_01737 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
GDMGHCMF_01738 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
GDMGHCMF_01739 4.28e-226 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional
GDMGHCMF_01740 2.67e-96 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GDMGHCMF_01741 9.01e-81 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 protein conserved in bacteria
GDMGHCMF_01742 6.05e-127 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GDMGHCMF_01743 1.43e-109 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
GDMGHCMF_01744 1.19e-255 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Belongs to the peptidase M24B family
GDMGHCMF_01747 2.31e-66 - - - V ko:K01990,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 'abc transporter, ATP-binding protein
GDMGHCMF_01748 1.51e-56 - - - V ko:K01990,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 'abc transporter, ATP-binding protein
GDMGHCMF_01753 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GDMGHCMF_01754 3.19e-213 corA - - P ko:K03284 - ko00000,ko02000 COG0598 Mg2 and Co2 transporters
GDMGHCMF_01755 2.81e-157 - - - S - - - Pfam PF06570
GDMGHCMF_01758 4.1e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GDMGHCMF_01759 1.7e-117 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
GDMGHCMF_01760 6.04e-60 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
GDMGHCMF_01761 1.52e-35 XK27_05745 - - - - - - -
GDMGHCMF_01762 2.08e-287 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific adenine glycosylase
GDMGHCMF_01769 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GDMGHCMF_01770 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
GDMGHCMF_01771 9.33e-119 cvpA - - S ko:K03558 - ko00000 toxin biosynthetic process
GDMGHCMF_01772 5.78e-19 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GDMGHCMF_01773 7.47e-203 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GDMGHCMF_01774 3.43e-141 spi 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
GDMGHCMF_01775 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
GDMGHCMF_01776 1.06e-60 azlD - - E - - - branched-chain amino acid
GDMGHCMF_01777 3.44e-146 XK27_12120 - - E - - - AzlC protein
GDMGHCMF_01778 6.68e-238 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GDMGHCMF_01779 2.18e-96 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
GDMGHCMF_01780 7.98e-155 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214, inactive homolog of metal-dependent proteases
GDMGHCMF_01781 6.45e-45 ykzG - - S - - - Belongs to the UPF0356 family
GDMGHCMF_01782 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GDMGHCMF_01784 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
GDMGHCMF_01785 2.63e-82 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 Transcriptional regulator
GDMGHCMF_01786 5.12e-112 - - - S - - - Fusaric acid resistance protein-like
GDMGHCMF_01787 4.14e-119 - - - L - - - Transposase
GDMGHCMF_01788 4.32e-279 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
GDMGHCMF_01789 1.03e-31 - - - L - - - Transposase
GDMGHCMF_01790 6.63e-28 - - - L - - - Transposase IS116 IS110 IS902
GDMGHCMF_01791 6.17e-86 - - - L - - - transposase IS116 IS110 IS902 family
GDMGHCMF_01792 1.08e-93 - - - L - - - COG3547 Transposase and inactivated derivatives
GDMGHCMF_01793 1.52e-238 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
GDMGHCMF_01794 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GDMGHCMF_01795 1.1e-103 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
GDMGHCMF_01796 1.24e-84 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GDMGHCMF_01797 6.02e-182 purR - - F ko:K09685 - ko00000,ko03000 operon repressor
GDMGHCMF_01798 9.98e-222 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 3'-5' exoribonuclease yhaM
GDMGHCMF_01799 5.13e-233 rmuC - - S ko:K09760 - ko00000 RmuC domain protein
GDMGHCMF_01800 2.24e-152 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
GDMGHCMF_01801 6.49e-152 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
GDMGHCMF_01802 1.2e-205 rsgA 3.1.3.100 - G ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
GDMGHCMF_01804 6.85e-196 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
GDMGHCMF_01805 5.18e-128 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GDMGHCMF_01806 6.12e-183 tatD - - L ko:K03424 - ko00000,ko01000 Hydrolase, tatd
GDMGHCMF_01807 2.91e-59 yneT - - S ko:K06929 - ko00000 CoA-binding protein
GDMGHCMF_01808 3.77e-68 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
GDMGHCMF_01809 2.09e-176 - - - S - - - Macro domain protein
GDMGHCMF_01811 2.33e-287 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
GDMGHCMF_01812 9.33e-20 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L34
GDMGHCMF_01813 0.0 - - - S - - - PFAM Uncharacterised protein family UPF0236
GDMGHCMF_01814 3.72e-95 - - - D - - - Filamentation induced by cAMP protein fic
GDMGHCMF_01815 2.65e-64 arsB - - P ko:K03325 - ko00000,ko02000 Sodium Bile acid symporter family
GDMGHCMF_01817 1.14e-114 - - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain protein
GDMGHCMF_01818 1.72e-291 - - - S - - - Psort location CytoplasmicMembrane, score
GDMGHCMF_01819 4.88e-06 - - - L ko:K07497 - ko00000 transposition
GDMGHCMF_01820 1.17e-112 tnpR - - L - - - Resolvase, N terminal domain
GDMGHCMF_01822 0.0 - - - U - - - relaxase
GDMGHCMF_01823 3.25e-32 - - - S - - - Bacterial mobilisation protein (MobC)
GDMGHCMF_01825 0.0 - - - L - - - Psort location Cytoplasmic, score
GDMGHCMF_01827 2.77e-182 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GDMGHCMF_01828 2.4e-199 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GDMGHCMF_01831 0.0 - - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 An automated process has identified a potential problem with this gene model
GDMGHCMF_01832 7.37e-57 - - - S - - - Protein of unknown function (DUF3801)
GDMGHCMF_01833 4.35e-69 - - - - - - - -
GDMGHCMF_01835 3.03e-83 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 single-stranded DNA binding
GDMGHCMF_01836 8.03e-128 - - - - - - - -
GDMGHCMF_01837 0.0 - - - M - - - CHAP domain protein
GDMGHCMF_01838 0.0 - - - U - - - Psort location Cytoplasmic, score
GDMGHCMF_01839 1.95e-56 - - - S - - - PrgI family protein
GDMGHCMF_01840 5.54e-127 - - - - - - - -
GDMGHCMF_01841 8.52e-25 - - - - - - - -
GDMGHCMF_01842 2.47e-26 - - - - - - - -
GDMGHCMF_01843 0.0 - - - D - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GDMGHCMF_01844 2.45e-51 - - - MU - - - outer membrane autotransporter barrel domain protein
GDMGHCMF_01845 1.71e-14 - - - - - - - -
GDMGHCMF_01847 8.34e-123 repA - - S - - - Replication initiator protein A
GDMGHCMF_01849 9.39e-235 jag - - S ko:K06346 - ko00000 RNA-binding protein
GDMGHCMF_01850 1.8e-180 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GDMGHCMF_01851 2.38e-72 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
GDMGHCMF_01852 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Argininosuccinate lyase
GDMGHCMF_01853 3.19e-294 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
GDMGHCMF_01854 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GDMGHCMF_01855 2.44e-82 amiA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 transmembrane transport
GDMGHCMF_01856 9.91e-35 amiA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 transmembrane transport
GDMGHCMF_01857 8.77e-99 amiA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
GDMGHCMF_01858 3.97e-39 amiA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
GDMGHCMF_01859 1.12e-154 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
GDMGHCMF_01860 5.65e-92 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GDMGHCMF_01861 5.44e-65 - - - S - - - Protein of unknown function (DUF3397)
GDMGHCMF_01862 1.12e-114 cah 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
GDMGHCMF_01863 3.47e-50 - - - S - - - Mitochondrial biogenesis AIM24
GDMGHCMF_01864 1.64e-47 - - - S - - - Mitochondrial biogenesis AIM24
GDMGHCMF_01865 3.92e-276 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GDMGHCMF_01866 9.97e-103 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
GDMGHCMF_01867 1.24e-26 XK27_09620 - - S - - - FMN reductase (NADPH) activity
GDMGHCMF_01868 3.67e-92 - - - S - - - reductase
GDMGHCMF_01869 2.79e-293 XK27_09615 - - C ko:K19784 - ko00000 reductase
GDMGHCMF_01870 5.49e-10 nirC_1 - - P - - - Formate nitrite transporter
GDMGHCMF_01871 8.95e-92 nirC_1 - - P - - - Formate nitrite transporter
GDMGHCMF_01872 1.12e-97 XK27_08585 - - S ko:K16926 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score
GDMGHCMF_01873 5.7e-234 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
GDMGHCMF_01874 1.64e-210 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
GDMGHCMF_01875 1.49e-148 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
GDMGHCMF_01876 3.29e-121 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GDMGHCMF_01877 3.29e-281 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
GDMGHCMF_01878 6.92e-105 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
GDMGHCMF_01879 4.79e-151 - - - S ko:K07025 - ko00000 HAD hydrolase, family IA, variant
GDMGHCMF_01880 4.71e-201 rrmA 2.1.1.187 - Q ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 methyltransferase
GDMGHCMF_01884 4.69e-115 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
GDMGHCMF_01885 3.13e-86 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
GDMGHCMF_01886 7.56e-48 yeeD - - O ko:K07112 - ko00000 sulfur carrier activity
GDMGHCMF_01887 3.47e-243 yeeE - - S ko:K07112 - ko00000 Sulphur transport
GDMGHCMF_01888 6.43e-146 XK27_10290 - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GDMGHCMF_01889 2.27e-69 ytpP - - CO - - - Thioredoxin
GDMGHCMF_01891 6.14e-259 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
GDMGHCMF_01892 2.75e-169 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GDMGHCMF_01893 3.23e-141 - - - S ko:K07052 - ko00000 CAAX amino terminal protease family protein
GDMGHCMF_01894 3.54e-35 lanR - - K ko:K07729 - ko00000,ko03000 sequence-specific DNA binding
GDMGHCMF_01895 4.27e-278 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GDMGHCMF_01896 1.88e-223 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
GDMGHCMF_01897 9.32e-17 - - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
GDMGHCMF_01898 1.54e-91 comGF - - U ko:K02248 - ko00000,ko00002,ko02044 Competence protein ComGF
GDMGHCMF_01899 2.58e-21 - - - NU - - - Type II secretory pathway pseudopilin
GDMGHCMF_01900 1.47e-75 cglD - - NU ko:K02246 - ko00000,ko00002,ko02044 Competence protein
GDMGHCMF_01901 2.61e-61 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
GDMGHCMF_01902 1.37e-190 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
GDMGHCMF_01903 2.26e-217 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GDMGHCMF_01904 2.56e-87 - - - S - - - cog cog4699
GDMGHCMF_01905 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GDMGHCMF_01906 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GDMGHCMF_01907 0.0 pbp1B 2.4.1.129 GT51 M ko:K03693,ko:K12551 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
GDMGHCMF_01908 3.38e-302 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GDMGHCMF_01909 2.67e-250 ilvC 1.1.1.86 - H ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GDMGHCMF_01910 3.94e-98 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
GDMGHCMF_01911 0.0 ilvB 2.2.1.6 - EH ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
GDMGHCMF_01912 1.23e-305 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
GDMGHCMF_01913 1.77e-54 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
GDMGHCMF_01914 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
GDMGHCMF_01915 1.87e-76 asp - - S - - - cog cog1302
GDMGHCMF_01916 3.75e-286 norN - - V - - - Mate efflux family protein
GDMGHCMF_01917 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
GDMGHCMF_01918 2.56e-64 adh 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
GDMGHCMF_01919 8.19e-41 adh 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
GDMGHCMF_01920 4.94e-62 adh 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
GDMGHCMF_01921 1.11e-27 adh 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
GDMGHCMF_01922 3.79e-83 - 1.1.1.1, 1.2.1.10, 1.2.1.87 - C ko:K04072,ko:K13922 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Dehydrogenase
GDMGHCMF_01923 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
GDMGHCMF_01924 1.59e-45 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
GDMGHCMF_01925 4.45e-78 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
GDMGHCMF_01926 4.84e-86 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
GDMGHCMF_01927 4.96e-72 treB 2.7.1.201 - G ko:K02817,ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS System
GDMGHCMF_01928 1.02e-145 treR - - K ko:K03486 - ko00000,ko03000 trehalose operon
GDMGHCMF_01929 2.27e-122 ywlG - - S - - - Belongs to the UPF0340 family
GDMGHCMF_01932 7.67e-26 - - - L ko:K07483 - ko00000 Transposase
GDMGHCMF_01933 2.93e-260 - - - L - - - DNA integration
GDMGHCMF_01934 1.16e-209 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 aldolase
GDMGHCMF_01936 4.01e-162 - - - H - - - gamma-glutamylcysteine synthetase
GDMGHCMF_01937 1.51e-48 - - - H - - - gamma-glutamylcysteine synthetase
GDMGHCMF_01938 3.26e-48 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
GDMGHCMF_01939 5.04e-82 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 ribosomal protein l17
GDMGHCMF_01940 2.1e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GDMGHCMF_01941 1.57e-80 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GDMGHCMF_01942 4.42e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GDMGHCMF_01943 3.26e-22 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
GDMGHCMF_01944 6.91e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GDMGHCMF_01945 3.41e-151 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
GDMGHCMF_01946 2.12e-293 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
GDMGHCMF_01947 1.03e-85 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
GDMGHCMF_01948 2e-32 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 ribosomal protein l30
GDMGHCMF_01949 9.94e-104 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GDMGHCMF_01950 7.15e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GDMGHCMF_01951 1.44e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GDMGHCMF_01952 3.78e-88 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GDMGHCMF_01953 4.64e-36 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GDMGHCMF_01954 5.86e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GDMGHCMF_01955 1.63e-63 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GDMGHCMF_01956 1.04e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GDMGHCMF_01957 3.08e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GDMGHCMF_01958 3.15e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
GDMGHCMF_01959 1.15e-89 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GDMGHCMF_01960 8.34e-147 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GDMGHCMF_01961 3.47e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GDMGHCMF_01962 8.13e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GDMGHCMF_01963 9.79e-194 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GDMGHCMF_01964 6e-60 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
GDMGHCMF_01965 2.13e-135 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
GDMGHCMF_01966 1.06e-140 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GDMGHCMF_01967 1.01e-62 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
GDMGHCMF_01968 4.89e-238 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
GDMGHCMF_01969 0.0 XK27_09800 - - I - - - Acyltransferase
GDMGHCMF_01970 2.43e-47 - - - S - - - MORN repeat protein
GDMGHCMF_01971 3.25e-106 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GDMGHCMF_01972 7.42e-314 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GDMGHCMF_01973 1.8e-64 flaR - - F - - - topology modulation protein
GDMGHCMF_01975 1.07e-302 rarA - - L ko:K07478 - ko00000 ATPase related to the helicase subunit of the Holliday junction resolvase
GDMGHCMF_01976 1e-35 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
GDMGHCMF_01977 4.83e-59 yrzL - - S - - - Belongs to the UPF0297 family
GDMGHCMF_01978 8.4e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GDMGHCMF_01979 2.7e-62 yrzB - - S - - - Belongs to the UPF0473 family
GDMGHCMF_01980 0.0 - - - S - - - the current gene model (or a revised gene model) may contain a frame shift
GDMGHCMF_01981 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
GDMGHCMF_01982 3.14e-19 - - - - - - - -
GDMGHCMF_01983 6.01e-115 - - - K - - - acetyltransferase
GDMGHCMF_01984 2.54e-149 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GDMGHCMF_01985 2.8e-188 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
GDMGHCMF_01986 8.83e-215 XK27_01785 - - S - - - cog cog1284
GDMGHCMF_01987 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
GDMGHCMF_01989 2.65e-305 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
GDMGHCMF_01990 1.27e-270 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
GDMGHCMF_01991 2.07e-34 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
GDMGHCMF_01992 1.22e-26 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
GDMGHCMF_01994 1.56e-182 yegS - - I - - - Diacylglycerol kinase
GDMGHCMF_01995 6.84e-118 - - - S - - - Hydrophobic domain protein
GDMGHCMF_01998 1.17e-187 - - - L - - - Integrase core domain protein
GDMGHCMF_01999 3.37e-69 copB 3.6.3.4 - P ko:K01533 - ko00000,ko01000 P-type ATPase
GDMGHCMF_02000 1.71e-208 - - - I - - - Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
GDMGHCMF_02001 4.11e-95 usp2 - - T - - - Belongs to the universal stress protein A family
GDMGHCMF_02002 7.84e-88 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
GDMGHCMF_02003 2.53e-96 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
GDMGHCMF_02004 2.72e-38 copZ - - P - - - Heavy-metal-associated domain
GDMGHCMF_02005 0.0 copB 3.6.3.4 - P ko:K01533 - ko00000,ko01000 P-type ATPase
GDMGHCMF_02006 6.06e-67 - - - L ko:K07497 - ko00000 Integrase core domain
GDMGHCMF_02007 2.88e-25 - - - L ko:K07483 - ko00000 Transposase
GDMGHCMF_02008 3.01e-80 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
GDMGHCMF_02009 1.1e-60 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
GDMGHCMF_02010 1.83e-278 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
GDMGHCMF_02011 4.13e-138 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GDMGHCMF_02012 7.81e-149 proWX - - P ko:K05845,ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type proline glycine betaine transport systems, permease component
GDMGHCMF_02013 4.6e-147 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type proline glycine betaine transport systems permease component
GDMGHCMF_02014 4.14e-92 - 3.2.2.10 - L ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
GDMGHCMF_02015 2.1e-114 - - - K - - - Acetyltransferase GNAT Family
GDMGHCMF_02017 1.01e-90 hsp1 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
GDMGHCMF_02018 3.47e-215 - - - L - - - Replication protein
GDMGHCMF_02019 0.0 mycA 4.2.1.53 - S ko:K10254 - ko00000,ko01000 MCRA family
GDMGHCMF_02020 1.46e-68 - - - - - - - -
GDMGHCMF_02021 5.34e-18 - - - - - - - -
GDMGHCMF_02023 2.17e-76 - - - S - - - Uncharacterised lipoprotein family
GDMGHCMF_02024 1.31e-97 tspO - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 TspO/MBR family
GDMGHCMF_02025 1.27e-30 - - - L ko:K07483 - ko00000 transposase IS3 IS911 family protein
GDMGHCMF_02026 4.73e-203 - - - L ko:K07497 - ko00000 EVIDENCE EXPERIMENTAL PMID 1328163 BIO14.04 Transposon related functions. BELONGS TO THE IS3 IS150 IS904 FAMILY OF TRANSPOSASE. There are 7 such elements in the chromosome

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)