ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
HAMMFLPH_00001 5.55e-301 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HAMMFLPH_00002 1.71e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HAMMFLPH_00003 2.24e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
HAMMFLPH_00004 4.54e-264 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HAMMFLPH_00005 1.25e-51 yaaB - - S - - - Domain of unknown function (DUF370)
HAMMFLPH_00006 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HAMMFLPH_00007 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HAMMFLPH_00008 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
HAMMFLPH_00011 4.5e-234 yaaC - - S - - - YaaC-like Protein
HAMMFLPH_00012 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HAMMFLPH_00013 2.81e-316 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HAMMFLPH_00014 3.7e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HAMMFLPH_00015 1.66e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HAMMFLPH_00016 9.79e-296 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HAMMFLPH_00018 3.72e-159 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
HAMMFLPH_00019 2.43e-150 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
HAMMFLPH_00020 7.7e-278 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
HAMMFLPH_00021 1.44e-127 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
HAMMFLPH_00022 1.55e-110 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HAMMFLPH_00023 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HAMMFLPH_00024 8.75e-55 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HAMMFLPH_00025 8.53e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HAMMFLPH_00026 1.55e-42 yaaL - - S - - - Protein of unknown function (DUF2508)
HAMMFLPH_00027 5.3e-49 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
HAMMFLPH_00028 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
HAMMFLPH_00031 2.21e-42 csfB - - S - - - Inhibitor of sigma-G Gin
HAMMFLPH_00032 3.28e-133 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
HAMMFLPH_00033 5.05e-260 yaaN - - P - - - Belongs to the TelA family
HAMMFLPH_00034 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
HAMMFLPH_00035 2.82e-147 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HAMMFLPH_00036 1.02e-72 yaaQ - - S - - - protein conserved in bacteria
HAMMFLPH_00037 1.26e-95 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
HAMMFLPH_00038 2.42e-236 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
HAMMFLPH_00039 1.1e-189 yaaT - - S - - - stage 0 sporulation protein
HAMMFLPH_00040 1.53e-56 yabA - - L - - - Involved in initiation control of chromosome replication
HAMMFLPH_00041 2.81e-178 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
HAMMFLPH_00042 4.19e-65 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
HAMMFLPH_00043 7.26e-208 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HAMMFLPH_00044 1.51e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
HAMMFLPH_00045 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HAMMFLPH_00046 5.05e-185 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
HAMMFLPH_00047 1.91e-283 yabE - - T - - - protein conserved in bacteria
HAMMFLPH_00048 1.05e-127 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HAMMFLPH_00049 1.24e-199 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HAMMFLPH_00050 6.69e-200 yabG - - S ko:K06436 - ko00000 peptidase
HAMMFLPH_00051 5.32e-53 veg - - S - - - protein conserved in bacteria
HAMMFLPH_00052 3.96e-37 sspF - - S ko:K06423 - ko00000 DNA topological change
HAMMFLPH_00053 2.34e-207 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HAMMFLPH_00054 4.66e-196 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
HAMMFLPH_00055 3.45e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
HAMMFLPH_00056 2.45e-63 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HAMMFLPH_00057 9e-310 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HAMMFLPH_00058 1.22e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HAMMFLPH_00059 1.45e-136 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HAMMFLPH_00060 2.03e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HAMMFLPH_00061 6.36e-54 yabK - - S - - - Peptide ABC transporter permease
HAMMFLPH_00062 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HAMMFLPH_00063 5.88e-121 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
HAMMFLPH_00064 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HAMMFLPH_00065 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HAMMFLPH_00066 4.22e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HAMMFLPH_00067 1.91e-66 yabP - - S - - - Sporulation protein YabP
HAMMFLPH_00068 2.21e-139 yabQ - - S - - - spore cortex biosynthesis protein
HAMMFLPH_00069 4.18e-75 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
HAMMFLPH_00070 2.49e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
HAMMFLPH_00073 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
HAMMFLPH_00074 5.61e-168 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
HAMMFLPH_00075 1.25e-238 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
HAMMFLPH_00076 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HAMMFLPH_00077 4.82e-121 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
HAMMFLPH_00078 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HAMMFLPH_00079 6.92e-189 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HAMMFLPH_00080 9.54e-208 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HAMMFLPH_00081 6.68e-196 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
HAMMFLPH_00082 3.77e-218 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HAMMFLPH_00083 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HAMMFLPH_00084 1.03e-137 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
HAMMFLPH_00085 2.27e-216 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
HAMMFLPH_00086 3.32e-205 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HAMMFLPH_00087 2.78e-82 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HAMMFLPH_00088 4.56e-115 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HAMMFLPH_00089 1.81e-41 yazB - - K - - - transcriptional
HAMMFLPH_00090 7.88e-244 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HAMMFLPH_00091 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
HAMMFLPH_00092 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
HAMMFLPH_00102 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
HAMMFLPH_00103 8.72e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
HAMMFLPH_00104 2.76e-65 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
HAMMFLPH_00105 7.74e-257 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HAMMFLPH_00106 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
HAMMFLPH_00107 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HAMMFLPH_00108 3.8e-251 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HAMMFLPH_00109 2.57e-252 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
HAMMFLPH_00110 1.82e-162 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HAMMFLPH_00111 6.35e-113 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HAMMFLPH_00112 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HAMMFLPH_00113 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
HAMMFLPH_00114 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HAMMFLPH_00115 3.52e-96 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HAMMFLPH_00116 4.29e-174 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HAMMFLPH_00117 3.31e-114 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
HAMMFLPH_00118 3.27e-149 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
HAMMFLPH_00119 2.65e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HAMMFLPH_00120 1.37e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
HAMMFLPH_00121 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HAMMFLPH_00122 1.82e-162 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HAMMFLPH_00123 4.03e-104 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HAMMFLPH_00124 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HAMMFLPH_00125 5.1e-140 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
HAMMFLPH_00126 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HAMMFLPH_00127 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HAMMFLPH_00128 1.99e-44 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
HAMMFLPH_00129 6.67e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HAMMFLPH_00130 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HAMMFLPH_00131 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HAMMFLPH_00132 2.01e-287 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HAMMFLPH_00133 8.78e-238 ybaC - - S - - - Alpha/beta hydrolase family
HAMMFLPH_00134 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
HAMMFLPH_00135 7.2e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HAMMFLPH_00136 7.43e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
HAMMFLPH_00137 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HAMMFLPH_00138 2.72e-200 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HAMMFLPH_00139 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HAMMFLPH_00140 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HAMMFLPH_00141 5.9e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HAMMFLPH_00142 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HAMMFLPH_00143 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
HAMMFLPH_00144 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HAMMFLPH_00145 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HAMMFLPH_00146 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HAMMFLPH_00147 7.72e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HAMMFLPH_00148 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HAMMFLPH_00149 3.11e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HAMMFLPH_00150 4.47e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HAMMFLPH_00151 2.89e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HAMMFLPH_00152 9.16e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HAMMFLPH_00153 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
HAMMFLPH_00154 7.32e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
HAMMFLPH_00155 5.7e-298 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HAMMFLPH_00156 6.17e-158 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HAMMFLPH_00157 2.32e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
HAMMFLPH_00158 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HAMMFLPH_00159 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
HAMMFLPH_00160 1.09e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HAMMFLPH_00161 3.24e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HAMMFLPH_00162 7.01e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HAMMFLPH_00163 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
HAMMFLPH_00164 7.5e-200 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HAMMFLPH_00165 2.69e-197 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HAMMFLPH_00166 1.6e-177 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HAMMFLPH_00167 1.51e-182 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HAMMFLPH_00168 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HAMMFLPH_00169 4.28e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
HAMMFLPH_00170 2.14e-186 ybaJ - - Q - - - Methyltransferase domain
HAMMFLPH_00171 2.54e-91 ybaK - - S - - - Protein of unknown function (DUF2521)
HAMMFLPH_00172 2.22e-170 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
HAMMFLPH_00173 1.1e-255 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HAMMFLPH_00174 1.04e-122 gerD - - - ko:K06294 - ko00000 -
HAMMFLPH_00175 5.95e-133 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
HAMMFLPH_00176 4.31e-181 pdaB - - G - - - Polysaccharide deacetylase
HAMMFLPH_00177 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
HAMMFLPH_00184 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
HAMMFLPH_00185 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
HAMMFLPH_00186 0.0 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
HAMMFLPH_00188 3.47e-205 ybaS - - S - - - Na -dependent transporter
HAMMFLPH_00189 4.01e-184 ybbA - - S ko:K07017 - ko00000 Putative esterase
HAMMFLPH_00190 3.51e-228 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HAMMFLPH_00191 2.88e-226 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HAMMFLPH_00192 9.23e-219 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
HAMMFLPH_00193 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
HAMMFLPH_00194 3.6e-306 ybbC - - S - - - protein conserved in bacteria
HAMMFLPH_00195 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
HAMMFLPH_00196 0.0 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
HAMMFLPH_00197 7.29e-304 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HAMMFLPH_00198 3.82e-194 ybbH - - K - - - transcriptional
HAMMFLPH_00199 4.04e-211 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HAMMFLPH_00200 1.55e-114 ybbJ - - J - - - acetyltransferase
HAMMFLPH_00201 4.19e-101 ybbK - - S - - - Protein of unknown function (DUF523)
HAMMFLPH_00207 1.6e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HAMMFLPH_00208 2.73e-152 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HAMMFLPH_00209 5.43e-189 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HAMMFLPH_00210 4.16e-292 ybbR - - S - - - protein conserved in bacteria
HAMMFLPH_00211 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HAMMFLPH_00212 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HAMMFLPH_00213 3.67e-227 alkA 3.2.2.21 - L ko:K01247,ko:K13529 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HAMMFLPH_00214 2.25e-157 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
HAMMFLPH_00215 4.49e-130 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HAMMFLPH_00216 0.0 ndhF 1.6.5.3 - CP ko:K05577 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HAMMFLPH_00217 0.0 ybcC - - S ko:K09822 - ko00000 Belongs to the UPF0753 family
HAMMFLPH_00218 2.51e-125 ybcF - - P - - - carbonic anhydrase
HAMMFLPH_00219 5.59e-64 - - - - - - - -
HAMMFLPH_00220 3.6e-80 ybcI - - S - - - Uncharacterized conserved protein (DUF2294)
HAMMFLPH_00221 9.45e-67 - - - K - - - Helix-turn-helix domain
HAMMFLPH_00222 1.14e-258 ybcL - - EGP ko:K08164 - ko00000,ko02000 COG2814 Arabinose efflux permease
HAMMFLPH_00224 7.24e-304 - - - J - - - 4Fe-4S single cluster domain
HAMMFLPH_00225 0.0 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
HAMMFLPH_00226 8.07e-174 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HAMMFLPH_00227 3.99e-313 skfF - - S - - - ABC transporter
HAMMFLPH_00228 3.88e-118 - - - C - - - HEAT repeats
HAMMFLPH_00229 5.88e-103 - - - CO - - - Thioredoxin-like domain
HAMMFLPH_00230 8.07e-233 - - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HAMMFLPH_00231 2.93e-159 - - - T ko:K02483 - ko00000,ko02022 Transcriptional regulatory protein, C terminal
HAMMFLPH_00232 4.12e-221 - - - T - - - His Kinase A (phospho-acceptor) domain
HAMMFLPH_00234 2.49e-181 ybdM 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 Protein tyrosine kinase
HAMMFLPH_00235 6.61e-196 ybdN - - - - - - -
HAMMFLPH_00236 1.19e-278 ybdO - - S - - - Domain of unknown function (DUF4885)
HAMMFLPH_00237 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
HAMMFLPH_00238 5.46e-51 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
HAMMFLPH_00239 6.92e-41 ybxH - - S - - - Family of unknown function (DUF5370)
HAMMFLPH_00240 3.86e-195 ybxI 3.5.2.6 - V ko:K17838 ko01501,map01501 ko00000,ko00001,ko01000 beta-lactamase
HAMMFLPH_00241 9.97e-317 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
HAMMFLPH_00242 1.11e-54 ybyB - - - - - - -
HAMMFLPH_00243 0.0 ybeC - - E - - - amino acid
HAMMFLPH_00244 7.3e-213 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
HAMMFLPH_00245 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
HAMMFLPH_00246 3.57e-47 - - - S - - - Protein of unknown function (DUF2651)
HAMMFLPH_00247 8.93e-220 ybfA - - K - - - FR47-like protein
HAMMFLPH_00248 2.36e-287 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
HAMMFLPH_00250 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
HAMMFLPH_00251 5.27e-208 ybfH - - EG - - - EamA-like transporter family
HAMMFLPH_00252 7.39e-188 ybfI - - K - - - AraC-like ligand binding domain
HAMMFLPH_00253 5.85e-274 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HAMMFLPH_00254 5.04e-230 mpr - - M - - - Belongs to the peptidase S1B family
HAMMFLPH_00256 2.02e-216 - - - S - - - Alpha/beta hydrolase family
HAMMFLPH_00257 6.9e-124 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HAMMFLPH_00258 7.07e-112 ybfM - - S - - - SNARE associated Golgi protein
HAMMFLPH_00259 4.33e-190 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
HAMMFLPH_00260 2.33e-61 ybfN - - - - - - -
HAMMFLPH_00261 0.0 - - - S ko:K06880 - ko00000,ko01000,ko01504 Erythromycin esterase
HAMMFLPH_00262 5.14e-214 ybfP - - K ko:K13653 - ko00000,ko03000 Transcriptional regulator
HAMMFLPH_00263 1.16e-244 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
HAMMFLPH_00264 4.25e-273 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HAMMFLPH_00265 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HAMMFLPH_00266 7.72e-177 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HAMMFLPH_00267 2.91e-165 - - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
HAMMFLPH_00269 8.08e-260 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
HAMMFLPH_00270 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
HAMMFLPH_00271 2.23e-234 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
HAMMFLPH_00272 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
HAMMFLPH_00273 9.16e-240 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
HAMMFLPH_00274 3.55e-294 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HAMMFLPH_00275 1.72e-217 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
HAMMFLPH_00276 4.1e-222 ycbC 4.2.1.41 - EM ko:K01707 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 5-dehydro-4-deoxyglucarate dehydratase activity
HAMMFLPH_00277 0.0 ycbD - - C ko:K22187 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HAMMFLPH_00278 0.0 gudP - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HAMMFLPH_00279 0.0 gudD 4.2.1.40 - M ko:K01706 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
HAMMFLPH_00280 2.3e-161 ycbG - - K ko:K05799 - ko00000,ko03000 FCD
HAMMFLPH_00281 0.0 garD 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
HAMMFLPH_00282 4.64e-227 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
HAMMFLPH_00283 8.73e-33 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
HAMMFLPH_00284 1.87e-220 eamA1 - - EG - - - spore germination
HAMMFLPH_00285 6.64e-162 ycbL - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HAMMFLPH_00286 1.66e-218 ycbM - - T - - - Histidine kinase
HAMMFLPH_00287 1.66e-216 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HAMMFLPH_00288 4.25e-150 - - - S - - - ABC-2 family transporter protein
HAMMFLPH_00289 2.21e-76 ycbP - - S - - - Protein of unknown function (DUF2512)
HAMMFLPH_00290 1.82e-102 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
HAMMFLPH_00291 4.66e-175 ycbR - - T - - - vWA found in TerF C terminus
HAMMFLPH_00292 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
HAMMFLPH_00293 3.12e-38 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HAMMFLPH_00294 7.6e-160 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HAMMFLPH_00295 2.52e-156 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HAMMFLPH_00296 3.48e-268 ycbU - - E - - - Selenocysteine lyase
HAMMFLPH_00297 2.87e-308 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
HAMMFLPH_00298 6.54e-132 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
HAMMFLPH_00299 8.74e-260 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HAMMFLPH_00300 4e-147 - 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
HAMMFLPH_00301 4.32e-78 - - - S - - - RDD family
HAMMFLPH_00302 2.49e-255 yccF - - K ko:K07039 - ko00000 SEC-C motif
HAMMFLPH_00303 9.56e-217 natK 2.7.13.3 - T ko:K11640 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
HAMMFLPH_00304 6.86e-163 natR - - T ko:K02477,ko:K11641 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
HAMMFLPH_00305 5.41e-171 natA 3.6.3.7 - CP ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
HAMMFLPH_00306 9.75e-258 - - - CP ko:K09696 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
HAMMFLPH_00307 5.83e-223 yccK - - C - - - Aldo keto reductase
HAMMFLPH_00308 1.35e-241 ycdA - - S - - - Domain of unknown function (DUF5105)
HAMMFLPH_00309 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HAMMFLPH_00310 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HAMMFLPH_00311 3.91e-125 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
HAMMFLPH_00312 1.42e-248 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
HAMMFLPH_00313 5.87e-181 - 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
HAMMFLPH_00314 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
HAMMFLPH_00315 1.95e-221 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HAMMFLPH_00316 1.99e-170 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HAMMFLPH_00317 4.63e-173 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HAMMFLPH_00318 9.18e-242 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HAMMFLPH_00319 2.64e-141 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
HAMMFLPH_00320 8.9e-137 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
HAMMFLPH_00321 4.97e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
HAMMFLPH_00322 4.1e-176 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
HAMMFLPH_00323 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
HAMMFLPH_00324 2.96e-245 yceH - - P - - - Belongs to the TelA family
HAMMFLPH_00325 2.32e-279 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
HAMMFLPH_00326 1.17e-267 - - - EGP - - - Uncharacterised MFS-type transporter YbfB
HAMMFLPH_00327 4.82e-61 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HAMMFLPH_00328 8.99e-293 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
HAMMFLPH_00329 2.1e-186 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
HAMMFLPH_00330 2.01e-210 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
HAMMFLPH_00331 2.5e-279 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
HAMMFLPH_00332 0.0 ycgA - - S - - - Membrane
HAMMFLPH_00333 1.25e-127 ycgB - - - - - - -
HAMMFLPH_00334 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
HAMMFLPH_00335 2.06e-233 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HAMMFLPH_00336 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
HAMMFLPH_00337 0.0 mdr - - EGP - - - the major facilitator superfamily
HAMMFLPH_00338 3.7e-101 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
HAMMFLPH_00339 6.42e-147 ycgF - - E - - - Lysine exporter protein LysE YggA
HAMMFLPH_00340 1.85e-195 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
HAMMFLPH_00341 0.0 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
HAMMFLPH_00342 7.6e-145 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
HAMMFLPH_00343 1.83e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HAMMFLPH_00344 1.31e-140 tmrB - - S - - - AAA domain
HAMMFLPH_00345 1.05e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HAMMFLPH_00346 1.29e-186 - - - Q - - - ubiE/COQ5 methyltransferase family
HAMMFLPH_00347 2.05e-230 ycgK - - K ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 LysR substrate binding domain
HAMMFLPH_00348 1.15e-233 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
HAMMFLPH_00349 7.76e-187 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
HAMMFLPH_00350 3.63e-218 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
HAMMFLPH_00351 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
HAMMFLPH_00352 2.64e-316 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HAMMFLPH_00353 3.92e-288 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
HAMMFLPH_00354 3.82e-195 ycgQ - - S ko:K08986 - ko00000 membrane
HAMMFLPH_00355 3.19e-187 ycgR - - S ko:K07089 - ko00000 permeases
HAMMFLPH_00356 4.74e-209 ycgS - - I - - - alpha/beta hydrolase fold
HAMMFLPH_00357 8.9e-247 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
HAMMFLPH_00358 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
HAMMFLPH_00359 1.2e-74 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
HAMMFLPH_00360 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HAMMFLPH_00361 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HAMMFLPH_00362 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
HAMMFLPH_00363 5.51e-283 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
HAMMFLPH_00364 1.05e-222 folE2 3.5.4.16 - S ko:K09007 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Converts GTP to 7,8-dihydroneopterin triphosphate
HAMMFLPH_00365 2.56e-141 - - - M - - - ErfK YbiS YcfS YnhG
HAMMFLPH_00366 6.78e-291 yciC - - S - - - GTPases (G3E family)
HAMMFLPH_00367 2.99e-149 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
HAMMFLPH_00368 3.76e-187 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
HAMMFLPH_00370 5.95e-101 yckC - - S - - - membrane
HAMMFLPH_00371 3.53e-69 yckD - - S - - - Protein of unknown function (DUF2680)
HAMMFLPH_00372 0.0 yckE 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HAMMFLPH_00373 7.06e-93 nin - - S - - - Competence protein J (ComJ)
HAMMFLPH_00374 4.78e-101 nucA - - M - - - Deoxyribonuclease NucA/NucB
HAMMFLPH_00375 6.52e-269 tlpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HAMMFLPH_00376 1.38e-127 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
HAMMFLPH_00377 2.39e-138 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
HAMMFLPH_00378 6.05e-86 hxlR - - K - - - transcriptional
HAMMFLPH_00379 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HAMMFLPH_00380 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HAMMFLPH_00381 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
HAMMFLPH_00382 1.63e-179 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
HAMMFLPH_00383 1.38e-291 - - - EGP - - - Major Facilitator Superfamily
HAMMFLPH_00384 1.61e-126 - - - S - - - YcxB-like protein
HAMMFLPH_00385 1.77e-209 ycxC - - EG - - - EamA-like transporter family
HAMMFLPH_00386 0.0 ycxD - - K - - - GntR family transcriptional regulator
HAMMFLPH_00387 1.37e-144 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
HAMMFLPH_00388 3.04e-148 yczE - - S ko:K07149 - ko00000 membrane
HAMMFLPH_00389 7.11e-172 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
HAMMFLPH_00390 4.6e-157 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
HAMMFLPH_00391 1.5e-188 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
HAMMFLPH_00392 2.17e-208 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
HAMMFLPH_00393 2.33e-142 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HAMMFLPH_00394 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
HAMMFLPH_00395 9.86e-53 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
HAMMFLPH_00396 3.05e-109 yclD - - - - - - -
HAMMFLPH_00397 5.12e-207 yclE 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Alpha beta hydrolase
HAMMFLPH_00398 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
HAMMFLPH_00399 0.0 yclG - - M - - - Pectate lyase superfamily protein
HAMMFLPH_00401 0.0 gerKA - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
HAMMFLPH_00402 8.35e-297 gerKC - - S ko:K06297 - ko00000 spore germination
HAMMFLPH_00403 2.29e-254 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
HAMMFLPH_00404 2.05e-156 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
HAMMFLPH_00405 5.59e-280 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
HAMMFLPH_00406 2.23e-165 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HAMMFLPH_00407 0.0 yclK - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HAMMFLPH_00408 7.71e-98 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
HAMMFLPH_00410 1.58e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
HAMMFLPH_00411 6.5e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
HAMMFLPH_00412 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HAMMFLPH_00413 5.42e-206 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HAMMFLPH_00414 4.69e-211 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HAMMFLPH_00415 5.63e-176 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HAMMFLPH_00416 4.98e-223 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
HAMMFLPH_00417 0.0 ycnB - - EGP - - - the major facilitator superfamily
HAMMFLPH_00418 1.76e-199 ycnC - - K - - - Transcriptional regulator
HAMMFLPH_00419 2.12e-174 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Oxidoreductase
HAMMFLPH_00420 1.68e-60 ycnE - - S - - - Monooxygenase
HAMMFLPH_00421 6.51e-69 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HAMMFLPH_00422 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HAMMFLPH_00423 2.4e-313 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HAMMFLPH_00424 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HAMMFLPH_00425 1.67e-190 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
HAMMFLPH_00426 5.9e-187 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HAMMFLPH_00427 1.07e-138 ycnI - - S - - - protein conserved in bacteria
HAMMFLPH_00428 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
HAMMFLPH_00429 5.18e-139 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
HAMMFLPH_00430 1.34e-74 - - - - - - - -
HAMMFLPH_00431 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
HAMMFLPH_00432 8.3e-95 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
HAMMFLPH_00433 3.77e-269 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
HAMMFLPH_00434 1.01e-256 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
HAMMFLPH_00436 6.21e-97 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HAMMFLPH_00437 2.64e-147 - - - Q - - - COG0412 Dienelactone hydrolase and related enzymes
HAMMFLPH_00438 2.29e-88 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
HAMMFLPH_00440 1.9e-177 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
HAMMFLPH_00441 9.39e-182 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
HAMMFLPH_00442 2.78e-273 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
HAMMFLPH_00443 7e-190 ycsI - - S - - - Belongs to the D-glutamate cyclase family
HAMMFLPH_00444 5.04e-173 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
HAMMFLPH_00445 1.99e-238 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
HAMMFLPH_00446 3.8e-171 kipR - - K - - - Transcriptional regulator
HAMMFLPH_00447 4.18e-154 ycsK - - E - - - anatomical structure formation involved in morphogenesis
HAMMFLPH_00449 7.67e-66 yczJ - - S - - - biosynthesis
HAMMFLPH_00450 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
HAMMFLPH_00451 3.26e-224 ycsN - - S - - - Oxidoreductase
HAMMFLPH_00452 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
HAMMFLPH_00453 0.0 ydaB - - IQ - - - acyl-CoA ligase
HAMMFLPH_00454 6.05e-129 ydaC - - Q - - - Methyltransferase domain
HAMMFLPH_00455 3.74e-207 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HAMMFLPH_00456 2.36e-126 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
HAMMFLPH_00457 6.6e-134 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HAMMFLPH_00458 5.24e-101 ydaG - - S - - - general stress protein
HAMMFLPH_00459 1.31e-178 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HAMMFLPH_00460 1.88e-62 ydzA - - EGP - - - Domain of unknown function (DUF3817)
HAMMFLPH_00461 3.95e-98 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
HAMMFLPH_00462 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HAMMFLPH_00463 3.08e-267 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
HAMMFLPH_00464 1.14e-195 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
HAMMFLPH_00465 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
HAMMFLPH_00466 1.93e-304 ydaM - - M - - - Glycosyl transferase family group 2
HAMMFLPH_00467 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
HAMMFLPH_00468 0.0 ydaO - - E - - - amino acid
HAMMFLPH_00469 3.75e-103 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
HAMMFLPH_00470 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
HAMMFLPH_00471 2.14e-53 - - - - - - - -
HAMMFLPH_00472 3.9e-286 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HAMMFLPH_00473 1.67e-42 ydaS - - S - - - membrane
HAMMFLPH_00474 2.25e-100 ydaT - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
HAMMFLPH_00475 1.06e-190 ydbA - - P - - - EcsC protein family
HAMMFLPH_00476 8.37e-11 gsiB - - S ko:K06884 - ko00000 general stress protein
HAMMFLPH_00477 7.58e-79 ydbB - - G - - - Cupin domain
HAMMFLPH_00478 5.41e-84 ydbC - - S - - - Domain of unknown function (DUF4937
HAMMFLPH_00479 1.35e-198 ydbD - - P ko:K07217 - ko00000 Catalase
HAMMFLPH_00480 3.66e-253 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HAMMFLPH_00481 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
HAMMFLPH_00482 3.39e-155 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
HAMMFLPH_00483 4.43e-290 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HAMMFLPH_00484 3.25e-231 ydbI - - S - - - AI-2E family transporter
HAMMFLPH_00485 2.28e-219 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HAMMFLPH_00486 7.34e-160 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HAMMFLPH_00487 9.32e-70 ydbL - - - - - - -
HAMMFLPH_00488 1.83e-280 ydbM - - I - - - acyl-CoA dehydrogenase
HAMMFLPH_00489 1.49e-26 - - - S - - - Fur-regulated basic protein B
HAMMFLPH_00491 1.91e-202 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HAMMFLPH_00492 4.19e-75 ydbP - - CO - - - Thioredoxin
HAMMFLPH_00493 3.07e-258 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
HAMMFLPH_00494 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HAMMFLPH_00495 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HAMMFLPH_00496 2.12e-107 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
HAMMFLPH_00497 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
HAMMFLPH_00498 2.53e-139 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
HAMMFLPH_00499 1.95e-78 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HAMMFLPH_00500 4.66e-234 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
HAMMFLPH_00501 5.29e-284 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HAMMFLPH_00502 9.49e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HAMMFLPH_00503 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
HAMMFLPH_00504 8.58e-184 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
HAMMFLPH_00505 1.8e-74 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
HAMMFLPH_00506 8.56e-90 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HAMMFLPH_00507 1.31e-243 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
HAMMFLPH_00508 1.97e-70 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
HAMMFLPH_00509 2.48e-111 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HAMMFLPH_00510 1.55e-178 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HAMMFLPH_00511 1.86e-141 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
HAMMFLPH_00515 1.32e-106 ydcG - - S - - - EVE domain
HAMMFLPH_00516 1.54e-101 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HAMMFLPH_00517 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
HAMMFLPH_00518 1.93e-110 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
HAMMFLPH_00526 2.43e-241 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HAMMFLPH_00527 8.15e-94 lrpA - - K ko:K03719 - ko00000,ko03000,ko03036 transcriptional
HAMMFLPH_00528 2.17e-102 lrpB - - K ko:K03719 - ko00000,ko03000,ko03036 transcriptional
HAMMFLPH_00529 1.62e-128 yddQ - - Q - - - Isochorismatase family
HAMMFLPH_00530 1.34e-184 yddR - - S - - - Zn-dependent hydrolases of the beta-lactamase fold
HAMMFLPH_00531 3.35e-288 ydeG3 - - EGP - - - Major Facilitator Superfamily
HAMMFLPH_00536 4.24e-146 ydeA - - S - - - DJ-1/PfpI family
HAMMFLPH_00537 4.22e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
HAMMFLPH_00538 3.57e-103 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
HAMMFLPH_00539 2.47e-47 ydzE - - EG - - - spore germination
HAMMFLPH_00540 3.23e-215 - - - K - - - AraC-like ligand binding domain
HAMMFLPH_00541 4.99e-224 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HAMMFLPH_00542 2.87e-213 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
HAMMFLPH_00543 0.0 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HAMMFLPH_00544 1.19e-280 ydeG - - EGP - - - Major facilitator superfamily
HAMMFLPH_00545 4.76e-72 ydeH - - - - - - -
HAMMFLPH_00546 1.26e-138 ydeI - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
HAMMFLPH_00547 6.11e-150 - - - - - - - -
HAMMFLPH_00548 4.66e-197 ydeK - - EG - - - -transporter
HAMMFLPH_00549 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HAMMFLPH_00550 3.68e-97 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
HAMMFLPH_00551 8.6e-138 - - - S ko:K07002 - ko00000 Serine hydrolase
HAMMFLPH_00552 1.33e-77 - - - K - - - HxlR-like helix-turn-helix
HAMMFLPH_00553 1.68e-196 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
HAMMFLPH_00554 5.03e-91 ydeP - - K - - - Transcriptional regulator
HAMMFLPH_00555 2.44e-142 ywrO - - S ko:K11748 - ko00000,ko02000 NADPH-quinone reductase (modulator of drug activity B)
HAMMFLPH_00556 1.51e-261 ydeR - - EGP - - - Uncharacterised MFS-type transporter YbfB
HAMMFLPH_00557 3.74e-136 ydeS - - K - - - Transcriptional regulator
HAMMFLPH_00558 2.56e-76 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
HAMMFLPH_00559 9.07e-297 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HAMMFLPH_00560 8.05e-191 - - - J - - - GNAT acetyltransferase
HAMMFLPH_00561 3.05e-207 - - - EG - - - EamA-like transporter family
HAMMFLPH_00562 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HAMMFLPH_00563 5.97e-151 ydfE - - S - - - Flavin reductase like domain
HAMMFLPH_00564 5.24e-159 ydfF - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HAMMFLPH_00565 1.37e-104 - - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HAMMFLPH_00567 4.11e-253 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HAMMFLPH_00568 2.3e-142 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HAMMFLPH_00569 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
HAMMFLPH_00570 9.73e-226 - - - S - - - Alpha/beta hydrolase family
HAMMFLPH_00571 6.79e-152 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
HAMMFLPH_00572 2.13e-189 - - - K - - - Bacterial transcription activator, effector binding domain
HAMMFLPH_00573 3.15e-200 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HAMMFLPH_00574 3.45e-145 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
HAMMFLPH_00575 9.49e-239 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
HAMMFLPH_00576 8.02e-84 ydfP - - S ko:K15977 - ko00000 DoxX
HAMMFLPH_00577 9.63e-77 ydfQ - - CO - - - Thioredoxin
HAMMFLPH_00578 2.4e-21 ydgA - - S - - - Spore germination protein gerPA/gerPF
HAMMFLPH_00579 5.33e-39 - - - - - - - -
HAMMFLPH_00581 6.08e-153 ydfR - - S - - - Protein of unknown function (DUF421)
HAMMFLPH_00582 4.44e-160 ydfS - - S - - - Protein of unknown function (DUF421)
HAMMFLPH_00583 3.13e-99 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HAMMFLPH_00584 2.74e-50 ydgA - - S - - - Spore germination protein gerPA/gerPF
HAMMFLPH_00585 2.19e-56 ydgB - - S - - - Spore germination protein gerPA/gerPF
HAMMFLPH_00586 7.86e-132 ydgC - - K - - - Bacterial regulatory proteins, tetR family
HAMMFLPH_00587 3.47e-71 - - - S - - - DoxX-like family
HAMMFLPH_00588 2.49e-114 yycN - - K - - - Acetyltransferase
HAMMFLPH_00589 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
HAMMFLPH_00590 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
HAMMFLPH_00591 5.09e-119 - - - S - - - DinB family
HAMMFLPH_00592 2.06e-104 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HAMMFLPH_00593 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
HAMMFLPH_00594 6.42e-147 ydgI - - C - - - nitroreductase
HAMMFLPH_00595 1.15e-90 - - - K - - - Winged helix DNA-binding domain
HAMMFLPH_00596 5.97e-267 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
HAMMFLPH_00597 1.77e-155 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
HAMMFLPH_00598 5.24e-158 ydhC - - K - - - FCD
HAMMFLPH_00599 8.92e-310 ydhD - - M - - - Glycosyl hydrolase
HAMMFLPH_00600 9.61e-290 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HAMMFLPH_00601 7.71e-166 - - - - - - - -
HAMMFLPH_00602 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
HAMMFLPH_00603 9.93e-91 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
HAMMFLPH_00605 1.43e-112 - - - K - - - Acetyltransferase (GNAT) domain
HAMMFLPH_00606 1.25e-236 ydhJ - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HAMMFLPH_00607 4.01e-130 ydhK - - M - - - Protein of unknown function (DUF1541)
HAMMFLPH_00608 6.3e-255 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
HAMMFLPH_00609 7.97e-65 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HAMMFLPH_00610 6.09e-70 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HAMMFLPH_00611 2.27e-305 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HAMMFLPH_00612 0.0 ydhP 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HAMMFLPH_00613 1.9e-171 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
HAMMFLPH_00614 9.28e-219 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
HAMMFLPH_00615 1.93e-244 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
HAMMFLPH_00616 3.49e-273 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
HAMMFLPH_00617 1.12e-98 ydhU - - P ko:K07217 - ko00000 Catalase
HAMMFLPH_00618 7.94e-22 ydhU - - P ko:K07217 - ko00000 Manganese containing catalase
HAMMFLPH_00621 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
HAMMFLPH_00624 3.06e-237 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HAMMFLPH_00625 9.02e-113 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
HAMMFLPH_00626 1.76e-163 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
HAMMFLPH_00627 1.71e-109 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HAMMFLPH_00628 1.63e-241 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HAMMFLPH_00629 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
HAMMFLPH_00630 1.46e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HAMMFLPH_00631 2.14e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HAMMFLPH_00632 5.48e-31 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HAMMFLPH_00633 8.73e-162 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HAMMFLPH_00634 3.2e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
HAMMFLPH_00635 3e-167 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
HAMMFLPH_00636 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HAMMFLPH_00637 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HAMMFLPH_00639 6.93e-88 - - - KL ko:K06919 - ko00000 Phage plasmid primase P4 family
HAMMFLPH_00640 0.0 dcm 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 DNA (cytosine-5-)-methyltransferase activity
HAMMFLPH_00641 1.43e-297 - 2.1.1.37 - H ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
HAMMFLPH_00643 3.67e-254 - - - V - - - AAA domain (dynein-related subfamily)
HAMMFLPH_00644 0.0 - - - J - - - LlaJI restriction endonuclease
HAMMFLPH_00645 3.73e-11 ydjC - - S - - - Abhydrolase domain containing 18
HAMMFLPH_00646 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
HAMMFLPH_00647 1.06e-258 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
HAMMFLPH_00648 0.0 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
HAMMFLPH_00649 5.39e-224 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
HAMMFLPH_00650 5.36e-148 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
HAMMFLPH_00651 1.04e-227 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HAMMFLPH_00652 3.96e-177 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
HAMMFLPH_00653 1.79e-203 ydjI - - S - - - virion core protein (lumpy skin disease virus)
HAMMFLPH_00654 1.37e-248 - - - S - - - Ion transport 2 domain protein
HAMMFLPH_00655 0.0 iolT - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HAMMFLPH_00656 3.5e-249 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
HAMMFLPH_00657 1.79e-84 ydjM - - M - - - Lytic transglycolase
HAMMFLPH_00658 3.76e-213 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
HAMMFLPH_00660 8.2e-48 ydjO - - S - - - Cold-inducible protein YdjO
HAMMFLPH_00661 3.21e-205 - - - I - - - Alpha/beta hydrolase family
HAMMFLPH_00662 1.9e-233 yeaA - - S - - - Protein of unknown function (DUF4003)
HAMMFLPH_00663 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
HAMMFLPH_00664 0.0 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
HAMMFLPH_00665 6.13e-199 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HAMMFLPH_00666 1.18e-227 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
HAMMFLPH_00667 6.74e-287 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
HAMMFLPH_00668 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
HAMMFLPH_00669 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
HAMMFLPH_00670 1.2e-283 pbuG - - S ko:K06901 - ko00000,ko02000 permease
HAMMFLPH_00671 1.44e-165 yebC - - M - - - Membrane
HAMMFLPH_00673 2.66e-120 yebE - - S - - - UPF0316 protein
HAMMFLPH_00674 3.13e-38 yebG - - S - - - NETI protein
HAMMFLPH_00675 2.28e-108 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HAMMFLPH_00676 9.39e-278 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HAMMFLPH_00677 6.85e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HAMMFLPH_00678 1.06e-170 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
HAMMFLPH_00679 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HAMMFLPH_00680 1.15e-167 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HAMMFLPH_00681 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HAMMFLPH_00682 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HAMMFLPH_00683 4.2e-241 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
HAMMFLPH_00684 4.4e-138 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HAMMFLPH_00685 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
HAMMFLPH_00686 2.07e-300 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
HAMMFLPH_00687 5.26e-96 - - - K - - - helix_turn_helix ASNC type
HAMMFLPH_00688 1.91e-297 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
HAMMFLPH_00689 3.45e-37 - - - S - - - Protein of unknown function (DUF2892)
HAMMFLPH_00690 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
HAMMFLPH_00691 7.03e-246 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
HAMMFLPH_00692 7.62e-68 yerC - - S - - - protein conserved in bacteria
HAMMFLPH_00693 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
HAMMFLPH_00695 1.1e-161 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HAMMFLPH_00696 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
HAMMFLPH_00697 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HAMMFLPH_00698 1.77e-281 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
HAMMFLPH_00699 6.28e-253 yerI - - S - - - homoserine kinase type II (protein kinase fold)
HAMMFLPH_00700 2.29e-160 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
HAMMFLPH_00701 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HAMMFLPH_00702 7.37e-61 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HAMMFLPH_00703 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HAMMFLPH_00704 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HAMMFLPH_00705 2.93e-201 yerO - - K - - - Transcriptional regulator
HAMMFLPH_00706 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HAMMFLPH_00707 1.8e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HAMMFLPH_00708 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HAMMFLPH_00709 3.63e-127 - - - L - - - Recombinase
HAMMFLPH_00710 5.61e-71 - - - L - - - Resolvase, N terminal domain
HAMMFLPH_00711 0.0 yeeA - - V - - - Type II restriction enzyme, methylase subunits
HAMMFLPH_00712 0.0 - - - L - - - DEAD-like helicases superfamily
HAMMFLPH_00713 1.13e-270 yeeC - - P - - - T5orf172
HAMMFLPH_00714 7.48e-05 - - - - - - - -
HAMMFLPH_00715 4.15e-42 - - - S - - - Colicin immunity protein / pyocin immunity protein
HAMMFLPH_00716 2.1e-109 - - - S - - - Protein of unknown function, DUF600
HAMMFLPH_00717 0.0 - - - L - - - nucleic acid phosphodiester bond hydrolysis
HAMMFLPH_00718 1.73e-246 - 3.4.24.40 - CO ko:K01406 ko01503,map01503 ko00000,ko00001,ko01000,ko01002 amine dehydrogenase activity
HAMMFLPH_00719 1.33e-275 rapH - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Tetratricopeptide repeat
HAMMFLPH_00721 1.09e-162 yeeN - - K - - - transcriptional regulatory protein
HAMMFLPH_00723 1.86e-134 dhaR3 - - K ko:K16137 - ko00000,ko03000 Transcriptional regulator
HAMMFLPH_00724 4.95e-107 yesE - - S ko:K06893 - ko00000 SnoaL-like domain
HAMMFLPH_00725 8.81e-206 yesF - - GM - - - NAD(P)H-binding
HAMMFLPH_00726 3.8e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
HAMMFLPH_00727 2.31e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
HAMMFLPH_00728 1.04e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
HAMMFLPH_00729 1.76e-132 yesJ - - K - - - Acetyltransferase (GNAT) family
HAMMFLPH_00731 3.52e-135 yesL - - S - - - Protein of unknown function, DUF624
HAMMFLPH_00732 0.0 yesM 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HAMMFLPH_00733 5.07e-260 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
HAMMFLPH_00734 8.76e-316 yesO - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
HAMMFLPH_00735 2.02e-218 yesP - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HAMMFLPH_00736 1.31e-212 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HAMMFLPH_00737 6.85e-255 - 3.2.1.172 GH105 S ko:K15532 - ko00000,ko01000 Glycosyl Hydrolase Family 88
HAMMFLPH_00738 0.0 yesS - - K - - - Transcriptional regulator
HAMMFLPH_00739 3.56e-171 - - - E - - - GDSL-like Lipase/Acylhydrolase
HAMMFLPH_00740 1.41e-169 yesU - - S - - - Domain of unknown function (DUF1961)
HAMMFLPH_00741 3.44e-146 - - - S - - - Protein of unknown function, DUF624
HAMMFLPH_00742 0.0 - 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
HAMMFLPH_00743 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
HAMMFLPH_00744 9.13e-160 - - - E - - - GDSL-like Lipase/Acylhydrolase
HAMMFLPH_00745 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
HAMMFLPH_00746 0.0 yetA - - - - - - -
HAMMFLPH_00747 0.0 lplA - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HAMMFLPH_00748 1.01e-227 lplB - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
HAMMFLPH_00749 7.85e-209 - - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HAMMFLPH_00750 0.0 - 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
HAMMFLPH_00751 3.13e-158 yetF - - S - - - membrane
HAMMFLPH_00752 4.67e-73 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
HAMMFLPH_00753 2.47e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HAMMFLPH_00754 9.79e-45 - - - - - - - -
HAMMFLPH_00755 3.87e-114 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HAMMFLPH_00756 1.97e-54 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HAMMFLPH_00757 3.81e-28 yezD - - S - - - Uncharacterized small protein (DUF2292)
HAMMFLPH_00758 2.55e-135 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
HAMMFLPH_00759 7.35e-203 - - - EG - - - EamA-like transporter family
HAMMFLPH_00760 6.74e-117 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
HAMMFLPH_00761 4.77e-270 yetM - - CH - - - FAD binding domain
HAMMFLPH_00762 6.1e-255 yetN - - S - - - Protein of unknown function (DUF3900)
HAMMFLPH_00763 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
HAMMFLPH_00764 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
HAMMFLPH_00765 2.15e-190 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
HAMMFLPH_00766 4.79e-220 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
HAMMFLPH_00767 9.79e-232 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
HAMMFLPH_00768 2.44e-286 yfnE - - S - - - Glycosyltransferase like family 2
HAMMFLPH_00769 2.84e-244 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
HAMMFLPH_00770 6.21e-268 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HAMMFLPH_00771 9.43e-171 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
HAMMFLPH_00772 4.16e-313 yfnA - - E ko:K03294 - ko00000 amino acid
HAMMFLPH_00773 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HAMMFLPH_00774 5.14e-161 yfmS - - NT - - - chemotaxis protein
HAMMFLPH_00775 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HAMMFLPH_00776 6.48e-99 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
HAMMFLPH_00777 3.03e-91 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
HAMMFLPH_00778 3.59e-265 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
HAMMFLPH_00779 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HAMMFLPH_00780 1.86e-266 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
HAMMFLPH_00781 1.86e-107 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
HAMMFLPH_00782 4.21e-242 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
HAMMFLPH_00783 1.72e-268 - - - G - - - Major Facilitator Superfamily
HAMMFLPH_00784 0.0 pkn1 - - S - - - Sulfatase-modifying factor enzyme 1
HAMMFLPH_00785 1.4e-192 fhuC 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
HAMMFLPH_00786 2.1e-223 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HAMMFLPH_00787 2.85e-221 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HAMMFLPH_00788 2.88e-221 yfmC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
HAMMFLPH_00789 1.06e-31 - - - S - - - Protein of unknown function (DUF3212)
HAMMFLPH_00790 1.71e-76 yflT - - S - - - Heat induced stress protein YflT
HAMMFLPH_00791 2.45e-307 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
HAMMFLPH_00792 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
HAMMFLPH_00793 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
HAMMFLPH_00794 3.96e-154 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
HAMMFLPH_00795 1.45e-232 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
HAMMFLPH_00797 5.35e-288 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
HAMMFLPH_00798 7.21e-194 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
HAMMFLPH_00799 6.81e-276 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HAMMFLPH_00800 2.54e-60 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
HAMMFLPH_00801 2.51e-159 yflK - - S - - - protein conserved in bacteria
HAMMFLPH_00802 1.1e-25 yflJ - - S - - - Protein of unknown function (DUF2639)
HAMMFLPH_00803 6.9e-27 yflI - - - - - - -
HAMMFLPH_00804 3.63e-66 yflH - - S - - - Protein of unknown function (DUF3243)
HAMMFLPH_00805 1.14e-178 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
HAMMFLPH_00806 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HAMMFLPH_00807 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
HAMMFLPH_00808 1.89e-87 ydhN1 - - S - - - Domain of unknown function (DUF1992)
HAMMFLPH_00809 0.0 yflA - - E ko:K03310 - ko00000 Sodium alanine symporter
HAMMFLPH_00810 2.19e-249 yfkT - - E ko:K06309 - ko00000 Spore germination protein
HAMMFLPH_00812 2.28e-271 yfkR - - S ko:K06297,ko:K06308 - ko00000 spore germination
HAMMFLPH_00813 0.0 yfkQ - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
HAMMFLPH_00814 0.0 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HAMMFLPH_00815 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
HAMMFLPH_00816 1.24e-172 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
HAMMFLPH_00817 5.27e-161 frp - - C - - - nitroreductase
HAMMFLPH_00818 0.0 yfkN 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HAMMFLPH_00819 8.44e-118 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
HAMMFLPH_00820 6.21e-266 ydiN3 - - EGP - - - COG0477 Permeases of the major facilitator superfamily
HAMMFLPH_00821 7.27e-42 yfkK - - S - - - Belongs to the UPF0435 family
HAMMFLPH_00822 2.14e-110 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HAMMFLPH_00823 2.53e-67 yfkI - - S - - - gas vesicle protein
HAMMFLPH_00824 9.64e-184 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
HAMMFLPH_00825 1.64e-12 - - - - - - - -
HAMMFLPH_00826 1.9e-278 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
HAMMFLPH_00827 1.34e-235 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
HAMMFLPH_00828 3.69e-189 yfkD - - S - - - YfkD-like protein
HAMMFLPH_00829 4.44e-191 yfkC - - M - - - Mechanosensitive ion channel
HAMMFLPH_00830 1.76e-283 yfkA - - S - - - YfkB-like domain
HAMMFLPH_00831 3.26e-36 yfjT - - - - - - -
HAMMFLPH_00832 7.24e-198 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
HAMMFLPH_00833 4.82e-194 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HAMMFLPH_00834 7.8e-237 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
HAMMFLPH_00835 1.94e-214 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HAMMFLPH_00836 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HAMMFLPH_00837 3e-53 - - - S - - - YfzA-like protein
HAMMFLPH_00838 1.21e-243 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HAMMFLPH_00839 9.55e-111 yfjM - - S - - - Psort location Cytoplasmic, score
HAMMFLPH_00841 1.36e-244 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HAMMFLPH_00842 2.75e-244 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HAMMFLPH_00843 4.19e-265 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HAMMFLPH_00844 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HAMMFLPH_00845 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
HAMMFLPH_00846 8.16e-36 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
HAMMFLPH_00847 7.42e-75 yfjF - - S ko:K09771 - ko00000,ko02000 UPF0060 membrane protein
HAMMFLPH_00848 1.53e-104 - - - S - - - Family of unknown function (DUF5381)
HAMMFLPH_00849 1.49e-131 yfjD - - S - - - Family of unknown function (DUF5381)
HAMMFLPH_00850 2.5e-185 yfjC - - - - - - -
HAMMFLPH_00851 1.94e-270 yfjB - - - - - - -
HAMMFLPH_00852 5.59e-61 yfjA - - S - - - Belongs to the WXG100 family
HAMMFLPH_00853 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HAMMFLPH_00854 7.45e-182 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
HAMMFLPH_00855 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HAMMFLPH_00856 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
HAMMFLPH_00857 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HAMMFLPH_00858 2.01e-84 yfiD3 - - S - - - DoxX
HAMMFLPH_00859 7.28e-209 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
HAMMFLPH_00860 1.28e-228 - - - K ko:K02099 - ko00000,ko03000 AraC-like ligand binding domain
HAMMFLPH_00861 0.0 yfiG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HAMMFLPH_00862 5.47e-234 - - - G - - - Xylose isomerase
HAMMFLPH_00863 5.17e-295 - - - S - - - Oxidoreductase
HAMMFLPH_00865 7.54e-276 baeS - - T - - - Histidine kinase
HAMMFLPH_00866 1.05e-146 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
HAMMFLPH_00867 3.35e-218 drrA - - V ko:K01990,ko:K09695 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HAMMFLPH_00868 3.66e-274 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HAMMFLPH_00869 4.56e-267 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
HAMMFLPH_00870 1.89e-128 padR - - K - - - transcriptional
HAMMFLPH_00871 7.87e-128 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
HAMMFLPH_00872 2.29e-253 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HAMMFLPH_00873 4.18e-141 yfiR - - K - - - Transcriptional regulator
HAMMFLPH_00874 4.51e-281 yfiS - - EGP - - - Major facilitator superfamily
HAMMFLPH_00875 2.41e-129 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
HAMMFLPH_00876 0.0 yfiU - - EGP - - - the major facilitator superfamily
HAMMFLPH_00877 5.39e-106 yfiV - - K - - - transcriptional
HAMMFLPH_00878 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HAMMFLPH_00879 2.81e-233 yfiY - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HAMMFLPH_00880 1.54e-225 yfiZ - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HAMMFLPH_00881 5.18e-229 yfhA - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HAMMFLPH_00882 7.61e-215 yfhB - - S - - - PhzF family
HAMMFLPH_00883 2.87e-138 yfhC - - C - - - nitroreductase
HAMMFLPH_00884 8.86e-35 yfhD - - S - - - YfhD-like protein
HAMMFLPH_00886 1.13e-221 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
HAMMFLPH_00887 3.25e-181 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
HAMMFLPH_00888 4.58e-69 yfhH - - S - - - Protein of unknown function (DUF1811)
HAMMFLPH_00890 2.45e-268 yfhI - - EGP - - - -transporter
HAMMFLPH_00891 2.25e-27 sspK - - S ko:K06428 - ko00000 reproduction
HAMMFLPH_00892 8.95e-60 yfhJ - - S - - - WVELL protein
HAMMFLPH_00893 3.58e-119 yfhK - - T - - - Bacterial SH3 domain homologues
HAMMFLPH_00894 5.4e-67 yfhL - - S - - - SdpI/YhfL protein family
HAMMFLPH_00895 3.37e-219 yfhM 3.8.1.5 - S ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Alpha beta hydrolase
HAMMFLPH_00896 3.43e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
HAMMFLPH_00897 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
HAMMFLPH_00898 7.22e-237 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
HAMMFLPH_00899 8.47e-268 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
HAMMFLPH_00900 1.73e-48 yfhS - - - - - - -
HAMMFLPH_00901 3.13e-172 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HAMMFLPH_00902 2.35e-14 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
HAMMFLPH_00903 2.01e-49 ygaB - - S - - - YgaB-like protein
HAMMFLPH_00904 8.1e-136 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
HAMMFLPH_00905 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
HAMMFLPH_00906 1.87e-238 ygaE - - S - - - Membrane
HAMMFLPH_00907 1.19e-314 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
HAMMFLPH_00908 2.92e-113 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
HAMMFLPH_00909 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
HAMMFLPH_00910 4.67e-75 ygzB - - S - - - UPF0295 protein
HAMMFLPH_00911 8.23e-215 ygxA - - S - - - Nucleotidyltransferase-like
HAMMFLPH_00912 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
HAMMFLPH_00929 2.22e-185 spo0M - - S ko:K06377 - ko00000 COG4326 Sporulation control protein
HAMMFLPH_00930 3.88e-37 - - - - - - - -
HAMMFLPH_00931 6.95e-173 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
HAMMFLPH_00932 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HAMMFLPH_00933 0.0 ygaK - - C - - - Berberine and berberine like
HAMMFLPH_00935 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
HAMMFLPH_00936 4.15e-185 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HAMMFLPH_00937 1.78e-219 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
HAMMFLPH_00938 5.86e-190 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HAMMFLPH_00939 9.35e-276 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
HAMMFLPH_00941 4.82e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HAMMFLPH_00942 2.79e-102 ygaO - - - - - - -
HAMMFLPH_00943 1.48e-39 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
HAMMFLPH_00945 1.92e-147 yhzB - - S - - - B3/4 domain
HAMMFLPH_00946 5.09e-285 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HAMMFLPH_00947 4.79e-226 yhbB - - S - - - Putative amidase domain
HAMMFLPH_00948 6.53e-113 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HAMMFLPH_00949 3.4e-143 yhbD - - K - - - Protein of unknown function (DUF4004)
HAMMFLPH_00950 2.29e-96 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
HAMMFLPH_00951 4.08e-110 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
HAMMFLPH_00952 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
HAMMFLPH_00953 1.21e-286 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
HAMMFLPH_00954 1.29e-101 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
HAMMFLPH_00955 3.8e-133 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
HAMMFLPH_00956 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
HAMMFLPH_00957 4.87e-128 yhcB 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 Belongs to the WrbA family
HAMMFLPH_00958 3.95e-59 yhcC - - - - - - -
HAMMFLPH_00959 2.92e-69 - - - - - - - -
HAMMFLPH_00960 1.67e-79 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
HAMMFLPH_00961 3.38e-158 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HAMMFLPH_00962 6.47e-213 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HAMMFLPH_00963 3.45e-212 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HAMMFLPH_00964 1.91e-42 cspB - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
HAMMFLPH_00965 1.34e-195 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
HAMMFLPH_00966 2.47e-251 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
HAMMFLPH_00967 2.62e-301 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HAMMFLPH_00968 3.23e-80 yhcM - - - - - - -
HAMMFLPH_00969 2.69e-111 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HAMMFLPH_00970 3.96e-227 yhcP - - - - - - -
HAMMFLPH_00971 1.68e-146 yhcQ - - M - - - Spore coat protein
HAMMFLPH_00972 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HAMMFLPH_00973 3.9e-138 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
HAMMFLPH_00974 8.26e-219 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
HAMMFLPH_00975 4.27e-89 yhcU - - S - - - Family of unknown function (DUF5365)
HAMMFLPH_00976 1.76e-90 yhcV - - S - - - COG0517 FOG CBS domain
HAMMFLPH_00977 3.04e-155 yhcW - - S ko:K07025 - ko00000 hydrolase
HAMMFLPH_00978 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HAMMFLPH_00979 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HAMMFLPH_00980 5.35e-135 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HAMMFLPH_00981 5.7e-196 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HAMMFLPH_00982 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HAMMFLPH_00983 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HAMMFLPH_00984 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
HAMMFLPH_00985 2.29e-273 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
HAMMFLPH_00986 5.68e-148 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HAMMFLPH_00987 5.68e-117 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
HAMMFLPH_00988 1.65e-51 yhdB - - S - - - YhdB-like protein
HAMMFLPH_00989 1.25e-72 yhdC - - S - - - Protein of unknown function (DUF3889)
HAMMFLPH_00990 2.4e-275 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
HAMMFLPH_00991 1.37e-99 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
HAMMFLPH_00992 5.29e-307 ygxB - - M - - - Conserved TM helix
HAMMFLPH_00993 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
HAMMFLPH_00994 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
HAMMFLPH_00995 7.21e-204 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
HAMMFLPH_00996 4.93e-210 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
HAMMFLPH_00997 5.51e-263 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
HAMMFLPH_00998 1.41e-208 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HAMMFLPH_00999 8.94e-317 yhdG - - E ko:K03294 - ko00000 amino acid
HAMMFLPH_01000 4.29e-310 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HAMMFLPH_01001 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HAMMFLPH_01002 1.75e-100 - - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HAMMFLPH_01003 4.27e-59 yhdK - - S - - - Sigma-M inhibitor protein
HAMMFLPH_01004 6.13e-258 yhdL - - S - - - Sigma factor regulator N-terminal
HAMMFLPH_01005 3.24e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HAMMFLPH_01006 6.74e-244 yhdN - - C - - - Aldo keto reductase
HAMMFLPH_01007 3.9e-143 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HAMMFLPH_01008 2.18e-304 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
HAMMFLPH_01009 3.44e-97 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
HAMMFLPH_01010 4.37e-285 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
HAMMFLPH_01011 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
HAMMFLPH_01012 2.69e-70 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HAMMFLPH_01013 1.01e-87 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HAMMFLPH_01014 5.44e-174 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
HAMMFLPH_01015 3.7e-09 yhdX - - S - - - Uncharacterized protein YhdX
HAMMFLPH_01016 4.51e-260 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
HAMMFLPH_01017 2.93e-180 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HAMMFLPH_01018 5.7e-200 nodB1 - - G - - - deacetylase
HAMMFLPH_01019 2.23e-197 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HAMMFLPH_01020 3.94e-307 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
HAMMFLPH_01021 3.85e-109 nhaX - - T - - - Belongs to the universal stress protein A family
HAMMFLPH_01022 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HAMMFLPH_01023 0.0 yheH - - V ko:K06147,ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HAMMFLPH_01024 3.31e-143 yheG - - GM - - - NAD(P)H-binding
HAMMFLPH_01025 1.25e-38 sspB - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
HAMMFLPH_01026 2.27e-49 yheE - - S - - - Family of unknown function (DUF5342)
HAMMFLPH_01027 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
HAMMFLPH_01028 3.37e-276 yheC - - HJ - - - YheC/D like ATP-grasp
HAMMFLPH_01029 1.51e-261 yheB - - S - - - Belongs to the UPF0754 family
HAMMFLPH_01030 7.46e-72 yheA - - S - - - Belongs to the UPF0342 family
HAMMFLPH_01031 6.69e-264 yhaZ - - L - - - DNA alkylation repair enzyme
HAMMFLPH_01032 8.7e-198 yhaX - - S - - - haloacid dehalogenase-like hydrolase
HAMMFLPH_01033 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
HAMMFLPH_01034 1.85e-267 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
HAMMFLPH_01035 6.51e-114 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
HAMMFLPH_01037 1.6e-172 yhaR - - I - - - enoyl-CoA hydratase
HAMMFLPH_01038 2.29e-36 - - - S - - - YhzD-like protein
HAMMFLPH_01039 5.56e-215 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HAMMFLPH_01040 5.14e-272 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
HAMMFLPH_01041 9.85e-303 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
HAMMFLPH_01042 0.0 yhaN - - L - - - AAA domain
HAMMFLPH_01043 5.22e-228 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
HAMMFLPH_01044 1.88e-39 yhaL - - S - - - Sporulation protein YhaL
HAMMFLPH_01045 2.29e-179 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HAMMFLPH_01046 1.4e-116 yhaK - - S - - - Putative zincin peptidase
HAMMFLPH_01047 8.48e-73 yhaI - - S - - - Protein of unknown function (DUF1878)
HAMMFLPH_01048 4.92e-148 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
HAMMFLPH_01049 1.74e-54 yhaH - - S - - - YtxH-like protein
HAMMFLPH_01050 6.32e-104 trpP - - S - - - Tryptophan transporter TrpP
HAMMFLPH_01051 1.84e-262 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HAMMFLPH_01052 3.5e-106 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HAMMFLPH_01053 2.7e-176 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
HAMMFLPH_01054 3.11e-272 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
HAMMFLPH_01055 5e-162 ecsC - - S - - - EcsC protein family
HAMMFLPH_01056 4.8e-295 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HAMMFLPH_01057 8.98e-317 yhfA - - C - - - membrane
HAMMFLPH_01058 1.33e-23 - - - C - - - Rubrerythrin
HAMMFLPH_01059 1.31e-118 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
HAMMFLPH_01060 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HAMMFLPH_01061 7.78e-261 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HAMMFLPH_01062 2.06e-232 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
HAMMFLPH_01063 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HAMMFLPH_01064 3.49e-133 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
HAMMFLPH_01065 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
HAMMFLPH_01066 8.77e-237 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HAMMFLPH_01067 1.61e-178 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
HAMMFLPH_01068 2.68e-253 yhfE - - G - - - peptidase M42
HAMMFLPH_01069 3.75e-94 - - - S - - - ASCH
HAMMFLPH_01070 4.77e-289 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HAMMFLPH_01071 5.93e-183 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
HAMMFLPH_01072 1.21e-246 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
HAMMFLPH_01073 1.82e-144 yhfK - - GM - - - NmrA-like family
HAMMFLPH_01074 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
HAMMFLPH_01075 2.78e-85 yhfM - - - - - - -
HAMMFLPH_01076 9.64e-308 yhfN - - O - - - Peptidase M48
HAMMFLPH_01077 2.94e-261 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HAMMFLPH_01078 2.75e-105 - - - K - - - acetyltransferase
HAMMFLPH_01079 2.4e-232 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
HAMMFLPH_01080 2.77e-223 yhfQ - - M ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
HAMMFLPH_01081 9.64e-141 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
HAMMFLPH_01082 1.19e-256 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
HAMMFLPH_01083 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
HAMMFLPH_01084 1.47e-118 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
HAMMFLPH_01085 1.85e-260 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
HAMMFLPH_01086 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
HAMMFLPH_01087 7.82e-204 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HAMMFLPH_01088 9.84e-45 yhzC - - S - - - IDEAL
HAMMFLPH_01089 2.19e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
HAMMFLPH_01090 2.55e-216 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
HAMMFLPH_01091 5e-57 yhjA - - S - - - Excalibur calcium-binding domain
HAMMFLPH_01092 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HAMMFLPH_01093 1.61e-36 yhjC - - S - - - Protein of unknown function (DUF3311)
HAMMFLPH_01094 2.57e-78 yhjD - - - - - - -
HAMMFLPH_01095 4.87e-141 yhjE - - S - - - SNARE associated Golgi protein
HAMMFLPH_01096 3.09e-118 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HAMMFLPH_01097 0.0 yhjG - - CH - - - FAD binding domain
HAMMFLPH_01098 2.82e-122 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
HAMMFLPH_01099 3.12e-273 glcP - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
HAMMFLPH_01100 3.98e-257 - 1.1.1.18, 1.1.1.361, 1.1.1.369 - S ko:K00010,ko:K18652 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
HAMMFLPH_01101 2.63e-205 ntdB 3.1.3.24, 3.1.3.92 - S ko:K07024,ko:K18654 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose-6F-phosphate phosphohydrolase
HAMMFLPH_01102 0.0 - 2.6.1.104 - E ko:K18653 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
HAMMFLPH_01103 1.07e-239 yhjM - - K - - - Transcriptional regulator
HAMMFLPH_01104 2.14e-260 yhjN - - S ko:K07120 - ko00000 membrane
HAMMFLPH_01105 1.27e-272 - - - EGP - - - Transmembrane secretion effector
HAMMFLPH_01106 0.0 - - - S - - - Sugar transport-related sRNA regulator N-term
HAMMFLPH_01107 3.54e-77 yhjQ - - C - - - COG1145 Ferredoxin
HAMMFLPH_01108 9.3e-102 yhjR - - S - - - Rubrerythrin
HAMMFLPH_01109 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
HAMMFLPH_01110 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
HAMMFLPH_01111 1.2e-281 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HAMMFLPH_01112 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
HAMMFLPH_01113 1.34e-66 yisB - - V - - - COG1403 Restriction endonuclease
HAMMFLPH_01114 3.3e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
HAMMFLPH_01115 4.08e-88 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
HAMMFLPH_01116 7.36e-34 gerPD - - S ko:K06302 - ko00000 Spore germination protein
HAMMFLPH_01117 8.23e-93 gerPC - - S ko:K06301 - ko00000 Spore germination protein
HAMMFLPH_01118 1.76e-47 gerPB - - S ko:K06300 - ko00000 cell differentiation
HAMMFLPH_01119 1.82e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
HAMMFLPH_01120 1.52e-32 yisI - - S - - - Spo0E like sporulation regulatory protein
HAMMFLPH_01121 3.96e-224 cotH - - M ko:K06330 - ko00000 Spore Coat
HAMMFLPH_01122 2.66e-219 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HAMMFLPH_01123 1.02e-74 yisL - - S - - - UPF0344 protein
HAMMFLPH_01124 0.0 wprA - - O ko:K13274 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HAMMFLPH_01125 7.48e-137 yisN - - S - - - Protein of unknown function (DUF2777)
HAMMFLPH_01126 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
HAMMFLPH_01127 1.85e-115 yizA - - S - - - Damage-inducible protein DinB
HAMMFLPH_01128 6.82e-193 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
HAMMFLPH_01129 1.01e-310 yisQ - - V - - - Mate efflux family protein
HAMMFLPH_01130 1.41e-207 yisR - - K - - - Transcriptional regulator
HAMMFLPH_01131 1.83e-235 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HAMMFLPH_01132 9.72e-254 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
HAMMFLPH_01133 7.28e-122 yisT - - S - - - DinB family
HAMMFLPH_01134 5.42e-140 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
HAMMFLPH_01135 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HAMMFLPH_01136 2.15e-96 yisX - - S - - - Pentapeptide repeats (9 copies)
HAMMFLPH_01137 2.25e-199 yisY 1.11.1.10 - I ko:K00433 - ko00000,ko01000 hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HAMMFLPH_01138 4.06e-145 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
HAMMFLPH_01139 1.37e-295 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
HAMMFLPH_01140 9.51e-185 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
HAMMFLPH_01141 1.34e-162 - 3.1.3.71 - H ko:K05979 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the ComB family
HAMMFLPH_01142 4.31e-180 yitD 4.4.1.19 - S ko:K08097 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 synthase
HAMMFLPH_01143 6.77e-145 yitE - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
HAMMFLPH_01144 2.14e-283 yitF 5.5.1.27 - M ko:K18983 ko00053,map00053 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
HAMMFLPH_01145 1.01e-291 yitG - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HAMMFLPH_01146 7.86e-207 yitH - - K - - - Acetyltransferase (GNAT) domain
HAMMFLPH_01147 3.34e-106 - - - S - - - Acetyltransferase (GNAT) domain
HAMMFLPH_01148 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HAMMFLPH_01149 1.06e-77 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
HAMMFLPH_01150 1.94e-204 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
HAMMFLPH_01151 4.16e-122 - - - - - - - -
HAMMFLPH_01152 1.42e-218 - - - - - - - -
HAMMFLPH_01153 3.29e-127 - - - S - - - Sporulation delaying protein SdpA
HAMMFLPH_01154 2.08e-77 - - - K - - - Transcriptional regulator PadR-like family
HAMMFLPH_01155 7.76e-123 - - - - - - - -
HAMMFLPH_01156 4.59e-59 yitR - - S - - - Domain of unknown function (DUF3784)
HAMMFLPH_01157 0.0 nprB 3.4.24.28 - E ko:K01400,ko:K08777 ko02024,map02024 ko00000,ko00001,ko01000,ko01002 Peptidase M4
HAMMFLPH_01158 9.13e-202 yitS - - S - - - protein conserved in bacteria
HAMMFLPH_01159 2.29e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
HAMMFLPH_01160 1.61e-92 ipi - - S - - - Intracellular proteinase inhibitor
HAMMFLPH_01161 1.01e-25 - - - S - - - Protein of unknown function (DUF3813)
HAMMFLPH_01162 3.19e-200 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
HAMMFLPH_01163 5.05e-185 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
HAMMFLPH_01164 3.26e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
HAMMFLPH_01165 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
HAMMFLPH_01166 3.24e-114 yitZ - - G - - - Major Facilitator Superfamily
HAMMFLPH_01167 9.02e-256 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HAMMFLPH_01168 7.4e-295 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HAMMFLPH_01169 5.4e-177 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
HAMMFLPH_01170 1.69e-278 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
HAMMFLPH_01171 1.4e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
HAMMFLPH_01172 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
HAMMFLPH_01173 3.66e-226 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HAMMFLPH_01174 2.51e-39 yjzC - - S - - - YjzC-like protein
HAMMFLPH_01175 2.17e-23 yjzD - - S - - - Protein of unknown function (DUF2929)
HAMMFLPH_01176 2.42e-182 yjaU - - I - - - carboxylic ester hydrolase activity
HAMMFLPH_01177 5.41e-134 yjaV - - - - - - -
HAMMFLPH_01178 6.4e-235 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
HAMMFLPH_01179 1.07e-35 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
HAMMFLPH_01180 2.67e-38 yjzB - - - - - - -
HAMMFLPH_01181 1.61e-221 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HAMMFLPH_01182 3.06e-302 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HAMMFLPH_01183 9.48e-193 yjaZ - - O - - - Zn-dependent protease
HAMMFLPH_01184 6.15e-234 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HAMMFLPH_01185 2.07e-237 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HAMMFLPH_01186 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
HAMMFLPH_01187 1.04e-219 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HAMMFLPH_01188 1.03e-208 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HAMMFLPH_01189 3.18e-190 yjbA - - S - - - Belongs to the UPF0736 family
HAMMFLPH_01190 6.15e-235 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
HAMMFLPH_01191 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HAMMFLPH_01192 1.03e-212 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HAMMFLPH_01193 7.55e-212 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HAMMFLPH_01194 1.37e-249 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HAMMFLPH_01195 4.43e-220 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HAMMFLPH_01196 3.98e-248 yjbB - - EGP - - - Major Facilitator Superfamily
HAMMFLPH_01197 2.65e-133 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HAMMFLPH_01198 3.51e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HAMMFLPH_01199 7.1e-144 yjbE - - P - - - Integral membrane protein TerC family
HAMMFLPH_01200 6.89e-151 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HAMMFLPH_01201 1.31e-283 coiA - - S ko:K06198 - ko00000 Competence protein
HAMMFLPH_01202 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
HAMMFLPH_01203 2.68e-28 - - - - - - - -
HAMMFLPH_01205 1.32e-218 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
HAMMFLPH_01206 8.58e-94 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
HAMMFLPH_01207 3.42e-127 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HAMMFLPH_01208 5.15e-130 yjbK - - S - - - protein conserved in bacteria
HAMMFLPH_01209 1.87e-81 yjbL - - S - - - Belongs to the UPF0738 family
HAMMFLPH_01210 5.06e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
HAMMFLPH_01211 2.94e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HAMMFLPH_01212 9.4e-206 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
HAMMFLPH_01213 8.09e-181 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
HAMMFLPH_01214 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HAMMFLPH_01215 5.7e-177 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HAMMFLPH_01216 4.01e-139 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
HAMMFLPH_01217 1.14e-277 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
HAMMFLPH_01218 5.35e-42 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 thiamine diphosphate biosynthetic process
HAMMFLPH_01219 6.78e-174 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HAMMFLPH_01220 1.52e-238 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HAMMFLPH_01221 8.38e-192 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HAMMFLPH_01222 1.23e-182 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
HAMMFLPH_01223 2.32e-107 yjbX - - S - - - Spore coat protein
HAMMFLPH_01224 4.57e-108 cotZ - - S ko:K06344 - ko00000 Spore coat protein
HAMMFLPH_01225 3.12e-124 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
HAMMFLPH_01226 3.55e-110 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
HAMMFLPH_01227 1.08e-54 cotW - - - ko:K06341 - ko00000 -
HAMMFLPH_01228 1.44e-72 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
HAMMFLPH_01229 3.03e-76 yjcA - - S - - - Protein of unknown function (DUF1360)
HAMMFLPH_01232 1.88e-52 spoVIF - - S - - - Stage VI sporulation protein F
HAMMFLPH_01233 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
HAMMFLPH_01234 6.31e-51 - - - - - - - -
HAMMFLPH_01235 7.75e-94 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HAMMFLPH_01236 1.2e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
HAMMFLPH_01237 1.63e-178 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
HAMMFLPH_01238 1.98e-273 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HAMMFLPH_01239 6.4e-281 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HAMMFLPH_01240 2.13e-129 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
HAMMFLPH_01241 2.58e-274 yjcL - - S - - - Protein of unknown function (DUF819)
HAMMFLPH_01244 3.75e-269 - - - S - - - Putative amidase domain
HAMMFLPH_01245 1.52e-68 yjcN - - - - - - -
HAMMFLPH_01248 2.24e-106 - - - L - - - Transposase
HAMMFLPH_01249 5.68e-100 yjcP - - - - - - -
HAMMFLPH_01250 1.01e-65 - - - S - - - YjcQ protein
HAMMFLPH_01251 3.29e-121 yqaS - - L - - - DNA packaging
HAMMFLPH_01252 3.8e-63 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
HAMMFLPH_01253 3.42e-181 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
HAMMFLPH_01254 0.000759 - - - - - - - -
HAMMFLPH_01255 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
HAMMFLPH_01256 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HAMMFLPH_01257 6.2e-241 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
HAMMFLPH_01258 4.79e-78 yjdF3 - - S - - - Protein of unknown function (DUF2992)
HAMMFLPH_01259 1.36e-121 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HAMMFLPH_01261 1.01e-105 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HAMMFLPH_01262 6.12e-40 - - - S - - - Domain of unknown function (DUF4177)
HAMMFLPH_01263 2.31e-69 yjdJ - - S - - - Domain of unknown function (DUF4306)
HAMMFLPH_01264 5.31e-224 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HAMMFLPH_01266 0.0 yjeA 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
HAMMFLPH_01267 2.22e-108 - - - S - - - Protein of unknown function (DUF2690)
HAMMFLPH_01268 1.95e-30 yjfB - - S - - - Putative motility protein
HAMMFLPH_01269 3.24e-219 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
HAMMFLPH_01270 1.38e-59 yjgA - - T - - - Protein of unknown function (DUF2809)
HAMMFLPH_01271 1.22e-133 yjgB - - S - - - Domain of unknown function (DUF4309)
HAMMFLPH_01272 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
HAMMFLPH_01273 1.6e-122 yjgD - - S - - - Protein of unknown function (DUF1641)
HAMMFLPH_01275 1.91e-149 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
HAMMFLPH_01277 1.48e-289 yjiB 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
HAMMFLPH_01278 8.74e-280 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HAMMFLPH_01279 1.11e-41 - - - - - - - -
HAMMFLPH_01280 8.69e-189 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
HAMMFLPH_01281 9.04e-156 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
HAMMFLPH_01282 2.79e-175 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HAMMFLPH_01283 1.09e-225 yjlA - - EG - - - Putative multidrug resistance efflux transporter
HAMMFLPH_01284 8.91e-121 yjlB - - S - - - Cupin domain
HAMMFLPH_01285 1.39e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
HAMMFLPH_01286 2.15e-280 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HAMMFLPH_01287 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
HAMMFLPH_01288 6.34e-316 - - - G ko:K03292 - ko00000 symporter YjmB
HAMMFLPH_01289 2.02e-248 allD 1.1.1.350 - C ko:K00073 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000 Belongs to the LDH2 MDH2 oxidoreductase family
HAMMFLPH_01290 1.6e-246 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
HAMMFLPH_01291 1.66e-274 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
HAMMFLPH_01292 1.34e-196 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HAMMFLPH_01293 1.37e-289 exuT - - G ko:K03535,ko:K08191 - ko00000,ko02000 Sugar (and other) transporter
HAMMFLPH_01294 6.95e-238 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
HAMMFLPH_01295 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
HAMMFLPH_01296 0.0 uxaA 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
HAMMFLPH_01297 1.59e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
HAMMFLPH_01298 4.87e-106 yjoA - - S - - - DinB family
HAMMFLPH_01299 6.08e-314 VCP - - O - - - AAA domain (dynein-related subfamily)
HAMMFLPH_01300 1.6e-272 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
HAMMFLPH_01302 1.79e-55 - - - S - - - YCII-related domain
HAMMFLPH_01303 1.37e-220 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
HAMMFLPH_01304 3.31e-81 yjqA - - S - - - Bacterial PH domain
HAMMFLPH_01305 1.47e-143 yjqB - - S - - - Pfam:DUF867
HAMMFLPH_01306 4.54e-204 yjqC - - P ko:K07217 - ko00000 Catalase
HAMMFLPH_01307 1.53e-144 xkdA - - E - - - IrrE N-terminal-like domain
HAMMFLPH_01308 2.01e-74 xre - - K - - - Helix-turn-helix XRE-family like proteins
HAMMFLPH_01310 3.73e-203 xkdB - - K - - - sequence-specific DNA binding
HAMMFLPH_01311 7.48e-153 xkdC - - L - - - Bacterial dnaA protein
HAMMFLPH_01315 5.95e-112 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HAMMFLPH_01316 1.18e-179 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
HAMMFLPH_01317 0.0 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
HAMMFLPH_01318 0.0 yqbA - - S - - - portal protein
HAMMFLPH_01319 9.88e-177 xkdF3 - - L - - - Putative phage serine protease XkdF
HAMMFLPH_01320 3.91e-217 xkdG - - S - - - Phage capsid family
HAMMFLPH_01321 2.06e-85 yqbG - - S - - - Protein of unknown function (DUF3199)
HAMMFLPH_01322 1.05e-85 yqbH - - S - - - Domain of unknown function (DUF3599)
HAMMFLPH_01323 5.84e-115 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
HAMMFLPH_01324 2.87e-101 xkdJ - - - - - - -
HAMMFLPH_01325 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
HAMMFLPH_01326 6.01e-99 xkdM - - S - - - Phage tail tube protein
HAMMFLPH_01327 3.34e-101 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
HAMMFLPH_01328 0.0 xkdO - - L - - - Transglycosylase SLT domain
HAMMFLPH_01329 1.77e-158 xkdP - - S - - - Lysin motif
HAMMFLPH_01330 2.31e-232 xkdQ - - G - - - NLP P60 protein
HAMMFLPH_01331 4.32e-53 xkdR - - S - - - Protein of unknown function (DUF2577)
HAMMFLPH_01332 1.97e-92 xkdS - - S - - - Protein of unknown function (DUF2634)
HAMMFLPH_01333 7.59e-245 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HAMMFLPH_01334 9.63e-136 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
HAMMFLPH_01335 4.43e-56 - - - - - - - -
HAMMFLPH_01336 0.0 - - - - - - - -
HAMMFLPH_01337 8.68e-74 xkdW - - S - - - XkdW protein
HAMMFLPH_01338 9.34e-33 xkdX - - - - - - -
HAMMFLPH_01339 1.51e-198 xepA - - - - - - -
HAMMFLPH_01340 7.71e-52 xhlA - - S - - - Haemolysin XhlA
HAMMFLPH_01341 8.12e-53 xhlB - - S - - - SPP1 phage holin
HAMMFLPH_01342 5.76e-212 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
HAMMFLPH_01343 1.78e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
HAMMFLPH_01344 1.19e-175 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
HAMMFLPH_01345 1.54e-225 pit - - P ko:K03306 - ko00000 phosphate transporter
HAMMFLPH_01346 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
HAMMFLPH_01347 7.7e-311 steT - - E ko:K03294 - ko00000 amino acid
HAMMFLPH_01348 3.43e-234 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
HAMMFLPH_01350 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HAMMFLPH_01351 1.34e-230 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
HAMMFLPH_01353 6.72e-288 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HAMMFLPH_01354 1.54e-183 proG 1.5.1.2 - E ko:K00286,ko:K02239 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko02044 Pyrroline-5-carboxylate reductase
HAMMFLPH_01355 2.42e-197 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
HAMMFLPH_01356 9.7e-204 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HAMMFLPH_01357 6.35e-226 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HAMMFLPH_01358 6.22e-242 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HAMMFLPH_01359 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HAMMFLPH_01361 4.26e-228 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
HAMMFLPH_01362 1.24e-259 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
HAMMFLPH_01363 2.56e-219 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HAMMFLPH_01364 1.77e-238 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HAMMFLPH_01365 9.83e-262 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
HAMMFLPH_01366 4.37e-206 ykgA - - E - - - Amidinotransferase
HAMMFLPH_01367 3.82e-120 ykhA - - I - - - Acyl-CoA hydrolase
HAMMFLPH_01368 2.65e-289 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HAMMFLPH_01369 5.85e-13 - - - - - - - -
HAMMFLPH_01370 4.81e-168 ykjA - - S - - - Protein of unknown function (DUF421)
HAMMFLPH_01371 1.57e-128 ykkA - - S - - - Protein of unknown function (DUF664)
HAMMFLPH_01372 3.59e-128 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HAMMFLPH_01373 1.27e-72 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
HAMMFLPH_01374 2.86e-68 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
HAMMFLPH_01375 5.81e-218 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HAMMFLPH_01376 3.16e-257 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HAMMFLPH_01377 3.38e-291 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HAMMFLPH_01378 2.39e-93 ohrA - - O - - - Organic hydroperoxide resistance protein
HAMMFLPH_01379 1.21e-98 ohrR - - K - - - COG1846 Transcriptional regulators
HAMMFLPH_01380 8.15e-94 ohrB - - O - - - Organic hydroperoxide resistance protein
HAMMFLPH_01382 5.67e-115 guaD 3.5.4.3 - FJ ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 COG0590 Cytosine adenosine deaminases
HAMMFLPH_01383 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HAMMFLPH_01384 3.66e-226 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HAMMFLPH_01385 3.99e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HAMMFLPH_01386 3.8e-175 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
HAMMFLPH_01387 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HAMMFLPH_01388 1.39e-127 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
HAMMFLPH_01389 7.28e-144 ykoF - - S - - - YKOF-related Family
HAMMFLPH_01390 1.28e-160 ykoG - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HAMMFLPH_01391 8.05e-312 ykoH - - T - - - Histidine kinase
HAMMFLPH_01392 3.35e-146 ykoI - - S - - - Peptidase propeptide and YPEB domain
HAMMFLPH_01393 2.24e-112 ykoJ - - S - - - Peptidase propeptide and YPEB domain
HAMMFLPH_01394 1.45e-08 - - - - - - - -
HAMMFLPH_01396 9.86e-300 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
HAMMFLPH_01397 1.49e-70 tnrA - - K - - - transcriptional
HAMMFLPH_01398 1.63e-25 - - - - - - - -
HAMMFLPH_01399 3.04e-36 ykoL - - - - - - -
HAMMFLPH_01400 9.83e-106 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
HAMMFLPH_01401 1.19e-281 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
HAMMFLPH_01402 2.48e-129 ykoP - - G - - - polysaccharide deacetylase
HAMMFLPH_01403 4.35e-198 ykoQ - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
HAMMFLPH_01404 0.0 ykoS - - - - - - -
HAMMFLPH_01405 5.72e-239 ykoT - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
HAMMFLPH_01406 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
HAMMFLPH_01407 7.55e-206 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HAMMFLPH_01408 0.0 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
HAMMFLPH_01409 4.48e-153 ykoX - - S - - - membrane-associated protein
HAMMFLPH_01410 4.63e-227 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HAMMFLPH_01411 1.8e-167 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HAMMFLPH_01412 9.33e-219 rsgI - - S - - - Anti-sigma factor N-terminus
HAMMFLPH_01413 1.4e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
HAMMFLPH_01414 7.68e-160 ykrK - - S - - - Domain of unknown function (DUF1836)
HAMMFLPH_01415 3.4e-200 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
HAMMFLPH_01416 1.82e-310 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
HAMMFLPH_01418 8.33e-31 ykzE - - - - - - -
HAMMFLPH_01419 3.34e-244 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
HAMMFLPH_01420 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HAMMFLPH_01421 2.76e-115 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HAMMFLPH_01423 1.62e-253 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HAMMFLPH_01424 2.47e-293 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HAMMFLPH_01425 1.99e-193 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HAMMFLPH_01426 4.81e-296 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HAMMFLPH_01427 3.39e-295 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
HAMMFLPH_01428 1.07e-176 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
HAMMFLPH_01429 4.52e-147 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
HAMMFLPH_01430 1.5e-123 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HAMMFLPH_01431 8.82e-68 - - - S - - - Protein of unknown function (DUF1232)
HAMMFLPH_01433 5.84e-95 eag - - - - - - -
HAMMFLPH_01434 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
HAMMFLPH_01435 5.17e-99 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
HAMMFLPH_01436 4.91e-170 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
HAMMFLPH_01437 3.23e-178 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
HAMMFLPH_01438 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
HAMMFLPH_01439 4.26e-230 ykvI - - S - - - membrane
HAMMFLPH_01440 1.11e-161 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HAMMFLPH_01441 6.96e-105 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
HAMMFLPH_01442 3.56e-179 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HAMMFLPH_01443 2.36e-125 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HAMMFLPH_01444 2.8e-81 ykvN - - K - - - Transcriptional regulator
HAMMFLPH_01445 9.35e-173 ykvO - - IQ - - - Enoyl-(Acyl carrier protein) reductase
HAMMFLPH_01446 2.69e-275 - - - M - - - Glycosyl transferases group 1
HAMMFLPH_01447 1.85e-48 - 3.5.1.104 - M ko:K22278 - ko00000,ko01000 LysM domain
HAMMFLPH_01448 2.5e-169 - - - G - - - Glycosyl hydrolases family 18
HAMMFLPH_01449 2.67e-62 ykvR - - S - - - Protein of unknown function (DUF3219)
HAMMFLPH_01450 5.43e-35 ykvS - - S - - - protein conserved in bacteria
HAMMFLPH_01451 2.6e-39 - - - - - - - -
HAMMFLPH_01452 9.09e-142 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
HAMMFLPH_01453 1.12e-302 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HAMMFLPH_01454 5.79e-117 stoA - - CO - - - thiol-disulfide
HAMMFLPH_01455 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
HAMMFLPH_01456 3.99e-09 - - - - - - - -
HAMMFLPH_01457 7.85e-266 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
HAMMFLPH_01459 3.28e-230 ykvZ - - K - - - Transcriptional regulator
HAMMFLPH_01461 3.41e-168 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
HAMMFLPH_01462 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HAMMFLPH_01463 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
HAMMFLPH_01464 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HAMMFLPH_01465 1.54e-51 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
HAMMFLPH_01466 2.13e-257 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
HAMMFLPH_01467 5.49e-170 ykwB - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HAMMFLPH_01468 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HAMMFLPH_01469 1.4e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HAMMFLPH_01470 5.36e-172 ykwD - - J - - - protein with SCP PR1 domains
HAMMFLPH_01471 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HAMMFLPH_01472 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HAMMFLPH_01473 5.32e-286 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HAMMFLPH_01474 1.05e-22 - - - - - - - -
HAMMFLPH_01475 4.24e-217 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
HAMMFLPH_01476 3.71e-110 ykyB - - S - - - YkyB-like protein
HAMMFLPH_01477 8.89e-306 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
HAMMFLPH_01478 7.1e-116 ykuD - - S - - - protein conserved in bacteria
HAMMFLPH_01479 3.48e-212 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
HAMMFLPH_01480 1.83e-182 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HAMMFLPH_01481 0.0 ybfG - - M - - - Putative peptidoglycan binding domain
HAMMFLPH_01482 1.52e-120 - - - M - - - Peptidoglycan-binding domain 1 protein
HAMMFLPH_01484 1.76e-298 ykuI - - T - - - Diguanylate phosphodiesterase
HAMMFLPH_01485 5.16e-50 ykuJ - - S - - - protein conserved in bacteria
HAMMFLPH_01486 6.44e-122 - - - S ko:K09776 - ko00000 Ribonuclease H-like
HAMMFLPH_01487 7.83e-38 ykzF - - S - - - Antirepressor AbbA
HAMMFLPH_01488 5.15e-100 ykuL - - S - - - CBS domain
HAMMFLPH_01489 6.52e-216 ccpC - - K - - - Transcriptional regulator
HAMMFLPH_01490 7.72e-114 - - - C ko:K03839 - ko00000 Flavodoxin domain
HAMMFLPH_01491 1.33e-226 ykuO - - - - - - -
HAMMFLPH_01492 1.3e-104 fld - - C ko:K03839 - ko00000 Flavodoxin
HAMMFLPH_01493 1.31e-125 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HAMMFLPH_01494 7.99e-276 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HAMMFLPH_01495 7.23e-51 ykuS - - S - - - Belongs to the UPF0180 family
HAMMFLPH_01496 4.1e-181 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
HAMMFLPH_01497 9.78e-130 ykuU - - O - - - Alkyl hydroperoxide reductase
HAMMFLPH_01498 6.25e-106 ykuV - - CO - - - thiol-disulfide
HAMMFLPH_01499 4.71e-122 rok - - K - - - Repressor of ComK
HAMMFLPH_01500 1.47e-201 yknT - - - ko:K06437 - ko00000 -
HAMMFLPH_01501 9.21e-142 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HAMMFLPH_01502 6.5e-246 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HAMMFLPH_01503 1.05e-313 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
HAMMFLPH_01504 3.44e-122 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
HAMMFLPH_01505 6.61e-110 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
HAMMFLPH_01506 6.92e-45 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HAMMFLPH_01507 0.0 yknU - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HAMMFLPH_01508 0.0 yknV - - V ko:K02021,ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HAMMFLPH_01509 1.6e-151 yknW - - S - - - Yip1 domain
HAMMFLPH_01510 4.93e-235 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HAMMFLPH_01511 6.1e-160 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HAMMFLPH_01512 2.1e-269 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
HAMMFLPH_01513 1.49e-175 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
HAMMFLPH_01514 9.99e-216 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
HAMMFLPH_01515 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HAMMFLPH_01516 1.72e-134 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HAMMFLPH_01517 5.43e-52 ykoA - - - - - - -
HAMMFLPH_01518 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HAMMFLPH_01519 2.99e-217 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HAMMFLPH_01520 2.07e-303 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
HAMMFLPH_01521 1.09e-18 - - - S - - - Uncharacterized protein YkpC
HAMMFLPH_01522 6.17e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
HAMMFLPH_01523 2.63e-58 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
HAMMFLPH_01524 4.59e-307 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
HAMMFLPH_01525 9.21e-208 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
HAMMFLPH_01526 1.68e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
HAMMFLPH_01527 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HAMMFLPH_01528 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HAMMFLPH_01529 8.98e-42 ykzG - - S - - - Belongs to the UPF0356 family
HAMMFLPH_01530 2.03e-187 ykrA - - S - - - hydrolases of the HAD superfamily
HAMMFLPH_01531 3.96e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HAMMFLPH_01532 2.24e-19 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
HAMMFLPH_01533 6.82e-149 ykyA - - L - - - Putative cell-wall binding lipoprotein
HAMMFLPH_01534 1.06e-258 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HAMMFLPH_01535 1.75e-227 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HAMMFLPH_01536 1.47e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HAMMFLPH_01537 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HAMMFLPH_01538 4.55e-83 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
HAMMFLPH_01539 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
HAMMFLPH_01540 1.34e-56 yktA - - S - - - Belongs to the UPF0223 family
HAMMFLPH_01541 1.3e-152 yktB - - S - - - Belongs to the UPF0637 family
HAMMFLPH_01542 4.48e-35 ykzI - - - - - - -
HAMMFLPH_01543 9.48e-195 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
HAMMFLPH_01544 1.48e-100 ykzC - - S - - - Acetyltransferase (GNAT) family
HAMMFLPH_01545 1.28e-223 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HAMMFLPH_01546 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
HAMMFLPH_01547 0.0 ylaA - - - - - - -
HAMMFLPH_01548 1.44e-56 ylaB - - - - - - -
HAMMFLPH_01549 4.51e-118 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HAMMFLPH_01551 1.74e-57 ylaE - - - - - - -
HAMMFLPH_01552 2.21e-30 - - - S - - - Family of unknown function (DUF5325)
HAMMFLPH_01553 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
HAMMFLPH_01554 4.4e-63 ylaH - - S - - - YlaH-like protein
HAMMFLPH_01555 8.92e-44 ylaI - - S - - - protein conserved in bacteria
HAMMFLPH_01556 2.97e-127 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HAMMFLPH_01557 3.76e-316 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
HAMMFLPH_01558 9.32e-112 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HAMMFLPH_01559 4.25e-220 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
HAMMFLPH_01560 6.94e-59 ylaN - - S - - - Belongs to the UPF0358 family
HAMMFLPH_01561 2.57e-273 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
HAMMFLPH_01562 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HAMMFLPH_01563 2.97e-214 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HAMMFLPH_01564 1.7e-208 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HAMMFLPH_01565 5.85e-253 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HAMMFLPH_01566 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HAMMFLPH_01567 1.84e-145 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HAMMFLPH_01568 6.09e-70 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HAMMFLPH_01569 1.04e-214 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
HAMMFLPH_01570 1.61e-81 ylbA - - S - - - YugN-like family
HAMMFLPH_01571 1.08e-97 ylbB - - T - - - COG0517 FOG CBS domain
HAMMFLPH_01572 4.58e-258 ylbC - - S - - - protein with SCP PR1 domains
HAMMFLPH_01573 3.24e-89 ylbD - - S - - - Putative coat protein
HAMMFLPH_01574 1.73e-48 ylbE - - S - - - YlbE-like protein
HAMMFLPH_01575 2.34e-97 ylbF - - S - - - Belongs to the UPF0342 family
HAMMFLPH_01576 4.36e-52 ylbG - - S - - - UPF0298 protein
HAMMFLPH_01577 2.12e-126 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
HAMMFLPH_01578 3.8e-111 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HAMMFLPH_01579 2.73e-282 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
HAMMFLPH_01580 2.56e-176 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
HAMMFLPH_01581 7.81e-239 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
HAMMFLPH_01582 5.94e-301 ylbM - - S - - - Belongs to the UPF0348 family
HAMMFLPH_01584 1.7e-117 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
HAMMFLPH_01585 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
HAMMFLPH_01586 5.75e-108 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HAMMFLPH_01587 3.26e-116 ylbP - - K - - - n-acetyltransferase
HAMMFLPH_01588 1.66e-216 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HAMMFLPH_01589 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HAMMFLPH_01590 9.82e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
HAMMFLPH_01591 4.97e-220 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HAMMFLPH_01592 3.42e-68 ftsL - - D - - - Essential cell division protein
HAMMFLPH_01593 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HAMMFLPH_01594 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
HAMMFLPH_01595 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HAMMFLPH_01596 9.59e-220 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HAMMFLPH_01597 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HAMMFLPH_01598 6.64e-237 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
HAMMFLPH_01599 9.42e-258 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HAMMFLPH_01600 7.54e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
HAMMFLPH_01601 1.18e-178 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HAMMFLPH_01602 3.45e-146 ylxW - - S - - - protein conserved in bacteria
HAMMFLPH_01603 1.06e-132 ylxX - - S - - - protein conserved in bacteria
HAMMFLPH_01604 5.37e-76 sbp - - S - - - small basic protein
HAMMFLPH_01605 4.88e-299 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HAMMFLPH_01606 1.84e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HAMMFLPH_01607 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
HAMMFLPH_01608 1.06e-220 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HAMMFLPH_01609 1.48e-160 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HAMMFLPH_01610 7.99e-180 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HAMMFLPH_01611 3.84e-189 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HAMMFLPH_01612 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
HAMMFLPH_01613 3.58e-51 ylmC - - S - - - sporulation protein
HAMMFLPH_01614 5.53e-205 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
HAMMFLPH_01615 3.15e-162 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HAMMFLPH_01616 5.44e-88 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HAMMFLPH_01617 1.22e-53 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
HAMMFLPH_01618 3.67e-179 ylmH - - S - - - conserved protein, contains S4-like domain
HAMMFLPH_01619 6.44e-100 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
HAMMFLPH_01620 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HAMMFLPH_01621 1.58e-83 ylyA - - T - - - COG1734 DnaK suppressor protein
HAMMFLPH_01622 2.71e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HAMMFLPH_01623 3.52e-225 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HAMMFLPH_01624 4.45e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HAMMFLPH_01625 2.24e-295 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
HAMMFLPH_01626 4.4e-215 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
HAMMFLPH_01627 0.0 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HAMMFLPH_01628 1.31e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
HAMMFLPH_01629 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
HAMMFLPH_01630 3.84e-185 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HAMMFLPH_01631 1.33e-224 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HAMMFLPH_01632 6.56e-164 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HAMMFLPH_01633 3.8e-150 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HAMMFLPH_01635 3.58e-183 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
HAMMFLPH_01636 7.32e-230 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
HAMMFLPH_01637 2.62e-285 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
HAMMFLPH_01638 5.56e-142 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
HAMMFLPH_01639 1.24e-186 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
HAMMFLPH_01640 4.33e-189 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
HAMMFLPH_01641 2.28e-108 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
HAMMFLPH_01642 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
HAMMFLPH_01643 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
HAMMFLPH_01644 8.41e-202 yloC - - S - - - stress-induced protein
HAMMFLPH_01645 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
HAMMFLPH_01646 5.73e-143 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
HAMMFLPH_01647 6.21e-39 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HAMMFLPH_01648 4.59e-289 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HAMMFLPH_01649 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HAMMFLPH_01650 2.89e-110 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HAMMFLPH_01651 2.21e-226 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HAMMFLPH_01652 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HAMMFLPH_01653 3.73e-264 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HAMMFLPH_01654 3.03e-181 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
HAMMFLPH_01655 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
HAMMFLPH_01656 1.37e-215 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HAMMFLPH_01657 4.68e-153 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
HAMMFLPH_01658 2.83e-157 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
HAMMFLPH_01659 7.06e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
HAMMFLPH_01660 3.65e-78 yloU - - S - - - protein conserved in bacteria
HAMMFLPH_01661 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
HAMMFLPH_01662 1.45e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
HAMMFLPH_01663 1.19e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
HAMMFLPH_01664 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HAMMFLPH_01665 6.22e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HAMMFLPH_01666 8.33e-230 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HAMMFLPH_01667 1.31e-218 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
HAMMFLPH_01668 3.5e-167 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
HAMMFLPH_01669 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
HAMMFLPH_01670 2.12e-174 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HAMMFLPH_01671 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
HAMMFLPH_01672 3.38e-227 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HAMMFLPH_01673 1.67e-114 - - - - - - - -
HAMMFLPH_01674 5.64e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HAMMFLPH_01675 9.7e-309 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HAMMFLPH_01676 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
HAMMFLPH_01677 2.95e-50 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
HAMMFLPH_01678 5.89e-81 ylqD - - S - - - YlqD protein
HAMMFLPH_01679 1.84e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HAMMFLPH_01680 2.41e-177 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
HAMMFLPH_01681 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HAMMFLPH_01682 1.2e-201 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HAMMFLPH_01683 2.04e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HAMMFLPH_01684 0.0 ylqG - - - - - - -
HAMMFLPH_01685 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
HAMMFLPH_01686 6.77e-269 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HAMMFLPH_01687 1.53e-213 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HAMMFLPH_01688 6.53e-218 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
HAMMFLPH_01689 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HAMMFLPH_01690 5.45e-314 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HAMMFLPH_01691 1.13e-217 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
HAMMFLPH_01692 3.01e-120 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HAMMFLPH_01693 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HAMMFLPH_01694 1.95e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HAMMFLPH_01695 1.62e-83 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HAMMFLPH_01696 7.54e-99 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
HAMMFLPH_01697 5.5e-53 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
HAMMFLPH_01698 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
HAMMFLPH_01699 6.08e-230 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HAMMFLPH_01700 1.92e-144 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
HAMMFLPH_01701 2.11e-308 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HAMMFLPH_01702 1.79e-91 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
HAMMFLPH_01703 5.08e-84 ylxF - - S - - - MgtE intracellular N domain
HAMMFLPH_01704 2.31e-314 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
HAMMFLPH_01705 2.81e-96 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
HAMMFLPH_01706 1.09e-179 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
HAMMFLPH_01707 5.59e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
HAMMFLPH_01708 6.61e-231 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HAMMFLPH_01709 1.38e-253 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HAMMFLPH_01710 2.12e-77 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
HAMMFLPH_01711 5.54e-137 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
HAMMFLPH_01712 1.21e-141 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
HAMMFLPH_01713 5.23e-50 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
HAMMFLPH_01714 1.47e-170 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
HAMMFLPH_01715 2.74e-244 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HAMMFLPH_01716 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HAMMFLPH_01717 5.65e-256 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
HAMMFLPH_01718 1.09e-200 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
HAMMFLPH_01719 1.81e-252 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HAMMFLPH_01720 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
HAMMFLPH_01721 1.56e-103 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
HAMMFLPH_01722 5.06e-144 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HAMMFLPH_01723 3.34e-112 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HAMMFLPH_01724 6.57e-176 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HAMMFLPH_01725 6.91e-101 ylxL - - - - - - -
HAMMFLPH_01726 1.49e-168 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
HAMMFLPH_01727 9.82e-202 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HAMMFLPH_01728 5.82e-163 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
HAMMFLPH_01729 9.6e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HAMMFLPH_01730 3.84e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HAMMFLPH_01731 5.77e-179 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
HAMMFLPH_01732 1.39e-276 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HAMMFLPH_01733 6.84e-294 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
HAMMFLPH_01734 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HAMMFLPH_01735 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HAMMFLPH_01736 1.34e-104 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
HAMMFLPH_01737 5.49e-261 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
HAMMFLPH_01738 2.01e-57 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
HAMMFLPH_01739 6.16e-63 ylxQ - - J - - - ribosomal protein
HAMMFLPH_01740 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HAMMFLPH_01741 7.83e-60 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
HAMMFLPH_01742 3.29e-75 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HAMMFLPH_01743 5.18e-221 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HAMMFLPH_01744 1.63e-232 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
HAMMFLPH_01745 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HAMMFLPH_01746 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HAMMFLPH_01747 1.29e-235 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
HAMMFLPH_01748 1.62e-295 mlpA - - S - - - Belongs to the peptidase M16 family
HAMMFLPH_01749 1.53e-56 ymxH - - S - - - YlmC YmxH family
HAMMFLPH_01750 5.3e-208 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
HAMMFLPH_01751 9.94e-142 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HAMMFLPH_01752 1.66e-247 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HAMMFLPH_01753 1.2e-283 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HAMMFLPH_01754 1.57e-201 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HAMMFLPH_01755 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HAMMFLPH_01756 5.01e-171 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
HAMMFLPH_01757 4.94e-44 - - - S - - - YlzJ-like protein
HAMMFLPH_01758 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
HAMMFLPH_01759 1.28e-171 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
HAMMFLPH_01760 2.08e-267 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HAMMFLPH_01761 3.45e-301 albE - - S - - - Peptidase M16
HAMMFLPH_01762 2.37e-309 ymfH - - S - - - zinc protease
HAMMFLPH_01763 6.33e-168 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
HAMMFLPH_01764 5.13e-55 ymfJ - - S - - - Protein of unknown function (DUF3243)
HAMMFLPH_01765 3.91e-183 ymfK - - S - - - Protein of unknown function (DUF3388)
HAMMFLPH_01766 3.05e-177 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
HAMMFLPH_01767 3.34e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HAMMFLPH_01768 3.71e-300 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
HAMMFLPH_01769 4.7e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HAMMFLPH_01770 8.43e-282 pbpX - - V - - - Beta-lactamase
HAMMFLPH_01771 4.25e-306 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
HAMMFLPH_01772 6.18e-195 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
HAMMFLPH_01773 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
HAMMFLPH_01774 3.02e-255 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
HAMMFLPH_01775 1.02e-278 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HAMMFLPH_01776 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HAMMFLPH_01777 1.27e-89 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
HAMMFLPH_01778 1.74e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
HAMMFLPH_01779 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HAMMFLPH_01780 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HAMMFLPH_01781 7.19e-93 - - - S - - - Regulatory protein YrvL
HAMMFLPH_01783 1.38e-127 ymcC - - S - - - Membrane
HAMMFLPH_01784 2.94e-141 pksA - - K - - - Transcriptional regulator
HAMMFLPH_01785 4.02e-167 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
HAMMFLPH_01786 1.31e-208 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
HAMMFLPH_01787 2.08e-239 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
HAMMFLPH_01788 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
HAMMFLPH_01789 5.46e-51 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
HAMMFLPH_01790 5.31e-304 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HAMMFLPH_01791 9.7e-314 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
HAMMFLPH_01792 2.48e-184 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
HAMMFLPH_01793 2.69e-177 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
HAMMFLPH_01794 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
HAMMFLPH_01795 0.0 - - - Q ko:K13612 - ko00000,ko01004,ko01008 Polyketide synthase of type I
HAMMFLPH_01796 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
HAMMFLPH_01797 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
HAMMFLPH_01798 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
HAMMFLPH_01799 2.49e-297 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
HAMMFLPH_01800 2.8e-81 ymzB - - - - - - -
HAMMFLPH_01801 4.8e-210 - - - S - - - Metallo-beta-lactamase superfamily
HAMMFLPH_01802 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
HAMMFLPH_01803 3.96e-163 ymaC - - S - - - Replication protein
HAMMFLPH_01804 1.03e-105 ymaD - - O - - - redox protein, regulator of disulfide bond formation
HAMMFLPH_01805 1.57e-73 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 COG2076 Membrane transporters of cations and cationic drugs
HAMMFLPH_01806 1.21e-67 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
HAMMFLPH_01808 5.41e-76 ymaF - - S - - - YmaF family
HAMMFLPH_01809 9.69e-224 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HAMMFLPH_01810 1.28e-45 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HAMMFLPH_01811 8.07e-32 - - - - - - - -
HAMMFLPH_01812 1.2e-30 ymzA - - - - - - -
HAMMFLPH_01813 5.01e-66 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
HAMMFLPH_01814 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HAMMFLPH_01815 1.65e-243 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HAMMFLPH_01816 2.24e-141 - - - - - - - -
HAMMFLPH_01817 1.72e-151 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
HAMMFLPH_01818 2.29e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
HAMMFLPH_01819 4.47e-294 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HAMMFLPH_01820 5.82e-311 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HAMMFLPH_01821 9.94e-90 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
HAMMFLPH_01822 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
HAMMFLPH_01823 1.57e-170 int - - L - - - Belongs to the 'phage' integrase family
HAMMFLPH_01824 6.02e-55 - - - E - - - Zn peptidase
HAMMFLPH_01825 1.14e-33 - - - K - - - Helix-turn-helix XRE-family like proteins
HAMMFLPH_01827 1.48e-31 - - - - - - - -
HAMMFLPH_01829 9.02e-105 - - - S ko:K07741 - ko00000 Phage regulatory protein Rha (Phage_pRha)
HAMMFLPH_01832 2.28e-108 - - - L - - - DnaD domain protein
HAMMFLPH_01833 9.77e-18 - - - S - - - Loader and inhibitor of phage G40P
HAMMFLPH_01834 1.33e-211 - 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 replicative DNA helicase
HAMMFLPH_01835 5.34e-31 - - - - - - - -
HAMMFLPH_01836 6.08e-12 - - - S - - - Phage-like element PBSX protein XtrA
HAMMFLPH_01837 0.000611 - - - - - - - -
HAMMFLPH_01838 3.89e-66 - - - M - - - ArpU family transcriptional regulator
HAMMFLPH_01842 6.68e-116 yrdC - - Q - - - Isochorismatase family
HAMMFLPH_01844 2.02e-95 yvgO - - - - - - -
HAMMFLPH_01845 1.48e-102 - - - S - - - Domain of unknown function (DUF4868)
HAMMFLPH_01846 1.63e-56 - - - - - - - -
HAMMFLPH_01847 2.89e-38 - - - - - - - -
HAMMFLPH_01850 6.88e-66 - - - V ko:K07451 - ko00000,ko01000,ko02048 HNH endonuclease
HAMMFLPH_01851 5.19e-102 - - - L - - - phage terminase small subunit
HAMMFLPH_01852 0.0 - - - S - - - Terminase
HAMMFLPH_01854 5.52e-220 - - - S - - - Phage portal protein
HAMMFLPH_01855 5.33e-102 - - - S - - - peptidase activity
HAMMFLPH_01856 1.29e-202 - - - S - - - capsid protein
HAMMFLPH_01857 3.8e-34 - - - - - - - -
HAMMFLPH_01858 6.93e-51 - - - S - - - Phage gp6-like head-tail connector protein
HAMMFLPH_01859 3.02e-51 - - - S - - - Phage head-tail joining protein
HAMMFLPH_01860 9.8e-66 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
HAMMFLPH_01862 5.6e-102 - - - S - - - Phage tail tube protein
HAMMFLPH_01865 0.0 - - - D - - - phage tail tape measure protein
HAMMFLPH_01866 2.06e-143 - - - S - - - Phage tail protein
HAMMFLPH_01867 7.09e-278 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
HAMMFLPH_01868 0.0 - - - S - - - Peptidase_G2, IMC autoproteolytic cleavage domain
HAMMFLPH_01869 3.21e-144 - - - S - - - Domain of unknown function (DUF2479)
HAMMFLPH_01872 6.25e-75 - - - S - - - Bacteriophage holin family
HAMMFLPH_01873 1.07e-160 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
HAMMFLPH_01874 9.44e-85 - - - S - - - Immunity protein 70
HAMMFLPH_01875 2.06e-243 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
HAMMFLPH_01876 3.38e-138 rapK - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
HAMMFLPH_01880 2.95e-14 - - - - - - - -
HAMMFLPH_01881 2.61e-40 - - - - - - - -
HAMMFLPH_01882 7.13e-52 - - - - - - - -
HAMMFLPH_01883 5.4e-105 - - - G - - - regulation of fungal-type cell wall biogenesis
HAMMFLPH_01884 1.97e-186 ynaC - - - - - - -
HAMMFLPH_01885 7.56e-129 ynaD - - J - - - Acetyltransferase (GNAT) domain
HAMMFLPH_01886 1.65e-160 - - - S - - - Domain of unknown function (DUF3885)
HAMMFLPH_01887 1.06e-80 ynaF - - - - - - -
HAMMFLPH_01890 4.32e-110 - - - E - - - phosphoribosylanthranilate isomerase activity
HAMMFLPH_01891 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
HAMMFLPH_01892 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
HAMMFLPH_01893 3.15e-278 xylR - - GK - - - ROK family
HAMMFLPH_01894 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
HAMMFLPH_01895 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
HAMMFLPH_01896 9.1e-148 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
HAMMFLPH_01897 3.64e-313 - - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HAMMFLPH_01898 3.05e-281 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HAMMFLPH_01899 3.44e-110 - - - S - - - Protein of unknown function (DUF2691)
HAMMFLPH_01900 3.01e-102 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
HAMMFLPH_01901 7.54e-22 - - - - - - - -
HAMMFLPH_01904 7.03e-213 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HAMMFLPH_01906 1.55e-172 - - - S - - - Domain of unknown function, YrpD
HAMMFLPH_01909 2.37e-34 tatA - - U ko:K03116,ko:K03117,ko:K03646 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02000,ko02044 protein secretion
HAMMFLPH_01910 8.92e-96 - - - - - - - -
HAMMFLPH_01911 3.12e-104 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
HAMMFLPH_01914 0.0 yndD1 - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
HAMMFLPH_01915 2.38e-251 yndE7 - - U ko:K06311 - ko00000,ko02000 Spore germination
HAMMFLPH_01916 9.64e-290 - - - S ko:K06293,ko:K06312 - ko00000 Spore germination protein
HAMMFLPH_01917 9.15e-199 yndG - - S - - - DoxX-like family
HAMMFLPH_01918 1.26e-151 - - - S - - - Domain of unknown function (DUF4166)
HAMMFLPH_01919 0.0 yndJ - - S - - - YndJ-like protein
HAMMFLPH_01921 1.68e-177 yndL - - S - - - Replication protein
HAMMFLPH_01922 1.32e-96 yndM - - S - - - Protein of unknown function (DUF2512)
HAMMFLPH_01923 4.44e-104 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
HAMMFLPH_01925 7.22e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HAMMFLPH_01926 8.5e-65 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
HAMMFLPH_01927 3.97e-145 yneB - - L - - - resolvase
HAMMFLPH_01928 1.15e-43 ynzC - - S - - - UPF0291 protein
HAMMFLPH_01929 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HAMMFLPH_01930 2.18e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
HAMMFLPH_01931 4.36e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
HAMMFLPH_01932 4.59e-21 ynzD - - S - - - Spo0E like sporulation regulatory protein
HAMMFLPH_01933 4.13e-165 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
HAMMFLPH_01934 7.38e-78 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
HAMMFLPH_01935 2.51e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
HAMMFLPH_01936 2.79e-97 yneK - - S - - - Protein of unknown function (DUF2621)
HAMMFLPH_01937 1.21e-86 cotM - - O ko:K06335 - ko00000 Spore coat protein
HAMMFLPH_01938 5.65e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
HAMMFLPH_01939 3.75e-21 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
HAMMFLPH_01940 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HAMMFLPH_01941 3.74e-120 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HAMMFLPH_01942 9.26e-10 - - - S - - - Fur-regulated basic protein B
HAMMFLPH_01944 6.62e-48 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
HAMMFLPH_01945 1.4e-95 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
HAMMFLPH_01946 1.63e-71 yneQ - - - - - - -
HAMMFLPH_01947 8.97e-65 yneR - - S - - - Belongs to the HesB IscA family
HAMMFLPH_01948 5.48e-122 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HAMMFLPH_01949 1.21e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
HAMMFLPH_01950 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HAMMFLPH_01951 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HAMMFLPH_01952 1.82e-18 - - - - - - - -
HAMMFLPH_01953 1.06e-75 ynfC - - - - - - -
HAMMFLPH_01954 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
HAMMFLPH_01955 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
HAMMFLPH_01957 0.0 ynfF 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
HAMMFLPH_01958 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
HAMMFLPH_01959 1.04e-104 yngA - - S - - - membrane
HAMMFLPH_01960 2.74e-210 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
HAMMFLPH_01961 2.01e-134 yngC - - S - - - membrane-associated protein
HAMMFLPH_01962 4.46e-297 yngD - - S ko:K07097 - ko00000 phosphohydrolase (DHH superfamily)
HAMMFLPH_01963 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HAMMFLPH_01964 1.48e-175 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
HAMMFLPH_01965 7.02e-214 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
HAMMFLPH_01966 1.23e-43 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
HAMMFLPH_01967 0.0 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
HAMMFLPH_01968 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HAMMFLPH_01969 1.31e-268 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
HAMMFLPH_01970 4.3e-41 - - - S - - - Family of unknown function (DUF5367)
HAMMFLPH_01971 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
HAMMFLPH_01972 2.12e-84 yngL - - S - - - Protein of unknown function (DUF1360)
HAMMFLPH_01973 0.0 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
HAMMFLPH_01974 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HAMMFLPH_01975 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HAMMFLPH_01976 0.0 - - - Q ko:K15665 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HAMMFLPH_01977 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HAMMFLPH_01978 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
HAMMFLPH_01979 2.54e-245 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
HAMMFLPH_01980 9.8e-313 yoeA - - V - - - MATE efflux family protein
HAMMFLPH_01981 7.14e-128 yoeB - - S - - - IseA DL-endopeptidase inhibitor
HAMMFLPH_01983 1.14e-124 - - - L - - - Integrase
HAMMFLPH_01984 3.31e-47 yoeD - - G - - - Helix-turn-helix domain
HAMMFLPH_01985 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
HAMMFLPH_01986 1.3e-202 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
HAMMFLPH_01987 7.23e-238 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HAMMFLPH_01988 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HAMMFLPH_01989 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
HAMMFLPH_01990 2.61e-205 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
HAMMFLPH_01991 8.13e-263 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HAMMFLPH_01992 2.72e-185 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HAMMFLPH_01993 5.37e-79 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
HAMMFLPH_01994 7.94e-160 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
HAMMFLPH_01995 8.39e-57 yoxC - - S - - - Bacterial protein of unknown function (DUF948)
HAMMFLPH_01996 1.34e-185 yoxB - - - - - - -
HAMMFLPH_01997 5.91e-125 yoaA 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HAMMFLPH_01998 1.11e-300 yoaB - - EGP - - - the major facilitator superfamily
HAMMFLPH_01999 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
HAMMFLPH_02000 3.41e-243 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HAMMFLPH_02001 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HAMMFLPH_02002 2.08e-44 yoaF - - - - - - -
HAMMFLPH_02004 1.25e-20 - - - - - - - -
HAMMFLPH_02005 8.23e-62 - - - S - - - Protein of unknown function (DUF4025)
HAMMFLPH_02006 0.0 yoaH - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 methyl-accepting chemotaxis protein
HAMMFLPH_02007 0.0 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
HAMMFLPH_02008 2.61e-171 yoaJ - - G ko:K20628 - ko00000 Endoglucanase C-terminal domain subunit and related proteins
HAMMFLPH_02009 1.79e-145 yoaK - - S - - - Membrane
HAMMFLPH_02010 5e-253 - 4.2.2.10 - G ko:K01732 - ko00000,ko01000 Amb_all
HAMMFLPH_02011 5.08e-171 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
HAMMFLPH_02013 1.95e-296 oxdD 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
HAMMFLPH_02015 9.48e-188 yoaP - - K - - - YoaP-like
HAMMFLPH_02016 7.38e-88 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
HAMMFLPH_02017 2.36e-116 - - - - - - - -
HAMMFLPH_02018 3.63e-218 yoaR - - V - - - vancomycin resistance protein
HAMMFLPH_02019 1.6e-98 yoaS - - S - - - Protein of unknown function (DUF2975)
HAMMFLPH_02020 7.38e-50 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
HAMMFLPH_02021 6.92e-192 yoaT - - S - - - Protein of unknown function (DUF817)
HAMMFLPH_02022 6.67e-203 yoaU - - K - - - LysR substrate binding domain
HAMMFLPH_02023 1.11e-202 yoaV - - EG - - - EamA-like transporter family
HAMMFLPH_02024 6.84e-103 yoaW - - - - - - -
HAMMFLPH_02025 3.88e-153 lin0465 - - S - - - DJ-1/PfpI family
HAMMFLPH_02026 9.26e-218 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
HAMMFLPH_02030 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
HAMMFLPH_02031 1.3e-157 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
HAMMFLPH_02032 6.27e-51 - - - S - - - TM2 domain
HAMMFLPH_02033 3.92e-76 - - - K - - - Helix-turn-helix
HAMMFLPH_02035 1.21e-90 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
HAMMFLPH_02036 1.92e-162 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
HAMMFLPH_02037 6.85e-229 - - - - - - - -
HAMMFLPH_02038 1.36e-08 - - - - - - - -
HAMMFLPH_02042 6.23e-267 - - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
HAMMFLPH_02044 6.17e-158 dinB2 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HAMMFLPH_02045 1.52e-79 dinB2 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HAMMFLPH_02046 2.05e-51 - - - S - - - YolD-like protein
HAMMFLPH_02047 2.08e-64 - - - - - - - -
HAMMFLPH_02048 0.0 - - - K - - - Psort location Cytoplasmic, score
HAMMFLPH_02049 3.58e-202 - - - - - - - -
HAMMFLPH_02050 6.69e-112 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
HAMMFLPH_02051 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HAMMFLPH_02052 4.3e-136 yokH - - G - - - SMI1 / KNR4 family
HAMMFLPH_02053 0.0 iaaM 1.4.3.4 - E ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 ko00000,ko00001,ko00002,ko01000 COG1231 Monoamine oxidase
HAMMFLPH_02054 0.0 yobO - - M - - - Pectate lyase superfamily protein
HAMMFLPH_02055 2.21e-72 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
HAMMFLPH_02056 5.23e-175 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
HAMMFLPH_02057 1.29e-183 - - - J - - - FR47-like protein
HAMMFLPH_02058 9.22e-129 yobS - - K - - - Transcriptional regulator
HAMMFLPH_02059 1.34e-169 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
HAMMFLPH_02060 1.55e-114 - - - K - - - Bacterial transcription activator, effector binding domain
HAMMFLPH_02061 2.05e-229 yobV - - K - - - WYL domain
HAMMFLPH_02062 7.69e-123 yobW - - - - - - -
HAMMFLPH_02063 8.12e-69 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
HAMMFLPH_02064 3.28e-157 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HAMMFLPH_02065 3.97e-119 yozB - - S ko:K08976 - ko00000 membrane
HAMMFLPH_02066 4.49e-186 - - - - - - - -
HAMMFLPH_02067 1.32e-122 yocC - - - - - - -
HAMMFLPH_02068 1.21e-243 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
HAMMFLPH_02069 3.99e-258 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
HAMMFLPH_02070 1.22e-252 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HAMMFLPH_02071 4.71e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HAMMFLPH_02072 2.89e-175 yocH - - M - - - COG1388 FOG LysM repeat
HAMMFLPH_02073 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
HAMMFLPH_02074 1.46e-147 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HAMMFLPH_02075 1.42e-107 yocK - - T - - - general stress protein
HAMMFLPH_02076 3.02e-70 yocL - - - - - - -
HAMMFLPH_02077 7.29e-46 - - - - - - - -
HAMMFLPH_02078 6.6e-115 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HAMMFLPH_02079 2.94e-55 yozN - - - - - - -
HAMMFLPH_02080 1.83e-49 yocN - - - - - - -
HAMMFLPH_02081 2.17e-74 yozO - - S - - - Bacterial PH domain
HAMMFLPH_02082 1.91e-42 yozC - - - - - - -
HAMMFLPH_02083 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HAMMFLPH_02084 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
HAMMFLPH_02085 3.35e-212 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
HAMMFLPH_02086 4.35e-300 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HAMMFLPH_02087 3.31e-214 yocS - - S ko:K03453 - ko00000 -transporter
HAMMFLPH_02088 3.16e-265 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HAMMFLPH_02089 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HAMMFLPH_02090 0.0 yojO - - P - - - Von Willebrand factor
HAMMFLPH_02091 1.33e-207 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
HAMMFLPH_02092 3.62e-142 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HAMMFLPH_02093 1.3e-267 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
HAMMFLPH_02094 5.62e-294 yojK - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
HAMMFLPH_02095 3.69e-142 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HAMMFLPH_02097 5.06e-314 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
HAMMFLPH_02098 2.49e-194 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HAMMFLPH_02099 1.84e-161 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
HAMMFLPH_02100 2.32e-79 yojF - - S - - - Protein of unknown function (DUF1806)
HAMMFLPH_02101 1.85e-58 - - - - - - - -
HAMMFLPH_02102 1.21e-209 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
HAMMFLPH_02103 7.43e-107 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
HAMMFLPH_02104 1.95e-14 - - - - - - - -
HAMMFLPH_02105 1.01e-293 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
HAMMFLPH_02106 2.05e-86 iolK - - S - - - tautomerase
HAMMFLPH_02107 1.37e-76 yodB - - K - - - transcriptional
HAMMFLPH_02108 1.92e-140 yodC - - C - - - nitroreductase
HAMMFLPH_02109 1.31e-146 yahD - - S ko:K06999 - ko00000 Carboxylesterase
HAMMFLPH_02110 1.18e-223 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
HAMMFLPH_02111 2.36e-38 - - - S - - - Protein of unknown function (DUF3311)
HAMMFLPH_02112 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HAMMFLPH_02113 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
HAMMFLPH_02114 6.38e-168 yodH - - Q - - - Methyltransferase
HAMMFLPH_02115 2.93e-42 yodI - - - - - - -
HAMMFLPH_02116 1.62e-190 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
HAMMFLPH_02117 1.19e-163 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
HAMMFLPH_02118 2.08e-12 - - - - - - - -
HAMMFLPH_02119 1.17e-71 yodL - - S - - - YodL-like
HAMMFLPH_02120 4.02e-138 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
HAMMFLPH_02121 5.18e-34 yozD - - S - - - YozD-like protein
HAMMFLPH_02123 3.84e-161 yodN - - - - - - -
HAMMFLPH_02124 7.3e-50 yozE - - S - - - Belongs to the UPF0346 family
HAMMFLPH_02125 3.44e-63 yokU - - S - - - YokU-like protein, putative antitoxin
HAMMFLPH_02126 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
HAMMFLPH_02127 9.5e-200 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
HAMMFLPH_02128 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
HAMMFLPH_02129 9.44e-153 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HAMMFLPH_02131 0.0 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HAMMFLPH_02134 2.06e-186 yiiD - - K ko:K06323 - ko00000 acetyltransferase
HAMMFLPH_02135 0.0 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
HAMMFLPH_02136 3.04e-59 cgeC - - - ko:K06321 - ko00000 -
HAMMFLPH_02137 5.57e-86 cgeA - - - ko:K06319 - ko00000 -
HAMMFLPH_02138 2.95e-240 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
HAMMFLPH_02139 4.17e-282 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
HAMMFLPH_02140 1.66e-157 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
HAMMFLPH_02141 3.52e-105 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
HAMMFLPH_02142 8.41e-134 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HAMMFLPH_02143 4.14e-94 ypoP - - K - - - transcriptional
HAMMFLPH_02144 3.49e-290 mepA - - V - - - MATE efflux family protein
HAMMFLPH_02145 2.13e-40 ypmT - - S - - - Uncharacterized ympT
HAMMFLPH_02146 6.8e-129 ypmS - - S - - - protein conserved in bacteria
HAMMFLPH_02147 1.28e-178 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
HAMMFLPH_02148 2.77e-140 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
HAMMFLPH_02149 1.28e-54 ypmP - - S - - - Protein of unknown function (DUF2535)
HAMMFLPH_02150 3.64e-310 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HAMMFLPH_02151 1.4e-236 yplP - - K - - - Transcriptional regulator
HAMMFLPH_02152 8.03e-143 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
HAMMFLPH_02153 1.71e-145 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HAMMFLPH_02154 1.21e-124 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HAMMFLPH_02155 7.27e-203 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HAMMFLPH_02156 8.91e-121 ltrC 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
HAMMFLPH_02157 3.47e-148 ypjP - - S - - - YpjP-like protein
HAMMFLPH_02158 6.15e-187 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
HAMMFLPH_02159 9.69e-99 yphP - - S - - - Belongs to the UPF0403 family
HAMMFLPH_02160 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
HAMMFLPH_02161 8.52e-206 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
HAMMFLPH_02162 2.52e-142 yagB - - S ko:K06950 - ko00000 phosphohydrolase
HAMMFLPH_02163 1.89e-115 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
HAMMFLPH_02164 1.28e-226 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HAMMFLPH_02165 1.28e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
HAMMFLPH_02166 2.54e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
HAMMFLPH_02167 1.17e-22 degR - - - - - - -
HAMMFLPH_02168 1.05e-40 - - - S - - - Protein of unknown function (DUF2564)
HAMMFLPH_02169 1.54e-37 ypeQ - - S - - - Zinc-finger
HAMMFLPH_02170 4e-163 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
HAMMFLPH_02171 2.4e-138 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HAMMFLPH_02172 1.6e-89 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
HAMMFLPH_02173 5.23e-05 - - - - ko:K06429 - ko00000 -
HAMMFLPH_02174 2.26e-213 ypcP - - L - - - 5'3' exonuclease
HAMMFLPH_02175 1.08e-11 - - - - - - - -
HAMMFLPH_02176 4.07e-52 ypbS - - S - - - Protein of unknown function (DUF2533)
HAMMFLPH_02177 0.0 ypbR - - S - - - Dynamin family
HAMMFLPH_02178 3.33e-113 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
HAMMFLPH_02179 4.55e-266 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
HAMMFLPH_02180 3.14e-294 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
HAMMFLPH_02181 8.16e-129 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HAMMFLPH_02182 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HAMMFLPH_02183 1e-224 kdgT - - P ko:K02526 - ko00000,ko02000 The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
HAMMFLPH_02184 2.53e-133 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
HAMMFLPH_02185 6.95e-238 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
HAMMFLPH_02186 1.92e-238 kdgR - - K ko:K02525 - ko00000,ko03000 transcriptional
HAMMFLPH_02187 1.25e-204 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HAMMFLPH_02188 2.05e-179 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HAMMFLPH_02189 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
HAMMFLPH_02191 2.84e-286 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
HAMMFLPH_02192 2.97e-60 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HAMMFLPH_02193 3.41e-130 ypsA - - S - - - Belongs to the UPF0398 family
HAMMFLPH_02194 7.21e-301 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
HAMMFLPH_02195 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HAMMFLPH_02196 2.34e-113 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
HAMMFLPH_02197 4.33e-95 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HAMMFLPH_02198 8.72e-68 yppG - - S - - - YppG-like protein
HAMMFLPH_02199 9.21e-11 - - - S - - - YppF-like protein
HAMMFLPH_02200 7.9e-10 yppE - - S - - - Bacterial domain of unknown function (DUF1798)
HAMMFLPH_02203 4.54e-241 yppC - - S - - - Protein of unknown function (DUF2515)
HAMMFLPH_02204 3.2e-150 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HAMMFLPH_02205 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HAMMFLPH_02206 1.43e-121 ypoC - - - - - - -
HAMMFLPH_02207 3.57e-158 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HAMMFLPH_02208 6.62e-165 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
HAMMFLPH_02209 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
HAMMFLPH_02210 1.07e-285 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
HAMMFLPH_02211 2.27e-103 ypmB - - S - - - protein conserved in bacteria
HAMMFLPH_02212 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
HAMMFLPH_02213 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
HAMMFLPH_02214 4.16e-85 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HAMMFLPH_02215 1.34e-200 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HAMMFLPH_02216 4.85e-194 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HAMMFLPH_02217 4.87e-234 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HAMMFLPH_02218 1.41e-283 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HAMMFLPH_02219 1.04e-268 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
HAMMFLPH_02220 6.61e-167 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
HAMMFLPH_02221 1.52e-94 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
HAMMFLPH_02222 8.38e-190 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HAMMFLPH_02223 2.47e-74 ypjD - - S - - - Nucleotide pyrophosphohydrolase
HAMMFLPH_02224 3.7e-200 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
HAMMFLPH_02225 6.84e-183 ypjB - - S - - - sporulation protein
HAMMFLPH_02226 1.63e-125 ypjA - - S - - - membrane
HAMMFLPH_02227 5.71e-191 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
HAMMFLPH_02228 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
HAMMFLPH_02229 3.35e-126 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
HAMMFLPH_02230 4.75e-101 ypiF - - S - - - Protein of unknown function (DUF2487)
HAMMFLPH_02231 1.29e-129 ypiB - - S - - - Belongs to the UPF0302 family
HAMMFLPH_02232 5.27e-299 ypiA - - S - - - COG0457 FOG TPR repeat
HAMMFLPH_02233 9.91e-302 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HAMMFLPH_02234 1.71e-264 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
HAMMFLPH_02235 4.5e-259 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HAMMFLPH_02236 3.82e-186 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HAMMFLPH_02237 9.33e-295 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HAMMFLPH_02238 2.82e-153 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
HAMMFLPH_02239 4.18e-145 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
HAMMFLPH_02240 6.08e-230 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HAMMFLPH_02241 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HAMMFLPH_02242 9.82e-84 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
HAMMFLPH_02243 8.48e-265 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HAMMFLPH_02244 1.44e-277 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HAMMFLPH_02245 3.69e-183 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
HAMMFLPH_02246 2.17e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HAMMFLPH_02247 4.09e-249 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HAMMFLPH_02248 1.34e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HAMMFLPH_02249 8.72e-178 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
HAMMFLPH_02250 5.13e-46 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
HAMMFLPH_02251 4.41e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
HAMMFLPH_02252 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HAMMFLPH_02253 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HAMMFLPH_02254 9.07e-178 yphF - - - - - - -
HAMMFLPH_02255 7.09e-27 yphE - - S - - - Protein of unknown function (DUF2768)
HAMMFLPH_02256 2.01e-243 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
HAMMFLPH_02257 4.77e-316 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
HAMMFLPH_02258 8.69e-40 ypzH - - - - - - -
HAMMFLPH_02259 4.35e-207 yphB - - S ko:K05739 - ko00000 YIEGIA protein
HAMMFLPH_02260 2.73e-134 yphA - - - - - - -
HAMMFLPH_02261 1.13e-11 - - - S - - - YpzI-like protein
HAMMFLPH_02262 8.41e-238 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HAMMFLPH_02263 9.5e-263 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
HAMMFLPH_02264 1.73e-147 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
HAMMFLPH_02265 1.74e-32 - - - S - - - Family of unknown function (DUF5359)
HAMMFLPH_02266 4.63e-144 ypfA - - M - - - Flagellar protein YcgR
HAMMFLPH_02267 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
HAMMFLPH_02268 4.88e-208 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
HAMMFLPH_02269 4.33e-154 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
HAMMFLPH_02270 1.62e-227 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
HAMMFLPH_02271 1.42e-308 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
HAMMFLPH_02272 5.56e-136 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HAMMFLPH_02273 4.33e-188 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
HAMMFLPH_02274 1.42e-106 ypbF - - S - - - Protein of unknown function (DUF2663)
HAMMFLPH_02275 5.04e-148 ypbE - - M - - - Lysin motif
HAMMFLPH_02276 6.13e-129 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
HAMMFLPH_02277 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
HAMMFLPH_02278 5.67e-258 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
HAMMFLPH_02279 8.35e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
HAMMFLPH_02280 3.07e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HAMMFLPH_02281 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HAMMFLPH_02282 2.89e-175 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HAMMFLPH_02283 2.7e-257 rsiX - - - - - - -
HAMMFLPH_02284 1.08e-133 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HAMMFLPH_02285 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HAMMFLPH_02286 1.69e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HAMMFLPH_02287 4.67e-279 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HAMMFLPH_02288 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
HAMMFLPH_02289 1.5e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HAMMFLPH_02290 4.45e-169 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HAMMFLPH_02291 8.62e-114 spmB - - S ko:K06374 - ko00000 Spore maturation protein
HAMMFLPH_02292 7.57e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
HAMMFLPH_02293 4.11e-273 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HAMMFLPH_02294 6.13e-128 ypuI - - S - - - Protein of unknown function (DUF3907)
HAMMFLPH_02295 2e-135 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HAMMFLPH_02296 1.33e-167 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HAMMFLPH_02297 3.18e-123 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
HAMMFLPH_02298 1.12e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HAMMFLPH_02299 8.41e-107 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HAMMFLPH_02300 3.12e-292 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HAMMFLPH_02301 1.24e-147 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
HAMMFLPH_02302 1.77e-261 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HAMMFLPH_02303 2.96e-72 ypuD - - - - - - -
HAMMFLPH_02304 1.18e-132 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HAMMFLPH_02305 1.28e-45 ypzJ - - S ko:K07069 - ko00000 nucleic-acid-binding protein containing a Zn-ribbon domain
HAMMFLPH_02307 3.82e-09 - - - S - - - SNARE associated Golgi protein
HAMMFLPH_02309 1.23e-105 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HAMMFLPH_02310 2.67e-193 ypuA - - S - - - Secreted protein
HAMMFLPH_02311 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HAMMFLPH_02312 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
HAMMFLPH_02313 1.85e-143 - - - S ko:K06407 - ko00000 stage V sporulation protein
HAMMFLPH_02314 2.15e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
HAMMFLPH_02315 6.02e-246 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
HAMMFLPH_02316 6.71e-102 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
HAMMFLPH_02317 5.43e-90 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
HAMMFLPH_02318 5.72e-144 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
HAMMFLPH_02319 1.18e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HAMMFLPH_02320 6.78e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HAMMFLPH_02321 1.98e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
HAMMFLPH_02322 2.89e-272 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HAMMFLPH_02323 1.39e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HAMMFLPH_02324 2.89e-295 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
HAMMFLPH_02325 3.91e-214 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
HAMMFLPH_02326 2.73e-50 - - - S - - - Protein of unknown function (DUF4227)
HAMMFLPH_02327 2.26e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
HAMMFLPH_02328 1.96e-139 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
HAMMFLPH_02329 3.73e-44 yqkK - - - - - - -
HAMMFLPH_02330 3.95e-309 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
HAMMFLPH_02331 0.0 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
HAMMFLPH_02332 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
HAMMFLPH_02333 1.77e-238 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
HAMMFLPH_02334 3.18e-77 ansR - - K - - - Transcriptional regulator
HAMMFLPH_02335 2.62e-283 yqxK - - L - - - DNA helicase
HAMMFLPH_02336 4.07e-120 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
HAMMFLPH_02337 8.21e-10 - - - S - - - Protein of unknown function (DUF3936)
HAMMFLPH_02338 9.26e-218 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
HAMMFLPH_02339 1.78e-29 yqkE - - S - - - Protein of unknown function (DUF3886)
HAMMFLPH_02340 4.29e-227 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
HAMMFLPH_02341 1.12e-53 yqkC - - S - - - Protein of unknown function (DUF2552)
HAMMFLPH_02342 6.17e-73 yqkB - - S - - - Belongs to the HesB IscA family
HAMMFLPH_02343 2.89e-251 yqkA - - K - - - GrpB protein
HAMMFLPH_02344 5.51e-79 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
HAMMFLPH_02345 5.46e-113 yqjY - - K ko:K06977 - ko00000 acetyltransferase
HAMMFLPH_02346 1.87e-65 yqiX - - S - - - YolD-like protein
HAMMFLPH_02347 4.03e-304 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HAMMFLPH_02349 1.08e-289 yqjV - - G - - - Major Facilitator Superfamily
HAMMFLPH_02351 1.33e-95 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HAMMFLPH_02352 6.6e-229 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
HAMMFLPH_02353 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
HAMMFLPH_02354 3.41e-185 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
HAMMFLPH_02355 3.98e-230 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
HAMMFLPH_02356 6.84e-190 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HAMMFLPH_02357 0.0 rocB - - E - - - arginine degradation protein
HAMMFLPH_02358 1.21e-245 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HAMMFLPH_02359 3.86e-188 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HAMMFLPH_02360 7.66e-222 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HAMMFLPH_02361 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HAMMFLPH_02362 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HAMMFLPH_02363 2.72e-301 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HAMMFLPH_02364 1.77e-32 yqzJ - - - - - - -
HAMMFLPH_02365 3.36e-184 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HAMMFLPH_02366 8.77e-184 yqjF - - S ko:K09166 - ko00000 Uncharacterized conserved protein (COG2071)
HAMMFLPH_02367 5.26e-259 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
HAMMFLPH_02368 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HAMMFLPH_02369 7.17e-99 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
HAMMFLPH_02371 2.41e-128 yqjB - - S - - - protein conserved in bacteria
HAMMFLPH_02372 9.33e-226 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
HAMMFLPH_02373 1.28e-166 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
HAMMFLPH_02374 8.94e-143 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
HAMMFLPH_02375 1.43e-175 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
HAMMFLPH_02376 3.79e-101 yqiW - - S - - - Belongs to the UPF0403 family
HAMMFLPH_02377 4.23e-214 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HAMMFLPH_02378 3.09e-267 norA - - EGP ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
HAMMFLPH_02379 6.38e-195 - - - K ko:K19575 - ko00000,ko00002,ko03000 helix_turn_helix, mercury resistance
HAMMFLPH_02380 1.57e-296 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HAMMFLPH_02381 6.92e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HAMMFLPH_02382 1.92e-238 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HAMMFLPH_02383 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HAMMFLPH_02384 1.18e-255 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
HAMMFLPH_02385 1.92e-262 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
HAMMFLPH_02386 6.35e-201 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
HAMMFLPH_02387 0.0 bkdR - - KT - - - Transcriptional regulator
HAMMFLPH_02388 1.56e-46 yqzF - - S - - - Protein of unknown function (DUF2627)
HAMMFLPH_02389 1.07e-209 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HAMMFLPH_02390 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
HAMMFLPH_02391 1.66e-267 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
HAMMFLPH_02392 5.16e-270 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
HAMMFLPH_02393 7.2e-201 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
HAMMFLPH_02394 5.7e-281 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
HAMMFLPH_02395 3.68e-172 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
HAMMFLPH_02396 5.67e-139 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
HAMMFLPH_02397 2.26e-37 - - - - - - - -
HAMMFLPH_02398 1.77e-276 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
HAMMFLPH_02400 1.89e-186 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HAMMFLPH_02401 1.26e-303 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
HAMMFLPH_02402 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
HAMMFLPH_02403 3.75e-103 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
HAMMFLPH_02404 1.77e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
HAMMFLPH_02405 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HAMMFLPH_02406 4.2e-209 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HAMMFLPH_02407 1.09e-51 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HAMMFLPH_02408 2.5e-312 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HAMMFLPH_02409 1.07e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HAMMFLPH_02410 4.8e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HAMMFLPH_02411 1.65e-88 yqhY - - S - - - protein conserved in bacteria
HAMMFLPH_02412 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HAMMFLPH_02413 3.21e-93 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HAMMFLPH_02414 9.92e-135 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
HAMMFLPH_02415 9.25e-150 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
HAMMFLPH_02416 1.28e-131 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
HAMMFLPH_02417 7.65e-257 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
HAMMFLPH_02418 1.93e-77 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
HAMMFLPH_02419 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
HAMMFLPH_02420 6.93e-112 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
HAMMFLPH_02421 1.22e-218 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
HAMMFLPH_02422 6.96e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
HAMMFLPH_02423 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HAMMFLPH_02424 3.65e-250 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
HAMMFLPH_02425 1.17e-101 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
HAMMFLPH_02426 8.02e-121 yqhR - - S - - - Conserved membrane protein YqhR
HAMMFLPH_02427 4.42e-222 yqhQ - - S - - - Protein of unknown function (DUF1385)
HAMMFLPH_02428 5.18e-81 yqhP - - - - - - -
HAMMFLPH_02429 1.21e-210 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
HAMMFLPH_02430 1.97e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HAMMFLPH_02431 1.12e-204 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HAMMFLPH_02432 7.5e-83 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
HAMMFLPH_02433 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HAMMFLPH_02434 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HAMMFLPH_02435 8.13e-263 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
HAMMFLPH_02436 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
HAMMFLPH_02437 9.14e-197 yqhG - - S - - - Bacterial protein YqhG of unknown function
HAMMFLPH_02438 4.84e-34 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
HAMMFLPH_02439 3.69e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
HAMMFLPH_02440 1.56e-182 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
HAMMFLPH_02441 7.4e-98 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
HAMMFLPH_02442 8.73e-160 yqxM - - - ko:K19433 - ko00000 -
HAMMFLPH_02443 6.36e-71 yqzG - - S - - - Protein of unknown function (DUF3889)
HAMMFLPH_02444 4.9e-37 yqzE - - S - - - YqzE-like protein
HAMMFLPH_02445 2.55e-55 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
HAMMFLPH_02446 3.44e-65 comGF - - U ko:K02246,ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
HAMMFLPH_02447 4.35e-79 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
HAMMFLPH_02448 9.7e-94 gspH - - NU ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02035,ko02044 protein transport across the cell outer membrane
HAMMFLPH_02449 5.33e-63 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
HAMMFLPH_02450 1.29e-220 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
HAMMFLPH_02451 9.05e-257 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HAMMFLPH_02453 1.51e-233 yqxL - - P - - - Mg2 transporter protein
HAMMFLPH_02454 8.56e-307 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
HAMMFLPH_02455 1.06e-193 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HAMMFLPH_02457 7.79e-85 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
HAMMFLPH_02458 1.46e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
HAMMFLPH_02459 5.52e-158 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
HAMMFLPH_02460 1.91e-31 yqgW - - S - - - Protein of unknown function (DUF2759)
HAMMFLPH_02461 7.34e-66 yqgV - - S - - - Thiamine-binding protein
HAMMFLPH_02462 5.65e-258 yqgU - - - - - - -
HAMMFLPH_02463 1.06e-283 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
HAMMFLPH_02464 0.0 yqgS 2.7.8.20 - M ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
HAMMFLPH_02465 2.81e-231 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
HAMMFLPH_02466 9.15e-45 yqgQ - - S - - - Protein conserved in bacteria
HAMMFLPH_02467 0.0 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
HAMMFLPH_02468 3.38e-14 yqgO - - - - - - -
HAMMFLPH_02469 2.38e-138 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HAMMFLPH_02470 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HAMMFLPH_02471 1.24e-260 yqgM 2.4.1.250 - M ko:K15521 - ko00000,ko01000 Glycosyl transferases group 1
HAMMFLPH_02473 3.42e-68 yqzD - - - - - - -
HAMMFLPH_02474 2.92e-98 yqzC - - S - - - YceG-like family
HAMMFLPH_02475 2.71e-187 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HAMMFLPH_02476 2.4e-190 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HAMMFLPH_02477 5.26e-202 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
HAMMFLPH_02478 7.43e-205 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
HAMMFLPH_02479 4.51e-206 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
HAMMFLPH_02480 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
HAMMFLPH_02481 3.96e-293 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
HAMMFLPH_02482 1.59e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
HAMMFLPH_02483 8.25e-101 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
HAMMFLPH_02484 9.27e-172 yqgB - - S - - - Protein of unknown function (DUF1189)
HAMMFLPH_02485 2.05e-99 yqgA - - - - - - -
HAMMFLPH_02486 2.84e-63 yqfZ - - M ko:K06417 - ko00000 LysM domain
HAMMFLPH_02487 5.22e-257 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HAMMFLPH_02488 2.04e-81 yqfX - - S - - - membrane
HAMMFLPH_02489 8.25e-142 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
HAMMFLPH_02490 8.59e-107 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
HAMMFLPH_02491 3.83e-199 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
HAMMFLPH_02492 3.01e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
HAMMFLPH_02493 1.04e-214 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HAMMFLPH_02494 5.42e-311 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HAMMFLPH_02495 4.89e-58 yqfQ - - S - - - YqfQ-like protein
HAMMFLPH_02496 8.66e-227 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HAMMFLPH_02497 2.27e-270 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HAMMFLPH_02498 2.41e-150 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
HAMMFLPH_02499 1.61e-81 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
HAMMFLPH_02500 2.79e-254 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HAMMFLPH_02501 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HAMMFLPH_02502 6.03e-114 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
HAMMFLPH_02503 6.38e-191 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HAMMFLPH_02504 3.29e-144 ccpN - - K - - - CBS domain
HAMMFLPH_02505 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
HAMMFLPH_02506 2.12e-222 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
HAMMFLPH_02507 5.26e-187 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
HAMMFLPH_02508 5.29e-27 - - - S - - - YqzL-like protein
HAMMFLPH_02509 9.98e-215 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HAMMFLPH_02510 6.71e-93 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HAMMFLPH_02511 1.42e-81 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
HAMMFLPH_02512 8.68e-106 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HAMMFLPH_02513 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
HAMMFLPH_02515 2.47e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
HAMMFLPH_02516 1.04e-242 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
HAMMFLPH_02517 2.07e-60 yqfC - - S - - - sporulation protein YqfC
HAMMFLPH_02518 3.13e-79 yqfB - - - - - - -
HAMMFLPH_02519 4.35e-192 yqfA - - S - - - UPF0365 protein
HAMMFLPH_02520 7.97e-292 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
HAMMFLPH_02521 2.25e-90 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
HAMMFLPH_02522 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
HAMMFLPH_02523 3.45e-202 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
HAMMFLPH_02524 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
HAMMFLPH_02525 1.01e-180 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HAMMFLPH_02526 5.63e-226 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
HAMMFLPH_02527 3.41e-257 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HAMMFLPH_02528 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
HAMMFLPH_02529 4.36e-116 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HAMMFLPH_02530 1.65e-241 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HAMMFLPH_02531 4.3e-278 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
HAMMFLPH_02532 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HAMMFLPH_02533 6.28e-73 yqxA - - S - - - Protein of unknown function (DUF3679)
HAMMFLPH_02534 9.53e-284 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
HAMMFLPH_02535 4.16e-259 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HAMMFLPH_02536 4e-49 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
HAMMFLPH_02537 2.01e-244 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
HAMMFLPH_02538 2.36e-22 - - - S - - - YqzM-like protein
HAMMFLPH_02539 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
HAMMFLPH_02540 3.25e-137 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
HAMMFLPH_02541 6.65e-138 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
HAMMFLPH_02542 2.69e-189 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HAMMFLPH_02543 9.8e-179 yqeM - - Q - - - Methyltransferase
HAMMFLPH_02544 9.76e-82 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HAMMFLPH_02545 4.81e-133 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
HAMMFLPH_02546 2.47e-141 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HAMMFLPH_02547 8.95e-61 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
HAMMFLPH_02548 8.44e-201 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HAMMFLPH_02549 4.78e-273 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HAMMFLPH_02550 2.17e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
HAMMFLPH_02552 2.24e-182 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
HAMMFLPH_02553 7.45e-180 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
HAMMFLPH_02554 3.97e-136 yqeD - - S - - - SNARE associated Golgi protein
HAMMFLPH_02555 7.95e-219 yqeC 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconate dehydrogenase
HAMMFLPH_02556 9.38e-171 - - - - - - - -
HAMMFLPH_02557 2.53e-97 nucB - - M - - - Deoxyribonuclease NucA/NucB
HAMMFLPH_02558 1.1e-72 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HAMMFLPH_02559 0.0 - - - L ko:K06400 - ko00000 Recombinase
HAMMFLPH_02560 9.82e-101 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Catalyzes the reduction of arsenate As(V) to arsenite As(III)
HAMMFLPH_02561 7.13e-233 arsB - - P ko:K03325 - ko00000,ko02000 Arsenic resistance protein
HAMMFLPH_02562 2.56e-104 cadI 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HAMMFLPH_02563 1.53e-72 arsR - - K ko:K03892 - ko00000,ko03000 ArsR family transcriptional regulator
HAMMFLPH_02564 2.08e-197 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
HAMMFLPH_02565 8.68e-120 - - - S - - - Tetratricopeptide repeat
HAMMFLPH_02568 0.0 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
HAMMFLPH_02569 1.66e-136 - - - S ko:K21492 - ko00000,ko02048 Suppressor of fused protein (SUFU)
HAMMFLPH_02571 5.4e-80 - - - - - - - -
HAMMFLPH_02573 9.72e-187 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
HAMMFLPH_02574 8.36e-89 - - - S - - - Bacteriophage holin family
HAMMFLPH_02575 2.45e-213 xepA - - - - - - -
HAMMFLPH_02576 9.34e-33 - - - - - - - -
HAMMFLPH_02577 1.01e-73 xkdW - - S - - - XkdW protein
HAMMFLPH_02578 2.91e-283 - - - - - - - -
HAMMFLPH_02579 3e-54 - - - - - - - -
HAMMFLPH_02580 4.58e-134 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
HAMMFLPH_02581 1.31e-245 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HAMMFLPH_02582 1.14e-91 xkdS - - S - - - Protein of unknown function (DUF2634)
HAMMFLPH_02583 6.68e-52 xkdR - - S - - - Protein of unknown function (DUF2577)
HAMMFLPH_02584 6.49e-131 xkdQ - - G - - - NLP P60 protein
HAMMFLPH_02585 4.97e-69 xkdQ - - G - - - NLP P60 protein
HAMMFLPH_02586 6.56e-156 xkdP - - S - - - Lysin motif
HAMMFLPH_02587 0.0 xkdO - - L - - - Transglycosylase SLT domain
HAMMFLPH_02588 9.14e-88 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
HAMMFLPH_02590 4.23e-99 xkdM - - S - - - Phage tail tube protein
HAMMFLPH_02591 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
HAMMFLPH_02592 2.52e-36 - - - - - - - -
HAMMFLPH_02593 3.24e-102 yqbJ - - - - - - -
HAMMFLPH_02594 7.59e-123 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
HAMMFLPH_02595 7.08e-85 yqbH - - S - - - Domain of unknown function (DUF3599)
HAMMFLPH_02596 7.09e-88 - - - S - - - Protein of unknown function (DUF3199)
HAMMFLPH_02597 2.47e-68 - - - S - - - YqbF, hypothetical protein domain
HAMMFLPH_02598 9.21e-216 xkdG - - S - - - Phage capsid family
HAMMFLPH_02599 5.46e-186 yqbD - - L - - - Putative phage serine protease XkdF
HAMMFLPH_02600 2.13e-149 - - - - - - - -
HAMMFLPH_02601 1.73e-217 - - - S - - - Phage Mu protein F like protein
HAMMFLPH_02602 0.0 yqbA - - S - - - portal protein
HAMMFLPH_02603 0.0 yqaT - - S ko:K06909 - ko00000 phage terminase, large subunit
HAMMFLPH_02604 2.02e-158 yqaS - - L - - - DNA packaging
HAMMFLPH_02606 1.58e-105 yqaQ - - L - - - Transposase
HAMMFLPH_02607 7.56e-214 - - - - - - - -
HAMMFLPH_02608 2.49e-43 yqaO - - S - - - Phage-like element PBSX protein XtrA
HAMMFLPH_02609 1.38e-97 rusA - - L - - - Endodeoxyribonuclease RusA
HAMMFLPH_02611 4.9e-214 yqaM - - L - - - IstB-like ATP binding protein
HAMMFLPH_02612 1.92e-158 yqaL - - L - - - DnaD domain protein
HAMMFLPH_02613 1.1e-198 recT - - L ko:K07455 - ko00000,ko03400 RecT family
HAMMFLPH_02614 7.71e-228 yqaJ - - L - - - YqaJ-like viral recombinase domain
HAMMFLPH_02618 1.27e-134 - - - - - - - -
HAMMFLPH_02620 3.43e-49 - - - K - - - Helix-turn-helix XRE-family like proteins
HAMMFLPH_02621 1.25e-74 - - - K - - - sequence-specific DNA binding
HAMMFLPH_02623 3.9e-130 yqaC - - F - - - adenylate kinase activity
HAMMFLPH_02624 2.25e-131 xkdA - - E - - - IrrE N-terminal-like domain
HAMMFLPH_02625 1.42e-78 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HAMMFLPH_02626 2.15e-90 psiE - - S ko:K13256 - ko00000 Protein PsiE homolog
HAMMFLPH_02627 7.32e-306 yrkQ - - T - - - Histidine kinase
HAMMFLPH_02628 1.24e-164 yrkP - - T ko:K02483 - ko00000,ko02022 Transcriptional regulator
HAMMFLPH_02629 7.53e-283 yrkO - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
HAMMFLPH_02630 1.33e-134 yrkN - - K - - - Acetyltransferase (GNAT) family
HAMMFLPH_02631 5.71e-126 yrkL - - S ko:K11748 - ko00000,ko02000 Flavodoxin-like fold
HAMMFLPH_02632 3.13e-104 - - - S - - - Protein of unknown function with HXXEE motif
HAMMFLPH_02633 1.21e-170 yrkJ - - S ko:K07090 - ko00000 membrane transporter protein
HAMMFLPH_02634 1.11e-49 yrkI - - O - - - Belongs to the sulfur carrier protein TusA family
HAMMFLPH_02635 2.1e-272 yrkH - - P - - - Rhodanese Homology Domain
HAMMFLPH_02636 2.04e-129 yrkF - - OP - - - Belongs to the sulfur carrier protein TusA family
HAMMFLPH_02637 2.38e-109 yrkE - - O - - - DsrE/DsrF/DrsH-like family
HAMMFLPH_02638 4.38e-52 yrkD - - S - - - protein conserved in bacteria
HAMMFLPH_02639 3.81e-139 yrkC - - G - - - Cupin domain
HAMMFLPH_02640 2.15e-195 bltR - - K - - - helix_turn_helix, mercury resistance
HAMMFLPH_02641 1.31e-269 blt - - EGP ko:K08153,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
HAMMFLPH_02642 3.73e-109 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
HAMMFLPH_02643 1.58e-301 yrkA - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
HAMMFLPH_02644 7.28e-25 - - - S - - - YrzO-like protein
HAMMFLPH_02645 1.53e-219 yrdR - - EG - - - EamA-like transporter family
HAMMFLPH_02646 1.2e-204 - - - K - - - Transcriptional regulator
HAMMFLPH_02647 2.58e-255 trkA - - P ko:K07222 - ko00000 Oxidoreductase
HAMMFLPH_02648 2.26e-216 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
HAMMFLPH_02649 1.75e-87 yodA - - S - - - tautomerase
HAMMFLPH_02650 2.08e-209 - - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
HAMMFLPH_02652 2.22e-295 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HAMMFLPH_02653 1.97e-66 azlD - - E - - - Branched-chain amino acid transport protein (AzlD)
HAMMFLPH_02654 2.29e-176 azlC - - E - - - AzlC protein
HAMMFLPH_02655 1.44e-104 bkdR - - K - - - helix_turn_helix ASNC type
HAMMFLPH_02656 1.07e-61 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
HAMMFLPH_02657 1.75e-295 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
HAMMFLPH_02659 7.37e-133 yrdC - - Q - - - Isochorismatase family
HAMMFLPH_02660 2.28e-75 - - - S - - - Protein of unknown function (DUF2568)
HAMMFLPH_02661 1.47e-120 yrdA - - S - - - DinB family
HAMMFLPH_02662 2.66e-215 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
HAMMFLPH_02663 3.79e-249 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
HAMMFLPH_02664 8.73e-191 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
HAMMFLPH_02665 5.87e-163 yrpD - - S - - - Domain of unknown function, YrpD
HAMMFLPH_02667 9.28e-170 zinT - - S ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
HAMMFLPH_02668 1.1e-124 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HAMMFLPH_02669 5.96e-240 yrpG - - C - - - Aldo/keto reductase family
HAMMFLPH_02670 9.19e-287 yraO - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
HAMMFLPH_02671 5.13e-211 yraN - - K - - - Transcriptional regulator
HAMMFLPH_02672 7.25e-264 yraM - - S - - - PrpF protein
HAMMFLPH_02674 5.73e-202 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
HAMMFLPH_02675 6.15e-57 yraL - - S - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HAMMFLPH_02676 4.9e-200 - - - S - - - Alpha beta hydrolase
HAMMFLPH_02677 6.61e-80 - - - T - - - sh3 domain protein
HAMMFLPH_02678 2.92e-81 - - - T - - - sh3 domain protein
HAMMFLPH_02679 6.62e-87 - - - E - - - Glyoxalase-like domain
HAMMFLPH_02680 4.19e-50 yraG - - - ko:K06440 - ko00000 -
HAMMFLPH_02681 9.61e-84 yraF - - M - - - Spore coat protein
HAMMFLPH_02682 9.1e-284 adhB 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HAMMFLPH_02683 1.05e-36 yraE - - - ko:K06440 - ko00000 -
HAMMFLPH_02684 7.23e-66 yraD - - M ko:K06439 - ko00000 Spore coat protein
HAMMFLPH_02685 3.17e-68 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
HAMMFLPH_02686 3.03e-40 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 peroxiredoxin activity
HAMMFLPH_02687 4.3e-256 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
HAMMFLPH_02688 1.58e-116 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
HAMMFLPH_02689 0.0 sacC 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
HAMMFLPH_02690 1.39e-192 levG - - G ko:K02771,ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
HAMMFLPH_02691 6.11e-168 levF - - G ko:K02746,ko:K02795,ko:K11196 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
HAMMFLPH_02692 7.63e-107 ptnA 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11195 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system mannose fructose sorbose family
HAMMFLPH_02693 2.66e-97 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
HAMMFLPH_02694 0.0 levR - - K - - - PTS system fructose IIA component
HAMMFLPH_02695 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
HAMMFLPH_02696 5.63e-137 yrhP - - E - - - LysE type translocator
HAMMFLPH_02697 5.9e-194 yrhO - - K - - - Archaeal transcriptional regulator TrmB
HAMMFLPH_02698 9.97e-114 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HAMMFLPH_02699 3.67e-193 rsiV - - S - - - Protein of unknown function (DUF3298)
HAMMFLPH_02700 0.0 oatA - - I - - - Acyltransferase family
HAMMFLPH_02701 2.67e-62 yrhK - - S - - - YrhK-like protein
HAMMFLPH_02702 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
HAMMFLPH_02703 1.12e-135 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
HAMMFLPH_02704 1.1e-126 yrhH - - Q - - - methyltransferase
HAMMFLPH_02705 9.39e-08 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
HAMMFLPH_02707 1.38e-183 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
HAMMFLPH_02708 1.08e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
HAMMFLPH_02709 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
HAMMFLPH_02710 4.26e-103 yrhD - - S - - - Protein of unknown function (DUF1641)
HAMMFLPH_02711 6.93e-49 yrhC - - S - - - YrhC-like protein
HAMMFLPH_02712 4.24e-269 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HAMMFLPH_02713 7.04e-218 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
HAMMFLPH_02714 1.97e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HAMMFLPH_02715 7.23e-155 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
HAMMFLPH_02716 8.52e-37 yrzA - - S - - - Protein of unknown function (DUF2536)
HAMMFLPH_02717 1.42e-102 yrrS - - S - - - Protein of unknown function (DUF1510)
HAMMFLPH_02718 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
HAMMFLPH_02719 1.14e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HAMMFLPH_02720 4.51e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
HAMMFLPH_02721 4.62e-313 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
HAMMFLPH_02722 6.57e-224 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
HAMMFLPH_02723 1.7e-155 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
HAMMFLPH_02724 7.51e-242 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HAMMFLPH_02725 2.94e-60 yrzB - - S - - - Belongs to the UPF0473 family
HAMMFLPH_02726 5.49e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HAMMFLPH_02727 2.22e-55 yrzL - - S - - - Belongs to the UPF0297 family
HAMMFLPH_02728 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HAMMFLPH_02729 3.07e-242 yrrI - - S - - - AI-2E family transporter
HAMMFLPH_02730 9.37e-170 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
HAMMFLPH_02731 1.28e-187 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
HAMMFLPH_02732 2.28e-139 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HAMMFLPH_02733 9.26e-140 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HAMMFLPH_02734 5.38e-12 - - - S - - - Protein of unknown function (DUF3918)
HAMMFLPH_02735 8.4e-42 yrzR - - - - - - -
HAMMFLPH_02736 1.23e-108 yrrD - - S - - - protein conserved in bacteria
HAMMFLPH_02737 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HAMMFLPH_02738 1.01e-20 yrrB - - S - - - COG0457 FOG TPR repeat
HAMMFLPH_02739 1.19e-280 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HAMMFLPH_02740 2.67e-272 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
HAMMFLPH_02741 8.12e-93 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
HAMMFLPH_02742 8.5e-304 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HAMMFLPH_02743 3.96e-177 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HAMMFLPH_02744 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HAMMFLPH_02745 1.27e-311 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
HAMMFLPH_02747 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
HAMMFLPH_02748 1.36e-90 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HAMMFLPH_02749 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HAMMFLPH_02750 2.53e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HAMMFLPH_02751 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
HAMMFLPH_02752 1.07e-64 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
HAMMFLPH_02753 6.51e-114 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
HAMMFLPH_02754 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HAMMFLPH_02755 1.93e-65 yrzD - - S - - - Post-transcriptional regulator
HAMMFLPH_02756 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HAMMFLPH_02757 6.34e-147 yrbG - - S - - - membrane
HAMMFLPH_02758 1.07e-98 yrzE - - S - - - Protein of unknown function (DUF3792)
HAMMFLPH_02759 1.29e-52 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
HAMMFLPH_02760 4.74e-292 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HAMMFLPH_02761 6.03e-248 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HAMMFLPH_02762 2.91e-30 yrzS - - S - - - Protein of unknown function (DUF2905)
HAMMFLPH_02763 9.14e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HAMMFLPH_02764 2.84e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HAMMFLPH_02765 6.46e-121 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
HAMMFLPH_02766 0.0 csbX - - EGP - - - the major facilitator superfamily
HAMMFLPH_02767 2.77e-248 idhA 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
HAMMFLPH_02768 2.32e-152 yrzF - - T - - - serine threonine protein kinase
HAMMFLPH_02770 2.42e-47 - - - S - - - Family of unknown function (DUF5412)
HAMMFLPH_02771 0.0 yrbD - - E ko:K03310 - ko00000 Sodium alanine symporter
HAMMFLPH_02772 8.63e-165 yebC - - K - - - transcriptional regulatory protein
HAMMFLPH_02773 7.28e-70 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HAMMFLPH_02774 1.71e-217 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
HAMMFLPH_02775 7.94e-273 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HAMMFLPH_02776 8.17e-208 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
HAMMFLPH_02777 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
HAMMFLPH_02778 1.27e-294 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
HAMMFLPH_02779 5.02e-123 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
HAMMFLPH_02780 4.99e-209 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
HAMMFLPH_02781 4.75e-96 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
HAMMFLPH_02782 9.66e-309 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HAMMFLPH_02783 4.25e-139 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
HAMMFLPH_02784 2.7e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
HAMMFLPH_02785 2.66e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
HAMMFLPH_02786 6.34e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
HAMMFLPH_02787 3.74e-208 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
HAMMFLPH_02788 1.83e-187 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
HAMMFLPH_02789 2.91e-186 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
HAMMFLPH_02790 4.3e-158 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HAMMFLPH_02791 8.72e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
HAMMFLPH_02792 1.91e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
HAMMFLPH_02793 5.26e-235 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
HAMMFLPH_02794 8.35e-163 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
HAMMFLPH_02795 1.73e-132 maf - - D ko:K06287 - ko00000 septum formation protein Maf
HAMMFLPH_02796 4.67e-215 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
HAMMFLPH_02797 3.15e-109 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HAMMFLPH_02798 5.8e-316 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
HAMMFLPH_02799 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HAMMFLPH_02800 1.53e-35 - - - - - - - -
HAMMFLPH_02801 2.91e-253 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HAMMFLPH_02802 0.0 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
HAMMFLPH_02803 8.99e-315 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
HAMMFLPH_02804 6.39e-234 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
HAMMFLPH_02805 1.57e-187 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
HAMMFLPH_02806 2.66e-221 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HAMMFLPH_02807 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
HAMMFLPH_02808 6.39e-316 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HAMMFLPH_02809 8.23e-117 ysxD - - - - - - -
HAMMFLPH_02810 7.6e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
HAMMFLPH_02811 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HAMMFLPH_02812 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
HAMMFLPH_02813 1.15e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HAMMFLPH_02814 8.87e-287 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HAMMFLPH_02815 2.73e-240 ysoA - - H - - - Tetratricopeptide repeat
HAMMFLPH_02816 5.35e-150 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HAMMFLPH_02817 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HAMMFLPH_02818 1.06e-255 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HAMMFLPH_02819 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HAMMFLPH_02820 9.59e-245 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HAMMFLPH_02821 5.05e-110 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
HAMMFLPH_02822 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
HAMMFLPH_02824 3.32e-107 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
HAMMFLPH_02825 1.01e-184 ysnF - - S - - - protein conserved in bacteria
HAMMFLPH_02827 4.05e-119 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
HAMMFLPH_02828 1.06e-132 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HAMMFLPH_02829 3.53e-171 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HAMMFLPH_02830 8.03e-256 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
HAMMFLPH_02831 1.15e-196 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
HAMMFLPH_02832 1.6e-98 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
HAMMFLPH_02833 1.81e-41 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
HAMMFLPH_02834 1.6e-103 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
HAMMFLPH_02835 1.15e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
HAMMFLPH_02836 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
HAMMFLPH_02837 1.35e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
HAMMFLPH_02838 8.53e-104 yslB - - S - - - Protein of unknown function (DUF2507)
HAMMFLPH_02839 4.83e-276 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HAMMFLPH_02840 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HAMMFLPH_02841 1.12e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
HAMMFLPH_02842 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
HAMMFLPH_02844 3.02e-228 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
HAMMFLPH_02845 1.28e-179 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
HAMMFLPH_02846 2.2e-176 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
HAMMFLPH_02847 1.21e-130 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
HAMMFLPH_02848 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HAMMFLPH_02849 3.76e-89 yshE - - S ko:K08989 - ko00000 membrane
HAMMFLPH_02850 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HAMMFLPH_02851 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
HAMMFLPH_02852 1.09e-111 yshB - - S - - - membrane protein, required for colicin V production
HAMMFLPH_02853 1.04e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HAMMFLPH_02854 6.77e-219 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HAMMFLPH_02855 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HAMMFLPH_02856 1.81e-250 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HAMMFLPH_02857 7.68e-172 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HAMMFLPH_02858 7.54e-44 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
HAMMFLPH_02859 6.71e-265 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
HAMMFLPH_02860 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Glycolate oxidase subunit
HAMMFLPH_02861 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
HAMMFLPH_02862 8.17e-52 ysfE 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 lactoylglutathione lyase activity
HAMMFLPH_02864 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
HAMMFLPH_02865 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
HAMMFLPH_02866 6.34e-192 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
HAMMFLPH_02867 6.77e-219 araP - - G ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
HAMMFLPH_02868 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
HAMMFLPH_02869 1.47e-288 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
HAMMFLPH_02870 1.05e-187 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
HAMMFLPH_02871 1.7e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HAMMFLPH_02872 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
HAMMFLPH_02873 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
HAMMFLPH_02874 4.21e-243 - 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
HAMMFLPH_02875 4.35e-262 ysdC - - G - - - COG1363 Cellulase M and related proteins
HAMMFLPH_02876 1.96e-89 ysdB - - S - - - Sigma-w pathway protein YsdB
HAMMFLPH_02877 1.27e-59 ysdA - - S - - - Membrane
HAMMFLPH_02878 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HAMMFLPH_02879 3.93e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
HAMMFLPH_02880 1.81e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HAMMFLPH_02882 5.34e-150 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HAMMFLPH_02883 2.08e-85 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HAMMFLPH_02884 2.9e-168 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
HAMMFLPH_02885 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HAMMFLPH_02886 2.07e-191 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
HAMMFLPH_02887 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HAMMFLPH_02888 5.98e-206 ytxC - - S - - - YtxC-like family
HAMMFLPH_02889 9.77e-144 ytxB - - S - - - SNARE associated Golgi protein
HAMMFLPH_02890 1.05e-221 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
HAMMFLPH_02891 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
HAMMFLPH_02892 2.42e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HAMMFLPH_02893 2.42e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HAMMFLPH_02894 1.22e-246 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HAMMFLPH_02895 9.85e-88 ytcD - - K - - - Transcriptional regulator
HAMMFLPH_02896 5.44e-260 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
HAMMFLPH_02897 4.54e-205 ytbE - - S - - - reductase
HAMMFLPH_02898 2.82e-126 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HAMMFLPH_02899 1.68e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
HAMMFLPH_02900 7e-203 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HAMMFLPH_02901 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HAMMFLPH_02902 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
HAMMFLPH_02903 1.62e-169 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HAMMFLPH_02904 2.55e-218 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
HAMMFLPH_02905 2.28e-309 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
HAMMFLPH_02906 1.17e-267 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
HAMMFLPH_02907 9.38e-95 ytwI - - S - - - membrane
HAMMFLPH_02908 2.73e-245 ytvI - - S - - - sporulation integral membrane protein YtvI
HAMMFLPH_02909 5.68e-83 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
HAMMFLPH_02910 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
HAMMFLPH_02911 1.62e-229 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HAMMFLPH_02912 9.82e-234 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HAMMFLPH_02913 2.17e-208 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HAMMFLPH_02914 6.01e-287 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
HAMMFLPH_02915 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
HAMMFLPH_02916 2.45e-75 ytrH - - S - - - Sporulation protein YtrH
HAMMFLPH_02917 5.12e-112 ytrI - - - - - - -
HAMMFLPH_02918 1.15e-39 - - - - - - - -
HAMMFLPH_02919 1.24e-230 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
HAMMFLPH_02920 2.15e-63 ytpI - - S - - - YtpI-like protein
HAMMFLPH_02921 1.13e-308 ytoI - - K - - - transcriptional regulator containing CBS domains
HAMMFLPH_02922 2.24e-206 ytnM - - S ko:K07090 - ko00000 membrane transporter protein
HAMMFLPH_02923 2.09e-306 hipO2 - - E ko:K01436,ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
HAMMFLPH_02924 1.69e-166 - 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin kinase
HAMMFLPH_02925 0.0 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HAMMFLPH_02926 5.26e-63 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
HAMMFLPH_02927 1.52e-237 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HAMMFLPH_02928 6.61e-183 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
HAMMFLPH_02929 4.08e-156 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HAMMFLPH_02930 1.66e-157 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HAMMFLPH_02931 4.01e-194 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
HAMMFLPH_02932 3.18e-195 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
HAMMFLPH_02933 8.39e-130 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
HAMMFLPH_02934 4.99e-223 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
HAMMFLPH_02935 1.91e-166 ytkL - - S - - - Belongs to the UPF0173 family
HAMMFLPH_02936 1.98e-182 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HAMMFLPH_02938 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
HAMMFLPH_02939 1.06e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
HAMMFLPH_02940 8.14e-115 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
HAMMFLPH_02941 4.69e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HAMMFLPH_02942 3.78e-224 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
HAMMFLPH_02943 1.93e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HAMMFLPH_02944 2.24e-96 ytfJ - - S - - - Sporulation protein YtfJ
HAMMFLPH_02945 5.03e-150 ytfI - - S - - - Protein of unknown function (DUF2953)
HAMMFLPH_02946 7.05e-113 yteJ - - S - - - RDD family
HAMMFLPH_02947 6.13e-233 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
HAMMFLPH_02948 2.92e-190 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HAMMFLPH_02949 0.0 ytcJ - - S - - - amidohydrolase
HAMMFLPH_02950 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HAMMFLPH_02951 2.12e-40 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
HAMMFLPH_02952 6.26e-289 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HAMMFLPH_02953 1.22e-269 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
HAMMFLPH_02954 1.17e-304 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HAMMFLPH_02955 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HAMMFLPH_02956 3.73e-198 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
HAMMFLPH_02957 2.94e-142 yttP - - K - - - Transcriptional regulator
HAMMFLPH_02958 1.95e-114 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
HAMMFLPH_02959 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
HAMMFLPH_02960 2.01e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HAMMFLPH_02962 6.47e-304 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HAMMFLPH_02963 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HAMMFLPH_02964 2.43e-156 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
HAMMFLPH_02965 6.16e-152 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
HAMMFLPH_02966 6.51e-293 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
HAMMFLPH_02967 1.6e-161 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
HAMMFLPH_02968 1.18e-187 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
HAMMFLPH_02969 4.16e-235 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
HAMMFLPH_02970 7.64e-250 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
HAMMFLPH_02971 1.9e-72 ytxJ - - O - - - Protein of unknown function (DUF2847)
HAMMFLPH_02972 3.17e-30 ytxH - - S - - - COG4980 Gas vesicle protein
HAMMFLPH_02973 1.67e-63 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HAMMFLPH_02974 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
HAMMFLPH_02975 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
HAMMFLPH_02976 1.78e-140 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HAMMFLPH_02977 1.02e-191 ytpQ - - S - - - Belongs to the UPF0354 family
HAMMFLPH_02978 9.1e-75 ytpP - - CO - - - Thioredoxin
HAMMFLPH_02979 7.02e-103 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
HAMMFLPH_02980 2.24e-262 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
HAMMFLPH_02981 4.06e-68 ytzB - - S - - - small secreted protein
HAMMFLPH_02982 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
HAMMFLPH_02983 2.16e-193 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
HAMMFLPH_02984 7.53e-157 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HAMMFLPH_02985 9.51e-61 ytzH - - S - - - YtzH-like protein
HAMMFLPH_02986 3.02e-192 ytmP - - M - - - Phosphotransferase
HAMMFLPH_02987 0.0 amyX 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
HAMMFLPH_02988 2.22e-231 ytlR - - I - - - Diacylglycerol kinase catalytic domain
HAMMFLPH_02989 4.92e-212 ytlQ - - - - - - -
HAMMFLPH_02990 7.71e-133 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HAMMFLPH_02991 3e-221 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HAMMFLPH_02992 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
HAMMFLPH_02993 1.73e-288 pbuO - - S ko:K06901 - ko00000,ko02000 permease
HAMMFLPH_02994 8.45e-263 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
HAMMFLPH_02995 2.4e-169 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HAMMFLPH_02996 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
HAMMFLPH_02997 9.04e-171 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HAMMFLPH_02998 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HAMMFLPH_02999 6.99e-294 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
HAMMFLPH_03000 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
HAMMFLPH_03001 2.14e-36 yteV - - S - - - Sporulation protein Cse60
HAMMFLPH_03002 1.97e-152 yteU - - S - - - Integral membrane protein
HAMMFLPH_03003 0.0 yteT - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
HAMMFLPH_03004 5.81e-95 yteS - - G - - - transport
HAMMFLPH_03005 2.23e-286 yteR 3.2.1.172 GH105 G ko:K15532 - ko00000,ko01000 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HAMMFLPH_03006 2.27e-221 lplB13 - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
HAMMFLPH_03007 0.0 ytdP - - K - - - Transcriptional regulator
HAMMFLPH_03008 0.0 - - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
HAMMFLPH_03009 6.19e-193 ytcP - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
HAMMFLPH_03010 2.21e-178 ytbQ 1.1.1.203, 1.1.1.388 - GM ko:K18981,ko:K19243 ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 NAD dependent epimerase/dehydratase family
HAMMFLPH_03011 2.64e-287 bioI 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
HAMMFLPH_03012 4.57e-244 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HAMMFLPH_03013 5.04e-164 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HAMMFLPH_03014 3.73e-284 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HAMMFLPH_03015 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
HAMMFLPH_03016 4.04e-182 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
HAMMFLPH_03017 1.43e-222 - - - S - - - Acetyl xylan esterase (AXE1)
HAMMFLPH_03018 1.12e-244 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HAMMFLPH_03019 4.68e-315 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HAMMFLPH_03020 2.86e-215 amyD - - P ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HAMMFLPH_03021 1.32e-186 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
HAMMFLPH_03022 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
HAMMFLPH_03023 1.22e-68 ytwF - - P - - - Sulfurtransferase
HAMMFLPH_03024 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
HAMMFLPH_03025 3.63e-72 ytvB - - S - - - Protein of unknown function (DUF4257)
HAMMFLPH_03026 6.61e-184 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
HAMMFLPH_03027 2.98e-269 yttB - - EGP - - - Major facilitator superfamily
HAMMFLPH_03028 2.02e-78 yttA - - S - - - Pfam Transposase IS66
HAMMFLPH_03029 0.0 bceB - - V ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
HAMMFLPH_03030 3.83e-179 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
HAMMFLPH_03031 1.58e-239 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
HAMMFLPH_03032 1.77e-167 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HAMMFLPH_03033 5.92e-298 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
HAMMFLPH_03034 1.02e-163 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HAMMFLPH_03035 1.07e-189 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
HAMMFLPH_03036 3.35e-222 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
HAMMFLPH_03037 1.03e-207 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HAMMFLPH_03038 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
HAMMFLPH_03040 1.27e-55 ytzC - - S - - - Protein of unknown function (DUF2524)
HAMMFLPH_03041 4.06e-245 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
HAMMFLPH_03042 6.76e-137 ytqB - - J - - - Putative rRNA methylase
HAMMFLPH_03043 4.81e-276 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
HAMMFLPH_03044 2.33e-192 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
HAMMFLPH_03045 8.35e-88 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HAMMFLPH_03046 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
HAMMFLPH_03047 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
HAMMFLPH_03048 2.26e-286 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HAMMFLPH_03049 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HAMMFLPH_03050 2.85e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
HAMMFLPH_03051 6.67e-191 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HAMMFLPH_03052 2.77e-242 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HAMMFLPH_03053 1.5e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HAMMFLPH_03054 1.32e-183 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HAMMFLPH_03055 4.47e-113 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
HAMMFLPH_03056 1.59e-81 ytkC - - S - - - Bacteriophage holin family
HAMMFLPH_03057 1.8e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
HAMMFLPH_03059 8.26e-96 ytkA - - S - - - YtkA-like
HAMMFLPH_03060 8.36e-113 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HAMMFLPH_03061 8.96e-134 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
HAMMFLPH_03062 5.02e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
HAMMFLPH_03063 2.81e-316 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
HAMMFLPH_03064 2.96e-241 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
HAMMFLPH_03065 2.43e-34 - - - S - - - Domain of Unknown Function (DUF1540)
HAMMFLPH_03066 9.65e-194 mntD - - P ko:K11709,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
HAMMFLPH_03067 1.64e-299 mntC - - P ko:K11705,ko:K11708,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HAMMFLPH_03068 1.83e-180 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K11710,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HAMMFLPH_03069 1.13e-218 troA - - P ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HAMMFLPH_03070 1.22e-273 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HAMMFLPH_03071 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HAMMFLPH_03072 3.45e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HAMMFLPH_03073 5.09e-199 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
HAMMFLPH_03074 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HAMMFLPH_03075 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
HAMMFLPH_03076 8.68e-169 yteA - - T - - - COG1734 DnaK suppressor protein
HAMMFLPH_03077 1.7e-196 ytdA 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
HAMMFLPH_03078 2.03e-310 ytcA 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HAMMFLPH_03079 7.74e-231 ytcB - - M - - - NAD-dependent epimerase dehydratase
HAMMFLPH_03080 3.7e-300 - - - M ko:K06338 - ko00000 Glycosyltransferase Family 4
HAMMFLPH_03082 1.7e-263 cotS - - S ko:K06337 - ko00000 Seems to be required for the assembly of the CotSA protein in spores
HAMMFLPH_03083 1.75e-276 cotSA - - M ko:K06338 - ko00000 Glycosyl transferases group 1
HAMMFLPH_03084 9.43e-263 cotI - - S ko:K06331 - ko00000 Spore coat protein
HAMMFLPH_03085 1.97e-101 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
HAMMFLPH_03086 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HAMMFLPH_03087 0.0 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
HAMMFLPH_03088 4.34e-237 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Glucose-1-phosphate adenylyltransferase, GlgD subunit
HAMMFLPH_03089 2.96e-265 glgC 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HAMMFLPH_03090 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HAMMFLPH_03112 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
HAMMFLPH_03113 2.52e-122 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
HAMMFLPH_03114 1.2e-122 - - - M - - - FR47-like protein
HAMMFLPH_03115 4.54e-258 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
HAMMFLPH_03116 4.06e-110 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
HAMMFLPH_03117 1.95e-109 yuaE - - S - - - DinB superfamily
HAMMFLPH_03118 8.58e-139 yuaD - - - - - - -
HAMMFLPH_03119 4.26e-292 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
HAMMFLPH_03120 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HAMMFLPH_03121 3.53e-123 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
HAMMFLPH_03122 5.83e-118 yuaB - - - - - - -
HAMMFLPH_03123 1.83e-157 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
HAMMFLPH_03124 1.85e-301 - - - P ko:K03498 - ko00000,ko02000 Potassium
HAMMFLPH_03125 3.31e-52 yubF - - S - - - yiaA/B two helix domain
HAMMFLPH_03126 1.87e-196 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HAMMFLPH_03127 0.0 yubD - - P - - - Major Facilitator Superfamily
HAMMFLPH_03128 6.82e-114 cdoA 1.13.11.20 - S ko:K00456 ko00270,ko00430,ko01100,map00270,map00430,map01100 ko00000,ko00001,ko01000 Cysteine dioxygenase type I
HAMMFLPH_03130 6.02e-183 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HAMMFLPH_03131 3.8e-256 yubA - - S - - - transporter activity
HAMMFLPH_03132 9.11e-236 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
HAMMFLPH_03133 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Belongs to the rhamnose isomerase family
HAMMFLPH_03134 4.94e-73 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
HAMMFLPH_03135 0.0 rhaB 2.7.1.5 - G ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HAMMFLPH_03136 1.42e-172 yulB - - K ko:K02530,ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
HAMMFLPH_03137 0.0 yuxG - - IQ - - - Class II Aldolase and Adducin N-terminal domain
HAMMFLPH_03138 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HAMMFLPH_03139 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HAMMFLPH_03140 6.34e-300 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HAMMFLPH_03141 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HAMMFLPH_03142 1.06e-181 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
HAMMFLPH_03143 5e-48 - - - - - - - -
HAMMFLPH_03144 3.63e-95 yugU - - S - - - Uncharacterised protein family UPF0047
HAMMFLPH_03145 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
HAMMFLPH_03146 1.07e-301 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
HAMMFLPH_03147 4.8e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
HAMMFLPH_03148 1.35e-51 - - - - - - - -
HAMMFLPH_03149 2.12e-70 mstX - - S - - - Membrane-integrating protein Mistic
HAMMFLPH_03150 1.76e-233 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
HAMMFLPH_03151 4.22e-95 yugN - - S - - - YugN-like family
HAMMFLPH_03153 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
HAMMFLPH_03154 5.56e-291 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
HAMMFLPH_03155 2.85e-287 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
HAMMFLPH_03156 2.21e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
HAMMFLPH_03157 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
HAMMFLPH_03158 6.62e-256 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
HAMMFLPH_03159 6.74e-112 alaR - - K - - - Transcriptional regulator
HAMMFLPH_03160 1.2e-201 yugF - - I - - - Hydrolase
HAMMFLPH_03161 6.7e-56 yugE - - S - - - Domain of unknown function (DUF1871)
HAMMFLPH_03162 2.09e-289 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HAMMFLPH_03163 1.06e-296 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HAMMFLPH_03164 4.3e-92 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
HAMMFLPH_03165 8.49e-150 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
HAMMFLPH_03167 1.96e-245 yuxJ - - EGP - - - Major facilitator superfamily
HAMMFLPH_03168 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
HAMMFLPH_03169 3.31e-98 yuxK - - S - - - protein conserved in bacteria
HAMMFLPH_03170 4.19e-113 yufK - - S - - - Family of unknown function (DUF5366)
HAMMFLPH_03171 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
HAMMFLPH_03172 1.14e-162 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
HAMMFLPH_03173 6.34e-254 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
HAMMFLPH_03174 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HAMMFLPH_03175 1.57e-237 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HAMMFLPH_03176 1.47e-216 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HAMMFLPH_03177 9.73e-310 malP - - C ko:K11616 ko02020,map02020 ko00000,ko00001 COG3493 Na citrate symporter
HAMMFLPH_03178 7.06e-22 - - - - - - - -
HAMMFLPH_03179 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HAMMFLPH_03180 7.66e-91 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HAMMFLPH_03181 1.72e-66 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HAMMFLPH_03182 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HAMMFLPH_03183 7.39e-103 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HAMMFLPH_03184 2.23e-51 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HAMMFLPH_03185 5.97e-79 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
HAMMFLPH_03186 3.18e-84 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
HAMMFLPH_03187 2.06e-150 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HAMMFLPH_03188 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HAMMFLPH_03190 1.4e-209 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Polyprenyl synthetase
HAMMFLPH_03191 6.29e-10 - - - S - - - DegQ (SacQ) family
HAMMFLPH_03192 9.63e-08 - - - - - - - -
HAMMFLPH_03193 2.92e-298 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
HAMMFLPH_03194 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HAMMFLPH_03195 5.65e-135 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
HAMMFLPH_03196 1.32e-88 - - - S - - - Protein of unknown function (DUF1694)
HAMMFLPH_03197 1.63e-52 yueH - - S - - - YueH-like protein
HAMMFLPH_03198 1.23e-43 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
HAMMFLPH_03199 4.72e-245 yueF - - S - - - transporter activity
HAMMFLPH_03200 3.97e-93 - - - S - - - Protein of unknown function (DUF2283)
HAMMFLPH_03201 8.4e-33 - - - S - - - Protein of unknown function (DUF2642)
HAMMFLPH_03202 1.91e-125 yueE - - S ko:K06950 - ko00000 phosphohydrolase
HAMMFLPH_03203 6.1e-171 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HAMMFLPH_03204 4.37e-97 yueC - - S - - - Family of unknown function (DUF5383)
HAMMFLPH_03205 0.0 yueB - - S - - - type VII secretion protein EsaA
HAMMFLPH_03206 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HAMMFLPH_03207 4.28e-271 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
HAMMFLPH_03208 1.93e-54 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
HAMMFLPH_03209 3.93e-60 yukE - - S - - - Belongs to the WXG100 family
HAMMFLPH_03210 1.03e-292 yukF - - QT - - - Transcriptional regulator
HAMMFLPH_03211 4.9e-263 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
HAMMFLPH_03212 2.07e-169 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
HAMMFLPH_03213 1.42e-47 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
HAMMFLPH_03214 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HAMMFLPH_03215 3.83e-229 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
HAMMFLPH_03216 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
HAMMFLPH_03217 7.34e-291 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
HAMMFLPH_03218 1.43e-178 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
HAMMFLPH_03219 1.55e-213 eSD - - S ko:K07017 - ko00000 Putative esterase
HAMMFLPH_03220 2.36e-157 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
HAMMFLPH_03221 8.33e-125 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
HAMMFLPH_03222 3.65e-279 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
HAMMFLPH_03223 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HAMMFLPH_03224 8.63e-102 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
HAMMFLPH_03225 3.28e-151 yuiC - - S - - - protein conserved in bacteria
HAMMFLPH_03226 9.78e-47 yuiB - - S - - - Putative membrane protein
HAMMFLPH_03227 4.16e-301 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HAMMFLPH_03228 1.16e-240 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
HAMMFLPH_03230 1.15e-237 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HAMMFLPH_03231 2.96e-151 paiB - - K ko:K07734 - ko00000,ko03000 Putative FMN-binding domain
HAMMFLPH_03232 6.88e-116 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HAMMFLPH_03233 6.81e-83 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
HAMMFLPH_03234 3.9e-208 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HAMMFLPH_03235 1.54e-270 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HAMMFLPH_03236 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
HAMMFLPH_03237 1.12e-253 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HAMMFLPH_03238 6.61e-75 yuzD - - S - - - protein conserved in bacteria
HAMMFLPH_03239 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
HAMMFLPH_03240 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
HAMMFLPH_03241 2.57e-221 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HAMMFLPH_03242 2.4e-253 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HAMMFLPH_03243 1.67e-307 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
HAMMFLPH_03244 4.63e-255 yutH - - S - - - Spore coat protein
HAMMFLPH_03245 2.26e-101 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
HAMMFLPH_03246 3.69e-183 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HAMMFLPH_03247 2.38e-99 yutE - - S - - - Protein of unknown function DUF86
HAMMFLPH_03248 3.2e-63 yutD - - S - - - protein conserved in bacteria
HAMMFLPH_03249 9.45e-145 yutC - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HAMMFLPH_03250 1.37e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HAMMFLPH_03251 2.66e-252 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
HAMMFLPH_03252 4.25e-172 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
HAMMFLPH_03253 3.41e-65 yunC - - S - - - Domain of unknown function (DUF1805)
HAMMFLPH_03254 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HAMMFLPH_03255 6.51e-181 yunE - - S ko:K07090 - ko00000 membrane transporter protein
HAMMFLPH_03256 4.26e-220 yunF - - S - - - Protein of unknown function DUF72
HAMMFLPH_03257 2.72e-82 yunG - - - - - - -
HAMMFLPH_03258 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
HAMMFLPH_03259 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
HAMMFLPH_03260 1.46e-300 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 Permease family
HAMMFLPH_03261 1.65e-285 pbuX - - F ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
HAMMFLPH_03262 0.0 - 1.7.3.3, 4.1.1.97 - Q ko:K16838 ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
HAMMFLPH_03263 1.41e-79 pucM 3.5.2.17 - S ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
HAMMFLPH_03264 1.3e-126 - 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03518 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
HAMMFLPH_03265 0.0 pucD 1.17.1.4 - C ko:K00087 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
HAMMFLPH_03266 4.85e-194 pucC 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03519 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
HAMMFLPH_03267 2.62e-144 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
HAMMFLPH_03268 5.12e-243 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HAMMFLPH_03270 8.51e-306 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
HAMMFLPH_03271 4.9e-303 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HAMMFLPH_03272 6.53e-218 bsn - - L - - - Ribonuclease
HAMMFLPH_03273 2.95e-263 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HAMMFLPH_03274 7.46e-176 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
HAMMFLPH_03275 9.57e-209 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
HAMMFLPH_03276 1.94e-216 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
HAMMFLPH_03277 1.24e-199 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HAMMFLPH_03278 2.46e-308 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
HAMMFLPH_03279 2.24e-236 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
HAMMFLPH_03280 1.2e-87 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
HAMMFLPH_03281 1.42e-268 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
HAMMFLPH_03283 3.35e-56 - - - - - - - -
HAMMFLPH_03284 2.14e-87 yurT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HAMMFLPH_03285 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
HAMMFLPH_03286 6.26e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
HAMMFLPH_03287 2.81e-299 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HAMMFLPH_03288 7.43e-313 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
HAMMFLPH_03289 3.82e-183 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HAMMFLPH_03290 5.44e-81 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HAMMFLPH_03291 1.01e-189 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
HAMMFLPH_03292 6.5e-126 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
HAMMFLPH_03293 2.15e-236 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HAMMFLPH_03294 1.53e-74 yusD - - S - - - SCP-2 sterol transfer family
HAMMFLPH_03295 2e-73 yusE - - CO - - - Thioredoxin
HAMMFLPH_03296 1.32e-97 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
HAMMFLPH_03297 7.34e-54 yusG - - S - - - Protein of unknown function (DUF2553)
HAMMFLPH_03298 5.91e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
HAMMFLPH_03299 1.01e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
HAMMFLPH_03300 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
HAMMFLPH_03301 1.34e-278 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
HAMMFLPH_03302 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
HAMMFLPH_03303 2.86e-14 - - - S - - - YuzL-like protein
HAMMFLPH_03304 2.09e-212 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
HAMMFLPH_03305 2.23e-54 - - - - - - - -
HAMMFLPH_03306 2.12e-70 yusN - - M - - - Coat F domain
HAMMFLPH_03307 3.83e-99 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
HAMMFLPH_03308 0.0 yusP - - P - - - Major facilitator superfamily
HAMMFLPH_03309 1.76e-86 yusQ - - S - - - Tautomerase enzyme
HAMMFLPH_03310 6.81e-82 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
HAMMFLPH_03311 4.48e-67 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
HAMMFLPH_03312 1.52e-206 gltR - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
HAMMFLPH_03313 3.66e-64 yusU - - S - - - Protein of unknown function (DUF2573)
HAMMFLPH_03314 1.06e-196 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HAMMFLPH_03315 2.01e-87 - - - S - - - YusW-like protein
HAMMFLPH_03316 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
HAMMFLPH_03317 1.21e-41 pepF2 - - E - - - COG1164 Oligoendopeptidase F
HAMMFLPH_03318 6.65e-198 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HAMMFLPH_03319 1.07e-104 fri - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
HAMMFLPH_03320 7.9e-305 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HAMMFLPH_03321 2.23e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HAMMFLPH_03322 0.0 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HAMMFLPH_03323 3.06e-204 yuxN - - K - - - Transcriptional regulator
HAMMFLPH_03324 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HAMMFLPH_03325 4.48e-34 - - - S - - - Protein of unknown function (DUF3970)
HAMMFLPH_03326 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
HAMMFLPH_03327 2.9e-253 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
HAMMFLPH_03328 3.48e-249 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
HAMMFLPH_03329 9.39e-141 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HAMMFLPH_03330 4.06e-246 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HAMMFLPH_03331 5.39e-164 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
HAMMFLPH_03332 6.57e-178 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
HAMMFLPH_03333 4.22e-144 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
HAMMFLPH_03334 1.51e-82 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
HAMMFLPH_03335 1.13e-288 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
HAMMFLPH_03336 8.21e-133 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
HAMMFLPH_03337 0.0 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HAMMFLPH_03338 3.29e-237 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HAMMFLPH_03339 5.15e-219 btuF - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
HAMMFLPH_03340 5.21e-182 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HAMMFLPH_03341 1.32e-219 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
HAMMFLPH_03342 0.0 yvrG - - T - - - Histidine kinase
HAMMFLPH_03343 2.08e-169 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HAMMFLPH_03344 5.07e-32 - - - - - - - -
HAMMFLPH_03345 6.74e-126 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
HAMMFLPH_03346 3.46e-26 - - - S - - - YvrJ protein family
HAMMFLPH_03347 1.59e-292 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
HAMMFLPH_03348 9.89e-86 yvrL - - S - - - Regulatory protein YrvL
HAMMFLPH_03349 1.17e-272 yvrN - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
HAMMFLPH_03350 1.62e-159 yvrO - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HAMMFLPH_03351 3.61e-231 - - - M ko:K02005 - ko00000 Efflux transporter rnd family, mfp subunit
HAMMFLPH_03352 2.92e-191 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HAMMFLPH_03353 4.78e-226 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HAMMFLPH_03354 1.48e-237 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HAMMFLPH_03355 1.14e-227 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HAMMFLPH_03357 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
HAMMFLPH_03358 9.37e-23 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
HAMMFLPH_03359 2.38e-109 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
HAMMFLPH_03360 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
HAMMFLPH_03361 5.58e-218 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
HAMMFLPH_03362 6.57e-179 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
HAMMFLPH_03363 6.08e-154 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
HAMMFLPH_03364 4.54e-203 yvgN - - S - - - reductase
HAMMFLPH_03365 7.97e-113 yvgO - - - - - - -
HAMMFLPH_03366 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
HAMMFLPH_03367 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HAMMFLPH_03368 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HAMMFLPH_03369 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
HAMMFLPH_03370 3.88e-140 yvgT - - S - - - membrane
HAMMFLPH_03371 1.99e-95 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
HAMMFLPH_03372 3.45e-137 bdbD - - O - - - Thioredoxin
HAMMFLPH_03373 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
HAMMFLPH_03374 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
HAMMFLPH_03375 3.66e-41 copZ - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Copper resistance protein CopZ
HAMMFLPH_03376 6.89e-65 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
HAMMFLPH_03377 7.89e-254 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
HAMMFLPH_03378 3.59e-154 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HAMMFLPH_03379 0.0 - - - S - - - Fusaric acid resistance protein-like
HAMMFLPH_03380 2.02e-97 yvaD - - S - - - Family of unknown function (DUF5360)
HAMMFLPH_03381 4.28e-72 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
HAMMFLPH_03382 8.9e-131 - - - K - - - Bacterial regulatory proteins, tetR family
HAMMFLPH_03383 3.96e-182 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
HAMMFLPH_03385 2.4e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HAMMFLPH_03386 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HAMMFLPH_03387 3.43e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
HAMMFLPH_03388 1.87e-35 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
HAMMFLPH_03389 4.03e-196 yvaM 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Serine aminopeptidase, S33
HAMMFLPH_03390 3.44e-48 yvzC - - K - - - transcriptional
HAMMFLPH_03391 4.08e-92 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
HAMMFLPH_03392 1.19e-92 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
HAMMFLPH_03393 3.85e-72 yvaP - - K - - - transcriptional
HAMMFLPH_03394 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HAMMFLPH_03395 2.26e-144 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
HAMMFLPH_03396 2.89e-221 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HAMMFLPH_03397 1.55e-142 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
HAMMFLPH_03398 6.29e-272 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HAMMFLPH_03399 1.15e-122 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
HAMMFLPH_03400 2.75e-11 - - - S - - - Sporulation delaying protein SdpA
HAMMFLPH_03401 4.79e-224 - - - - - - - -
HAMMFLPH_03403 8.32e-133 yvaZ - - S - - - Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
HAMMFLPH_03404 9.63e-60 sdpR - - K - - - transcriptional
HAMMFLPH_03405 6.75e-146 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
HAMMFLPH_03406 2.58e-223 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HAMMFLPH_03407 5.63e-145 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
HAMMFLPH_03408 5.58e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HAMMFLPH_03409 1.74e-130 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
HAMMFLPH_03410 9.68e-136 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
HAMMFLPH_03411 1.03e-145 yvbH - - S - - - YvbH-like oligomerisation region
HAMMFLPH_03412 2.38e-158 yvbI - - M - - - Membrane
HAMMFLPH_03413 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
HAMMFLPH_03414 2.4e-106 yvbK - - K - - - acetyltransferase
HAMMFLPH_03415 1.38e-309 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HAMMFLPH_03416 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
HAMMFLPH_03417 2.12e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HAMMFLPH_03418 1.97e-277 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
HAMMFLPH_03419 5.72e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HAMMFLPH_03420 2.42e-237 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HAMMFLPH_03421 0.0 araE - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HAMMFLPH_03422 1.51e-258 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
HAMMFLPH_03423 1.04e-245 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HAMMFLPH_03424 3.45e-206 yvbU - - K - - - Transcriptional regulator
HAMMFLPH_03425 2.37e-199 yvbV - - EG - - - EamA-like transporter family
HAMMFLPH_03426 7.07e-307 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
HAMMFLPH_03427 2.68e-252 - - - S - - - Glycosyl hydrolase
HAMMFLPH_03428 1.45e-172 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HAMMFLPH_03429 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
HAMMFLPH_03430 5.47e-176 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HAMMFLPH_03431 7.53e-137 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HAMMFLPH_03432 1.76e-257 yvfT 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HAMMFLPH_03433 2.48e-171 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
HAMMFLPH_03434 1.03e-209 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
HAMMFLPH_03435 7.25e-201 rsbQ - - S ko:K19707 - ko00000,ko03021 Alpha/beta hydrolase family
HAMMFLPH_03436 1.52e-265 - 3.1.3.3 - T ko:K07315 - ko00000,ko01000,ko03021 response regulator
HAMMFLPH_03437 0.0 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
HAMMFLPH_03438 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 beta-galactosidase
HAMMFLPH_03439 3.82e-194 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
HAMMFLPH_03440 1.3e-301 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
HAMMFLPH_03441 2.05e-295 cycB - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
HAMMFLPH_03442 6.42e-237 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HAMMFLPH_03443 6.85e-146 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
HAMMFLPH_03444 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
HAMMFLPH_03445 2.57e-308 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
HAMMFLPH_03446 5.69e-44 yvfG - - S - - - YvfG protein
HAMMFLPH_03447 1.85e-241 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
HAMMFLPH_03448 1.2e-284 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
HAMMFLPH_03449 6.53e-81 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
HAMMFLPH_03450 1.65e-141 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HAMMFLPH_03451 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HAMMFLPH_03452 4.44e-251 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
HAMMFLPH_03453 5.09e-264 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
HAMMFLPH_03454 6.3e-251 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
HAMMFLPH_03455 8.82e-265 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
HAMMFLPH_03456 7.49e-280 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HAMMFLPH_03457 2.16e-202 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
HAMMFLPH_03458 2.95e-286 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
HAMMFLPH_03459 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
HAMMFLPH_03460 7.94e-150 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
HAMMFLPH_03461 2.78e-158 epsA - - M ko:K19420 - ko00000 biosynthesis protein
HAMMFLPH_03462 2.15e-99 - - - K ko:K19417 - ko00000,ko03000 transcriptional
HAMMFLPH_03463 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
HAMMFLPH_03465 5.4e-120 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
HAMMFLPH_03466 5.1e-64 - - - S - - - Protein of unknown function (DUF3237)
HAMMFLPH_03467 1.51e-163 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
HAMMFLPH_03468 0.0 pbpE - - V - - - Beta-lactamase
HAMMFLPH_03469 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
HAMMFLPH_03470 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
HAMMFLPH_03471 0.0 ybeC - - E - - - amino acid
HAMMFLPH_03472 1.17e-137 yvdT_1 - - K - - - Transcriptional regulator
HAMMFLPH_03473 6.31e-68 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
HAMMFLPH_03474 1.03e-66 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
HAMMFLPH_03475 5.53e-122 yvdQ - - S - - - Protein of unknown function (DUF3231)
HAMMFLPH_03476 0.0 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
HAMMFLPH_03477 1.99e-235 - - - S - - - Patatin-like phospholipase
HAMMFLPH_03479 8.17e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HAMMFLPH_03480 1.01e-156 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
HAMMFLPH_03481 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
HAMMFLPH_03482 0.0 yvdK 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
HAMMFLPH_03483 2.42e-203 malA - - S - - - Protein of unknown function (DUF1189)
HAMMFLPH_03484 1.18e-190 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
HAMMFLPH_03485 2.12e-311 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
HAMMFLPH_03486 1.03e-302 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
HAMMFLPH_03487 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, N-terminal ig-like domain
HAMMFLPH_03488 2.28e-223 yvdE - - K - - - Transcriptional regulator
HAMMFLPH_03489 2.66e-137 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
HAMMFLPH_03490 7.84e-71 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
HAMMFLPH_03491 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
HAMMFLPH_03492 3.73e-137 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
HAMMFLPH_03493 1.4e-235 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HAMMFLPH_03494 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
HAMMFLPH_03495 4.46e-181 yxdL_2 - - V ko:K02003,ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HAMMFLPH_03496 1.68e-252 yvcQ - - T - - - His Kinase A (phosphoacceptor) domain
HAMMFLPH_03497 4.67e-172 yvcP - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HAMMFLPH_03498 1.37e-45 - - - - - - - -
HAMMFLPH_03499 5.24e-188 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
HAMMFLPH_03500 3.92e-50 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
HAMMFLPH_03501 3.63e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
HAMMFLPH_03502 6.72e-227 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
HAMMFLPH_03503 2.09e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
HAMMFLPH_03504 2.39e-117 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HAMMFLPH_03505 8.31e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HAMMFLPH_03506 3.05e-190 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
HAMMFLPH_03507 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
HAMMFLPH_03508 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
HAMMFLPH_03510 0.0 - - - - - - - -
HAMMFLPH_03511 6.36e-172 - - - - - - - -
HAMMFLPH_03512 2.61e-146 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
HAMMFLPH_03513 9.74e-177 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HAMMFLPH_03514 1.44e-170 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HAMMFLPH_03515 7.21e-150 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HAMMFLPH_03516 4.96e-139 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
HAMMFLPH_03517 1.19e-297 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HAMMFLPH_03518 9.09e-149 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HAMMFLPH_03519 2.07e-282 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HAMMFLPH_03520 2.14e-179 yvpB - - NU - - - protein conserved in bacteria
HAMMFLPH_03521 5.68e-156 - 4.2.2.10, 4.2.2.2 - G ko:K19551 ko00040,map00040 ko00000,ko00001,ko01000 Pectate lyase
HAMMFLPH_03522 5.29e-121 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
HAMMFLPH_03523 4.51e-155 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HAMMFLPH_03524 3.19e-212 yvoD - - P - - - COG0370 Fe2 transport system protein B
HAMMFLPH_03525 3.18e-195 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HAMMFLPH_03526 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HAMMFLPH_03527 2.25e-284 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
HAMMFLPH_03528 1.39e-171 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HAMMFLPH_03529 5.23e-172 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
HAMMFLPH_03530 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
HAMMFLPH_03531 9.4e-110 yvnA - - K - - - helix_turn_helix multiple antibiotic resistance protein
HAMMFLPH_03532 1.61e-293 cypX 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
HAMMFLPH_03533 2.49e-177 yvmC 2.3.2.22 - S ko:K17485 - ko00000,ko01000 Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
HAMMFLPH_03534 6.2e-114 yvmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
HAMMFLPH_03535 4.26e-272 yvmA - - EGP - - - Major Facilitator Superfamily
HAMMFLPH_03536 3.8e-66 yvlD - - S ko:K08972 - ko00000 Membrane
HAMMFLPH_03537 1.5e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
HAMMFLPH_03538 5.8e-221 yvlB - - S - - - Putative adhesin
HAMMFLPH_03539 8.09e-65 yvlA - - - - - - -
HAMMFLPH_03540 2.73e-46 yvkN - - - - - - -
HAMMFLPH_03541 2.57e-104 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HAMMFLPH_03542 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HAMMFLPH_03543 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HAMMFLPH_03544 2.54e-42 csbA - - S - - - protein conserved in bacteria
HAMMFLPH_03545 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
HAMMFLPH_03547 1.43e-131 yvkB - - K - - - Transcriptional regulator
HAMMFLPH_03548 5.47e-298 yvkA - - P - - - -transporter
HAMMFLPH_03549 3.86e-281 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HAMMFLPH_03550 1.38e-73 swrA - - S - - - Swarming motility protein
HAMMFLPH_03551 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
HAMMFLPH_03552 5.45e-199 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HAMMFLPH_03553 1.5e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
HAMMFLPH_03554 3.23e-75 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
HAMMFLPH_03555 6.5e-185 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
HAMMFLPH_03556 2e-232 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HAMMFLPH_03557 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HAMMFLPH_03558 1.73e-132 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HAMMFLPH_03559 9.14e-88 - - - - - - - -
HAMMFLPH_03560 8.69e-09 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
HAMMFLPH_03561 5.15e-91 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
HAMMFLPH_03562 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HAMMFLPH_03563 1.1e-76 flaG - - N ko:K06603 - ko00000,ko02035 flagellar protein FlaG
HAMMFLPH_03564 8.01e-202 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HAMMFLPH_03565 2.58e-41 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HAMMFLPH_03566 1.23e-96 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HAMMFLPH_03567 4.19e-93 yviE - - - - - - -
HAMMFLPH_03568 1.97e-199 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
HAMMFLPH_03569 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
HAMMFLPH_03570 3.5e-102 yvyG - - NOU - - - FlgN protein
HAMMFLPH_03571 1.06e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
HAMMFLPH_03572 1.83e-96 yvyF - - S - - - flagellar protein
HAMMFLPH_03573 9.99e-166 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
HAMMFLPH_03574 1.26e-61 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
HAMMFLPH_03575 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HAMMFLPH_03576 2.15e-199 degV - - S - - - protein conserved in bacteria
HAMMFLPH_03577 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HAMMFLPH_03578 2.94e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HAMMFLPH_03579 2.41e-155 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
HAMMFLPH_03580 3.99e-225 yvhJ - - K - - - Transcriptional regulator
HAMMFLPH_03581 2.1e-231 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
HAMMFLPH_03582 3.3e-303 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
HAMMFLPH_03583 8.42e-187 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
HAMMFLPH_03584 6.04e-149 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
HAMMFLPH_03585 0.0 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
HAMMFLPH_03586 0.0 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HAMMFLPH_03587 8.77e-283 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
HAMMFLPH_03588 2.58e-316 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HAMMFLPH_03589 1.49e-143 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HAMMFLPH_03590 0.0 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
HAMMFLPH_03591 0.0 lytB - - D - - - Stage II sporulation protein
HAMMFLPH_03592 3.26e-50 - - - - - - - -
HAMMFLPH_03593 2.77e-219 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HAMMFLPH_03594 6.61e-278 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HAMMFLPH_03595 1.78e-208 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
HAMMFLPH_03596 0.0 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HAMMFLPH_03597 0.0 - - - M - - - Glycosyltransferase like family 2
HAMMFLPH_03598 5.43e-05 - 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase-like
HAMMFLPH_03599 2.13e-127 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
HAMMFLPH_03600 0.0 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HAMMFLPH_03601 2.06e-194 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
HAMMFLPH_03602 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HAMMFLPH_03603 0.0 tagE 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferase 1 domain A
HAMMFLPH_03604 3.82e-91 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
HAMMFLPH_03605 1.9e-185 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HAMMFLPH_03606 3.8e-273 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HAMMFLPH_03607 0.0 - - - - - - - -
HAMMFLPH_03608 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HAMMFLPH_03609 1.16e-241 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
HAMMFLPH_03610 0.0 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
HAMMFLPH_03611 1.24e-256 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
HAMMFLPH_03612 2.29e-275 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
HAMMFLPH_03613 8.19e-316 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HAMMFLPH_03614 1.48e-222 ywtF_2 - - K - - - Transcriptional regulator
HAMMFLPH_03615 7.24e-205 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
HAMMFLPH_03616 1.37e-304 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HAMMFLPH_03617 2.29e-29 ywtC - - - - - - -
HAMMFLPH_03618 1.33e-277 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
HAMMFLPH_03619 8.44e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
HAMMFLPH_03620 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
HAMMFLPH_03621 2.3e-228 rbsR - - K ko:K02529 - ko00000,ko03000 transcriptional
HAMMFLPH_03622 6.44e-207 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HAMMFLPH_03623 5.6e-85 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HAMMFLPH_03624 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HAMMFLPH_03625 2.87e-204 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HAMMFLPH_03626 1.34e-205 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
HAMMFLPH_03627 2.49e-122 batE - - T - - - Sh3 type 3 domain protein
HAMMFLPH_03628 9.2e-64 ywsA - - S - - - Protein of unknown function (DUF3892)
HAMMFLPH_03629 2.15e-126 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
HAMMFLPH_03630 1.84e-187 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
HAMMFLPH_03631 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
HAMMFLPH_03632 3.36e-218 alsR - - K - - - LysR substrate binding domain
HAMMFLPH_03633 1.68e-281 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HAMMFLPH_03634 9.09e-164 ywrJ - - - - - - -
HAMMFLPH_03635 1.02e-196 cotB - - - ko:K06325 - ko00000 -
HAMMFLPH_03636 1.12e-269 cotH - - M ko:K06330 - ko00000 Spore Coat
HAMMFLPH_03637 2.17e-16 - - - - - - - -
HAMMFLPH_03638 4.35e-143 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HAMMFLPH_03639 2.78e-71 - - - S - - - Domain of unknown function (DUF4181)
HAMMFLPH_03640 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
HAMMFLPH_03641 4.83e-108 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
HAMMFLPH_03642 5.52e-133 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
HAMMFLPH_03643 3.66e-115 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
HAMMFLPH_03645 3.83e-132 ywqN - - S - - - NAD(P)H-dependent
HAMMFLPH_03646 1.16e-209 - - - K - - - Transcriptional regulator
HAMMFLPH_03647 7.78e-176 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
HAMMFLPH_03648 1.36e-71 - - - S - - - MORN repeat variant
HAMMFLPH_03649 0.0 - - - L - - - nucleic acid phosphodiester bond hydrolysis
HAMMFLPH_03650 2.17e-52 ywqI - - S - - - Family of unknown function (DUF5344)
HAMMFLPH_03652 2.52e-197 ywqG - - S - - - Domain of unknown function (DUF1963)
HAMMFLPH_03653 9.82e-315 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HAMMFLPH_03654 3.16e-183 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
HAMMFLPH_03655 4.51e-156 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
HAMMFLPH_03656 5.33e-163 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
HAMMFLPH_03657 3.6e-25 - - - - - - - -
HAMMFLPH_03658 0.0 ywqB - - S - - - SWIM zinc finger
HAMMFLPH_03659 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
HAMMFLPH_03660 4.53e-203 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
HAMMFLPH_03661 4.82e-180 glcR - - K ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
HAMMFLPH_03662 1.04e-76 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
HAMMFLPH_03663 5.26e-88 ywpG - - - - - - -
HAMMFLPH_03664 8.81e-89 ywpF - - S - - - YwpF-like protein
HAMMFLPH_03665 4.63e-68 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
HAMMFLPH_03666 2.55e-197 ywpD - - T - - - Histidine kinase
HAMMFLPH_03667 1.13e-79 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HAMMFLPH_03668 6.89e-107 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HAMMFLPH_03669 5.45e-257 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
HAMMFLPH_03670 4.1e-182 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
HAMMFLPH_03671 6.18e-173 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
HAMMFLPH_03672 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
HAMMFLPH_03673 4.88e-59 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
HAMMFLPH_03674 8.45e-92 - - - K - - - COG1846 Transcriptional regulators
HAMMFLPH_03675 1.37e-269 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
HAMMFLPH_03676 1.02e-312 ywoF - - P - - - Right handed beta helix region
HAMMFLPH_03677 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
HAMMFLPH_03678 8e-309 ywoD - - EGP - - - Major facilitator superfamily
HAMMFLPH_03679 2.56e-134 yjgF - - Q - - - Isochorismatase family
HAMMFLPH_03680 3.04e-102 - - - - - - - -
HAMMFLPH_03681 1.6e-288 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
HAMMFLPH_03682 4.51e-77 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
HAMMFLPH_03683 6.02e-135 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
HAMMFLPH_03684 1.63e-95 ywnJ - - S - - - VanZ like family
HAMMFLPH_03685 2.13e-175 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
HAMMFLPH_03686 1.55e-116 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
HAMMFLPH_03687 3.28e-22 ywnC - - S - - - Family of unknown function (DUF5362)
HAMMFLPH_03688 7.07e-92 ywnF - - S - - - Family of unknown function (DUF5392)
HAMMFLPH_03689 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HAMMFLPH_03690 3.41e-184 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
HAMMFLPH_03691 1.06e-78 ywnC - - S - - - Family of unknown function (DUF5362)
HAMMFLPH_03692 1.29e-148 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
HAMMFLPH_03693 4.58e-85 ywnA - - K - - - Transcriptional regulator
HAMMFLPH_03694 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HAMMFLPH_03695 1.12e-83 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
HAMMFLPH_03696 8.2e-68 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
HAMMFLPH_03698 1.11e-21 csbD - - K - - - CsbD-like
HAMMFLPH_03699 1.12e-109 ywmF - - S - - - Peptidase M50
HAMMFLPH_03700 1.25e-128 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
HAMMFLPH_03701 2.65e-246 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HAMMFLPH_03702 2.22e-187 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HAMMFLPH_03704 1.02e-155 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
HAMMFLPH_03705 1.89e-157 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
HAMMFLPH_03706 3.72e-238 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
HAMMFLPH_03707 4.96e-306 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HAMMFLPH_03708 2.39e-174 ywmB - - S - - - TATA-box binding
HAMMFLPH_03709 4.54e-45 ywzB - - S - - - membrane
HAMMFLPH_03710 6.12e-115 ywmA - - - - - - -
HAMMFLPH_03711 1.04e-76 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
HAMMFLPH_03712 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HAMMFLPH_03713 4.46e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HAMMFLPH_03714 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HAMMFLPH_03715 2.89e-118 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HAMMFLPH_03716 2.62e-79 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HAMMFLPH_03717 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HAMMFLPH_03718 6.06e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
HAMMFLPH_03719 1.91e-81 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
HAMMFLPH_03720 5.5e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HAMMFLPH_03721 4.36e-303 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HAMMFLPH_03722 2.49e-123 ywlG - - S - - - Belongs to the UPF0340 family
HAMMFLPH_03723 2.35e-106 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
HAMMFLPH_03724 5.75e-103 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HAMMFLPH_03725 4.56e-117 mntP - - P - - - Probably functions as a manganese efflux pump
HAMMFLPH_03726 4.44e-252 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HAMMFLPH_03727 1.79e-100 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
HAMMFLPH_03728 1.14e-152 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
HAMMFLPH_03729 1.67e-74 ywlA - - S - - - Uncharacterised protein family (UPF0715)
HAMMFLPH_03731 5.96e-205 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HAMMFLPH_03732 9.95e-245 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HAMMFLPH_03733 1.19e-89 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HAMMFLPH_03734 6.26e-119 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
HAMMFLPH_03735 3.24e-204 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
HAMMFLPH_03736 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
HAMMFLPH_03737 8.53e-136 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
HAMMFLPH_03738 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
HAMMFLPH_03739 5.53e-303 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HAMMFLPH_03740 3.51e-225 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
HAMMFLPH_03741 2.26e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HAMMFLPH_03742 5.69e-147 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HAMMFLPH_03743 7.82e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
HAMMFLPH_03744 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
HAMMFLPH_03745 3.31e-120 ywjG - - S - - - Domain of unknown function (DUF2529)
HAMMFLPH_03746 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HAMMFLPH_03747 1.03e-82 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HAMMFLPH_03748 2.1e-269 acdA - - I - - - acyl-CoA dehydrogenase
HAMMFLPH_03749 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
HAMMFLPH_03750 8.56e-290 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HAMMFLPH_03751 4.88e-236 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
HAMMFLPH_03752 1.32e-57 ywjC - - - - - - -
HAMMFLPH_03753 1.35e-124 ywjB - - H - - - RibD C-terminal domain
HAMMFLPH_03754 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
HAMMFLPH_03755 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HAMMFLPH_03756 1.02e-159 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
HAMMFLPH_03757 6.32e-128 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
HAMMFLPH_03758 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
HAMMFLPH_03759 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HAMMFLPH_03760 8.67e-111 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
HAMMFLPH_03761 1.57e-180 ywiC - - S - - - YwiC-like protein
HAMMFLPH_03762 3.98e-169 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
HAMMFLPH_03763 3.39e-274 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
HAMMFLPH_03764 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
HAMMFLPH_03765 4.64e-96 ywiB - - S - - - protein conserved in bacteria
HAMMFLPH_03766 3.71e-12 - - - S - - - Bacteriocin subtilosin A
HAMMFLPH_03767 0.0 - - - C ko:K22227 - ko00000 Fe-S oxidoreductases
HAMMFLPH_03769 1.5e-169 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HAMMFLPH_03770 1.07e-300 mgtA 3.6.3.2 - P ko:K01531,ko:K16905 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPase, P-type transporting, HAD superfamily, subfamily IC
HAMMFLPH_03771 7.55e-280 - 2.7.1.26, 2.7.7.2 - L ko:K07263,ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase, M16
HAMMFLPH_03772 0.0 - - - L - - - Peptidase, M16
HAMMFLPH_03774 0.0 ywhL - - CO - - - amine dehydrogenase activity
HAMMFLPH_03775 2.36e-291 ywhK - - CO - - - amine dehydrogenase activity
HAMMFLPH_03776 2.88e-100 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
HAMMFLPH_03778 6.61e-110 - - - S - - - Aminoacyl-tRNA editing domain
HAMMFLPH_03779 2.1e-215 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
HAMMFLPH_03780 1.93e-204 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HAMMFLPH_03781 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HAMMFLPH_03782 1.92e-123 ywhD - - S - - - YwhD family
HAMMFLPH_03783 3.29e-154 ywhC - - S - - - Peptidase family M50
HAMMFLPH_03784 1.43e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
HAMMFLPH_03785 1.76e-94 ywhA - - K - - - Transcriptional regulator
HAMMFLPH_03786 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HAMMFLPH_03788 2.66e-307 mmr - - U ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
HAMMFLPH_03789 1.1e-103 yffB - - K - - - Transcriptional regulator
HAMMFLPH_03790 1.47e-115 ywgA - - - ko:K09388 - ko00000 -
HAMMFLPH_03791 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
HAMMFLPH_03792 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
HAMMFLPH_03793 5.65e-147 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
HAMMFLPH_03794 1.57e-204 ywfM - - EG ko:K03298 - ko00000,ko02000 EamA-like transporter family
HAMMFLPH_03795 2.15e-199 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HAMMFLPH_03796 9.56e-212 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
HAMMFLPH_03797 7.1e-226 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
HAMMFLPH_03798 3.43e-187 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
HAMMFLPH_03799 3.52e-178 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
HAMMFLPH_03800 1.89e-298 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
HAMMFLPH_03801 1.36e-268 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
HAMMFLPH_03802 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
HAMMFLPH_03803 1.33e-179 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HAMMFLPH_03804 1.24e-175 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
HAMMFLPH_03805 5.11e-146 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
HAMMFLPH_03806 1.89e-275 ywfA - - EGP - - - -transporter
HAMMFLPH_03807 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
HAMMFLPH_03808 0.0 rocB - - E - - - arginine degradation protein
HAMMFLPH_03809 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
HAMMFLPH_03810 5.19e-311 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
HAMMFLPH_03811 1.1e-102 - - - - - - - -
HAMMFLPH_03812 9.16e-114 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
HAMMFLPH_03813 2.44e-206 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HAMMFLPH_03814 9.08e-234 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HAMMFLPH_03815 2.6e-178 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HAMMFLPH_03816 2.54e-243 spsG - - M - - - Spore Coat
HAMMFLPH_03817 4.64e-169 spsF - - M ko:K07257 - ko00000 Spore Coat
HAMMFLPH_03818 6.8e-272 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
HAMMFLPH_03819 1.04e-210 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
HAMMFLPH_03820 4.54e-285 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
HAMMFLPH_03821 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
HAMMFLPH_03822 4.87e-188 spsA - - M - - - Spore Coat
HAMMFLPH_03823 7.61e-114 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HAMMFLPH_03824 1.59e-78 ywdK - - S - - - small membrane protein
HAMMFLPH_03825 4.57e-304 ywdJ - - F - - - Xanthine uracil
HAMMFLPH_03826 9.23e-65 ywdI - - S - - - Family of unknown function (DUF5327)
HAMMFLPH_03827 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HAMMFLPH_03828 2.32e-166 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HAMMFLPH_03829 5.69e-193 ywdF - - S - - - Glycosyltransferase like family 2
HAMMFLPH_03831 8.74e-146 ywdD - - - - - - -
HAMMFLPH_03832 7.92e-76 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
HAMMFLPH_03833 5.43e-188 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HAMMFLPH_03834 6.19e-39 ywdA - - - - - - -
HAMMFLPH_03835 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
HAMMFLPH_03836 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HAMMFLPH_03837 2.91e-180 - - - P ko:K02598 - ko00000,ko02000 Formate/nitrite transporter
HAMMFLPH_03838 4.49e-194 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
HAMMFLPH_03840 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HAMMFLPH_03841 4.19e-239 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HAMMFLPH_03842 1.98e-179 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
HAMMFLPH_03843 8.89e-269 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
HAMMFLPH_03844 6.61e-52 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
HAMMFLPH_03845 1.12e-83 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
HAMMFLPH_03846 1.2e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
HAMMFLPH_03847 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HAMMFLPH_03848 6.94e-226 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HAMMFLPH_03849 5.11e-49 ydaS - - S - - - membrane
HAMMFLPH_03850 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
HAMMFLPH_03851 5.56e-291 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HAMMFLPH_03852 3.33e-77 gtcA - - S - - - GtrA-like protein
HAMMFLPH_03853 4.16e-159 ywcC - - K - - - transcriptional regulator
HAMMFLPH_03855 7.41e-65 ywcB - - S - - - Protein of unknown function, DUF485
HAMMFLPH_03856 0.0 ywcA - - S ko:K14393 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HAMMFLPH_03857 1.08e-145 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
HAMMFLPH_03858 3.23e-310 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
HAMMFLPH_03859 6.21e-249 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
HAMMFLPH_03860 0.0 - - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
HAMMFLPH_03861 7.69e-150 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HAMMFLPH_03862 3.25e-185 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HAMMFLPH_03863 2.7e-203 ywbI - - K - - - Transcriptional regulator
HAMMFLPH_03864 1.1e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
HAMMFLPH_03865 1.21e-143 ywbG - - M - - - effector of murein hydrolase
HAMMFLPH_03866 1.29e-280 ywbF - - EGP ko:K05820 - ko00000,ko02000 Nucleoside H+ symporter
HAMMFLPH_03867 1.32e-39 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
HAMMFLPH_03868 1.3e-283 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
HAMMFLPH_03869 1.99e-87 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
HAMMFLPH_03870 7.78e-165 ywbB - - S - - - Protein of unknown function (DUF2711)
HAMMFLPH_03871 9.36e-317 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HAMMFLPH_03872 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HAMMFLPH_03873 1.45e-312 sacX 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HAMMFLPH_03874 9.07e-196 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
HAMMFLPH_03875 6.53e-217 gspA - - M - - - General stress
HAMMFLPH_03876 3.96e-164 ywaF - - S - - - Integral membrane protein
HAMMFLPH_03877 2.15e-115 ywaE - - K - - - Transcriptional regulator
HAMMFLPH_03878 2.7e-298 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HAMMFLPH_03879 0.0 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
HAMMFLPH_03880 2.52e-149 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
HAMMFLPH_03881 5.1e-213 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
HAMMFLPH_03882 1.27e-20 - - - S - - - D-Ala-teichoic acid biosynthesis protein
HAMMFLPH_03883 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HAMMFLPH_03884 1.14e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
HAMMFLPH_03885 6.83e-50 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HAMMFLPH_03886 4.09e-294 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HAMMFLPH_03887 2.91e-178 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
HAMMFLPH_03888 1.07e-263 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
HAMMFLPH_03889 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HAMMFLPH_03890 8.33e-68 licA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HAMMFLPH_03891 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HAMMFLPH_03892 1.89e-67 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
HAMMFLPH_03893 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
HAMMFLPH_03894 8.94e-28 yxzF - - - - - - -
HAMMFLPH_03895 3.23e-145 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
HAMMFLPH_03896 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
HAMMFLPH_03897 4.48e-277 yxlH - - EGP - - - Major Facilitator Superfamily
HAMMFLPH_03898 3.96e-179 yxlG - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HAMMFLPH_03899 2.09e-213 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HAMMFLPH_03900 2.17e-39 yxlE - - S - - - Phospholipase_D-nuclease N-terminal
HAMMFLPH_03901 1.75e-43 - - - - - - - -
HAMMFLPH_03902 4.05e-64 yxlC - - S - - - Family of unknown function (DUF5345)
HAMMFLPH_03903 9.06e-125 sigY - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HAMMFLPH_03904 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
HAMMFLPH_03905 2.01e-206 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HAMMFLPH_03906 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
HAMMFLPH_03907 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
HAMMFLPH_03908 1.16e-243 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
HAMMFLPH_03909 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
HAMMFLPH_03910 3.97e-310 cimH - - C - - - COG3493 Na citrate symporter
HAMMFLPH_03911 0.0 - - - O - - - Peptidase family M48
HAMMFLPH_03913 1.58e-200 yxkH - - G - - - Polysaccharide deacetylase
HAMMFLPH_03914 3.44e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HAMMFLPH_03915 1.16e-211 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
HAMMFLPH_03916 0.0 aldY 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HAMMFLPH_03917 2.29e-188 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
HAMMFLPH_03918 1.66e-98 yxkC - - S - - - Domain of unknown function (DUF4352)
HAMMFLPH_03919 2.11e-251 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
HAMMFLPH_03920 2.01e-123 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
HAMMFLPH_03921 1.53e-213 - - - K - - - LysR substrate binding domain
HAMMFLPH_03922 5.63e-102 - - - S - - - Protein of unknown function (DUF1453)
HAMMFLPH_03923 7.13e-261 - - - T - - - Signal transduction histidine kinase
HAMMFLPH_03924 5.66e-150 - - - K ko:K02479 - ko00000,ko02022 helix_turn_helix, Lux Regulon
HAMMFLPH_03925 7.76e-299 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
HAMMFLPH_03928 2.57e-114 yxjI - - S - - - LURP-one-related
HAMMFLPH_03929 7.74e-280 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
HAMMFLPH_03930 9.77e-279 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
HAMMFLPH_03931 5.83e-176 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HAMMFLPH_03932 5.91e-151 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HAMMFLPH_03933 4.65e-168 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HAMMFLPH_03934 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
HAMMFLPH_03935 4.24e-186 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
HAMMFLPH_03936 2.1e-269 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HAMMFLPH_03937 2.96e-29 - - - T - - - Domain of unknown function (DUF4163)
HAMMFLPH_03938 9.65e-65 yxiS - - - - - - -
HAMMFLPH_03939 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
HAMMFLPH_03940 2e-284 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
HAMMFLPH_03941 2.62e-185 bglS - - M - - - licheninase activity
HAMMFLPH_03942 5.66e-193 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
HAMMFLPH_03943 2.75e-145 - - - - - - - -
HAMMFLPH_03944 3.97e-294 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
HAMMFLPH_03945 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
HAMMFLPH_03946 3.28e-279 - - - E - - - GDSL-like Lipase/Acylhydrolase
HAMMFLPH_03949 5.53e-65 yxiJ - - S - - - YxiJ-like protein
HAMMFLPH_03950 3.79e-125 yxiI - - S - - - Protein of unknown function (DUF2716)
HAMMFLPH_03951 6.22e-107 - - - - - - - -
HAMMFLPH_03952 1.2e-57 - - - - - - - -
HAMMFLPH_03953 8.76e-99 yxiG - - - - - - -
HAMMFLPH_03954 1.12e-82 - - - - - - - -
HAMMFLPH_03955 3.69e-111 - - - - - - - -
HAMMFLPH_03956 1.09e-94 yxxG - - - - - - -
HAMMFLPH_03957 0.0 wapA - - M - - - COG3209 Rhs family protein
HAMMFLPH_03958 1.36e-215 yxxF - - EG - - - EamA-like transporter family
HAMMFLPH_03959 8.5e-95 yxiE - - T - - - Belongs to the universal stress protein A family
HAMMFLPH_03960 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HAMMFLPH_03961 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HAMMFLPH_03962 1.33e-67 - - - - - - - -
HAMMFLPH_03963 9.25e-103 - - - S ko:K21494 - ko00000,ko02048 SMI1 / KNR4 family
HAMMFLPH_03964 0.0 - - - S ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
HAMMFLPH_03965 2.3e-53 yxiC - - S - - - Family of unknown function (DUF5344)
HAMMFLPH_03966 1.88e-37 - - - S - - - Domain of unknown function (DUF5082)
HAMMFLPH_03967 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
HAMMFLPH_03968 7.02e-103 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
HAMMFLPH_03969 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
HAMMFLPH_03970 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HAMMFLPH_03971 2.44e-303 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
HAMMFLPH_03972 4.15e-232 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
HAMMFLPH_03973 0.0 ybgF - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
HAMMFLPH_03974 4.9e-300 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
HAMMFLPH_03975 1.92e-263 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HAMMFLPH_03976 1.44e-150 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HAMMFLPH_03977 4.26e-222 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HAMMFLPH_03978 9.11e-198 - - - S - - - Domain of Unknown Function (DUF1206)
HAMMFLPH_03979 4.86e-259 eutH - - E ko:K04023 - ko00000 Ethanolamine utilisation protein, EutH
HAMMFLPH_03980 0.0 yxeQ - - S - - - MmgE/PrpD family
HAMMFLPH_03981 5.21e-275 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
HAMMFLPH_03982 1.67e-171 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HAMMFLPH_03983 1.81e-149 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
HAMMFLPH_03984 4.3e-186 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
HAMMFLPH_03985 1.54e-121 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HAMMFLPH_03986 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HAMMFLPH_03988 2.17e-243 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
HAMMFLPH_03989 1.4e-194 yxeH - - S - - - hydrolases of the HAD superfamily
HAMMFLPH_03992 7.32e-42 yxeE - - - - - - -
HAMMFLPH_03993 2.66e-28 yxeD - - - - - - -
HAMMFLPH_03994 6.79e-91 - - - - - - - -
HAMMFLPH_03995 9.01e-228 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HAMMFLPH_03996 5.95e-77 yxeA - - S - - - Protein of unknown function (DUF1093)
HAMMFLPH_03997 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
HAMMFLPH_03998 9.39e-182 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HAMMFLPH_03999 4e-233 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HAMMFLPH_04000 2.8e-160 yxdJ - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HAMMFLPH_04001 2.43e-205 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
HAMMFLPH_04002 9.32e-188 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
HAMMFLPH_04003 1.87e-213 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
HAMMFLPH_04004 1.55e-251 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HAMMFLPH_04005 1.46e-298 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
HAMMFLPH_04006 4.27e-223 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HAMMFLPH_04007 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HAMMFLPH_04008 2.13e-228 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HAMMFLPH_04009 1.46e-201 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HAMMFLPH_04010 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HAMMFLPH_04011 1.56e-177 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
HAMMFLPH_04012 1.74e-224 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
HAMMFLPH_04014 2.13e-64 yxcD - - S - - - Protein of unknown function (DUF2653)
HAMMFLPH_04015 1.77e-314 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HAMMFLPH_04016 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
HAMMFLPH_04018 4.33e-195 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
HAMMFLPH_04019 3.66e-275 yxbF - - K - - - Bacterial regulatory proteins, tetR family
HAMMFLPH_04020 1.21e-315 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HAMMFLPH_04021 6.59e-111 yxbD 3.2.2.20 - K ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Acetyltransferase (GNAT) domain
HAMMFLPH_04022 1.16e-239 - - - S - - - A domain family that is part of the cupin metalloenzyme superfamily.
HAMMFLPH_04023 1.29e-177 yxbB - - Q - - - Met-10+ like-protein
HAMMFLPH_04024 3.65e-59 - - - S - - - Coenzyme PQQ synthesis protein D (PqqD)
HAMMFLPH_04025 8.99e-114 yxnB - - - - - - -
HAMMFLPH_04026 0.0 - 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
HAMMFLPH_04027 1.8e-271 yxaM - - U - - - MFS_1 like family
HAMMFLPH_04028 2.63e-137 yxaL - - S - - - PQQ-like domain
HAMMFLPH_04029 1.43e-85 - - - S - - - Family of unknown function (DUF5391)
HAMMFLPH_04030 2.83e-99 yxaI - - S - - - membrane protein domain
HAMMFLPH_04031 2.88e-290 - - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
HAMMFLPH_04032 9.33e-254 - 1.13.11.24 - S ko:K07155 - ko00000,ko01000 AraC-like ligand binding domain
HAMMFLPH_04033 9.61e-131 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
HAMMFLPH_04034 4.48e-257 yxnA - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HAMMFLPH_04035 6.83e-94 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HAMMFLPH_04036 2.53e-78 - - - S ko:K06518 - ko00000,ko02000 LrgA family
HAMMFLPH_04037 2.19e-153 yxaC - - M - - - effector of murein hydrolase
HAMMFLPH_04038 1.79e-245 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
HAMMFLPH_04039 2.54e-267 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
HAMMFLPH_04040 4.42e-164 gntR - - K ko:K11476 - ko00000,ko03000 transcriptional
HAMMFLPH_04041 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
HAMMFLPH_04042 2.05e-295 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
HAMMFLPH_04043 0.0 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HAMMFLPH_04044 9.33e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
HAMMFLPH_04045 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
HAMMFLPH_04046 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HAMMFLPH_04047 1.2e-23 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HAMMFLPH_04048 6.34e-165 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
HAMMFLPH_04049 1.44e-24 - - - - - - - -
HAMMFLPH_04050 4.04e-154 - - - S ko:K16916 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
HAMMFLPH_04051 5.06e-144 - - - P ko:K16917 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HAMMFLPH_04052 1.55e-173 - - - O ko:K16922 - ko00000,ko01002 Peptidase M50
HAMMFLPH_04053 1.35e-237 - - - S - - - Radical SAM superfamily
HAMMFLPH_04054 1.99e-17 - - - - - - - -
HAMMFLPH_04055 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
HAMMFLPH_04056 0.0 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2326)
HAMMFLPH_04057 7.17e-86 - - - - - - - -
HAMMFLPH_04058 0.0 - - - S - - - Calcineurin-like phosphoesterase
HAMMFLPH_04059 1.23e-106 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HAMMFLPH_04061 1.25e-93 - - - - - - - -
HAMMFLPH_04062 1.81e-297 yycR 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HAMMFLPH_04064 1.7e-45 yycQ - - S - - - Protein of unknown function (DUF2651)
HAMMFLPH_04065 1.77e-281 yycP - - - - - - -
HAMMFLPH_04066 1.68e-169 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HAMMFLPH_04067 3.84e-113 yycN - - K - - - Acetyltransferase
HAMMFLPH_04068 3.03e-239 - - - S - - - aspartate phosphatase
HAMMFLPH_04070 3.22e-213 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
HAMMFLPH_04071 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
HAMMFLPH_04072 1.5e-296 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
HAMMFLPH_04073 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HAMMFLPH_04074 2.42e-281 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HAMMFLPH_04075 4.01e-191 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
HAMMFLPH_04076 1.2e-200 yycI - - S - - - protein conserved in bacteria
HAMMFLPH_04077 0.0 yycH - - S - - - protein conserved in bacteria
HAMMFLPH_04078 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HAMMFLPH_04079 1.45e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HAMMFLPH_04084 6.38e-315 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HAMMFLPH_04085 1.19e-101 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HAMMFLPH_04086 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
HAMMFLPH_04087 3.48e-40 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
HAMMFLPH_04089 1.89e-22 yycC - - K - - - YycC-like protein
HAMMFLPH_04090 4.19e-283 yycB - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
HAMMFLPH_04091 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HAMMFLPH_04092 2.74e-96 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
HAMMFLPH_04093 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
HAMMFLPH_04094 7.43e-205 yybS - - S - - - membrane
HAMMFLPH_04096 2.89e-110 cotF - - M ko:K06329 - ko00000 Spore coat protein
HAMMFLPH_04097 6.68e-90 yybR - - K - - - Transcriptional regulator
HAMMFLPH_04098 4.89e-210 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
HAMMFLPH_04099 2.34e-92 - - - - - - - -
HAMMFLPH_04101 6.8e-308 yybO - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HAMMFLPH_04102 3.44e-22 - - - - - - - -
HAMMFLPH_04103 1.61e-102 yybN - - S - - - Protein of unknown function (DUF2712)
HAMMFLPH_04104 3.78e-169 - - - - - - - -
HAMMFLPH_04105 5.36e-157 - - - - - - - -
HAMMFLPH_04106 2.34e-163 - - - S - - - Protein of unknown function (DUF2705)
HAMMFLPH_04107 1.14e-149 yybJ - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HAMMFLPH_04108 4.35e-194 - - - - - - - -
HAMMFLPH_04109 3.02e-88 - - - S - - - SnoaL-like domain
HAMMFLPH_04110 1.46e-164 yybG - - S - - - Pentapeptide repeat-containing protein
HAMMFLPH_04111 3.31e-281 yybF - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HAMMFLPH_04112 1.36e-212 yybE - - K - - - Transcriptional regulator
HAMMFLPH_04113 7.91e-104 yjcF - - S - - - Acetyltransferase (GNAT) domain
HAMMFLPH_04114 1.27e-99 yybC - - - - - - -
HAMMFLPH_04115 5.29e-165 - - - S - - - Metallo-beta-lactamase superfamily
HAMMFLPH_04116 4.54e-100 yybA - - K - - - transcriptional
HAMMFLPH_04117 2.45e-103 yjcF - - S - - - Acetyltransferase (GNAT) domain
HAMMFLPH_04118 8.73e-132 yyaS - - S ko:K07149 - ko00000 Membrane
HAMMFLPH_04119 4.03e-130 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
HAMMFLPH_04120 1.09e-87 - - - S - - - YjbR
HAMMFLPH_04121 2.2e-139 yyaP - - H - - - RibD C-terminal domain
HAMMFLPH_04122 0.0 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 COG0477 Permeases of the major facilitator superfamily
HAMMFLPH_04123 1.46e-58 yyaL - - O ko:K06888 - ko00000 Highly conserved protein containing a thioredoxin domain
HAMMFLPH_04124 1.34e-88 - - - K - - - MerR HTH family regulatory protein
HAMMFLPH_04125 1.99e-207 - - - EG - - - EamA-like transporter family
HAMMFLPH_04126 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
HAMMFLPH_04127 8.91e-217 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
HAMMFLPH_04128 0.0 - - - EGP ko:K08369 - ko00000,ko02000 Major facilitator superfamily
HAMMFLPH_04129 1.14e-130 vatD 2.3.1.28, 2.3.1.79 - S ko:K00638,ko:K00661,ko:K18234 - br01600,ko00000,ko01000,ko01504 Bacterial transferase hexapeptide (six repeats)
HAMMFLPH_04130 7.2e-90 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HAMMFLPH_04131 3.03e-230 ccpB - - K - - - Transcriptional regulator
HAMMFLPH_04132 2.07e-187 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
HAMMFLPH_04133 4.25e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HAMMFLPH_04134 1.81e-103 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HAMMFLPH_04135 1.01e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
HAMMFLPH_04136 5.65e-256 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HAMMFLPH_04137 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HAMMFLPH_04138 7.41e-45 yyzM - - S - - - protein conserved in bacteria
HAMMFLPH_04139 5.34e-227 yyaD - - S - - - Membrane
HAMMFLPH_04140 9.15e-145 yyaC - - S - - - Sporulation protein YyaC
HAMMFLPH_04141 3.96e-191 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HAMMFLPH_04142 4.79e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
HAMMFLPH_04143 1.13e-98 - - - S - - - Bacterial PH domain
HAMMFLPH_04144 9e-193 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HAMMFLPH_04145 8.68e-169 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HAMMFLPH_04146 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HAMMFLPH_04147 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HAMMFLPH_04148 1.83e-141 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
HAMMFLPH_04149 9.29e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HAMMFLPH_04150 5.7e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)