ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
NNCLEEBI_00002 3.12e-60 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
NNCLEEBI_00003 1.11e-145 - - - L ko:K07484 - ko00000 Transposase IS66 family
NNCLEEBI_00004 2.49e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NNCLEEBI_00005 2.05e-249 - - - E ko:K03294 - ko00000 amino acid
NNCLEEBI_00006 6.25e-78 pat 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
NNCLEEBI_00007 2.74e-145 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
NNCLEEBI_00008 1.86e-73 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NNCLEEBI_00009 8.12e-37 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
NNCLEEBI_00010 1.32e-55 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
NNCLEEBI_00011 9.04e-263 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NNCLEEBI_00012 6.15e-53 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NNCLEEBI_00013 2.77e-188 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NNCLEEBI_00014 3.3e-286 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
NNCLEEBI_00015 7.23e-130 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NNCLEEBI_00016 9.72e-35 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
NNCLEEBI_00017 3.1e-180 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NNCLEEBI_00018 2.02e-308 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NNCLEEBI_00019 1.21e-302 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
NNCLEEBI_00020 7.35e-69 yloU - - S - - - Asp23 family, cell envelope-related function
NNCLEEBI_00021 1.33e-35 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
NNCLEEBI_00022 1.07e-73 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
NNCLEEBI_00023 3.24e-144 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NNCLEEBI_00024 2.11e-240 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
NNCLEEBI_00025 1.11e-115 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
NNCLEEBI_00026 6.19e-193 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NNCLEEBI_00027 3.64e-176 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NNCLEEBI_00028 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NNCLEEBI_00029 7.57e-153 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NNCLEEBI_00030 8.22e-30 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NNCLEEBI_00031 8.34e-132 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
NNCLEEBI_00032 1.09e-119 - - - M - - - Phosphotransferase enzyme family
NNCLEEBI_00033 4.89e-36 spxA 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
NNCLEEBI_00034 5.18e-235 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
NNCLEEBI_00035 1.34e-20 - - - S - - - Protein of unknown function (DUF2969)
NNCLEEBI_00036 2.29e-36 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
NNCLEEBI_00037 2.82e-214 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
NNCLEEBI_00038 2.43e-261 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NNCLEEBI_00039 8.32e-21 ywzB - - S - - - Protein of unknown function (DUF1146)
NNCLEEBI_00040 6.22e-70 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
NNCLEEBI_00041 8.04e-313 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NNCLEEBI_00042 8.1e-182 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NNCLEEBI_00043 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NNCLEEBI_00044 2.82e-74 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NNCLEEBI_00045 2.96e-57 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NNCLEEBI_00046 1.39e-27 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NNCLEEBI_00047 2.33e-124 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
NNCLEEBI_00048 6.26e-129 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NNCLEEBI_00049 4.69e-172 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NNCLEEBI_00050 3.73e-114 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NNCLEEBI_00051 1.04e-230 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NNCLEEBI_00052 1.41e-111 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
NNCLEEBI_00053 8.5e-277 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
NNCLEEBI_00054 4.63e-141 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
NNCLEEBI_00055 2.17e-140 ampC - - V - - - Beta-lactamase
NNCLEEBI_00056 7.43e-41 - - - - - - - -
NNCLEEBI_00057 7.44e-153 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NNCLEEBI_00058 2.86e-256 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NNCLEEBI_00061 1.08e-118 tnp2 - - L - - - Transposase
NNCLEEBI_00062 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NNCLEEBI_00063 5.74e-218 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NNCLEEBI_00064 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
NNCLEEBI_00065 3.65e-75 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NNCLEEBI_00066 1.51e-165 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NNCLEEBI_00067 1.39e-119 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
NNCLEEBI_00068 2.86e-152 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NNCLEEBI_00069 6.33e-74 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NNCLEEBI_00070 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NNCLEEBI_00071 3.59e-34 ylxQ - - J - - - ribosomal protein
NNCLEEBI_00072 3.32e-53 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
NNCLEEBI_00073 1.25e-216 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
NNCLEEBI_00074 1.16e-85 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
NNCLEEBI_00075 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NNCLEEBI_00076 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NNCLEEBI_00077 1.78e-196 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
NNCLEEBI_00078 1.58e-131 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
NNCLEEBI_00079 4.05e-134 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NNCLEEBI_00080 8.26e-105 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NNCLEEBI_00081 1.02e-147 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
NNCLEEBI_00082 8.28e-64 manO - - S - - - Domain of unknown function (DUF956)
NNCLEEBI_00083 4.04e-45 - 2.1.1.63 - H ko:K00567 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NNCLEEBI_00084 5.37e-119 tnp2 - - L - - - Transposase
NNCLEEBI_00086 3.28e-312 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
NNCLEEBI_00087 1.3e-59 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 Transcriptional regulator
NNCLEEBI_00088 3.15e-257 ynbB - - P - - - aluminum resistance
NNCLEEBI_00089 4.29e-141 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NNCLEEBI_00090 6.17e-24 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
NNCLEEBI_00091 2.92e-60 yqhL - - P - - - Rhodanese-like protein
NNCLEEBI_00092 8.22e-203 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
NNCLEEBI_00093 2.47e-34 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
NNCLEEBI_00094 3.18e-90 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
NNCLEEBI_00095 5.52e-51 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NNCLEEBI_00096 7.58e-30 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
NNCLEEBI_00098 2.95e-86 yciQ - - P - - - membrane protein (DUF2207)
NNCLEEBI_00099 1.08e-118 tnp2 - - L - - - Transposase
NNCLEEBI_00100 1.78e-57 - - - S - - - mazG nucleotide pyrophosphohydrolase
NNCLEEBI_00101 1.38e-119 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
NNCLEEBI_00102 3.28e-35 yneF - - S ko:K09976 - ko00000 UPF0154 protein
NNCLEEBI_00103 7.41e-41 ynzC - - S - - - UPF0291 protein
NNCLEEBI_00104 1.29e-106 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NNCLEEBI_00105 1.21e-234 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
NNCLEEBI_00106 5.91e-65 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
NNCLEEBI_00107 2.1e-152 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
NNCLEEBI_00108 1.34e-105 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NNCLEEBI_00109 1.44e-23 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NNCLEEBI_00110 3.28e-181 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NNCLEEBI_00111 3.32e-133 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NNCLEEBI_00112 3.38e-45 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NNCLEEBI_00113 1.4e-60 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
NNCLEEBI_00114 3.77e-123 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NNCLEEBI_00115 1.45e-48 - - - S - - - Protein conserved in bacteria
NNCLEEBI_00116 1.14e-147 - - - - - - - -
NNCLEEBI_00117 4.27e-143 - - - - - - - -
NNCLEEBI_00118 6.74e-170 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
NNCLEEBI_00119 1.6e-24 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
NNCLEEBI_00120 4.16e-152 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NNCLEEBI_00121 1.54e-218 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NNCLEEBI_00122 1.46e-141 csrR - - K - - - response regulator
NNCLEEBI_00124 2.01e-138 - 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NNCLEEBI_00125 3.59e-285 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NNCLEEBI_00126 1.28e-199 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NNCLEEBI_00127 6.6e-76 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NNCLEEBI_00128 4.68e-119 dgk1 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
NNCLEEBI_00129 1.82e-49 - - - - - - - -
NNCLEEBI_00130 7.31e-164 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NNCLEEBI_00131 4.91e-172 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
NNCLEEBI_00132 6.9e-37 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
NNCLEEBI_00133 4.86e-120 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
NNCLEEBI_00134 2.01e-113 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
NNCLEEBI_00135 8.93e-35 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
NNCLEEBI_00136 1.58e-73 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
NNCLEEBI_00137 2.29e-153 ylbM - - S - - - Belongs to the UPF0348 family
NNCLEEBI_00138 1.86e-103 - - - H - - - Nodulation protein S (NodS)
NNCLEEBI_00139 6.84e-66 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NNCLEEBI_00140 6.59e-89 yqeK - - H - - - Hydrolase, HD family
NNCLEEBI_00141 4.98e-99 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NNCLEEBI_00142 9.56e-41 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
NNCLEEBI_00143 1.46e-229 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
NNCLEEBI_00144 7.82e-90 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
NNCLEEBI_00145 5.01e-69 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NNCLEEBI_00146 4.44e-34 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
NNCLEEBI_00147 1.25e-102 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NNCLEEBI_00148 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NNCLEEBI_00149 6.97e-138 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
NNCLEEBI_00150 3.48e-95 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
NNCLEEBI_00151 1.04e-85 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NNCLEEBI_00152 1.23e-61 coaE 2.7.1.24 - H ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NNCLEEBI_00153 5.99e-137 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NNCLEEBI_00154 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NNCLEEBI_00155 1.7e-87 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
NNCLEEBI_00156 6.4e-80 phaJ - - I - - - N-terminal half of MaoC dehydratase
NNCLEEBI_00157 2.49e-282 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
NNCLEEBI_00158 2.35e-296 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
NNCLEEBI_00159 2.88e-96 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NNCLEEBI_00160 1.41e-57 ytpP - - CO - - - Thioredoxin
NNCLEEBI_00161 4.74e-130 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NNCLEEBI_00162 5.58e-124 ytmP - - M - - - Choline/ethanolamine kinase
NNCLEEBI_00163 1.12e-87 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
NNCLEEBI_00164 2.85e-122 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NNCLEEBI_00165 1.1e-68 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
NNCLEEBI_00167 7.01e-144 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NNCLEEBI_00168 1.08e-161 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
NNCLEEBI_00169 2.92e-28 yheA - - S - - - Belongs to the UPF0342 family
NNCLEEBI_00170 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
NNCLEEBI_00172 1.31e-114 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
NNCLEEBI_00173 4.06e-224 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NNCLEEBI_00174 3.44e-92 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NNCLEEBI_00175 3.09e-59 ykuL - - S - - - CBS domain
NNCLEEBI_00176 1.05e-152 gla - - U ko:K02440 - ko00000,ko02000 Major intrinsic protein
NNCLEEBI_00177 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NNCLEEBI_00178 2.1e-305 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
NNCLEEBI_00179 1.89e-291 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NNCLEEBI_00180 7.35e-140 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
NNCLEEBI_00181 3e-130 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
NNCLEEBI_00182 3.3e-160 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NNCLEEBI_00183 5.91e-274 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
NNCLEEBI_00184 3.25e-84 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NNCLEEBI_00185 9.49e-60 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NNCLEEBI_00186 2.87e-247 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NNCLEEBI_00187 3.64e-124 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
NNCLEEBI_00188 6.94e-130 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
NNCLEEBI_00189 1.48e-36 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
NNCLEEBI_00190 6.05e-129 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NNCLEEBI_00191 1.29e-79 - - - K - - - Transcriptional regulator, MarR family
NNCLEEBI_00192 2.66e-86 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NNCLEEBI_00193 1.2e-48 - - - - - - - -
NNCLEEBI_00195 0.0 - - - L - - - Type III restriction enzyme, res subunit
NNCLEEBI_00196 8.65e-72 - 3.1.21.4 - L ko:K01155 - ko00000,ko01000,ko02048 restriction endonuclease
NNCLEEBI_00197 7.15e-79 - - - V - - - site-specific DNA-methyltransferase (adenine-specific) activity
NNCLEEBI_00198 4.38e-242 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
NNCLEEBI_00199 6.3e-104 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NNCLEEBI_00200 1.04e-79 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
NNCLEEBI_00201 4.25e-245 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
NNCLEEBI_00202 9.34e-245 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
NNCLEEBI_00203 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
NNCLEEBI_00204 5.21e-226 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NNCLEEBI_00224 2.55e-65 yugI - - J ko:K07570 - ko00000 general stress protein
NNCLEEBI_00225 1.63e-118 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
NNCLEEBI_00226 3.79e-118 dedA - - S ko:K03975 - ko00000 SNARE associated Golgi protein
NNCLEEBI_00227 4.54e-38 - - - S - - - Protein of unknown function (DUF1461)
NNCLEEBI_00228 1.19e-145 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NNCLEEBI_00229 2.13e-77 yutD - - S - - - Protein of unknown function (DUF1027)
NNCLEEBI_00230 1.06e-71 - - - S - - - Calcineurin-like phosphoesterase
NNCLEEBI_00231 7.42e-240 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
NNCLEEBI_00232 7e-124 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
NNCLEEBI_00236 8.77e-16 - - - - ko:K02246 - ko00000,ko00002,ko02044 -
NNCLEEBI_00237 2.51e-35 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
NNCLEEBI_00238 9.7e-123 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
NNCLEEBI_00239 5.53e-153 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
NNCLEEBI_00240 1.16e-129 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NNCLEEBI_00241 4e-153 yebC - - K - - - Transcriptional regulatory protein
NNCLEEBI_00242 1.19e-54 - - - S - - - VanZ like family
NNCLEEBI_00243 1.26e-202 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
NNCLEEBI_00244 9.17e-219 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
NNCLEEBI_00246 2.23e-10 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NNCLEEBI_00248 3.43e-96 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NNCLEEBI_00249 3.39e-47 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NNCLEEBI_00250 6.12e-83 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
NNCLEEBI_00251 1.97e-53 - - - K - - - Domain of unknown function (DUF1836)
NNCLEEBI_00252 1.1e-106 - - - S - - - membrane
NNCLEEBI_00253 2.8e-100 - - - S - - - VIT family
NNCLEEBI_00254 1.21e-188 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
NNCLEEBI_00255 6.44e-73 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
NNCLEEBI_00256 5.27e-148 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NNCLEEBI_00257 3.54e-145 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NNCLEEBI_00258 1.35e-154 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
NNCLEEBI_00259 5.19e-150 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
NNCLEEBI_00260 1.24e-124 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
NNCLEEBI_00261 1.01e-53 yjbH - - Q - - - Thioredoxin
NNCLEEBI_00262 3.54e-288 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
NNCLEEBI_00263 6.58e-86 coiA - - S ko:K06198 - ko00000 Competence protein
NNCLEEBI_00264 7.64e-62 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NNCLEEBI_00265 7.21e-273 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
NNCLEEBI_00280 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NNCLEEBI_00281 3.45e-36 ykuJ - - S - - - Protein of unknown function (DUF1797)
NNCLEEBI_00282 8.79e-166 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NNCLEEBI_00283 2.25e-164 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
NNCLEEBI_00284 8.96e-204 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
NNCLEEBI_00285 7.6e-119 tnp2 - - L - - - Transposase
NNCLEEBI_00286 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NNCLEEBI_00287 5.69e-49 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
NNCLEEBI_00288 1.5e-22 - - - - - - - -
NNCLEEBI_00289 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
NNCLEEBI_00290 3.55e-31 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
NNCLEEBI_00291 4.68e-131 - - - G - - - MucBP domain
NNCLEEBI_00292 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
NNCLEEBI_00293 2.1e-253 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
NNCLEEBI_00294 3.62e-207 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
NNCLEEBI_00295 4.34e-225 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NNCLEEBI_00296 2.26e-139 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
NNCLEEBI_00297 0.0 lacP - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
NNCLEEBI_00298 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 -beta-galactosidase
NNCLEEBI_00299 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NNCLEEBI_00300 2.79e-146 tagH 3.6.3.40 - GM ko:K01990,ko:K09691,ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NNCLEEBI_00301 3.8e-201 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
NNCLEEBI_00302 1.42e-135 yueF - - S - - - AI-2E family transporter
NNCLEEBI_00303 9.74e-126 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
NNCLEEBI_00304 3.84e-243 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NNCLEEBI_00305 8.86e-79 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
NNCLEEBI_00307 2.22e-30 - - - S - - - Cytochrome B5
NNCLEEBI_00308 7.55e-53 ytlR - - I - - - Diacylglycerol kinase catalytic domain
NNCLEEBI_00309 1.35e-73 - - - - - - - -
NNCLEEBI_00310 4.22e-55 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
NNCLEEBI_00311 6.62e-196 yngD - - S ko:K07097 - ko00000 DHHA1 domain
NNCLEEBI_00312 1.9e-116 yunF - - F - - - Protein of unknown function DUF72
NNCLEEBI_00313 5e-64 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
NNCLEEBI_00315 7.6e-182 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NNCLEEBI_00316 1.5e-40 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NNCLEEBI_00317 3.02e-158 - - - - - - - -
NNCLEEBI_00318 5.03e-83 - - - L ko:K07491 - ko00000 Transposase IS200 like
NNCLEEBI_00319 5.61e-284 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NNCLEEBI_00320 1.63e-224 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NNCLEEBI_00321 1.25e-80 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2263)
NNCLEEBI_00322 2.89e-229 pbuG - - S ko:K06901 - ko00000,ko02000 permease
NNCLEEBI_00324 8.7e-95 - - - S - - - Cell surface protein
NNCLEEBI_00326 0.0 uvrB3 3.1.12.1 - KL ko:K07464 - ko00000,ko01000,ko02048 DEAD_2
NNCLEEBI_00327 6.42e-79 - - - - - - - -
NNCLEEBI_00328 2.05e-55 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
NNCLEEBI_00329 9.6e-241 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NNCLEEBI_00330 4.42e-253 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NNCLEEBI_00333 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NNCLEEBI_00334 1.75e-57 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NNCLEEBI_00335 1.8e-32 ywiB - - S - - - Domain of unknown function (DUF1934)
NNCLEEBI_00336 1e-109 - - - F - - - glutamine amidotransferase
NNCLEEBI_00337 6.95e-261 ywfO - - S ko:K06885 - ko00000 HD domain protein
NNCLEEBI_00338 1.66e-109 - - - S - - - hydrolase
NNCLEEBI_00339 1.52e-96 - - - S ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Putative inner membrane exporter, YdcZ
NNCLEEBI_00340 3.77e-288 - - - L - - - Probable transposase
NNCLEEBI_00341 1.65e-77 - - - - - - - -
NNCLEEBI_00342 1.49e-41 - - - S - - - LlaJI restriction endonuclease
NNCLEEBI_00343 3.75e-80 - - - V - - - AAA domain (dynein-related subfamily)
NNCLEEBI_00344 1.58e-162 - - - H - - - C-5 cytosine-specific DNA methylase
NNCLEEBI_00345 2.5e-108 - 2.1.1.72, 3.1.21.3 - V ko:K01154,ko:K07317 - ko00000,ko01000,ko02048 DNA modification
NNCLEEBI_00347 7.39e-28 recD2_2 3.1.11.5 - L ko:K01144 - ko00000,ko01000 PIF1-like helicase
NNCLEEBI_00349 6.43e-62 spoVK - - O - - - ATPase family associated with various cellular activities (AAA)
NNCLEEBI_00351 4.73e-110 - - - S - - - overlaps another CDS with the same product name
NNCLEEBI_00352 1.59e-156 yibE - - S - - - overlaps another CDS with the same product name
NNCLEEBI_00353 1.9e-121 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NNCLEEBI_00354 1.75e-58 tnp2 - - L - - - PFAM Transposase, IS204 IS1001 IS1096 IS1165
NNCLEEBI_00355 6.29e-10 tnp2 - - L - - - PFAM Transposase, IS204 IS1001 IS1096 IS1165
NNCLEEBI_00356 7.54e-53 ytkL - - S - - - Belongs to the UPF0173 family
NNCLEEBI_00357 5.71e-229 - - - L - - - Probable transposase
NNCLEEBI_00358 6.96e-13 bCE_4747 - - S - - - Belongs to the UPF0173 family
NNCLEEBI_00359 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
NNCLEEBI_00360 1.85e-97 - - - F - - - Phosphorylase superfamily
NNCLEEBI_00361 1.82e-33 - - - - - - - -
NNCLEEBI_00362 5.54e-139 dkgB - - S - - - reductase
NNCLEEBI_00364 3.2e-27 rimL 1.1.1.25 - J ko:K00014,ko:K03817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko03009 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NNCLEEBI_00365 2.25e-216 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NNCLEEBI_00366 3.21e-256 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NNCLEEBI_00367 1.22e-72 - - - EGP - - - Transmembrane secretion effector
NNCLEEBI_00368 2.11e-174 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
NNCLEEBI_00369 3.44e-66 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
NNCLEEBI_00370 9.68e-235 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NNCLEEBI_00371 5.09e-139 pfoSR - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
NNCLEEBI_00372 3.16e-158 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NNCLEEBI_00373 1e-189 araT 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NNCLEEBI_00374 3.94e-249 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
NNCLEEBI_00375 9.07e-41 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
NNCLEEBI_00376 9.51e-200 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
NNCLEEBI_00377 9.08e-195 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
NNCLEEBI_00378 2.07e-147 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NNCLEEBI_00379 5.91e-61 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
NNCLEEBI_00380 4.56e-177 arcT - - E - - - Cys/Met metabolism PLP-dependent enzyme
NNCLEEBI_00381 1.9e-115 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NNCLEEBI_00382 1.9e-31 veg - - S - - - Biofilm formation stimulator VEG
NNCLEEBI_00383 3.78e-169 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NNCLEEBI_00384 4.87e-112 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NNCLEEBI_00385 7.31e-133 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
NNCLEEBI_00386 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NNCLEEBI_00387 5.58e-163 - - - - - - - -
NNCLEEBI_00388 1.45e-188 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
NNCLEEBI_00389 1.33e-55 - - - ET - - - Bacterial extracellular solute-binding proteins, family 3
NNCLEEBI_00390 5.39e-40 - - - K - - - Bacterial regulatory proteins, tetR family
NNCLEEBI_00391 1.35e-50 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
NNCLEEBI_00392 8.03e-121 - - - L - - - Probable transposase
NNCLEEBI_00393 5.05e-80 - - - L - - - Resolvase, N-terminal domain
NNCLEEBI_00394 3.68e-200 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
NNCLEEBI_00395 1.06e-76 - - - L ko:K07491 - ko00000 Transposase IS200 like
NNCLEEBI_00397 6.87e-130 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
NNCLEEBI_00398 2.82e-217 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
NNCLEEBI_00399 2.75e-160 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NNCLEEBI_00400 0.0 - - - L - - - DNA helicase
NNCLEEBI_00402 1.77e-155 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
NNCLEEBI_00403 2.31e-94 lemA - - S ko:K03744 - ko00000 LemA family
NNCLEEBI_00404 6.71e-67 ymdB - - L - - - phosphatase homologous to the C-terminal domain of histone macroH2A1
NNCLEEBI_00405 5.29e-59 yyaT - - K ko:K02348 - ko00000 protein acetylation
NNCLEEBI_00406 1.29e-11 - - - - - - - -
NNCLEEBI_00407 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
NNCLEEBI_00408 2.66e-279 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
NNCLEEBI_00409 6.28e-44 - - - K - - - Bacterial regulatory proteins, tetR family
NNCLEEBI_00410 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NNCLEEBI_00411 2.57e-276 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NNCLEEBI_00412 2.38e-189 - - - G - - - Transporter, major facilitator family protein
NNCLEEBI_00413 2.06e-113 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
NNCLEEBI_00414 5.29e-191 hpk31 - - T - - - Histidine kinase
NNCLEEBI_00415 1.71e-145 vanR - - K - - - response regulator
NNCLEEBI_00416 1.73e-105 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
NNCLEEBI_00417 4.67e-117 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
NNCLEEBI_00418 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NNCLEEBI_00419 1.39e-106 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NNCLEEBI_00420 2.95e-92 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NNCLEEBI_00421 1.33e-31 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
NNCLEEBI_00422 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NNCLEEBI_00423 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NNCLEEBI_00424 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NNCLEEBI_00425 6.91e-73 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
NNCLEEBI_00427 6.07e-152 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NNCLEEBI_00428 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
NNCLEEBI_00429 9.15e-198 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
NNCLEEBI_00430 5.35e-235 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NNCLEEBI_00431 3.41e-166 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
NNCLEEBI_00443 1.6e-262 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NNCLEEBI_00444 2.64e-308 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
NNCLEEBI_00445 5.56e-87 budA 4.1.1.5 - Q ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
NNCLEEBI_00446 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
NNCLEEBI_00447 2.9e-14 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NNCLEEBI_00448 5.31e-72 lssY 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 phosphatidate phosphatase activity
NNCLEEBI_00449 2.53e-106 lysR5 - - K - - - LysR substrate binding domain
NNCLEEBI_00450 7.78e-154 - - - S ko:K07090 - ko00000 membrane transporter protein
NNCLEEBI_00451 1.98e-42 - - - S - - - Protein of unknown function (DUF1634)
NNCLEEBI_00452 6.86e-159 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
NNCLEEBI_00453 3.13e-286 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
NNCLEEBI_00454 8.89e-21 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NNCLEEBI_00455 2.05e-208 - - - EGP ko:K18934 - ko00000,ko02000 Major Facilitator Superfamily
NNCLEEBI_00456 6.81e-103 - - - S - - - L,D-transpeptidase catalytic domain
NNCLEEBI_00457 7.9e-174 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NNCLEEBI_00458 6.07e-186 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NNCLEEBI_00459 1.07e-34 yuxO - - Q - - - Thioesterase superfamily
NNCLEEBI_00460 1.18e-69 - - - F - - - glutamine amidotransferase
NNCLEEBI_00461 4.13e-189 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
NNCLEEBI_00462 3.51e-146 degV - - S - - - EDD domain protein, DegV family
NNCLEEBI_00463 3.6e-293 cadA - - P - - - P-type ATPase
NNCLEEBI_00464 0.0 - - - E - - - Amino acid permease
NNCLEEBI_00465 4.47e-108 - - - S - - - Membrane
NNCLEEBI_00466 1.66e-57 cps3F - - - - - - -
NNCLEEBI_00467 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
NNCLEEBI_00468 4.7e-192 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NNCLEEBI_00469 5.64e-111 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
NNCLEEBI_00470 3.25e-280 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
NNCLEEBI_00471 3.81e-37 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
NNCLEEBI_00472 2.52e-17 - - - - - - - -
NNCLEEBI_00473 3.47e-79 - - - E - - - GDSL-like Lipase/Acylhydrolase family
NNCLEEBI_00474 3.45e-70 - - - S - - - Protein of unknown function (DUF975)
NNCLEEBI_00475 2.72e-186 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
NNCLEEBI_00476 3.07e-291 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
NNCLEEBI_00477 5.48e-230 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NNCLEEBI_00478 3.04e-212 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
NNCLEEBI_00479 1.49e-223 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
NNCLEEBI_00482 8e-68 - - - S - - - Protein of unknown function (DUF4256)
NNCLEEBI_00483 3.63e-163 metQ - - M ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
NNCLEEBI_00484 1.02e-73 metI - - U ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NNCLEEBI_00485 8.85e-192 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NNCLEEBI_00487 8.73e-49 speA 4.1.1.17, 4.1.1.18, 4.1.1.19 - E ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Orn/Lys/Arg decarboxylase, C-terminal domain
NNCLEEBI_00488 2.17e-73 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 PFAM restriction modification system DNA specificity domain
NNCLEEBI_00489 1.95e-175 - - - L - - - Belongs to the 'phage' integrase family
NNCLEEBI_00490 1.14e-28 - - - S ko:K19092 - ko00000,ko02048 addiction module toxin, RelE StbE family
NNCLEEBI_00491 3.84e-34 - - - L ko:K07473 - ko00000,ko02048 Addiction module antitoxin, RelB DinJ family
NNCLEEBI_00492 5.89e-80 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
NNCLEEBI_00493 1.67e-308 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
NNCLEEBI_00494 1.3e-113 - - - V - - - Type I restriction
NNCLEEBI_00495 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
NNCLEEBI_00496 4.06e-55 - - - V - - - type I restriction modification DNA specificity domain
NNCLEEBI_00497 0.0 speA 4.1.1.17, 4.1.1.18, 4.1.1.19 - E ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Orn/Lys/Arg decarboxylase, C-terminal domain
NNCLEEBI_00498 3.01e-214 npr 1.11.1.1 - S ko:K05910 - ko00000,ko01000 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
NNCLEEBI_00499 7.77e-135 - 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 3-hydroxyacyl-CoA dehydrogenase
NNCLEEBI_00500 1.08e-106 adc 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
NNCLEEBI_00501 2e-107 - - - C - - - nitroreductase
NNCLEEBI_00502 5.38e-38 yphH - - S - - - Cupin domain
NNCLEEBI_00503 3.14e-62 - - - C - - - Flavodoxin
NNCLEEBI_00504 3.61e-71 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
NNCLEEBI_00505 1.28e-130 pgm3 - - G - - - phosphoglycerate mutase
NNCLEEBI_00506 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NNCLEEBI_00507 6.13e-286 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NNCLEEBI_00508 3.8e-69 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NNCLEEBI_00509 3.54e-87 yciB - - M - - - ErfK YbiS YcfS YnhG
NNCLEEBI_00510 6.45e-137 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NNCLEEBI_00511 9.74e-147 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NNCLEEBI_00512 9.18e-168 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
NNCLEEBI_00513 1.69e-201 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NNCLEEBI_00514 1.26e-132 potC - - U ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NNCLEEBI_00515 3.85e-153 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NNCLEEBI_00516 1.31e-124 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NNCLEEBI_00517 9.54e-99 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NNCLEEBI_00518 3.27e-130 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NNCLEEBI_00519 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 C-terminal domain of alpha-glycerophosphate oxidase
NNCLEEBI_00520 9.69e-295 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NNCLEEBI_00521 1.67e-126 - - - V - - - regulation of methylation-dependent chromatin silencing
NNCLEEBI_00522 4.63e-160 - 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 C-5 cytosine-specific DNA methylase
NNCLEEBI_00523 8.19e-08 - - - - - - - -
NNCLEEBI_00524 8.46e-23 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
NNCLEEBI_00525 3.03e-08 - - - S - - - Putative adhesin
NNCLEEBI_00526 2.01e-27 - - - S - - - Protein of unknown function (DUF1700)
NNCLEEBI_00527 1.77e-50 XK27_06915 - - K ko:K10947 - ko00000,ko03000 transcriptional regulator PadR family
NNCLEEBI_00528 2.22e-44 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
NNCLEEBI_00529 2.35e-97 ung2 - - L - - - Uracil-DNA glycosylase
NNCLEEBI_00530 2.23e-209 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NNCLEEBI_00531 4.75e-163 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NNCLEEBI_00532 1.21e-88 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
NNCLEEBI_00533 1.13e-67 - - - S - - - Domain of unknown function (DUF956)
NNCLEEBI_00534 8.07e-188 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
NNCLEEBI_00535 1.69e-153 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
NNCLEEBI_00536 1.11e-192 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
NNCLEEBI_00537 2.17e-101 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 sugar-binding domain protein
NNCLEEBI_00538 6.12e-120 baeS - - T - - - Histidine kinase
NNCLEEBI_00539 1.51e-101 yfiK - - K ko:K02479 - ko00000,ko02022 Bacterial regulatory proteins, luxR family
NNCLEEBI_00540 2.57e-149 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
NNCLEEBI_00541 6.04e-90 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
NNCLEEBI_00542 7.43e-51 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NNCLEEBI_00543 9.36e-43 - - - K - - - MerR HTH family regulatory protein
NNCLEEBI_00544 2.84e-246 ycnB - - U - - - Belongs to the major facilitator superfamily
NNCLEEBI_00545 4.48e-44 - - - S - - - Domain of unknown function (DUF4811)
NNCLEEBI_00546 2.35e-76 yceE - - S - - - haloacid dehalogenase-like hydrolase
NNCLEEBI_00547 2.79e-92 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
NNCLEEBI_00548 1.15e-112 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NNCLEEBI_00549 3.07e-303 - - - L - - - Transposase
NNCLEEBI_00550 7.69e-71 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
NNCLEEBI_00551 1.08e-111 - - - S - - - Predicted membrane protein (DUF2207)
NNCLEEBI_00552 5.45e-26 - - - - - - - -
NNCLEEBI_00553 2.56e-21 - - - M - - - Glycosyl transferase family 2
NNCLEEBI_00554 1.13e-67 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
NNCLEEBI_00555 1.53e-74 - - - P ko:K03499 - ko00000,ko02000 TrkA-N domain
NNCLEEBI_00556 8.44e-145 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
NNCLEEBI_00557 1.08e-118 tnp2 - - L - - - Transposase
NNCLEEBI_00558 1.95e-229 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
NNCLEEBI_00559 6e-62 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NNCLEEBI_00560 7.58e-283 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NNCLEEBI_00561 9.04e-270 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
NNCLEEBI_00562 1.88e-185 scrR - - K ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
NNCLEEBI_00563 3.5e-214 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
NNCLEEBI_00564 1.09e-271 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NNCLEEBI_00566 7.37e-78 - - - T - - - Universal stress protein family
NNCLEEBI_00567 0.0 clpL - - O ko:K04086 - ko00000,ko03110 C-terminal, D2-small domain, of ClpB protein
NNCLEEBI_00568 3.77e-35 - - - - - - - -
NNCLEEBI_00569 6.21e-251 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
NNCLEEBI_00570 4.31e-141 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
NNCLEEBI_00571 7.22e-107 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NNCLEEBI_00572 4.15e-88 - - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
NNCLEEBI_00573 8.02e-35 - - - - - - - -
NNCLEEBI_00574 3.82e-188 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
NNCLEEBI_00575 1.4e-187 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
NNCLEEBI_00576 1.02e-52 arbY - - M - - - family 8
NNCLEEBI_00577 1.04e-36 - - - M - - - Glycosyltransferase like family 2
NNCLEEBI_00578 2.25e-85 nss - - M - - - transferase activity, transferring glycosyl groups
NNCLEEBI_00579 1.12e-38 - - - M - - - Glycosyl transferase, family 8
NNCLEEBI_00580 8.7e-41 - - - M - - - family 8
NNCLEEBI_00581 3.82e-62 - - - M - - - transferase activity, transferring glycosyl groups
NNCLEEBI_00582 1.91e-68 - - - M - - - transferase activity, transferring glycosyl groups
NNCLEEBI_00584 6.18e-44 arbY - - M - - - family 8
NNCLEEBI_00585 4.72e-84 - - - M - - - transferase activity, transferring glycosyl groups
NNCLEEBI_00586 6.87e-67 - - - M - - - transferase activity, transferring glycosyl groups
NNCLEEBI_00587 5e-136 gtf2 - - M - - - A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
NNCLEEBI_00588 4.28e-38 - - - M - - - Glycosyltransferase like family 2
NNCLEEBI_00589 1e-43 - - - M - - - family 8
NNCLEEBI_00590 1.03e-48 - - - S - - - Glycosyltransferase like family 2
NNCLEEBI_00591 1.39e-42 - - - M - - - Glycosyl transferase, family 8
NNCLEEBI_00592 5.72e-41 - - - M - - - Glycosyltransferase like family 2
NNCLEEBI_00593 6.05e-189 gtf1 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NNCLEEBI_00595 1.92e-07 - - - S - - - peptidoglycan binding
NNCLEEBI_00597 2.45e-302 secA2 - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NNCLEEBI_00598 1.39e-18 asp3 - - S ko:K12270 - ko00000,ko02044 Accessory Sec system protein Asp3
NNCLEEBI_00599 3.48e-123 asp2 - - S ko:K12269 - ko00000,ko02044 Accessory Sec system protein Asp2
NNCLEEBI_00600 1.27e-99 asp1 - - S ko:K12268 - ko00000,ko02044 Accessory Sec system protein Asp1
NNCLEEBI_00601 9.86e-64 secY2 - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the accessory SecA2 SecY2 system specifically required for export of
NNCLEEBI_00602 2.63e-103 - - - E - - - IrrE N-terminal-like domain
NNCLEEBI_00603 6.89e-175 - - - S - - - interspecies interaction between organisms
NNCLEEBI_00604 1.6e-261 glpT - - G ko:K02445 - ko00000,ko02000 glycerol-3-phosphate transporter
NNCLEEBI_00605 9.02e-58 - - - S - - - PD-(D/E)XK nuclease family transposase
NNCLEEBI_00606 8.94e-111 - - - GM - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NNCLEEBI_00607 5.2e-34 - - - K - - - MarR family transcriptional regulator
NNCLEEBI_00608 2.57e-70 - - - GM - - - NAD(P)H-binding
NNCLEEBI_00609 7.88e-94 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NNCLEEBI_00610 8.15e-188 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
NNCLEEBI_00611 1.7e-146 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
NNCLEEBI_00612 1.37e-40 - - - S - - - YjbR
NNCLEEBI_00613 3.35e-100 yycI - - S - - - YycH protein
NNCLEEBI_00614 1.07e-125 yycH - - S - - - YycH protein
NNCLEEBI_00615 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NNCLEEBI_00616 2.43e-151 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
NNCLEEBI_00617 8.39e-199 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 FMN-dependent dehydrogenase
NNCLEEBI_00618 7.58e-215 - - - EGP - - - Mycoplasma MFS transporter
NNCLEEBI_00619 1.29e-55 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
NNCLEEBI_00620 2.47e-136 yxeH - - S - - - hydrolase
NNCLEEBI_00621 2.89e-301 XK27_09605 - - V ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter transmembrane region
NNCLEEBI_00622 8.78e-269 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NNCLEEBI_00623 2.33e-41 - - - K - - - Transcriptional regulator, MarR family
NNCLEEBI_00624 1.95e-219 - - - S - - - Putative peptidoglycan binding domain
NNCLEEBI_00625 7.18e-81 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
NNCLEEBI_00626 3.99e-176 - 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 Iron-containing alcohol dehydrogenase
NNCLEEBI_00628 4.93e-225 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
NNCLEEBI_00629 4.1e-137 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
NNCLEEBI_00630 1.12e-278 pepF - - E - - - Oligopeptidase F
NNCLEEBI_00631 1.42e-122 yicL - - EG - - - EamA-like transporter family
NNCLEEBI_00632 1.26e-89 - - - J - - - Acetyltransferase (GNAT) domain
NNCLEEBI_00633 6.51e-213 - - - S - - - Putative threonine/serine exporter
NNCLEEBI_00634 4.44e-141 - - - U ko:K05340 - ko00000,ko02000 sugar transport
NNCLEEBI_00635 8.43e-12 yobS - - K - - - Bacterial regulatory proteins, tetR family
NNCLEEBI_00636 3.68e-192 - - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
NNCLEEBI_00637 5.22e-125 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
NNCLEEBI_00638 6.47e-285 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
NNCLEEBI_00639 3.57e-290 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NNCLEEBI_00640 5.01e-22 yneR - - - - - - -
NNCLEEBI_00641 8.89e-307 pox1 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
NNCLEEBI_00642 5.27e-53 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NNCLEEBI_00643 3.83e-16 - - - S - - - integral membrane protein
NNCLEEBI_00644 1.46e-37 - - - S - - - Protein of unknown function (DUF1211)
NNCLEEBI_00645 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
NNCLEEBI_00646 9.72e-83 - - - D - - - peptidase
NNCLEEBI_00647 1.33e-147 - - - S - - - Glycosyl transferase family 2
NNCLEEBI_00648 1.49e-199 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
NNCLEEBI_00649 1.06e-76 - - - L ko:K07491 - ko00000 Transposase IS200 like
NNCLEEBI_00650 4.98e-139 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 Dehydrogenase
NNCLEEBI_00651 3.82e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NNCLEEBI_00652 7.54e-88 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NNCLEEBI_00653 7.37e-60 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
NNCLEEBI_00654 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NNCLEEBI_00655 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NNCLEEBI_00656 8.39e-194 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NNCLEEBI_00657 4.51e-27 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
NNCLEEBI_00658 1.27e-201 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NNCLEEBI_00659 1.1e-257 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NNCLEEBI_00660 2.29e-20 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
NNCLEEBI_00661 8.2e-65 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NNCLEEBI_00662 3.1e-137 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NNCLEEBI_00663 7.19e-254 nupG - - F ko:K16323 - ko00000,ko02000 Nucleoside
NNCLEEBI_00664 1.17e-152 - - - S - - - Conserved hypothetical protein 698
NNCLEEBI_00665 2.5e-67 - - - K - - - LysR substrate binding domain
NNCLEEBI_00668 1.7e-84 icaB - - G - - - Polysaccharide deacetylase
NNCLEEBI_00669 3.46e-39 - - - S - - - Belongs to the HesB IscA family
NNCLEEBI_00685 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
NNCLEEBI_00686 9.07e-86 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
NNCLEEBI_00687 1.24e-260 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
NNCLEEBI_00688 3.42e-82 - - - C - - - FMN binding
NNCLEEBI_00689 2.03e-291 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NNCLEEBI_00691 3.5e-199 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NNCLEEBI_00692 2e-77 ykhA 3.1.2.20 - I ko:K01073 - ko00000,ko01000 Thioesterase superfamily
NNCLEEBI_00693 5.3e-12 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
NNCLEEBI_00694 7.73e-105 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
NNCLEEBI_00695 7.58e-75 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
NNCLEEBI_00696 2.45e-315 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 Major Facilitator Superfamily
NNCLEEBI_00697 1.44e-129 XK26_06135 - - D - - - Plasmid recombination enzyme
NNCLEEBI_00698 1.06e-76 - - - L ko:K07491 - ko00000 Transposase IS200 like
NNCLEEBI_00699 1.29e-200 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
NNCLEEBI_00700 1.58e-167 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Cobalamin-independent synthase, Catalytic domain
NNCLEEBI_00701 8.35e-71 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
NNCLEEBI_00702 1.46e-249 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
NNCLEEBI_00703 8.95e-204 adhB 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
NNCLEEBI_00704 3.36e-48 - - - C - - - FMN_bind
NNCLEEBI_00705 1.78e-149 pepL 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
NNCLEEBI_00706 9.81e-254 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
NNCLEEBI_00707 1.19e-177 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
NNCLEEBI_00708 3.87e-101 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
NNCLEEBI_00709 8.18e-172 glpQ4 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
NNCLEEBI_00710 5.03e-190 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
NNCLEEBI_00711 5.2e-57 - - - S - - - Cupredoxin-like domain
NNCLEEBI_00712 1.02e-26 - - - S - - - Cupredoxin-like domain
NNCLEEBI_00713 0.0 copA 3.6.3.3, 3.6.3.5, 3.6.3.54 - P ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
NNCLEEBI_00714 1.48e-76 pgm3 - - G - - - phosphoglycerate mutase family
NNCLEEBI_00715 4.38e-72 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
NNCLEEBI_00716 6.95e-112 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NNCLEEBI_00717 7.19e-276 yifK - - E ko:K03293 - ko00000 Amino acid permease
NNCLEEBI_00719 3.12e-60 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
NNCLEEBI_00720 1.57e-145 - - - L ko:K07484 - ko00000 Transposase IS66 family
NNCLEEBI_00721 2.17e-254 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
NNCLEEBI_00722 3.98e-189 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NNCLEEBI_00723 7.43e-217 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NNCLEEBI_00724 8.6e-230 oppD - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NNCLEEBI_00725 1.2e-197 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NNCLEEBI_00726 3.69e-21 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
NNCLEEBI_00727 1.58e-263 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
NNCLEEBI_00728 1.39e-146 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
NNCLEEBI_00729 3.33e-51 - - - K - - - LytTr DNA-binding domain
NNCLEEBI_00731 6.4e-192 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
NNCLEEBI_00732 3.39e-30 - - - K - - - Transcriptional regulator C-terminal region
NNCLEEBI_00733 2.53e-60 - - - S - - - Short repeat of unknown function (DUF308)
NNCLEEBI_00734 9.2e-68 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NNCLEEBI_00735 4.26e-208 oxlT - - P ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
NNCLEEBI_00736 9.62e-86 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter
NNCLEEBI_00737 2.53e-130 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
NNCLEEBI_00738 1.59e-26 - - - K - - - HxlR-like helix-turn-helix
NNCLEEBI_00739 1.42e-31 ytbE - - S - - - reductase
NNCLEEBI_00740 4.88e-43 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NNCLEEBI_00741 2.59e-32 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NNCLEEBI_00743 1.5e-08 vpr 3.4.21.96 - DO ko:K01361,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 PA domain
NNCLEEBI_00744 4.87e-26 - - - K - - - Bacterial regulatory proteins, tetR family
NNCLEEBI_00747 3.01e-51 - - - K - - - Acetyltransferase GNAT Family
NNCLEEBI_00748 2.76e-61 hmpT - - S - - - ECF-type riboflavin transporter, S component
NNCLEEBI_00749 7.19e-87 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
NNCLEEBI_00750 9.02e-07 sdpI - - S - - - Protein of unknown function (DUF1648)
NNCLEEBI_00751 5.53e-140 dat 2.6.1.21 - EH ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 PFAM aminotransferase, class IV
NNCLEEBI_00752 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
NNCLEEBI_00753 2.5e-59 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
NNCLEEBI_00754 2.61e-67 - - - K - - - Transcriptional regulator C-terminal region
NNCLEEBI_00755 1.8e-69 jag - - S ko:K06346 - ko00000 R3H domain protein
NNCLEEBI_00756 2.21e-73 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NNCLEEBI_00757 1.46e-42 - - - S - - - Branched-chain amino acid transport protein (AzlD)
NNCLEEBI_00758 1.71e-97 azlC - - E - - - branched-chain amino acid
NNCLEEBI_00759 1.32e-74 - - - F - - - Nucleoside 2-deoxyribosyltransferase
NNCLEEBI_00760 3.49e-149 dgk1 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
NNCLEEBI_00761 0.0 l1n 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
NNCLEEBI_00762 1.89e-45 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
NNCLEEBI_00763 2.87e-238 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
NNCLEEBI_00764 3.63e-96 XK27_02070 - - S ko:K07078 - ko00000 Nitroreductase family
NNCLEEBI_00765 1.63e-141 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
NNCLEEBI_00767 1.67e-263 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
NNCLEEBI_00768 2.02e-78 XK27_02085 - - K - - - Bacterial regulatory proteins, tetR family
NNCLEEBI_00769 2.42e-143 dhaK2 2.7.1.28, 2.7.1.29, 4.6.1.15 - G ko:K00863 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 ko00000,ko00001,ko00002,ko01000 Dak1 domain
NNCLEEBI_00770 1.25e-191 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
NNCLEEBI_00771 9.87e-89 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
NNCLEEBI_00772 1.7e-66 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 PTS system fructose IIA component
NNCLEEBI_00773 3.08e-135 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NNCLEEBI_00774 7.61e-218 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
NNCLEEBI_00775 6.68e-259 mtlR - - K ko:K03483 - ko00000,ko03000 Mga helix-turn-helix domain
NNCLEEBI_00776 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NNCLEEBI_00777 1.08e-118 tnp2 - - L - - - Transposase
NNCLEEBI_00778 7.14e-237 noxE - - S - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
NNCLEEBI_00779 6.76e-23 - - - V - - - the current gene model (or a revised gene model) may contain a frame shift
NNCLEEBI_00781 3.9e-134 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NNCLEEBI_00782 2.48e-129 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NNCLEEBI_00783 5.54e-121 fliY - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
NNCLEEBI_00784 3.75e-49 - - - K - - - Transcriptional regulator
NNCLEEBI_00785 6.4e-138 - - - P - - - Integral membrane protein TerC family
NNCLEEBI_00786 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NNCLEEBI_00787 1.63e-85 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NNCLEEBI_00788 1.47e-236 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
NNCLEEBI_00789 5.09e-56 - - - K - - - Transcriptional regulator, GntR family
NNCLEEBI_00790 1.09e-121 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NNCLEEBI_00792 4.21e-53 ybjQ - - S - - - Belongs to the UPF0145 family
NNCLEEBI_00793 1.15e-198 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
NNCLEEBI_00794 2.23e-123 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NNCLEEBI_00795 2.46e-198 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NNCLEEBI_00796 3.93e-180 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NNCLEEBI_00797 2.13e-46 - - - - - - - -
NNCLEEBI_00798 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
NNCLEEBI_00799 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
NNCLEEBI_00800 2.93e-82 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
NNCLEEBI_00802 1.73e-93 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
NNCLEEBI_00803 1.94e-78 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Possible lysine decarboxylase
NNCLEEBI_00804 0.0 atp2C1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
NNCLEEBI_00805 1.08e-91 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
NNCLEEBI_00806 3.88e-160 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
NNCLEEBI_00807 2.55e-130 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
NNCLEEBI_00808 2.49e-103 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
NNCLEEBI_00809 4.97e-153 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
NNCLEEBI_00810 1.19e-137 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
NNCLEEBI_00811 2.56e-32 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
NNCLEEBI_00812 2.94e-242 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NNCLEEBI_00813 2.21e-73 - - - S - - - Protein of unknown function (DUF1129)
NNCLEEBI_00814 2.05e-114 - - - S - - - Bacterial membrane protein, YfhO
NNCLEEBI_00815 1.81e-85 - - - I - - - Alpha/beta hydrolase family
NNCLEEBI_00816 2.61e-21 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
NNCLEEBI_00817 1.95e-46 - - - - - - - -
NNCLEEBI_00818 6.49e-70 - - - V - - - Abi-like protein
NNCLEEBI_00819 5.14e-132 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
NNCLEEBI_00820 1.6e-126 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NNCLEEBI_00821 3.47e-138 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
NNCLEEBI_00822 1.98e-71 - - - S - - - ECF transporter, substrate-specific component
NNCLEEBI_00823 1.16e-128 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
NNCLEEBI_00824 7.78e-112 - - - S - - - NADPH-dependent FMN reductase
NNCLEEBI_00825 6.51e-36 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
NNCLEEBI_00826 6.65e-89 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
NNCLEEBI_00828 4.49e-192 - - - EGP - - - Major Facilitator
NNCLEEBI_00829 3.13e-83 - - - S - - - Haloacid dehalogenase-like hydrolase
NNCLEEBI_00830 3.72e-114 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
NNCLEEBI_00831 3.69e-47 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
NNCLEEBI_00832 4.04e-148 cps3J - - M - - - Domain of unknown function (DUF4422)
NNCLEEBI_00833 1.43e-76 - - - S - - - Glycosyltransferase like family 2
NNCLEEBI_00834 4.67e-78 - - - S - - - Glycosyltransferase like family 2
NNCLEEBI_00835 8.43e-183 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NNCLEEBI_00836 2.35e-132 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NNCLEEBI_00837 3.12e-214 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NNCLEEBI_00838 1.28e-160 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NNCLEEBI_00839 1.09e-143 nagZ 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Glycosyl hydrolase family 3 N terminal domain
NNCLEEBI_00840 3.32e-106 - - - S - - - Glycosyl transferase family 2
NNCLEEBI_00841 2.84e-179 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NNCLEEBI_00842 9.12e-87 - - - M - - - Glycosyl transferase family 2
NNCLEEBI_00843 4.84e-51 - - - M - - - Glycosyltransferase family 92
NNCLEEBI_00844 5.61e-123 - - - S - - - Glycosyltransferase WbsX
NNCLEEBI_00845 1.7e-23 - - - S - - - Bacterial transferase hexapeptide (six repeats)
NNCLEEBI_00846 8.29e-31 cotSA - - M ko:K06338 - ko00000 Spore coat protein
NNCLEEBI_00847 6.59e-13 - - - S - - - EpsG family
NNCLEEBI_00848 2.39e-81 - - - M - - - Glycosyl transferase family 2
NNCLEEBI_00849 1.15e-122 - - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
NNCLEEBI_00851 1.4e-270 - 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 UDP binding domain
NNCLEEBI_00852 9.94e-99 epsB - - M - - - biosynthesis protein
NNCLEEBI_00853 4.48e-117 ywqD - - D - - - Capsular exopolysaccharide family
NNCLEEBI_00854 2.97e-142 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
NNCLEEBI_00855 7.73e-161 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
NNCLEEBI_00856 5.92e-116 epsE2 - - M - - - Bacterial sugar transferase
NNCLEEBI_00857 4.04e-125 - - - M - - - Core-2/I-Branching enzyme
NNCLEEBI_00858 5.53e-247 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
NNCLEEBI_00859 7.92e-63 - - GT2 M ko:K12997 - ko00000,ko01000,ko01003,ko01005 Glycosyl transferase, family 2
NNCLEEBI_00860 1.84e-202 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
NNCLEEBI_00861 1.06e-67 - - - - - - - -
NNCLEEBI_00862 1.76e-94 - - - M - - - transferase activity, transferring glycosyl groups
NNCLEEBI_00863 1.3e-06 - - - V - - - the current gene model (or a revised gene model) may contain a frame shift
NNCLEEBI_00864 2.12e-84 - - - D - - - Peptidase family M23
NNCLEEBI_00866 1.62e-170 tetA - - EGP ko:K08151,ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko01504,ko02000 Major facilitator Superfamily
NNCLEEBI_00867 4.35e-44 - - - S - - - MazG nucleotide pyrophosphohydrolase domain
NNCLEEBI_00868 5.13e-268 potE - - E - - - Amino Acid
NNCLEEBI_00869 2e-240 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
NNCLEEBI_00870 3.91e-143 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NNCLEEBI_00871 4.38e-53 - - - E - - - GDSL-like Lipase/Acylhydrolase
NNCLEEBI_00872 1.84e-169 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
NNCLEEBI_00873 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
NNCLEEBI_00875 7.41e-255 - - - L - - - transposition, DNA-mediated
NNCLEEBI_00876 3.5e-122 - - - J ko:K19545 - ko00000,ko01504 Aminoglycoside-2''-adenylyltransferase
NNCLEEBI_00877 1.36e-32 - - - S - - - Psort location CytoplasmicMembrane, score
NNCLEEBI_00878 5.35e-132 - - - G - - - Peptidase_C39 like family
NNCLEEBI_00879 3.06e-220 - - - S - - - AAA domain
NNCLEEBI_00880 1.08e-118 tnp2 - - L - - - Transposase
NNCLEEBI_00881 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NNCLEEBI_00882 2.79e-206 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NNCLEEBI_00883 5.29e-119 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NNCLEEBI_00884 1.23e-85 azr 1.5.1.36 - S ko:K22394 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
NNCLEEBI_00885 5.89e-196 XK27_09615 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
NNCLEEBI_00886 6.04e-67 - - - T ko:K16923 - ko00000,ko00002,ko02000 phosphorelay sensor kinase activity
NNCLEEBI_00887 4.49e-187 iunH3 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Inosine-uridine preferring nucleoside hydrolase
NNCLEEBI_00888 9.88e-59 cps3I - - G - - - Acyltransferase family
NNCLEEBI_00889 4.55e-20 - - - - - - - -
NNCLEEBI_00890 5.13e-191 XK27_08315 - - M - - - Sulfatase
NNCLEEBI_00892 9.42e-49 - - - - - - - -
NNCLEEBI_00893 7.86e-98 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NNCLEEBI_00894 3.97e-221 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
NNCLEEBI_00895 1.21e-160 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NNCLEEBI_00896 2.54e-214 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
NNCLEEBI_00897 3.27e-113 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NNCLEEBI_00898 4.24e-68 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
NNCLEEBI_00899 8.88e-226 XK27_08315 - - M - - - Sulfatase
NNCLEEBI_00901 1.18e-212 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
NNCLEEBI_00902 1.17e-144 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
NNCLEEBI_00903 2.28e-127 treB - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NNCLEEBI_00904 1.14e-81 pgm1 - - G - - - phosphoglycerate mutase
NNCLEEBI_00905 4.18e-107 pncA - - Q - - - isochorismatase
NNCLEEBI_00906 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
NNCLEEBI_00907 5.28e-131 gntR - - K - - - UbiC transcription regulator-associated domain protein
NNCLEEBI_00908 6.68e-219 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
NNCLEEBI_00909 1.7e-55 hxlR - - K - - - Transcriptional regulator, HxlR family
NNCLEEBI_00910 3.13e-208 - - - C - - - Luciferase-like monooxygenase
NNCLEEBI_00911 1.81e-85 - 1.5.1.38 - S ko:K00299 ko00740,ko00920,ko01100,map00740,map00920,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
NNCLEEBI_00912 1.61e-146 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
NNCLEEBI_00913 7.5e-97 nt5e 3.1.3.18 - L ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 haloacid dehalogenase-like hydrolase
NNCLEEBI_00914 1.18e-75 - - - EG - - - EamA-like transporter family
NNCLEEBI_00915 6.45e-148 ydbI - - K - - - AI-2E family transporter
NNCLEEBI_00916 1.1e-217 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
NNCLEEBI_00917 3.53e-158 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NNCLEEBI_00918 1.15e-73 - - - K - - - WYL domain
NNCLEEBI_00919 1.72e-09 - - - S - - - Mor transcription activator family
NNCLEEBI_00925 1.93e-158 yhgE - - V ko:K01421 - ko00000 domain protein
NNCLEEBI_00926 2.08e-162 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
NNCLEEBI_00927 1.81e-24 - - - - - - - -
NNCLEEBI_00928 3.08e-133 - - - E - - - AzlC protein
NNCLEEBI_00929 2.61e-52 - - - S - - - branched-chain amino acid
NNCLEEBI_00930 3.01e-82 - - - I - - - alpha/beta hydrolase fold
NNCLEEBI_00931 1.44e-23 - - - - - - - -
NNCLEEBI_00932 9.17e-75 - 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 phosphatase
NNCLEEBI_00933 8.5e-29 - - - - - - - -
NNCLEEBI_00934 1.44e-117 yjbO 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
NNCLEEBI_00935 1.77e-115 mntR - - K ko:K03709 - ko00000,ko03000 Helix-turn-helix diphteria tox regulatory element
NNCLEEBI_00936 1.37e-37 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
NNCLEEBI_00937 9.59e-104 - - - S - - - Putative threonine/serine exporter
NNCLEEBI_00938 1.97e-64 - - - S - - - Threonine/Serine exporter, ThrE
NNCLEEBI_00939 3.41e-156 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
NNCLEEBI_00940 2.57e-111 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
NNCLEEBI_00941 3.2e-45 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
NNCLEEBI_00942 1.59e-28 crcB1 - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NNCLEEBI_00943 1.18e-28 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NNCLEEBI_00944 6.6e-84 - - - S - - - Uncharacterised protein, DegV family COG1307
NNCLEEBI_00946 1.09e-68 ccl - - S - - - QueT transporter
NNCLEEBI_00947 7.29e-46 XK27_01315 - - S - - - Protein of unknown function (DUF2829)
NNCLEEBI_00948 1.57e-131 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
NNCLEEBI_00949 5.62e-218 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
NNCLEEBI_00950 1.51e-121 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NNCLEEBI_00951 9.6e-112 - - - S - - - Alpha beta hydrolase
NNCLEEBI_00952 8.45e-58 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NNCLEEBI_00953 1.97e-174 - - - V - - - MatE
NNCLEEBI_00954 6.88e-200 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
NNCLEEBI_00955 1.6e-91 hlyD3 - - M ko:K02005 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NNCLEEBI_00956 2.78e-126 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
NNCLEEBI_00957 1.13e-162 - - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
NNCLEEBI_00958 4.21e-95 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
NNCLEEBI_00959 3.91e-33 - - - - - - - -
NNCLEEBI_00960 6.84e-232 yhdP - - S - - - Transporter associated domain
NNCLEEBI_00961 8.78e-102 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
NNCLEEBI_00962 0.0 - - - L - - - Helicase C-terminal domain protein
NNCLEEBI_00963 5.89e-316 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NNCLEEBI_00964 1.76e-268 yhdG - - E ko:K03294 - ko00000 Amino Acid
NNCLEEBI_00965 1e-68 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
NNCLEEBI_00966 1.03e-16 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
NNCLEEBI_00967 5.93e-130 - - - - - - - -
NNCLEEBI_00968 1.29e-18 - - - - - - - -
NNCLEEBI_00969 2.45e-132 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NNCLEEBI_00970 9.76e-126 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NNCLEEBI_00971 4.89e-111 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NNCLEEBI_00972 5.39e-104 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NNCLEEBI_00973 5.79e-240 steT - - E ko:K03294 - ko00000 amino acid
NNCLEEBI_00974 1.4e-14 - - - K - - - Acetyltransferase (GNAT) domain
NNCLEEBI_00975 9.69e-187 XK27_10475 - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
NNCLEEBI_00976 9.33e-68 rpiA1 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
NNCLEEBI_00977 3.74e-101 - - - K - - - rpiR family
NNCLEEBI_00978 4.03e-216 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NNCLEEBI_00979 7.65e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
NNCLEEBI_00980 2.82e-140 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NNCLEEBI_00981 6.55e-130 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
NNCLEEBI_00982 3.85e-52 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NNCLEEBI_00983 4.58e-183 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NNCLEEBI_00984 5.93e-60 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NNCLEEBI_00985 9.15e-72 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NNCLEEBI_00986 2.31e-149 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NNCLEEBI_00987 8.95e-95 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NNCLEEBI_00988 2.63e-32 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
NNCLEEBI_00989 5.05e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NNCLEEBI_00990 2.98e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NNCLEEBI_00991 3.84e-62 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NNCLEEBI_00992 1.61e-119 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NNCLEEBI_00993 4.1e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NNCLEEBI_00994 5.17e-86 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NNCLEEBI_00995 4.99e-113 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NNCLEEBI_00996 2.4e-73 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NNCLEEBI_00997 2.08e-106 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NNCLEEBI_00998 1.65e-31 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
NNCLEEBI_00999 1.13e-88 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
NNCLEEBI_01000 1.05e-266 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NNCLEEBI_01001 8.94e-143 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NNCLEEBI_01002 7.16e-47 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NNCLEEBI_01003 1.72e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
NNCLEEBI_01004 7.34e-74 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NNCLEEBI_01005 1.24e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NNCLEEBI_01006 1.93e-198 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NNCLEEBI_01007 4.47e-71 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
NNCLEEBI_01008 1.13e-127 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NNCLEEBI_01009 1.77e-139 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NNCLEEBI_01010 3.1e-138 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NNCLEEBI_01011 6.22e-160 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NNCLEEBI_01012 1.04e-99 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NNCLEEBI_01013 2.29e-79 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
NNCLEEBI_01014 1.27e-34 - - - - - - - -
NNCLEEBI_01015 4e-307 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
NNCLEEBI_01016 2.13e-190 - - - V - - - RRXRR protein
NNCLEEBI_01017 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
NNCLEEBI_01018 5.24e-49 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
NNCLEEBI_01019 1.05e-07 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
NNCLEEBI_01020 6.34e-111 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NNCLEEBI_01021 5.68e-140 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
NNCLEEBI_01022 1.48e-41 - - - K - - - transcriptional regulator (TetR family)
NNCLEEBI_01023 6.4e-111 aad 3.4.13.22 - E ko:K08641 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
NNCLEEBI_01024 0.0 spxB 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
NNCLEEBI_01025 7.63e-69 - - - M - - - LysM domain protein
NNCLEEBI_01026 6.21e-144 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NNCLEEBI_01027 3.52e-130 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
NNCLEEBI_01028 3.32e-72 - - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
NNCLEEBI_01029 1.43e-68 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
NNCLEEBI_01030 4.09e-261 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NNCLEEBI_01031 4.44e-180 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NNCLEEBI_01032 2.2e-110 - - - S - - - (CBS) domain
NNCLEEBI_01033 8.16e-202 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
NNCLEEBI_01034 1.45e-95 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NNCLEEBI_01035 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NNCLEEBI_01036 9.35e-173 yabM - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
NNCLEEBI_01037 2.22e-42 yabO - - J - - - S4 domain protein
NNCLEEBI_01038 2.83e-26 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
NNCLEEBI_01039 1.23e-62 yabR - - J ko:K07571 - ko00000 RNA binding
NNCLEEBI_01040 2.59e-117 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NNCLEEBI_01041 3.54e-100 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
NNCLEEBI_01042 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NNCLEEBI_01043 1.13e-167 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NNCLEEBI_01044 2.4e-214 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NNCLEEBI_01045 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
NNCLEEBI_01049 2.85e-183 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NNCLEEBI_01050 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
NNCLEEBI_01051 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NNCLEEBI_01052 2.8e-204 camS - - S - - - sex pheromone
NNCLEEBI_01053 1.34e-50 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NNCLEEBI_01054 7.24e-295 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NNCLEEBI_01055 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NNCLEEBI_01056 2.17e-184 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
NNCLEEBI_01057 4.64e-265 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NNCLEEBI_01058 9.29e-68 - - - L - - - Resolvase, N terminal domain
NNCLEEBI_01059 1.99e-60 - - - L - - - COG COG1961 Site-specific recombinases, DNA invertase Pin homologs
NNCLEEBI_01060 0.0 - - - L - - - Psort location Cytoplasmic, score 8.87
NNCLEEBI_01061 1.48e-30 - - - - - - - -
NNCLEEBI_01062 1.93e-42 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
NNCLEEBI_01065 7.64e-70 - - - S - - - UPF0489 domain
NNCLEEBI_01066 5.57e-137 - - - L ko:K07448 - ko00000,ko02048 Mrr N-terminal domain
NNCLEEBI_01069 4.23e-13 - - - S ko:K06889 - ko00000 X-Pro dipeptidyl-peptidase (S15 family)
NNCLEEBI_01070 6.2e-13 - - - K ko:K03826 - ko00000,ko01000 acetyltransferase
NNCLEEBI_01071 1.36e-08 yiaC - - K ko:K03826 - ko00000,ko01000 Acetyltransferase (GNAT) domain
NNCLEEBI_01072 1.06e-39 - - - L ko:K07483,ko:K07497 - ko00000 Helix-turn-helix domain
NNCLEEBI_01073 2.42e-22 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
NNCLEEBI_01074 1.81e-82 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
NNCLEEBI_01076 2.28e-51 - - - - - - - -
NNCLEEBI_01077 3.9e-135 - - - S - - - Domain of unknown function (DUF4343)
NNCLEEBI_01078 3.61e-71 - - - F - - - Cytidine and deoxycytidylate deaminase zinc-binding region
NNCLEEBI_01079 1.09e-93 - - - S - - - Domain of unknown function (DUF3841)
NNCLEEBI_01080 4.9e-288 - - - S - - - Protein of unknown function DUF262
NNCLEEBI_01082 6.54e-235 - - - L - - - Probable transposase
NNCLEEBI_01083 3.94e-195 spoVK - - O ko:K06413 - ko00000 PFAM ATPase family associated with various cellular activities (AAA)
NNCLEEBI_01084 2.61e-90 - - - L ko:K07491 - ko00000 Transposase IS200 like
NNCLEEBI_01085 3.07e-303 - - - L - - - Transposase
NNCLEEBI_01086 8.41e-200 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
NNCLEEBI_01087 4.19e-199 - - - C - - - Oxidoreductase
NNCLEEBI_01088 1.25e-92 ywlG - - S - - - Belongs to the UPF0340 family
NNCLEEBI_01089 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
NNCLEEBI_01090 1.73e-121 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NNCLEEBI_01091 3.47e-75 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NNCLEEBI_01092 4.28e-223 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
NNCLEEBI_01093 2.77e-19 - - - S ko:K09790 - ko00000 Protein of unknown function (DUF454)
NNCLEEBI_01094 1.07e-301 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NNCLEEBI_01095 9.7e-250 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
NNCLEEBI_01096 3.63e-267 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
NNCLEEBI_01097 4.54e-51 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
NNCLEEBI_01098 4.4e-203 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NNCLEEBI_01099 9.01e-77 apl 3.1.3.1 - S ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 SNARE associated Golgi protein
NNCLEEBI_01100 6.86e-129 ypuA - - S - - - Protein of unknown function (DUF1002)
NNCLEEBI_01101 8.85e-299 - - - M - - - Rib/alpha-like repeat
NNCLEEBI_01102 2.15e-59 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
NNCLEEBI_01103 2.3e-78 usp2 - - T - - - Belongs to the universal stress protein A family
NNCLEEBI_01104 2.36e-52 - - - K - - - Bacterial regulatory proteins, tetR family
NNCLEEBI_01105 3.65e-74 napB - - K - - - transcriptional
NNCLEEBI_01106 7.18e-91 mleR - - K - - - LysR family
NNCLEEBI_01107 2.78e-312 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
NNCLEEBI_01108 2.15e-162 mleP2 - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
NNCLEEBI_01109 5.7e-82 - - - S - - - ECF transporter, substrate-specific component
NNCLEEBI_01110 2.58e-77 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
NNCLEEBI_01111 1.37e-96 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NNCLEEBI_01112 3.15e-254 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
NNCLEEBI_01113 5.37e-119 tnp2 - - L - - - Transposase
NNCLEEBI_01114 1.1e-58 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
NNCLEEBI_01115 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
NNCLEEBI_01116 6.48e-123 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
NNCLEEBI_01117 2.08e-147 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NNCLEEBI_01118 2.79e-117 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
NNCLEEBI_01119 7.34e-228 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
NNCLEEBI_01121 1.96e-54 - - - - - - - -
NNCLEEBI_01122 1.32e-41 - - - K - - - GNAT family
NNCLEEBI_01123 5.6e-263 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
NNCLEEBI_01124 2.41e-276 gdhA 1.4.1.3, 1.4.1.4 - E ko:K00261,ko:K00262 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 ko00000,ko00001,ko00002,ko01000,ko04147 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
NNCLEEBI_01125 4.21e-36 - - - O - - - ADP-ribosylglycohydrolase
NNCLEEBI_01126 4.16e-249 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
NNCLEEBI_01127 1.13e-32 - - - S - - - Domain of unknown function (DUF4828)
NNCLEEBI_01128 1.32e-161 mocA - - S - - - Oxidoreductase
NNCLEEBI_01129 3.52e-62 yfmL - - L - - - DEAD DEAH box helicase
NNCLEEBI_01130 4.27e-118 yfmL - - L - - - DEAD DEAH box helicase
NNCLEEBI_01133 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
NNCLEEBI_01134 2.68e-125 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
NNCLEEBI_01135 2.47e-270 - - - G ko:K16211 - ko00000,ko02000 Transporter, major facilitator family protein
NNCLEEBI_01136 1.92e-95 - 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
NNCLEEBI_01137 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
NNCLEEBI_01138 2.59e-109 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
NNCLEEBI_01139 0.0 - - - E - - - Amino acid permease
NNCLEEBI_01140 1.73e-229 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 Thermophilic metalloprotease (M29)
NNCLEEBI_01141 1.86e-215 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NNCLEEBI_01142 2.43e-90 - - - K - - - Sugar-specific transcriptional regulator TrmB
NNCLEEBI_01143 1.31e-154 - - - S - - - Sulfite exporter TauE/SafE
NNCLEEBI_01144 9.8e-152 - 4.3.1.12 - E ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 ko00000,ko00001,ko01000 Ornithine cyclodeaminase/mu-crystallin family
NNCLEEBI_01145 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
NNCLEEBI_01146 1.33e-67 gtcA - - S - - - Teichoic acid glycosylation protein
NNCLEEBI_01147 2.04e-69 ykuP - - C ko:K03839 - ko00000 Flavodoxin
NNCLEEBI_01148 2.49e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
NNCLEEBI_01149 5.63e-195 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
NNCLEEBI_01150 6.29e-16 - 3.5.1.28 CBM50 M ko:K22409 - ko00000,ko01000 Lysin motif
NNCLEEBI_01151 1.14e-119 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
NNCLEEBI_01153 5.37e-119 tnp2 - - L - - - Transposase
NNCLEEBI_01154 4.29e-260 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
NNCLEEBI_01157 4.28e-115 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NNCLEEBI_01158 9.25e-124 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
NNCLEEBI_01159 1.65e-113 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NNCLEEBI_01160 8.88e-307 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NNCLEEBI_01161 7.58e-165 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NNCLEEBI_01162 1.06e-76 - - - L ko:K07491 - ko00000 Transposase IS200 like
NNCLEEBI_01163 2.77e-23 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
NNCLEEBI_01164 1.38e-124 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
NNCLEEBI_01165 5.71e-316 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
NNCLEEBI_01166 2.41e-56 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
NNCLEEBI_01168 1.08e-147 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NNCLEEBI_01169 4.29e-163 - - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
NNCLEEBI_01170 4.1e-109 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NNCLEEBI_01171 1.72e-85 tnp2 - - L - - - PFAM Transposase, IS204 IS1001 IS1096 IS1165
NNCLEEBI_01172 8.32e-23 - - - L - - - Transposase
NNCLEEBI_01173 2.77e-45 - - - S - - - Enterocin A Immunity
NNCLEEBI_01174 7.36e-281 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
NNCLEEBI_01175 8.26e-26 HA62_12640 - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
NNCLEEBI_01176 1.38e-94 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
NNCLEEBI_01177 8e-284 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NNCLEEBI_01178 2.78e-195 yacL - - S - - - domain protein
NNCLEEBI_01179 7.38e-313 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NNCLEEBI_01180 2.15e-261 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
NNCLEEBI_01181 3.45e-73 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NNCLEEBI_01182 2.29e-139 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NNCLEEBI_01183 1.93e-92 yacP - - S ko:K06962 - ko00000 YacP-like NYN domain
NNCLEEBI_01184 3.3e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
NNCLEEBI_01185 3.08e-16 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NNCLEEBI_01186 3.13e-109 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
NNCLEEBI_01187 2.58e-88 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NNCLEEBI_01188 9.98e-150 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NNCLEEBI_01189 1.1e-97 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NNCLEEBI_01190 2.18e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NNCLEEBI_01191 1.27e-71 - - - - - - - -
NNCLEEBI_01192 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NNCLEEBI_01193 1.1e-203 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NNCLEEBI_01194 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NNCLEEBI_01195 1.81e-58 nrdI - - F ko:K03647 - ko00000 NrdI Flavodoxin like
NNCLEEBI_01196 1.36e-37 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
NNCLEEBI_01197 2.25e-96 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
NNCLEEBI_01198 1.11e-80 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NNCLEEBI_01199 3.13e-267 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NNCLEEBI_01200 3.64e-52 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NNCLEEBI_01201 6.62e-126 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NNCLEEBI_01202 4.16e-39 yaaL - - S - - - Protein of unknown function (DUF2508)
NNCLEEBI_01203 3.09e-83 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NNCLEEBI_01204 4.19e-106 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
NNCLEEBI_01205 3.85e-52 yabA - - L - - - Involved in initiation control of chromosome replication
NNCLEEBI_01206 5.19e-133 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NNCLEEBI_01207 5.71e-103 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
NNCLEEBI_01208 1.99e-178 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 Asparaginase
NNCLEEBI_01209 3.01e-87 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
NNCLEEBI_01210 1.9e-19 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NNCLEEBI_01211 1.45e-205 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NNCLEEBI_01212 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
NNCLEEBI_01213 1.52e-126 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NNCLEEBI_01214 2.28e-40 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
NNCLEEBI_01215 1.7e-46 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NNCLEEBI_01216 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NNCLEEBI_01217 0.0 - - - P ko:K12952 - ko00000,ko01000 COG COG0474 Cation transport ATPase
NNCLEEBI_01218 0.0 ydaO - - E - - - amino acid
NNCLEEBI_01219 2.17e-199 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
NNCLEEBI_01220 1.51e-159 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
NNCLEEBI_01221 1.4e-69 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
NNCLEEBI_01222 7.08e-105 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NNCLEEBI_01223 4.85e-120 yycB - - P ko:K03449 - ko00000,ko02000 Major Facilitator Superfamily
NNCLEEBI_01224 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NNCLEEBI_01225 4.56e-207 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NNCLEEBI_01226 4.95e-81 minJ - - O - - - Domain present in PSD-95, Dlg, and ZO-1/2.
NNCLEEBI_01227 7.27e-111 phoP - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
NNCLEEBI_01228 1.04e-103 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NNCLEEBI_01229 1.02e-10 - - - K ko:K03973 - ko00000,ko02048,ko03000 PspC domain
NNCLEEBI_01230 2.17e-35 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
NNCLEEBI_01231 5.85e-168 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NNCLEEBI_01232 4.11e-143 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NNCLEEBI_01233 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
NNCLEEBI_01234 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NNCLEEBI_01235 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NNCLEEBI_01236 1.23e-107 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NNCLEEBI_01237 2.28e-101 - - - GM - - - NAD dependent epimerase dehydratase family protein
NNCLEEBI_01238 1.01e-160 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
NNCLEEBI_01239 9.11e-195 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
NNCLEEBI_01240 2.05e-191 whiA - - K ko:K09762 - ko00000 May be required for sporulation
NNCLEEBI_01241 2.07e-128 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NNCLEEBI_01243 6.46e-174 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
NNCLEEBI_01244 1.19e-231 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NNCLEEBI_01245 1.99e-264 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
NNCLEEBI_01246 9.95e-165 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NNCLEEBI_01247 4.33e-298 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NNCLEEBI_01248 1.08e-118 tnp2 - - L - - - Transposase
NNCLEEBI_01249 4.97e-168 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NNCLEEBI_01250 7.94e-134 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
NNCLEEBI_01251 1.62e-211 yclK - - T - - - Histidine kinase
NNCLEEBI_01252 3.27e-190 - - - E - - - Major Facilitator Superfamily
NNCLEEBI_01253 4.45e-224 eriC - - P ko:K03281 - ko00000 chloride
NNCLEEBI_01254 1.19e-32 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
NNCLEEBI_01255 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NNCLEEBI_01256 4.3e-91 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NNCLEEBI_01257 1.37e-53 - - - - - - - -
NNCLEEBI_01258 1.18e-148 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
NNCLEEBI_01259 1.52e-134 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NNCLEEBI_01260 7.01e-181 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
NNCLEEBI_01261 7.04e-73 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
NNCLEEBI_01262 3.34e-90 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
NNCLEEBI_01263 4.26e-146 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
NNCLEEBI_01264 3.92e-92 - - - S - - - Protein of unknown function (DUF1361)
NNCLEEBI_01265 4.8e-163 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NNCLEEBI_01266 1.13e-87 ybbR - - S - - - YbbR-like protein
NNCLEEBI_01267 5.91e-284 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NNCLEEBI_01268 3.2e-38 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
NNCLEEBI_01269 5.34e-164 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
NNCLEEBI_01270 6.04e-24 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
NNCLEEBI_01271 8.54e-251 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NNCLEEBI_01272 9.29e-207 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NNCLEEBI_01273 1.44e-83 - - - J ko:K03976 - ko00000,ko01000,ko03016 Aminoacyl-tRNA editing domain
NNCLEEBI_01274 1.06e-126 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
NNCLEEBI_01275 2.62e-111 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NNCLEEBI_01276 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
NNCLEEBI_01277 1.48e-136 ymfF - - S - - - Peptidase M16 inactive domain protein
NNCLEEBI_01278 1.6e-185 ymfH - - S - - - Peptidase M16
NNCLEEBI_01279 1.49e-115 ymfI 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
NNCLEEBI_01280 7.25e-85 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
NNCLEEBI_01281 3.46e-110 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NNCLEEBI_01282 1.84e-203 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NNCLEEBI_01283 4.38e-256 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
NNCLEEBI_01284 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NNCLEEBI_01285 4.93e-288 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NNCLEEBI_01286 2.19e-91 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NNCLEEBI_01287 7.18e-194 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NNCLEEBI_01288 1.66e-230 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NNCLEEBI_01289 1.46e-263 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NNCLEEBI_01290 3.02e-20 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 protein transport
NNCLEEBI_01292 1.04e-78 uspA3 - - T - - - universal stress protein
NNCLEEBI_01294 4.82e-263 - - - E ko:K03294 - ko00000 Amino Acid
NNCLEEBI_01295 3.54e-150 lutA - - C ko:K18928 - ko00000 Cysteine-rich domain
NNCLEEBI_01296 4.06e-310 lutB - - C ko:K18929 - ko00000 4Fe-4S dicluster domain
NNCLEEBI_01297 4.44e-85 lutC - - S ko:K00782 - ko00000 LUD domain
NNCLEEBI_01298 6.8e-185 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NNCLEEBI_01299 3.5e-18 - - - - - - - -
NNCLEEBI_01300 1.53e-154 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
NNCLEEBI_01301 3.69e-237 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NNCLEEBI_01302 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NNCLEEBI_01303 4.06e-48 yrzL - - S - - - Belongs to the UPF0297 family
NNCLEEBI_01304 6.38e-78 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NNCLEEBI_01305 4.23e-44 yrzB - - S - - - Belongs to the UPF0473 family
NNCLEEBI_01306 3e-16 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NNCLEEBI_01307 5.44e-20 cvpA - - S - - - Colicin V production protein
NNCLEEBI_01308 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NNCLEEBI_01309 2.59e-54 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
NNCLEEBI_01310 6.8e-103 - - - I - - - Pfam Lipase (class 3)
NNCLEEBI_01311 1.02e-11 - - - V - - - site-specific DNA-methyltransferase (adenine-specific) activity
NNCLEEBI_01312 3.55e-79 yslB - - S - - - Protein of unknown function (DUF2507)
NNCLEEBI_01313 1.79e-93 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NNCLEEBI_01314 1.04e-52 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
NNCLEEBI_01317 8.13e-177 - 1.1.1.29 - C ko:K00018 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NNCLEEBI_01318 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NNCLEEBI_01319 5.76e-273 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NNCLEEBI_01320 2.54e-255 oatA - - I - - - Acyltransferase
NNCLEEBI_01321 1.97e-137 - - - L ko:K07484 - ko00000 Transposase IS66 family
NNCLEEBI_01323 3.12e-60 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
NNCLEEBI_01325 1.68e-22 - - - - - - - -
NNCLEEBI_01327 2.14e-179 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NNCLEEBI_01328 1.95e-127 yqjQ - - S ko:K07124 - ko00000 Enoyl-(Acyl carrier protein) reductase
NNCLEEBI_01329 1.02e-267 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
NNCLEEBI_01330 3.03e-104 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NNCLEEBI_01331 0.0 - - - S - - - membrane
NNCLEEBI_01332 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
NNCLEEBI_01333 2.11e-36 - - - S - - - Protein of unknown function (DUF3290)
NNCLEEBI_01334 3.06e-96 yviA - - S - - - Protein of unknown function (DUF421)
NNCLEEBI_01336 6.88e-157 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
NNCLEEBI_01337 5.17e-253 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
NNCLEEBI_01338 3.44e-69 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
NNCLEEBI_01339 6.35e-97 uspA - - T - - - universal stress protein
NNCLEEBI_01341 5.46e-246 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
NNCLEEBI_01342 1.03e-31 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
NNCLEEBI_01343 5.9e-130 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NNCLEEBI_01344 6.33e-73 yebR 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
NNCLEEBI_01345 2.64e-222 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NNCLEEBI_01346 4.14e-204 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
NNCLEEBI_01347 1.44e-248 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NNCLEEBI_01348 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NNCLEEBI_01349 2.43e-169 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
NNCLEEBI_01350 2.27e-102 radC - - L ko:K03630 - ko00000 DNA repair protein
NNCLEEBI_01351 1.96e-29 - - - K ko:K03704 - ko00000,ko03000 Cold shock
NNCLEEBI_01352 3.89e-206 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
NNCLEEBI_01353 1.64e-121 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
NNCLEEBI_01354 2.3e-71 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
NNCLEEBI_01355 4.14e-97 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
NNCLEEBI_01356 4.59e-162 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
NNCLEEBI_01357 1.23e-121 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
NNCLEEBI_01358 1.41e-115 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NNCLEEBI_01359 9.26e-138 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
NNCLEEBI_01360 2.19e-123 ybcH - - D ko:K06889 - ko00000 Alpha beta
NNCLEEBI_01361 1.16e-05 - - - S - - - Protein of unknown function (DUF4044)
NNCLEEBI_01362 5.43e-196 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Amino acid kinase family
NNCLEEBI_01364 2.65e-82 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
NNCLEEBI_01365 3.67e-180 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NNCLEEBI_01366 1.05e-13 ftsL - - D - - - Essential cell division protein
NNCLEEBI_01367 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
NNCLEEBI_01368 3.64e-172 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NNCLEEBI_01369 4.21e-233 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NNCLEEBI_01370 2.47e-194 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NNCLEEBI_01371 8e-77 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NNCLEEBI_01372 6.07e-240 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NNCLEEBI_01373 4.52e-229 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NNCLEEBI_01374 8.14e-43 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NNCLEEBI_01375 8.19e-27 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
NNCLEEBI_01376 9.9e-105 ylmH - - S - - - S4 domain protein
NNCLEEBI_01377 3.98e-92 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
NNCLEEBI_01378 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NNCLEEBI_01379 1.57e-145 - - - L ko:K07484 - ko00000 Transposase IS66 family
NNCLEEBI_01380 3.12e-60 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
NNCLEEBI_01382 4.52e-131 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
NNCLEEBI_01383 2e-91 - - - O - - - ADP-ribosylglycohydrolase
NNCLEEBI_01385 1.29e-109 - - - C - - - Domain of unknown function (DUF4931)
NNCLEEBI_01386 1.37e-116 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
NNCLEEBI_01387 2e-66 - - - M - - - LysM domain protein
NNCLEEBI_01388 5.6e-25 - - - P - - - Rhodanese Homology Domain
NNCLEEBI_01389 2.79e-49 - - - M - - - LysM domain
NNCLEEBI_01390 8.1e-204 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
NNCLEEBI_01391 1.5e-243 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
NNCLEEBI_01392 5.29e-178 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
NNCLEEBI_01393 5.76e-256 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
NNCLEEBI_01394 5.71e-275 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter transmembrane region
NNCLEEBI_01395 4.59e-121 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NNCLEEBI_01396 7e-134 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
NNCLEEBI_01397 6.22e-197 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
NNCLEEBI_01398 2.51e-183 pbuO_1 - - S ko:K06901 - ko00000,ko02000 Permease family
NNCLEEBI_01399 2.85e-88 - - - L - - - Helicase C-terminal domain protein
NNCLEEBI_01400 0.0 galA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
NNCLEEBI_01401 2.74e-69 - - - S - - - Membrane
NNCLEEBI_01402 1.33e-113 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
NNCLEEBI_01403 1.72e-38 - - - L ko:K07483,ko:K07497 - ko00000 Helix-turn-helix domain
NNCLEEBI_01404 4.78e-79 - - - K - - - helix_turn_helix, arabinose operon control protein
NNCLEEBI_01406 3.21e-266 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
NNCLEEBI_01407 5.92e-33 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
NNCLEEBI_01408 3.28e-239 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NNCLEEBI_01409 2.75e-78 yokL3 - - J - - - Acetyltransferase (GNAT) domain
NNCLEEBI_01410 5.02e-144 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
NNCLEEBI_01411 7.47e-104 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
NNCLEEBI_01412 5.83e-82 - - - - - - - -
NNCLEEBI_01413 7.22e-227 rsmF - - J - - - NOL1 NOP2 sun family protein
NNCLEEBI_01414 4.37e-55 XK27_03150 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
NNCLEEBI_01416 1.13e-104 qorB 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NmrA-like family
NNCLEEBI_01417 7.27e-53 ywnA - - K - - - Transcriptional regulator
NNCLEEBI_01418 1.98e-42 - - - S - - - CHY zinc finger
NNCLEEBI_01419 1.61e-102 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding dehydrogenase
NNCLEEBI_01421 3.89e-31 - - - L - - - Conserved phage C-terminus (Phg_2220_C)
NNCLEEBI_01423 1.58e-51 - - - M - - - Acetyltransferase (GNAT) family
NNCLEEBI_01424 1.79e-92 cps2D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
NNCLEEBI_01425 1.48e-82 - - - H - - - Methyltransferase domain
NNCLEEBI_01433 3.02e-64 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
NNCLEEBI_01434 5.42e-38 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
NNCLEEBI_01435 4.7e-57 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
NNCLEEBI_01436 6.13e-21 - - - - - - - -
NNCLEEBI_01440 6.37e-88 - - - - - - - -
NNCLEEBI_01441 1.68e-125 ytlR - - I - - - Diacylglycerol kinase catalytic domain
NNCLEEBI_01442 4.46e-225 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
NNCLEEBI_01443 3.63e-155 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
NNCLEEBI_01444 4.03e-102 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NNCLEEBI_01445 6.04e-275 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NNCLEEBI_01446 6.85e-49 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NNCLEEBI_01447 2.77e-75 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NNCLEEBI_01448 3.13e-78 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NNCLEEBI_01449 1.14e-127 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
NNCLEEBI_01450 6.23e-76 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NNCLEEBI_01451 1.16e-67 - - - S - - - Protein of unknown function (DUF441)
NNCLEEBI_01452 3.74e-160 yitL - - S ko:K00243 - ko00000 S1 domain
NNCLEEBI_01453 8.46e-144 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
NNCLEEBI_01454 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
NNCLEEBI_01455 1.17e-98 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NNCLEEBI_01456 1.52e-236 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
NNCLEEBI_01457 1.31e-82 ypsA - - S - - - Belongs to the UPF0398 family
NNCLEEBI_01458 1.7e-245 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Adenine deaminase C-terminal domain
NNCLEEBI_01460 1.69e-93 - - - M - - - GNAT acetyltransferase
NNCLEEBI_01461 1.16e-87 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
NNCLEEBI_01462 1.34e-73 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
NNCLEEBI_01463 1.01e-52 - - - - - - - -
NNCLEEBI_01464 1.6e-12 - - - - - - - -
NNCLEEBI_01465 1.45e-78 - - - K - - - Transcriptional regulator
NNCLEEBI_01466 1.14e-18 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
NNCLEEBI_01467 7.75e-22 - - - K - - - Cro/C1-type HTH DNA-binding domain
NNCLEEBI_01468 0.0 - - - L - - - helicase superfamily c-terminal domain
NNCLEEBI_01469 1.17e-156 - - - L - - - helicase superfamily c-terminal domain
NNCLEEBI_01470 5.16e-128 - - - S - - - Domain of unknown function (DUF4391)
NNCLEEBI_01471 4.37e-183 mod 2.1.1.72 - L ko:K07316 - ko00000,ko01000,ko02048 PFAM DNA methylase N-4 N-6 domain protein
NNCLEEBI_01475 2.98e-67 mod 2.1.1.72 - L ko:K00571,ko:K07316 - ko00000,ko01000,ko02048 DNA methylase
NNCLEEBI_01476 3.07e-303 - - - L - - - Transposase
NNCLEEBI_01477 5.05e-168 - 2.1.1.72 - L ko:K07316 - ko00000,ko01000,ko02048 DNA methylase
NNCLEEBI_01478 0.0 XK27_03440 3.1.21.5 - L ko:K01156 - ko00000,ko01000,ko02048 Type III restriction enzyme, res subunit
NNCLEEBI_01480 1.71e-85 - - - E - - - Zn peptidase
NNCLEEBI_01481 1.39e-102 - - - F - - - Hydrolase, nudix family
NNCLEEBI_01483 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
NNCLEEBI_01484 1.54e-262 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
NNCLEEBI_01485 5.12e-90 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
NNCLEEBI_01486 6.63e-91 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
NNCLEEBI_01487 6.63e-167 - - - L - - - Belongs to the 'phage' integrase family
NNCLEEBI_01488 6.12e-83 - - - V - - - Type I restriction modification DNA specificity domain
NNCLEEBI_01489 3.8e-88 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NNCLEEBI_01490 1.88e-135 - - - E - - - Alpha/beta hydrolase of unknown function (DUF915)
NNCLEEBI_01491 4.75e-215 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
NNCLEEBI_01492 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
NNCLEEBI_01493 2.2e-264 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NNCLEEBI_01494 5.37e-237 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NNCLEEBI_01495 8.86e-277 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
NNCLEEBI_01496 1.2e-78 - - - S - - - Helix-turn-helix domain
NNCLEEBI_01497 1.14e-156 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
NNCLEEBI_01498 4.24e-27 - - - M - - - Lysin motif
NNCLEEBI_01499 3.58e-112 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
NNCLEEBI_01500 1.39e-104 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Ami_3
NNCLEEBI_01501 5.08e-197 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
NNCLEEBI_01502 2.42e-88 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NNCLEEBI_01503 5.92e-40 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
NNCLEEBI_01504 4.63e-199 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NNCLEEBI_01505 3.32e-115 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
NNCLEEBI_01507 2.17e-276 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NNCLEEBI_01508 2.62e-220 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
NNCLEEBI_01509 4.73e-40 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NNCLEEBI_01510 2.34e-191 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NNCLEEBI_01511 2.35e-76 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Low molecular weight phosphatase family
NNCLEEBI_01512 3.19e-220 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
NNCLEEBI_01513 7.87e-287 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
NNCLEEBI_01514 2.87e-48 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NNCLEEBI_01516 3.98e-26 - - - K - - - Psort location Cytoplasmic, score
NNCLEEBI_01517 2.82e-141 natA - - S ko:K01990 - ko00000,ko00002,ko02000 Domain of unknown function (DUF4162)
NNCLEEBI_01518 6.04e-103 natB - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-type Na efflux pump, permease component
NNCLEEBI_01519 2.08e-121 - - - EG - - - EamA-like transporter family
NNCLEEBI_01520 1.75e-99 - - - S - - - Calcineurin-like phosphoesterase
NNCLEEBI_01521 1.51e-235 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NNCLEEBI_01522 2.22e-52 - - - S - - - ASCH
NNCLEEBI_01523 1.94e-91 - 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase, peptidase S26
NNCLEEBI_01524 6.85e-147 - - - S - - - EDD domain protein, DegV family
NNCLEEBI_01525 2.07e-52 - - - K - - - Transcriptional regulator
NNCLEEBI_01526 3.3e-254 FbpA - - K - - - Fibronectin-binding protein
NNCLEEBI_01527 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NNCLEEBI_01528 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NNCLEEBI_01529 1.38e-106 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NNCLEEBI_01530 6.49e-53 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
NNCLEEBI_01532 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
NNCLEEBI_01533 1.7e-211 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NNCLEEBI_01534 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
NNCLEEBI_01535 6.47e-21 - - - S - - - Protein of unknown function (DUF2929)
NNCLEEBI_01536 0.0 clpB - - O ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NNCLEEBI_01537 1.08e-118 tnp2 - - L - - - Transposase
NNCLEEBI_01538 5.64e-256 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NNCLEEBI_01539 5.49e-54 XK27_04120 - - S - - - Putative amino acid metabolism
NNCLEEBI_01540 8.18e-202 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
NNCLEEBI_01541 2.65e-112 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NNCLEEBI_01543 1.21e-104 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
NNCLEEBI_01544 9.91e-165 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NNCLEEBI_01545 1.34e-220 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
NNCLEEBI_01546 1.24e-173 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
NNCLEEBI_01547 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NNCLEEBI_01548 2.7e-257 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
NNCLEEBI_01549 3.9e-190 XK27_05225 - - S - - - Tetratricopeptide repeat protein
NNCLEEBI_01550 2.44e-174 - - - EG - - - EamA-like transporter family
NNCLEEBI_01551 6.31e-93 - - - L - - - DNA alkylation repair enzyme
NNCLEEBI_01552 4.12e-231 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
NNCLEEBI_01553 1.15e-131 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NNCLEEBI_01554 6.85e-98 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
NNCLEEBI_01555 2.37e-184 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
NNCLEEBI_01559 2.15e-51 - - - - - - - -
NNCLEEBI_01560 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
NNCLEEBI_01561 4.15e-34 - - - S - - - Family of unknown function (DUF5322)
NNCLEEBI_01562 6.27e-48 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
NNCLEEBI_01563 2.69e-218 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
NNCLEEBI_01564 3.6e-57 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NNCLEEBI_01566 3.49e-111 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
NNCLEEBI_01567 4.96e-219 araT1 - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NNCLEEBI_01568 1.16e-147 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
NNCLEEBI_01569 1.09e-184 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
NNCLEEBI_01570 1.83e-172 - - - K - - - Transcriptional regulator
NNCLEEBI_01571 1.43e-112 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NNCLEEBI_01572 1.5e-109 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NNCLEEBI_01573 5.97e-237 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
NNCLEEBI_01574 1.29e-141 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
NNCLEEBI_01575 1.07e-256 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
NNCLEEBI_01576 2.49e-97 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NNCLEEBI_01577 3.4e-164 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
NNCLEEBI_01578 9.43e-57 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NNCLEEBI_01579 7.29e-72 yjcF - - J - - - HAD-hyrolase-like
NNCLEEBI_01580 3.59e-71 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NNCLEEBI_01581 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NNCLEEBI_01582 1.01e-95 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NNCLEEBI_01583 3.09e-149 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
NNCLEEBI_01584 5.19e-56 XK27_03960 - - S - - - Protein of unknown function (DUF3013)
NNCLEEBI_01585 1.76e-183 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
NNCLEEBI_01586 2.79e-17 - - - - - - - -
NNCLEEBI_01587 2e-88 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NNCLEEBI_01588 4.31e-127 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
NNCLEEBI_01589 2.68e-162 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NNCLEEBI_01590 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NNCLEEBI_01591 7.45e-220 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NNCLEEBI_01592 3.97e-56 yodB - - K - - - Transcriptional regulator, HxlR family
NNCLEEBI_01593 1.13e-87 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
NNCLEEBI_01594 4.67e-109 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NNCLEEBI_01597 8.63e-20 - - - - - - - -
NNCLEEBI_01599 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NNCLEEBI_01600 2.87e-48 - - - S - - - repeat protein
NNCLEEBI_01601 1.45e-129 pgm - - G - - - Phosphoglycerate mutase family
NNCLEEBI_01602 8.98e-193 - - - M ko:K01992 - ko00000,ko00002,ko02000 Exporter of polyketide antibiotics
NNCLEEBI_01603 5.46e-256 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system Galactitol-specific IIC component
NNCLEEBI_01604 4.05e-152 - - - L - - - Belongs to the 'phage' integrase family
NNCLEEBI_01605 1.59e-30 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
NNCLEEBI_01607 9.96e-59 - - - S - - - Phage regulatory protein Rha (Phage_pRha)
NNCLEEBI_01614 9.53e-25 - - - S - - - Bifunctional DNA primase/polymerase, N-terminal
NNCLEEBI_01615 1.34e-163 - - - S ko:K06919 - ko00000 D5 N terminal like
NNCLEEBI_01618 2.01e-264 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NNCLEEBI_01619 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NNCLEEBI_01620 1.38e-106 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
NNCLEEBI_01621 4.77e-123 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NNCLEEBI_01622 1.47e-169 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NNCLEEBI_01623 1.77e-33 yozE - - S - - - Belongs to the UPF0346 family
NNCLEEBI_01624 2.28e-68 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
NNCLEEBI_01625 2.64e-100 XK27_03630 - - E - - - GDSL-like Lipase/Acylhydrolase
NNCLEEBI_01627 1.11e-145 - - - L ko:K07484 - ko00000 Transposase IS66 family
NNCLEEBI_01628 3.12e-60 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
NNCLEEBI_01630 5.85e-71 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NNCLEEBI_01631 1.36e-200 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NNCLEEBI_01632 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
NNCLEEBI_01633 1.78e-168 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NNCLEEBI_01634 4.56e-137 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NNCLEEBI_01635 2.69e-142 ypjC - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
NNCLEEBI_01636 3.84e-87 - - - L - - - Phage integrase, N-terminal SAM-like domain
NNCLEEBI_01638 1.87e-75 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
NNCLEEBI_01639 5.93e-30 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
NNCLEEBI_01640 2.08e-148 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NNCLEEBI_01643 1.33e-127 - - - M - - - Glycosyltransferase like family 2
NNCLEEBI_01644 4.93e-106 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
NNCLEEBI_01645 2.3e-116 - - - M - - - transferase activity, transferring glycosyl groups
NNCLEEBI_01646 4.35e-160 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
NNCLEEBI_01647 7.32e-101 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NNCLEEBI_01648 2.19e-108 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NNCLEEBI_01649 8.95e-73 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
NNCLEEBI_01650 4.9e-300 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
NNCLEEBI_01651 7.4e-180 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
NNCLEEBI_01652 1.35e-46 ypmB - - S - - - Protein conserved in bacteria
NNCLEEBI_01653 2.01e-273 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
NNCLEEBI_01654 6.38e-120 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
NNCLEEBI_01655 3.59e-156 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
NNCLEEBI_01656 3.26e-172 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
NNCLEEBI_01657 3.51e-144 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NNCLEEBI_01658 2.94e-133 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
NNCLEEBI_01659 1.24e-186 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
NNCLEEBI_01660 1.71e-90 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
NNCLEEBI_01661 7.31e-63 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
NNCLEEBI_01662 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
NNCLEEBI_01663 8e-74 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
NNCLEEBI_01664 6.94e-28 - - - - - - - -
NNCLEEBI_01666 7.39e-156 - - - K - - - LysR substrate binding domain
NNCLEEBI_01667 6.83e-243 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NNCLEEBI_01668 3.68e-136 - - - S - - - Acyltransferase family
NNCLEEBI_01669 4.59e-201 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
NNCLEEBI_01670 6.93e-292 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
NNCLEEBI_01671 2.31e-94 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NNCLEEBI_01672 6.96e-175 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
NNCLEEBI_01673 3.54e-282 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NNCLEEBI_01674 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NNCLEEBI_01675 4.77e-132 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NNCLEEBI_01676 1.85e-40 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NNCLEEBI_01677 2.47e-122 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
NNCLEEBI_01678 1.08e-118 tnp2 - - L - - - Transposase
NNCLEEBI_01679 2.1e-166 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
NNCLEEBI_01680 3.35e-65 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NNCLEEBI_01681 1.67e-92 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
NNCLEEBI_01682 2.86e-24 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
NNCLEEBI_01683 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NNCLEEBI_01684 8.72e-126 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
NNCLEEBI_01685 2.92e-189 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
NNCLEEBI_01686 7.81e-147 manY - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
NNCLEEBI_01687 1.09e-187 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
NNCLEEBI_01688 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
NNCLEEBI_01689 2.01e-94 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
NNCLEEBI_01690 3.57e-33 yktA - - S - - - Belongs to the UPF0223 family
NNCLEEBI_01691 9.49e-22 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the LDH MDH superfamily
NNCLEEBI_01692 7.87e-111 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NNCLEEBI_01693 3.51e-33 - - - - - - - -
NNCLEEBI_01694 1.47e-30 ykzG - - S - - - Belongs to the UPF0356 family
NNCLEEBI_01695 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NNCLEEBI_01696 1.08e-118 tnp2 - - L - - - Transposase
NNCLEEBI_01697 3.87e-315 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NNCLEEBI_01698 3.67e-251 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NNCLEEBI_01699 2.37e-246 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NNCLEEBI_01700 6.83e-274 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NNCLEEBI_01701 0.00027 - - - S - - - Tetratricopeptide repeat
NNCLEEBI_01702 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NNCLEEBI_01703 7.62e-147 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NNCLEEBI_01704 2.6e-53 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NNCLEEBI_01705 1.33e-43 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
NNCLEEBI_01706 4.09e-108 sip - - L - - - Belongs to the 'phage' integrase family
NNCLEEBI_01710 3.23e-50 - - - K - - - Peptidase S24-like
NNCLEEBI_01712 1.45e-21 - - - K - - - Helix-turn-helix XRE-family like proteins
NNCLEEBI_01713 4.97e-97 - - - K ko:K07741 - ko00000 AntA/AntB antirepressor
NNCLEEBI_01719 1.21e-66 - - - S - - - Putative HNHc nuclease
NNCLEEBI_01720 1.04e-31 - - - L - - - N-terminal phage replisome organiser (Phage_rep_org_N)
NNCLEEBI_01723 5.93e-28 - - - - - - - -
NNCLEEBI_01731 1.56e-21 - - - S - - - protein disulfide oxidoreductase activity
NNCLEEBI_01742 5.87e-28 radC - - L ko:K03630 - ko00000 DNA repair protein
NNCLEEBI_01746 1.28e-07 - - - V - - - COG1403 Restriction endonuclease
NNCLEEBI_01747 1.15e-67 - - - L - - - Phage terminase, small subunit
NNCLEEBI_01748 0.0 terL - - S - - - overlaps another CDS with the same product name
NNCLEEBI_01749 2.14e-192 - - - S - - - Phage portal protein
NNCLEEBI_01750 1.35e-79 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
NNCLEEBI_01751 2.74e-147 - - - S - - - peptidase activity
NNCLEEBI_01752 3.95e-24 - - - S - - - Phage gp6-like head-tail connector protein
NNCLEEBI_01753 2.43e-30 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
NNCLEEBI_01755 3.75e-83 - - - - - - - -
NNCLEEBI_01756 4.14e-13 - - - - - - - -
NNCLEEBI_01758 6.27e-189 - - - L - - - Phage tail tape measure protein TP901
NNCLEEBI_01759 6.7e-23 - - - S - - - phage tail
NNCLEEBI_01760 3.74e-61 - - - M - - - Prophage endopeptidase tail
NNCLEEBI_01761 3.47e-09 - 3.2.1.22 - E ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 lipolytic protein G-D-S-L family
NNCLEEBI_01764 6.59e-26 - - - S - - - Bacteriophage holin of superfamily 6 (Holin_LLH)
NNCLEEBI_01765 1.84e-138 - - - M - - - lysozyme activity
NNCLEEBI_01766 1.9e-145 - - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
NNCLEEBI_01767 0.0 - - - M ko:K01992 - ko00000,ko00002,ko02000 Exporter of polyketide antibiotics
NNCLEEBI_01768 3.74e-212 ybhF_1 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NNCLEEBI_01770 4.51e-120 - - - S - - - MobA/MobL family
NNCLEEBI_01772 2.26e-66 repB - - L - - - Initiator Replication protein
NNCLEEBI_01774 9.83e-115 - - - EGP - - - Major Facilitator Superfamily
NNCLEEBI_01775 2.14e-111 cylA - - V ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
NNCLEEBI_01776 3.32e-128 pinR1 - - L - - - Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
NNCLEEBI_01777 1.9e-145 - - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
NNCLEEBI_01778 0.0 - - - M ko:K01992 - ko00000,ko00002,ko02000 Exporter of polyketide antibiotics
NNCLEEBI_01779 3.74e-212 ybhF_1 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NNCLEEBI_01781 4.51e-120 - - - S - - - MobA/MobL family
NNCLEEBI_01783 2.26e-66 repB - - L - - - Initiator Replication protein
NNCLEEBI_01785 9.83e-115 - - - EGP - - - Major Facilitator Superfamily
NNCLEEBI_01786 2.14e-111 cylA - - V ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
NNCLEEBI_01787 4.41e-86 pinR1 - - L - - - Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
NNCLEEBI_01788 1.06e-36 - - - K - - - Helix-turn-helix XRE-family like proteins
NNCLEEBI_01789 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
NNCLEEBI_01790 1.2e-99 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Restriction endonuclease S subunits
NNCLEEBI_01791 7.15e-161 - - - L - - - Belongs to the 'phage' integrase family
NNCLEEBI_01792 6.03e-38 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 COG0732 Restriction endonuclease S subunits
NNCLEEBI_01793 4.08e-56 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
NNCLEEBI_01794 8.48e-312 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
NNCLEEBI_01795 2.41e-71 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
NNCLEEBI_01797 3.83e-173 pfoS/R - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
NNCLEEBI_01798 4.45e-147 ddh 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NNCLEEBI_01799 2.06e-16 - - - M - - - by MetaGeneAnnotator
NNCLEEBI_01801 5.07e-68 - - - S - - - EVIDENCE BY HOMOLOGY BIO14.03 Phage related functions and prophages
NNCLEEBI_01802 1.05e-59 - - - L - - - Phage tail tape measure protein TP901
NNCLEEBI_01807 1.08e-112 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
NNCLEEBI_01808 4.27e-39 - - - L ko:K07483,ko:K07497 - ko00000 Helix-turn-helix domain
NNCLEEBI_01809 4.13e-35 - - - S - - - Phage minor capsid protein 2
NNCLEEBI_01810 1.87e-126 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Nitronate monooxygenase
NNCLEEBI_01811 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
NNCLEEBI_01813 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 phosphatase activity
NNCLEEBI_01814 5.08e-89 - - - L - - - Phage integrase, N-terminal SAM-like domain
NNCLEEBI_01816 3.88e-18 - - - - - - - -
NNCLEEBI_01817 6.37e-122 - - - L - - - Probable transposase
NNCLEEBI_01818 2.95e-37 - - - - - - - -
NNCLEEBI_01821 4.27e-39 - - - L ko:K07483,ko:K07497 - ko00000 Helix-turn-helix domain
NNCLEEBI_01822 1.08e-112 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
NNCLEEBI_01823 3.22e-35 - - - S - - - Phage Mu protein F like protein
NNCLEEBI_01824 2.86e-07 - - - L ko:K07474 - ko00000 Terminase small subunit
NNCLEEBI_01826 3.15e-67 - - - K - - - Domain of unknown function (DUF4417)
NNCLEEBI_01829 1.12e-19 - - - S - - - Phage transcriptional regulator, ArpU family
NNCLEEBI_01831 2.58e-19 - - - K - - - ORF6N domain
NNCLEEBI_01832 7.15e-07 ansR - - K - - - transcriptional
NNCLEEBI_01833 5.78e-34 - - - K - - - Helix-turn-helix XRE-family like proteins
NNCLEEBI_01835 4.66e-32 - - - - - - - -
NNCLEEBI_01836 9.3e-67 sip - - L - - - Belongs to the 'phage' integrase family
NNCLEEBI_01837 1.1e-234 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NNCLEEBI_01838 2.66e-102 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
NNCLEEBI_01839 2.76e-87 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
NNCLEEBI_01840 5.79e-54 yitW - - S - - - Iron-sulfur cluster assembly protein
NNCLEEBI_01841 1.05e-143 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
NNCLEEBI_01842 2.72e-96 - 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
NNCLEEBI_01843 2.52e-119 nanB 3.2.1.18 GH33 G ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 ko00000,ko00001,ko01000,ko02042 BNR repeat-like domain
NNCLEEBI_01844 6.72e-106 nanB 3.2.1.18 GH33 G ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 ko00000,ko00001,ko01000,ko02042 BNR repeat-like domain
NNCLEEBI_01846 1.24e-252 gph - - G ko:K03292 - ko00000 MFS/sugar transport protein
NNCLEEBI_01847 4e-229 - - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
NNCLEEBI_01848 7.33e-48 - - - G - - - single-species biofilm formation
NNCLEEBI_01849 4.37e-70 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
NNCLEEBI_01850 1.77e-115 nanK - - GK - - - ROK family
NNCLEEBI_01851 4.39e-162 nanA 4.1.3.3 - EM ko:K01639 ko00520,map00520 ko00000,ko00001,ko01000 Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
NNCLEEBI_01852 5.09e-118 nanE 5.1.3.9 - G ko:K01788 ko00520,map00520 ko00000,ko00001,ko01000 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
NNCLEEBI_01853 4.68e-95 - - - K - - - Helix-turn-helix domain, rpiR family
NNCLEEBI_01854 1.31e-45 yphA - - GM - - - NAD dependent epimerase/dehydratase family
NNCLEEBI_01855 3.57e-270 potE - - E - - - Amino Acid
NNCLEEBI_01856 1.16e-08 - - - - - - - -
NNCLEEBI_01857 5.44e-43 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NNCLEEBI_01858 2.28e-293 fusA1 - - J - - - elongation factor G
NNCLEEBI_01861 6.37e-72 - - - L - - - PLD-like domain
NNCLEEBI_01862 4.11e-53 - - - L - - - PLD-like domain
NNCLEEBI_01863 3.07e-303 - - - L - - - Transposase
NNCLEEBI_01864 1.33e-23 - - - - - - - -
NNCLEEBI_01865 1.82e-173 ermA 2.1.1.184 - J ko:K00561 - br01600,ko00000,ko01000,ko01504,ko03009 Ribosomal RNA adenine dimethylase
NNCLEEBI_01866 4.67e-64 - - - L - - - PLD-like domain
NNCLEEBI_01869 9.27e-142 - - - L - - - Initiator Replication protein
NNCLEEBI_01870 1.88e-45 - - - S - - - Replication initiator protein A (RepA) N-terminus
NNCLEEBI_01871 3.62e-121 - - - L - - - Probable transposase
NNCLEEBI_01872 3.22e-78 - - - L - - - Resolvase, N-terminal domain
NNCLEEBI_01873 8.68e-15 bglG - - K ko:K03488 - ko00000,ko03000 antiterminator
NNCLEEBI_01874 3.22e-161 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
NNCLEEBI_01876 7.76e-48 - - - - - - - -
NNCLEEBI_01877 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
NNCLEEBI_01878 3.83e-48 - - - - - - - -
NNCLEEBI_01879 2.24e-92 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NNCLEEBI_01880 2.15e-69 arsB - - P ko:K03325 - ko00000,ko02000 Sodium Bile acid symporter family
NNCLEEBI_01882 3.36e-127 - - - P - - - cadmium resistance
NNCLEEBI_01888 6.59e-22 - - - - - - - -
NNCLEEBI_01890 4.52e-11 - - - - - - - -
NNCLEEBI_01893 8.41e-142 yvgN - - C - - - Aldo keto reductase
NNCLEEBI_01894 8.3e-08 yvgN - - C - - - Aldo keto reductase
NNCLEEBI_01895 8.67e-36 - - - S ko:K07089 - ko00000 Predicted permease
NNCLEEBI_01896 3.06e-49 - - - S ko:K07089 - ko00000 Predicted permease
NNCLEEBI_01897 4.48e-86 - - - L ko:K07497 - ko00000 hmm pf00665
NNCLEEBI_01899 2.89e-240 XK27_11280 - - S - - - Psort location CytoplasmicMembrane, score
NNCLEEBI_01901 2e-136 - - - L - - - Belongs to the 'phage' integrase family
NNCLEEBI_01903 1.78e-60 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
NNCLEEBI_01905 2.55e-206 - - - L - - - T/G mismatch-specific endonuclease activity
NNCLEEBI_01906 5.72e-76 - - - - - - - -
NNCLEEBI_01907 7.22e-85 - - - - - - - -
NNCLEEBI_01908 3.16e-72 - - - V - - - Type II restriction enzyme, methylase subunits
NNCLEEBI_01909 1.96e-15 - - - V - - - Type II restriction enzyme, methylase subunits
NNCLEEBI_01910 1.58e-304 yeeA - - V - - - Type II restriction enzyme, methylase subunits
NNCLEEBI_01911 0.0 - - - L - - - DEAD-like helicases superfamily
NNCLEEBI_01912 2.16e-118 yeeC - - P - - - T5orf172
NNCLEEBI_01914 2.58e-16 - - - - - - - -
NNCLEEBI_01917 1.02e-102 potE2 - - E ko:K03294 - ko00000 amino acid
NNCLEEBI_01918 2.72e-148 queH 1.17.99.6 - C ko:K09765 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NNCLEEBI_01919 5.36e-74 - - - K - - - Domain of unknown function (DUF1836)
NNCLEEBI_01920 8.9e-105 yitS - - S - - - EDD domain protein, DegV family
NNCLEEBI_01921 4.33e-48 - - - S - - - Enterocin A Immunity
NNCLEEBI_01922 1.73e-49 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NNCLEEBI_01923 0.0 prtB 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NNCLEEBI_01924 1.23e-34 - - - S - - - protein encoded in hypervariable junctions of pilus gene clusters
NNCLEEBI_01925 3.22e-140 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
NNCLEEBI_01926 4.59e-16 - - - S - - - YjcQ protein
NNCLEEBI_01927 3.03e-67 - - - C - - - Oxidoreductase NAD-binding domain
NNCLEEBI_01928 8.55e-76 - - - L ko:K07491 - ko00000 Transposase IS200 like
NNCLEEBI_01929 1.29e-200 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
NNCLEEBI_01930 3.88e-71 - - - L ko:K07491 - ko00000 Transposase IS200 like
NNCLEEBI_01931 5.26e-111 - - - L ko:K07496 - ko00000 Transposase, IS605 OrfB family
NNCLEEBI_01932 4.21e-90 - - - EGP - - - Major Facilitator Superfamily
NNCLEEBI_01933 6.52e-90 - - - K - - - Transcriptional regulator, LysR family
NNCLEEBI_01934 7.4e-177 - - - G - - - Xylose isomerase-like TIM barrel
NNCLEEBI_01935 1.65e-146 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
NNCLEEBI_01936 5.94e-271 - 1.3.5.1, 1.3.5.4 - C ko:K00239,ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134 ko00000,ko00001,ko00002,ko01000 FAD binding domain
NNCLEEBI_01937 8.49e-175 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NNCLEEBI_01938 4.56e-89 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NNCLEEBI_01939 4.43e-181 xerS - - L ko:K04763 - ko00000,ko03036 Phage integrase family
NNCLEEBI_01940 4.29e-16 - - - - - - - -
NNCLEEBI_01941 7.88e-42 - - - - - - - -
NNCLEEBI_01942 1.73e-18 - - - S - - - YjcQ protein
NNCLEEBI_01945 4.38e-130 bsh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
NNCLEEBI_01946 2.63e-89 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
NNCLEEBI_01947 1.23e-99 desR - - K ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, Lux Regulon
NNCLEEBI_01948 2.17e-73 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NNCLEEBI_01949 1.61e-65 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
NNCLEEBI_01950 2.09e-101 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NNCLEEBI_01953 1.22e-08 yhaH - - S - - - Protein of unknown function (DUF805)
NNCLEEBI_01954 6.96e-12 - - - S - - - Protein of unknown function (DUF805)
NNCLEEBI_01955 8.44e-12 - - - S - - - Protein of unknown function (DUF805)
NNCLEEBI_01957 1.22e-12 - - - L - - - Belongs to the 'phage' integrase family
NNCLEEBI_01958 6.66e-126 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NNCLEEBI_01959 1.01e-99 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
NNCLEEBI_01960 5.04e-21 - - - - - - - -
NNCLEEBI_01961 3.14e-78 - - - V - - - endonuclease activity
NNCLEEBI_01963 3.76e-18 - - - - - - - -
NNCLEEBI_01964 1.07e-141 rssA - - S - - - Phospholipase, patatin family
NNCLEEBI_01965 1.57e-174 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NNCLEEBI_01966 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
NNCLEEBI_01967 1.65e-64 - - - S - - - VIT family
NNCLEEBI_01968 2.63e-30 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
NNCLEEBI_01969 1.85e-262 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
NNCLEEBI_01970 1.15e-53 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
NNCLEEBI_01971 1.2e-183 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NNCLEEBI_01972 2.26e-181 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
NNCLEEBI_01973 2.13e-147 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
NNCLEEBI_01974 1.56e-281 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
NNCLEEBI_01976 1.32e-39 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
NNCLEEBI_01977 3.08e-99 - - - L ko:K07484 - ko00000 Transposase IS66 family
NNCLEEBI_01978 8.9e-30 - - - L ko:K07484 - ko00000 Transposase IS66 family

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)