ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
IAJLEBKO_00001 1.63e-261 xkdO - - L - - - Transglycosylase SLT domain
IAJLEBKO_00002 6.56e-145 xkdP - - S - - - Lysin motif
IAJLEBKO_00003 2.66e-206 xkdQ - - G - - - NLP P60 protein
IAJLEBKO_00004 2.51e-43 xkdR - - S - - - Protein of unknown function (DUF2577)
IAJLEBKO_00005 9.98e-77 xkdS - - S - - - Protein of unknown function (DUF2634)
IAJLEBKO_00006 1.08e-212 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
IAJLEBKO_00007 2.03e-112 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
IAJLEBKO_00008 3.63e-37 - - - - - - - -
IAJLEBKO_00009 7.89e-111 - - - - - - - -
IAJLEBKO_00011 1.55e-38 xkdX - - - - - - -
IAJLEBKO_00012 6.09e-176 xepA - - - - - - -
IAJLEBKO_00013 3.87e-51 xhlA - - S - - - Haemolysin XhlA
IAJLEBKO_00014 4.7e-52 xhlB - - S - - - SPP1 phage holin
IAJLEBKO_00015 6.03e-216 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
IAJLEBKO_00016 2.53e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
IAJLEBKO_00017 7.37e-170 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
IAJLEBKO_00018 7.07e-226 pit - - P ko:K03306 - ko00000 phosphate transporter
IAJLEBKO_00019 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
IAJLEBKO_00020 9.38e-312 steT - - E ko:K03294 - ko00000 amino acid
IAJLEBKO_00021 6.1e-228 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
IAJLEBKO_00022 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IAJLEBKO_00023 5.21e-228 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
IAJLEBKO_00025 7.53e-276 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IAJLEBKO_00026 0.0 yubD - - P - - - Major Facilitator Superfamily
IAJLEBKO_00027 5.09e-199 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
IAJLEBKO_00028 2.3e-203 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAJLEBKO_00029 1.89e-226 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAJLEBKO_00030 9.2e-243 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IAJLEBKO_00031 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
IAJLEBKO_00032 1.38e-226 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
IAJLEBKO_00033 3.53e-254 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
IAJLEBKO_00034 7.32e-216 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
IAJLEBKO_00035 6.62e-231 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IAJLEBKO_00036 3.43e-262 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
IAJLEBKO_00037 2.42e-203 ykgA - - E - - - Amidinotransferase
IAJLEBKO_00038 2.16e-120 ykhA - - I - - - Acyl-CoA hydrolase
IAJLEBKO_00039 2.59e-130 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IAJLEBKO_00040 3.36e-68 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
IAJLEBKO_00041 1.17e-62 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
IAJLEBKO_00042 1.66e-217 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
IAJLEBKO_00043 4.17e-260 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IAJLEBKO_00044 2.18e-287 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IAJLEBKO_00045 4.65e-91 ohrA - - O - - - Organic hydroperoxide resistance protein
IAJLEBKO_00046 2.85e-99 ohrR - - K - - - COG1846 Transcriptional regulators
IAJLEBKO_00047 1.92e-92 ohrB - - O - - - Organic hydroperoxide resistance protein
IAJLEBKO_00048 4.03e-76 - - - D - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IAJLEBKO_00050 5.84e-274 - - - M - - - Glycosyl transferase family 2
IAJLEBKO_00051 1.55e-170 - - - M - - - PFAM Collagen triple helix repeat (20 copies)
IAJLEBKO_00052 4.45e-274 - - - EGP ko:K05820 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
IAJLEBKO_00053 8.51e-157 nsr - - T - - - COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
IAJLEBKO_00054 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IAJLEBKO_00055 7.39e-226 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
IAJLEBKO_00056 1.05e-188 yojH - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IAJLEBKO_00057 6.53e-171 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
IAJLEBKO_00058 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
IAJLEBKO_00059 2.31e-126 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
IAJLEBKO_00060 1.04e-308 ydhD - - M - - - Glycosyl hydrolase
IAJLEBKO_00062 2.89e-308 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
IAJLEBKO_00063 1.23e-69 tnrA - - K - - - transcriptional
IAJLEBKO_00064 1.11e-23 - - - - - - - -
IAJLEBKO_00065 5.25e-37 ykoL - - - - - - -
IAJLEBKO_00066 1.1e-104 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
IAJLEBKO_00067 7.68e-129 ykoP - - G - - - polysaccharide deacetylase
IAJLEBKO_00068 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
IAJLEBKO_00069 3.83e-199 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
IAJLEBKO_00070 7.92e-129 ykoX - - S - - - membrane-associated protein
IAJLEBKO_00071 1.38e-171 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
IAJLEBKO_00072 6.02e-163 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IAJLEBKO_00073 6.31e-231 ykrI - - S - - - Anti-sigma factor N-terminus
IAJLEBKO_00074 5.7e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
IAJLEBKO_00075 9.35e-161 ykrK - - S - - - Domain of unknown function (DUF1836)
IAJLEBKO_00076 1.05e-198 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
IAJLEBKO_00077 3.8e-308 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
IAJLEBKO_00078 1.66e-145 - - - S - - - Protein of unknown function (DUF421)
IAJLEBKO_00079 1.78e-31 ykzE - - - - - - -
IAJLEBKO_00080 1.52e-240 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
IAJLEBKO_00081 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IAJLEBKO_00082 6.51e-114 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IAJLEBKO_00084 1.09e-251 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
IAJLEBKO_00085 2.34e-285 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
IAJLEBKO_00086 1.64e-192 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IAJLEBKO_00087 6.03e-290 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
IAJLEBKO_00088 4.53e-288 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
IAJLEBKO_00089 4.33e-171 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
IAJLEBKO_00090 1.51e-145 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
IAJLEBKO_00091 6.12e-123 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
IAJLEBKO_00093 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
IAJLEBKO_00094 3.91e-100 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
IAJLEBKO_00095 4.04e-169 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
IAJLEBKO_00096 4.74e-176 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
IAJLEBKO_00097 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
IAJLEBKO_00098 4.26e-229 ykvI - - S - - - membrane
IAJLEBKO_00099 1.36e-246 - - - - - - - -
IAJLEBKO_00100 2.72e-162 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IAJLEBKO_00101 1.26e-102 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
IAJLEBKO_00102 5.06e-179 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
IAJLEBKO_00103 2.56e-124 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IAJLEBKO_00104 2.54e-60 ykvR - - S - - - Protein of unknown function (DUF3219)
IAJLEBKO_00105 5.43e-35 ykvS - - S - - - protein conserved in bacteria
IAJLEBKO_00106 2.92e-38 - - - - - - - -
IAJLEBKO_00107 5.92e-142 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
IAJLEBKO_00108 7.63e-306 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IAJLEBKO_00109 1.22e-113 stoA - - CO - - - thiol-disulfide
IAJLEBKO_00110 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
IAJLEBKO_00111 5.5e-262 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
IAJLEBKO_00113 3.93e-222 ykvZ - - K - - - Transcriptional regulator
IAJLEBKO_00114 3.95e-199 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
IAJLEBKO_00115 0.0 ptsG 2.7.1.199 - G ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IAJLEBKO_00116 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
IAJLEBKO_00117 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IAJLEBKO_00118 3.63e-50 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
IAJLEBKO_00119 4.12e-255 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
IAJLEBKO_00120 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IAJLEBKO_00121 8.11e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
IAJLEBKO_00122 1.23e-147 ykwD - - J - - - protein with SCP PR1 domains
IAJLEBKO_00123 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
IAJLEBKO_00124 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IAJLEBKO_00125 1.62e-275 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
IAJLEBKO_00126 6.38e-15 - - - - - - - -
IAJLEBKO_00127 1.93e-213 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
IAJLEBKO_00128 5.07e-108 ykyB - - S - - - YkyB-like protein
IAJLEBKO_00129 4.41e-306 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
IAJLEBKO_00130 8.88e-117 ykuD - - S - - - protein conserved in bacteria
IAJLEBKO_00131 8.63e-196 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
IAJLEBKO_00132 1.06e-181 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IAJLEBKO_00134 3.67e-295 ykuI - - T - - - Diguanylate phosphodiesterase
IAJLEBKO_00135 3.63e-50 ykuJ - - S - - - protein conserved in bacteria
IAJLEBKO_00136 2.52e-119 ykuK - - S ko:K09776 - ko00000 Ribonuclease H-like
IAJLEBKO_00137 3.09e-35 ykzF - - S - - - Antirepressor AbbA
IAJLEBKO_00138 8.55e-99 ykuL - - S - - - CBS domain
IAJLEBKO_00139 5.36e-215 ccpC - - K - - - Transcriptional regulator
IAJLEBKO_00140 1.83e-116 ykuN - - C ko:K03839 - ko00000 Flavodoxin
IAJLEBKO_00141 2.35e-211 ykuO - - - - - - -
IAJLEBKO_00142 5.1e-102 fld - - C ko:K03839 - ko00000 Flavodoxin
IAJLEBKO_00143 2.89e-129 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IAJLEBKO_00144 3.25e-275 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IAJLEBKO_00145 2.15e-52 ykuS - - S - - - Belongs to the UPF0180 family
IAJLEBKO_00146 1.48e-179 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
IAJLEBKO_00147 2.51e-98 ykuV - - CO - - - thiol-disulfide
IAJLEBKO_00148 3.04e-126 rok - - K - - - Repressor of ComK
IAJLEBKO_00149 1.98e-215 yknT - - - ko:K06437 - ko00000 -
IAJLEBKO_00150 6.72e-140 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
IAJLEBKO_00151 9.91e-241 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IAJLEBKO_00152 3.24e-308 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
IAJLEBKO_00153 3.6e-119 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
IAJLEBKO_00154 8.37e-108 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
IAJLEBKO_00155 3.43e-45 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IAJLEBKO_00156 2.24e-131 yknW - - S - - - Yip1 domain
IAJLEBKO_00157 2.27e-236 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IAJLEBKO_00158 1.96e-156 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IAJLEBKO_00159 3.47e-268 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
IAJLEBKO_00160 1.32e-169 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
IAJLEBKO_00161 4.75e-214 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
IAJLEBKO_00162 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
IAJLEBKO_00163 3.77e-138 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
IAJLEBKO_00164 4.3e-49 ykoA - - - - - - -
IAJLEBKO_00165 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IAJLEBKO_00166 4.91e-211 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IAJLEBKO_00167 1.34e-299 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
IAJLEBKO_00168 4.47e-18 - - - S - - - Uncharacterized protein YkpC
IAJLEBKO_00169 3.72e-235 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
IAJLEBKO_00170 7.46e-59 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
IAJLEBKO_00171 1.61e-310 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
IAJLEBKO_00172 4.85e-193 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
IAJLEBKO_00173 9.71e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
IAJLEBKO_00174 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IAJLEBKO_00175 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IAJLEBKO_00176 4.45e-42 ykzG - - S - - - Belongs to the UPF0356 family
IAJLEBKO_00177 2.5e-186 ykrA - - S - - - hydrolases of the HAD superfamily
IAJLEBKO_00178 1.14e-130 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IAJLEBKO_00179 1.21e-06 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
IAJLEBKO_00180 5.36e-132 ykyA - - L - - - Putative cell-wall binding lipoprotein
IAJLEBKO_00181 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
IAJLEBKO_00182 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IAJLEBKO_00183 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 polyketide synthase
IAJLEBKO_00184 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IAJLEBKO_00185 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IAJLEBKO_00186 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IAJLEBKO_00187 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IAJLEBKO_00188 0.0 - - - IQ - - - Phosphopantetheine attachment site
IAJLEBKO_00189 4.54e-265 - - - V - - - Beta-lactamase
IAJLEBKO_00190 7.79e-261 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IAJLEBKO_00191 1.01e-226 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IAJLEBKO_00192 1.4e-299 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IAJLEBKO_00193 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IAJLEBKO_00194 3.24e-58 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
IAJLEBKO_00195 6.32e-186 pdaA_2 3.5.1.104 - G ko:K01567,ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
IAJLEBKO_00196 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
IAJLEBKO_00197 1.9e-56 yktA - - S - - - Belongs to the UPF0223 family
IAJLEBKO_00198 3.32e-154 yktB - - S - - - Belongs to the UPF0637 family
IAJLEBKO_00199 7.89e-32 ykzI - - - - - - -
IAJLEBKO_00200 3.31e-195 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
IAJLEBKO_00201 1.86e-49 ykzC - - S - - - Acetyltransferase (GNAT) family
IAJLEBKO_00202 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
IAJLEBKO_00204 6.1e-59 ylaE - - - - - - -
IAJLEBKO_00205 3.26e-32 - - - S - - - Family of unknown function (DUF5325)
IAJLEBKO_00206 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
IAJLEBKO_00207 4.05e-64 - - - S - - - YlaH-like protein
IAJLEBKO_00208 1.37e-45 ylaI - - S - - - protein conserved in bacteria
IAJLEBKO_00209 1.83e-136 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IAJLEBKO_00210 1.01e-308 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
IAJLEBKO_00211 1.18e-108 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IAJLEBKO_00212 1.81e-221 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
IAJLEBKO_00213 1.99e-58 ylaN - - S - - - Belongs to the UPF0358 family
IAJLEBKO_00214 2.02e-270 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
IAJLEBKO_00215 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IAJLEBKO_00216 3.47e-214 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
IAJLEBKO_00217 2.07e-209 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
IAJLEBKO_00218 3.95e-251 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
IAJLEBKO_00219 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IAJLEBKO_00220 2.41e-141 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
IAJLEBKO_00221 3.97e-66 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
IAJLEBKO_00222 3.45e-210 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
IAJLEBKO_00223 1.68e-78 ylbA - - S - - - YugN-like family
IAJLEBKO_00224 3.35e-96 ylbB - - T - - - COG0517 FOG CBS domain
IAJLEBKO_00225 3.26e-254 ylbC - - S - - - protein with SCP PR1 domains
IAJLEBKO_00226 6.69e-84 ylbD - - S - - - Putative coat protein
IAJLEBKO_00227 1.73e-48 ylbE - - S - - - YlbE-like protein
IAJLEBKO_00228 3.33e-97 ylbF - - S - - - Belongs to the UPF0342 family
IAJLEBKO_00229 5.61e-57 ylbG - - S - - - UPF0298 protein
IAJLEBKO_00231 1.01e-124 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
IAJLEBKO_00232 6.83e-109 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IAJLEBKO_00233 4.16e-275 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
IAJLEBKO_00234 2.48e-178 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
IAJLEBKO_00235 6.2e-240 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
IAJLEBKO_00236 8.29e-292 ylbM - - S - - - Belongs to the UPF0348 family
IAJLEBKO_00237 4.69e-115 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
IAJLEBKO_00238 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
IAJLEBKO_00239 3.13e-111 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
IAJLEBKO_00240 1.89e-115 ylbP - - K - - - n-acetyltransferase
IAJLEBKO_00241 1.68e-210 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IAJLEBKO_00242 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
IAJLEBKO_00243 9.07e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
IAJLEBKO_00244 1.66e-218 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IAJLEBKO_00245 2.4e-68 ftsL - - D - - - Essential cell division protein
IAJLEBKO_00246 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
IAJLEBKO_00247 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
IAJLEBKO_00248 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IAJLEBKO_00249 7.04e-222 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IAJLEBKO_00250 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IAJLEBKO_00251 2.7e-236 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
IAJLEBKO_00252 5.69e-259 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IAJLEBKO_00253 7.87e-213 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
IAJLEBKO_00254 1.04e-176 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IAJLEBKO_00255 1.57e-298 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IAJLEBKO_00256 2.61e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IAJLEBKO_00257 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
IAJLEBKO_00258 4.56e-215 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
IAJLEBKO_00259 7.35e-161 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IAJLEBKO_00260 9.33e-179 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IAJLEBKO_00261 2.21e-184 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
IAJLEBKO_00262 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
IAJLEBKO_00263 7.13e-52 ylmC - - S - - - sporulation protein
IAJLEBKO_00264 9.55e-206 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
IAJLEBKO_00265 1.05e-160 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IAJLEBKO_00266 4.61e-85 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IAJLEBKO_00267 5.12e-56 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
IAJLEBKO_00268 5.03e-181 ylmH - - S - - - conserved protein, contains S4-like domain
IAJLEBKO_00269 1.85e-99 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
IAJLEBKO_00270 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IAJLEBKO_00271 4.75e-80 ylyA - - T - - - COG1734 DnaK suppressor protein
IAJLEBKO_00272 1.24e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IAJLEBKO_00273 6.24e-215 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
IAJLEBKO_00274 2.21e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IAJLEBKO_00275 3.28e-295 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
IAJLEBKO_00276 2.44e-212 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
IAJLEBKO_00277 7.41e-313 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IAJLEBKO_00278 3.09e-268 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
IAJLEBKO_00279 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
IAJLEBKO_00280 7.44e-183 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
IAJLEBKO_00281 1.22e-220 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IAJLEBKO_00282 1.74e-161 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IAJLEBKO_00283 1.49e-147 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IAJLEBKO_00285 4.03e-180 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
IAJLEBKO_00286 3.87e-225 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
IAJLEBKO_00287 1.77e-283 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
IAJLEBKO_00288 9.22e-141 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
IAJLEBKO_00289 2.81e-183 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
IAJLEBKO_00290 1.14e-184 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
IAJLEBKO_00291 2.01e-102 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
IAJLEBKO_00292 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
IAJLEBKO_00293 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
IAJLEBKO_00294 2.5e-197 yloC - - S - - - stress-induced protein
IAJLEBKO_00295 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
IAJLEBKO_00296 4.91e-144 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
IAJLEBKO_00297 2.53e-38 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IAJLEBKO_00298 1.08e-287 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IAJLEBKO_00299 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IAJLEBKO_00300 1.18e-109 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IAJLEBKO_00301 6.21e-220 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IAJLEBKO_00302 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IAJLEBKO_00303 1.52e-263 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
IAJLEBKO_00304 1.17e-176 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
IAJLEBKO_00305 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
IAJLEBKO_00306 2.53e-210 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IAJLEBKO_00307 1.4e-150 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
IAJLEBKO_00308 1.3e-153 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
IAJLEBKO_00309 3.49e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
IAJLEBKO_00310 3.65e-78 yloU - - S - - - protein conserved in bacteria
IAJLEBKO_00311 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
IAJLEBKO_00312 4.15e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
IAJLEBKO_00313 2.4e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
IAJLEBKO_00314 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IAJLEBKO_00315 4.38e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
IAJLEBKO_00316 3.14e-229 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IAJLEBKO_00317 3.76e-218 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
IAJLEBKO_00318 8.61e-168 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
IAJLEBKO_00319 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
IAJLEBKO_00320 1.43e-172 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IAJLEBKO_00321 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
IAJLEBKO_00322 1.87e-224 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IAJLEBKO_00323 5.87e-180 - - - S - - - Phosphotransferase enzyme family
IAJLEBKO_00324 1.97e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IAJLEBKO_00325 9.92e-302 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IAJLEBKO_00326 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
IAJLEBKO_00327 4.9e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
IAJLEBKO_00328 3.41e-80 ylqD - - S - - - YlqD protein
IAJLEBKO_00329 1.51e-121 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IAJLEBKO_00330 5.67e-176 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
IAJLEBKO_00331 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IAJLEBKO_00332 4.19e-202 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IAJLEBKO_00333 6.81e-174 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IAJLEBKO_00334 0.0 ylqG - - - - - - -
IAJLEBKO_00335 6.94e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
IAJLEBKO_00336 2.02e-270 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
IAJLEBKO_00337 7.59e-214 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IAJLEBKO_00338 2.1e-215 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
IAJLEBKO_00339 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IAJLEBKO_00340 1.1e-313 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IAJLEBKO_00341 6.29e-220 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
IAJLEBKO_00342 7.38e-121 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IAJLEBKO_00343 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IAJLEBKO_00344 2.77e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
IAJLEBKO_00345 2.8e-84 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
IAJLEBKO_00346 2.63e-99 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
IAJLEBKO_00347 1.51e-50 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
IAJLEBKO_00348 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
IAJLEBKO_00349 2.48e-229 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
IAJLEBKO_00350 3.1e-119 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
IAJLEBKO_00351 3e-308 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
IAJLEBKO_00352 2.17e-92 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
IAJLEBKO_00353 1.98e-88 ylxF - - S - - - MgtE intracellular N domain
IAJLEBKO_00354 4.96e-259 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
IAJLEBKO_00355 1.8e-95 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
IAJLEBKO_00356 4.62e-178 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
IAJLEBKO_00357 6.59e-81 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
IAJLEBKO_00358 5.43e-230 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
IAJLEBKO_00359 6.97e-247 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IAJLEBKO_00360 2.12e-77 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
IAJLEBKO_00361 9.34e-144 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
IAJLEBKO_00362 8.55e-142 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
IAJLEBKO_00363 3.15e-51 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
IAJLEBKO_00364 5.74e-168 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
IAJLEBKO_00365 1.03e-241 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IAJLEBKO_00366 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IAJLEBKO_00367 1.79e-246 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
IAJLEBKO_00368 7.73e-201 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
IAJLEBKO_00369 3.35e-247 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
IAJLEBKO_00370 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
IAJLEBKO_00371 2.49e-105 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
IAJLEBKO_00372 3.42e-142 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
IAJLEBKO_00373 2.86e-113 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
IAJLEBKO_00374 3.96e-177 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IAJLEBKO_00375 1.01e-90 ylxL - - - - - - -
IAJLEBKO_00376 1.74e-167 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
IAJLEBKO_00377 9.41e-200 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IAJLEBKO_00378 7.09e-164 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
IAJLEBKO_00379 1.94e-118 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IAJLEBKO_00380 2.22e-186 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IAJLEBKO_00381 3.8e-179 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
IAJLEBKO_00382 2.2e-273 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
IAJLEBKO_00383 1.15e-296 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
IAJLEBKO_00384 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IAJLEBKO_00385 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IAJLEBKO_00386 9.4e-105 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
IAJLEBKO_00387 4.04e-264 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
IAJLEBKO_00388 6.76e-56 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
IAJLEBKO_00389 6.16e-63 ylxQ - - J - - - ribosomal protein
IAJLEBKO_00390 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IAJLEBKO_00391 3.88e-60 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
IAJLEBKO_00392 1.03e-73 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IAJLEBKO_00393 3.49e-219 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IAJLEBKO_00394 5.25e-232 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
IAJLEBKO_00395 4.12e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IAJLEBKO_00396 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
IAJLEBKO_00397 1.19e-231 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
IAJLEBKO_00398 2.41e-298 mlpA - - S - - - Belongs to the peptidase M16 family
IAJLEBKO_00399 2.17e-56 ymxH - - S - - - YlmC YmxH family
IAJLEBKO_00400 1.91e-205 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
IAJLEBKO_00401 4.75e-138 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
IAJLEBKO_00402 3.92e-246 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IAJLEBKO_00403 2.83e-282 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
IAJLEBKO_00404 7.2e-202 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IAJLEBKO_00405 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IAJLEBKO_00406 1.86e-165 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
IAJLEBKO_00407 6.32e-42 - - - S - - - YlzJ-like protein
IAJLEBKO_00408 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
IAJLEBKO_00409 2.59e-171 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
IAJLEBKO_00410 7.1e-293 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
IAJLEBKO_00411 9.88e-100 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
IAJLEBKO_00412 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
IAJLEBKO_00413 5.12e-303 albE - - S - - - Peptidase M16
IAJLEBKO_00414 3.77e-306 ymfH - - S - - - zinc protease
IAJLEBKO_00415 4.1e-164 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
IAJLEBKO_00416 6.23e-56 ymfJ - - S - - - Protein of unknown function (DUF3243)
IAJLEBKO_00417 3.14e-183 ymfK - - S - - - Protein of unknown function (DUF3388)
IAJLEBKO_00418 4.2e-176 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
IAJLEBKO_00419 1.36e-131 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IAJLEBKO_00420 1.89e-293 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
IAJLEBKO_00421 3.06e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IAJLEBKO_00422 2.22e-278 pbpX - - V - - - Beta-lactamase
IAJLEBKO_00423 2.91e-308 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
IAJLEBKO_00424 3.72e-196 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
IAJLEBKO_00425 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
IAJLEBKO_00426 3.94e-249 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
IAJLEBKO_00427 1.43e-273 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
IAJLEBKO_00428 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IAJLEBKO_00429 2.11e-88 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
IAJLEBKO_00430 7.09e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
IAJLEBKO_00431 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IAJLEBKO_00432 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IAJLEBKO_00434 4.05e-166 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
IAJLEBKO_00435 2.25e-205 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
IAJLEBKO_00436 2.6e-233 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
IAJLEBKO_00437 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
IAJLEBKO_00438 1.46e-46 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
IAJLEBKO_00439 4.95e-307 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
IAJLEBKO_00440 1.76e-186 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
IAJLEBKO_00441 3.42e-180 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
IAJLEBKO_00442 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
IAJLEBKO_00443 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IAJLEBKO_00444 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IAJLEBKO_00445 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
IAJLEBKO_00446 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
IAJLEBKO_00447 1.54e-290 cypA 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
IAJLEBKO_00448 1.74e-101 nucB - - M - - - Deoxyribonuclease NucA/NucB
IAJLEBKO_00449 1.23e-151 yoaK - - S - - - Membrane
IAJLEBKO_00450 3.25e-81 ymzB - - - - - - -
IAJLEBKO_00451 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
IAJLEBKO_00452 2.68e-161 ymaC - - S - - - Replication protein
IAJLEBKO_00453 3.46e-104 ymaD - - O - - - redox protein, regulator of disulfide bond formation
IAJLEBKO_00454 3.04e-71 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
IAJLEBKO_00455 1.5e-62 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
IAJLEBKO_00457 8.12e-75 ymaF - - S - - - YmaF family
IAJLEBKO_00458 8.91e-220 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IAJLEBKO_00459 9e-46 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
IAJLEBKO_00460 1.94e-55 - - - - - - - -
IAJLEBKO_00461 9.42e-29 ymzA - - - - - - -
IAJLEBKO_00462 9.34e-88 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
IAJLEBKO_00463 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IAJLEBKO_00464 6.19e-239 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IAJLEBKO_00465 7.48e-140 ymaB - - S - - - MutT family
IAJLEBKO_00466 6.99e-149 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
IAJLEBKO_00467 1.55e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
IAJLEBKO_00468 2.7e-295 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IAJLEBKO_00469 4.1e-311 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
IAJLEBKO_00470 5.34e-89 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
IAJLEBKO_00471 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
IAJLEBKO_00472 2.3e-32 - - - - - - - -
IAJLEBKO_00473 2.03e-121 - - - - - - - -
IAJLEBKO_00477 4.94e-54 - - - S - - - Protein of unknown function (DUF2568)
IAJLEBKO_00478 2.61e-11 - - - T - - - Histidine kinase
IAJLEBKO_00479 3.42e-09 - - - D - - - nuclear chromosome segregation
IAJLEBKO_00480 2.33e-263 mrjp - - G - - - Major royal jelly protein
IAJLEBKO_00481 8.98e-316 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
IAJLEBKO_00482 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
IAJLEBKO_00483 1.54e-269 xylR - - GK - - - ROK family
IAJLEBKO_00484 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
IAJLEBKO_00485 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
IAJLEBKO_00486 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
IAJLEBKO_00491 1.45e-23 - - - - - - - -
IAJLEBKO_00492 4.59e-155 yobV - - K - - - WYL domain
IAJLEBKO_00493 6.73e-87 dinB - - S - - - DinB family
IAJLEBKO_00494 1.15e-234 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
IAJLEBKO_00497 7.18e-184 yoaP - - K - - - YoaP-like
IAJLEBKO_00498 3.28e-128 - - - J - - - Acetyltransferase (GNAT) domain
IAJLEBKO_00499 7.6e-150 - - - S - - - Domain of unknown function (DUF3885)
IAJLEBKO_00500 4.65e-255 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAJLEBKO_00501 1.65e-152 - - AA10,CBM73 S ko:K03933 - ko00000 Pfam:Chitin_bind_3
IAJLEBKO_00502 9.28e-07 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
IAJLEBKO_00504 1.06e-123 yvgO - - - - - - -
IAJLEBKO_00506 0.0 yobO - - M - - - Pectate lyase superfamily protein
IAJLEBKO_00507 1.74e-101 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
IAJLEBKO_00508 1.79e-178 yndL - - S - - - Replication protein
IAJLEBKO_00509 8.63e-12 - - - - - - - -
IAJLEBKO_00510 4.43e-185 - - - O - - - COG0330 Membrane protease subunits, stomatin prohibitin homologs
IAJLEBKO_00511 7.53e-94 yndM - - S - - - Protein of unknown function (DUF2512)
IAJLEBKO_00513 3.18e-141 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IAJLEBKO_00514 1.01e-67 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
IAJLEBKO_00515 5.22e-145 yneB - - L - - - resolvase
IAJLEBKO_00516 2.33e-43 ynzC - - S - - - UPF0291 protein
IAJLEBKO_00517 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IAJLEBKO_00518 5.14e-105 yneE - - S - - - Sporulation inhibitor of replication protein sirA
IAJLEBKO_00519 6.2e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
IAJLEBKO_00520 1.97e-33 ynzD - - S - - - Spo0E like sporulation regulatory protein
IAJLEBKO_00521 4.47e-164 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
IAJLEBKO_00522 1.43e-75 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
IAJLEBKO_00523 7.59e-97 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
IAJLEBKO_00524 1.97e-97 yneK - - S - - - Protein of unknown function (DUF2621)
IAJLEBKO_00525 2.44e-82 cotM - - O ko:K06335 - ko00000 Spore coat protein
IAJLEBKO_00526 1.97e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
IAJLEBKO_00527 6.2e-22 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
IAJLEBKO_00528 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IAJLEBKO_00529 3.46e-120 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IAJLEBKO_00531 1e-43 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
IAJLEBKO_00532 2.94e-97 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
IAJLEBKO_00533 3.18e-69 yneQ - - - - - - -
IAJLEBKO_00534 3.13e-65 yneR - - S - - - Belongs to the HesB IscA family
IAJLEBKO_00535 7.46e-120 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IAJLEBKO_00536 9.94e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
IAJLEBKO_00537 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IAJLEBKO_00538 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IAJLEBKO_00539 3.14e-19 - - - - - - - -
IAJLEBKO_00540 1.82e-63 ynfC - - - - - - -
IAJLEBKO_00541 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
IAJLEBKO_00542 1.29e-230 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
IAJLEBKO_00543 8.49e-242 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
IAJLEBKO_00544 1.51e-146 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
IAJLEBKO_00545 1.8e-267 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
IAJLEBKO_00546 6.56e-188 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
IAJLEBKO_00547 1.96e-228 regR - - K ko:K02525 - ko00000,ko03000 transcriptional
IAJLEBKO_00548 1.98e-280 exuT - - G ko:K08191,ko:K08194 - ko00000,ko02000 Sugar (and other) transporter
IAJLEBKO_00549 6.68e-198 yndG - - S - - - DoxX-like family
IAJLEBKO_00550 2.35e-101 - - - S - - - Domain of unknown function (DUF4166)
IAJLEBKO_00551 0.0 yndJ - - S - - - YndJ-like protein
IAJLEBKO_00552 1.36e-73 - - - S - - - Platelet-activating factor acetylhydrolase, isoform II
IAJLEBKO_00553 5.59e-97 - - - S - - - Platelet-activating factor acetylhydrolase, isoform II
IAJLEBKO_00554 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
IAJLEBKO_00555 2.03e-67 yvlA - - S - - - Domain of unknown function (DUF4870)
IAJLEBKO_00556 1.04e-306 - - - T - - - Histidine kinase
IAJLEBKO_00557 8.54e-161 - - - T - - - Transcriptional regulatory protein, C terminal
IAJLEBKO_00558 2.95e-316 ynfF 3.2.1.136 GH5 G ko:K15924 - ko00000,ko01000 Glycosyl hydrolase family 30 beta sandwich domain
IAJLEBKO_00559 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
IAJLEBKO_00560 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IAJLEBKO_00561 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IAJLEBKO_00562 0.0 nrsA - - Q ko:K15661 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IAJLEBKO_00563 9.43e-279 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
IAJLEBKO_00564 3.23e-175 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
IAJLEBKO_00565 4.5e-157 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
IAJLEBKO_00566 2.56e-161 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IAJLEBKO_00567 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
IAJLEBKO_00568 6.35e-276 bioI 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
IAJLEBKO_00569 3.22e-246 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IAJLEBKO_00570 4.14e-164 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IAJLEBKO_00571 4.42e-270 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
IAJLEBKO_00572 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
IAJLEBKO_00573 5.24e-183 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
IAJLEBKO_00574 7e-90 yngA - - S - - - membrane
IAJLEBKO_00575 4.67e-202 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
IAJLEBKO_00576 5.33e-135 yngC - - S - - - SNARE associated Golgi protein
IAJLEBKO_00577 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
IAJLEBKO_00578 3.01e-179 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
IAJLEBKO_00579 1.36e-211 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
IAJLEBKO_00580 2.77e-41 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
IAJLEBKO_00581 0.0 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
IAJLEBKO_00582 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
IAJLEBKO_00583 1.08e-267 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
IAJLEBKO_00584 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
IAJLEBKO_00585 1.38e-84 yngL - - S - - - Protein of unknown function (DUF1360)
IAJLEBKO_00586 0.0 - - - Q ko:K15656,ko:K15668 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 D-alanine [D-alanyl carrier protein] ligase activity
IAJLEBKO_00587 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IAJLEBKO_00588 3.96e-54 - - - L - - - transposase activity
IAJLEBKO_00589 1.04e-55 - - - S - - - MazG-like family
IAJLEBKO_00590 1.98e-309 - - - L ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
IAJLEBKO_00591 7.92e-188 - - - L - - - AAA domain
IAJLEBKO_00592 9.96e-167 - - - L - - - AAA domain
IAJLEBKO_00593 3.6e-41 - - - L - - - AAA domain
IAJLEBKO_00594 3.53e-231 - - - S - - - Fusaric acid resistance protein-like
IAJLEBKO_00595 1.7e-236 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IAJLEBKO_00596 9.4e-113 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
IAJLEBKO_00597 0.0 - - - C - - - COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
IAJLEBKO_00598 7.45e-195 - - - C - - - COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
IAJLEBKO_00599 2.85e-109 pucE 1.2.5.3 - C ko:K03518 - ko00000,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
IAJLEBKO_00600 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
IAJLEBKO_00601 4.32e-313 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
IAJLEBKO_00602 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
IAJLEBKO_00603 1.61e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
IAJLEBKO_00604 5.02e-158 - - - E - - - Ring-cleavage extradiol dioxygenase
IAJLEBKO_00605 7.8e-97 yxaI - - S - - - membrane protein domain
IAJLEBKO_00606 3.64e-254 - - - EGP - - - Major Facilitator Superfamily
IAJLEBKO_00607 9.97e-67 arsR3 - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
IAJLEBKO_00608 1.02e-84 - - - S - - - Family of unknown function (DUF5391)
IAJLEBKO_00609 1.45e-190 yxaL - - S - - - PQQ-like domain
IAJLEBKO_00610 9.34e-317 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
IAJLEBKO_00611 1.22e-271 yxbF - - K - - - Bacterial regulatory proteins, tetR family
IAJLEBKO_00612 1.38e-252 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
IAJLEBKO_00613 4.8e-254 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IAJLEBKO_00614 1.07e-131 desR - - T ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IAJLEBKO_00615 2.92e-193 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
IAJLEBKO_00617 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
IAJLEBKO_00618 6.38e-313 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IAJLEBKO_00619 3.94e-221 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
IAJLEBKO_00620 1.75e-174 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
IAJLEBKO_00621 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IAJLEBKO_00622 1.15e-198 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
IAJLEBKO_00623 3.82e-229 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
IAJLEBKO_00624 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
IAJLEBKO_00625 3.12e-221 iolE 4.2.1.44 - H ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
IAJLEBKO_00626 5.22e-294 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
IAJLEBKO_00627 4.97e-248 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
IAJLEBKO_00628 6.24e-212 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
IAJLEBKO_00629 6.94e-200 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
IAJLEBKO_00630 5.25e-200 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
IAJLEBKO_00631 9.37e-159 yxdJ - - T ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IAJLEBKO_00632 6.53e-223 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IAJLEBKO_00633 1.89e-181 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
IAJLEBKO_00634 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
IAJLEBKO_00635 4.9e-76 yxeA - - S - - - Protein of unknown function (DUF1093)
IAJLEBKO_00636 1.75e-229 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
IAJLEBKO_00637 6.55e-45 - - - - - - - -
IAJLEBKO_00638 5.09e-35 yxeD - - - - - - -
IAJLEBKO_00639 3.81e-33 yxeE - - - - - - -
IAJLEBKO_00642 5.46e-192 yxeH - - S - - - hydrolases of the HAD superfamily
IAJLEBKO_00643 8.24e-220 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
IAJLEBKO_00644 4.09e-145 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IAJLEBKO_00645 4.04e-265 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IAJLEBKO_00646 4.49e-296 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
IAJLEBKO_00647 0.0 hutM - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
IAJLEBKO_00648 2.78e-224 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
IAJLEBKO_00649 7.16e-296 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
IAJLEBKO_00650 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IAJLEBKO_00651 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
IAJLEBKO_00652 2.45e-103 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
IAJLEBKO_00653 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
IAJLEBKO_00654 2.39e-85 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
IAJLEBKO_00655 0.0 - - - L - - - HKD family nuclease
IAJLEBKO_00656 8.5e-95 yxiE - - T - - - Belongs to the universal stress protein A family
IAJLEBKO_00657 1.46e-208 yxxF - - EG - - - EamA-like transporter family
IAJLEBKO_00658 6.09e-254 pelB 4.2.2.10, 4.2.2.2 - G ko:K01728,ko:K01732 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
IAJLEBKO_00659 0.0 wapA - - M - - - COG3209 Rhs family protein
IAJLEBKO_00660 4.13e-148 - - - - - - - -
IAJLEBKO_00661 2.51e-109 - - - S - - - Protein of unknown function (DUF4240)
IAJLEBKO_00663 1.3e-81 yxxG - - - - - - -
IAJLEBKO_00664 2.09e-91 yxiG - - - - - - -
IAJLEBKO_00668 2.73e-100 - - - - - - - -
IAJLEBKO_00670 2.28e-12 yxiJ - - S - - - YxiJ-like protein
IAJLEBKO_00671 4.79e-27 - - - - - - - -
IAJLEBKO_00672 8.09e-63 yxiI - - S - - - Protein of unknown function (DUF2716)
IAJLEBKO_00673 4.09e-80 - - - S - - - SMI1-KNR4 cell-wall
IAJLEBKO_00676 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
IAJLEBKO_00677 4.76e-278 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
IAJLEBKO_00678 3.1e-27 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
IAJLEBKO_00679 8.48e-137 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
IAJLEBKO_00681 9.11e-182 bglS - - M - - - licheninase activity
IAJLEBKO_00682 1.57e-281 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
IAJLEBKO_00683 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
IAJLEBKO_00684 3.38e-65 yxiS - - - - - - -
IAJLEBKO_00685 9.35e-120 - - - T - - - Domain of unknown function (DUF4163)
IAJLEBKO_00686 5.75e-267 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IAJLEBKO_00687 9.82e-202 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
IAJLEBKO_00688 4.45e-275 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
IAJLEBKO_00689 1.75e-110 yxjI - - S - - - LURP-one-related
IAJLEBKO_00692 5.46e-299 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
IAJLEBKO_00693 1.04e-246 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
IAJLEBKO_00694 2.68e-120 yxkC - - S - - - Domain of unknown function (DUF4352)
IAJLEBKO_00695 3.28e-189 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
IAJLEBKO_00696 2.25e-209 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
IAJLEBKO_00697 1.06e-260 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IAJLEBKO_00698 2.71e-197 yxkH - - G - - - Polysaccharide deacetylase
IAJLEBKO_00699 5.53e-288 cimH - - C - - - COG3493 Na citrate symporter
IAJLEBKO_00700 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
IAJLEBKO_00701 3.07e-239 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
IAJLEBKO_00702 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
IAJLEBKO_00703 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
IAJLEBKO_00704 5.94e-199 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IAJLEBKO_00705 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
IAJLEBKO_00706 1.59e-245 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
IAJLEBKO_00707 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
IAJLEBKO_00708 1.07e-266 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
IAJLEBKO_00709 5.28e-237 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
IAJLEBKO_00710 2.85e-210 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
IAJLEBKO_00711 0.0 ydhP 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
IAJLEBKO_00712 1.41e-302 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IAJLEBKO_00713 1.53e-63 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IAJLEBKO_00714 2.78e-65 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IAJLEBKO_00715 1.48e-289 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IAJLEBKO_00716 7.5e-76 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
IAJLEBKO_00717 5.34e-213 cbrA3 - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
IAJLEBKO_00718 1.38e-230 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAJLEBKO_00719 3.3e-220 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAJLEBKO_00720 4.59e-145 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
IAJLEBKO_00721 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
IAJLEBKO_00722 4.46e-66 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
IAJLEBKO_00723 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IAJLEBKO_00724 1.18e-67 licA 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IAJLEBKO_00725 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
IAJLEBKO_00726 9.09e-260 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
IAJLEBKO_00727 5.13e-288 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IAJLEBKO_00728 1.96e-49 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IAJLEBKO_00729 2.56e-293 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
IAJLEBKO_00730 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IAJLEBKO_00731 7.08e-18 - - - S - - - D-Ala-teichoic acid biosynthesis protein
IAJLEBKO_00732 7.57e-215 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
IAJLEBKO_00733 2.16e-150 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
IAJLEBKO_00734 1.42e-205 gspA - - M - - - General stress
IAJLEBKO_00735 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
IAJLEBKO_00736 1.34e-314 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IAJLEBKO_00737 1.51e-87 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
IAJLEBKO_00738 1.03e-284 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
IAJLEBKO_00739 8.64e-176 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
IAJLEBKO_00740 9.1e-38 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
IAJLEBKO_00741 7.55e-143 ywbG - - M - - - effector of murein hydrolase
IAJLEBKO_00742 3.67e-75 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
IAJLEBKO_00743 4.83e-202 ywbI - - K - - - Transcriptional regulator
IAJLEBKO_00744 3.2e-176 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IAJLEBKO_00745 3.35e-145 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
IAJLEBKO_00746 1.54e-309 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
IAJLEBKO_00747 1.21e-142 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
IAJLEBKO_00748 3.31e-170 - - - S - - - Streptomycin biosynthesis protein StrF
IAJLEBKO_00749 5.92e-165 - - - H - - - Methionine biosynthesis protein MetW
IAJLEBKO_00751 5.07e-143 - - - K - - - Bacterial regulatory proteins, tetR family
IAJLEBKO_00752 4.03e-80 gtcA - - S - - - GtrA-like protein
IAJLEBKO_00753 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
IAJLEBKO_00754 5.74e-48 ydaS - - S - - - membrane
IAJLEBKO_00755 3.67e-227 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
IAJLEBKO_00756 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IAJLEBKO_00757 4.91e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
IAJLEBKO_00758 1.31e-81 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
IAJLEBKO_00759 2.54e-51 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
IAJLEBKO_00760 7.5e-100 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
IAJLEBKO_00761 1.58e-263 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
IAJLEBKO_00762 4.47e-176 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
IAJLEBKO_00763 2.71e-235 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAJLEBKO_00764 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
IAJLEBKO_00766 1.91e-195 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
IAJLEBKO_00767 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IAJLEBKO_00768 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
IAJLEBKO_00769 5e-26 ywdA - - - - - - -
IAJLEBKO_00770 4.13e-187 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
IAJLEBKO_00771 1.6e-75 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
IAJLEBKO_00772 1.41e-115 ywdD - - - - - - -
IAJLEBKO_00774 3.69e-189 ywdF - - S - - - Glycosyltransferase like family 2
IAJLEBKO_00775 8.43e-170 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IAJLEBKO_00776 1.57e-62 ywdI - - S - - - Family of unknown function (DUF5327)
IAJLEBKO_00777 1.26e-289 ywdJ - - F - - - Xanthine uracil
IAJLEBKO_00778 2.17e-76 ywdK - - S - - - small membrane protein
IAJLEBKO_00779 5.09e-85 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
IAJLEBKO_00780 7.44e-183 spsA - - M - - - Spore Coat
IAJLEBKO_00781 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
IAJLEBKO_00782 1.39e-279 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
IAJLEBKO_00783 1.02e-200 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
IAJLEBKO_00784 8.27e-273 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
IAJLEBKO_00785 1.68e-170 spsF - - M ko:K07257 - ko00000 Spore Coat
IAJLEBKO_00786 1.22e-227 spsG - - M - - - Spore Coat
IAJLEBKO_00787 3.99e-177 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IAJLEBKO_00788 1.51e-232 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IAJLEBKO_00789 2.25e-206 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IAJLEBKO_00790 1.15e-112 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
IAJLEBKO_00791 1.82e-76 - - - - - - - -
IAJLEBKO_00792 3.15e-314 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
IAJLEBKO_00793 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
IAJLEBKO_00794 0.0 rocB - - E - - - arginine degradation protein
IAJLEBKO_00795 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
IAJLEBKO_00796 4.68e-263 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
IAJLEBKO_00797 4.53e-283 ywfA - - EGP - - - -transporter
IAJLEBKO_00798 1.4e-146 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
IAJLEBKO_00799 1.19e-176 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
IAJLEBKO_00800 1.56e-178 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IAJLEBKO_00801 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
IAJLEBKO_00802 1.16e-264 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
IAJLEBKO_00803 2.21e-297 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
IAJLEBKO_00804 1.7e-180 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
IAJLEBKO_00805 4.87e-187 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
IAJLEBKO_00806 2.03e-225 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
IAJLEBKO_00807 3.42e-213 - - - S - - - Conserved hypothetical protein 698
IAJLEBKO_00808 3.89e-211 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
IAJLEBKO_00809 2.81e-198 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
IAJLEBKO_00811 3.07e-224 - - - - - - - -
IAJLEBKO_00814 1.4e-213 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC transporter (permease)
IAJLEBKO_00815 2.61e-208 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IAJLEBKO_00816 4.41e-119 - - - S - - - membrane
IAJLEBKO_00817 9.26e-69 - - - K ko:K10947 - ko00000,ko03000 PadR family transcriptional regulator
IAJLEBKO_00818 7.1e-145 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
IAJLEBKO_00819 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
IAJLEBKO_00820 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
IAJLEBKO_00821 8.24e-115 ywgA - - - ko:K09388 - ko00000 -
IAJLEBKO_00822 1.91e-313 potE5 - - E ko:K03294 - ko00000 C-terminus of AA_permease
IAJLEBKO_00823 9.43e-90 ywhA - - K - - - Transcriptional regulator
IAJLEBKO_00824 2.37e-34 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
IAJLEBKO_00825 3.84e-153 ywhC - - S - - - Peptidase family M50
IAJLEBKO_00826 2.16e-120 ywhD - - S - - - YwhD family
IAJLEBKO_00827 2.9e-104 - - - - - - - -
IAJLEBKO_00828 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
IAJLEBKO_00829 1.58e-203 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IAJLEBKO_00830 4.95e-214 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
IAJLEBKO_00833 1.15e-98 - - - CP - - - Membrane
IAJLEBKO_00835 9.48e-43 - - - - - - - -
IAJLEBKO_00836 7.54e-40 ydcG - - K ko:K07729 - ko00000,ko03000 sequence-specific DNA binding
IAJLEBKO_00838 2.01e-89 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
IAJLEBKO_00839 4.79e-57 ywiB - - S - - - protein conserved in bacteria
IAJLEBKO_00840 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
IAJLEBKO_00841 1.66e-270 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
IAJLEBKO_00842 2.21e-166 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
IAJLEBKO_00843 6.16e-178 ywiC - - S - - - YwiC-like protein
IAJLEBKO_00844 1.38e-107 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
IAJLEBKO_00845 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IAJLEBKO_00846 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
IAJLEBKO_00847 8.57e-122 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
IAJLEBKO_00848 1.56e-154 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
IAJLEBKO_00849 2.89e-134 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
IAJLEBKO_00850 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IAJLEBKO_00851 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
IAJLEBKO_00852 1.13e-58 ywjC - - - - - - -
IAJLEBKO_00853 3.16e-232 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
IAJLEBKO_00854 2.84e-284 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
IAJLEBKO_00855 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
IAJLEBKO_00856 3.24e-73 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IAJLEBKO_00857 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IAJLEBKO_00858 7.8e-119 ywjG - - S - - - Domain of unknown function (DUF2529)
IAJLEBKO_00859 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
IAJLEBKO_00860 5.51e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
IAJLEBKO_00861 6.37e-144 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IAJLEBKO_00862 3.21e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IAJLEBKO_00863 1.43e-224 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
IAJLEBKO_00864 5.13e-304 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IAJLEBKO_00865 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
IAJLEBKO_00866 4.76e-133 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
IAJLEBKO_00867 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
IAJLEBKO_00868 1.93e-200 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
IAJLEBKO_00869 2.86e-121 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
IAJLEBKO_00870 1.51e-87 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IAJLEBKO_00871 1.11e-244 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IAJLEBKO_00872 1.29e-198 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IAJLEBKO_00874 2.08e-79 ywlA - - S - - - Uncharacterised protein family (UPF0715)
IAJLEBKO_00875 1.88e-152 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
IAJLEBKO_00876 7.03e-98 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
IAJLEBKO_00877 6.22e-243 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IAJLEBKO_00878 3.91e-118 mntP - - P - - - Probably functions as a manganese efflux pump
IAJLEBKO_00879 1.2e-100 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IAJLEBKO_00880 6.74e-106 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
IAJLEBKO_00881 7.42e-125 ywlG - - S - - - Belongs to the UPF0340 family
IAJLEBKO_00882 5.69e-299 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IAJLEBKO_00883 2.24e-147 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IAJLEBKO_00884 4.49e-80 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
IAJLEBKO_00885 5.19e-168 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
IAJLEBKO_00886 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IAJLEBKO_00887 1.66e-82 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IAJLEBKO_00888 1.95e-116 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IAJLEBKO_00889 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IAJLEBKO_00890 1.1e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IAJLEBKO_00891 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IAJLEBKO_00892 8.24e-83 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
IAJLEBKO_00893 6.9e-116 ywmA - - - - - - -
IAJLEBKO_00894 5.31e-44 ywzB - - S - - - membrane
IAJLEBKO_00895 3.4e-174 ywmB - - S - - - TATA-box binding
IAJLEBKO_00896 4.75e-304 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IAJLEBKO_00897 6.71e-241 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
IAJLEBKO_00898 1.36e-146 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
IAJLEBKO_00899 1.75e-157 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
IAJLEBKO_00901 4.3e-185 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IAJLEBKO_00902 2.18e-245 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IAJLEBKO_00903 6.28e-116 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
IAJLEBKO_00904 5e-106 ywmF - - S - - - Peptidase M50
IAJLEBKO_00905 7.2e-18 csbD - - K - - - CsbD-like
IAJLEBKO_00906 1.94e-66 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
IAJLEBKO_00907 8.83e-81 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
IAJLEBKO_00908 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
IAJLEBKO_00909 3.09e-88 ywnA - - K - - - Transcriptional regulator
IAJLEBKO_00910 1.52e-156 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
IAJLEBKO_00911 1.1e-76 ywnC - - S - - - Family of unknown function (DUF5362)
IAJLEBKO_00912 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IAJLEBKO_00913 5.15e-90 ywnF - - S - - - Family of unknown function (DUF5392)
IAJLEBKO_00915 2.76e-115 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
IAJLEBKO_00916 3.6e-186 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
IAJLEBKO_00917 5.45e-94 ywnJ - - S - - - VanZ like family
IAJLEBKO_00918 4.76e-131 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
IAJLEBKO_00919 9.52e-264 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
IAJLEBKO_00920 1.29e-76 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
IAJLEBKO_00921 1.32e-291 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
IAJLEBKO_00922 1.13e-132 yjgF - - Q - - - Isochorismatase family
IAJLEBKO_00923 8.05e-312 ywoD - - EGP - - - Major facilitator superfamily
IAJLEBKO_00924 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
IAJLEBKO_00925 4.78e-271 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
IAJLEBKO_00926 1.46e-92 ywoH - - K - - - transcriptional
IAJLEBKO_00927 5.93e-60 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
IAJLEBKO_00928 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
IAJLEBKO_00929 2.09e-173 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
IAJLEBKO_00930 4.27e-184 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
IAJLEBKO_00931 3.02e-254 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
IAJLEBKO_00932 3.15e-98 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IAJLEBKO_00933 1.87e-74 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IAJLEBKO_00934 1.07e-89 ywpF - - S - - - YwpF-like protein
IAJLEBKO_00935 4.49e-82 ywpG - - - - - - -
IAJLEBKO_00936 1.47e-76 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
IAJLEBKO_00937 1.18e-181 glcR - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
IAJLEBKO_00938 7.2e-200 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
IAJLEBKO_00939 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
IAJLEBKO_00940 0.0 ywqB - - S - - - SWIM zinc finger
IAJLEBKO_00941 1.74e-21 - - - - - - - -
IAJLEBKO_00942 1.95e-149 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
IAJLEBKO_00943 2.12e-155 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
IAJLEBKO_00944 2.05e-179 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
IAJLEBKO_00945 6.86e-311 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IAJLEBKO_00946 1.26e-93 ywqG - - S - - - Domain of unknown function (DUF1963)
IAJLEBKO_00947 4e-201 - - - K - - - Transcriptional regulator
IAJLEBKO_00948 6.32e-122 ywqN - - S - - - NAD(P)H-dependent
IAJLEBKO_00950 7.09e-113 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
IAJLEBKO_00951 2.84e-130 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
IAJLEBKO_00952 1.01e-109 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
IAJLEBKO_00953 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
IAJLEBKO_00955 5.72e-144 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IAJLEBKO_00956 3.39e-25 - - - - - - - -
IAJLEBKO_00957 5.34e-269 cotH - - M ko:K06330 - ko00000 Spore Coat
IAJLEBKO_00958 6.63e-172 cotB - - - ko:K06325 - ko00000 -
IAJLEBKO_00959 1.63e-161 ywrJ - - - - - - -
IAJLEBKO_00960 4.73e-301 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IAJLEBKO_00962 2.18e-214 alsR - - K - - - LysR substrate binding domain
IAJLEBKO_00963 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
IAJLEBKO_00964 5.71e-191 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
IAJLEBKO_00965 7.13e-123 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
IAJLEBKO_00966 1.44e-116 batE - - T - - - Sh3 type 3 domain protein
IAJLEBKO_00967 2.32e-206 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
IAJLEBKO_00968 5.37e-205 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
IAJLEBKO_00969 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
IAJLEBKO_00970 7.65e-83 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
IAJLEBKO_00971 1.56e-198 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IAJLEBKO_00972 4.99e-227 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
IAJLEBKO_00973 3.56e-260 gerKC - - S - - - Spore germination B3/ GerAC like, C-terminal
IAJLEBKO_00974 5.98e-245 - - - E - - - Spore germination protein
IAJLEBKO_00975 8.08e-245 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
IAJLEBKO_00976 3.44e-282 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
IAJLEBKO_00977 2.95e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
IAJLEBKO_00978 2.7e-278 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
IAJLEBKO_00979 4.04e-29 ywtC - - - - - - -
IAJLEBKO_00980 6.9e-298 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
IAJLEBKO_00981 1.11e-72 yttA - - S - - - Pfam Transposase IS66
IAJLEBKO_00982 1.77e-200 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
IAJLEBKO_00983 2.3e-229 ywtF_2 - - K - - - Transcriptional regulator
IAJLEBKO_00984 8.17e-316 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IAJLEBKO_00985 0.0 - - - J ko:K07011 - ko00000 Glycosyl transferase family 2
IAJLEBKO_00986 9.21e-267 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
IAJLEBKO_00987 4.98e-251 gerBB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
IAJLEBKO_00988 0.0 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
IAJLEBKO_00989 5.92e-235 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
IAJLEBKO_00990 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IAJLEBKO_00991 5.87e-276 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IAJLEBKO_00992 8.69e-182 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
IAJLEBKO_00993 2.69e-91 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
IAJLEBKO_00994 0.0 - - - M - - - Glycosyltransferase like family 2
IAJLEBKO_00995 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IAJLEBKO_00996 5.06e-195 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
IAJLEBKO_00997 0.0 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
IAJLEBKO_00998 2.64e-211 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
IAJLEBKO_00999 8.19e-267 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IAJLEBKO_01000 4.48e-204 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
IAJLEBKO_01001 1.86e-64 - - - - - - - -
IAJLEBKO_01002 0.0 lytB - - D - - - Stage II sporulation protein
IAJLEBKO_01003 0.0 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
IAJLEBKO_01004 4.22e-151 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
IAJLEBKO_01005 0.0 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IAJLEBKO_01006 7.54e-284 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
IAJLEBKO_01007 9.32e-317 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IAJLEBKO_01008 0.0 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
IAJLEBKO_01009 3.49e-148 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
IAJLEBKO_01010 2.82e-185 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
IAJLEBKO_01011 5.02e-298 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
IAJLEBKO_01012 3.12e-233 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
IAJLEBKO_01013 2.21e-229 yvhJ - - K - - - Transcriptional regulator
IAJLEBKO_01014 3.43e-154 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
IAJLEBKO_01015 1.4e-246 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
IAJLEBKO_01016 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IAJLEBKO_01017 8.81e-204 degV - - S - - - protein conserved in bacteria
IAJLEBKO_01018 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
IAJLEBKO_01019 3.56e-57 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
IAJLEBKO_01020 6.79e-98 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
IAJLEBKO_01021 2.23e-97 yvyF - - S - - - flagellar protein
IAJLEBKO_01022 6.14e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
IAJLEBKO_01023 2.2e-105 yvyG - - NOU - - - FlgN protein
IAJLEBKO_01024 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
IAJLEBKO_01025 1.4e-207 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
IAJLEBKO_01026 2.8e-108 yviE - - - - - - -
IAJLEBKO_01027 2.48e-96 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
IAJLEBKO_01028 2.67e-43 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IAJLEBKO_01029 4.55e-153 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IAJLEBKO_01030 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IAJLEBKO_01031 5.79e-88 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
IAJLEBKO_01032 3.08e-10 fliT - - N ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
IAJLEBKO_01033 1.35e-89 - - - - - - - -
IAJLEBKO_01034 3.94e-133 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IAJLEBKO_01035 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IAJLEBKO_01036 6.64e-233 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IAJLEBKO_01037 6.56e-190 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
IAJLEBKO_01038 3.08e-60 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
IAJLEBKO_01039 3.53e-158 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
IAJLEBKO_01040 2.89e-197 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
IAJLEBKO_01041 4.04e-303 ywoF - - P - - - Right handed beta helix region
IAJLEBKO_01042 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
IAJLEBKO_01043 4.34e-67 swrA - - S - - - Swarming motility protein
IAJLEBKO_01044 3.57e-281 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IAJLEBKO_01045 1.98e-230 - - - S - - - Psort location CytoplasmicMembrane, score
IAJLEBKO_01047 8.78e-34 - - - Q - - - Thioesterase domain
IAJLEBKO_01048 1.66e-37 - - - L - - - Transposase, Mutator family
IAJLEBKO_01049 9.55e-22 - - - L - - - Transposase, Mutator family
IAJLEBKO_01050 4.48e-09 - - - L - - - Transposase, Mutator family
IAJLEBKO_01051 3.42e-297 yvkA - - P - - - -transporter
IAJLEBKO_01052 7.78e-143 yvkB - - K - - - Transcriptional regulator
IAJLEBKO_01053 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
IAJLEBKO_01054 2.59e-45 csbA - - S - - - protein conserved in bacteria
IAJLEBKO_01055 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IAJLEBKO_01056 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IAJLEBKO_01057 8.07e-44 yvkN - - - - - - -
IAJLEBKO_01058 4.87e-66 yvlA - - - - - - -
IAJLEBKO_01059 9.16e-218 yvlB - - S - - - Putative adhesin
IAJLEBKO_01060 8.1e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
IAJLEBKO_01061 3.12e-65 yvlD - - S ko:K08972 - ko00000 Membrane
IAJLEBKO_01062 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
IAJLEBKO_01063 1.73e-133 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
IAJLEBKO_01064 4.29e-171 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
IAJLEBKO_01065 2.22e-172 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IAJLEBKO_01066 7.52e-283 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
IAJLEBKO_01067 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IAJLEBKO_01068 8.74e-194 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IAJLEBKO_01069 1.35e-156 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
IAJLEBKO_01070 8.08e-109 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
IAJLEBKO_01071 8.4e-177 yvpB - - NU - - - protein conserved in bacteria
IAJLEBKO_01072 2.45e-269 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IAJLEBKO_01073 1.76e-146 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
IAJLEBKO_01074 1.51e-296 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IAJLEBKO_01075 3.35e-137 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
IAJLEBKO_01076 2.32e-146 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IAJLEBKO_01077 9.3e-167 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IAJLEBKO_01078 1.09e-173 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
IAJLEBKO_01079 4.7e-143 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
IAJLEBKO_01080 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
IAJLEBKO_01081 3.3e-61 - - - - - - - -
IAJLEBKO_01082 1.33e-156 mprA3 - - T - - - COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IAJLEBKO_01083 1.85e-243 sasA - - T - - - Histidine kinase
IAJLEBKO_01084 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
IAJLEBKO_01085 3.05e-203 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
IAJLEBKO_01086 3.13e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IAJLEBKO_01087 5.15e-113 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
IAJLEBKO_01088 2.09e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
IAJLEBKO_01089 1.49e-224 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
IAJLEBKO_01090 1.04e-219 whiA - - K ko:K09762 - ko00000 May be required for sporulation
IAJLEBKO_01091 3.23e-49 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
IAJLEBKO_01092 1.99e-183 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
IAJLEBKO_01093 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IAJLEBKO_01094 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IAJLEBKO_01095 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IAJLEBKO_01096 0.0 - 1.6.5.5 - C ko:K00344 - ko00000,ko01000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
IAJLEBKO_01097 1.98e-281 - 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
IAJLEBKO_01098 1.45e-304 - 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
IAJLEBKO_01099 1.38e-174 - - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
IAJLEBKO_01100 8.24e-185 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IAJLEBKO_01101 3.63e-219 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
IAJLEBKO_01102 2.39e-180 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
IAJLEBKO_01103 9.26e-317 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
IAJLEBKO_01104 6.33e-227 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
IAJLEBKO_01105 7.67e-96 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IAJLEBKO_01107 1.18e-237 yueF - - S - - - transporter activity
IAJLEBKO_01109 1.26e-73 - - - S - - - YolD-like protein
IAJLEBKO_01110 7.74e-298 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IAJLEBKO_01111 1.15e-114 yqjY - - K ko:K06977 - ko00000 acetyltransferase
IAJLEBKO_01112 3.46e-80 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
IAJLEBKO_01113 3.26e-220 yqkA - - K - - - GrpB protein
IAJLEBKO_01114 5.4e-80 yqkB - - S - - - Belongs to the HesB IscA family
IAJLEBKO_01115 7.88e-54 yqkC - - S - - - Protein of unknown function (DUF2552)
IAJLEBKO_01116 5.57e-224 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
IAJLEBKO_01117 5.53e-09 yqkE - - S - - - Protein of unknown function (DUF3886)
IAJLEBKO_01118 8.51e-214 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
IAJLEBKO_01119 2.01e-10 - - - S - - - Protein of unknown function (DUF3936)
IAJLEBKO_01120 1.04e-122 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
IAJLEBKO_01121 5.91e-280 yqxK - - L - - - DNA helicase
IAJLEBKO_01122 4e-76 ansR - - K - - - Transcriptional regulator
IAJLEBKO_01123 1.3e-240 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
IAJLEBKO_01124 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
IAJLEBKO_01125 1.19e-311 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
IAJLEBKO_01126 2.38e-309 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
IAJLEBKO_01127 1.96e-30 - - - - - - - -
IAJLEBKO_01128 7.29e-46 yqkK - - - - - - -
IAJLEBKO_01130 1.01e-141 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
IAJLEBKO_01131 4.56e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
IAJLEBKO_01132 9.51e-51 - - - S - - - Protein of unknown function (DUF4227)
IAJLEBKO_01133 1.59e-213 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
IAJLEBKO_01134 2.88e-293 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
IAJLEBKO_01135 2.49e-189 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IAJLEBKO_01136 3.52e-273 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
IAJLEBKO_01137 4e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
IAJLEBKO_01138 4.77e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
IAJLEBKO_01139 6.81e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IAJLEBKO_01140 6.68e-143 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
IAJLEBKO_01141 2.03e-78 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
IAJLEBKO_01142 9.92e-104 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
IAJLEBKO_01143 5.53e-242 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
IAJLEBKO_01144 2.15e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
IAJLEBKO_01145 7.55e-142 - - - S ko:K06407 - ko00000 stage V sporulation protein
IAJLEBKO_01146 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
IAJLEBKO_01147 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IAJLEBKO_01148 3.65e-198 ypuA - - S - - - Secreted protein
IAJLEBKO_01149 4.12e-104 ppiB 5.2.1.8 - O ko:K01802,ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IAJLEBKO_01150 5.79e-107 ccdC1 - - O - - - Protein of unknown function (DUF1453)
IAJLEBKO_01151 8.95e-129 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
IAJLEBKO_01152 2.01e-70 ypuD - - - - - - -
IAJLEBKO_01153 7.27e-266 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IAJLEBKO_01154 3.97e-144 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
IAJLEBKO_01155 1.8e-291 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IAJLEBKO_01156 6.92e-106 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
IAJLEBKO_01157 2.74e-84 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IAJLEBKO_01158 4.02e-121 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
IAJLEBKO_01160 1.65e-163 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IAJLEBKO_01161 7.84e-133 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IAJLEBKO_01162 6.14e-122 ypuI - - S - - - Protein of unknown function (DUF3907)
IAJLEBKO_01163 1.14e-275 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
IAJLEBKO_01164 5.33e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
IAJLEBKO_01165 8.99e-116 spmB - - S ko:K06374 - ko00000 Spore maturation protein
IAJLEBKO_01166 1.49e-167 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
IAJLEBKO_01167 4.31e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
IAJLEBKO_01168 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
IAJLEBKO_01169 6.24e-252 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
IAJLEBKO_01170 9.77e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IAJLEBKO_01171 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IAJLEBKO_01172 3.22e-135 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IAJLEBKO_01173 8.77e-244 rsiX - - - - - - -
IAJLEBKO_01174 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IAJLEBKO_01175 2.16e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IAJLEBKO_01176 5.88e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
IAJLEBKO_01177 3.37e-250 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
IAJLEBKO_01178 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
IAJLEBKO_01179 1.4e-127 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
IAJLEBKO_01180 1.59e-121 ypbE - - M - - - Lysin motif
IAJLEBKO_01181 5.5e-111 ypbF - - S - - - Protein of unknown function (DUF2663)
IAJLEBKO_01182 2.22e-187 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
IAJLEBKO_01183 3.35e-137 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
IAJLEBKO_01184 1.81e-311 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
IAJLEBKO_01185 7.53e-239 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
IAJLEBKO_01186 6.4e-156 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
IAJLEBKO_01187 2.09e-210 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
IAJLEBKO_01188 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
IAJLEBKO_01189 2.7e-76 ypfA - - M - - - Flagellar protein YcgR
IAJLEBKO_01190 7.86e-18 - - - S - - - Family of unknown function (DUF5359)
IAJLEBKO_01191 2.02e-146 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
IAJLEBKO_01192 8.14e-264 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
IAJLEBKO_01193 3.99e-236 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IAJLEBKO_01194 1.87e-12 - - - S - - - YpzI-like protein
IAJLEBKO_01195 8.44e-134 yphA - - - - - - -
IAJLEBKO_01196 0.0 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
IAJLEBKO_01197 4.93e-244 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
IAJLEBKO_01198 3.25e-23 yphE - - S - - - Protein of unknown function (DUF2768)
IAJLEBKO_01199 3.97e-172 yphF - - - - - - -
IAJLEBKO_01200 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
IAJLEBKO_01201 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IAJLEBKO_01202 6.27e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
IAJLEBKO_01203 6.23e-47 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
IAJLEBKO_01204 1.61e-176 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
IAJLEBKO_01205 7.76e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
IAJLEBKO_01206 2.29e-251 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
IAJLEBKO_01207 2.86e-102 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
IAJLEBKO_01208 3.4e-179 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
IAJLEBKO_01209 9.75e-276 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IAJLEBKO_01210 1.06e-258 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IAJLEBKO_01211 2.93e-79 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
IAJLEBKO_01212 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IAJLEBKO_01213 5.32e-208 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IAJLEBKO_01214 2.02e-168 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
IAJLEBKO_01215 1.68e-146 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
IAJLEBKO_01216 5.79e-289 trpB 4.2.1.20 - E ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
IAJLEBKO_01217 2.8e-187 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
IAJLEBKO_01218 1.5e-257 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IAJLEBKO_01219 1.39e-257 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
IAJLEBKO_01220 1.03e-303 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
IAJLEBKO_01221 2.15e-298 ypiA - - S - - - COG0457 FOG TPR repeat
IAJLEBKO_01222 2.6e-129 ypiB - - S - - - Belongs to the UPF0302 family
IAJLEBKO_01223 3.34e-101 ypiF - - S - - - Protein of unknown function (DUF2487)
IAJLEBKO_01224 2.86e-127 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
IAJLEBKO_01225 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
IAJLEBKO_01226 2.33e-190 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
IAJLEBKO_01227 2.17e-135 ypjA - - S - - - membrane
IAJLEBKO_01228 1.96e-180 ypjB - - S - - - sporulation protein
IAJLEBKO_01229 4.06e-289 - 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
IAJLEBKO_01230 4.31e-199 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
IAJLEBKO_01231 2.47e-74 ypjD - - S - - - Nucleotide pyrophosphohydrolase
IAJLEBKO_01232 1.1e-188 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IAJLEBKO_01233 6.19e-94 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
IAJLEBKO_01234 4.48e-170 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
IAJLEBKO_01235 2.55e-269 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
IAJLEBKO_01236 7.21e-281 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IAJLEBKO_01237 5.22e-229 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IAJLEBKO_01238 8.63e-188 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
IAJLEBKO_01239 1.91e-200 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IAJLEBKO_01240 2.41e-84 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
IAJLEBKO_01241 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
IAJLEBKO_01242 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
IAJLEBKO_01243 6.52e-103 ypmB - - S - - - protein conserved in bacteria
IAJLEBKO_01244 5.7e-281 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
IAJLEBKO_01245 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
IAJLEBKO_01246 3.42e-167 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
IAJLEBKO_01247 1.7e-156 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IAJLEBKO_01248 1.04e-118 ypoC - - - - - - -
IAJLEBKO_01249 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
IAJLEBKO_01250 7.27e-145 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IAJLEBKO_01251 2e-239 yppC - - S - - - Protein of unknown function (DUF2515)
IAJLEBKO_01252 0.000542 - - - - ko:K06430 - ko00000 -
IAJLEBKO_01256 9.54e-81 yppG - - S - - - YppG-like protein
IAJLEBKO_01257 7.23e-93 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
IAJLEBKO_01258 9.93e-115 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
IAJLEBKO_01259 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
IAJLEBKO_01260 1.85e-282 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
IAJLEBKO_01262 9.36e-48 cotD - - S ko:K06327 - ko00000 Inner spore coat protein D
IAJLEBKO_01263 5.42e-128 ypsA - - S - - - Belongs to the UPF0398 family
IAJLEBKO_01264 5.52e-61 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IAJLEBKO_01265 1.29e-273 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
IAJLEBKO_01266 6.91e-31 - - - S - - - YpzG-like protein
IAJLEBKO_01268 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
IAJLEBKO_01269 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
IAJLEBKO_01270 8.16e-129 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IAJLEBKO_01271 3.57e-298 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine
IAJLEBKO_01272 3.13e-176 - - - L - - - Belongs to the 'phage' integrase family
IAJLEBKO_01273 1.63e-18 - - - K - - - Helix-turn-helix XRE-family like proteins
IAJLEBKO_01274 6.12e-08 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
IAJLEBKO_01275 1.27e-43 - - - - - - - -
IAJLEBKO_01276 2.33e-91 - - - S - - - DNA binding
IAJLEBKO_01277 1.19e-112 - - - - - - - -
IAJLEBKO_01281 5.31e-126 - - - - - - - -
IAJLEBKO_01282 1.21e-78 pi112 - - L - - - PDDEXK-like domain of unknown function (DUF3799)
IAJLEBKO_01284 5.91e-100 yqaL - - L - - - DnaD domain protein
IAJLEBKO_01285 1.11e-149 yqaM - - L - - - IstB-like ATP binding protein
IAJLEBKO_01287 4.37e-76 rusA - - L - - - Endodeoxyribonuclease RusA
IAJLEBKO_01289 1.85e-29 yqaO - - S - - - Phage-like element PBSX protein XtrA
IAJLEBKO_01291 2.29e-07 - - - - - - - -
IAJLEBKO_01293 3.03e-88 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
IAJLEBKO_01297 2.95e-23 - - - K - - - Transcriptional regulator
IAJLEBKO_01300 4.94e-100 - - - L - - - phage terminase small subunit
IAJLEBKO_01301 0.0 - - - S - - - Terminase
IAJLEBKO_01302 2.47e-216 - - - S - - - Phage portal protein
IAJLEBKO_01303 9.69e-105 - - - S - - - peptidase activity
IAJLEBKO_01304 2.38e-200 - - - S - - - capsid protein
IAJLEBKO_01305 2.8e-34 - - - - - - - -
IAJLEBKO_01306 4.88e-51 - - - S - - - Phage gp6-like head-tail connector protein
IAJLEBKO_01307 6.9e-55 - - - S - - - Phage head-tail joining protein
IAJLEBKO_01308 3.27e-64 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
IAJLEBKO_01310 1.39e-104 - - - S - - - Phage tail tube protein
IAJLEBKO_01311 6.81e-06 - - - - - - - -
IAJLEBKO_01312 0.0 - - - D - - - phage tail tape measure protein
IAJLEBKO_01313 2.92e-129 - - - S - - - Phage tail protein
IAJLEBKO_01314 9.28e-288 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
IAJLEBKO_01315 0.0 - - - S - - - Peptidase_G2, IMC autoproteolytic cleavage domain
IAJLEBKO_01316 2.99e-120 - - - - - - - -
IAJLEBKO_01317 0.000763 - - - - - - - -
IAJLEBKO_01318 4.85e-07 - - - S - - - Phage uncharacterised protein (Phage_XkdX)
IAJLEBKO_01319 6.18e-74 - - - S - - - Pfam:Phage_holin_4_1
IAJLEBKO_01320 1.72e-86 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 Ami_2
IAJLEBKO_01323 1.11e-104 tagE 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
IAJLEBKO_01325 1.94e-37 - - - K - - - Helix-turn-helix domain
IAJLEBKO_01326 5.22e-91 - - - S - - - Protein of unknown function (DUF3800)
IAJLEBKO_01327 4.67e-07 - - - - - - - -
IAJLEBKO_01328 1.04e-128 yrdC - - Q - - - Isochorismatase family
IAJLEBKO_01329 2.73e-42 ydfR - - S - - - Protein of unknown function (DUF421)
IAJLEBKO_01330 1.78e-29 ydfR - - S - - - Protein of unknown function (DUF421)
IAJLEBKO_01331 1.95e-07 - - - S - - - Bacillus cereus group antimicrobial protein
IAJLEBKO_01332 1.17e-65 MGMT - - L ko:K07443 - ko00000 6-O-methylguanine DNA methyltransferase, DNA binding domain
IAJLEBKO_01333 7.21e-136 - - - J - - - Acetyltransferase (GNAT) domain
IAJLEBKO_01334 1.35e-263 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
IAJLEBKO_01335 1.26e-117 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
IAJLEBKO_01336 0.0 ypbR - - S - - - Dynamin family
IAJLEBKO_01337 1.17e-51 ypbS - - S - - - Protein of unknown function (DUF2533)
IAJLEBKO_01338 2.44e-10 - - - - - - - -
IAJLEBKO_01339 3.19e-208 ypcP - - L - - - 5'3' exonuclease
IAJLEBKO_01341 2.47e-88 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
IAJLEBKO_01342 9.33e-153 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IAJLEBKO_01343 8.39e-159 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
IAJLEBKO_01344 6.59e-40 ypeQ - - S - - - Zinc-finger
IAJLEBKO_01345 1.13e-49 - - - S - - - Protein of unknown function (DUF2564)
IAJLEBKO_01346 5.19e-17 degR - - - - - - -
IAJLEBKO_01347 5.12e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
IAJLEBKO_01348 9e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
IAJLEBKO_01349 2.3e-227 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IAJLEBKO_01350 1.08e-110 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
IAJLEBKO_01351 3.97e-129 yagB - - S ko:K06950 - ko00000 phosphohydrolase
IAJLEBKO_01352 3.51e-200 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
IAJLEBKO_01353 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
IAJLEBKO_01354 4.8e-99 yphP - - S - - - Belongs to the UPF0403 family
IAJLEBKO_01355 4.25e-173 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
IAJLEBKO_01356 9.2e-148 ypjP - - S - - - YpjP-like protein
IAJLEBKO_01357 5.11e-203 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IAJLEBKO_01358 1.43e-115 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IAJLEBKO_01359 1.92e-147 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
IAJLEBKO_01360 5.24e-143 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
IAJLEBKO_01361 1.59e-221 yplP - - K - - - Transcriptional regulator
IAJLEBKO_01362 8.57e-309 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IAJLEBKO_01363 5.02e-52 ypmP - - S - - - Protein of unknown function (DUF2535)
IAJLEBKO_01364 5.97e-136 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
IAJLEBKO_01365 1.67e-172 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
IAJLEBKO_01366 6.53e-125 ypmS - - S - - - protein conserved in bacteria
IAJLEBKO_01367 3.35e-89 ypoP - - K - - - transcriptional
IAJLEBKO_01368 1.2e-133 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IAJLEBKO_01369 4.61e-106 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
IAJLEBKO_01370 1.98e-133 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
IAJLEBKO_01371 0.0 yokA - - L - - - Recombinase
IAJLEBKO_01374 2.03e-107 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
IAJLEBKO_01375 1.88e-112 - - - G - - - SMI1-KNR4 cell-wall
IAJLEBKO_01376 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
IAJLEBKO_01377 3.88e-68 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
IAJLEBKO_01378 1.23e-113 yokK - - S - - - SMI1 / KNR4 family
IAJLEBKO_01379 2.68e-39 - - - S - - - Acetyltransferase (GNAT) domain
IAJLEBKO_01383 1.35e-96 - - - S - - - amine dehydrogenase activity
IAJLEBKO_01384 8.57e-63 - - - S - - - amine dehydrogenase activity
IAJLEBKO_01386 9.46e-226 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
IAJLEBKO_01387 8.71e-23 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
IAJLEBKO_01388 1.3e-99 yoqH - - M - - - LysM domain
IAJLEBKO_01392 8.25e-29 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 - L ko:K01971,ko:K10747 ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450 ko00000,ko00001,ko01000,ko03032,ko03400 ATP-dependent DNA ligase
IAJLEBKO_01393 5.37e-101 - - - - - - - -
IAJLEBKO_01399 3.54e-95 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
IAJLEBKO_01400 7.47e-281 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
IAJLEBKO_01401 1.21e-219 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
IAJLEBKO_01402 1.22e-87 cgeA - - - ko:K06319 - ko00000 -
IAJLEBKO_01403 7.84e-61 cgeC - - - ko:K06321 - ko00000 -
IAJLEBKO_01404 1.26e-306 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
IAJLEBKO_01405 3.3e-184 yiiD - - K ko:K06323 - ko00000 acetyltransferase
IAJLEBKO_01407 8.35e-84 - - - L - - - Bacterial transcription activator, effector binding domain
IAJLEBKO_01408 4.63e-310 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IAJLEBKO_01409 9.76e-161 atoD 2.8.3.8, 2.8.3.9 - I ko:K01034 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IAJLEBKO_01410 4.64e-160 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
IAJLEBKO_01411 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
IAJLEBKO_01412 1.71e-204 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
IAJLEBKO_01413 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
IAJLEBKO_01414 2.83e-62 yokU - - S - - - YokU-like protein, putative antitoxin
IAJLEBKO_01415 2.02e-47 yozE - - S - - - Belongs to the UPF0346 family
IAJLEBKO_01416 6.07e-37 - - - E - - - lactoylglutathione lyase activity
IAJLEBKO_01417 1.9e-161 yodN - - - - - - -
IAJLEBKO_01419 9.77e-34 yozD - - S - - - YozD-like protein
IAJLEBKO_01420 1.76e-132 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
IAJLEBKO_01421 1.16e-72 yodL - - S - - - YodL-like
IAJLEBKO_01423 1.05e-161 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
IAJLEBKO_01424 4.49e-192 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
IAJLEBKO_01425 2.5e-32 yodI - - - - - - -
IAJLEBKO_01426 1.02e-164 yodH - - Q - - - Methyltransferase
IAJLEBKO_01427 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
IAJLEBKO_01428 3.53e-169 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
IAJLEBKO_01429 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
IAJLEBKO_01430 0.0 - 3.2.1.45 GH30 M ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 ko00000,ko00001,ko01000 Glycosyl hydrolase family 30 beta sandwich domain
IAJLEBKO_01431 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IAJLEBKO_01432 1.97e-28 - - - S - - - Protein of unknown function (DUF3311)
IAJLEBKO_01433 2.2e-221 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
IAJLEBKO_01434 2.84e-139 yahD - - S ko:K06999 - ko00000 Carboxylesterase
IAJLEBKO_01435 1.35e-138 yodC - - C - - - nitroreductase
IAJLEBKO_01436 2.42e-74 yodB - - K - - - transcriptional
IAJLEBKO_01437 1.86e-90 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
IAJLEBKO_01438 2.13e-88 iolK - - S - - - tautomerase
IAJLEBKO_01440 4.68e-104 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
IAJLEBKO_01441 5.73e-208 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
IAJLEBKO_01442 1.05e-30 - - - - - - - -
IAJLEBKO_01443 3.3e-79 yojF - - S - - - Protein of unknown function (DUF1806)
IAJLEBKO_01444 9.11e-162 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
IAJLEBKO_01445 5.03e-194 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IAJLEBKO_01446 7.01e-303 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
IAJLEBKO_01448 4.69e-144 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IAJLEBKO_01449 1.11e-283 - - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
IAJLEBKO_01450 8.28e-291 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
IAJLEBKO_01451 1.04e-141 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IAJLEBKO_01452 4.2e-209 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
IAJLEBKO_01453 0.0 yojO - - P - - - Von Willebrand factor
IAJLEBKO_01454 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
IAJLEBKO_01455 7.41e-263 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
IAJLEBKO_01456 7.15e-177 - - - S - - - Metallo-beta-lactamase superfamily
IAJLEBKO_01457 7.77e-214 yocS - - S ko:K03453 - ko00000 -transporter
IAJLEBKO_01458 5.92e-298 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
IAJLEBKO_01459 1.59e-210 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
IAJLEBKO_01460 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
IAJLEBKO_01461 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
IAJLEBKO_01462 1.35e-42 yozC - - - - - - -
IAJLEBKO_01464 5.32e-75 yozO - - S - - - Bacterial PH domain
IAJLEBKO_01465 6.36e-50 yocN - - - - - - -
IAJLEBKO_01466 9.63e-60 yozN - - - - - - -
IAJLEBKO_01467 2.29e-116 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
IAJLEBKO_01469 2.71e-13 yocL - - - - - - -
IAJLEBKO_01470 2.23e-79 yocK - - T - - - general stress protein
IAJLEBKO_01472 2.32e-144 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IAJLEBKO_01473 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
IAJLEBKO_01474 2.62e-159 yocH - - M - - - COG1388 FOG LysM repeat
IAJLEBKO_01476 6.44e-239 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
IAJLEBKO_01477 3.78e-122 yocC - - - - - - -
IAJLEBKO_01478 2.38e-179 - - - J - - - Protein required for attachment to host cells
IAJLEBKO_01479 1.33e-117 yozB - - S ko:K08976 - ko00000 membrane
IAJLEBKO_01480 1.19e-157 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
IAJLEBKO_01481 2.58e-71 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
IAJLEBKO_01482 1.57e-118 yobW - - - - - - -
IAJLEBKO_01483 9.42e-173 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
IAJLEBKO_01484 1.92e-119 yobS - - K - - - Transcriptional regulator
IAJLEBKO_01485 1.45e-170 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
IAJLEBKO_01486 2.12e-70 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
IAJLEBKO_01487 7.06e-80 - - - K - - - HxlR-like helix-turn-helix
IAJLEBKO_01488 4.97e-168 ykvO - - IQ - - - Enoyl-(Acyl carrier protein) reductase
IAJLEBKO_01489 1.99e-58 - - - - - - - -
IAJLEBKO_01490 6.1e-124 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
IAJLEBKO_01491 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IAJLEBKO_01492 1.8e-247 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IAJLEBKO_01493 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
IAJLEBKO_01494 4.46e-261 yoaB - - EGP - - - the major facilitator superfamily
IAJLEBKO_01495 7.62e-170 yoxB - - - - - - -
IAJLEBKO_01496 3.16e-52 - - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IAJLEBKO_01497 2.43e-157 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
IAJLEBKO_01498 8.08e-79 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
IAJLEBKO_01499 3.42e-181 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IAJLEBKO_01500 2.31e-258 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IAJLEBKO_01501 6.93e-204 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
IAJLEBKO_01502 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
IAJLEBKO_01503 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
IAJLEBKO_01504 2.22e-233 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
IAJLEBKO_01505 3.54e-197 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
IAJLEBKO_01506 3.18e-07 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IAJLEBKO_01507 3.29e-67 - - - K - - - Helix-turn-helix domain
IAJLEBKO_01508 9.26e-254 - - - EGP ko:K08164 - ko00000,ko02000 -transporter
IAJLEBKO_01509 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
IAJLEBKO_01510 6.69e-47 yoeD - - G - - - Helix-turn-helix domain
IAJLEBKO_01511 3.97e-125 - - - L - - - Integrase
IAJLEBKO_01513 5.86e-122 yoeB - - S - - - IseA DL-endopeptidase inhibitor
IAJLEBKO_01514 1.75e-310 yoeA - - V - - - MATE efflux family protein
IAJLEBKO_01515 1.52e-236 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
IAJLEBKO_01516 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
IAJLEBKO_01533 1.17e-49 - - - C - - - Na+/H+ antiporter family
IAJLEBKO_01534 3.42e-167 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
IAJLEBKO_01535 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IAJLEBKO_01536 0.0 ygaK - - C - - - Berberine and berberine like
IAJLEBKO_01538 1.91e-292 oppA5 - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 PFAM extracellular solute-binding protein family 5
IAJLEBKO_01539 8.51e-188 - - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IAJLEBKO_01540 8.8e-162 - - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAJLEBKO_01541 3.14e-169 oppD3 - - P ko:K02031 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IAJLEBKO_01542 9.42e-168 oppF9 - - E ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IAJLEBKO_01543 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
IAJLEBKO_01544 8.69e-230 - - - S ko:K07045 - ko00000 Amidohydrolase
IAJLEBKO_01545 4.31e-178 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
IAJLEBKO_01546 5.85e-228 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
IAJLEBKO_01547 3.93e-184 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
IAJLEBKO_01548 1.74e-272 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
IAJLEBKO_01549 1.18e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IAJLEBKO_01550 7.46e-106 ygaO - - - - - - -
IAJLEBKO_01551 9.41e-32 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
IAJLEBKO_01553 2.7e-138 yhzB - - S - - - B3/4 domain
IAJLEBKO_01554 1.64e-284 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IAJLEBKO_01555 1.64e-222 yhbB - - S - - - Putative amidase domain
IAJLEBKO_01556 4.84e-112 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IAJLEBKO_01557 1.14e-139 yhbD - - K - - - Protein of unknown function (DUF4004)
IAJLEBKO_01558 3.25e-84 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
IAJLEBKO_01559 3.13e-91 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
IAJLEBKO_01560 1.23e-07 - - - - - - - -
IAJLEBKO_01561 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
IAJLEBKO_01562 5.45e-279 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
IAJLEBKO_01563 4.15e-98 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
IAJLEBKO_01564 1.54e-132 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
IAJLEBKO_01565 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
IAJLEBKO_01566 9.09e-129 wrbA 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
IAJLEBKO_01567 1.41e-72 yhcC - - - - - - -
IAJLEBKO_01568 9.36e-66 - - - - - - - -
IAJLEBKO_01569 1.35e-80 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
IAJLEBKO_01570 2.32e-158 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IAJLEBKO_01571 9.59e-215 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IAJLEBKO_01572 1.29e-208 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IAJLEBKO_01573 7.28e-42 cspB - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
IAJLEBKO_01574 1.09e-185 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
IAJLEBKO_01575 5.01e-235 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
IAJLEBKO_01576 1e-305 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IAJLEBKO_01577 1.96e-77 yhcM - - - - - - -
IAJLEBKO_01578 2.69e-122 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IAJLEBKO_01579 1.68e-206 yhcP - - - - - - -
IAJLEBKO_01580 7.38e-150 yhcQ - - M - - - Spore coat protein
IAJLEBKO_01581 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
IAJLEBKO_01582 2.63e-136 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
IAJLEBKO_01583 1.79e-213 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
IAJLEBKO_01584 1.88e-92 yhcU - - S - - - Family of unknown function (DUF5365)
IAJLEBKO_01585 3.54e-90 yhcV - - S - - - COG0517 FOG CBS domain
IAJLEBKO_01586 1.39e-160 yhcW - - S ko:K07025 - ko00000 hydrolase
IAJLEBKO_01587 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IAJLEBKO_01588 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IAJLEBKO_01589 8.57e-134 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
IAJLEBKO_01590 2.32e-198 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
IAJLEBKO_01591 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IAJLEBKO_01592 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IAJLEBKO_01593 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
IAJLEBKO_01594 1.45e-87 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
IAJLEBKO_01595 9.04e-48 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IAJLEBKO_01596 4.84e-116 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
IAJLEBKO_01597 6.98e-53 yhdB - - S - - - YhdB-like protein
IAJLEBKO_01598 1.46e-71 yhdC - - S - - - Protein of unknown function (DUF3889)
IAJLEBKO_01599 3.32e-294 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
IAJLEBKO_01600 7.66e-96 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
IAJLEBKO_01601 0.0 ygxB - - M - - - Conserved TM helix
IAJLEBKO_01602 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
IAJLEBKO_01603 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
IAJLEBKO_01604 3.98e-171 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
IAJLEBKO_01605 1.16e-208 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
IAJLEBKO_01606 6.67e-261 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
IAJLEBKO_01607 2.15e-203 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IAJLEBKO_01608 1.78e-316 yhdG - - E ko:K03294 - ko00000 amino acid
IAJLEBKO_01609 2.8e-265 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
IAJLEBKO_01610 8.62e-59 yhdK - - S - - - Sigma-M inhibitor protein
IAJLEBKO_01611 1.69e-257 yhdL - - S - - - Sigma factor regulator N-terminal
IAJLEBKO_01612 4.6e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IAJLEBKO_01613 8.84e-140 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
IAJLEBKO_01614 3.94e-307 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
IAJLEBKO_01615 1.97e-92 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
IAJLEBKO_01616 2.01e-286 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
IAJLEBKO_01617 4.51e-300 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IAJLEBKO_01618 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
IAJLEBKO_01619 2.48e-71 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IAJLEBKO_01620 4.54e-72 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IAJLEBKO_01621 2.89e-162 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
IAJLEBKO_01622 1.45e-08 yhdX - - S - - - Uncharacterized protein YhdX
IAJLEBKO_01623 1.91e-261 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
IAJLEBKO_01624 1.19e-179 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
IAJLEBKO_01625 4.69e-199 nodB1 - - G - - - deacetylase
IAJLEBKO_01626 5.67e-196 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
IAJLEBKO_01627 1e-113 pksA - - K - - - Transcriptional regulator
IAJLEBKO_01628 8.96e-123 ymcC - - S - - - Membrane
IAJLEBKO_01629 7.15e-110 - - - T - - - universal stress protein
IAJLEBKO_01631 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
IAJLEBKO_01632 0.0 yheH - - V ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
IAJLEBKO_01633 1.11e-141 yheG - - GM - - - NAD(P)H-binding
IAJLEBKO_01635 3.3e-39 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
IAJLEBKO_01636 2.12e-49 yheE - - S - - - Family of unknown function (DUF5342)
IAJLEBKO_01637 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
IAJLEBKO_01638 4.41e-272 yheC - - HJ - - - YheC/D like ATP-grasp
IAJLEBKO_01639 3.19e-263 yheB - - S - - - Belongs to the UPF0754 family
IAJLEBKO_01640 3.3e-70 yheA - - S - - - Belongs to the UPF0342 family
IAJLEBKO_01641 9.66e-256 yhaZ - - L - - - DNA alkylation repair enzyme
IAJLEBKO_01642 9.87e-204 yhaX - - S - - - haloacid dehalogenase-like hydrolase
IAJLEBKO_01643 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
IAJLEBKO_01644 2.89e-316 - 1.14.13.59 - Q ko:K03897 ko00310,ko01120,map00310,map01120 ko00000,ko00001,ko01000 L-lysine 6-monooxygenase (NADPH-requiring)
IAJLEBKO_01645 8.13e-266 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
IAJLEBKO_01646 8.88e-112 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
IAJLEBKO_01648 4.11e-175 yhaR - - I - - - enoyl-CoA hydratase
IAJLEBKO_01649 7.01e-20 - - - S - - - YhzD-like protein
IAJLEBKO_01650 5.34e-213 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IAJLEBKO_01651 2.05e-278 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
IAJLEBKO_01652 8.71e-299 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
IAJLEBKO_01653 0.0 yhaN - - L - - - AAA domain
IAJLEBKO_01654 2.48e-226 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
IAJLEBKO_01655 5.79e-43 yhaL - - S - - - Sporulation protein YhaL
IAJLEBKO_01656 1.53e-184 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IAJLEBKO_01657 1.29e-123 yhaK - - S - - - Putative zincin peptidase
IAJLEBKO_01658 1.2e-72 yhaI - - S - - - Protein of unknown function (DUF1878)
IAJLEBKO_01659 8.17e-147 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
IAJLEBKO_01660 4.74e-55 yhaH - - S - - - YtxH-like protein
IAJLEBKO_01661 2.55e-24 - - - - - - - -
IAJLEBKO_01662 8.25e-100 trpP - - S - - - Tryptophan transporter TrpP
IAJLEBKO_01663 1.69e-258 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IAJLEBKO_01664 8.27e-105 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
IAJLEBKO_01665 7.42e-174 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
IAJLEBKO_01666 9.11e-281 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
IAJLEBKO_01667 3.38e-159 ecsC - - S - - - EcsC protein family
IAJLEBKO_01668 9.88e-283 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
IAJLEBKO_01669 1.39e-311 yhfA - - C - - - membrane
IAJLEBKO_01670 3.1e-117 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
IAJLEBKO_01671 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
IAJLEBKO_01672 2.99e-258 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IAJLEBKO_01673 1.29e-231 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
IAJLEBKO_01674 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
IAJLEBKO_01675 3.1e-131 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
IAJLEBKO_01676 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
IAJLEBKO_01677 2.41e-234 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IAJLEBKO_01679 8.97e-252 yhfE - - G - - - peptidase M42
IAJLEBKO_01680 3.43e-282 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IAJLEBKO_01682 8.09e-181 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
IAJLEBKO_01683 1.85e-241 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
IAJLEBKO_01684 5.81e-139 yhfK - - GM - - - NmrA-like family
IAJLEBKO_01685 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
IAJLEBKO_01686 7.96e-85 yhfM - - - - - - -
IAJLEBKO_01687 1.24e-298 yhfN - - O - - - Peptidase M48
IAJLEBKO_01688 1.84e-260 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
IAJLEBKO_01689 4.24e-191 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
IAJLEBKO_01690 1.73e-133 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
IAJLEBKO_01691 5.84e-252 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
IAJLEBKO_01692 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
IAJLEBKO_01693 7.56e-116 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
IAJLEBKO_01694 3.24e-276 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
IAJLEBKO_01695 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
IAJLEBKO_01696 1.35e-204 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IAJLEBKO_01697 3.87e-42 yhzC - - S - - - IDEAL
IAJLEBKO_01698 1.09e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
IAJLEBKO_01699 9.09e-67 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
IAJLEBKO_01700 9.96e-82 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
IAJLEBKO_01701 1.49e-161 yrpD - - S - - - Domain of unknown function, YrpD
IAJLEBKO_01702 1.23e-57 yhjA - - S - - - Excalibur calcium-binding domain
IAJLEBKO_01703 7.56e-63 - - - S - - - Belongs to the UPF0145 family
IAJLEBKO_01704 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IAJLEBKO_01705 5.59e-37 yhjC - - S - - - Protein of unknown function (DUF3311)
IAJLEBKO_01706 4.12e-79 yhjD - - - - - - -
IAJLEBKO_01707 5.48e-143 yhjE - - S - - - SNARE associated Golgi protein
IAJLEBKO_01708 3.32e-119 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
IAJLEBKO_01709 0.0 yhjG - - CH - - - FAD binding domain
IAJLEBKO_01710 5.71e-121 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
IAJLEBKO_01711 1.99e-261 yhjN - - S ko:K07120 - ko00000 membrane
IAJLEBKO_01712 1.78e-266 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
IAJLEBKO_01713 3.71e-140 - - - K - - - QacR-like protein, C-terminal region
IAJLEBKO_01714 3.6e-122 yhjR - - S - - - Rubrerythrin
IAJLEBKO_01715 1.07e-152 ydfS - - S - - - Protein of unknown function (DUF421)
IAJLEBKO_01716 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
IAJLEBKO_01717 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
IAJLEBKO_01718 3.31e-283 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IAJLEBKO_01719 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
IAJLEBKO_01720 7.58e-67 yisB - - V - - - COG1403 Restriction endonuclease
IAJLEBKO_01721 6.66e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
IAJLEBKO_01722 1.61e-84 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
IAJLEBKO_01723 3e-33 gerPD - - S ko:K06302 - ko00000 Spore germination protein
IAJLEBKO_01724 8.51e-109 gerPC - - S ko:K06301 - ko00000 Spore germination protein
IAJLEBKO_01725 3.82e-47 gerPB - - S ko:K06300 - ko00000 cell differentiation
IAJLEBKO_01726 1.28e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
IAJLEBKO_01727 1.03e-11 yisI - - S - - - Spo0E like sporulation regulatory protein
IAJLEBKO_01728 1.04e-216 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
IAJLEBKO_01729 6.36e-78 yisL - - S - - - UPF0344 protein
IAJLEBKO_01730 1.07e-123 yisN - - S - - - Protein of unknown function (DUF2777)
IAJLEBKO_01731 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
IAJLEBKO_01732 7.37e-169 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
IAJLEBKO_01733 2.25e-312 yisQ - - V - - - Mate efflux family protein
IAJLEBKO_01734 1.35e-205 yisR - - K - - - Transcriptional regulator
IAJLEBKO_01735 2.46e-182 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
IAJLEBKO_01736 9.41e-195 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
IAJLEBKO_01737 1.08e-107 yisT - - S - - - DinB family
IAJLEBKO_01738 2.62e-109 yisX - - S - - - Pentapeptide repeats (9 copies)
IAJLEBKO_01739 5.16e-104 - - - S - - - Acetyltransferase (GNAT) domain
IAJLEBKO_01740 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
IAJLEBKO_01741 3.69e-78 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
IAJLEBKO_01742 4.36e-204 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
IAJLEBKO_01743 4.04e-217 - - - S ko:K07335 - ko00000 ABC transporter substrate-binding protein PnrA-like
IAJLEBKO_01744 2.77e-137 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
IAJLEBKO_01746 5.06e-199 yitS - - S - - - protein conserved in bacteria
IAJLEBKO_01747 6.56e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
IAJLEBKO_01748 8.76e-104 ipi - - S - - - Intracellular proteinase inhibitor
IAJLEBKO_01749 1.5e-36 - - - S - - - Protein of unknown function (DUF3813)
IAJLEBKO_01750 1.49e-11 - - - - - - - -
IAJLEBKO_01751 2.42e-195 - 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
IAJLEBKO_01752 1.06e-186 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
IAJLEBKO_01753 3.26e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
IAJLEBKO_01754 1.7e-94 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
IAJLEBKO_01755 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
IAJLEBKO_01756 1.18e-121 yitZ - - G - - - Major Facilitator Superfamily
IAJLEBKO_01757 1.23e-253 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IAJLEBKO_01758 2.99e-289 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IAJLEBKO_01759 5.17e-175 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
IAJLEBKO_01760 3.81e-275 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
IAJLEBKO_01761 1.34e-256 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
IAJLEBKO_01762 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
IAJLEBKO_01763 1.13e-222 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IAJLEBKO_01764 7.21e-39 yjzC - - S - - - YjzC-like protein
IAJLEBKO_01765 1.06e-32 yjzD - - S - - - Protein of unknown function (DUF2929)
IAJLEBKO_01766 5.47e-179 yjaU - - I - - - carboxylic ester hydrolase activity
IAJLEBKO_01767 1.32e-131 yjaV - - - - - - -
IAJLEBKO_01768 2.22e-211 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
IAJLEBKO_01769 6.46e-37 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
IAJLEBKO_01770 8.09e-44 yjzB - - - - - - -
IAJLEBKO_01771 7.63e-220 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IAJLEBKO_01772 3.86e-300 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IAJLEBKO_01773 1.84e-190 yjaZ - - O - - - Zn-dependent protease
IAJLEBKO_01774 6.88e-231 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IAJLEBKO_01775 1.03e-237 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IAJLEBKO_01776 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
IAJLEBKO_01777 1.16e-216 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAJLEBKO_01778 9.66e-198 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAJLEBKO_01779 1.52e-188 yjbA - - S - - - Belongs to the UPF0736 family
IAJLEBKO_01780 1.45e-233 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
IAJLEBKO_01781 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
IAJLEBKO_01782 2.53e-213 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAJLEBKO_01783 5.09e-210 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAJLEBKO_01784 1.5e-256 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IAJLEBKO_01785 1.22e-217 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IAJLEBKO_01786 2.88e-294 - - - S - - - Putative glycosyl hydrolase domain
IAJLEBKO_01787 7.3e-131 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IAJLEBKO_01788 2.47e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IAJLEBKO_01789 5.59e-141 yjbE - - P - - - Integral membrane protein TerC family
IAJLEBKO_01790 9.78e-150 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
IAJLEBKO_01791 2.49e-276 coiA - - S ko:K06198 - ko00000 Competence protein
IAJLEBKO_01792 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
IAJLEBKO_01793 3.14e-27 - - - - - - - -
IAJLEBKO_01794 6.05e-220 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
IAJLEBKO_01795 1.22e-93 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
IAJLEBKO_01796 2.99e-150 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
IAJLEBKO_01797 3.9e-123 yjbK - - S - - - protein conserved in bacteria
IAJLEBKO_01798 6.79e-79 yjbL - - S - - - Belongs to the UPF0738 family
IAJLEBKO_01799 9.01e-139 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
IAJLEBKO_01800 2.07e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IAJLEBKO_01801 1.42e-212 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
IAJLEBKO_01802 5.06e-182 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
IAJLEBKO_01803 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
IAJLEBKO_01804 2.71e-175 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IAJLEBKO_01805 4.68e-138 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
IAJLEBKO_01806 3.75e-267 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
IAJLEBKO_01807 4.53e-41 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 Thiamine biosynthesis
IAJLEBKO_01808 7.36e-173 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
IAJLEBKO_01809 2.07e-236 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IAJLEBKO_01810 3.03e-189 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
IAJLEBKO_01811 6.85e-180 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
IAJLEBKO_01812 6.53e-123 yjbX - - S - - - Spore coat protein
IAJLEBKO_01813 2.1e-108 cotZ - - S ko:K06344 - ko00000 Spore coat protein
IAJLEBKO_01814 4.28e-121 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
IAJLEBKO_01815 2.61e-100 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
IAJLEBKO_01816 8.38e-36 cotW - - - ko:K06341 - ko00000 -
IAJLEBKO_01817 2.67e-68 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
IAJLEBKO_01818 2.05e-73 yjcA - - S - - - Protein of unknown function (DUF1360)
IAJLEBKO_01822 2.57e-51 spoVIF - - S - - - Stage VI sporulation protein F
IAJLEBKO_01823 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
IAJLEBKO_01824 5e-48 - - - - - - - -
IAJLEBKO_01825 3.99e-179 blm 3.5.2.6 - S ko:K17837 ko01501,map01501 ko00000,ko00001,ko01000 Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
IAJLEBKO_01826 5.35e-159 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
IAJLEBKO_01827 4.81e-169 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
IAJLEBKO_01828 1.76e-47 - - - K - - - SpoVT / AbrB like domain
IAJLEBKO_01830 1.18e-94 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IAJLEBKO_01831 2.43e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
IAJLEBKO_01832 1.43e-163 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
IAJLEBKO_01833 8.87e-268 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
IAJLEBKO_01834 1.15e-279 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
IAJLEBKO_01836 2.2e-39 - - - - - - - -
IAJLEBKO_01837 7.58e-107 - - - - - - - -
IAJLEBKO_01838 6.63e-224 - - - S - - - Bacterial EndoU nuclease
IAJLEBKO_01839 5.61e-121 - - - - - - - -
IAJLEBKO_01841 8.05e-166 - - - - - - - -
IAJLEBKO_01842 4.36e-05 ywlA - - S - - - Uncharacterised protein family (UPF0715)
IAJLEBKO_01846 3.14e-76 - - - E - - - Glyoxalase-like domain
IAJLEBKO_01847 1.11e-208 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
IAJLEBKO_01848 1.81e-60 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
IAJLEBKO_01849 0.0 yfjF - - EGP - - - Belongs to the major facilitator superfamily
IAJLEBKO_01850 4.3e-106 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
IAJLEBKO_01851 4.29e-278 yvfO 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
IAJLEBKO_01852 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
IAJLEBKO_01853 2.34e-239 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
IAJLEBKO_01854 2.58e-275 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IAJLEBKO_01855 0.0 lacE 2.7.1.207 - G ko:K02761,ko:K02787,ko:K02788 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IAJLEBKO_01856 5.16e-66 celC 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IAJLEBKO_01857 0.0 lacG 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
IAJLEBKO_01858 1.19e-178 yulB - - K ko:K02530 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
IAJLEBKO_01859 1.1e-156 - - - S - - - Haloacid dehalogenase-like hydrolase
IAJLEBKO_01860 2.03e-190 - - - N - - - Kelch motif
IAJLEBKO_01862 2.48e-136 - - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
IAJLEBKO_01864 3.85e-31 yjfB - - S - - - Putative motility protein
IAJLEBKO_01865 2.76e-86 yjgA - - T - - - Protein of unknown function (DUF2809)
IAJLEBKO_01866 1.94e-129 yjgB - - S - - - Domain of unknown function (DUF4309)
IAJLEBKO_01867 0.0 - 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
IAJLEBKO_01868 2.2e-117 yjgD - - S - - - Protein of unknown function (DUF1641)
IAJLEBKO_01869 2.45e-286 yjiB 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
IAJLEBKO_01870 1.83e-280 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
IAJLEBKO_01871 1.73e-40 - - - - - - - -
IAJLEBKO_01872 2.65e-183 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
IAJLEBKO_01873 1.45e-158 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
IAJLEBKO_01874 8.84e-166 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 Belongs to the ABC transporter superfamily
IAJLEBKO_01875 1.38e-225 yjlA - - EG - - - Putative multidrug resistance efflux transporter
IAJLEBKO_01876 1.12e-114 yjlB - - S - - - Cupin domain
IAJLEBKO_01877 1.7e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
IAJLEBKO_01878 1.76e-279 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
IAJLEBKO_01879 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
IAJLEBKO_01880 0.0 - - - G ko:K03292 - ko00000 symporter YjmB
IAJLEBKO_01881 9.79e-233 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
IAJLEBKO_01882 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
IAJLEBKO_01883 0.0 uxaA 4.2.1.7 - G ko:K01685 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
IAJLEBKO_01884 2.6e-112 - - - T - - - Transcriptional regulatory protein, C terminal
IAJLEBKO_01885 1.05e-168 - - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
IAJLEBKO_01886 6.68e-20 - - - V ko:K01990,ko:K20459 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
IAJLEBKO_01888 7.56e-166 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
IAJLEBKO_01889 1.19e-102 yjoA - - S - - - DinB family
IAJLEBKO_01890 1.55e-274 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
IAJLEBKO_01892 1.84e-213 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
IAJLEBKO_01893 2.73e-80 yjqA - - S - - - Bacterial PH domain
IAJLEBKO_01894 7.55e-142 yjqB - - S - - - phage-related replication protein
IAJLEBKO_01896 7.61e-144 xkdA - - E - - - IrrE N-terminal-like domain
IAJLEBKO_01897 6.52e-75 xre - - K - - - Helix-turn-helix XRE-family like proteins
IAJLEBKO_01899 1.15e-191 xkdC - - L - - - Bacterial dnaA protein
IAJLEBKO_01903 1.02e-108 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
IAJLEBKO_01904 2.9e-141 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
IAJLEBKO_01905 8.55e-264 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
IAJLEBKO_01906 7.29e-303 xkdE3 - - S - - - portal protein
IAJLEBKO_01907 5.26e-118 xkdF3 - - L - - - Putative phage serine protease XkdF
IAJLEBKO_01908 2.9e-203 xkdG - - S - - - Phage capsid family
IAJLEBKO_01909 2.53e-60 yqbG - - S - - - Protein of unknown function (DUF3199)
IAJLEBKO_01910 1.17e-55 - - - S - - - Domain of unknown function (DUF3599)
IAJLEBKO_01911 4.86e-77 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
IAJLEBKO_01912 4.99e-73 xkdJ - - - - - - -
IAJLEBKO_01913 3.86e-21 - - - - - - - -
IAJLEBKO_01914 3.28e-287 xkdK - - S - - - Phage tail sheath C-terminal domain
IAJLEBKO_01915 8.21e-97 xkdM - - S - - - Phage tail tube protein
IAJLEBKO_01916 7.28e-96 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
IAJLEBKO_01917 4.33e-27 - - - - - - - -
IAJLEBKO_01920 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
IAJLEBKO_01921 2.06e-109 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
IAJLEBKO_01922 2.75e-244 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IAJLEBKO_01923 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IAJLEBKO_01924 1.23e-254 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
IAJLEBKO_01925 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IAJLEBKO_01926 3.1e-149 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IAJLEBKO_01927 2.25e-239 ysoA - - H - - - Tetratricopeptide repeat
IAJLEBKO_01928 2.18e-287 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IAJLEBKO_01929 3.83e-295 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IAJLEBKO_01930 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
IAJLEBKO_01931 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IAJLEBKO_01932 3.1e-138 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
IAJLEBKO_01933 3.93e-114 ysxD - - - - - - -
IAJLEBKO_01934 1.24e-314 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IAJLEBKO_01935 2.19e-185 hemX - - O ko:K02497 - ko00000 cytochrome C
IAJLEBKO_01936 1.05e-222 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
IAJLEBKO_01937 6.6e-181 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
IAJLEBKO_01938 1.02e-235 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
IAJLEBKO_01939 4.63e-312 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
IAJLEBKO_01940 1.36e-299 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
IAJLEBKO_01941 6.33e-250 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IAJLEBKO_01942 1.53e-35 - - - - - - - -
IAJLEBKO_01943 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IAJLEBKO_01944 2.09e-304 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
IAJLEBKO_01945 4.26e-170 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
IAJLEBKO_01946 4.22e-207 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
IAJLEBKO_01947 5.35e-127 maf - - D ko:K06287 - ko00000 septum formation protein Maf
IAJLEBKO_01948 7.15e-164 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
IAJLEBKO_01949 1.06e-234 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
IAJLEBKO_01950 2.51e-201 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
IAJLEBKO_01951 1.76e-110 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
IAJLEBKO_01952 6.85e-155 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
IAJLEBKO_01953 1.61e-183 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
IAJLEBKO_01954 1.39e-188 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
IAJLEBKO_01955 5.1e-206 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
IAJLEBKO_01956 1.28e-65 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
IAJLEBKO_01957 1.42e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
IAJLEBKO_01958 7.74e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
IAJLEBKO_01959 3.5e-138 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
IAJLEBKO_01960 2.37e-309 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IAJLEBKO_01961 5.94e-95 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
IAJLEBKO_01962 8.16e-206 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
IAJLEBKO_01963 1.18e-121 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
IAJLEBKO_01964 6.4e-282 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
IAJLEBKO_01965 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
IAJLEBKO_01966 4.13e-193 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
IAJLEBKO_01967 2.02e-270 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IAJLEBKO_01968 2.57e-248 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
IAJLEBKO_01969 2.21e-61 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IAJLEBKO_01971 1.03e-121 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
IAJLEBKO_01972 8.13e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IAJLEBKO_01973 3.57e-236 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IAJLEBKO_01974 2.8e-28 yrzS - - S - - - Protein of unknown function (DUF2905)
IAJLEBKO_01975 5.79e-246 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IAJLEBKO_01976 8.2e-293 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IAJLEBKO_01977 1.03e-50 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
IAJLEBKO_01978 9.08e-81 yrzE - - S - - - Protein of unknown function (DUF3792)
IAJLEBKO_01979 2.03e-143 yrbG - - S - - - membrane
IAJLEBKO_01980 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IAJLEBKO_01981 4.04e-67 yrzD - - S - - - Post-transcriptional regulator
IAJLEBKO_01982 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IAJLEBKO_01983 8.88e-112 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
IAJLEBKO_01984 7.78e-63 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
IAJLEBKO_01985 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
IAJLEBKO_01986 5.1e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IAJLEBKO_01987 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IAJLEBKO_01988 5.78e-97 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IAJLEBKO_01989 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
IAJLEBKO_01992 1e-308 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
IAJLEBKO_01993 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IAJLEBKO_01994 1.96e-177 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
IAJLEBKO_01995 3.74e-303 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
IAJLEBKO_01996 9.19e-84 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
IAJLEBKO_01997 2.98e-269 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
IAJLEBKO_01998 5.04e-282 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IAJLEBKO_01999 1.12e-23 yrrB - - S - - - COG0457 FOG TPR repeat
IAJLEBKO_02000 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IAJLEBKO_02001 1.69e-105 yrrD - - S - - - protein conserved in bacteria
IAJLEBKO_02002 8.4e-42 yrzR - - - - - - -
IAJLEBKO_02003 6.52e-13 - - - S - - - Protein of unknown function (DUF3918)
IAJLEBKO_02004 3.1e-138 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IAJLEBKO_02005 3.24e-139 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IAJLEBKO_02006 1.82e-188 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
IAJLEBKO_02007 3.66e-167 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
IAJLEBKO_02008 4.47e-235 yrrI - - S - - - AI-2E family transporter
IAJLEBKO_02009 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IAJLEBKO_02010 1.29e-54 yrzL - - S - - - Belongs to the UPF0297 family
IAJLEBKO_02011 2.72e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IAJLEBKO_02012 7.2e-61 yrzB - - S - - - Belongs to the UPF0473 family
IAJLEBKO_02013 4.48e-256 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IAJLEBKO_02014 2.22e-151 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
IAJLEBKO_02015 6.3e-222 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
IAJLEBKO_02016 1.09e-311 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
IAJLEBKO_02017 2.61e-147 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
IAJLEBKO_02018 1.62e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IAJLEBKO_02019 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
IAJLEBKO_02020 3.56e-124 yrrS - - S - - - Protein of unknown function (DUF1510)
IAJLEBKO_02021 1.78e-38 yrzA - - S - - - Protein of unknown function (DUF2536)
IAJLEBKO_02022 1.35e-150 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
IAJLEBKO_02023 5.64e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IAJLEBKO_02024 1.61e-218 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
IAJLEBKO_02025 7.59e-268 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
IAJLEBKO_02026 5.51e-46 yrhC - - S - - - YrhC-like protein
IAJLEBKO_02027 4.76e-106 yrhD - - S - - - Protein of unknown function (DUF1641)
IAJLEBKO_02028 0.0 yrhE 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
IAJLEBKO_02029 1.48e-78 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
IAJLEBKO_02030 3.96e-183 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
IAJLEBKO_02031 2.37e-07 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
IAJLEBKO_02032 2.12e-119 yrhH - - Q - - - methyltransferase
IAJLEBKO_02033 4.77e-130 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
IAJLEBKO_02034 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
IAJLEBKO_02035 2.18e-269 yybF1 - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
IAJLEBKO_02036 5.33e-211 yybE - - K - - - Transcriptional regulator
IAJLEBKO_02037 5.18e-104 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IAJLEBKO_02038 1.36e-228 romA - - S - - - Beta-lactamase superfamily domain
IAJLEBKO_02039 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
IAJLEBKO_02040 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IAJLEBKO_02041 7.78e-235 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
IAJLEBKO_02042 1.18e-167 - - - K - - - Helix-turn-helix domain, rpiR family
IAJLEBKO_02043 2.29e-184 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
IAJLEBKO_02044 3.82e-186 supH - - S - - - hydrolase
IAJLEBKO_02045 1.37e-120 - - - S - - - DinB family
IAJLEBKO_02046 1.01e-103 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
IAJLEBKO_02047 2.53e-278 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 COG0477 Permeases of the major facilitator superfamily
IAJLEBKO_02048 8.13e-05 - - - K - - - acetyltransferase
IAJLEBKO_02049 2.93e-123 yqaC - - F - - - adenylate kinase activity
IAJLEBKO_02050 1.6e-188 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
IAJLEBKO_02051 3.85e-120 - - - K - - - Transcriptional regulator PadR-like family
IAJLEBKO_02052 2.16e-203 - - - S - - - Carbohydrate esterase, sialic acid-specific acetylesterase
IAJLEBKO_02053 6.78e-160 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IAJLEBKO_02054 3.73e-269 - - - EGP - - - Transmembrane secretion effector
IAJLEBKO_02055 6.87e-137 yqeD - - S - - - SNARE associated Golgi protein
IAJLEBKO_02056 2.23e-178 pdaC 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
IAJLEBKO_02057 1.2e-176 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
IAJLEBKO_02059 3.19e-122 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
IAJLEBKO_02060 4.59e-271 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
IAJLEBKO_02061 1.7e-200 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IAJLEBKO_02062 1.81e-60 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
IAJLEBKO_02063 6.82e-139 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IAJLEBKO_02064 5.26e-132 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
IAJLEBKO_02065 9.39e-80 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IAJLEBKO_02066 4.86e-178 yqeM - - Q - - - Methyltransferase
IAJLEBKO_02067 4.85e-192 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IAJLEBKO_02068 1.69e-135 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
IAJLEBKO_02069 3.79e-136 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
IAJLEBKO_02070 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
IAJLEBKO_02071 7.42e-232 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
IAJLEBKO_02072 1.91e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
IAJLEBKO_02073 1.02e-259 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IAJLEBKO_02074 2.5e-277 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
IAJLEBKO_02075 3.5e-70 yqxA - - S - - - Protein of unknown function (DUF3679)
IAJLEBKO_02076 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IAJLEBKO_02077 7.65e-272 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
IAJLEBKO_02078 2.73e-240 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IAJLEBKO_02079 5.18e-110 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IAJLEBKO_02080 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
IAJLEBKO_02081 4.93e-266 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IAJLEBKO_02082 6.31e-223 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
IAJLEBKO_02083 1.44e-180 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IAJLEBKO_02084 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
IAJLEBKO_02085 9.26e-200 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
IAJLEBKO_02086 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
IAJLEBKO_02087 6.44e-90 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
IAJLEBKO_02088 1.34e-295 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
IAJLEBKO_02089 1.3e-174 yqfA - - S - - - UPF0365 protein
IAJLEBKO_02090 2.85e-82 yqfB - - - - - - -
IAJLEBKO_02091 3.57e-61 yqfC - - S - - - sporulation protein YqfC
IAJLEBKO_02092 3.72e-282 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
IAJLEBKO_02093 7.08e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
IAJLEBKO_02094 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
IAJLEBKO_02095 1.44e-104 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IAJLEBKO_02096 5.28e-83 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
IAJLEBKO_02097 1.92e-92 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
IAJLEBKO_02098 8.2e-214 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IAJLEBKO_02099 6e-24 - - - S - - - YqzL-like protein
IAJLEBKO_02100 5.05e-185 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
IAJLEBKO_02101 5.19e-223 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
IAJLEBKO_02102 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
IAJLEBKO_02103 5.89e-145 ccpN - - K - - - CBS domain
IAJLEBKO_02104 5.46e-192 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
IAJLEBKO_02105 1.36e-112 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
IAJLEBKO_02106 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IAJLEBKO_02107 3.97e-255 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IAJLEBKO_02108 1.95e-82 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
IAJLEBKO_02109 1.21e-161 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
IAJLEBKO_02110 2.54e-267 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IAJLEBKO_02111 5.01e-226 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IAJLEBKO_02112 1.95e-87 yqfQ - - S - - - YqfQ-like protein
IAJLEBKO_02113 1.05e-308 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IAJLEBKO_02114 7.01e-213 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IAJLEBKO_02115 8.63e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
IAJLEBKO_02116 6.35e-198 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
IAJLEBKO_02117 2.25e-100 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
IAJLEBKO_02118 5.81e-142 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
IAJLEBKO_02119 3.34e-80 yqfX - - S - - - membrane
IAJLEBKO_02120 1.97e-256 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IAJLEBKO_02121 3.05e-63 yqfZ - - M ko:K06417 - ko00000 LysM domain
IAJLEBKO_02122 2.44e-164 yqgB - - S - - - Protein of unknown function (DUF1189)
IAJLEBKO_02123 2.27e-98 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
IAJLEBKO_02124 1.72e-147 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
IAJLEBKO_02125 9.63e-289 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
IAJLEBKO_02126 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
IAJLEBKO_02127 9.5e-208 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
IAJLEBKO_02128 2.48e-203 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
IAJLEBKO_02129 3.26e-196 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
IAJLEBKO_02130 4.62e-183 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IAJLEBKO_02131 2.32e-188 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IAJLEBKO_02132 1.02e-98 yqzC - - S - - - Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IAJLEBKO_02133 3.42e-68 yqzD - - - - - - -
IAJLEBKO_02134 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
IAJLEBKO_02135 6.07e-126 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IAJLEBKO_02136 3.79e-11 yqgO - - - - - - -
IAJLEBKO_02137 7.52e-301 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
IAJLEBKO_02138 1.51e-37 yqgQ - - S - - - Protein conserved in bacteria
IAJLEBKO_02139 5.03e-229 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
IAJLEBKO_02140 3.14e-278 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
IAJLEBKO_02141 7.05e-252 yqgU - - - - - - -
IAJLEBKO_02142 2.02e-63 dglA - - S - - - Thiamine-binding protein
IAJLEBKO_02143 1.07e-28 yqgW - - S - - - Protein of unknown function (DUF2759)
IAJLEBKO_02144 2.84e-156 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
IAJLEBKO_02145 4.19e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
IAJLEBKO_02146 1.15e-86 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
IAJLEBKO_02148 1.96e-188 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IAJLEBKO_02149 7.58e-304 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
IAJLEBKO_02150 6.43e-239 yqxL - - P - - - Mg2 transporter protein
IAJLEBKO_02151 3.84e-258 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IAJLEBKO_02152 4.65e-233 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
IAJLEBKO_02153 4.46e-66 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
IAJLEBKO_02154 5.36e-92 - - - NU ko:K02246,ko:K08084 - ko00000,ko00002,ko02044 Tfp pilus assembly protein FimT
IAJLEBKO_02155 2.21e-26 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
IAJLEBKO_02156 1.82e-84 comGF - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
IAJLEBKO_02157 9.51e-81 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
IAJLEBKO_02158 2e-36 yqzE - - S - - - YqzE-like protein
IAJLEBKO_02159 1.97e-70 yqzG - - S - - - Protein of unknown function (DUF3889)
IAJLEBKO_02160 5.44e-155 yqxM - - - ko:K19433 - ko00000 -
IAJLEBKO_02161 8.95e-101 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
IAJLEBKO_02162 1.49e-180 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
IAJLEBKO_02163 2.75e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
IAJLEBKO_02164 2.31e-32 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
IAJLEBKO_02165 1.52e-195 yqhG - - S - - - Bacterial protein YqhG of unknown function
IAJLEBKO_02166 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
IAJLEBKO_02167 9.52e-264 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
IAJLEBKO_02168 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IAJLEBKO_02169 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IAJLEBKO_02170 3.18e-84 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
IAJLEBKO_02171 1.3e-203 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
IAJLEBKO_02172 5.64e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
IAJLEBKO_02173 2.85e-209 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
IAJLEBKO_02174 1.54e-82 yqhP - - - - - - -
IAJLEBKO_02175 7.33e-221 yqhQ - - S - - - Protein of unknown function (DUF1385)
IAJLEBKO_02176 1.82e-116 yqhR - - S - - - Conserved membrane protein YqhR
IAJLEBKO_02177 6.04e-249 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
IAJLEBKO_02178 6.82e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IAJLEBKO_02179 9.89e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
IAJLEBKO_02180 1.8e-220 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
IAJLEBKO_02181 9.44e-110 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
IAJLEBKO_02182 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
IAJLEBKO_02183 3.72e-55 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
IAJLEBKO_02184 5.23e-261 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
IAJLEBKO_02185 1.05e-130 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
IAJLEBKO_02186 3.34e-148 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
IAJLEBKO_02187 2.74e-94 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
IAJLEBKO_02188 1.63e-86 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IAJLEBKO_02189 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
IAJLEBKO_02190 1.36e-87 yqhY - - S - - - protein conserved in bacteria
IAJLEBKO_02191 2.58e-85 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IAJLEBKO_02192 3.05e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IAJLEBKO_02193 8.28e-310 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IAJLEBKO_02194 2.67e-52 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IAJLEBKO_02195 6.4e-204 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
IAJLEBKO_02196 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IAJLEBKO_02197 2.06e-197 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
IAJLEBKO_02198 4.38e-102 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
IAJLEBKO_02199 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
IAJLEBKO_02200 1.47e-302 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
IAJLEBKO_02201 1.23e-186 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
IAJLEBKO_02202 1.13e-271 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IAJLEBKO_02205 1.6e-272 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
IAJLEBKO_02207 2.32e-145 - - - K - - - Protein of unknown function (DUF1232)
IAJLEBKO_02208 1.96e-131 - - - P - - - Probably functions as a manganese efflux pump
IAJLEBKO_02210 1.97e-136 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
IAJLEBKO_02211 1.5e-172 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
IAJLEBKO_02212 1.08e-269 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
IAJLEBKO_02213 2.51e-199 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
IAJLEBKO_02214 4.85e-258 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
IAJLEBKO_02215 2.71e-258 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
IAJLEBKO_02216 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
IAJLEBKO_02217 1.56e-202 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IAJLEBKO_02218 6.25e-47 yqzF - - S - - - Protein of unknown function (DUF2627)
IAJLEBKO_02219 0.0 bkdR - - KT - - - Transcriptional regulator
IAJLEBKO_02220 2.27e-193 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
IAJLEBKO_02221 1.58e-261 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
IAJLEBKO_02222 2.23e-259 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
IAJLEBKO_02223 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IAJLEBKO_02224 1.86e-220 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IAJLEBKO_02225 1.7e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IAJLEBKO_02226 7.13e-276 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IAJLEBKO_02227 1.42e-217 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IAJLEBKO_02228 1.68e-99 yqiW - - S - - - Belongs to the UPF0403 family
IAJLEBKO_02229 1.37e-173 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
IAJLEBKO_02230 1.04e-141 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
IAJLEBKO_02231 6.07e-165 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
IAJLEBKO_02232 3.22e-219 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
IAJLEBKO_02233 3.7e-123 yqjB - - S - - - protein conserved in bacteria
IAJLEBKO_02235 1.89e-95 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
IAJLEBKO_02236 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
IAJLEBKO_02237 6.13e-258 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
IAJLEBKO_02238 2.91e-191 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IAJLEBKO_02239 1.3e-34 yqzJ - - - - - - -
IAJLEBKO_02240 1.35e-301 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IAJLEBKO_02241 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IAJLEBKO_02242 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IAJLEBKO_02243 3.23e-219 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IAJLEBKO_02244 5.05e-186 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IAJLEBKO_02245 9.28e-248 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
IAJLEBKO_02246 2.24e-66 - - - S - - - GlpM protein
IAJLEBKO_02247 6.22e-209 - - - K - - - LysR substrate binding domain
IAJLEBKO_02248 4.32e-122 nusG1 - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
IAJLEBKO_02249 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
IAJLEBKO_02252 3.73e-312 - 6.1.3.1, 6.2.1.3, 6.2.1.34 - IQ ko:K00666,ko:K01897,ko:K12508,ko:K22319 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
IAJLEBKO_02253 1.54e-165 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
IAJLEBKO_02254 9.07e-279 glcP1 - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
IAJLEBKO_02255 5.18e-313 gabT 2.6.1.19 - E ko:K00823 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IAJLEBKO_02256 2.38e-225 suhB 3.1.3.25, 3.1.3.7 - G ko:K01082,ko:K01092 ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070 ko00000,ko00001,ko00002,ko01000,ko03016 inositol monophosphate 1-phosphatase activity
IAJLEBKO_02257 6.88e-257 - 1.1.1.14, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00008 ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
IAJLEBKO_02258 2.74e-288 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
IAJLEBKO_02259 2.09e-220 ybaS - - S - - - Na -dependent transporter
IAJLEBKO_02260 6.15e-140 ybbA - - S ko:K07017 - ko00000 Putative esterase
IAJLEBKO_02261 1.43e-229 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAJLEBKO_02262 4.42e-226 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAJLEBKO_02263 2.98e-220 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
IAJLEBKO_02264 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
IAJLEBKO_02265 1.06e-298 ybbC - - S - - - protein conserved in bacteria
IAJLEBKO_02266 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
IAJLEBKO_02267 3.79e-310 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
IAJLEBKO_02268 4.31e-312 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IAJLEBKO_02269 3.68e-205 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IAJLEBKO_02270 1.01e-109 ybbJ - - J - - - acetyltransferase
IAJLEBKO_02271 3.89e-101 ybbK - - S - - - Protein of unknown function (DUF523)
IAJLEBKO_02277 4.59e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IAJLEBKO_02278 3.19e-151 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
IAJLEBKO_02279 1.82e-187 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IAJLEBKO_02280 8.64e-299 ybbR - - S - - - protein conserved in bacteria
IAJLEBKO_02281 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IAJLEBKO_02282 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IAJLEBKO_02283 6.13e-199 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
IAJLEBKO_02284 8.23e-138 - - - S - - - ABC-2 family transporter protein
IAJLEBKO_02285 9.2e-126 ybdN - - - - - - -
IAJLEBKO_02286 1.06e-165 ybdO - - S - - - Domain of unknown function (DUF4885)
IAJLEBKO_02287 2.43e-205 dkgB - - S - - - Aldo/keto reductase family
IAJLEBKO_02288 6.05e-135 yxaC - - M - - - effector of murein hydrolase
IAJLEBKO_02289 2.32e-66 - - - S ko:K06518 - ko00000,ko02000 LrgA family
IAJLEBKO_02290 5.62e-93 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
IAJLEBKO_02291 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
IAJLEBKO_02292 2.51e-117 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
IAJLEBKO_02293 7.94e-252 - - - T - - - COG4585 Signal transduction histidine kinase
IAJLEBKO_02294 7.12e-142 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
IAJLEBKO_02295 5.1e-213 yfiL - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
IAJLEBKO_02296 2.05e-259 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
IAJLEBKO_02297 1.64e-246 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
IAJLEBKO_02298 1.87e-32 - - - - - - - -
IAJLEBKO_02299 6.33e-104 - - - S - - - Domain of unknown function (DUF4879)
IAJLEBKO_02300 7.13e-52 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
IAJLEBKO_02301 2.93e-143 yqeB - - - - - - -
IAJLEBKO_02302 7.84e-55 ybyB - - - - - - -
IAJLEBKO_02303 0.0 ybeC - - E - - - amino acid
IAJLEBKO_02304 4.93e-212 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
IAJLEBKO_02305 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
IAJLEBKO_02306 4.08e-23 - - - S - - - Protein of unknown function (DUF2651)
IAJLEBKO_02307 4.74e-266 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
IAJLEBKO_02309 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
IAJLEBKO_02310 1.05e-46 - - - - - - - -
IAJLEBKO_02311 1.69e-107 - - - K - - - Helix-turn-helix XRE-family like proteins
IAJLEBKO_02312 2.55e-247 ypjH - - C ko:K08317 - ko00000,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
IAJLEBKO_02313 6.53e-271 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IAJLEBKO_02314 3.15e-120 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IAJLEBKO_02315 4.26e-113 ybfM - - S - - - SNARE associated Golgi protein
IAJLEBKO_02316 1.24e-193 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
IAJLEBKO_02317 1.5e-55 ybfN - - - - - - -
IAJLEBKO_02318 9.56e-244 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
IAJLEBKO_02319 6.75e-271 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IAJLEBKO_02320 1.44e-255 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
IAJLEBKO_02321 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
IAJLEBKO_02322 2.92e-230 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
IAJLEBKO_02323 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
IAJLEBKO_02324 3.06e-238 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
IAJLEBKO_02325 1.5e-270 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IAJLEBKO_02326 4.77e-220 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
IAJLEBKO_02327 2.39e-11 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
IAJLEBKO_02328 1.03e-93 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
IAJLEBKO_02329 2.81e-34 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
IAJLEBKO_02330 7.1e-197 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IAJLEBKO_02331 1.57e-141 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
IAJLEBKO_02332 1.24e-234 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
IAJLEBKO_02333 4.64e-83 ydfP - - S ko:K15977 - ko00000 DoxX
IAJLEBKO_02334 5.37e-74 ydfQ - - CO - - - Thioredoxin
IAJLEBKO_02335 1.63e-82 ycbP - - S - - - Protein of unknown function (DUF2512)
IAJLEBKO_02336 1.75e-100 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
IAJLEBKO_02337 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
IAJLEBKO_02338 8.68e-36 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
IAJLEBKO_02339 5.31e-155 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IAJLEBKO_02340 1.91e-151 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IAJLEBKO_02341 1.84e-261 ycbU - - E - - - Selenocysteine lyase
IAJLEBKO_02342 2.5e-313 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
IAJLEBKO_02343 6.03e-128 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
IAJLEBKO_02344 1.21e-248 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
IAJLEBKO_02345 8.07e-148 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
IAJLEBKO_02346 1.61e-250 yccF - - K ko:K07039 - ko00000 SEC-C motif
IAJLEBKO_02347 7.3e-217 yccK - - C - - - Aldo keto reductase
IAJLEBKO_02348 2.66e-225 ycdA - - S - - - Domain of unknown function (DUF5105)
IAJLEBKO_02349 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IAJLEBKO_02350 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IAJLEBKO_02351 1.72e-119 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
IAJLEBKO_02352 2.86e-248 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
IAJLEBKO_02353 4.28e-179 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
IAJLEBKO_02354 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
IAJLEBKO_02355 7.35e-214 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
IAJLEBKO_02356 2.82e-170 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
IAJLEBKO_02357 6.86e-174 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
IAJLEBKO_02358 3.3e-235 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAJLEBKO_02359 4.06e-140 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
IAJLEBKO_02360 7.32e-136 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
IAJLEBKO_02361 2.46e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
IAJLEBKO_02362 2.12e-178 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
IAJLEBKO_02363 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
IAJLEBKO_02364 1.12e-244 yceH - - P - - - Belongs to the TelA family
IAJLEBKO_02365 3.52e-274 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
IAJLEBKO_02366 7.71e-294 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
IAJLEBKO_02367 2.45e-185 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
IAJLEBKO_02368 1.16e-209 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
IAJLEBKO_02369 7.29e-267 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
IAJLEBKO_02370 1.48e-289 ycgA - - S - - - Membrane
IAJLEBKO_02371 2.55e-105 ycgB - - - - - - -
IAJLEBKO_02372 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
IAJLEBKO_02373 8.99e-226 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
IAJLEBKO_02374 0.0 mdr - - EGP - - - the major facilitator superfamily
IAJLEBKO_02375 6.92e-101 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
IAJLEBKO_02376 3.57e-144 ycgF - - E - - - Lysine exporter protein LysE YggA
IAJLEBKO_02377 1.71e-191 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
IAJLEBKO_02378 3.84e-313 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
IAJLEBKO_02379 3.22e-146 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
IAJLEBKO_02380 1.29e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IAJLEBKO_02381 3.92e-06 - - - S - - - Bacillus cereus group antimicrobial protein
IAJLEBKO_02382 2.74e-140 tmrB - - S - - - AAA domain
IAJLEBKO_02383 2.22e-187 - 4.2.1.118 - G ko:K15652 ko00400,ko01110,ko01130,map00400,map01110,map01130 ko00000,ko00001,ko01000 Xylose isomerase-like TIM barrel
IAJLEBKO_02384 2.02e-289 - - - G ko:K08191,ko:K08194 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
IAJLEBKO_02385 1.01e-134 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IAJLEBKO_02386 8.08e-234 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
IAJLEBKO_02387 5.05e-188 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
IAJLEBKO_02388 1.12e-215 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
IAJLEBKO_02389 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
IAJLEBKO_02390 1.1e-311 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IAJLEBKO_02391 1.43e-290 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
IAJLEBKO_02392 1.93e-241 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
IAJLEBKO_02393 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
IAJLEBKO_02394 5.73e-73 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
IAJLEBKO_02395 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IAJLEBKO_02396 3.21e-286 yciC - - S - - - GTPases (G3E family)
IAJLEBKO_02397 1.02e-280 fdh 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
IAJLEBKO_02398 1.32e-94 yckC - - S - - - membrane
IAJLEBKO_02399 1.46e-64 - - - S - - - Protein of unknown function (DUF2680)
IAJLEBKO_02400 1.58e-13 yckE 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
IAJLEBKO_02401 1.27e-86 nin - - S - - - Competence protein J (ComJ)
IAJLEBKO_02402 1.88e-101 nucA - - M - - - Deoxyribonuclease NucA/NucB
IAJLEBKO_02403 1.54e-124 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
IAJLEBKO_02404 1.05e-137 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
IAJLEBKO_02405 1.38e-82 hxlR - - K - - - transcriptional
IAJLEBKO_02406 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IAJLEBKO_02407 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IAJLEBKO_02408 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
IAJLEBKO_02409 6.15e-180 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
IAJLEBKO_02410 2.48e-315 - - - E - - - Aminotransferase class I and II
IAJLEBKO_02411 5.28e-167 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
IAJLEBKO_02412 9.99e-141 yczE - - S ko:K07149 - ko00000 membrane
IAJLEBKO_02413 3.95e-169 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
IAJLEBKO_02414 4.99e-154 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
IAJLEBKO_02415 2.8e-187 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
IAJLEBKO_02416 5.96e-206 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
IAJLEBKO_02417 1.4e-129 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
IAJLEBKO_02418 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
IAJLEBKO_02419 4.71e-51 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
IAJLEBKO_02420 1.67e-100 yclD - - - - - - -
IAJLEBKO_02421 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
IAJLEBKO_02422 0.0 yclG - - M - - - Pectate lyase superfamily protein
IAJLEBKO_02424 0.0 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
IAJLEBKO_02425 2.31e-299 gerKC - - S ko:K06297 - ko00000 spore germination
IAJLEBKO_02426 2.27e-249 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
IAJLEBKO_02427 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAJLEBKO_02428 6.05e-118 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IAJLEBKO_02429 1.43e-179 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
IAJLEBKO_02430 2.11e-148 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
IAJLEBKO_02431 5.6e-170 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
IAJLEBKO_02432 1.97e-276 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
IAJLEBKO_02433 6.13e-313 yxeQ - - S - - - MmgE/PrpD family
IAJLEBKO_02434 3.66e-155 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
IAJLEBKO_02435 1.74e-309 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
IAJLEBKO_02436 3.04e-163 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IAJLEBKO_02437 0.0 yclK - - T - - - COG0642 Signal transduction histidine kinase
IAJLEBKO_02438 2.72e-98 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
IAJLEBKO_02440 4.58e-316 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
IAJLEBKO_02441 1.1e-210 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAJLEBKO_02442 1.4e-212 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAJLEBKO_02443 1.61e-175 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
IAJLEBKO_02444 3.24e-222 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
IAJLEBKO_02445 3.99e-313 ycnB - - EGP - - - the major facilitator superfamily
IAJLEBKO_02446 1.23e-194 ycnC - - K - - - Transcriptional regulator
IAJLEBKO_02447 1.38e-174 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Nitroreductase family
IAJLEBKO_02448 1.97e-59 ycnE - - S - - - Monooxygenase
IAJLEBKO_02449 3.92e-70 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
IAJLEBKO_02450 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IAJLEBKO_02451 1.71e-284 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IAJLEBKO_02452 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IAJLEBKO_02453 8.27e-191 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
IAJLEBKO_02454 2.4e-186 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IAJLEBKO_02455 4.83e-130 ycnI - - S - - - protein conserved in bacteria
IAJLEBKO_02456 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
IAJLEBKO_02457 4.98e-137 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
IAJLEBKO_02458 9.6e-73 - - - - - - - -
IAJLEBKO_02459 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
IAJLEBKO_02460 4.11e-95 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
IAJLEBKO_02461 1.06e-259 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
IAJLEBKO_02462 2.89e-87 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
IAJLEBKO_02464 2.69e-177 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
IAJLEBKO_02465 7.14e-180 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
IAJLEBKO_02466 2.54e-269 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
IAJLEBKO_02467 1.15e-190 ycsI - - S - - - Belongs to the D-glutamate cyclase family
IAJLEBKO_02468 6.36e-173 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
IAJLEBKO_02469 4.91e-240 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
IAJLEBKO_02470 4.65e-167 kipR - - K - - - Transcriptional regulator
IAJLEBKO_02471 3.86e-150 ycsK - - E - - - anatomical structure formation involved in morphogenesis
IAJLEBKO_02473 5.95e-75 yczJ - - S - - - biosynthesis
IAJLEBKO_02474 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
IAJLEBKO_02475 3e-220 ycsN - - S - - - Oxidoreductase
IAJLEBKO_02476 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
IAJLEBKO_02477 0.0 ydaB - - IQ - - - acyl-CoA ligase
IAJLEBKO_02478 1.28e-205 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IAJLEBKO_02479 3.91e-125 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
IAJLEBKO_02480 4.04e-149 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IAJLEBKO_02481 1.83e-101 ydaG - - S - - - general stress protein
IAJLEBKO_02482 7.59e-178 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
IAJLEBKO_02483 6.54e-63 ydzA - - EGP - - - Domain of unknown function (DUF3817)
IAJLEBKO_02484 3.25e-97 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
IAJLEBKO_02485 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IAJLEBKO_02486 1.56e-255 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
IAJLEBKO_02487 2.19e-188 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
IAJLEBKO_02488 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
IAJLEBKO_02489 2.63e-302 ydaM - - M - - - Glycosyl transferase family group 2
IAJLEBKO_02490 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
IAJLEBKO_02491 0.0 ydaO - - E - - - amino acid
IAJLEBKO_02492 8.5e-95 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
IAJLEBKO_02493 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
IAJLEBKO_02494 1.68e-57 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
IAJLEBKO_02495 1.26e-98 - - - - - - - -
IAJLEBKO_02497 2.25e-265 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
IAJLEBKO_02499 2.7e-19 - - - - - - - -
IAJLEBKO_02501 4.89e-112 - - - - - - - -
IAJLEBKO_02502 1.41e-128 - - - - - - - -
IAJLEBKO_02503 7.18e-52 - - - - - - - -
IAJLEBKO_02504 5.35e-288 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
IAJLEBKO_02506 1.95e-45 ydaT - - - - - - -
IAJLEBKO_02507 4.08e-71 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
IAJLEBKO_02508 2.19e-181 ydbA - - P - - - EcsC protein family
IAJLEBKO_02509 5.59e-17 res - - L - - - Resolvase, N terminal domain
IAJLEBKO_02510 1.09e-65 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
IAJLEBKO_02511 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 Type I restriction-modification system
IAJLEBKO_02512 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
IAJLEBKO_02516 1.85e-115 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
IAJLEBKO_02517 4.55e-131 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IAJLEBKO_02518 4.12e-170 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IAJLEBKO_02519 2.58e-254 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
IAJLEBKO_02520 1.15e-196 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
IAJLEBKO_02521 1.08e-96 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
IAJLEBKO_02522 6.32e-42 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
IAJLEBKO_02523 2.19e-100 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
IAJLEBKO_02524 4.34e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
IAJLEBKO_02525 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
IAJLEBKO_02526 2.73e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
IAJLEBKO_02527 7.02e-103 yslB - - S - - - Protein of unknown function (DUF2507)
IAJLEBKO_02528 1.01e-273 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
IAJLEBKO_02529 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IAJLEBKO_02530 1.6e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
IAJLEBKO_02531 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
IAJLEBKO_02532 1.43e-226 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
IAJLEBKO_02533 4.1e-176 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
IAJLEBKO_02534 1.43e-177 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
IAJLEBKO_02535 1.78e-133 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
IAJLEBKO_02536 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
IAJLEBKO_02537 4.82e-114 ywbB - - S - - - Protein of unknown function (DUF2711)
IAJLEBKO_02538 3.09e-88 yshE - - S ko:K08989 - ko00000 membrane
IAJLEBKO_02539 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IAJLEBKO_02540 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
IAJLEBKO_02541 1.42e-107 yshB - - S - - - membrane protein, required for colicin V production
IAJLEBKO_02542 4.23e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IAJLEBKO_02543 7.57e-216 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IAJLEBKO_02544 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IAJLEBKO_02545 2.19e-249 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IAJLEBKO_02546 4.63e-173 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IAJLEBKO_02547 1.07e-43 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
IAJLEBKO_02548 2.81e-258 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
IAJLEBKO_02549 0.0 - 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD binding domain
IAJLEBKO_02550 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
IAJLEBKO_02551 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
IAJLEBKO_02552 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
IAJLEBKO_02553 1.18e-191 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
IAJLEBKO_02554 1.78e-214 araP - - P ko:K10189,ko:K10241,ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PFAM binding-protein-dependent transport systems inner membrane component
IAJLEBKO_02555 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
IAJLEBKO_02556 2.24e-283 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
IAJLEBKO_02557 2.93e-179 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
IAJLEBKO_02558 3.43e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
IAJLEBKO_02559 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
IAJLEBKO_02560 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
IAJLEBKO_02561 8.14e-240 abnA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
IAJLEBKO_02562 1.85e-263 ysdC - - G - - - COG1363 Cellulase M and related proteins
IAJLEBKO_02563 3.13e-86 ysdB - - S - - - Sigma-w pathway protein YsdB
IAJLEBKO_02564 5.44e-56 ysdA - - S - - - Membrane
IAJLEBKO_02565 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IAJLEBKO_02566 1.95e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
IAJLEBKO_02567 1.79e-112 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IAJLEBKO_02568 2.09e-145 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
IAJLEBKO_02569 9.13e-66 - - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 effector of murein hydrolase LrgA
IAJLEBKO_02570 4.27e-167 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
IAJLEBKO_02571 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IAJLEBKO_02572 5.69e-191 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
IAJLEBKO_02573 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IAJLEBKO_02574 1.63e-196 ytxC - - S - - - YtxC-like family
IAJLEBKO_02575 3.51e-137 ytxB - - S - - - SNARE associated Golgi protein
IAJLEBKO_02576 2.87e-219 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
IAJLEBKO_02577 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
IAJLEBKO_02578 5.95e-106 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IAJLEBKO_02579 1.82e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
IAJLEBKO_02580 8.56e-247 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IAJLEBKO_02581 1.69e-89 ytcD - - K - - - Transcriptional regulator
IAJLEBKO_02582 6.56e-258 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
IAJLEBKO_02583 4.54e-205 ytbE - - S - - - reductase
IAJLEBKO_02584 3.43e-127 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IAJLEBKO_02585 5.73e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
IAJLEBKO_02586 1.64e-201 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IAJLEBKO_02587 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IAJLEBKO_02588 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
IAJLEBKO_02589 2.9e-167 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IAJLEBKO_02590 3.62e-218 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
IAJLEBKO_02591 5.36e-308 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
IAJLEBKO_02592 2.86e-268 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
IAJLEBKO_02595 1.09e-254 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Aspartate phosphatase response regulator
IAJLEBKO_02596 7.64e-69 - - - - - - - -
IAJLEBKO_02597 1.84e-81 yjdF3 - - S - - - Protein of unknown function (DUF2992)
IAJLEBKO_02598 5.65e-96 ytwI - - S - - - membrane
IAJLEBKO_02599 4.05e-247 ytvI - - S - - - sporulation integral membrane protein YtvI
IAJLEBKO_02600 2.41e-84 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
IAJLEBKO_02601 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
IAJLEBKO_02602 1.14e-229 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IAJLEBKO_02603 1.34e-231 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
IAJLEBKO_02604 3.59e-207 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IAJLEBKO_02605 2.45e-286 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
IAJLEBKO_02606 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
IAJLEBKO_02607 4.94e-75 ytrH - - S - - - Sporulation protein YtrH
IAJLEBKO_02608 4.38e-113 ytrI - - - - - - -
IAJLEBKO_02609 1e-31 - - - - - - - -
IAJLEBKO_02610 2.14e-231 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
IAJLEBKO_02611 3.57e-62 ytpI - - S - - - YtpI-like protein
IAJLEBKO_02612 1.29e-301 ytoI - - K - - - transcriptional regulator containing CBS domains
IAJLEBKO_02613 4.86e-165 ytkL - - S - - - Belongs to the UPF0173 family
IAJLEBKO_02614 1.98e-182 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IAJLEBKO_02616 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
IAJLEBKO_02617 3.03e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
IAJLEBKO_02618 3.31e-114 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
IAJLEBKO_02619 1.57e-279 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IAJLEBKO_02620 1.69e-231 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
IAJLEBKO_02621 1.12e-115 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IAJLEBKO_02622 4.77e-100 ytfJ - - S - - - Sporulation protein YtfJ
IAJLEBKO_02623 1.26e-147 ytfI - - S - - - Protein of unknown function (DUF2953)
IAJLEBKO_02624 2.77e-114 yteJ - - S - - - RDD family
IAJLEBKO_02625 6.39e-235 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
IAJLEBKO_02626 3.16e-194 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IAJLEBKO_02627 0.0 ytcJ - - S - - - amidohydrolase
IAJLEBKO_02628 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
IAJLEBKO_02629 2.05e-42 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
IAJLEBKO_02630 4.05e-285 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IAJLEBKO_02631 2.25e-265 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
IAJLEBKO_02632 1.32e-306 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
IAJLEBKO_02633 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IAJLEBKO_02634 1.46e-196 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
IAJLEBKO_02635 2.41e-141 yttP - - K - - - Transcriptional regulator
IAJLEBKO_02636 2.04e-110 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
IAJLEBKO_02637 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
IAJLEBKO_02638 5.75e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IAJLEBKO_02639 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
IAJLEBKO_02640 2.48e-130 yokH - - G - - - SMI1 / KNR4 family
IAJLEBKO_02642 4.78e-66 - - - - - - - -
IAJLEBKO_02645 1.18e-06 - - - S - - - Phage-like element PBSX protein XtrA
IAJLEBKO_02646 6.07e-20 - - - - - - - -
IAJLEBKO_02647 8.81e-39 dnaC 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
IAJLEBKO_02648 3.57e-281 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IAJLEBKO_02650 1.93e-117 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
IAJLEBKO_02652 9.35e-174 - - - E - - - GDSL-like Lipase/Acylhydrolase family
IAJLEBKO_02653 3.93e-190 - - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IAJLEBKO_02654 1.06e-188 - - - K - - - Transcriptional regulator
IAJLEBKO_02655 9.98e-161 ygaZ - - E - - - AzlC protein
IAJLEBKO_02656 2.07e-62 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
IAJLEBKO_02657 3.46e-303 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IAJLEBKO_02658 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
IAJLEBKO_02659 2.84e-155 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
IAJLEBKO_02660 3.42e-149 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
IAJLEBKO_02661 9.2e-289 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
IAJLEBKO_02662 3.51e-154 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
IAJLEBKO_02663 5.2e-186 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
IAJLEBKO_02664 5.91e-235 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
IAJLEBKO_02665 1.54e-249 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
IAJLEBKO_02666 5.67e-56 ytxJ - - O - - - Protein of unknown function (DUF2847)
IAJLEBKO_02667 1.83e-30 ytxH - - S - - - COG4980 Gas vesicle protein
IAJLEBKO_02668 5.38e-26 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IAJLEBKO_02669 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
IAJLEBKO_02670 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
IAJLEBKO_02671 2.08e-139 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IAJLEBKO_02672 1.69e-190 ytpQ - - S - - - Belongs to the UPF0354 family
IAJLEBKO_02673 5.47e-76 ytpP - - CO - - - Thioredoxin
IAJLEBKO_02674 3.91e-100 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
IAJLEBKO_02675 4.33e-260 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
IAJLEBKO_02676 9.96e-69 ytzB - - S - - - small secreted protein
IAJLEBKO_02677 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
IAJLEBKO_02678 5.12e-207 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
IAJLEBKO_02679 6.43e-160 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IAJLEBKO_02680 3.88e-60 ytzH - - S - - - YtzH-like protein
IAJLEBKO_02681 2.93e-199 ytmP - - M - - - Phosphotransferase
IAJLEBKO_02682 1.61e-224 ytlR - - I - - - Diacylglycerol kinase catalytic domain
IAJLEBKO_02683 3.58e-212 ytlQ - - - - - - -
IAJLEBKO_02684 6.34e-132 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
IAJLEBKO_02685 6.81e-222 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
IAJLEBKO_02686 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
IAJLEBKO_02687 1.42e-288 pbuO - - S ko:K06901 - ko00000,ko02000 permease
IAJLEBKO_02688 3.53e-276 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
IAJLEBKO_02689 5.44e-165 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
IAJLEBKO_02690 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
IAJLEBKO_02691 8.33e-167 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
IAJLEBKO_02692 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IAJLEBKO_02693 5.3e-299 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
IAJLEBKO_02694 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
IAJLEBKO_02695 2.14e-36 yteV - - S - - - Sporulation protein Cse60
IAJLEBKO_02696 1.29e-237 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
IAJLEBKO_02697 4.42e-308 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
IAJLEBKO_02698 5.58e-218 - - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IAJLEBKO_02699 2.37e-183 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
IAJLEBKO_02700 9.62e-317 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
IAJLEBKO_02701 1.98e-110 - - - M - - - Acetyltransferase (GNAT) domain
IAJLEBKO_02702 6.05e-69 ytwF - - P - - - Sulfurtransferase
IAJLEBKO_02703 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
IAJLEBKO_02704 7.19e-69 ytvB - - S - - - Protein of unknown function (DUF4257)
IAJLEBKO_02705 1.32e-174 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
IAJLEBKO_02706 6.76e-269 yttB - - EGP - - - Major facilitator superfamily
IAJLEBKO_02707 1.47e-157 ywaF - - S - - - Integral membrane protein
IAJLEBKO_02708 0.0 bceB - - V ko:K02004,ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
IAJLEBKO_02709 3.81e-173 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
IAJLEBKO_02710 3.54e-221 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
IAJLEBKO_02711 3.69e-166 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IAJLEBKO_02712 3.9e-287 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
IAJLEBKO_02713 3.01e-161 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
IAJLEBKO_02714 1.58e-201 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
IAJLEBKO_02715 1.19e-231 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
IAJLEBKO_02716 7.78e-216 ytrC - - S ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
IAJLEBKO_02717 1.03e-207 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
IAJLEBKO_02718 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
IAJLEBKO_02720 7.09e-53 ytzC - - S - - - Protein of unknown function (DUF2524)
IAJLEBKO_02721 3.11e-247 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
IAJLEBKO_02722 0.0 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
IAJLEBKO_02723 6.73e-244 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
IAJLEBKO_02724 1.26e-136 ytqB - - J - - - Putative rRNA methylase
IAJLEBKO_02726 4.1e-182 - 3.1.4.46, 5.4.2.11 - C ko:K01126,ko:K01834 ko00010,ko00260,ko00564,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00564,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 glycerophosphoryl diester phosphodiesterase
IAJLEBKO_02727 2.02e-271 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
IAJLEBKO_02728 6.95e-194 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
IAJLEBKO_02729 8.19e-84 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IAJLEBKO_02730 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
IAJLEBKO_02731 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
IAJLEBKO_02732 7.88e-287 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IAJLEBKO_02733 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
IAJLEBKO_02734 2.85e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
IAJLEBKO_02735 7.79e-190 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
IAJLEBKO_02736 2.93e-235 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
IAJLEBKO_02737 6.12e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
IAJLEBKO_02738 7.52e-174 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
IAJLEBKO_02739 1.01e-114 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
IAJLEBKO_02740 3.51e-79 ytkC - - S - - - Bacteriophage holin family
IAJLEBKO_02741 3e-98 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
IAJLEBKO_02743 4.95e-98 ytkA - - S - - - YtkA-like
IAJLEBKO_02744 7.16e-114 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IAJLEBKO_02745 6.93e-53 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
IAJLEBKO_02746 9.31e-137 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
IAJLEBKO_02747 7.13e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
IAJLEBKO_02748 4.48e-313 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
IAJLEBKO_02749 1.49e-233 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
IAJLEBKO_02750 3.2e-33 - - - S - - - Domain of Unknown Function (DUF1540)
IAJLEBKO_02751 1.17e-271 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
IAJLEBKO_02752 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
IAJLEBKO_02753 6.18e-199 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IAJLEBKO_02754 2.42e-197 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
IAJLEBKO_02755 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
IAJLEBKO_02756 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
IAJLEBKO_02757 1.18e-166 yteA - - T - - - COG1734 DnaK suppressor protein
IAJLEBKO_02758 7.42e-102 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
IAJLEBKO_02778 2.93e-233 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IAJLEBKO_02779 4.41e-137 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
IAJLEBKO_02780 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
IAJLEBKO_02781 1.3e-69 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
IAJLEBKO_02782 3.78e-137 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
IAJLEBKO_02783 0.0 - - - EGP - - - Sugar (and other) transporter
IAJLEBKO_02784 3.21e-267 yraM - - S - - - PrpF protein
IAJLEBKO_02785 3.34e-210 yraN - - K - - - Transcriptional regulator
IAJLEBKO_02786 3.74e-136 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IAJLEBKO_02787 3.17e-234 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
IAJLEBKO_02788 4.72e-284 rafB - - P ko:K02532 - ko00000,ko02000 LacY proton/sugar symporter
IAJLEBKO_02789 0.0 cscA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
IAJLEBKO_02791 1.31e-45 - - - - - - - -
IAJLEBKO_02792 3.94e-125 - - - I - - - Pfam Lipase (class 3)
IAJLEBKO_02793 2.86e-18 - - - S - - - Protein of unknown function (DUF1433)
IAJLEBKO_02794 1.01e-120 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
IAJLEBKO_02795 3.16e-118 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IAJLEBKO_02796 1.06e-145 yyaS - - S ko:K07149 - ko00000 Membrane
IAJLEBKO_02797 1.91e-125 ywjB - - H - - - RibD C-terminal domain
IAJLEBKO_02799 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
IAJLEBKO_02800 6.96e-100 - - - K ko:K19417 - ko00000,ko03000 transcriptional
IAJLEBKO_02801 7.89e-154 epsA - - M ko:K19420 - ko00000 biosynthesis protein
IAJLEBKO_02802 3.12e-151 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
IAJLEBKO_02803 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
IAJLEBKO_02804 3.53e-277 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
IAJLEBKO_02805 3.2e-205 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
IAJLEBKO_02806 2.88e-271 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
IAJLEBKO_02807 6.95e-262 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
IAJLEBKO_02808 1.41e-243 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
IAJLEBKO_02809 5.47e-259 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
IAJLEBKO_02810 4.97e-248 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
IAJLEBKO_02811 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IAJLEBKO_02812 7.83e-140 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
IAJLEBKO_02813 6.24e-76 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
IAJLEBKO_02814 2.61e-280 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
IAJLEBKO_02815 3.71e-236 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
IAJLEBKO_02816 4.01e-44 yvfG - - S - - - YvfG protein
IAJLEBKO_02817 5.15e-306 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
IAJLEBKO_02818 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
IAJLEBKO_02819 3.62e-155 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
IAJLEBKO_02820 8.05e-278 - - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IAJLEBKO_02821 2.14e-173 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
IAJLEBKO_02822 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
IAJLEBKO_02823 9.73e-171 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
IAJLEBKO_02824 1.6e-289 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
IAJLEBKO_02825 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
IAJLEBKO_02826 1.82e-193 gntR - - K - - - RpiR family transcriptional regulator
IAJLEBKO_02828 9.5e-275 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
IAJLEBKO_02829 2.13e-202 yvbV - - EG - - - EamA-like transporter family
IAJLEBKO_02830 1.51e-200 yvbU - - K - - - Transcriptional regulator
IAJLEBKO_02832 7.57e-243 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAJLEBKO_02833 1.11e-260 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
IAJLEBKO_02834 0.0 araE - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IAJLEBKO_02836 2.95e-240 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
IAJLEBKO_02837 2.83e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IAJLEBKO_02838 3.98e-277 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
IAJLEBKO_02839 2.58e-177 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IAJLEBKO_02840 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
IAJLEBKO_02841 9.69e-310 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IAJLEBKO_02843 2.45e-252 lcnDR2 - - V - - - Lanthionine synthetase C-like protein
IAJLEBKO_02845 5.67e-225 lcnDR2 - - V - - - Lanthionine synthetase C-like protein
IAJLEBKO_02846 3.19e-239 lanT - - V ko:K06148,ko:K13409,ko:K20344,ko:K20386 ko02010,ko02024,ko04626,map02010,map02024,map04626 ko00000,ko00001,ko00002,ko02000,ko02044 Peptidase C39 family
IAJLEBKO_02849 4.52e-106 yvbK - - K - - - acetyltransferase
IAJLEBKO_02850 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
IAJLEBKO_02851 1.21e-153 yvbI - - M - - - Membrane
IAJLEBKO_02852 4.44e-134 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
IAJLEBKO_02853 2.38e-128 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
IAJLEBKO_02854 5.16e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
IAJLEBKO_02855 1.61e-144 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
IAJLEBKO_02856 3.25e-222 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IAJLEBKO_02857 5.95e-139 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
IAJLEBKO_02858 3.42e-124 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
IAJLEBKO_02859 3.73e-264 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
IAJLEBKO_02860 3.4e-146 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
IAJLEBKO_02861 7.34e-219 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IAJLEBKO_02862 1.21e-143 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
IAJLEBKO_02863 3.64e-160 spaF - - V ko:K01990,ko:K20459,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
IAJLEBKO_02864 5.48e-154 spaE - - S ko:K20491 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
IAJLEBKO_02865 5.53e-167 spaG - - S ko:K20492 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
IAJLEBKO_02866 1.29e-156 spaR - - K ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
IAJLEBKO_02867 0.0 spaK 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
IAJLEBKO_02868 2.97e-70 yvaP - - K - - - transcriptional
IAJLEBKO_02869 3.52e-96 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
IAJLEBKO_02870 2.73e-92 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
IAJLEBKO_02871 1.64e-47 yvzC - - K - - - transcriptional
IAJLEBKO_02872 4.58e-36 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
IAJLEBKO_02873 6.92e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
IAJLEBKO_02874 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IAJLEBKO_02875 4.85e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IAJLEBKO_02877 1.2e-71 - - - - - - - -
IAJLEBKO_02878 6.38e-61 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
IAJLEBKO_02879 2.77e-180 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
IAJLEBKO_02880 3.41e-207 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
IAJLEBKO_02881 1.29e-129 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
IAJLEBKO_02882 2.3e-165 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
IAJLEBKO_02883 7.14e-188 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
IAJLEBKO_02884 3.46e-155 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IAJLEBKO_02885 2.36e-155 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IAJLEBKO_02886 1.49e-179 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
IAJLEBKO_02887 3.04e-233 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAJLEBKO_02888 1.01e-61 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
IAJLEBKO_02889 0.0 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAJLEBKO_02890 1.43e-153 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IAJLEBKO_02891 7.9e-246 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
IAJLEBKO_02892 2.81e-64 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
IAJLEBKO_02893 3.24e-40 - - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Heavy-metal-associated domain
IAJLEBKO_02894 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
IAJLEBKO_02895 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
IAJLEBKO_02896 8.75e-136 bdbD - - O - - - Thioredoxin
IAJLEBKO_02897 3.05e-95 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
IAJLEBKO_02898 1.34e-190 - - - S - - - Metallo-peptidase family M12
IAJLEBKO_02899 2.48e-127 yvgT - - S - - - membrane
IAJLEBKO_02900 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
IAJLEBKO_02901 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IAJLEBKO_02902 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
IAJLEBKO_02903 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
IAJLEBKO_02904 1.32e-111 yvgO - - - - - - -
IAJLEBKO_02905 1.77e-200 yvgN - - S - - - reductase
IAJLEBKO_02906 1.49e-254 sagI - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
IAJLEBKO_02907 1.36e-246 sagH - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
IAJLEBKO_02908 1.94e-217 sagG - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
IAJLEBKO_02909 4.77e-250 - - - T - - - Histidine kinase
IAJLEBKO_02910 5.32e-147 yfiK - - K - - - Regulator
IAJLEBKO_02911 5.72e-127 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
IAJLEBKO_02912 1.13e-177 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
IAJLEBKO_02913 1.11e-210 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
IAJLEBKO_02914 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
IAJLEBKO_02915 1.01e-110 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
IAJLEBKO_02916 4.34e-19 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
IAJLEBKO_02917 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
IAJLEBKO_02918 5.06e-159 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IAJLEBKO_02919 2.59e-227 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IAJLEBKO_02920 1.56e-236 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAJLEBKO_02921 4.58e-224 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAJLEBKO_02922 1.02e-188 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
IAJLEBKO_02923 8.03e-87 yvrL - - S - - - Regulatory protein YrvL
IAJLEBKO_02924 2.1e-293 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
IAJLEBKO_02925 1.88e-21 - - - S - - - YvrJ protein family
IAJLEBKO_02926 1.31e-133 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
IAJLEBKO_02927 1.67e-50 - - - - - - - -
IAJLEBKO_02928 2.7e-172 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IAJLEBKO_02929 0.0 yvrG - - T - - - Histidine kinase
IAJLEBKO_02930 3.11e-218 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
IAJLEBKO_02931 7.09e-180 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
IAJLEBKO_02932 6.72e-215 yvrC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
IAJLEBKO_02933 2.55e-227 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAJLEBKO_02934 5.27e-280 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
IAJLEBKO_02935 1.87e-132 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
IAJLEBKO_02936 1.95e-289 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
IAJLEBKO_02937 6.33e-66 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
IAJLEBKO_02938 3.63e-129 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
IAJLEBKO_02939 5.11e-186 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
IAJLEBKO_02940 1.27e-163 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
IAJLEBKO_02941 3.48e-247 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IAJLEBKO_02942 8.35e-139 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IAJLEBKO_02943 1.07e-262 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
IAJLEBKO_02944 2.07e-242 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
IAJLEBKO_02945 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
IAJLEBKO_02946 1.83e-33 - - - S - - - Protein of unknown function (DUF3970)
IAJLEBKO_02947 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IAJLEBKO_02948 7.31e-200 yuxN - - K - - - Transcriptional regulator
IAJLEBKO_02949 4.63e-33 - - - - - - - -
IAJLEBKO_02950 0.0 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IAJLEBKO_02951 3.17e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IAJLEBKO_02952 4.4e-304 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IAJLEBKO_02953 1.18e-102 dps2 - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
IAJLEBKO_02954 2.91e-192 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
IAJLEBKO_02955 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
IAJLEBKO_02956 7.61e-60 - - - S - - - YusW-like protein
IAJLEBKO_02957 5.24e-192 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
IAJLEBKO_02958 2.15e-52 yusU - - S - - - Protein of unknown function (DUF2573)
IAJLEBKO_02959 6.38e-236 apbA 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IAJLEBKO_02960 5.88e-176 - 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
IAJLEBKO_02961 5.44e-200 - - - K - - - Transcriptional regulator
IAJLEBKO_02962 0.0 yusP - - P - - - Major facilitator superfamily
IAJLEBKO_02963 9.65e-92 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
IAJLEBKO_02964 4.46e-72 yusN - - M - - - Coat F domain
IAJLEBKO_02965 6.46e-58 - - - - - - - -
IAJLEBKO_02966 3.46e-211 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
IAJLEBKO_02967 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
IAJLEBKO_02968 7.74e-278 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
IAJLEBKO_02969 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
IAJLEBKO_02970 7.13e-84 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
IAJLEBKO_02971 4.16e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
IAJLEBKO_02972 3.1e-55 yusG - - S - - - Protein of unknown function (DUF2553)
IAJLEBKO_02973 2.17e-82 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
IAJLEBKO_02974 1.64e-72 yusE - - CO - - - Thioredoxin
IAJLEBKO_02975 5.28e-76 yusD - - S - - - SCP-2 sterol transfer family
IAJLEBKO_02976 3.71e-237 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IAJLEBKO_02977 2.08e-138 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
IAJLEBKO_02978 9e-187 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
IAJLEBKO_02979 2.54e-84 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IAJLEBKO_02980 3.82e-183 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
IAJLEBKO_02981 5.01e-311 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
IAJLEBKO_02982 2.31e-298 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IAJLEBKO_02983 8.89e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
IAJLEBKO_02984 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
IAJLEBKO_02985 1.25e-201 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
IAJLEBKO_02986 1.44e-256 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
IAJLEBKO_02987 3.33e-85 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
IAJLEBKO_02989 2.73e-211 - - - K - - - helix_turn_helix, mercury resistance
IAJLEBKO_02990 2.23e-75 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
IAJLEBKO_02991 1.28e-313 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
IAJLEBKO_02992 1.51e-202 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IAJLEBKO_02993 8.84e-210 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
IAJLEBKO_02994 1.78e-204 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
IAJLEBKO_02995 2.4e-172 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
IAJLEBKO_02996 7.51e-262 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IAJLEBKO_02997 5.35e-213 bsn - - L - - - Ribonuclease
IAJLEBKO_02998 1.9e-296 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
IAJLEBKO_02999 1.99e-300 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
IAJLEBKO_03000 1.23e-273 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
IAJLEBKO_03004 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
IAJLEBKO_03005 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
IAJLEBKO_03006 1.45e-78 - - - S - - - phosphoglycolate phosphatase activity
IAJLEBKO_03007 6.03e-216 yunF - - S - - - Protein of unknown function DUF72
IAJLEBKO_03008 4.99e-185 yunE - - S ko:K07090 - ko00000 membrane transporter protein
IAJLEBKO_03009 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
IAJLEBKO_03010 7.89e-167 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
IAJLEBKO_03011 2.36e-250 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
IAJLEBKO_03012 3.92e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IAJLEBKO_03013 3.71e-62 yutD - - S - - - protein conserved in bacteria
IAJLEBKO_03014 3e-93 yutE - - S - - - Protein of unknown function DUF86
IAJLEBKO_03015 2.39e-179 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IAJLEBKO_03016 1.5e-109 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
IAJLEBKO_03017 4.25e-248 yutH - - S - - - Spore coat protein
IAJLEBKO_03018 1.43e-308 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
IAJLEBKO_03019 2.3e-251 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IAJLEBKO_03020 1.12e-215 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IAJLEBKO_03021 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
IAJLEBKO_03022 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
IAJLEBKO_03023 4.5e-71 yuzD - - S - - - protein conserved in bacteria
IAJLEBKO_03024 1.71e-265 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
IAJLEBKO_03025 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
IAJLEBKO_03026 4.26e-273 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IAJLEBKO_03027 3.2e-207 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IAJLEBKO_03028 1.38e-82 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
IAJLEBKO_03029 4.28e-176 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
IAJLEBKO_03030 3.36e-35 - - - K - - - helix_turn_helix, mercury resistance
IAJLEBKO_03032 2.63e-44 - - - S - - - Bacteriocin class IId cyclical uberolysin-like
IAJLEBKO_03034 1.08e-155 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
IAJLEBKO_03035 1.63e-90 - - - CP - - - Membrane
IAJLEBKO_03036 5.68e-40 - - - - - - - -
IAJLEBKO_03037 4.51e-235 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IAJLEBKO_03039 1.03e-238 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
IAJLEBKO_03040 4.16e-301 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
IAJLEBKO_03041 8.54e-46 yuiB - - S - - - Putative membrane protein
IAJLEBKO_03042 2.42e-153 yuiC - - S - - - protein conserved in bacteria
IAJLEBKO_03043 7.09e-101 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
IAJLEBKO_03044 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IAJLEBKO_03045 9.54e-275 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
IAJLEBKO_03046 8.78e-130 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
IAJLEBKO_03047 4.59e-155 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
IAJLEBKO_03048 4.05e-208 eSD - - S ko:K07017 - ko00000 Putative esterase
IAJLEBKO_03049 6.79e-169 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
IAJLEBKO_03050 2.94e-281 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
IAJLEBKO_03051 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
IAJLEBKO_03052 1.87e-218 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
IAJLEBKO_03053 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IAJLEBKO_03054 2.24e-45 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
IAJLEBKO_03055 1.7e-168 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
IAJLEBKO_03056 6.65e-260 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
IAJLEBKO_03057 2.11e-291 yukF - - QT - - - Transcriptional regulator
IAJLEBKO_03058 5.85e-169 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IAJLEBKO_03059 2.23e-124 yueE - - S ko:K06950 - ko00000 phosphohydrolase
IAJLEBKO_03060 1.98e-31 - - - S - - - Protein of unknown function (DUF2642)
IAJLEBKO_03061 1.54e-237 yueF - - S - - - transporter activity
IAJLEBKO_03062 9e-46 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
IAJLEBKO_03063 5.46e-51 yueH - - S - - - YueH-like protein
IAJLEBKO_03064 7.94e-90 yueI - - S - - - Protein of unknown function (DUF1694)
IAJLEBKO_03065 8.02e-135 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
IAJLEBKO_03066 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IAJLEBKO_03067 6.32e-294 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
IAJLEBKO_03068 1.72e-66 yuzC - - - - - - -
IAJLEBKO_03070 2.66e-11 - - - S - - - DegQ (SacQ) family
IAJLEBKO_03071 5.19e-117 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Polyprenyl synthetase
IAJLEBKO_03073 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IAJLEBKO_03074 8.07e-148 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IAJLEBKO_03075 9.44e-82 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
IAJLEBKO_03076 4.2e-79 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
IAJLEBKO_03077 1.1e-51 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IAJLEBKO_03078 9.67e-99 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IAJLEBKO_03079 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IAJLEBKO_03080 1.47e-67 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IAJLEBKO_03081 1.27e-89 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IAJLEBKO_03082 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
IAJLEBKO_03084 4.39e-218 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
IAJLEBKO_03085 3.86e-238 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
IAJLEBKO_03086 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
IAJLEBKO_03087 2.36e-248 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
IAJLEBKO_03088 5.63e-163 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
IAJLEBKO_03089 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
IAJLEBKO_03090 1.6e-101 yufK - - S - - - Family of unknown function (DUF5366)
IAJLEBKO_03091 2.62e-95 yuxK - - S - - - protein conserved in bacteria
IAJLEBKO_03092 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
IAJLEBKO_03093 2.25e-264 yuxJ - - EGP - - - Major facilitator superfamily
IAJLEBKO_03094 2.64e-153 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
IAJLEBKO_03095 3.28e-87 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
IAJLEBKO_03096 8.61e-291 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IAJLEBKO_03097 6.16e-282 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
IAJLEBKO_03098 1.73e-54 yugE - - S - - - Domain of unknown function (DUF1871)
IAJLEBKO_03099 4.71e-199 yugF - - I - - - Hydrolase
IAJLEBKO_03100 3.75e-109 alaR - - K - - - Transcriptional regulator
IAJLEBKO_03101 6.82e-266 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
IAJLEBKO_03102 1.43e-82 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
IAJLEBKO_03103 3.14e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
IAJLEBKO_03104 9.52e-286 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
IAJLEBKO_03105 6.49e-290 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
IAJLEBKO_03106 2.51e-151 ycaC - - Q - - - Isochorismatase family
IAJLEBKO_03107 1.38e-51 - - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
IAJLEBKO_03108 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
IAJLEBKO_03110 1.17e-92 yugN - - S - - - YugN-like family
IAJLEBKO_03111 2.8e-230 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
IAJLEBKO_03112 3.47e-35 mstX - - S - - - Membrane-integrating protein Mistic
IAJLEBKO_03113 3.06e-23 - - - - - - - -
IAJLEBKO_03114 1.67e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
IAJLEBKO_03115 4.67e-296 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
IAJLEBKO_03116 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
IAJLEBKO_03117 7.42e-96 yugU - - S - - - Uncharacterised protein family UPF0047
IAJLEBKO_03118 1.41e-242 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
IAJLEBKO_03119 9.36e-55 - - - - - - - -
IAJLEBKO_03120 6.36e-179 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
IAJLEBKO_03121 4.4e-316 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IAJLEBKO_03122 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IAJLEBKO_03123 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IAJLEBKO_03124 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IAJLEBKO_03125 5.71e-126 yraA 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 DJ-1/PfpI family
IAJLEBKO_03126 2.24e-236 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
IAJLEBKO_03127 4.05e-250 yubA - - S - - - transporter activity
IAJLEBKO_03128 6.56e-187 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
IAJLEBKO_03132 4.26e-19 - - - - - - - -
IAJLEBKO_03134 1.43e-175 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Aspartate phosphatase response regulator
IAJLEBKO_03138 3.74e-69 yjcN - - - - - - -
IAJLEBKO_03139 8.44e-154 - - - G - - - Cupin
IAJLEBKO_03140 2.15e-280 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IAJLEBKO_03141 8.63e-190 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IAJLEBKO_03142 1.76e-155 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
IAJLEBKO_03143 3.37e-121 yuaB - - - - - - -
IAJLEBKO_03144 1.67e-123 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
IAJLEBKO_03145 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
IAJLEBKO_03146 1.74e-290 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
IAJLEBKO_03147 6.79e-141 - - - S - - - MOSC domain
IAJLEBKO_03148 1.66e-101 yuaE - - S - - - DinB superfamily
IAJLEBKO_03149 5.61e-109 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
IAJLEBKO_03150 3.08e-277 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
IAJLEBKO_03151 1.99e-124 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
IAJLEBKO_03154 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
IAJLEBKO_03155 1.87e-307 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
IAJLEBKO_03156 4.9e-76 yflT - - S - - - Heat induced stress protein YflT
IAJLEBKO_03157 2.1e-31 - - - S - - - Protein of unknown function (DUF3212)
IAJLEBKO_03158 1.35e-238 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
IAJLEBKO_03159 2.7e-82 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
IAJLEBKO_03160 4.02e-261 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
IAJLEBKO_03161 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IAJLEBKO_03162 1.39e-261 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
IAJLEBKO_03163 8.7e-91 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
IAJLEBKO_03164 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IAJLEBKO_03165 2.43e-265 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
IAJLEBKO_03166 3.48e-214 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
IAJLEBKO_03167 2.04e-162 yfmS - - NT - - - chemotaxis protein
IAJLEBKO_03168 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IAJLEBKO_03169 2.4e-312 yfnA - - E ko:K03294 - ko00000 amino acid
IAJLEBKO_03170 6.35e-277 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
IAJLEBKO_03171 8.13e-238 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
IAJLEBKO_03172 2.22e-279 yfnE - - S - - - Glycosyltransferase like family 2
IAJLEBKO_03173 6.61e-230 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
IAJLEBKO_03174 3.93e-219 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
IAJLEBKO_03175 1.02e-188 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
IAJLEBKO_03176 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
IAJLEBKO_03177 1.27e-185 - 2.1.1.163, 2.1.1.201 - Q ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 methyltransferase
IAJLEBKO_03178 1.68e-146 - - - S - - - CAAX protease self-immunity
IAJLEBKO_03179 1.29e-194 - - - C - - - Nitroreductase family
IAJLEBKO_03180 0.0 - - - S ko:K09136 - ko00000,ko03009 YcaO cyclodehydratase, ATP-ad Mg2+-binding
IAJLEBKO_03181 2.06e-233 - - - S - - - ATP diphosphatase activity
IAJLEBKO_03182 5.22e-163 - - - - - - - -
IAJLEBKO_03183 4.52e-100 - - - S - - - protein homooligomerization
IAJLEBKO_03184 7.58e-162 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
IAJLEBKO_03185 5.72e-207 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
IAJLEBKO_03186 5.83e-67 - - - K - - - Winged helix DNA-binding domain
IAJLEBKO_03188 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
IAJLEBKO_03189 2.38e-252 yetN - - S - - - Protein of unknown function (DUF3900)
IAJLEBKO_03190 3.88e-261 yetM - - CH - - - FAD binding domain
IAJLEBKO_03191 1.92e-113 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
IAJLEBKO_03192 7.32e-135 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
IAJLEBKO_03193 3.68e-73 - - - H - - - riboflavin kinase activity
IAJLEBKO_03194 1.34e-31 - - - S - - - Uncharacterized small protein (DUF2292)
IAJLEBKO_03195 6.02e-195 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IAJLEBKO_03196 2.66e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IAJLEBKO_03197 1.11e-72 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
IAJLEBKO_03198 2.12e-155 yetF - - S - - - membrane
IAJLEBKO_03199 0.000118 - - - - - - - -
IAJLEBKO_03200 4.48e-120 yesJ - - K - - - Acetyltransferase (GNAT) family
IAJLEBKO_03201 1.48e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
IAJLEBKO_03202 1.62e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
IAJLEBKO_03203 2.67e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
IAJLEBKO_03204 9.27e-137 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
IAJLEBKO_03206 3.12e-162 yeeN - - K - - - transcriptional regulatory protein
IAJLEBKO_03207 1.43e-67 - - - S - - - Protein of unknown function, DUF600
IAJLEBKO_03208 1.62e-78 - - - S - - - Protein of unknown function, DUF600
IAJLEBKO_03209 1.37e-175 cylB - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
IAJLEBKO_03210 9.62e-203 cylA - - V ko:K01990,ko:K09695,ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
IAJLEBKO_03211 5.22e-144 - 1.1.1.100 - IQ ko:K00059,ko:K07535 ko00061,ko00333,ko00362,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,ko01220,map00061,map00333,map00362,map00780,map01040,map01100,map01120,map01130,map01212,map01220 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
IAJLEBKO_03212 1.01e-168 - 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 3-oxoacyl-[acyl-carrier-protein] synthase activity
IAJLEBKO_03213 1.25e-246 - 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IAJLEBKO_03214 4.7e-82 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IAJLEBKO_03215 1.27e-44 - - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
IAJLEBKO_03217 8.44e-102 vraR - - KT ko:K07694,ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IAJLEBKO_03218 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IAJLEBKO_03219 5.16e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IAJLEBKO_03220 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IAJLEBKO_03221 5.24e-196 yerO - - K - - - Transcriptional regulator
IAJLEBKO_03222 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IAJLEBKO_03223 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IAJLEBKO_03224 1.81e-60 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IAJLEBKO_03225 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IAJLEBKO_03226 1.68e-157 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
IAJLEBKO_03227 3.34e-244 yerI - - S - - - homoserine kinase type II (protein kinase fold)
IAJLEBKO_03228 6.46e-285 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
IAJLEBKO_03229 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IAJLEBKO_03230 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
IAJLEBKO_03231 8.71e-164 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
IAJLEBKO_03232 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
IAJLEBKO_03233 2.03e-67 yerC - - S - - - protein conserved in bacteria
IAJLEBKO_03234 6.02e-247 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
IAJLEBKO_03235 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
IAJLEBKO_03236 1.2e-33 - - - S - - - Protein of unknown function (DUF2892)
IAJLEBKO_03237 3.29e-297 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
IAJLEBKO_03238 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
IAJLEBKO_03239 9.96e-135 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IAJLEBKO_03240 1.46e-241 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
IAJLEBKO_03241 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IAJLEBKO_03242 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IAJLEBKO_03243 9.46e-167 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IAJLEBKO_03244 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IAJLEBKO_03245 3.96e-165 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
IAJLEBKO_03246 6.38e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IAJLEBKO_03247 3.74e-286 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IAJLEBKO_03248 3.78e-107 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IAJLEBKO_03249 6.56e-40 yebG - - S - - - NETI protein
IAJLEBKO_03250 1.21e-118 yebE - - S - - - UPF0316 protein
IAJLEBKO_03252 6.19e-168 yebC - - M - - - Membrane
IAJLEBKO_03253 1.75e-269 pbuG - - S ko:K06901 - ko00000,ko02000 permease
IAJLEBKO_03254 1.51e-313 - - - S - - - Domain of unknown function (DUF4179)
IAJLEBKO_03255 1.34e-121 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IAJLEBKO_03256 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
IAJLEBKO_03257 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
IAJLEBKO_03258 7.2e-265 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
IAJLEBKO_03259 2.29e-225 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
IAJLEBKO_03260 4.33e-315 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
IAJLEBKO_03261 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
IAJLEBKO_03262 2.02e-47 ydjO - - S - - - Cold-inducible protein YdjO
IAJLEBKO_03264 1.36e-192 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
IAJLEBKO_03265 6.51e-82 ydjM - - M - - - Lytic transglycolase
IAJLEBKO_03266 8.25e-248 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
IAJLEBKO_03267 1.87e-113 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IAJLEBKO_03268 4.82e-194 rsiV - - S - - - Protein of unknown function (DUF3298)
IAJLEBKO_03269 0.0 oatA - - I - - - Acyltransferase family
IAJLEBKO_03270 2.8e-201 ydjI - - S - - - virion core protein (lumpy skin disease virus)
IAJLEBKO_03271 8.73e-160 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
IAJLEBKO_03272 1.55e-229 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IAJLEBKO_03273 3.9e-146 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
IAJLEBKO_03274 1.47e-40 yjdJ - - S - - - Domain of unknown function (DUF4306)
IAJLEBKO_03275 1.42e-219 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
IAJLEBKO_03276 1.18e-315 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
IAJLEBKO_03277 2.05e-256 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
IAJLEBKO_03278 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
IAJLEBKO_03279 7.07e-51 - - - S - - - Protein of unknown function (DUF4064)
IAJLEBKO_03280 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IAJLEBKO_03281 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IAJLEBKO_03282 1.67e-164 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
IAJLEBKO_03283 1.11e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
IAJLEBKO_03284 1.92e-161 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IAJLEBKO_03285 1.72e-29 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
IAJLEBKO_03286 1.29e-149 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IAJLEBKO_03287 2.95e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
IAJLEBKO_03288 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
IAJLEBKO_03289 1.26e-242 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IAJLEBKO_03290 1.41e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
IAJLEBKO_03291 2.8e-160 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
IAJLEBKO_03292 7.42e-112 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
IAJLEBKO_03293 4.87e-234 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IAJLEBKO_03295 6.72e-55 ydbB - - G - - - Cupin domain
IAJLEBKO_03296 2.39e-78 ydbC - - S - - - Domain of unknown function (DUF4937
IAJLEBKO_03297 7.8e-198 ydbD - - P ko:K07217 - ko00000 Catalase
IAJLEBKO_03298 4.46e-254 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
IAJLEBKO_03299 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
IAJLEBKO_03300 3.67e-153 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
IAJLEBKO_03301 1.12e-286 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IAJLEBKO_03302 1.22e-230 ydbI - - S - - - AI-2E family transporter
IAJLEBKO_03303 7.61e-218 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IAJLEBKO_03304 9.93e-167 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IAJLEBKO_03305 1.32e-69 ydbL - - - - - - -
IAJLEBKO_03306 2.98e-260 ydbM - - I - - - acyl-CoA dehydrogenase
IAJLEBKO_03307 1.13e-15 - - - S - - - Fur-regulated basic protein B
IAJLEBKO_03308 6.58e-14 - - - S - - - Fur-regulated basic protein A
IAJLEBKO_03309 1.91e-158 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IAJLEBKO_03310 2.25e-74 ydbP - - CO - - - Thioredoxin
IAJLEBKO_03311 2.52e-257 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
IAJLEBKO_03312 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IAJLEBKO_03313 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IAJLEBKO_03314 2.18e-96 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
IAJLEBKO_03315 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
IAJLEBKO_03316 2.08e-138 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
IAJLEBKO_03317 1.54e-75 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IAJLEBKO_03318 6.39e-235 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
IAJLEBKO_03319 1.63e-278 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IAJLEBKO_03320 6.68e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
IAJLEBKO_03321 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
IAJLEBKO_03322 1.05e-186 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
IAJLEBKO_03323 1.09e-75 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
IAJLEBKO_03324 1.73e-89 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
IAJLEBKO_03325 1.78e-241 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
IAJLEBKO_03326 9.77e-71 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
IAJLEBKO_03327 5.84e-110 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
IAJLEBKO_03328 1.14e-180 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IAJLEBKO_03329 2.74e-139 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
IAJLEBKO_03330 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
IAJLEBKO_03331 1.78e-21 - - - - - - - -
IAJLEBKO_03332 1.74e-75 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
IAJLEBKO_03340 7.8e-124 yrkL - - S ko:K11748 - ko00000,ko02000 Flavodoxin-like fold
IAJLEBKO_03341 1.14e-190 - - - S - - - Serine aminopeptidase, S33
IAJLEBKO_03342 0.0 - - - EGP ko:K03761,ko:K03762 - ko00000,ko02000 Transporter
IAJLEBKO_03343 3.7e-174 - - - I ko:K01066 - ko00000,ko01000 esterase
IAJLEBKO_03344 3.38e-60 ohrB - - O - - - OsmC-like protein
IAJLEBKO_03345 3.16e-64 ohrR - - K - - - Transcriptional regulator
IAJLEBKO_03346 4.42e-84 ywnA - - K - - - Transcriptional regulator
IAJLEBKO_03347 5.24e-143 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
IAJLEBKO_03348 3.87e-42 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
IAJLEBKO_03349 2.63e-53 yrkD - - S - - - protein conserved in bacteria
IAJLEBKO_03350 1.38e-108 yrkE - - O - - - DsrE/DsrF/DrsH-like family
IAJLEBKO_03351 9.11e-24 - - - P - - - Rhodanese Homology Domain
IAJLEBKO_03352 1.8e-129 yrkF - - OP - - - Belongs to the sulfur carrier protein TusA family
IAJLEBKO_03353 1.23e-255 yrkH - - P - - - Rhodanese Homology Domain
IAJLEBKO_03354 6.46e-49 yrkI - - O - - - Belongs to the sulfur carrier protein TusA family
IAJLEBKO_03355 2.82e-163 yrkJ - - S ko:K07090 - ko00000 membrane transporter protein
IAJLEBKO_03356 1.27e-150 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
IAJLEBKO_03357 8.25e-131 - - - S - - - Protein of unknown function (DUF2812)
IAJLEBKO_03358 7.89e-66 - - - K - - - Transcriptional regulator PadR-like family
IAJLEBKO_03359 2.92e-231 - - - S - - - Patatin-like phospholipase
IAJLEBKO_03360 5.87e-109 - - - S - - - DinB superfamily
IAJLEBKO_03361 1.58e-144 dpaL 4.3.1.15 - E ko:K01751 - ko00000,ko01000 Pyridoxal-phosphate dependent enzyme
IAJLEBKO_03362 6.58e-86 - - - K - - - COG1802 Transcriptional regulators
IAJLEBKO_03363 4.46e-52 - - - J - - - Endoribonuclease L-PSP
IAJLEBKO_03364 8.01e-177 - - - E ko:K03837 - ko00000,ko02000 Serine transporter
IAJLEBKO_03365 2.48e-205 - - - E - - - Peptidase dimerisation domain
IAJLEBKO_03366 2.32e-160 - - - K - - - helix_turn_helix, arabinose operon control protein
IAJLEBKO_03367 6.65e-220 - 3.5.1.6, 3.5.1.87 - E ko:K06016 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
IAJLEBKO_03368 1.01e-295 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IAJLEBKO_03369 1.25e-241 ydeG - - EGP - - - Major facilitator superfamily
IAJLEBKO_03370 6.45e-38 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
IAJLEBKO_03373 0.0 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
IAJLEBKO_03374 1.36e-216 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
IAJLEBKO_03375 2.66e-248 trkA - - P ko:K07222 - ko00000 Oxidoreductase
IAJLEBKO_03378 1.3e-08 ykkA - - S - - - Protein of unknown function (DUF664)
IAJLEBKO_03379 5.69e-191 dapA7 4.3.3.7 - EM ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Dihydrodipicolinate synthetase family
IAJLEBKO_03381 1.09e-249 cfr 2.1.1.224 - J ko:K15632 - ko00000,ko01000,ko01504,ko03009 Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
IAJLEBKO_03382 2.4e-68 ydeH - - - - - - -
IAJLEBKO_03383 8.41e-212 - - - S - - - Sodium Bile acid symporter family
IAJLEBKO_03384 1.06e-256 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
IAJLEBKO_03385 1.21e-85 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
IAJLEBKO_03386 4.37e-285 nhaC_1 - - C - - - antiporter
IAJLEBKO_03387 0.0 - - - K ko:K00375 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
IAJLEBKO_03388 1.03e-146 paiB - - K ko:K07734 - ko00000,ko03000 Transcriptional regulator
IAJLEBKO_03390 5.9e-248 ydeR - - EGP - - - Uncharacterised MFS-type transporter YbfB
IAJLEBKO_03391 4.7e-130 ydeS - - K - - - Transcriptional regulator
IAJLEBKO_03392 3.45e-64 yraD - - M ko:K06439 - ko00000 Spore coat protein
IAJLEBKO_03393 4.86e-33 yraE - - - ko:K06440 - ko00000 -
IAJLEBKO_03394 3.41e-279 adhB 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
IAJLEBKO_03395 4.76e-84 yraF - - M - - - Spore coat protein
IAJLEBKO_03396 9.9e-49 yraG - - - ko:K06440 - ko00000 -
IAJLEBKO_03397 1.72e-275 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IAJLEBKO_03398 3.82e-140 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IAJLEBKO_03399 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
IAJLEBKO_03400 3.98e-170 puuD - - S ko:K07010 - ko00000,ko01002 Peptidase C26
IAJLEBKO_03401 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
IAJLEBKO_03402 5.07e-125 ynaD - - J - - - Acetyltransferase (GNAT) domain
IAJLEBKO_03403 6.07e-192 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
IAJLEBKO_03404 6.59e-249 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
IAJLEBKO_03405 3.34e-269 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
IAJLEBKO_03406 3.22e-287 fabF_1 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IAJLEBKO_03407 1.84e-199 - - - K - - - Helix-turn-helix XRE-family like proteins
IAJLEBKO_03408 2.03e-154 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
IAJLEBKO_03409 7.23e-107 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
IAJLEBKO_03410 1.39e-191 bltR - - K - - - helix_turn_helix, mercury resistance
IAJLEBKO_03411 5.16e-191 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IAJLEBKO_03412 9.15e-145 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
IAJLEBKO_03413 1.83e-185 - - - Q - - - ubiE/COQ5 methyltransferase family
IAJLEBKO_03414 5.06e-211 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Isocitrate/isopropylmalate dehydrogenase
IAJLEBKO_03415 7.66e-153 ydhC - - K - - - FCD
IAJLEBKO_03416 4.58e-289 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
IAJLEBKO_03419 0.0 pbpE - - V - - - Beta-lactamase
IAJLEBKO_03421 6.11e-128 ydhK - - M - - - Protein of unknown function (DUF1541)
IAJLEBKO_03422 2.24e-247 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
IAJLEBKO_03423 2.4e-170 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
IAJLEBKO_03424 1.09e-152 - - - K ko:K05799 - ko00000,ko03000 FCD
IAJLEBKO_03425 2.04e-275 yycB1 - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
IAJLEBKO_03426 1.48e-65 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
IAJLEBKO_03427 4.48e-67 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
IAJLEBKO_03428 4.95e-134 yvdT_1 - - K - - - Transcriptional regulator
IAJLEBKO_03429 0.0 ybeC - - E - - - amino acid
IAJLEBKO_03430 9.97e-211 ydhU - - P ko:K07217 - ko00000 Catalase
IAJLEBKO_03431 2.7e-110 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
IAJLEBKO_03432 9.46e-236 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
IAJLEBKO_03433 0.0 iolT - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IAJLEBKO_03436 1.59e-212 ygxA - - S - - - Nucleotidyltransferase-like
IAJLEBKO_03437 4.67e-75 ygzB - - S - - - UPF0295 protein
IAJLEBKO_03438 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
IAJLEBKO_03439 1.39e-111 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
IAJLEBKO_03440 2.79e-313 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
IAJLEBKO_03441 5.27e-239 ygaE - - S - - - Membrane
IAJLEBKO_03442 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
IAJLEBKO_03443 2.32e-135 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
IAJLEBKO_03444 1.4e-49 ygaB - - S - - - YgaB-like protein
IAJLEBKO_03445 4.77e-06 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
IAJLEBKO_03446 3.81e-173 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IAJLEBKO_03447 1.47e-49 yfhS - - - - - - -
IAJLEBKO_03448 1.64e-261 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
IAJLEBKO_03449 1.25e-235 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
IAJLEBKO_03450 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
IAJLEBKO_03451 1.35e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
IAJLEBKO_03452 2.28e-217 - - - S - - - Alpha/beta hydrolase family
IAJLEBKO_03453 9.59e-54 yfhL - - S - - - SdpI/YhfL protein family
IAJLEBKO_03454 4.68e-121 yfhK - - T - - - Bacterial SH3 domain homologues
IAJLEBKO_03455 2.57e-59 yfhJ - - S - - - WVELL protein
IAJLEBKO_03456 2.02e-215 mpr - - M - - - Belongs to the peptidase S1B family
IAJLEBKO_03458 2.25e-265 yfhI - - EGP - - - -transporter
IAJLEBKO_03459 3.1e-69 yfhH - - S - - - Protein of unknown function (DUF1811)
IAJLEBKO_03460 5.21e-182 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
IAJLEBKO_03461 2.01e-213 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
IAJLEBKO_03463 3.61e-34 yfhD - - S - - - YfhD-like protein
IAJLEBKO_03464 4.76e-137 yfhC - - C - - - nitroreductase
IAJLEBKO_03465 6.68e-205 yfhB - - S - - - PhzF family
IAJLEBKO_03466 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IAJLEBKO_03467 2.29e-107 yfiV - - K - - - transcriptional
IAJLEBKO_03468 0.0 yfiU - - EGP - - - the major facilitator superfamily
IAJLEBKO_03469 1.82e-125 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
IAJLEBKO_03470 1.66e-60 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
IAJLEBKO_03471 0.0 - 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
IAJLEBKO_03472 3.49e-232 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
IAJLEBKO_03473 3.47e-142 - 1.6.5.2 - S ko:K00355 ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
IAJLEBKO_03474 9.33e-125 padR - - K - - - transcriptional
IAJLEBKO_03475 1.34e-210 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
IAJLEBKO_03476 7.82e-204 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
IAJLEBKO_03477 7.86e-82 yfiD3 - - S - - - DoxX
IAJLEBKO_03478 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
IAJLEBKO_03479 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
IAJLEBKO_03480 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IAJLEBKO_03481 4.47e-178 glvR - - F ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
IAJLEBKO_03482 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
IAJLEBKO_03483 6.64e-22 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
IAJLEBKO_03484 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
IAJLEBKO_03485 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IAJLEBKO_03486 3.79e-272 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IAJLEBKO_03487 5.1e-240 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IAJLEBKO_03488 1.31e-242 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IAJLEBKO_03489 1.76e-112 yfjM - - S - - - Psort location Cytoplasmic, score
IAJLEBKO_03490 4.22e-245 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IAJLEBKO_03491 2.4e-58 - - - S - - - YfzA-like protein
IAJLEBKO_03492 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IAJLEBKO_03493 1.21e-208 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IAJLEBKO_03494 2.61e-235 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
IAJLEBKO_03496 2.98e-188 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
IAJLEBKO_03497 4.36e-199 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
IAJLEBKO_03498 7.99e-37 yfjT - - - - - - -
IAJLEBKO_03499 4.65e-279 yfkA - - S - - - YfkB-like domain
IAJLEBKO_03500 6.79e-185 yfkC - - M - - - Mechanosensitive ion channel
IAJLEBKO_03501 1.33e-184 yfkD - - S - - - YfkD-like protein
IAJLEBKO_03502 1.7e-238 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
IAJLEBKO_03503 5.89e-278 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
IAJLEBKO_03504 6.71e-12 - - - - - - - -
IAJLEBKO_03505 1.6e-184 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
IAJLEBKO_03506 2.14e-69 yfkI - - S - - - gas vesicle protein
IAJLEBKO_03507 6.88e-112 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IAJLEBKO_03508 1.47e-41 yfkK - - S - - - Belongs to the UPF0435 family
IAJLEBKO_03509 3.85e-249 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
IAJLEBKO_03510 2.04e-174 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
IAJLEBKO_03511 1.01e-208 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IAJLEBKO_03512 1.51e-237 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
IAJLEBKO_03513 7.82e-118 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
IAJLEBKO_03514 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
IAJLEBKO_03515 1.22e-252 yibE - - S - - - YibE/F-like protein
IAJLEBKO_03516 2.01e-165 yibF - - S - - - YibE/F-like protein
IAJLEBKO_03517 1.19e-157 frp - - C - - - nitroreductase
IAJLEBKO_03518 3.66e-165 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
IAJLEBKO_03519 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
IAJLEBKO_03520 1.57e-313 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IAJLEBKO_03521 1.85e-53 ydgB - - S - - - Spore germination protein gerPA/gerPF
IAJLEBKO_03522 8.17e-52 ydgA - - S - - - Spore germination protein gerPA/gerPF
IAJLEBKO_03523 8.64e-106 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
IAJLEBKO_03524 4.9e-83 ydhN1 - - S - - - Domain of unknown function (DUF1992)
IAJLEBKO_03525 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
IAJLEBKO_03526 1.17e-96 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
IAJLEBKO_03527 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
IAJLEBKO_03528 1.9e-177 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
IAJLEBKO_03529 1.67e-66 yflH - - S - - - Protein of unknown function (DUF3243)
IAJLEBKO_03530 1.98e-26 yflI - - - - - - -
IAJLEBKO_03531 5.84e-21 yflJ - - S - - - Protein of unknown function (DUF2639)
IAJLEBKO_03532 4.17e-157 yflK - - S - - - protein conserved in bacteria
IAJLEBKO_03533 3.93e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
IAJLEBKO_03534 6.81e-276 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
IAJLEBKO_03535 1.34e-189 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
IAJLEBKO_03536 5.52e-285 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
IAJLEBKO_03537 6.35e-226 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
IAJLEBKO_03538 9.33e-153 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
IAJLEBKO_03539 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
IAJLEBKO_03541 7.54e-07 - - - S - - - domain, Protein
IAJLEBKO_03544 6.02e-57 - - - Q - - - calcium- and calmodulin-responsive adenylate cyclase activity
IAJLEBKO_03545 4.61e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IAJLEBKO_03546 1.54e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IAJLEBKO_03547 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
IAJLEBKO_03548 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IAJLEBKO_03549 7.99e-195 ypaH - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IAJLEBKO_03550 2.31e-195 - - - S - - - Domain of unknown function (DUF5068)
IAJLEBKO_03552 2.95e-211 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
IAJLEBKO_03553 2.64e-86 yybR - - K - - - Transcriptional regulator
IAJLEBKO_03554 2.25e-109 cotF - - M ko:K06329 - ko00000 Spore coat protein
IAJLEBKO_03556 2.48e-204 yybS - - S - - - membrane
IAJLEBKO_03557 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
IAJLEBKO_03558 1.58e-95 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
IAJLEBKO_03559 1.45e-158 - - - KLT - - - COG0515 Serine threonine protein kinase
IAJLEBKO_03560 2.15e-157 - - - S - - - GlcNAc-PI de-N-acetylase
IAJLEBKO_03561 1.18e-308 - - - M - - - Glycosyltransferase Family 4
IAJLEBKO_03562 1.27e-294 - - - S - - - Carbamoyl-phosphate synthase L chain, ATP binding domain
IAJLEBKO_03563 1.75e-256 - - - S - - - Ecdysteroid kinase
IAJLEBKO_03564 3.18e-299 - - - M - - - Glycosyltransferase Family 4
IAJLEBKO_03565 5.12e-25 yycC - - K - - - YycC-like protein
IAJLEBKO_03567 6.11e-36 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
IAJLEBKO_03568 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
IAJLEBKO_03569 1.29e-93 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IAJLEBKO_03570 1.55e-315 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IAJLEBKO_03575 1.51e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IAJLEBKO_03576 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IAJLEBKO_03577 0.0 yycH - - S - - - protein conserved in bacteria
IAJLEBKO_03578 1.98e-194 yycI - - S - - - protein conserved in bacteria
IAJLEBKO_03579 1.98e-191 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
IAJLEBKO_03580 1.1e-276 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IAJLEBKO_03581 9.61e-14 phoP1 - - KT ko:K02483 - ko00000,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IAJLEBKO_03582 8.4e-314 - 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
IAJLEBKO_03583 3.82e-240 thiF 2.7.7.73 - H ko:K03148 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 ThiF family
IAJLEBKO_03584 0.0 - - - - - - - -
IAJLEBKO_03585 1.85e-252 - - - S - - - Major Facilitator Superfamily
IAJLEBKO_03586 0.0 - - - S - - - ABC transporter
IAJLEBKO_03587 7.53e-188 - 1.14.11.27 - P ko:K10277 - ko00000,ko01000,ko03036 peptidyl-arginine hydroxylation
IAJLEBKO_03588 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
IAJLEBKO_03589 2.69e-57 sdpR - - K - - - transcriptional
IAJLEBKO_03590 2.07e-84 yvaZ - - S - - - Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
IAJLEBKO_03591 6.81e-295 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
IAJLEBKO_03592 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
IAJLEBKO_03593 2.64e-212 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
IAJLEBKO_03594 3.7e-259 - - - S ko:K06361,ko:K06365,ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
IAJLEBKO_03596 8.36e-113 yycN - - K - - - Acetyltransferase
IAJLEBKO_03597 1.24e-232 - - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
IAJLEBKO_03598 1.13e-169 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
IAJLEBKO_03599 3.14e-275 yycP - - - - - - -
IAJLEBKO_03602 4.11e-105 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IAJLEBKO_03603 2.12e-17 tnp - - L ko:K07493 - ko00000 transposase activity
IAJLEBKO_03604 2.28e-242 - - - KL - - - HELICc2
IAJLEBKO_03605 1.82e-41 csfB - - S - - - Inhibitor of sigma-G Gin
IAJLEBKO_03606 1.19e-135 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
IAJLEBKO_03607 1.28e-239 yaaN - - P - - - Belongs to the TelA family
IAJLEBKO_03608 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
IAJLEBKO_03609 2.22e-144 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IAJLEBKO_03610 5.03e-73 yaaQ - - S - - - protein conserved in bacteria
IAJLEBKO_03611 2.98e-94 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
IAJLEBKO_03612 2.82e-235 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
IAJLEBKO_03613 9e-189 yaaT - - S - - - stage 0 sporulation protein
IAJLEBKO_03614 3.08e-56 yabA - - L - - - Involved in initiation control of chromosome replication
IAJLEBKO_03615 3.99e-178 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
IAJLEBKO_03616 6.96e-64 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
IAJLEBKO_03617 7.84e-208 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IAJLEBKO_03618 6.14e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
IAJLEBKO_03619 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IAJLEBKO_03620 1.75e-183 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
IAJLEBKO_03621 3.94e-307 yabE - - T - - - protein conserved in bacteria
IAJLEBKO_03622 7.62e-126 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IAJLEBKO_03623 1.19e-202 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IAJLEBKO_03624 5.75e-209 yabG - - S ko:K06436 - ko00000 peptidase
IAJLEBKO_03625 5.32e-53 veg - - S - - - protein conserved in bacteria
IAJLEBKO_03626 7.31e-38 sspF - - S ko:K06423 - ko00000 DNA topological change
IAJLEBKO_03627 7.83e-206 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IAJLEBKO_03628 5.67e-197 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
IAJLEBKO_03629 7.5e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
IAJLEBKO_03630 4.23e-64 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
IAJLEBKO_03631 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IAJLEBKO_03632 2.47e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IAJLEBKO_03633 7.21e-136 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IAJLEBKO_03634 1.74e-136 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IAJLEBKO_03635 1.1e-54 yabK - - S - - - Peptide ABC transporter permease
IAJLEBKO_03636 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IAJLEBKO_03637 8.02e-119 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
IAJLEBKO_03638 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IAJLEBKO_03639 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
IAJLEBKO_03640 1.42e-48 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
IAJLEBKO_03641 5.47e-66 yabP - - S - - - Sporulation protein YabP
IAJLEBKO_03642 9.66e-134 yabQ - - S - - - spore cortex biosynthesis protein
IAJLEBKO_03643 1.2e-74 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
IAJLEBKO_03644 3.54e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
IAJLEBKO_03647 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
IAJLEBKO_03648 3.79e-166 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
IAJLEBKO_03649 1.34e-235 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
IAJLEBKO_03650 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IAJLEBKO_03651 1.05e-119 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
IAJLEBKO_03652 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IAJLEBKO_03653 7.76e-186 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IAJLEBKO_03654 3.19e-206 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IAJLEBKO_03655 1.16e-193 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
IAJLEBKO_03656 7.3e-216 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
IAJLEBKO_03657 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IAJLEBKO_03658 1.79e-137 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
IAJLEBKO_03659 1.64e-205 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
IAJLEBKO_03660 3.06e-201 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IAJLEBKO_03661 1.13e-81 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IAJLEBKO_03662 7.88e-116 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IAJLEBKO_03663 6.1e-40 yazB - - K - - - transcriptional
IAJLEBKO_03664 3.44e-238 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IAJLEBKO_03665 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
IAJLEBKO_03666 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
IAJLEBKO_03667 8.99e-148 - - - K - - - FCD domain
IAJLEBKO_03668 2.74e-117 - - - S - - - PFAM DinB family protein
IAJLEBKO_03669 1.97e-200 - - - G - - - Major Facilitator Superfamily
IAJLEBKO_03670 1.12e-73 ypaA - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
IAJLEBKO_03671 1.7e-148 ydgI - - C - - - nitroreductase
IAJLEBKO_03672 6.79e-90 - - - K - - - Winged helix DNA-binding domain
IAJLEBKO_03673 5.16e-192 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
IAJLEBKO_03674 8.81e-98 yybA - - K - - - transcriptional
IAJLEBKO_03675 1.38e-54 - - - K - - - LysR substrate binding domain
IAJLEBKO_03676 9.36e-124 - - - - - - - -
IAJLEBKO_03677 3.74e-208 - - - M - - - Domain of Unknown Function (DUF1259)
IAJLEBKO_03678 5.27e-78 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
IAJLEBKO_03679 6.64e-208 - - - K - - - Transcriptional regulator
IAJLEBKO_03680 3.89e-175 bdh 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
IAJLEBKO_03681 3.88e-315 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IAJLEBKO_03682 1.73e-164 - - - EG - - - EamA-like transporter family
IAJLEBKO_03683 3.81e-144 - - - K - - - Bacterial transcription activator, effector binding domain
IAJLEBKO_03684 3.3e-127 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
IAJLEBKO_03685 3.45e-30 yyaL - - O ko:K06888 - ko00000 Highly conserved protein containing a thioredoxin domain
IAJLEBKO_03686 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
IAJLEBKO_03687 5.73e-208 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
IAJLEBKO_03688 7.51e-316 - - - G ko:K08369 - ko00000,ko02000 Sugar (and other) transporter
IAJLEBKO_03689 3.43e-88 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IAJLEBKO_03690 6.62e-230 ccpB - - K - - - Transcriptional regulator
IAJLEBKO_03691 1.29e-181 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
IAJLEBKO_03692 1.32e-125 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IAJLEBKO_03693 9.98e-134 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
IAJLEBKO_03694 1.11e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IAJLEBKO_03695 4.77e-99 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IAJLEBKO_03696 2.9e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
IAJLEBKO_03697 5.42e-254 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IAJLEBKO_03698 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IAJLEBKO_03699 1.82e-45 yyzM - - S - - - protein conserved in bacteria
IAJLEBKO_03700 9.63e-225 yyaD - - S - - - Membrane
IAJLEBKO_03701 2.1e-60 yhhY - - K - - - FR47-like protein
IAJLEBKO_03702 4.91e-144 yyaC - - S - - - Sporulation protein YyaC
IAJLEBKO_03703 1.43e-189 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
IAJLEBKO_03704 9.68e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
IAJLEBKO_03705 6.61e-195 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
IAJLEBKO_03706 5.39e-163 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
IAJLEBKO_03707 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IAJLEBKO_03708 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IAJLEBKO_03709 4.45e-140 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
IAJLEBKO_03710 2.12e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IAJLEBKO_03711 1.99e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IAJLEBKO_03712 5.59e-316 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IAJLEBKO_03713 8.12e-262 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IAJLEBKO_03714 3.19e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
IAJLEBKO_03715 7.52e-263 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IAJLEBKO_03716 6.18e-52 yaaB - - S - - - Domain of unknown function (DUF370)
IAJLEBKO_03717 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IAJLEBKO_03718 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IAJLEBKO_03719 2.14e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
IAJLEBKO_03720 1.89e-82 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
IAJLEBKO_03721 1.63e-258 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
IAJLEBKO_03722 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
IAJLEBKO_03723 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IAJLEBKO_03724 8.93e-250 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
IAJLEBKO_03725 8.6e-251 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
IAJLEBKO_03726 1.01e-159 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
IAJLEBKO_03727 3.02e-111 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
IAJLEBKO_03728 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IAJLEBKO_03729 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
IAJLEBKO_03730 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
IAJLEBKO_03731 4.11e-95 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IAJLEBKO_03732 1.01e-172 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IAJLEBKO_03733 4.71e-114 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
IAJLEBKO_03734 1.39e-150 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
IAJLEBKO_03735 3.77e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IAJLEBKO_03736 1.28e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
IAJLEBKO_03737 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IAJLEBKO_03738 8.66e-161 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IAJLEBKO_03739 8.13e-104 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IAJLEBKO_03740 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IAJLEBKO_03741 2.95e-139 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
IAJLEBKO_03742 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IAJLEBKO_03743 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IAJLEBKO_03744 5.94e-46 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
IAJLEBKO_03745 9.47e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IAJLEBKO_03746 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IAJLEBKO_03747 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IAJLEBKO_03748 9.55e-286 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IAJLEBKO_03749 5.06e-234 ybaC - - S - - - Alpha/beta hydrolase family
IAJLEBKO_03750 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
IAJLEBKO_03751 1.02e-143 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IAJLEBKO_03752 2.59e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
IAJLEBKO_03753 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IAJLEBKO_03754 9.5e-201 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IAJLEBKO_03755 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IAJLEBKO_03756 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IAJLEBKO_03757 1.69e-151 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IAJLEBKO_03758 1.38e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IAJLEBKO_03759 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
IAJLEBKO_03760 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IAJLEBKO_03761 1.04e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IAJLEBKO_03762 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IAJLEBKO_03763 5.43e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IAJLEBKO_03764 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IAJLEBKO_03765 1.08e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IAJLEBKO_03766 3.14e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IAJLEBKO_03767 8.29e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IAJLEBKO_03768 4.54e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IAJLEBKO_03769 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
IAJLEBKO_03770 2.1e-94 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
IAJLEBKO_03771 3.15e-295 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IAJLEBKO_03772 4.34e-158 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IAJLEBKO_03773 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IAJLEBKO_03774 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IAJLEBKO_03775 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IAJLEBKO_03776 5.8e-234 yaaC - - S - - - YaaC-like Protein
IAJLEBKO_03777 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
IAJLEBKO_03778 0.0 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
IAJLEBKO_03779 1.29e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
IAJLEBKO_03780 1.17e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
IAJLEBKO_03781 1.85e-284 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IAJLEBKO_03782 1.05e-254 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
IAJLEBKO_03784 2.94e-156 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
IAJLEBKO_03785 2.34e-148 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
IAJLEBKO_03786 2.9e-277 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
IAJLEBKO_03787 1.18e-127 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
IAJLEBKO_03788 1.18e-109 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IAJLEBKO_03789 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IAJLEBKO_03790 6.9e-52 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IAJLEBKO_03791 6e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IAJLEBKO_03792 5.4e-43 yaaL - - S - - - Protein of unknown function (DUF2508)
IAJLEBKO_03793 6.44e-50 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
IAJLEBKO_03794 0.0 - - - Q ko:K15665 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IAJLEBKO_03795 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IAJLEBKO_03796 1.13e-93 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IAJLEBKO_03797 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
IAJLEBKO_03798 3.05e-199 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IAJLEBKO_03799 4.91e-190 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IAJLEBKO_03800 2.77e-178 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IAJLEBKO_03801 1.69e-179 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IAJLEBKO_03802 6.54e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IAJLEBKO_03803 8.64e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
IAJLEBKO_03804 2.92e-184 ybaJ - - Q - - - Methyltransferase domain
IAJLEBKO_03805 7.43e-107 yizA - - S - - - Damage-inducible protein DinB
IAJLEBKO_03806 3.1e-101 ybaK - - S - - - Protein of unknown function (DUF2521)
IAJLEBKO_03807 1.98e-173 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
IAJLEBKO_03808 6.33e-254 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
IAJLEBKO_03809 1.95e-102 gerD - - - ko:K06294 - ko00000 -
IAJLEBKO_03810 1.78e-134 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
IAJLEBKO_03811 5.03e-180 pdaB - - G - - - Polysaccharide deacetylase
IAJLEBKO_03812 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IAJLEBKO_03814 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
IAJLEBKO_03815 5.02e-151 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)