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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HICPPONB_00001	0.0	pacL	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
HICPPONB_00002	1.16e-126	-	-	-	K	-	-	-	Transcriptional regulator
HICPPONB_00003	2.06e-221	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HICPPONB_00004	7.38e-168	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HICPPONB_00005	3.82e-195	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HICPPONB_00006	9.58e-218	ybbR	-	-	S	-	-	-	YbbR-like protein
HICPPONB_00007	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HICPPONB_00008	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HICPPONB_00010	0.0	pepF2	-	-	E	-	-	-	Oligopeptidase F
HICPPONB_00011	3.35e-106	-	-	-	S	-	-	-	VanZ like family
HICPPONB_00012	5.85e-169	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
HICPPONB_00013	1.02e-196	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
HICPPONB_00014	9.23e-218	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
HICPPONB_00015	1e-35	-	-	-	-	ko:K02245	-	ko00000,ko00002,ko02044	-
HICPPONB_00017	3.85e-31	-	-	-	-	-	-	-	-
HICPPONB_00018	1.42e-24	-	-	-	-	ko:K02248	-	ko00000,ko00002,ko02044	-
HICPPONB_00020	4.35e-238	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
HICPPONB_00021	2.1e-81	-	-	-	-	-	-	-	-
HICPPONB_00022	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HICPPONB_00023	2.15e-190	arbV	-	-	I	-	-	-	Phosphate acyltransferases
HICPPONB_00024	6.75e-211	arbx	-	-	M	-	-	-	Glycosyl transferase family 8
HICPPONB_00025	4e-234	arbY	-	-	M	-	-	-	family 8
HICPPONB_00026	2.65e-213	arbZ	-	-	I	-	-	-	Phosphate acyltransferases
HICPPONB_00027	0.0	rafA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HICPPONB_00029	7.1e-274	sip	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HICPPONB_00030	8.97e-10	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HICPPONB_00032	1.4e-31	-	-	-	-	-	-	-	-
HICPPONB_00033	8.67e-17	-	-	-	-	-	-	-	-
HICPPONB_00034	5.8e-31	-	-	-	-	-	-	-	-
HICPPONB_00035	2.57e-46	-	-	-	-	-	-	-	-
HICPPONB_00036	1.96e-33	-	-	-	-	-	-	-	-
HICPPONB_00037	2.61e-197	-	-	-	L	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
HICPPONB_00038	0.0	-	-	-	S	-	-	-	Virulence-associated protein E
HICPPONB_00040	1.14e-105	terS	-	-	L	-	-	-	Phage terminase, small subunit
HICPPONB_00041	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
HICPPONB_00042	1.04e-29	-	-	-	-	-	-	-	-
HICPPONB_00043	1.09e-274	-	-	-	S	-	-	-	Phage portal protein
HICPPONB_00044	0.0	-	-	-	S	ko:K06904	-	ko00000	Phage capsid family
HICPPONB_00045	2.28e-63	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HICPPONB_00046	4.82e-18	-	-	-	S	-	-	-	Phage head-tail joining protein
HICPPONB_00047	2.3e-23	-	-	-	-	-	-	-	-
HICPPONB_00048	1.4e-35	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
HICPPONB_00050	9.31e-93	-	-	-	S	-	-	-	SdpI/YhfL protein family
HICPPONB_00051	3.55e-174	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
HICPPONB_00052	0.0	yclK	-	-	T	-	-	-	Histidine kinase
HICPPONB_00053	3.83e-96	-	-	-	S	-	-	-	acetyltransferase
HICPPONB_00054	5.2e-20	-	-	-	-	-	-	-	-
HICPPONB_00055	7.36e-94	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
HICPPONB_00056	1.53e-88	-	-	-	-	-	-	-	-
HICPPONB_00057	8.56e-74	-	-	-	-	-	-	-	-
HICPPONB_00058	0.0	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
HICPPONB_00060	7.89e-254	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
HICPPONB_00061	7.09e-180	-	3.1.1.5	-	E	ko:K10804	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	GDSL-like Lipase/Acylhydrolase
HICPPONB_00062	5.65e-46	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF898)
HICPPONB_00064	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HICPPONB_00065	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HICPPONB_00066	4.26e-271	camS	-	-	S	-	-	-	sex pheromone
HICPPONB_00067	3.61e-61	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HICPPONB_00068	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HICPPONB_00069	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HICPPONB_00070	4.97e-248	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
HICPPONB_00071	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HICPPONB_00072	1.31e-280	yttB	-	-	EGP	-	-	-	Major Facilitator
HICPPONB_00073	2.53e-190	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HICPPONB_00074	8.52e-211	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
HICPPONB_00075	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HICPPONB_00076	0.0	-	-	-	EGP	-	-	-	Major Facilitator
HICPPONB_00077	5.98e-105	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HICPPONB_00078	2.87e-213	yitS	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HICPPONB_00079	3.38e-166	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
HICPPONB_00080	1.24e-39	-	-	-	-	-	-	-	-
HICPPONB_00081	2.06e-179	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HICPPONB_00082	9.39e-80	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HICPPONB_00083	1.9e-79	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
HICPPONB_00084	6.33e-226	mocA	-	-	S	-	-	-	Oxidoreductase
HICPPONB_00085	4.41e-289	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
HICPPONB_00086	7.9e-74	chbA	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system
HICPPONB_00087	4.49e-93	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HICPPONB_00089	2.59e-06	-	-	-	-	-	-	-	-
HICPPONB_00090	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HICPPONB_00091	1.16e-305	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	Thermophilic metalloprotease (M29)
HICPPONB_00092	1.21e-143	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HICPPONB_00093	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
HICPPONB_00094	9.73e-230	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HICPPONB_00095	1.24e-103	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HICPPONB_00096	1.16e-204	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
HICPPONB_00097	5.25e-259	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HICPPONB_00099	1.02e-20	-	-	-	-	-	-	-	-
HICPPONB_00100	1.09e-253	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
HICPPONB_00101	4.58e-217	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HICPPONB_00105	8.83e-36	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HICPPONB_00106	2.17e-38	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HICPPONB_00108	8.24e-306	secA2	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HICPPONB_00109	4.22e-94	secY2	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	SecY translocase
HICPPONB_00110	5.88e-41	asp1	-	-	S	ko:K12268	-	ko00000,ko02044	Accessory Sec system protein Asp1
HICPPONB_00111	7.75e-45	asp2	-	-	S	ko:K12269	-	ko00000,ko02044	Accessory Sec system GspB-transporter
HICPPONB_00112	0.0	bglH	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HICPPONB_00113	1.23e-191	licT2	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HICPPONB_00114	0.0	-	-	-	S	-	-	-	Bacterial membrane protein YfhO
HICPPONB_00115	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HICPPONB_00116	4.76e-217	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
HICPPONB_00117	5.17e-134	-	-	-	-	-	-	-	-
HICPPONB_00118	8.49e-217	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
HICPPONB_00119	6.22e-43	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HICPPONB_00120	3.95e-108	yvbK	-	-	K	-	-	-	GNAT family
HICPPONB_00121	1.45e-149	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
HICPPONB_00122	5.35e-133	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HICPPONB_00123	6.23e-303	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
HICPPONB_00124	1.15e-261	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HICPPONB_00125	9.74e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HICPPONB_00126	7.06e-117	-	-	-	-	-	-	-	-
HICPPONB_00127	8.65e-252	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HICPPONB_00128	1.01e-200	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
HICPPONB_00129	4.12e-145	-	-	-	M	-	-	-	Acyltransferase family
HICPPONB_00130	1.47e-219	-	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
HICPPONB_00131	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HICPPONB_00132	6.87e-294	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
HICPPONB_00133	4.8e-77	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HICPPONB_00134	2.1e-126	tagF	2.7.8.12	-	M	ko:K09809,ko:K19046	-	ko00000,ko01000,ko02048	Glycosyl transferase, family 2
HICPPONB_00135	5.13e-243	-	-	-	M	-	-	-	Glycosyl transferases group 1
HICPPONB_00136	3.04e-305	-	-	-	S	-	-	-	polysaccharide biosynthetic process
HICPPONB_00137	1.46e-119	ywqC	-	-	M	ko:K16554	ko05111,map05111	ko00000,ko00001,ko02000	capsule polysaccharide biosynthetic process
HICPPONB_00138	8.98e-100	-	-	-	D	-	-	-	Capsular exopolysaccharide family
HICPPONB_00139	8.04e-220	-	-	-	S	-	-	-	EpsG family
HICPPONB_00140	0.0	-	-	-	M	-	-	-	Sulfatase
HICPPONB_00141	1.39e-200	nodB3	-	-	G	-	-	-	Polysaccharide deacetylase
HICPPONB_00142	4.57e-304	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HICPPONB_00143	2.01e-210	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HICPPONB_00144	0.0	-	-	-	E	-	-	-	Amino Acid
HICPPONB_00145	2.68e-174	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HICPPONB_00146	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HICPPONB_00147	9.49e-163	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
HICPPONB_00148	2e-240	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
HICPPONB_00149	2.2e-307	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HICPPONB_00150	3.71e-105	yjhE	-	-	S	-	-	-	Phage tail protein
HICPPONB_00151	1.97e-230	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HICPPONB_00152	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
HICPPONB_00153	7.47e-30	-	-	-	-	-	-	-	-
HICPPONB_00154	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HICPPONB_00155	5.02e-110	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
HICPPONB_00156	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HICPPONB_00157	1.13e-54	-	-	-	-	-	-	-	-
HICPPONB_00159	7.71e-227	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HICPPONB_00160	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HICPPONB_00161	1.88e-57	-	-	-	L	-	-	-	Reverse transcriptase (RNA-dependent DNA polymerase)
HICPPONB_00163	3.06e-39	-	-	-	L	-	-	-	L COG5421 Transposase
HICPPONB_00165	4.37e-68	-	2.7.11.1	-	KLT	ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
HICPPONB_00166	7.5e-128	yjdB	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HICPPONB_00167	7.74e-68	lciIC	-	-	K	-	-	-	Helix-turn-helix domain
HICPPONB_00169	2e-166	-	-	-	K	-	-	-	DeoR C terminal sensor domain
HICPPONB_00171	1.37e-172	zmp3	-	-	O	-	-	-	Zinc-dependent metalloprotease
HICPPONB_00172	0.0	-	-	-	M	-	-	-	LysM domain
HICPPONB_00174	1.28e-31	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
HICPPONB_00175	1.32e-74	-	2.7.1.39	-	S	ko:K02204	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Phosphotransferase enzyme family
HICPPONB_00176	3.24e-89	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HICPPONB_00178	0.0	-	-	-	V	ko:K06147,ko:K06148,ko:K11085,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter transmembrane region
HICPPONB_00179	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
HICPPONB_00180	3.73e-49	-	-	-	-	-	-	-	-
HICPPONB_00181	2.12e-70	-	-	-	K	-	-	-	Transcriptional
HICPPONB_00182	1.98e-163	-	-	-	S	-	-	-	DJ-1/PfpI family
HICPPONB_00183	0.0	-	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HICPPONB_00184	1.4e-213	-	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HICPPONB_00185	1.6e-224	-	-	-	EP	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HICPPONB_00187	3.97e-254	-	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
HICPPONB_00188	2.72e-203	-	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
HICPPONB_00189	6.09e-130	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HICPPONB_00190	1.32e-15	-	-	-	-	-	-	-	-
HICPPONB_00191	2.19e-159	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HICPPONB_00192	2.73e-80	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
HICPPONB_00193	5.12e-207	-	-	-	S	-	-	-	Alpha beta hydrolase
HICPPONB_00194	6.11e-233	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HICPPONB_00195	1.65e-160	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HICPPONB_00196	0.0	-	-	-	EGP	-	-	-	Major Facilitator
HICPPONB_00197	9.83e-148	-	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
HICPPONB_00198	0.0	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
HICPPONB_00199	3.34e-215	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HICPPONB_00200	1.43e-173	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
HICPPONB_00201	2e-112	ORF00048	-	-	-	-	-	-	-
HICPPONB_00202	1.13e-75	padR	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
HICPPONB_00203	3.85e-137	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HICPPONB_00204	2.1e-114	-	-	-	K	-	-	-	GNAT family
HICPPONB_00205	2.68e-135	kptA	-	-	J	ko:K07559	-	ko00000,ko01000,ko03016	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
HICPPONB_00206	3.61e-55	-	-	-	-	-	-	-	-
HICPPONB_00207	1.17e-306	citM	-	-	C	ko:K03300	-	ko00000	Citrate transporter
HICPPONB_00208	4.33e-69	-	-	-	-	-	-	-	-
HICPPONB_00209	2.06e-60	oadG	-	-	I	-	-	-	Biotin-requiring enzyme
HICPPONB_00210	1.13e-250	oadB	4.1.1.3	-	C	ko:K01572	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Na+-transporting oxaloacetate decarboxylase beta subunit
HICPPONB_00211	3.26e-07	-	-	-	-	-	-	-	-
HICPPONB_00212	1.22e-227	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HICPPONB_00213	3.41e-65	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
HICPPONB_00214	7.46e-201	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
HICPPONB_00215	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
HICPPONB_00216	9.61e-119	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HICPPONB_00217	0.0	oadA	4.1.1.3	-	C	ko:K01571	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Conserved carboxylase domain
HICPPONB_00218	4.14e-163	citR	-	-	K	-	-	-	FCD
HICPPONB_00219	5.7e-199	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HICPPONB_00220	7.43e-97	-	-	-	-	-	-	-	-
HICPPONB_00221	2.59e-40	-	-	-	-	-	-	-	-
HICPPONB_00222	1.25e-201	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HICPPONB_00223	7.86e-202	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HICPPONB_00224	8.49e-150	sodA	1.15.1.1	-	C	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HICPPONB_00225	1.43e-25	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HICPPONB_00226	8.02e-114	-	-	-	-	-	-	-	-
HICPPONB_00227	1.36e-245	-	-	-	S	-	-	-	Protein of unknown function C-terminal (DUF3324)
HICPPONB_00228	8.44e-128	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HICPPONB_00229	4.81e-127	-	-	-	-	-	-	-	-
HICPPONB_00230	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HICPPONB_00231	2.4e-169	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
HICPPONB_00233	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
HICPPONB_00234	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
HICPPONB_00235	6.05e-10	-	-	-	K	-	-	-	Mga helix-turn-helix domain
HICPPONB_00236	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
HICPPONB_00237	1.1e-293	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HICPPONB_00238	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HICPPONB_00239	8.69e-239	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HICPPONB_00240	1.28e-160	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	ABC transporter
HICPPONB_00241	1.34e-200	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HICPPONB_00242	1.1e-258	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
HICPPONB_00243	1.83e-168	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HICPPONB_00244	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HICPPONB_00245	1.76e-196	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HICPPONB_00246	4.48e-205	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HICPPONB_00247	1.06e-201	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
HICPPONB_00248	1.57e-192	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HICPPONB_00249	1.01e-179	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HICPPONB_00250	3.82e-156	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HICPPONB_00251	0.0	yvlB	-	-	S	-	-	-	Putative adhesin
HICPPONB_00252	2.13e-49	-	-	-	-	-	-	-	-
HICPPONB_00253	3.07e-50	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
HICPPONB_00254	8.27e-223	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HICPPONB_00255	7.94e-202	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HICPPONB_00256	6.29e-250	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HICPPONB_00257	1.43e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HICPPONB_00258	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HICPPONB_00259	1.06e-146	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
HICPPONB_00260	4.73e-215	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HICPPONB_00261	5.98e-118	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HICPPONB_00262	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HICPPONB_00263	1.99e-153	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
HICPPONB_00264	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HICPPONB_00265	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HICPPONB_00266	2.56e-111	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HICPPONB_00267	8.53e-213	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HICPPONB_00268	2.99e-248	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HICPPONB_00269	9.63e-220	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HICPPONB_00270	7.84e-106	ohrR	-	-	K	ko:K18906	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
HICPPONB_00271	5.97e-132	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HICPPONB_00274	5.52e-241	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
HICPPONB_00275	2.1e-247	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HICPPONB_00276	2.16e-282	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HICPPONB_00277	2.81e-180	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HICPPONB_00278	2.05e-313	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HICPPONB_00279	5.21e-293	mdt(A)	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
HICPPONB_00280	3.81e-63	-	-	-	-	-	-	-	-
HICPPONB_00281	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HICPPONB_00282	5.04e-43	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HICPPONB_00283	4.01e-181	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
HICPPONB_00284	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HICPPONB_00285	7.43e-107	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HICPPONB_00286	2.69e-227	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HICPPONB_00287	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
HICPPONB_00288	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HICPPONB_00289	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HICPPONB_00290	3.49e-155	-	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HICPPONB_00291	1.3e-267	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HICPPONB_00292	0.0	dexB	3.2.1.70	-	G	ko:K01215	-	ko00000,ko01000	Alpha amylase, catalytic domain protein
HICPPONB_00293	1.04e-287	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HICPPONB_00294	3.13e-308	malF	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HICPPONB_00295	6.34e-194	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HICPPONB_00297	1.43e-35	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
HICPPONB_00298	1.78e-306	YSH1	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Metallo-beta-lactamase superfamily
HICPPONB_00299	8.67e-312	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HICPPONB_00300	1.1e-188	malF	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HICPPONB_00301	7.01e-213	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems, permease components
HICPPONB_00302	3.08e-248	malK	-	-	P	ko:K10112,ko:K17240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
HICPPONB_00303	3.63e-136	-	-	-	K	ko:K06977	-	ko00000	Acetyltransferase (GNAT) domain
HICPPONB_00304	7.57e-119	-	-	-	-	-	-	-	-
HICPPONB_00305	4e-203	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HICPPONB_00306	1.45e-166	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HICPPONB_00307	3.02e-228	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
HICPPONB_00308	3.18e-106	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
HICPPONB_00309	4.05e-18	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HICPPONB_00310	1.21e-209	ysdB	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HICPPONB_00311	1.8e-275	ysdA	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HICPPONB_00312	8.04e-129	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HICPPONB_00313	6.69e-193	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HICPPONB_00314	1.59e-211	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HICPPONB_00315	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HICPPONB_00316	1.97e-124	-	-	-	K	-	-	-	Cupin domain
HICPPONB_00317	9.1e-263	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HICPPONB_00318	1.44e-189	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HICPPONB_00319	2.88e-187	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HICPPONB_00320	3.46e-266	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HICPPONB_00322	1.2e-261	pbpX	-	-	V	-	-	-	Beta-lactamase
HICPPONB_00323	4.01e-240	ydbI	-	-	K	-	-	-	AI-2E family transporter
HICPPONB_00324	4.31e-166	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HICPPONB_00325	1.41e-85	gtcA2	-	-	S	-	-	-	Teichoic acid glycosylation protein
HICPPONB_00326	7.62e-219	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HICPPONB_00327	0.0	-	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HICPPONB_00328	3.51e-216	gbuC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
HICPPONB_00329	4.78e-188	gbuB	-	-	E	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
HICPPONB_00330	9.19e-285	gbuA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
HICPPONB_00331	1.39e-176	sfsA	-	-	S	ko:K06206	-	ko00000	Belongs to the SfsA family
HICPPONB_00332	2.6e-96	usp1	-	-	T	-	-	-	Universal stress protein family
HICPPONB_00333	0.0	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
HICPPONB_00334	2.89e-191	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HICPPONB_00335	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
HICPPONB_00336	2.77e-291	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HICPPONB_00337	0.0	-	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HICPPONB_00338	9.21e-270	floL	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	SPFH domain / Band 7 family
HICPPONB_00339	1.32e-51	-	-	-	-	-	-	-	-
HICPPONB_00340	2.9e-220	pfoSR	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
HICPPONB_00341	2.05e-225	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HICPPONB_00342	3.99e-278	aspC	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HICPPONB_00344	7.26e-58	-	-	-	-	-	-	-	-
HICPPONB_00345	1.5e-162	WQ51_05710	-	-	S	-	-	-	Mitochondrial biogenesis AIM24
HICPPONB_00346	3.28e-93	-	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
HICPPONB_00347	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HICPPONB_00349	2.21e-258	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HICPPONB_00350	4.15e-204	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HICPPONB_00351	3.26e-226	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HICPPONB_00352	2.73e-283	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HICPPONB_00353	9.96e-212	ysdB	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
HICPPONB_00354	2.14e-279	ysdA	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HICPPONB_00355	6.81e-86	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HICPPONB_00356	9.19e-209	CcmA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HICPPONB_00357	2.04e-141	-	-	-	I	-	-	-	ABC-2 family transporter protein
HICPPONB_00358	5.9e-187	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	reductase
HICPPONB_00359	1.24e-258	ald1	1.4.1.1	-	C	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
HICPPONB_00360	1.45e-236	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HICPPONB_00361	0.0	-	-	-	S	-	-	-	OPT oligopeptide transporter protein
HICPPONB_00362	3.4e-82	-	-	-	S	-	-	-	Coenzyme PQQ synthesis protein D (PqqD)
HICPPONB_00363	0.0	pepD3	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HICPPONB_00364	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HICPPONB_00365	8.81e-317	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
HICPPONB_00366	9.6e-125	-	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Bacterial regulatory proteins, tetR family
HICPPONB_00367	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HICPPONB_00368	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HICPPONB_00369	4.16e-199	bglG4	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HICPPONB_00370	0.0	msbA9	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
HICPPONB_00371	0.0	cydD1	-	-	CO	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
HICPPONB_00372	2.59e-97	-	-	-	S	-	-	-	NusG domain II
HICPPONB_00373	4.73e-209	-	-	-	M	-	-	-	Peptidoglycan-binding domain 1 protein
HICPPONB_00374	1.88e-244	-	-	-	E	-	-	-	glutamate:sodium symporter activity
HICPPONB_00375	2.7e-296	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
HICPPONB_00376	1.06e-262	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
HICPPONB_00377	1.31e-77	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HICPPONB_00378	2.5e-236	-	-	-	S	-	-	-	DUF218 domain
HICPPONB_00379	1.41e-103	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HICPPONB_00380	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
HICPPONB_00381	2.32e-199	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
HICPPONB_00382	3.48e-103	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
HICPPONB_00383	1.15e-111	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HICPPONB_00384	3.42e-202	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HICPPONB_00385	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HICPPONB_00386	9.48e-300	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HICPPONB_00387	2.28e-57	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HICPPONB_00388	2.29e-87	-	-	-	-	-	-	-	-
HICPPONB_00389	2.61e-163	-	-	-	-	-	-	-	-
HICPPONB_00390	4.35e-159	-	-	-	S	-	-	-	Tetratricopeptide repeat
HICPPONB_00391	3.44e-08	-	-	-	-	-	-	-	-
HICPPONB_00392	4.87e-187	-	-	-	-	-	-	-	-
HICPPONB_00393	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HICPPONB_00395	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HICPPONB_00396	2.63e-82	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HICPPONB_00397	1.28e-274	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HICPPONB_00398	4.66e-44	-	-	-	-	-	-	-	-
HICPPONB_00399	5.68e-83	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HICPPONB_00400	1.63e-111	queT	-	-	S	-	-	-	QueT transporter
HICPPONB_00401	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	GXGXG motif
HICPPONB_00402	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HICPPONB_00403	1.19e-168	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HICPPONB_00404	1.34e-154	-	-	-	S	-	-	-	(CBS) domain
HICPPONB_00405	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HICPPONB_00406	5.04e-232	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HICPPONB_00407	4.28e-131	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HICPPONB_00408	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HICPPONB_00409	0.0	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HICPPONB_00410	1.99e-53	yabO	-	-	J	-	-	-	S4 domain protein
HICPPONB_00411	7.17e-87	divIC	-	-	D	ko:K05589,ko:K13052	-	ko00000,ko03036	cell cycle
HICPPONB_00412	1.17e-105	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
HICPPONB_00413	4.44e-309	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HICPPONB_00414	1.14e-124	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HICPPONB_00415	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HICPPONB_00416	3.58e-207	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HICPPONB_00417	8.47e-208	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HICPPONB_00418	8.82e-241	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HICPPONB_00419	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HICPPONB_00420	9.32e-112	ykuL	-	-	S	-	-	-	CBS domain
HICPPONB_00421	1.9e-175	gla	-	-	U	ko:K02440	-	ko00000,ko02000	Major intrinsic protein
HICPPONB_00422	1.64e-125	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HICPPONB_00423	0.0	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HICPPONB_00424	6.77e-111	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HICPPONB_00425	2.38e-311	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HICPPONB_00426	6.97e-49	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HICPPONB_00427	9.86e-304	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
HICPPONB_00428	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HICPPONB_00429	1.04e-27	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
HICPPONB_00430	3.64e-70	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HICPPONB_00431	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HICPPONB_00432	1.89e-119	cvpA	-	-	S	-	-	-	Colicin V production protein
HICPPONB_00433	1.65e-47	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HICPPONB_00434	1.3e-69	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HICPPONB_00435	2.67e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HICPPONB_00436	4.89e-58	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HICPPONB_00438	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HICPPONB_00439	5.18e-222	-	-	-	-	-	-	-	-
HICPPONB_00440	0.0	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HICPPONB_00441	3.03e-229	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
HICPPONB_00442	1.13e-307	ytoI	-	-	K	-	-	-	DRTGG domain
HICPPONB_00443	1.46e-263	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HICPPONB_00444	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HICPPONB_00445	2.06e-150	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Helix-turn-helix diphteria tox regulatory element
HICPPONB_00446	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HICPPONB_00447	1.76e-85	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HICPPONB_00448	1.41e-288	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HICPPONB_00449	7.52e-263	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HICPPONB_00450	4.54e-241	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HICPPONB_00451	2.95e-133	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HICPPONB_00452	1.3e-136	yjbF	-	-	S	-	-	-	SNARE associated Golgi protein
HICPPONB_00453	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
HICPPONB_00454	1.93e-139	-	-	-	K	ko:K22106	-	ko00000,ko03000	Tetracycline repressor, C-terminal all-alpha domain
HICPPONB_00456	3.93e-142	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HICPPONB_00457	3.55e-222	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HICPPONB_00458	2.28e-136	opuCB	-	-	E	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HICPPONB_00459	8.51e-286	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HICPPONB_00462	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
HICPPONB_00463	3.61e-46	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
HICPPONB_00464	1.11e-126	dpsB	-	-	P	-	-	-	Belongs to the Dps family
HICPPONB_00465	1.23e-149	flp	-	-	K	ko:K21562	-	ko00000,ko03000	helix_turn_helix, cAMP Regulatory protein
HICPPONB_00466	2.2e-179	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HICPPONB_00467	1.21e-267	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HICPPONB_00468	2.12e-130	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
HICPPONB_00469	8.94e-177	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
HICPPONB_00470	1.19e-233	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HICPPONB_00471	6.19e-264	-	-	-	-	-	-	-	-
HICPPONB_00472	0.0	-	-	-	EGP	-	-	-	Major Facilitator
HICPPONB_00473	1.04e-139	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HICPPONB_00475	6.25e-158	-	-	-	-	-	-	-	-
HICPPONB_00476	1.32e-258	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-type transport system involved in multi-copper enzyme maturation permease component
HICPPONB_00477	1.48e-197	-	-	-	-	-	-	-	-
HICPPONB_00478	3.25e-154	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HICPPONB_00479	3.93e-78	-	-	-	S	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
HICPPONB_00481	4.98e-39	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
HICPPONB_00483	1.17e-82	yugI	-	-	J	ko:K07570	-	ko00000	general stress protein
HICPPONB_00484	2.99e-140	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HICPPONB_00485	1.35e-237	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HICPPONB_00486	2.26e-115	pgpA	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Phosphatidylglycerophosphatase A
HICPPONB_00487	8.69e-149	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
HICPPONB_00488	6.43e-146	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
HICPPONB_00489	1.34e-186	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HICPPONB_00490	1.02e-150	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
HICPPONB_00491	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HICPPONB_00492	3.02e-147	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HICPPONB_00493	2.69e-150	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
HICPPONB_00494	1.46e-241	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
HICPPONB_00495	9.98e-73	-	-	-	-	-	-	-	-
HICPPONB_00496	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
HICPPONB_00497	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
HICPPONB_00498	5.87e-177	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HICPPONB_00499	1.06e-163	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
HICPPONB_00500	0.0	pbp1B	2.4.1.129	GT51	M	ko:K03693,ko:K12551	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin binding protein transpeptidase domain
HICPPONB_00501	3.03e-232	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HICPPONB_00502	2.2e-274	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HICPPONB_00503	7.49e-117	yrxA	-	-	S	ko:K07105	-	ko00000	3H domain
HICPPONB_00504	4.84e-114	ytxH	-	-	S	-	-	-	YtxH-like protein
HICPPONB_00505	2.12e-46	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HICPPONB_00506	1.38e-197	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
HICPPONB_00507	2.4e-201	-	-	-	S	ko:K08974	-	ko00000	Domain of unknown function (DUF368)
HICPPONB_00508	8.92e-105	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HICPPONB_00509	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HICPPONB_00510	1.52e-57	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
HICPPONB_00511	1.56e-277	araT	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HICPPONB_00513	1.58e-220	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HICPPONB_00514	1.13e-252	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HICPPONB_00515	8.97e-294	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HICPPONB_00516	0.0	ybeC	-	-	E	-	-	-	amino acid
HICPPONB_00517	8.3e-123	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	DNA-templated transcription, initiation
HICPPONB_00543	9.73e-109	-	-	-	-	-	-	-	-
HICPPONB_00544	4.04e-79	-	-	-	S	-	-	-	MucBP domain
HICPPONB_00545	4.34e-151	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HICPPONB_00548	8.24e-168	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HICPPONB_00549	1.03e-43	-	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA
HICPPONB_00550	4.96e-41	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA
HICPPONB_00551	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HICPPONB_00552	6.28e-25	-	-	-	S	-	-	-	Virus attachment protein p12 family
HICPPONB_00553	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
HICPPONB_00554	8.15e-77	-	-	-	-	-	-	-	-
HICPPONB_00555	1.53e-291	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
HICPPONB_00556	0.0	-	-	-	G	-	-	-	MFS/sugar transport protein
HICPPONB_00557	6.13e-100	-	-	-	S	-	-	-	function, without similarity to other proteins
HICPPONB_00558	1.71e-87	-	-	-	-	-	-	-	-
HICPPONB_00559	7.65e-136	-	-	-	-	-	-	-	-
HICPPONB_00560	6.04e-137	-	-	-	-	-	-	-	-
HICPPONB_00561	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HICPPONB_00562	4.55e-143	vanZ	-	-	V	-	-	-	VanZ like family
HICPPONB_00563	1.33e-195	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HICPPONB_00564	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HICPPONB_00565	1.09e-99	-	-	-	S	-	-	-	Domain of unknown function DUF1829
HICPPONB_00566	1.72e-39	-	-	-	-	-	-	-	-
HICPPONB_00569	2.59e-55	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HICPPONB_00571	3.99e-196	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HICPPONB_00572	1.03e-73	-	-	-	S	-	-	-	Pfam Transposase IS66
HICPPONB_00573	2.76e-294	-	-	GT2,GT4	M	ko:K20444	-	ko00000,ko01000,ko01005,ko02000	Glycosyl transferases group 1
HICPPONB_00574	3.64e-219	ysjB	-	-	S	ko:K03810	-	ko00000	Oxidoreductase family, NAD-binding Rossmann fold
HICPPONB_00575	2.32e-109	guaD	-	-	FJ	-	-	-	MafB19-like deaminase
HICPPONB_00578	6.05e-103	tspO	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	TspO/MBR family
HICPPONB_00579	1.53e-19	-	-	-	-	-	-	-	-
HICPPONB_00580	4.42e-271	yttB	-	-	EGP	-	-	-	Major Facilitator
HICPPONB_00581	4.36e-136	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HICPPONB_00582	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HICPPONB_00588	3.53e-73	-	-	-	S	-	-	-	virulence-associated E family protein
HICPPONB_00589	1.1e-93	-	-	-	L	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
HICPPONB_00597	6.39e-152	sip	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HICPPONB_00600	3.37e-162	pgm7	-	-	G	-	-	-	Phosphoglycerate mutase family
HICPPONB_00601	6.41e-155	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HICPPONB_00602	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HICPPONB_00603	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HICPPONB_00604	1.75e-179	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HICPPONB_00605	8.82e-207	catE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
HICPPONB_00606	3.56e-249	ampC	-	-	V	-	-	-	Beta-lactamase
HICPPONB_00607	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
HICPPONB_00608	4.41e-143	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HICPPONB_00609	8.62e-252	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HICPPONB_00610	2.32e-196	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HICPPONB_00611	1.2e-238	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HICPPONB_00612	6.38e-298	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HICPPONB_00613	3.05e-145	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HICPPONB_00614	2.89e-161	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HICPPONB_00615	2.57e-37	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HICPPONB_00616	1.13e-83	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HICPPONB_00617	3.93e-116	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HICPPONB_00618	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HICPPONB_00619	1.92e-211	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HICPPONB_00620	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HICPPONB_00621	1.88e-91	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HICPPONB_00622	8.38e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
HICPPONB_00623	4.12e-228	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
HICPPONB_00624	1.37e-26	-	-	-	S	-	-	-	DNA-directed RNA polymerase subunit beta
HICPPONB_00625	1.14e-72	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
HICPPONB_00626	8.37e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
HICPPONB_00627	1.41e-285	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HICPPONB_00628	1.71e-64	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
HICPPONB_00629	7.66e-268	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HICPPONB_00630	1.54e-185	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HICPPONB_00632	8.04e-192	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HICPPONB_00633	2.09e-243	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HICPPONB_00634	1.31e-149	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HICPPONB_00635	2.4e-183	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
HICPPONB_00636	4.72e-244	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
HICPPONB_00637	4.87e-280	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HICPPONB_00638	4.94e-103	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
HICPPONB_00639	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
HICPPONB_00640	4.73e-31	-	-	-	-	-	-	-	-
HICPPONB_00641	9.85e-88	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HICPPONB_00642	8.7e-231	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
HICPPONB_00643	2.13e-149	yhfA	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
HICPPONB_00644	2.7e-200	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HICPPONB_00645	2.86e-108	uspA	-	-	T	-	-	-	universal stress protein
HICPPONB_00646	3.9e-51	-	-	-	-	-	-	-	-
HICPPONB_00648	1.59e-304	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HICPPONB_00649	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HICPPONB_00650	2.76e-99	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HICPPONB_00651	7e-142	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
HICPPONB_00652	1.02e-158	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
HICPPONB_00653	3.79e-192	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HICPPONB_00654	1.89e-157	-	-	-	G	-	-	-	alpha-ribazole phosphatase activity
HICPPONB_00655	8.09e-197	mrsA1	1.8.4.11	-	O	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HICPPONB_00656	7.06e-220	-	-	-	IQ	-	-	-	NAD dependent epimerase/dehydratase family
HICPPONB_00657	2.93e-178	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HICPPONB_00658	2.05e-173	-	-	-	F	-	-	-	deoxynucleoside kinase
HICPPONB_00659	1.3e-56	-	-	-	-	-	-	-	-
HICPPONB_00660	2.86e-20	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HICPPONB_00661	3.29e-193	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphatase and related hydrolases of the PHP family
HICPPONB_00662	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HICPPONB_00663	5.88e-201	-	-	-	T	-	-	-	GHKL domain
HICPPONB_00664	2.69e-156	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
HICPPONB_00665	1.17e-217	bcrA	-	-	V	ko:K01990,ko:K19309	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HICPPONB_00666	1.83e-128	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HICPPONB_00667	1.4e-205	-	-	-	K	-	-	-	Transcriptional regulator
HICPPONB_00668	4.51e-101	yphH	-	-	S	-	-	-	Cupin domain
HICPPONB_00669	1.07e-72	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
HICPPONB_00670	6.41e-148	-	-	-	GM	-	-	-	NAD(P)H-binding
HICPPONB_00671	1.12e-53	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HICPPONB_00672	1.93e-157	gst	2.5.1.18	-	O	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	ko00000,ko00001,ko01000,ko02000	Glutathione S-transferase, C-terminal domain
HICPPONB_00673	2.22e-144	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HICPPONB_00674	3.33e-211	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HICPPONB_00675	1.76e-114	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HICPPONB_00676	9.8e-198	degV	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HICPPONB_00677	2.07e-135	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
HICPPONB_00678	2.43e-264	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HICPPONB_00679	6.76e-169	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HICPPONB_00680	3.28e-201	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HICPPONB_00681	2.19e-272	-	-	-	-	-	-	-	-
HICPPONB_00682	2.6e-39	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HICPPONB_00683	1.57e-62	-	-	-	S	-	-	-	Protein of unknown function (DUF2568)
HICPPONB_00684	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
HICPPONB_00685	3.12e-90	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HICPPONB_00686	2.88e-15	-	-	-	M	-	-	-	LysM domain
HICPPONB_00688	9.36e-35	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HICPPONB_00691	1.77e-22	-	-	-	-	-	-	-	-
HICPPONB_00692	2.69e-143	-	-	-	D	-	-	-	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HICPPONB_00694	1.47e-105	-	-	-	L	-	-	-	Replication protein
HICPPONB_00696	1.64e-120	-	-	-	L	-	-	-	Phage integrase family
HICPPONB_00697	5.31e-143	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HICPPONB_00698	7.1e-111	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
HICPPONB_00699	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HICPPONB_00700	8.67e-272	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HICPPONB_00701	2.45e-288	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HICPPONB_00702	7.15e-148	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HICPPONB_00703	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HICPPONB_00704	3.63e-307	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HICPPONB_00705	1.98e-148	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HICPPONB_00706	1.97e-152	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
HICPPONB_00707	4.82e-229	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
HICPPONB_00708	1.88e-191	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HICPPONB_00709	2.48e-112	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
HICPPONB_00710	2.69e-148	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HICPPONB_00711	8.63e-182	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
HICPPONB_00712	4.79e-142	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HICPPONB_00713	3.29e-146	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
HICPPONB_00714	2.32e-193	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HICPPONB_00715	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HICPPONB_00716	7.11e-60	-	-	-	-	-	-	-	-
HICPPONB_00717	1.61e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HICPPONB_00718	1.66e-219	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HICPPONB_00719	1.6e-68	ftsL	-	-	D	-	-	-	cell division protein FtsL
HICPPONB_00720	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HICPPONB_00721	1.33e-230	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HICPPONB_00722	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HICPPONB_00723	3.29e-258	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HICPPONB_00724	3.57e-201	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HICPPONB_00725	1.44e-311	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HICPPONB_00726	9.31e-291	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HICPPONB_00727	7.24e-102	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HICPPONB_00728	5.58e-60	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	integral membrane protein
HICPPONB_00729	7.18e-187	ylmH	-	-	S	-	-	-	S4 domain protein
HICPPONB_00730	4.21e-120	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA protein
HICPPONB_00731	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HICPPONB_00732	1.88e-47	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HICPPONB_00733	5.93e-207	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HICPPONB_00734	0.0	ydiC1	-	-	EGP	-	-	-	Major Facilitator
HICPPONB_00735	7.29e-270	yaaN	-	-	P	-	-	-	Toxic anion resistance protein (TelA)
HICPPONB_00736	9.37e-150	-	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
HICPPONB_00737	1.06e-123	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HICPPONB_00738	1.42e-39	-	-	-	-	-	-	-	-
HICPPONB_00739	4.6e-158	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HICPPONB_00740	2.81e-278	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HICPPONB_00741	1.21e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
HICPPONB_00742	0.0	uvrA2	-	-	L	-	-	-	ABC transporter
HICPPONB_00743	4.98e-305	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HICPPONB_00745	4.69e-159	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
HICPPONB_00746	1.62e-151	-	-	-	S	-	-	-	repeat protein
HICPPONB_00747	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HICPPONB_00748	4.74e-311	-	-	-	S	-	-	-	Sterol carrier protein domain
HICPPONB_00749	3.29e-232	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HICPPONB_00750	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HICPPONB_00751	2.02e-43	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HICPPONB_00752	1.11e-95	-	-	-	-	-	-	-	-
HICPPONB_00753	1.73e-63	-	-	-	-	-	-	-	-
HICPPONB_00754	4.82e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HICPPONB_00755	6.88e-110	-	-	-	S	-	-	-	E1-E2 ATPase
HICPPONB_00756	1.42e-267	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
HICPPONB_00757	1.15e-232	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
HICPPONB_00758	0.0	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HICPPONB_00759	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
HICPPONB_00760	6.14e-202	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	L-malate dehydrogenase activity
HICPPONB_00761	6.15e-62	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
HICPPONB_00762	3.56e-189	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
HICPPONB_00763	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HICPPONB_00764	4.76e-269	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HICPPONB_00765	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HICPPONB_00766	8.46e-84	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
HICPPONB_00767	5.74e-129	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
HICPPONB_00768	1.08e-113	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HICPPONB_00769	1.05e-232	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HICPPONB_00770	1.48e-147	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
HICPPONB_00771	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HICPPONB_00772	7.21e-222	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HICPPONB_00773	1.44e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HICPPONB_00774	5e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HICPPONB_00775	3.33e-63	-	-	-	-	-	-	-	-
HICPPONB_00776	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HICPPONB_00777	1.93e-213	-	-	-	S	-	-	-	Tetratricopeptide repeat
HICPPONB_00778	4.73e-286	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HICPPONB_00779	0.0	yknV	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
HICPPONB_00780	2.74e-287	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HICPPONB_00781	1.19e-296	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HICPPONB_00782	2.74e-138	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HICPPONB_00783	2.28e-63	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
HICPPONB_00784	3.33e-28	-	-	-	-	-	-	-	-
HICPPONB_00785	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HICPPONB_00786	1.89e-172	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HICPPONB_00787	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HICPPONB_00788	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
HICPPONB_00789	2.76e-218	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HICPPONB_00790	2.78e-170	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
HICPPONB_00791	3.37e-309	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HICPPONB_00792	0.0	oatA	-	-	I	-	-	-	Acyltransferase
HICPPONB_00793	2.71e-233	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HICPPONB_00794	1.83e-183	yqjQ	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
HICPPONB_00795	2.47e-65	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
HICPPONB_00796	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HICPPONB_00797	1.35e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HICPPONB_00798	6.3e-123	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HICPPONB_00799	0.0	ycjM	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	5'-nucleotidase, C-terminal domain
HICPPONB_00800	2.47e-184	-	-	-	-	-	-	-	-
HICPPONB_00801	9.49e-35	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HICPPONB_00802	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HICPPONB_00803	2.21e-227	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HICPPONB_00804	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HICPPONB_00805	4.31e-95	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
HICPPONB_00806	5.96e-207	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
HICPPONB_00807	9.95e-211	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
HICPPONB_00808	1.59e-88	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HICPPONB_00809	1.07e-159	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HICPPONB_00810	8.74e-139	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HICPPONB_00811	6.35e-175	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HICPPONB_00812	1.52e-123	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HICPPONB_00813	1.16e-60	fer	-	-	C	ko:K05337	-	ko00000	4Fe-4S single cluster domain of Ferredoxin I
HICPPONB_00814	4.14e-231	-	-	-	S	-	-	-	Helix-turn-helix domain
HICPPONB_00815	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HICPPONB_00816	6.85e-104	-	-	-	M	-	-	-	Lysin motif
HICPPONB_00817	2.04e-149	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HICPPONB_00818	1.72e-303	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HICPPONB_00819	7.41e-312	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HICPPONB_00820	1.2e-54	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HICPPONB_00821	1.52e-302	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
HICPPONB_00822	8.71e-200	ypjC	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HICPPONB_00823	2.16e-283	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HICPPONB_00824	2.95e-110	-	-	-	-	-	-	-	-
HICPPONB_00825	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HICPPONB_00826	9.91e-243	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HICPPONB_00827	3.64e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HICPPONB_00828	5.26e-148	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
HICPPONB_00829	4.9e-190	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
HICPPONB_00830	2.41e-196	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HICPPONB_00831	3.18e-147	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
HICPPONB_00832	1.28e-112	msrA	1.8.4.11	-	C	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HICPPONB_00833	1.03e-54	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HICPPONB_00834	1.72e-315	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HICPPONB_00835	7.24e-205	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HICPPONB_00836	2.31e-178	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HICPPONB_00837	7.71e-188	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
HICPPONB_00838	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HICPPONB_00839	2.84e-316	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HICPPONB_00840	1.66e-216	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
HICPPONB_00841	2.06e-119	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HICPPONB_00842	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HICPPONB_00843	5.38e-219	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HICPPONB_00844	6.92e-141	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HICPPONB_00846	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HICPPONB_00847	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HICPPONB_00848	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
HICPPONB_00849	2.56e-217	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HICPPONB_00850	5.25e-232	-	-	-	K	-	-	-	LysR substrate binding domain
HICPPONB_00851	9.27e-220	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
HICPPONB_00852	4.74e-266	xerS	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
HICPPONB_00853	7.18e-79	-	-	-	-	-	-	-	-
HICPPONB_00854	0.0	XK27_05700	-	-	V	ko:K02004,ko:K19084	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	FtsX-like permease family
HICPPONB_00855	2.68e-176	XK27_05695	-	-	V	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HICPPONB_00856	3.48e-219	kinG	-	-	T	-	-	-	Histidine kinase-like ATPases
HICPPONB_00857	1.18e-157	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
HICPPONB_00858	2.62e-241	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
HICPPONB_00859	8.72e-64	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HICPPONB_00860	1.73e-93	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HICPPONB_00861	2.92e-144	-	-	-	C	-	-	-	Nitroreductase family
HICPPONB_00862	8.08e-259	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HICPPONB_00863	8.66e-70	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
HICPPONB_00864	1.01e-77	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HICPPONB_00865	1.42e-169	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HICPPONB_00866	2.66e-158	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HICPPONB_00867	4.89e-146	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HICPPONB_00868	1.31e-134	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
HICPPONB_00869	1.69e-294	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HICPPONB_00870	2.06e-144	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HICPPONB_00871	3.15e-277	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HICPPONB_00872	1.7e-261	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HICPPONB_00873	4.76e-129	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
HICPPONB_00874	2.95e-205	-	-	-	S	-	-	-	EDD domain protein, DegV family
HICPPONB_00875	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
HICPPONB_00876	7.04e-66	-	-	-	S	-	-	-	MazG-like family
HICPPONB_00877	8.21e-250	pfoS/R	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
HICPPONB_00878	2.13e-227	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HICPPONB_00879	9.61e-289	bfmBB	2.3.1.12, 2.3.1.168	-	C	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoacid dehydrogenases acyltransferase (catalytic domain)
HICPPONB_00880	2.14e-234	bfmBAB	1.2.4.4	-	C	ko:K00167,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, pyrimidine binding domain
HICPPONB_00881	9.14e-239	bfmBAA	1.2.4.4	-	C	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
HICPPONB_00882	0.0	bfmBC	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
HICPPONB_00883	6.69e-263	buk	2.7.2.7	-	C	ko:K00929	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Acetokinase family
HICPPONB_00884	1.74e-190	ptb	2.3.1.19	-	C	ko:K00634	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Phosphate acetyl/butaryl transferase
HICPPONB_00885	1.02e-145	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HICPPONB_00886	2.67e-163	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HICPPONB_00887	7.42e-198	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HICPPONB_00888	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HICPPONB_00889	5.32e-267	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HICPPONB_00890	5.13e-305	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HICPPONB_00891	1.54e-228	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HICPPONB_00892	1.64e-299	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
HICPPONB_00893	1.05e-125	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HICPPONB_00894	5.18e-222	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HICPPONB_00895	2.41e-106	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HICPPONB_00896	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HICPPONB_00897	8.5e-61	-	-	-	S	-	-	-	Family of unknown function (DUF5322)
HICPPONB_00898	2.37e-91	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
HICPPONB_00899	2.09e-143	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
HICPPONB_00900	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HICPPONB_00901	1.57e-62	-	-	-	-	-	-	-	-
HICPPONB_00902	0.0	-	-	-	S	-	-	-	Mga helix-turn-helix domain
HICPPONB_00903	8.72e-52	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
HICPPONB_00904	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HICPPONB_00905	3.6e-241	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HICPPONB_00906	3.31e-207	lysR	-	-	K	-	-	-	Transcriptional regulator
HICPPONB_00907	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HICPPONB_00908	1e-248	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HICPPONB_00909	8.85e-47	-	-	-	-	-	-	-	-
HICPPONB_00910	7.06e-220	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HICPPONB_00911	9.39e-278	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HICPPONB_00912	7.09e-88	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HICPPONB_00913	1.87e-137	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HICPPONB_00914	5.12e-157	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HICPPONB_00915	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
HICPPONB_00916	5.94e-111	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
HICPPONB_00917	7.61e-148	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HICPPONB_00918	3.19e-146	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
HICPPONB_00919	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HICPPONB_00920	3.29e-279	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HICPPONB_00921	1.43e-111	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
HICPPONB_00922	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HICPPONB_00923	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HICPPONB_00924	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HICPPONB_00925	2.26e-216	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
HICPPONB_00926	3.82e-231	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
HICPPONB_00927	5.33e-243	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HICPPONB_00928	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
HICPPONB_00929	4.61e-224	-	-	-	-	-	-	-	-
HICPPONB_00930	3.71e-183	-	-	-	-	-	-	-	-
HICPPONB_00931	9.47e-79	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HICPPONB_00932	2.03e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
HICPPONB_00933	6.64e-190	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HICPPONB_00934	2.29e-160	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HICPPONB_00935	9.19e-249	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HICPPONB_00936	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HICPPONB_00937	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HICPPONB_00938	1.48e-219	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HICPPONB_00939	5.22e-56	-	-	-	-	-	-	-	-
HICPPONB_00940	3.64e-70	-	-	-	-	-	-	-	-
HICPPONB_00941	2.87e-181	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HICPPONB_00942	1.12e-215	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HICPPONB_00943	1.38e-84	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HICPPONB_00944	6.78e-82	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
HICPPONB_00945	1.03e-106	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HICPPONB_00946	8.02e-230	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
HICPPONB_00948	3.65e-88	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
HICPPONB_00949	3.98e-29	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HICPPONB_00950	8.44e-199	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HICPPONB_00951	6.81e-208	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HICPPONB_00952	3.1e-216	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HICPPONB_00953	8.83e-107	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HICPPONB_00954	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HICPPONB_00955	1.32e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HICPPONB_00956	4.56e-47	XK27_04345	3.6.1.1	-	C	ko:K01507	ko00190,map00190	ko00000,ko00001,ko01000	Inorganic pyrophosphatase
HICPPONB_00957	0.0	-	-	-	-	-	-	-	-
HICPPONB_00958	2.41e-201	-	-	-	V	-	-	-	ABC transporter
HICPPONB_00959	9.64e-109	-	-	-	FG	-	-	-	adenosine 5'-monophosphoramidase activity
HICPPONB_00960	8.06e-314	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
HICPPONB_00961	1.35e-150	-	-	-	J	-	-	-	HAD-hyrolase-like
HICPPONB_00962	1.59e-99	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HICPPONB_00963	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HICPPONB_00964	5.49e-58	-	-	-	-	-	-	-	-
HICPPONB_00965	2.57e-169	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HICPPONB_00966	7.07e-222	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
HICPPONB_00967	1e-112	XK27_03960	-	-	S	-	-	-	Protein of unknown function (DUF3013)
HICPPONB_00968	1.21e-141	-	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HICPPONB_00969	2.23e-50	-	-	-	-	-	-	-	-
HICPPONB_00971	1.69e-147	-	-	-	L	-	-	-	Initiator Replication protein
HICPPONB_00972	1.06e-102	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HICPPONB_00973	2.79e-70	-	-	-	L	-	-	-	Helix-turn-helix domain
HICPPONB_00974	1.45e-46	-	-	-	-	-	-	-	-
HICPPONB_00975	5.93e-12	-	-	-	-	-	-	-	-
HICPPONB_00977	1.54e-73	nudA	-	-	S	-	-	-	ASCH
HICPPONB_00978	2.2e-225	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HICPPONB_00979	2.7e-298	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HICPPONB_00980	5.97e-285	ysaA	-	-	V	-	-	-	RDD family
HICPPONB_00981	1.01e-193	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HICPPONB_00982	1.29e-154	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HICPPONB_00983	5.89e-158	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
HICPPONB_00984	1.64e-204	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
HICPPONB_00985	2.7e-231	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HICPPONB_00986	4.13e-51	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
HICPPONB_00987	1.75e-203	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HICPPONB_00988	6.78e-130	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HICPPONB_00989	9.1e-190	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
HICPPONB_00990	2.57e-104	manR	2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204	-	G	ko:K02538,ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02806,ko:K02821,ko:K03491,ko:K11201,ko:K20112	ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	phosphoenolpyruvate-dependent sugar phosphotransferase system
HICPPONB_00991	1.35e-239	lacD	4.1.2.40	-	G	ko:K01635	ko00052,ko01100,ko02024,map00052,map01100,map02024	ko00000,ko00001,ko01000	Belongs to the aldolase LacD family
HICPPONB_00992	4.27e-221	yqhA	-	-	G	-	-	-	Aldose 1-epimerase
HICPPONB_00993	1.95e-158	-	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HICPPONB_00994	4.01e-206	-	-	-	T	-	-	-	GHKL domain
HICPPONB_00995	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HICPPONB_00996	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HICPPONB_00997	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HICPPONB_00998	4.11e-223	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HICPPONB_00999	1.46e-196	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
HICPPONB_01000	6.34e-118	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HICPPONB_01001	3.11e-218	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HICPPONB_01002	9.14e-139	yiiE	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HICPPONB_01003	8.06e-165	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
HICPPONB_01004	6.41e-24	-	-	-	-	-	-	-	-
HICPPONB_01005	9.27e-219	-	-	-	-	-	-	-	-
HICPPONB_01007	1.31e-124	yxkA	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HICPPONB_01008	4.7e-50	-	-	-	-	-	-	-	-
HICPPONB_01009	1.32e-202	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
HICPPONB_01010	2.57e-223	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HICPPONB_01011	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HICPPONB_01012	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HICPPONB_01013	1.74e-224	ydhF	-	-	S	-	-	-	Aldo keto reductase
HICPPONB_01014	5.94e-198	-	-	-	Q	-	-	-	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
HICPPONB_01015	2.76e-120	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HICPPONB_01016	5.58e-306	dinF	-	-	V	-	-	-	MatE
HICPPONB_01017	7.19e-157	-	-	-	S	ko:K06872	-	ko00000	TPM domain
HICPPONB_01018	1.4e-133	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HICPPONB_01019	1.48e-246	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HICPPONB_01020	1.36e-254	-	-	-	V	-	-	-	efflux transmembrane transporter activity
HICPPONB_01021	8.33e-315	gshR	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HICPPONB_01022	6.07e-225	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HICPPONB_01023	0.0	choS	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HICPPONB_01025	0.0	-	-	-	L	-	-	-	DNA helicase
HICPPONB_01026	3.27e-192	rlrG	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
HICPPONB_01027	9.94e-219	ydiA	-	-	P	ko:K11041	ko05150,map05150	ko00000,ko00001,ko02042	Voltage-dependent anion channel
HICPPONB_01028	3.15e-145	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HICPPONB_01030	7.3e-149	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HICPPONB_01031	6.41e-92	-	-	-	K	-	-	-	MarR family
HICPPONB_01032	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC
HICPPONB_01033	2.55e-245	yghZ	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
HICPPONB_01034	5.86e-187	-	-	-	S	-	-	-	hydrolase
HICPPONB_01035	4.04e-79	-	-	-	-	-	-	-	-
HICPPONB_01036	1.99e-16	-	-	-	-	-	-	-	-
HICPPONB_01037	3.43e-138	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
HICPPONB_01038	1.56e-161	gpmB	-	-	G	ko:K15640	-	ko00000	Phosphoglycerate mutase family
HICPPONB_01039	7.22e-197	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HICPPONB_01040	3.81e-115	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HICPPONB_01041	4.39e-213	-	-	-	K	-	-	-	LysR substrate binding domain
HICPPONB_01042	4.96e-290	-	-	-	EK	-	-	-	Aminotransferase, class I
HICPPONB_01043	1.97e-235	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HICPPONB_01044	4.42e-154	ydfK	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HICPPONB_01045	5.24e-116	-	-	-	-	-	-	-	-
HICPPONB_01046	0.0	fruC	2.7.1.202	-	GT	ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HICPPONB_01047	4.43e-222	fruK-1	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
HICPPONB_01048	2.36e-167	rpl	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HICPPONB_01049	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HICPPONB_01050	2.03e-34	-	-	-	T	-	-	-	PFAM SpoVT AbrB
HICPPONB_01051	2.01e-116	-	-	-	-	-	-	-	-
HICPPONB_01052	6.94e-285	dgoD	4.2.1.6, 4.2.1.8	-	M	ko:K01684,ko:K08323	ko00040,ko00052,ko01100,ko01120,map00040,map00052,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Mandelate racemase muconate lactonizing enzyme
HICPPONB_01053	3.29e-313	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HICPPONB_01054	5.86e-61	sgcB	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HICPPONB_01055	1.76e-104	-	2.7.1.200	-	GT	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HICPPONB_01056	5.89e-138	-	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
HICPPONB_01057	0.0	-	-	-	G	-	-	-	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HICPPONB_01058	1.59e-58	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HICPPONB_01059	5.16e-66	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HICPPONB_01060	0.0	bgl	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HICPPONB_01061	8.06e-200	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HICPPONB_01062	4.64e-313	-	-	-	S	ko:K09704	-	ko00000	Metal-independent alpha-mannosidase (GH125)
HICPPONB_01063	0.0	mngB	3.2.1.170	GH38	G	ko:K15524	-	ko00000,ko01000	Glycosyl hydrolases family 38 N-terminal domain
HICPPONB_01064	1.54e-307	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HICPPONB_01065	1.1e-172	-	-	-	K	ko:K03492	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HICPPONB_01066	1.51e-175	-	4.1.2.17	-	G	ko:K01628	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Class II Aldolase and Adducin N-terminal domain
HICPPONB_01068	0.0	pts36C	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HICPPONB_01069	1.52e-68	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HICPPONB_01070	6.08e-107	pts36A	2.7.1.200	-	G	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HICPPONB_01071	1.89e-185	rdrB	-	-	K	ko:K02444,ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
HICPPONB_01072	1.59e-206	-	-	-	J	-	-	-	Methyltransferase domain
HICPPONB_01073	0.0	-	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HICPPONB_01076	0.0	-	-	-	M	-	-	-	Right handed beta helix region
HICPPONB_01077	2e-96	-	-	-	-	-	-	-	-
HICPPONB_01078	0.0	-	-	-	M	-	-	-	Heparinase II/III N-terminus
HICPPONB_01080	2.4e-107	-	-	-	G	ko:K02744	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HICPPONB_01081	8.63e-185	agaD	-	-	G	ko:K02747	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
HICPPONB_01082	4.62e-184	-	-	-	G	ko:K02746	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HICPPONB_01083	4.94e-114	-	-	-	G	ko:K02745	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HICPPONB_01084	1.17e-293	ugl	3.2.1.180	GH88	S	ko:K18581	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
HICPPONB_01085	1.58e-203	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HICPPONB_01086	1.1e-179	-	-	-	K	-	-	-	Bacterial transcriptional regulator
HICPPONB_01087	2.17e-208	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HICPPONB_01088	6.38e-193	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HICPPONB_01089	1.34e-152	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
HICPPONB_01090	2.37e-248	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
HICPPONB_01091	1.06e-152	alkD	-	-	L	-	-	-	DNA alkylation repair enzyme
HICPPONB_01092	7.16e-163	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HICPPONB_01093	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HICPPONB_01094	1.37e-218	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
HICPPONB_01095	2.13e-152	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	phosphatase
HICPPONB_01096	3.98e-150	-	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
HICPPONB_01097	1.8e-316	kinE	-	-	T	-	-	-	Histidine kinase
HICPPONB_01098	1.33e-160	llrE	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
HICPPONB_01099	0.0	-	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase C-terminal domain
HICPPONB_01100	0.0	-	2.7.1.199, 2.7.1.208	-	G	ko:K02790,ko:K02791	ko00010,ko00500,ko00520,ko02060,map00010,map00500,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HICPPONB_01101	0.0	hylB	4.2.2.1	PL8	N	ko:K01727	-	ko00000,ko01000	Polysaccharide lyase family 8, N terminal alpha-helical domain
HICPPONB_01102	0.0	-	-	-	-	-	-	-	-
HICPPONB_01104	3.41e-141	-	-	-	-	-	-	-	-
HICPPONB_01105	1.24e-109	-	-	-	-	-	-	-	-
HICPPONB_01106	3.12e-169	-	-	-	K	-	-	-	Mga helix-turn-helix domain
HICPPONB_01107	3.79e-153	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HICPPONB_01108	1.49e-108	ptbA	2.7.1.208	-	G	ko:K02755,ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HICPPONB_01109	3.95e-86	-	-	-	S	-	-	-	Uncharacterised protein family UPF0047
HICPPONB_01110	1.84e-96	-	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Triose-phosphate isomerase
HICPPONB_01111	1.75e-122	gatY	4.1.2.13, 4.1.2.40	-	G	ko:K01624,ko:K08302	ko00010,ko00030,ko00051,ko00052,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
HICPPONB_01112	1.57e-39	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system, galactitol-specific IIB component
HICPPONB_01113	7.38e-204	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HICPPONB_01114	1.33e-33	-	2.7.1.200	-	G	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HICPPONB_01116	3.51e-99	-	-	-	K	ko:K02538	-	ko00000,ko03000	PRD domain
HICPPONB_01117	1.14e-256	-	-	-	S	-	-	-	DUF218 domain
HICPPONB_01118	1.96e-155	pdxA	1.1.1.408, 1.1.1.409	-	H	ko:K22024	-	ko00000,ko01000	Belongs to the PdxA family
HICPPONB_01119	1.85e-109	-	2.7.1.219, 2.7.1.220	-	S	ko:K22129	-	ko00000,ko01000	Putative nucleotide-binding of sugar-metabolising enzyme
HICPPONB_01120	5.48e-132	kdgT	-	-	P	ko:K02526	-	ko00000,ko02000	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
HICPPONB_01121	1.13e-70	-	-	-	T	ko:K02667	ko02020,map02020	ko00000,ko00001,ko00002,ko02022,ko02035	phosphorelay signal transduction system
HICPPONB_01122	9.17e-87	kdsD	5.3.1.13	-	M	ko:K06041	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	SIS domain
HICPPONB_01123	8.2e-63	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HICPPONB_01124	8.29e-44	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HICPPONB_01125	1.77e-256	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HICPPONB_01126	1.79e-123	-	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
HICPPONB_01127	4.41e-104	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
HICPPONB_01128	4.07e-257	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HICPPONB_01129	5.63e-177	-	4.1.2.14	-	S	ko:K17463	ko00030,ko01100,ko01120,map00030,map01100,map01120	ko00000,ko00001,ko00002,ko01000	KDGP aldolase
HICPPONB_01130	8.75e-260	selA	2.9.1.1	-	H	ko:K01042	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko01000	L-seryl-tRNA selenium transferase
HICPPONB_01131	2.12e-275	dho	3.5.2.3	-	S	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Amidohydrolase family
HICPPONB_01132	3.79e-155	-	-	-	S	-	-	-	Domain of unknown function (DUF4310)
HICPPONB_01133	1.18e-176	-	-	-	S	-	-	-	Domain of unknown function (DUF4311)
HICPPONB_01134	1.1e-76	-	-	-	S	-	-	-	Domain of unknown function (DUF4312)
HICPPONB_01135	5.01e-80	-	-	-	S	-	-	-	Glycine-rich SFCGS
HICPPONB_01136	2.48e-72	-	-	-	S	-	-	-	PRD domain
HICPPONB_01137	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
HICPPONB_01138	8.74e-161	-	-	-	H	-	-	-	Pfam:Transaldolase
HICPPONB_01139	2.24e-84	-	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HICPPONB_01140	1.95e-250	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
HICPPONB_01141	5.81e-131	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
HICPPONB_01142	7.54e-115	srlM1	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
HICPPONB_01143	0.0	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
HICPPONB_01144	4.13e-185	srlD2	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
HICPPONB_01145	1.57e-177	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HICPPONB_01146	1.45e-193	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HICPPONB_01147	1.79e-211	sga	5.1.3.22	-	G	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Xylose isomerase-like TIM barrel
HICPPONB_01148	8.64e-178	-	-	-	K	-	-	-	DeoR C terminal sensor domain
HICPPONB_01149	5.26e-148	ulaD	4.1.1.85, 4.1.2.43	-	G	ko:K03078,ko:K08093	ko00030,ko00040,ko00053,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00040,map00053,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Orotidine 5'-phosphate decarboxylase / HUMPS family
HICPPONB_01150	3.36e-61	sgaB	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HICPPONB_01151	0.0	sgaT	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HICPPONB_01152	4.89e-105	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HICPPONB_01153	4.59e-275	ulaG	-	-	S	ko:K03476	ko00053,ko01100,ko01120,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Beta-lactamase superfamily domain
HICPPONB_01154	1.31e-196	-	-	-	G	-	-	-	Phosphotransferase System
HICPPONB_01155	1.03e-50	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HICPPONB_01156	1.92e-63	frvA	2.7.1.202	-	G	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HICPPONB_01158	1.55e-140	-	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
HICPPONB_01159	3.96e-102	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HICPPONB_01160	1.74e-198	-	-	-	GK	-	-	-	ROK family
HICPPONB_01161	2.13e-230	asnA2	3.5.1.1	-	E	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
HICPPONB_01162	0.0	-	-	-	E	-	-	-	Peptidase family M20/M25/M40
HICPPONB_01163	1.23e-168	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
HICPPONB_01164	0.0	-	4.1.1.12	-	E	ko:K09758	ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230	ko00000,ko00001,ko01000	Aminotransferase
HICPPONB_01165	2.37e-272	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
HICPPONB_01166	9.44e-262	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
HICPPONB_01167	3.1e-112	-	-	-	M	ko:K03828	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HICPPONB_01168	7.22e-131	laaE	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HICPPONB_01169	0.0	chaT1	-	-	U	ko:K03446	-	ko00000,ko00002,ko02000	the major facilitator superfamily
HICPPONB_01170	3.08e-113	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HICPPONB_01171	1.47e-120	yveA	-	-	Q	-	-	-	Isochorismatase family
HICPPONB_01172	5.18e-60	-	-	-	S	-	-	-	Zeta toxin
HICPPONB_01173	6.83e-164	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
HICPPONB_01174	1.13e-133	-	-	-	IQ	-	-	-	KR domain
HICPPONB_01175	6.41e-85	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HICPPONB_01176	4.09e-46	-	-	-	G	-	-	-	PTS system fructose IIA component
HICPPONB_01177	1.32e-310	-	-	-	G	-	-	-	PTS system sorbose-specific iic component
HICPPONB_01178	3.31e-193	-	-	-	E	-	-	-	Alcohol dehydrogenase GroES-like domain
HICPPONB_01179	3.93e-104	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HICPPONB_01180	2.25e-74	ps105	-	-	-	-	-	-	-
HICPPONB_01182	1.09e-124	-	-	-	K	-	-	-	Helix-turn-helix domain
HICPPONB_01183	9.3e-156	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HICPPONB_01184	2.24e-96	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HICPPONB_01185	0.0	ugpB	-	-	G	ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HICPPONB_01186	2.92e-192	ugpE	-	-	G	ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HICPPONB_01187	1.3e-210	-	-	-	P	ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type sugar transport systems, permease components
HICPPONB_01188	4.24e-270	ugpC	3.6.3.20	-	E	ko:K05816,ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the ABC transporter superfamily
HICPPONB_01189	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HICPPONB_01190	1.09e-138	pncA	-	-	Q	-	-	-	Isochorismatase family
HICPPONB_01191	5.44e-174	-	-	-	F	-	-	-	NUDIX domain
HICPPONB_01192	4.85e-186	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HICPPONB_01193	4.37e-243	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
HICPPONB_01194	3.49e-246	-	-	-	V	-	-	-	Beta-lactamase
HICPPONB_01195	1.43e-197	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HICPPONB_01196	3.72e-210	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HICPPONB_01197	1.67e-105	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HICPPONB_01198	1.56e-192	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
HICPPONB_01199	8.76e-177	XK27_08455	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HICPPONB_01200	3.04e-259	-	-	-	S	-	-	-	endonuclease exonuclease phosphatase family protein
HICPPONB_01201	1.32e-219	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
HICPPONB_01202	2.67e-131	-	-	-	Q	-	-	-	Methyltransferase
HICPPONB_01203	2.16e-68	sugE	-	-	U	ko:K11741	-	ko00000,ko02000	Multidrug resistance protein
HICPPONB_01204	1.38e-22	-	-	-	-	-	-	-	-
HICPPONB_01205	2.13e-171	-	-	-	S	-	-	-	-acetyltransferase
HICPPONB_01206	1.37e-120	yfbM	-	-	K	-	-	-	FR47-like protein
HICPPONB_01207	2.33e-120	-	-	-	E	-	-	-	HAD-hyrolase-like
HICPPONB_01208	8.39e-236	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HICPPONB_01209	1.33e-178	ptp1	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HICPPONB_01210	2.33e-120	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HICPPONB_01211	8.79e-105	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HICPPONB_01212	1.77e-90	-	-	-	K	ko:K03830	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HICPPONB_01213	1.19e-78	-	-	-	S	-	-	-	ASCH
HICPPONB_01214	1.01e-105	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HICPPONB_01215	6.32e-253	ysdE	-	-	P	-	-	-	Citrate transporter
HICPPONB_01216	8.69e-91	-	-	-	-	-	-	-	-
HICPPONB_01217	0.0	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
HICPPONB_01218	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HICPPONB_01220	4.2e-134	-	-	-	-	-	-	-	-
HICPPONB_01221	0.0	cadA	-	-	P	-	-	-	P-type ATPase
HICPPONB_01222	1.8e-99	hsp3	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HICPPONB_01223	2.35e-92	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HICPPONB_01224	1.7e-284	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
HICPPONB_01225	4.32e-196	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
HICPPONB_01226	1.05e-182	yycI	-	-	S	-	-	-	YycH protein
HICPPONB_01227	0.0	yycH	-	-	S	-	-	-	YycH protein
HICPPONB_01228	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HICPPONB_01229	3.03e-168	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HICPPONB_01230	3.54e-156	-	1.11.1.10	-	S	ko:K00433	-	ko00000,ko01000	Alpha/beta hydrolase family
HICPPONB_01231	0.0	arpJ	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HICPPONB_01232	1.63e-298	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HICPPONB_01233	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HICPPONB_01234	3.77e-270	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HICPPONB_01235	9.09e-97	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HICPPONB_01236	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HICPPONB_01237	1.97e-168	gntR	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
HICPPONB_01238	5.86e-68	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HICPPONB_01239	4.84e-71	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
HICPPONB_01240	6.11e-139	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HICPPONB_01241	1.84e-110	-	-	-	F	-	-	-	NUDIX domain
HICPPONB_01242	2.15e-116	-	-	-	S	-	-	-	AAA domain
HICPPONB_01243	3.32e-148	ycaC	-	-	Q	-	-	-	Isochorismatase family
HICPPONB_01244	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HICPPONB_01245	1.61e-273	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
HICPPONB_01246	2.11e-220	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
HICPPONB_01247	1.08e-84	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
HICPPONB_01248	2.45e-216	manN	-	-	G	ko:K02796,ko:K02815	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
HICPPONB_01249	1.57e-171	manM	-	-	G	ko:K02746,ko:K02795,ko:K02814	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
HICPPONB_01250	1.44e-230	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HICPPONB_01251	1.62e-277	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HICPPONB_01253	2.43e-241	-	-	-	K	ko:K20373	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
HICPPONB_01254	8.33e-193	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HICPPONB_01255	6.17e-204	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
HICPPONB_01257	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HICPPONB_01258	3.81e-172	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HICPPONB_01259	4.51e-41	-	-	-	-	-	-	-	-
HICPPONB_01260	1.21e-304	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HICPPONB_01261	1.89e-166	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
HICPPONB_01262	2.43e-52	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HICPPONB_01263	8.12e-69	-	-	-	-	-	-	-	-
HICPPONB_01264	8.68e-106	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
HICPPONB_01265	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Bacterial PH domain
HICPPONB_01266	3.16e-185	-	-	-	S	-	-	-	AAA ATPase domain
HICPPONB_01267	9.24e-214	-	-	-	G	-	-	-	Phosphotransferase enzyme family
HICPPONB_01268	2.2e-170	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HICPPONB_01269	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HICPPONB_01270	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HICPPONB_01271	2.69e-128	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HICPPONB_01272	7.75e-138	-	-	-	S	ko:K06384	-	ko00000	Stage II sporulation protein M
HICPPONB_01273	1.82e-182	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
HICPPONB_01274	7.49e-236	-	-	-	S	-	-	-	Protein of unknown function DUF58
HICPPONB_01275	0.0	yebA	-	-	E	-	-	-	Transglutaminase/protease-like homologues
HICPPONB_01276	1.42e-271	-	-	-	M	-	-	-	Glycosyl transferases group 1
HICPPONB_01277	2.22e-125	thgA3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HICPPONB_01278	2.13e-186	-	3.1.3.102, 3.1.3.104, 3.1.3.23	-	G	ko:K07757,ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
HICPPONB_01279	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
HICPPONB_01280	4.78e-146	-	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
HICPPONB_01281	3e-61	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
HICPPONB_01282	1.05e-271	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
HICPPONB_01283	5.39e-292	malP	-	-	C	ko:K11616	ko02020,map02020	ko00000,ko00001	2-hydroxycarboxylate transporter family
HICPPONB_01284	7e-07	dpiB	2.7.13.3	-	T	ko:K02476,ko:K11614	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Single cache domain 3
HICPPONB_01285	1.64e-302	-	-	-	L	ko:K07485	-	ko00000	Transposase
HICPPONB_01286	0.0	dpiB	2.7.13.3	-	T	ko:K02476,ko:K11614	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Single cache domain 3
HICPPONB_01287	6.6e-159	malR	-	-	KT	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	cheY-homologous receiver domain
HICPPONB_01288	1.56e-194	-	-	-	I	-	-	-	NAD binding domain of 6-phosphogluconate dehydrogenase
HICPPONB_01289	1.03e-121	M1-431	-	-	S	-	-	-	Protein of unknown function (DUF1706)
HICPPONB_01290	1.25e-83	-	-	-	-	-	-	-	-
HICPPONB_01291	8.73e-282	yagE	-	-	E	-	-	-	Amino acid permease
HICPPONB_01292	7.05e-219	-	-	-	O	-	-	-	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HICPPONB_01293	3.5e-88	-	-	-	V	-	-	-	Domain of unknown function (DUF3883)
HICPPONB_01298	1.87e-217	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HICPPONB_01299	2.32e-233	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
HICPPONB_01300	1.77e-237	lipA	-	-	I	-	-	-	Carboxylesterase family
HICPPONB_01301	6.85e-275	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
HICPPONB_01302	9.2e-101	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HICPPONB_01303	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
HICPPONB_01304	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HICPPONB_01305	2.05e-168	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HICPPONB_01306	3.86e-192	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HICPPONB_01307	5.93e-59	-	-	-	-	-	-	-	-
HICPPONB_01308	4.73e-19	-	-	-	-	-	-	-	-
HICPPONB_01309	1.02e-236	hlyD3	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HICPPONB_01310	7.13e-161	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HICPPONB_01311	2.53e-265	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HICPPONB_01312	0.0	-	-	-	M	-	-	-	Leucine rich repeats (6 copies)
HICPPONB_01313	1.49e-253	ypjH	-	-	C	ko:K08317	-	ko00000,ko01000	dehydrogenase
HICPPONB_01314	2.18e-288	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
HICPPONB_01315	1.48e-104	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HICPPONB_01316	1.25e-150	labL	-	-	S	-	-	-	Putative threonine/serine exporter
HICPPONB_01318	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HICPPONB_01319	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HICPPONB_01321	5.79e-170	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
HICPPONB_01322	3.06e-177	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HICPPONB_01323	2.45e-76	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HICPPONB_01324	3.26e-23	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
HICPPONB_01325	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HICPPONB_01326	1.02e-260	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HICPPONB_01327	4.07e-43	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
HICPPONB_01328	9.09e-260	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HICPPONB_01329	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HICPPONB_01330	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HICPPONB_01331	5.22e-163	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HICPPONB_01332	5.2e-98	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HICPPONB_01333	1.36e-65	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HICPPONB_01334	1.54e-114	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HICPPONB_01335	3.26e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HICPPONB_01336	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome bd terminal oxidase subunit I
HICPPONB_01337	3.29e-228	-	-	-	C	-	-	-	Cytochrome bd terminal oxidase subunit II
HICPPONB_01338	2.45e-48	-	-	-	-	-	-	-	-
HICPPONB_01339	9.81e-138	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HICPPONB_01342	5.26e-183	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HICPPONB_01345	1.44e-188	p40	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain
HICPPONB_01346	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HICPPONB_01347	1.76e-165	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HICPPONB_01348	1.68e-127	-	-	-	K	-	-	-	transcriptional regulator
HICPPONB_01349	1.77e-196	-	-	-	G	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HICPPONB_01350	2.85e-64	-	-	-	-	-	-	-	-
HICPPONB_01353	0.0	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
HICPPONB_01354	1.96e-158	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HICPPONB_01355	1.16e-131	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HICPPONB_01357	9.98e-56	-	-	-	-	-	-	-	-
HICPPONB_01358	8.19e-212	-	-	-	P	-	-	-	CorA-like Mg2+ transporter protein
HICPPONB_01359	3.84e-145	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HICPPONB_01361	2.37e-306	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HICPPONB_01362	2.96e-72	-	-	-	-	-	-	-	-
HICPPONB_01364	0.0	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HICPPONB_01365	1.69e-143	-	-	-	S	-	-	-	Membrane
HICPPONB_01366	4.1e-67	-	-	-	-	-	-	-	-
HICPPONB_01368	1.09e-126	-	-	-	-	-	-	-	-
HICPPONB_01369	1.31e-91	-	-	-	-	-	-	-	-
HICPPONB_01370	1.31e-80	-	-	-	-	-	-	-	-
HICPPONB_01371	2.17e-82	-	-	-	S	-	-	-	Nucleotidyl transferase AbiEii toxin, Type IV TA system
HICPPONB_01372	3.04e-98	-	-	-	-	-	-	-	-
HICPPONB_01373	9.28e-158	azlC	-	-	E	-	-	-	branched-chain amino acid
HICPPONB_01374	4.31e-65	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
HICPPONB_01376	5.57e-37	-	-	-	-	-	-	-	-
HICPPONB_01377	4.53e-185	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HICPPONB_01378	6.9e-150	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
HICPPONB_01379	1.5e-160	kdgR	-	-	K	-	-	-	FCD domain
HICPPONB_01381	2.84e-73	ps105	-	-	-	-	-	-	-
HICPPONB_01382	5.15e-205	-	-	-	K	-	-	-	Transcriptional activator, Rgg GadR MutR family
HICPPONB_01383	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
HICPPONB_01384	2.55e-305	-	-	-	EGP	-	-	-	Major Facilitator
HICPPONB_01386	3.02e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HICPPONB_01387	2.2e-176	-	-	-	S	-	-	-	Putative threonine/serine exporter
HICPPONB_01388	2.51e-98	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HICPPONB_01389	9.31e-273	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
HICPPONB_01390	1.04e-191	livH	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HICPPONB_01391	1.1e-182	livM	-	-	E	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HICPPONB_01392	3.52e-179	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
HICPPONB_01393	1.16e-159	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
HICPPONB_01394	7.59e-214	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HICPPONB_01395	6.2e-301	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HICPPONB_01396	4.1e-152	-	-	-	G	-	-	-	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HICPPONB_01397	1.01e-149	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HICPPONB_01398	1.08e-291	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HICPPONB_01399	3.82e-167	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
HICPPONB_01400	2.4e-202	p75	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
HICPPONB_01403	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
HICPPONB_01404	8.38e-177	-	-	-	-	-	-	-	-
HICPPONB_01405	1.96e-154	-	-	-	-	-	-	-	-
HICPPONB_01406	0.0	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
HICPPONB_01407	2.02e-306	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HICPPONB_01408	6.36e-110	-	-	-	-	-	-	-	-
HICPPONB_01409	0.0	strH	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Gram-positive signal peptide protein, YSIRK family
HICPPONB_01410	3.57e-246	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HICPPONB_01411	5.43e-167	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
HICPPONB_01412	9.86e-282	agaS	-	-	G	ko:K02082	-	ko00000,ko01000	SIS domain
HICPPONB_01413	9.18e-288	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HICPPONB_01414	0.0	bgaC	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Glycosyl hydrolases family 35
HICPPONB_01415	5.61e-108	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HICPPONB_01416	4.68e-206	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HICPPONB_01417	3.66e-187	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
HICPPONB_01418	1.57e-84	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HICPPONB_01419	1.03e-177	lacC	2.7.1.144	-	F	ko:K00917	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
HICPPONB_01420	3.51e-182	srlD	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	KR domain
HICPPONB_01421	2.82e-298	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HICPPONB_01422	2.36e-86	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HICPPONB_01423	1.58e-60	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HICPPONB_01424	4.05e-180	-	-	-	-	-	-	-	-
HICPPONB_01425	1.6e-288	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
HICPPONB_01426	1.51e-242	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HICPPONB_01427	8.99e-251	-	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HICPPONB_01428	0.0	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HICPPONB_01429	8.5e-78	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HICPPONB_01430	3.39e-67	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HICPPONB_01431	6.73e-239	-	-	-	E	-	-	-	M42 glutamyl aminopeptidase
HICPPONB_01432	0.0	-	-	-	GKT	ko:K03491	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HICPPONB_01433	2.02e-308	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HICPPONB_01434	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HICPPONB_01435	3.58e-155	-	-	-	S	ko:K03824	-	ko00000,ko01000	Acetyltransferase (GNAT) family
HICPPONB_01437	8.84e-121	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HICPPONB_01438	4.66e-312	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HICPPONB_01439	8.97e-141	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
HICPPONB_01440	1.39e-165	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HICPPONB_01441	5.11e-107	thiW	-	-	S	-	-	-	Thiamine-precursor transporter protein (ThiW)
HICPPONB_01442	1.18e-191	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HICPPONB_01443	6.07e-138	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HICPPONB_01444	6.07e-187	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HICPPONB_01445	0.0	-	-	-	E	-	-	-	Amino acid permease
HICPPONB_01446	3.34e-45	-	-	-	-	-	-	-	-
HICPPONB_01449	2.08e-240	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
HICPPONB_01450	2.2e-86	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HICPPONB_01451	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HICPPONB_01452	4.84e-198	rbsC	-	-	U	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HICPPONB_01453	1.41e-214	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein domain
HICPPONB_01454	1.34e-207	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HICPPONB_01455	0.0	pbpC	-	-	M	ko:K21467	-	ko00000,ko01011	NTF2-like N-terminal transpeptidase domain
HICPPONB_01456	2.71e-83	-	-	-	K	-	-	-	Transcriptional regulator
HICPPONB_01457	5.15e-260	choS	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HICPPONB_01458	3.66e-140	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HICPPONB_01459	6.04e-136	-	-	-	C	-	-	-	NADPH quinone reductase
HICPPONB_01460	6.22e-303	-	-	-	EGP	-	-	-	Major Facilitator
HICPPONB_01461	7.36e-94	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HICPPONB_01462	4.85e-128	-	-	-	-	-	-	-	-
HICPPONB_01463	8.28e-30	-	-	-	-	-	-	-	-
HICPPONB_01464	1.84e-81	-	-	-	-	-	-	-	-
HICPPONB_01465	2.17e-79	-	-	-	-	-	-	-	-
HICPPONB_01466	0.0	frdC	1.3.5.1, 1.3.5.4	-	C	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	ko00000,ko00001,ko00002,ko01000	HI0933-like protein
HICPPONB_01467	2.2e-248	-	-	-	GKT	-	-	-	transcriptional antiterminator
HICPPONB_01468	3.38e-66	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HICPPONB_01469	5.62e-292	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HICPPONB_01470	2.92e-89	-	-	-	-	-	-	-	-
HICPPONB_01471	6.47e-208	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
HICPPONB_01472	6.4e-149	-	-	-	S	-	-	-	Zeta toxin
HICPPONB_01473	3.2e-203	-	-	-	K	-	-	-	Sugar-specific transcriptional regulator TrmB
HICPPONB_01474	9.64e-191	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
HICPPONB_01475	5.02e-230	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	Ornithine cyclodeaminase/mu-crystallin family
HICPPONB_01476	1.11e-190	-	3.1.1.24	-	S	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Alpha/beta hydrolase family
HICPPONB_01478	1.98e-231	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HICPPONB_01479	1.42e-117	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HICPPONB_01481	2.37e-91	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
HICPPONB_01482	5.11e-93	yqeB	-	-	S	-	-	-	Pyrimidine dimer DNA glycosylase
HICPPONB_01483	4.82e-194	bla1	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase
HICPPONB_01484	1.4e-73	gntR	-	-	K	-	-	-	rpiR family
HICPPONB_01485	1.21e-47	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HICPPONB_01486	9.48e-231	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HICPPONB_01487	3.93e-34	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HICPPONB_01488	4.59e-161	-	-	-	S	-	-	-	N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity
HICPPONB_01489	3.71e-81	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HICPPONB_01490	1.33e-277	-	-	-	E	-	-	-	SAF
HICPPONB_01491	1.32e-71	-	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HICPPONB_01492	1.21e-130	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
HICPPONB_01493	3.55e-187	pts38BC	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
HICPPONB_01494	2.93e-09	-	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
HICPPONB_01495	1.14e-205	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	sugar-binding domain protein
HICPPONB_01496	7.24e-126	rihA	-	-	F	ko:K01250	-	ko00000,ko01000	Inosine-uridine preferring nucleoside hydrolase
HICPPONB_01497	7.4e-255	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HICPPONB_01498	6.26e-121	-	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Psort location CytoplasmicMembrane, score 9.49
HICPPONB_01499	2.06e-118	-	-	-	P	ko:K02006,ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Psort location CytoplasmicMembrane, score 9.49
HICPPONB_01500	3.3e-102	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 9.99
HICPPONB_01501	8.96e-89	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 9.99
HICPPONB_01502	2.86e-216	-	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HICPPONB_01503	2.34e-168	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HICPPONB_01504	1.81e-152	-	-	-	K	ko:K02530	-	ko00000,ko03000	DeoR C terminal sensor domain
HICPPONB_01505	9.08e-83	-	2.7.1.202	-	GT	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HICPPONB_01506	1.1e-58	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HICPPONB_01507	1.9e-216	-	-	-	G	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase System
HICPPONB_01508	1.45e-144	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
HICPPONB_01509	9.16e-209	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
HICPPONB_01510	0.0	-	-	-	G	-	-	-	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HICPPONB_01511	1.51e-119	kdgA	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
HICPPONB_01512	4.99e-90	-	2.7.1.200, 2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770,ko:K02773	ko00051,ko00052,ko01100,ko01120,ko02060,map00051,map00052,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system
HICPPONB_01513	7.8e-52	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HICPPONB_01514	5.67e-296	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HICPPONB_01515	2.29e-274	dgoD	4.2.1.6, 4.2.1.8	-	M	ko:K01684,ko:K08323	ko00040,ko00052,ko01100,ko01120,map00040,map00052,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Mandelate racemase muconate lactonizing enzyme
HICPPONB_01516	2.55e-186	-	-	-	S	ko:K07048	-	ko00000	Phosphotriesterase family
HICPPONB_01517	2.3e-209	-	-	-	G	-	-	-	phosphotransferase system, EIIB
HICPPONB_01518	4.2e-142	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
HICPPONB_01519	4.92e-58	-	-	-	K	-	-	-	UTRA
HICPPONB_01520	9.81e-33	-	-	-	-	-	-	-	-
HICPPONB_01521	2.48e-28	-	-	-	L	ko:K07484	-	ko00000	IS66 Orf2 like protein
HICPPONB_01522	1.66e-25	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
HICPPONB_01523	0.0	yeeA	-	-	V	-	-	-	Type II restriction enzyme, methylase subunits
HICPPONB_01524	8.88e-73	-	-	-	L	-	-	-	Transposase DDE domain group 1
HICPPONB_01525	2.72e-74	-	-	-	L	-	-	-	Transposase DDE domain group 1
HICPPONB_01526	3.94e-98	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HICPPONB_01527	7.56e-77	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HICPPONB_01528	0.0	-	-	-	G	-	-	-	PTS system sorbose-specific iic component
HICPPONB_01529	3.8e-141	tal	2.2.1.2	-	H	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase/Fructose-6-phosphate aldolase
HICPPONB_01530	7.98e-193	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HICPPONB_01531	8.63e-05	-	-	-	K	ko:K20391	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
HICPPONB_01532	2.77e-33	-	-	-	G	-	-	-	PTS system fructose IIA component
HICPPONB_01533	1.24e-52	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HICPPONB_01534	7.05e-106	-	-	-	G	-	-	-	PTS system sorbose-specific iic component
HICPPONB_01535	2.89e-115	-	-	-	G	-	-	-	PTS system mannose fructose sorbose family IID component
HICPPONB_01536	1.09e-85	-	-	-	M	-	-	-	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HICPPONB_01537	5.27e-86	-	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Aldolase
HICPPONB_01538	4.16e-104	dat	2.6.1.21	-	EH	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	PFAM aminotransferase, class IV
HICPPONB_01539	1.92e-229	-	-	-	G	-	-	-	Major Facilitator Superfamily
HICPPONB_01540	3e-257	-	-	-	C	-	-	-	COG0277 FAD FMN-containing dehydrogenases
HICPPONB_01541	6.87e-137	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HICPPONB_01542	1.1e-201	-	-	-	G	-	-	-	sugar kinase
HICPPONB_01543	8.05e-105	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Domain in cystathionine beta-synthase and other proteins.
HICPPONB_01544	1.35e-80	-	-	-	U	-	-	-	Binding-protein-dependent transport system inner membrane component
HICPPONB_01545	4.42e-131	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Substrate binding domain of ABC-type glycine betaine transport system
HICPPONB_01546	4.92e-81	opuCD	-	-	U	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HICPPONB_01547	9.11e-208	-	-	-	P	-	-	-	YhfZ C-terminal domain
HICPPONB_01549	1.96e-73	-	-	-	S	-	-	-	Protein of unknown function DUF2620
HICPPONB_01550	1.66e-274	-	-	-	S	-	-	-	Protein of unknown function
HICPPONB_01551	1.19e-198	php	-	-	S	ko:K07048	-	ko00000	Phosphotriesterase family
HICPPONB_01552	2.84e-231	-	-	-	E	-	-	-	Cys/Met metabolism PLP-dependent enzyme
HICPPONB_01553	1.55e-256	-	-	-	E	-	-	-	Alanine racemase, N-terminal domain
HICPPONB_01554	9.36e-295	-	-	-	G	-	-	-	Metalloenzyme superfamily
HICPPONB_01555	9.02e-77	-	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
HICPPONB_01556	3.85e-216	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
HICPPONB_01557	5.04e-90	-	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Glycerate kinase family
HICPPONB_01558	2.35e-280	-	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HICPPONB_01559	2.67e-309	-	3.2.1.24	GH38	G	ko:K01191	ko00511,map00511	ko00000,ko00001,ko01000,ko04131	Alpha mannosidase, middle domain
HICPPONB_01560	1.87e-226	-	-	-	G	-	-	-	mannose-6-phosphate isomerase
HICPPONB_01561	1.25e-202	XK27_10120	-	-	K	-	-	-	S-adenosyl-l-methionine hydroxide adenosyltransferase
HICPPONB_01562	1.05e-127	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
HICPPONB_01563	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HICPPONB_01564	3.99e-192	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
HICPPONB_01565	2.39e-28	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HICPPONB_01566	0.0	-	-	-	K	-	-	-	Sigma-54 interaction domain
HICPPONB_01567	1.17e-95	-	-	-	G	ko:K02744	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HICPPONB_01568	3.78e-117	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HICPPONB_01569	5.53e-196	levC	-	-	M	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HICPPONB_01570	2.15e-199	levD	-	-	G	ko:K02771	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
HICPPONB_01571	9.35e-74	-	-	-	-	-	-	-	-
HICPPONB_01572	0.0	-	3.2.1.65	GH32	G	ko:K01212	ko00500,map00500	ko00000,ko00001,ko01000	Glycosyl hydrolases family 32
HICPPONB_01574	1.7e-161	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HICPPONB_01575	1.37e-172	-	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
HICPPONB_01576	5.04e-147	-	4.1.2.43	-	G	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Orotidine 5'-phosphate decarboxylase / HUMPS family
HICPPONB_01577	6.72e-125	-	5.3.1.27	-	M	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	SIS domain
HICPPONB_01578	0.0	-	2.7.1.197	-	G	ko:K02798,ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HICPPONB_01579	1.69e-278	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
HICPPONB_01580	1.07e-240	-	1.5.1.28	-	C	ko:K04940	-	ko00000,ko01000	NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain
HICPPONB_01581	1.43e-172	yxeO	-	-	E	ko:K16960,ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HICPPONB_01582	5.72e-205	-	-	-	ET	ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HICPPONB_01583	6.06e-147	ytmL	-	-	P	ko:K16958,ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HICPPONB_01584	1.04e-150	-	-	-	P	ko:K16958	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HICPPONB_01585	6.47e-304	proP	-	-	EGP	ko:K03761,ko:K03762	-	ko00000,ko02000	Sugar (and other) transporter
HICPPONB_01587	1.33e-17	-	-	-	S	-	-	-	YvrJ protein family
HICPPONB_01588	1.45e-178	-	-	-	M	-	-	-	hydrolase, family 25
HICPPONB_01589	1.68e-170	ypiA	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HICPPONB_01590	2.52e-148	-	-	-	C	-	-	-	Flavodoxin
HICPPONB_01591	5.12e-112	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HICPPONB_01592	5.69e-238	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HICPPONB_01593	7.08e-154	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HICPPONB_01594	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
HICPPONB_01595	3.06e-193	-	-	-	S	-	-	-	hydrolase
HICPPONB_01596	1.49e-58	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
HICPPONB_01597	1.15e-237	-	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
HICPPONB_01598	1.48e-109	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HICPPONB_01599	2.18e-177	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HICPPONB_01600	7.9e-196	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
HICPPONB_01601	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
HICPPONB_01602	5.07e-89	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HICPPONB_01603	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HICPPONB_01604	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HICPPONB_01605	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
HICPPONB_01607	0.0	pip	-	-	V	ko:K01421	-	ko00000	domain protein
HICPPONB_01608	1.83e-199	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HICPPONB_01609	9.68e-252	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
HICPPONB_01610	3.07e-106	-	-	-	-	-	-	-	-
HICPPONB_01611	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
HICPPONB_01612	7.24e-23	-	-	-	-	-	-	-	-
HICPPONB_01613	1.17e-129	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HICPPONB_01614	2.1e-78	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
HICPPONB_01615	4.95e-134	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
HICPPONB_01616	1.03e-242	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
HICPPONB_01617	1.01e-99	-	-	-	O	-	-	-	OsmC-like protein
HICPPONB_01620	2.13e-74	-	-	-	L	-	-	-	Exonuclease
HICPPONB_01621	4.52e-221	-	-	-	L	-	-	-	Exonuclease
HICPPONB_01622	5.14e-65	yczG	-	-	K	-	-	-	Helix-turn-helix domain
HICPPONB_01623	1.75e-256	yceJ	-	-	EGP	ko:K08221	-	ko00000,ko02000	transporter
HICPPONB_01624	8.11e-138	ydfF	-	-	K	-	-	-	Transcriptional
HICPPONB_01625	7.64e-137	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HICPPONB_01626	5.36e-215	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
HICPPONB_01627	0.0	cidC	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HICPPONB_01629	9.62e-247	pbpE	-	-	V	-	-	-	Beta-lactamase
HICPPONB_01630	3.81e-191	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
HICPPONB_01631	1.06e-183	-	-	-	H	-	-	-	Protein of unknown function (DUF1698)
HICPPONB_01632	6.65e-183	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
HICPPONB_01633	0.0	-	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	Glutamine synthetase, catalytic domain
HICPPONB_01634	2.69e-279	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
HICPPONB_01635	0.0	-	-	-	E	-	-	-	Amino acid permease
HICPPONB_01636	1.68e-98	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HICPPONB_01637	1.59e-209	-	-	-	S	-	-	-	reductase
HICPPONB_01638	6.83e-253	adh3	-	-	C	-	-	-	Zinc-binding dehydrogenase
HICPPONB_01639	7.56e-75	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HICPPONB_01640	5.62e-123	-	-	-	-	-	-	-	-
HICPPONB_01641	0.0	-	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HICPPONB_01642	2.46e-72	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HICPPONB_01643	1.32e-291	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HICPPONB_01644	6.82e-66	licB2	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HICPPONB_01645	0.0	-	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
HICPPONB_01646	7.58e-134	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
HICPPONB_01647	0.0	yvcC	-	-	M	-	-	-	Cna protein B-type domain
HICPPONB_01648	2.37e-161	-	-	-	M	-	-	-	domain protein
HICPPONB_01649	1.25e-236	-	-	-	M	-	-	-	LPXTG cell wall anchor motif
HICPPONB_01650	1.75e-255	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HICPPONB_01651	3.22e-162	XK27_12140	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HICPPONB_01652	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HICPPONB_01653	4.23e-152	-	-	-	K	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
HICPPONB_01654	5.71e-250	-	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HICPPONB_01655	9.49e-172	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
HICPPONB_01656	1.57e-245	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HICPPONB_01657	5.27e-107	-	-	-	-	-	-	-	-
HICPPONB_01658	0.0	prtP	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HICPPONB_01659	0.0	prtP	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HICPPONB_01660	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
HICPPONB_01661	0.0	ycaM	-	-	E	-	-	-	amino acid
HICPPONB_01662	1.66e-117	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
HICPPONB_01663	1.93e-210	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
HICPPONB_01664	4.66e-206	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
HICPPONB_01665	1.26e-180	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HICPPONB_01666	1.53e-211	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HICPPONB_01667	7.38e-274	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HICPPONB_01668	4.06e-213	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HICPPONB_01669	2.26e-205	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
HICPPONB_01670	2.2e-222	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HICPPONB_01671	1.19e-23	-	-	-	-	-	-	-	-
HICPPONB_01673	6.18e-283	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HICPPONB_01678	4.87e-173	-	-	-	-	-	-	-	-
HICPPONB_01679	2.33e-25	-	-	-	E	-	-	-	Zn peptidase
HICPPONB_01680	1.51e-80	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HICPPONB_01683	4.03e-202	ps305	-	-	S	-	-	-	Protein of unknown function (Hypoth_ymh)
HICPPONB_01684	2.23e-179	-	-	-	S	-	-	-	ORF6N domain
HICPPONB_01686	2.77e-58	-	-	-	S	-	-	-	Domain of unknown function (DUF1883)
HICPPONB_01691	7.76e-181	-	-	-	L	-	-	-	Helix-turn-helix domain
HICPPONB_01692	2.94e-198	pi346	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
HICPPONB_01694	3.84e-94	-	-	-	-	-	-	-	-
HICPPONB_01695	1.24e-08	-	-	-	-	-	-	-	-
HICPPONB_01696	5.18e-149	-	-	-	-	-	-	-	-
HICPPONB_01699	3.92e-104	-	-	-	-	-	-	-	-
HICPPONB_01701	2.43e-29	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
HICPPONB_01702	3.21e-72	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
HICPPONB_01703	0.000324	-	-	-	S	-	-	-	CsbD-like
HICPPONB_01704	9.55e-205	-	-	-	-	-	-	-	-
HICPPONB_01705	8.29e-74	-	-	-	-	-	-	-	-
HICPPONB_01706	2.11e-69	-	-	-	L	ko:K07483	-	ko00000	4.5 Transposon and IS
HICPPONB_01707	2.5e-174	-	-	-	L	-	-	-	Helix-turn-helix domain
HICPPONB_01708	1.66e-213	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HICPPONB_01709	1.95e-200	-	-	-	L	ko:K07497	-	ko00000	4.5 Transposon and IS
HICPPONB_01714	6.78e-42	-	-	-	-	-	-	-	-
HICPPONB_01715	2.43e-283	-	-	-	-	-	-	-	-
HICPPONB_01716	8.45e-311	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HICPPONB_01719	0.0	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	TraM recognition site of TraD and TraG
HICPPONB_01720	0.0	-	-	-	S	-	-	-	domain, Protein
HICPPONB_01722	3.2e-137	-	-	-	-	-	-	-	-
HICPPONB_01723	0.0	-	-	-	S	-	-	-	COG0433 Predicted ATPase
HICPPONB_01724	1.36e-241	-	-	-	M	ko:K21471,ko:K21472	-	ko00000,ko01000,ko01002,ko01011	cysteine-type peptidase activity
HICPPONB_01731	5.78e-287	-	-	-	S	-	-	-	COG0790 FOG TPR repeat, SEL1 subfamily
HICPPONB_01733	0.0	-	-	-	L	-	-	-	Protein of unknown function (DUF3991)
HICPPONB_01734	2.08e-84	-	-	-	-	-	-	-	-
HICPPONB_01735	2.97e-24	-	-	-	-	-	-	-	-
HICPPONB_01736	1.03e-91	-	-	-	-	-	-	-	-
HICPPONB_01738	2.01e-102	-	-	-	-	-	-	-	-
HICPPONB_01739	2.22e-200	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HICPPONB_01741	1.34e-104	-	-	-	L	-	-	-	Transposase DDE domain
HICPPONB_01742	5.7e-65	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HICPPONB_01743	0.0	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
HICPPONB_01744	1.77e-81	-	-	-	M	-	-	-	Cna protein B-type domain
HICPPONB_01745	4.21e-212	-	-	-	P	-	-	-	CorA-like Mg2+ transporter protein
HICPPONB_01746	4.49e-74	-	-	-	L	-	-	-	Transposase DDE domain
HICPPONB_01747	2.15e-77	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HICPPONB_01748	4.82e-83	-	-	-	L	-	-	-	Transposase DDE domain
HICPPONB_01750	0.0	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
HICPPONB_01751	4.09e-131	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HICPPONB_01752	5.55e-70	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HICPPONB_01753	2.15e-77	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HICPPONB_01754	1.42e-69	-	-	-	L	-	-	-	Transposase DDE domain
HICPPONB_01755	7.26e-208	lacT	-	-	K	ko:K02531	-	ko00000,ko03000	PRD domain
HICPPONB_01756	0.0	lacE	2.7.1.207	-	G	ko:K02787,ko:K02788	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system, EIIC
HICPPONB_01757	0.0	lacG	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HICPPONB_01758	5.36e-67	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HICPPONB_01759	9.14e-41	-	-	-	S	-	-	-	Transglycosylase associated protein
HICPPONB_01760	7.06e-114	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HICPPONB_01761	1.28e-33	-	-	-	S	-	-	-	Small integral membrane protein (DUF2273)
HICPPONB_01762	3.76e-121	-	-	-	-	-	-	-	-
HICPPONB_01763	3.33e-133	tnpR	-	-	L	-	-	-	Resolvase, N terminal domain
HICPPONB_01764	3.3e-315	xylP	-	-	G	-	-	-	MFS/sugar transport protein
HICPPONB_01765	7.69e-134	-	-	-	-	-	-	-	-
HICPPONB_01766	0.0	-	-	-	M	-	-	-	domain protein
HICPPONB_01767	8.62e-309	-	-	-	-	-	-	-	-
HICPPONB_01768	0.0	-	-	-	M	-	-	-	Cna protein B-type domain
HICPPONB_01769	1.56e-189	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HICPPONB_01770	1.14e-294	-	-	-	S	-	-	-	Membrane
HICPPONB_01771	1.28e-55	-	-	-	-	-	-	-	-
HICPPONB_01773	3.82e-191	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HICPPONB_01774	5.68e-280	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HICPPONB_01775	8.53e-287	-	-	-	EGP	-	-	-	Transmembrane secretion effector
HICPPONB_01776	3.53e-52	-	-	-	-	-	-	-	-
HICPPONB_01777	1.5e-44	-	-	-	-	-	-	-	-
HICPPONB_01779	1.59e-28	yhjA	-	-	K	-	-	-	CsbD-like
HICPPONB_01780	2.84e-263	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HICPPONB_01781	5.25e-61	-	-	-	-	-	-	-	-
HICPPONB_01782	4.71e-263	-	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
HICPPONB_01784	3.28e-156	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HICPPONB_01785	8.84e-120	ccpN	-	-	K	-	-	-	Domain in cystathionine beta-synthase and other proteins.
HICPPONB_01794	2.5e-104	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
HICPPONB_01795	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HICPPONB_01796	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HICPPONB_01797	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HICPPONB_01798	2.22e-48	-	3.4.23.43	-	-	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	-
HICPPONB_01799	0.0	-	-	-	M	-	-	-	domain protein
HICPPONB_01800	1.11e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HICPPONB_01801	2.06e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HICPPONB_01802	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HICPPONB_01803	1.18e-255	-	-	-	K	-	-	-	WYL domain
HICPPONB_01804	2.38e-138	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	C-terminal domain of 1-Cys peroxiredoxin
HICPPONB_01805	3.63e-90	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
HICPPONB_01806	4.46e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HICPPONB_01807	4.01e-146	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HICPPONB_01808	1.98e-140	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HICPPONB_01809	1.02e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HICPPONB_01810	1.03e-200	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HICPPONB_01811	5.26e-63	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HICPPONB_01812	4.5e-73	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HICPPONB_01813	6.88e-152	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HICPPONB_01814	1.38e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HICPPONB_01815	3.55e-33	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HICPPONB_01816	5.93e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HICPPONB_01817	1.73e-77	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HICPPONB_01818	4.1e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HICPPONB_01819	8.67e-124	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HICPPONB_01820	1.32e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HICPPONB_01821	2.61e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HICPPONB_01822	1.62e-76	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HICPPONB_01823	5.74e-109	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HICPPONB_01824	2.6e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HICPPONB_01825	4.07e-92	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HICPPONB_01826	2.01e-303	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HICPPONB_01827	1.29e-155	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HICPPONB_01828	4.15e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HICPPONB_01829	6.38e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
HICPPONB_01830	5.37e-76	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HICPPONB_01831	3.82e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HICPPONB_01832	1.26e-218	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HICPPONB_01833	5.46e-81	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HICPPONB_01834	6.72e-140	-	-	-	-	-	-	-	-
HICPPONB_01835	1.15e-197	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HICPPONB_01836	1.92e-202	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HICPPONB_01837	1.13e-181	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HICPPONB_01838	1.39e-178	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HICPPONB_01839	2.18e-169	tipA	-	-	K	-	-	-	TipAS antibiotic-recognition domain
HICPPONB_01840	1.5e-44	-	-	-	-	-	-	-	-
HICPPONB_01841	7.4e-164	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HICPPONB_01842	2.39e-234	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HICPPONB_01843	4.89e-139	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HICPPONB_01844	2.98e-104	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HICPPONB_01845	8.98e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HICPPONB_01846	1.51e-73	-	-	-	-	-	-	-	-
HICPPONB_01847	1.44e-142	-	-	-	-	-	-	-	-
HICPPONB_01848	1.15e-79	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
HICPPONB_01850	3.51e-169	-	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HICPPONB_01851	1.22e-172	XK27_06945	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HICPPONB_01852	2.54e-171	XK27_06950	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HICPPONB_01853	3.98e-190	ssuC	-	-	U	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HICPPONB_01854	1.17e-154	ssuB	-	-	P	ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HICPPONB_01855	3.03e-296	-	-	-	I	-	-	-	Acyltransferase family
HICPPONB_01856	0.0	-	6.2.1.48	-	IQ	ko:K02182	-	ko00000,ko01000	AMP-binding enzyme C-terminal domain
HICPPONB_01857	5.18e-224	ssuA	-	-	P	ko:K02051,ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	NMT1-like family
HICPPONB_01858	1.97e-188	ptxC	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HICPPONB_01859	1e-173	phnB	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HICPPONB_01860	1.49e-178	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HICPPONB_01861	1.99e-212	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
HICPPONB_01862	8.17e-285	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
HICPPONB_01863	1.06e-280	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HICPPONB_01866	7.54e-90	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HICPPONB_01867	3.56e-68	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HICPPONB_01869	1.28e-95	-	-	-	-	-	-	-	-
HICPPONB_01870	2.1e-27	-	-	-	-	-	-	-	-
HICPPONB_01871	1.26e-212	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HICPPONB_01872	0.0	-	-	-	M	-	-	-	domain protein
HICPPONB_01873	2.87e-101	-	-	-	-	-	-	-	-
HICPPONB_01874	6.65e-114	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
HICPPONB_01875	2.83e-152	-	-	-	GM	-	-	-	NmrA-like family
HICPPONB_01876	6.75e-215	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HICPPONB_01877	6.85e-55	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HICPPONB_01878	0.0	aldA	1.2.1.21, 1.2.1.22	-	C	ko:K07248	ko00620,ko00630,ko01120,map00620,map00630,map01120	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family
HICPPONB_01879	3.38e-170	-	3.6.3.35	-	P	ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HICPPONB_01880	5.89e-185	mtsB	-	-	U	ko:K19972,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HICPPONB_01881	6.58e-226	mntA	-	-	P	ko:K19975,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HICPPONB_01882	1.23e-69	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
HICPPONB_01883	2.22e-144	-	-	-	P	-	-	-	Cation efflux family
HICPPONB_01884	8.86e-35	-	-	-	-	-	-	-	-
HICPPONB_01885	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
HICPPONB_01886	8.91e-306	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HICPPONB_01887	9.77e-74	-	-	-	-	-	-	-	-
HICPPONB_01888	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HICPPONB_01889	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HICPPONB_01890	6.42e-28	-	-	-	-	-	-	-	-
HICPPONB_01891	6.31e-173	-	-	-	-	-	-	-	-
HICPPONB_01892	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HICPPONB_01893	2.12e-273	yqiG	-	-	C	-	-	-	Oxidoreductase
HICPPONB_01894	3.51e-166	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HICPPONB_01895	4.15e-231	ydhF	-	-	S	-	-	-	Aldo keto reductase
HICPPONB_01899	1.78e-134	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HICPPONB_01900	1.96e-71	-	-	-	S	-	-	-	Enterocin A Immunity
HICPPONB_01902	1.61e-74	-	-	-	-	-	-	-	-
HICPPONB_01904	3.08e-184	-	-	-	S	-	-	-	CAAX protease self-immunity
HICPPONB_01908	1.81e-15	-	-	-	-	-	-	-	-
HICPPONB_01914	4.43e-181	plnD	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HICPPONB_01915	6.16e-117	comD	2.7.13.3	-	T	ko:K07706,ko:K12294	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HICPPONB_01917	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HICPPONB_01918	1.55e-307	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
HICPPONB_01919	4.01e-80	-	-	-	-	-	-	-	-
HICPPONB_01921	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
HICPPONB_01922	2.35e-57	spiA	-	-	K	-	-	-	TRANSCRIPTIONal
HICPPONB_01923	2.22e-60	-	-	-	S	-	-	-	Enterocin A Immunity
HICPPONB_01924	6.69e-61	-	-	-	S	-	-	-	Enterocin A Immunity
HICPPONB_01925	2.99e-176	-	-	-	-	-	-	-	-
HICPPONB_01926	8.35e-82	-	-	-	-	-	-	-	-
HICPPONB_01927	5.88e-72	padR	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
HICPPONB_01928	4.63e-98	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HICPPONB_01929	5.7e-262	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
HICPPONB_01930	2.67e-293	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HICPPONB_01931	1.05e-131	-	-	-	-	-	-	-	-
HICPPONB_01932	8.93e-47	-	-	-	-	-	-	-	-
HICPPONB_01933	2.39e-83	-	-	-	L	-	-	-	Transposase DDE domain
HICPPONB_01934	2.15e-77	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HICPPONB_01935	6.3e-222	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HICPPONB_01936	1.24e-25	-	-	-	L	ko:K07483	-	ko00000	Homeodomain-like domain
HICPPONB_01937	7.02e-218	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HICPPONB_01938	6.05e-264	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HICPPONB_01939	0.0	malL	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HICPPONB_01940	5.08e-208	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HICPPONB_01942	4.4e-47	-	-	-	U	-	-	-	Preprotein translocase subunit SecB
HICPPONB_01943	5.74e-207	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HICPPONB_01944	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HICPPONB_01945	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HICPPONB_01946	2.07e-250	-	-	-	S	-	-	-	Membrane
HICPPONB_01947	3.35e-84	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HICPPONB_01948	8.39e-21	-	-	-	L	ko:K07483	-	ko00000	Transposase and inactivated derivatives
HICPPONB_01949	8.06e-232	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HICPPONB_01950	1.04e-271	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HICPPONB_01951	3.96e-185	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HICPPONB_01952	3.91e-155	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HICPPONB_01953	5.74e-47	-	-	-	-	-	-	-	-
HICPPONB_01954	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HICPPONB_01955	2.68e-150	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HICPPONB_01956	1.73e-225	-	-	-	S	-	-	-	Cell surface protein
HICPPONB_01957	1.78e-58	-	-	-	-	-	-	-	-
HICPPONB_01958	2.49e-244	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
HICPPONB_01959	3.36e-154	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HICPPONB_01960	6.33e-74	-	-	-	-	-	-	-	-
HICPPONB_01961	3.5e-138	-	-	-	N	-	-	-	WxL domain surface cell wall-binding
HICPPONB_01962	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
HICPPONB_01963	6.94e-225	yicL	-	-	EG	-	-	-	EamA-like transporter family
HICPPONB_01964	0.0	-	-	-	-	-	-	-	-
HICPPONB_01965	1.44e-184	CcmA5	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HICPPONB_01966	4.75e-113	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
HICPPONB_01967	1.83e-192	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
HICPPONB_01968	7.88e-211	metF	1.5.1.20	-	C	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
HICPPONB_01969	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HICPPONB_01973	1.41e-46	-	-	-	S	-	-	-	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HICPPONB_01974	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HICPPONB_01975	0.0	-	-	-	V	ko:K06147,ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HICPPONB_01976	3.34e-286	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
HICPPONB_01977	1.56e-166	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
HICPPONB_01978	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HICPPONB_01979	0.0	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HICPPONB_01980	1.51e-283	sstT	-	-	U	ko:K07862	-	ko00000,ko02000	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HICPPONB_01981	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
HICPPONB_01982	1.13e-221	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	lactate/malate dehydrogenase, alpha/beta C-terminal domain
HICPPONB_01983	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HICPPONB_01984	3.08e-43	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
HICPPONB_01985	5.54e-85	-	-	-	-	-	-	-	-
HICPPONB_01986	1.37e-99	-	-	-	O	-	-	-	OsmC-like protein
HICPPONB_01987	0.0	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
HICPPONB_01988	2.73e-147	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
HICPPONB_01990	1.92e-202	-	-	-	S	-	-	-	Aldo/keto reductase family
HICPPONB_01991	9.04e-317	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HICPPONB_01992	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF3800)
HICPPONB_01993	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HICPPONB_01994	2.72e-78	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HICPPONB_01995	4.89e-95	-	-	-	K	-	-	-	LytTr DNA-binding domain
HICPPONB_01996	2.19e-191	-	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
HICPPONB_01997	3.89e-210	-	-	-	V	ko:K01990,ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HICPPONB_01998	5.05e-187	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HICPPONB_01999	1.57e-158	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
HICPPONB_02000	1.06e-69	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
HICPPONB_02001	2.05e-203	-	-	-	C	-	-	-	nadph quinone reductase
HICPPONB_02002	3.8e-316	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
HICPPONB_02003	3.97e-227	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
HICPPONB_02004	2.59e-153	yqgG	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
HICPPONB_02005	2.3e-146	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
HICPPONB_02007	1.11e-32	-	-	-	-	-	-	-	-
HICPPONB_02009	8.25e-05	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
HICPPONB_02010	1.62e-159	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	proteolysis
HICPPONB_02011	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HICPPONB_02012	0.0	-	-	-	L	-	-	-	ATPase domain of DNA mismatch repair MUTS family
HICPPONB_02013	1.48e-144	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
HICPPONB_02014	4.49e-169	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HICPPONB_02015	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
HICPPONB_02016	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HICPPONB_02017	4.38e-174	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HICPPONB_02018	1.35e-281	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HICPPONB_02019	4.24e-247	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HICPPONB_02020	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HICPPONB_02021	6.88e-218	msmR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HICPPONB_02022	4.79e-251	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HICPPONB_02025	1.37e-110	-	2.7.1.204	-	G	ko:K20112	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HICPPONB_02026	2.68e-67	-	2.7.1.204	-	G	ko:K20113	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HICPPONB_02027	0.0	gatC	-	-	G	ko:K20114	ko02060,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HICPPONB_02028	9.83e-37	-	-	-	-	-	-	-	-
HICPPONB_02029	1.75e-157	-	-	-	S	-	-	-	Domain of unknown function (DUF4867)
HICPPONB_02030	1.95e-222	lacC	2.7.1.144	-	H	ko:K00917	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
HICPPONB_02031	2.95e-239	lacD	4.1.2.40	-	G	ko:K01635	ko00052,ko01100,ko02024,map00052,map01100,map02024	ko00000,ko00001,ko01000	Belongs to the aldolase LacD family
HICPPONB_02032	4.53e-122	lacB	5.3.1.26	-	G	ko:K01819	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Ribose/Galactose Isomerase
HICPPONB_02033	3.58e-96	lacA	5.3.1.26	-	G	ko:K01819	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Ribose/Galactose Isomerase
HICPPONB_02034	4.13e-181	-	-	-	K	ko:K02530	-	ko00000,ko03000	DeoR C terminal sensor domain
HICPPONB_02035	3.73e-150	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
HICPPONB_02036	7.93e-271	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HICPPONB_02037	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
HICPPONB_02038	6.8e-21	-	-	-	-	-	-	-	-
HICPPONB_02039	7.42e-112	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HICPPONB_02041	1.37e-270	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
HICPPONB_02042	5.49e-192	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HICPPONB_02043	1.5e-156	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
HICPPONB_02045	8.69e-112	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HICPPONB_02046	1.11e-152	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HICPPONB_02047	3.87e-198	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HICPPONB_02048	1.94e-251	-	-	-	-	-	-	-	-
HICPPONB_02050	3.99e-149	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HICPPONB_02051	0.0	bglB	3.2.1.21, 3.2.1.52	GH3	G	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	ko00000,ko00001,ko00002,ko01000	hydrolase, family 3
HICPPONB_02052	2.62e-214	XK27_00670	-	-	S	ko:K01989,ko:K05832	-	ko00000,ko00002,ko02000	ABC transporter substrate binding protein
HICPPONB_02053	1.19e-212	XK27_00670	-	-	S	ko:K01989,ko:K05832	-	ko00000,ko00002,ko02000	ABC transporter
HICPPONB_02054	6.83e-208	WQ51_06230	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HICPPONB_02055	3.37e-180	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HICPPONB_02056	1.95e-221	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
HICPPONB_02057	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
HICPPONB_02058	8.07e-233	ykcC	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyl transferase family 2
HICPPONB_02059	0.0	ykcB	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
HICPPONB_02060	3.08e-93	-	-	-	S	-	-	-	GtrA-like protein
HICPPONB_02061	9.21e-158	ciaR	-	-	K	ko:K14983	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	cheY-homologous receiver domain
HICPPONB_02062	3.66e-310	ciaH	2.7.13.3	-	T	ko:K14982	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
HICPPONB_02063	2.42e-88	-	-	-	S	-	-	-	Belongs to the HesB IscA family
HICPPONB_02064	0.0	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
HICPPONB_02065	1.12e-208	-	-	-	S	-	-	-	KR domain
HICPPONB_02066	4.04e-204	adc	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
HICPPONB_02067	4.87e-156	ydgI	-	-	C	-	-	-	Nitroreductase family
HICPPONB_02068	1.84e-262	lldD	1.13.12.4	-	C	ko:K00467	ko00620,map00620	ko00000,ko00001,ko01000	IMP dehydrogenase / GMP reductase domain
HICPPONB_02071	1.86e-244	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
HICPPONB_02072	1.17e-77	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
HICPPONB_02073	2.7e-62	ygbF	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
HICPPONB_02074	4.91e-55	-	-	-	-	-	-	-	-
HICPPONB_02075	1.93e-243	-	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HICPPONB_02077	1.32e-71	-	-	-	-	-	-	-	-
HICPPONB_02078	1.79e-104	-	-	-	-	-	-	-	-
HICPPONB_02079	5.77e-267	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
HICPPONB_02080	1.58e-33	-	-	-	-	-	-	-	-
HICPPONB_02081	9.86e-146	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HICPPONB_02082	3.6e-59	-	-	-	-	-	-	-	-
HICPPONB_02083	5.96e-214	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
HICPPONB_02084	2.13e-116	-	-	-	S	-	-	-	Flavin reductase like domain
HICPPONB_02085	3.4e-91	-	-	-	-	-	-	-	-
HICPPONB_02086	1.09e-129	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HICPPONB_02087	1.7e-81	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
HICPPONB_02088	7.36e-222	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HICPPONB_02089	2.07e-202	mleR	-	-	K	-	-	-	LysR family
HICPPONB_02090	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
HICPPONB_02091	3.58e-217	mleP	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
HICPPONB_02092	8.23e-117	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HICPPONB_02093	3.08e-110	-	-	-	C	-	-	-	FMN binding
HICPPONB_02094	2.19e-222	-	-	-	K	ko:K20373,ko:K20374	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
HICPPONB_02095	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
HICPPONB_02096	0.0	pepF	-	-	E	-	-	-	Oligopeptidase F
HICPPONB_02097	3.86e-78	-	-	-	-	-	-	-	-
HICPPONB_02098	5.42e-170	-	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HICPPONB_02099	4.06e-107	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
HICPPONB_02100	0.0	yfgQ	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
HICPPONB_02101	2.59e-229	-	3.4.11.5	-	I	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	carboxylic ester hydrolase activity
HICPPONB_02102	1.69e-58	-	-	-	-	-	-	-	-
HICPPONB_02103	2.83e-121	-	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HICPPONB_02104	3.96e-256	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HICPPONB_02105	7.46e-157	XK27_05175	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
HICPPONB_02106	2.24e-101	-	-	-	K	-	-	-	Transcriptional regulator
HICPPONB_02107	2.4e-231	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HICPPONB_02108	1.56e-108	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
HICPPONB_02109	4.36e-200	dkgB	-	-	S	-	-	-	reductase
HICPPONB_02110	4.76e-201	-	-	-	-	-	-	-	-
HICPPONB_02111	1.02e-197	-	-	-	S	-	-	-	Alpha beta hydrolase
HICPPONB_02112	7.76e-152	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
HICPPONB_02113	4.49e-97	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
HICPPONB_02114	5.92e-284	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
HICPPONB_02115	1.69e-112	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HICPPONB_02116	8.05e-88	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HICPPONB_02117	6.1e-27	-	-	-	-	-	-	-	-
HICPPONB_02118	1.72e-64	-	-	-	-	-	-	-	-
HICPPONB_02119	8.6e-113	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HICPPONB_02121	1.26e-142	-	-	-	S	-	-	-	Flavodoxin-like fold
HICPPONB_02122	7.57e-122	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HICPPONB_02123	7.18e-191	hutG	3.5.3.8	-	E	ko:K01479	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	N-formylglutamate amidohydrolase
HICPPONB_02124	6.77e-71	XK27_08430	-	-	S	-	-	-	Staphylococcal protein of unknown function (DUF960)
HICPPONB_02125	2.35e-117	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HICPPONB_02126	1.7e-123	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HICPPONB_02127	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HICPPONB_02128	8.85e-76	-	-	-	-	-	-	-	-
HICPPONB_02129	5.87e-109	-	-	-	S	-	-	-	ASCH
HICPPONB_02130	1.32e-33	-	-	-	-	-	-	-	-
HICPPONB_02131	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HICPPONB_02132	6.37e-259	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HICPPONB_02133	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HICPPONB_02134	3.18e-127	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HICPPONB_02135	1.6e-246	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HICPPONB_02136	8.81e-288	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
HICPPONB_02137	1.28e-224	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HICPPONB_02138	2.83e-213	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HICPPONB_02139	4.59e-176	terC	-	-	P	-	-	-	Integral membrane protein TerC family
HICPPONB_02140	1.27e-76	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HICPPONB_02141	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HICPPONB_02142	1.29e-60	ylxQ	-	-	J	-	-	-	ribosomal protein
HICPPONB_02143	9.63e-61	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
HICPPONB_02144	4.13e-277	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HICPPONB_02145	1.33e-110	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HICPPONB_02146	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HICPPONB_02147	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HICPPONB_02148	3.52e-292	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HICPPONB_02149	7.66e-179	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HICPPONB_02150	2.14e-179	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HICPPONB_02151	4.96e-121	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HICPPONB_02152	5.86e-167	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HICPPONB_02153	1.63e-200	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HICPPONB_02154	1.18e-182	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HICPPONB_02155	4.43e-60	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
HICPPONB_02156	8.33e-168	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
HICPPONB_02157	9.87e-159	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
HICPPONB_02158	3.06e-289	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
HICPPONB_02159	4.28e-181	yejC	-	-	S	-	-	-	Protein of unknown function (DUF1003)
HICPPONB_02160	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HICPPONB_02161	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HICPPONB_02162	1.39e-40	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
HICPPONB_02163	2.84e-48	ynzC	-	-	S	-	-	-	UPF0291 protein
HICPPONB_02164	3.28e-28	-	-	-	-	-	-	-	-
HICPPONB_02165	2e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HICPPONB_02166	1.76e-185	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HICPPONB_02167	1.25e-119	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HICPPONB_02168	1.55e-51	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HICPPONB_02169	2.97e-59	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HICPPONB_02170	2.16e-303	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HICPPONB_02171	1.26e-75	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HICPPONB_02173	7.91e-70	-	-	-	-	-	-	-	-
HICPPONB_02174	2.49e-230	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HICPPONB_02175	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HICPPONB_02176	8.02e-161	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HICPPONB_02177	0.0	oppA1	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HICPPONB_02178	1.16e-193	oppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HICPPONB_02179	3.2e-216	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HICPPONB_02180	1.62e-228	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HICPPONB_02181	4.24e-247	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HICPPONB_02182	3.21e-49	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HICPPONB_02183	1.92e-239	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HICPPONB_02184	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HICPPONB_02185	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
HICPPONB_02186	5.83e-75	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HICPPONB_02187	2.29e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HICPPONB_02188	1.25e-164	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HICPPONB_02189	4.16e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HICPPONB_02190	1.38e-221	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HICPPONB_02191	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HICPPONB_02192	5.22e-174	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HICPPONB_02193	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HICPPONB_02194	1.96e-225	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HICPPONB_02195	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HICPPONB_02196	5.63e-275	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HICPPONB_02197	1.77e-47	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HICPPONB_02198	2.52e-148	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HICPPONB_02199	1.65e-117	-	-	-	S	ko:K07001	-	ko00000	Patatin-like phospholipase
HICPPONB_02200	1.57e-65	-	-	-	-	-	-	-	-
HICPPONB_02202	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HICPPONB_02203	4.19e-96	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HICPPONB_02204	8.09e-197	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HICPPONB_02205	1.49e-188	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HICPPONB_02206	1.42e-43	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HICPPONB_02207	3.66e-294	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HICPPONB_02208	1.82e-192	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HICPPONB_02209	1.85e-85	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HICPPONB_02210	7.76e-98	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
HICPPONB_02211	6.06e-132	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HICPPONB_02213	5.05e-258	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HICPPONB_02214	1.6e-63	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HICPPONB_02215	1.77e-74	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
HICPPONB_02216	5.83e-67	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HICPPONB_02217	1.17e-16	-	-	-	-	-	-	-	-
HICPPONB_02220	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HICPPONB_02221	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HICPPONB_02222	1.32e-80	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
HICPPONB_02223	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
HICPPONB_02224	1.93e-303	ynbB	-	-	P	-	-	-	aluminum resistance
HICPPONB_02225	6.3e-222	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HICPPONB_02226	3.33e-35	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
HICPPONB_02227	1.59e-95	yqhL	-	-	P	-	-	-	Rhodanese-like protein
HICPPONB_02228	1.13e-228	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
HICPPONB_02229	2.28e-53	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
HICPPONB_02230	1.33e-157	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
HICPPONB_02231	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HICPPONB_02232	0.0	-	-	-	S	-	-	-	Bacterial membrane protein YfhO
HICPPONB_02233	1.15e-71	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
HICPPONB_02234	2.04e-149	vraR	-	-	K	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
HICPPONB_02235	1.33e-231	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HICPPONB_02236	1.1e-164	yvqF	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
HICPPONB_02237	1.05e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HICPPONB_02238	3.43e-148	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HICPPONB_02239	7.4e-265	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HICPPONB_02240	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HICPPONB_02241	3.55e-259	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HICPPONB_02242	1.2e-87	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HICPPONB_02243	3.09e-122	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HICPPONB_02244	4.47e-178	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HICPPONB_02245	4.17e-60	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HICPPONB_02246	2.58e-228	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HICPPONB_02247	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HICPPONB_02248	1.01e-157	csrR	-	-	K	-	-	-	response regulator
HICPPONB_02249	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HICPPONB_02250	9.91e-53	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HICPPONB_02251	1.09e-127	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HICPPONB_02252	3.92e-269	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HICPPONB_02253	9.8e-178	yccK	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
HICPPONB_02254	1.18e-78	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HICPPONB_02255	3.21e-142	yqeK	-	-	H	-	-	-	Hydrolase, HD family
HICPPONB_02256	2.72e-157	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HICPPONB_02257	3.95e-65	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
HICPPONB_02258	2.04e-260	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
HICPPONB_02259	6.63e-127	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
HICPPONB_02260	9.68e-221	ykcA	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HICPPONB_02261	4.55e-242	mhqA_2	-	-	E	ko:K15975	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HICPPONB_02262	2.14e-157	mhqD	-	-	S	ko:K06999	-	ko00000	Dienelactone hydrolase family
HICPPONB_02263	4.31e-231	-	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
HICPPONB_02264	2.37e-129	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HICPPONB_02265	1.02e-74	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HICPPONB_02266	1.13e-36	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HICPPONB_02267	7.46e-101	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HICPPONB_02268	2.7e-166	-	-	-	S	-	-	-	SseB protein N-terminal domain
HICPPONB_02269	5.3e-70	-	-	-	-	-	-	-	-
HICPPONB_02270	5.18e-134	yrgI	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Histidine phosphatase superfamily (branch 1)
HICPPONB_02271	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HICPPONB_02273	2.02e-219	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HICPPONB_02274	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
HICPPONB_02275	2.06e-103	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HICPPONB_02276	1.34e-130	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HICPPONB_02277	9.18e-206	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HICPPONB_02278	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HICPPONB_02279	4.93e-153	ybhL	-	-	S	ko:K06890	-	ko00000	Inhibitor of apoptosis-promoting Bax1
HICPPONB_02280	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HICPPONB_02281	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HICPPONB_02282	3.17e-149	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HICPPONB_02283	5.32e-73	ytpP	-	-	CO	-	-	-	Thioredoxin
HICPPONB_02285	6.68e-156	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HICPPONB_02286	3.71e-188	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
HICPPONB_02287	3.38e-274	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HICPPONB_02288	2.8e-171	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HICPPONB_02289	1.67e-99	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
HICPPONB_02290	2.35e-80	-	-	-	S	-	-	-	YtxH-like protein
HICPPONB_02291	5.26e-205	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HICPPONB_02292	8.42e-232	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
HICPPONB_02293	1.03e-72	-	-	-	S	-	-	-	Control of competence regulator ComK, YlbF/YmcA
HICPPONB_02294	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HICPPONB_02295	1.3e-198	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HICPPONB_02296	3.31e-98	argR1	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HICPPONB_02297	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HICPPONB_02299	1.97e-88	-	-	-	-	-	-	-	-
HICPPONB_02300	9.55e-31	-	-	-	-	-	-	-	-
HICPPONB_02301	3.67e-227	pyrD	1.3.5.2, 1.3.98.1	-	F	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate
HICPPONB_02302	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
HICPPONB_02303	1.44e-157	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HICPPONB_02304	1.13e-89	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HICPPONB_02305	3.83e-175	yhfI	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HICPPONB_02306	7.88e-121	traP	1.14.99.57, 6.2.1.3	-	S	ko:K01897,ko:K21481	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	heme oxygenase (decyclizing) activity
HICPPONB_02307	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
HICPPONB_02308	1.14e-177	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HICPPONB_02309	1.57e-159	rrp1	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
HICPPONB_02310	1.21e-266	-	-	-	T	ko:K19168	-	ko00000,ko02048	His Kinase A (phosphoacceptor) domain
HICPPONB_02311	1.54e-141	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HICPPONB_02312	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5	-	P	ko:K01533,ko:K01534	-	ko00000,ko01000	P-type ATPase
HICPPONB_02313	1.17e-100	copR	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
HICPPONB_02314	1.57e-299	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HICPPONB_02315	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HICPPONB_02316	5.57e-129	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HICPPONB_02317	1.98e-234	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HICPPONB_02318	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HICPPONB_02319	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HICPPONB_02320	3.42e-165	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HICPPONB_02321	8.48e-55	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HICPPONB_02322	1.82e-169	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HICPPONB_02323	9.63e-271	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HICPPONB_02324	2.66e-102	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HICPPONB_02325	3.87e-135	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
HICPPONB_02326	0.0	iolT	-	-	EGP	ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HICPPONB_02327	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HICPPONB_02328	1.02e-51	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
HICPPONB_02329	9.5e-39	-	-	-	-	-	-	-	-
HICPPONB_02330	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HICPPONB_02331	3.36e-61	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
HICPPONB_02333	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HICPPONB_02334	4.82e-310	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
HICPPONB_02335	4.17e-262	yueF	-	-	S	-	-	-	AI-2E family transporter
HICPPONB_02336	4.61e-97	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HICPPONB_02337	3.88e-123	-	-	-	-	-	-	-	-
HICPPONB_02338	1.1e-134	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
HICPPONB_02339	6.84e-183	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
HICPPONB_02340	0.0	frvR	-	-	K	ko:K02538,ko:K03483,ko:K09685,ko:K18531	-	ko00000,ko03000	transcriptional antiterminator
HICPPONB_02341	6.46e-83	-	-	-	-	-	-	-	-
HICPPONB_02342	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HICPPONB_02343	1.68e-103	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
HICPPONB_02344	2.13e-172	-	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
HICPPONB_02345	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HICPPONB_02346	0.0	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HICPPONB_02347	2.36e-111	-	-	-	-	-	-	-	-
HICPPONB_02348	7.89e-66	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HICPPONB_02349	6.27e-67	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HICPPONB_02350	0.0	poxL	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HICPPONB_02351	3.7e-279	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
HICPPONB_02352	4.66e-267	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
HICPPONB_02353	9.5e-264	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
HICPPONB_02354	7.23e-66	-	-	-	-	-	-	-	-
HICPPONB_02355	1.11e-203	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HICPPONB_02356	6.06e-132	-	-	-	V	ko:K07448	-	ko00000,ko02048	Restriction endonuclease
HICPPONB_02357	1.85e-200	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	converts alpha-aldose to the beta-anomer
HICPPONB_02358	3.11e-271	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HICPPONB_02359	4.33e-132	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HICPPONB_02361	2.32e-104	-	-	-	K	-	-	-	Acetyltransferase GNAT Family
HICPPONB_02362	1.65e-111	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HICPPONB_02363	6.77e-167	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HICPPONB_02364	1.15e-187	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HICPPONB_02365	5.82e-197	XK27_08835	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HICPPONB_02366	2.77e-94	-	-	-	-	-	-	-	-
HICPPONB_02367	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HICPPONB_02368	1.33e-275	-	-	-	V	-	-	-	Beta-lactamase
HICPPONB_02369	2.51e-195	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HICPPONB_02370	6.4e-280	-	-	-	V	-	-	-	Beta-lactamase
HICPPONB_02371	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HICPPONB_02372	1.62e-161	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HICPPONB_02373	3.04e-279	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HICPPONB_02374	1.13e-177	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HICPPONB_02375	0.0	yuxL	3.4.19.1	-	E	ko:K01303	-	ko00000,ko01000,ko01002	Prolyl oligopeptidase family
HICPPONB_02378	9.9e-202	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HICPPONB_02379	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
HICPPONB_02380	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HICPPONB_02381	3.54e-176	ypaC	-	-	Q	-	-	-	Methyltransferase domain
HICPPONB_02382	0.0	-	-	-	S	-	-	-	ABC transporter
HICPPONB_02383	4.6e-221	draG	-	-	O	-	-	-	ADP-ribosylglycohydrolase
HICPPONB_02384	1.26e-139	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HICPPONB_02385	4.42e-54	-	-	-	-	-	-	-	-
HICPPONB_02386	1.8e-173	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
HICPPONB_02387	2.32e-188	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HICPPONB_02388	7.68e-174	glcR	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
HICPPONB_02389	3.46e-103	-	-	-	T	-	-	-	Sh3 type 3 domain protein
HICPPONB_02390	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HICPPONB_02391	8.41e-241	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HICPPONB_02392	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
HICPPONB_02393	3.73e-206	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
HICPPONB_02394	3.1e-211	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HICPPONB_02395	4.91e-172	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HICPPONB_02396	3.39e-166	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HICPPONB_02397	3.74e-75	-	-	-	-	-	-	-	-
HICPPONB_02398	6.55e-270	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
HICPPONB_02399	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HICPPONB_02400	5.16e-217	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
HICPPONB_02401	3.12e-187	gntR	-	-	K	-	-	-	rpiR family
HICPPONB_02402	8.67e-88	yodA	-	-	S	-	-	-	Tautomerase enzyme
HICPPONB_02403	1.4e-204	iolJ	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
HICPPONB_02404	7.34e-223	iolE	4.2.1.44	-	G	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HICPPONB_02405	3.37e-249	iolG2	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
HICPPONB_02406	9.62e-247	-	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
HICPPONB_02407	0.0	iolD	3.7.1.22	-	E	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HICPPONB_02408	6.58e-228	iolC	2.7.1.92	-	H	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HICPPONB_02409	1.71e-200	iolB	5.3.1.30	-	G	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HICPPONB_02410	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HICPPONB_02411	0.0	iolT	-	-	EGP	ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HICPPONB_02412	3.54e-187	iolR	-	-	K	ko:K06608,ko:K11534	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
HICPPONB_02413	2.86e-211	yvgN	-	-	C	-	-	-	Aldo keto reductase
HICPPONB_02414	2.71e-182	racD	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HICPPONB_02415	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HICPPONB_02416	1.02e-103	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HICPPONB_02417	2.75e-303	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HICPPONB_02418	2.81e-278	hpk31	-	-	T	-	-	-	Histidine kinase
HICPPONB_02419	1.68e-156	vanR	-	-	K	-	-	-	response regulator
HICPPONB_02420	1.68e-155	-	-	-	-	-	-	-	-
HICPPONB_02421	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HICPPONB_02422	7.12e-169	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
HICPPONB_02423	9.76e-237	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HICPPONB_02424	3.26e-40	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
HICPPONB_02425	1.11e-201	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HICPPONB_02426	1.49e-177	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
HICPPONB_02427	7.98e-188	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HICPPONB_02428	3.22e-167	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HICPPONB_02429	4.01e-87	-	-	-	-	-	-	-	-
HICPPONB_02430	5.48e-164	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
HICPPONB_02431	6.15e-139	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HICPPONB_02432	8.1e-153	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HICPPONB_02433	1.42e-195	-	-	-	S	-	-	-	Protein of unknown function (DUF979)
HICPPONB_02434	2.66e-147	-	-	-	S	-	-	-	Protein of unknown function (DUF969)
HICPPONB_02435	1.97e-92	asp2	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HICPPONB_02436	8.12e-90	asp23	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HICPPONB_02437	4.15e-34	-	-	-	-	-	-	-	-
HICPPONB_02438	1.16e-112	-	-	-	S	-	-	-	Protein conserved in bacteria
HICPPONB_02439	4.95e-53	-	-	-	S	-	-	-	Transglycosylase associated protein
HICPPONB_02440	2.27e-94	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
HICPPONB_02441	2.86e-219	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HICPPONB_02442	2.82e-36	-	-	-	-	-	-	-	-
HICPPONB_02443	5.54e-50	-	-	-	-	-	-	-	-
HICPPONB_02444	1.34e-108	-	-	-	C	-	-	-	Flavodoxin
HICPPONB_02445	4.85e-65	-	-	-	-	-	-	-	-
HICPPONB_02446	1.47e-116	-	-	-	-	-	-	-	-
HICPPONB_02447	1.47e-07	-	-	-	-	-	-	-	-
HICPPONB_02448	6.45e-74	ywjH	-	-	S	-	-	-	Protein of unknown function (DUF1634)
HICPPONB_02449	8.76e-178	yunE	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
HICPPONB_02450	6.38e-282	-	-	-	S	ko:K06872	-	ko00000	TPM domain
HICPPONB_02451	6.18e-150	-	-	-	-	-	-	-	-
HICPPONB_02452	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
HICPPONB_02453	0.0	fnq20	-	-	S	-	-	-	FAD-NAD(P)-binding
HICPPONB_02454	2.53e-141	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
HICPPONB_02455	1.12e-283	-	-	-	V	-	-	-	ABC transporter transmembrane region
HICPPONB_02457	1.05e-275	-	-	-	S	-	-	-	nuclear-transcribed mRNA catabolic process, no-go decay
HICPPONB_02458	4.47e-98	-	-	-	S	-	-	-	NUDIX domain
HICPPONB_02460	8.18e-26	-	-	-	-	-	-	-	-
HICPPONB_02461	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HICPPONB_02462	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HICPPONB_02464	0.0	bmr3	-	-	EGP	-	-	-	Major Facilitator
HICPPONB_02465	4.77e-130	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HICPPONB_02466	0.0	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
HICPPONB_02467	4.22e-60	-	-	-	S	-	-	-	Thiamine-binding protein
HICPPONB_02468	6.39e-177	-	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
HICPPONB_02469	2.25e-202	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HICPPONB_02470	1.93e-303	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HICPPONB_02471	3.83e-197	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
HICPPONB_02472	0.0	-	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
HICPPONB_02473	2.37e-151	-	-	-	K	-	-	-	DeoR C terminal sensor domain
HICPPONB_02474	1.77e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HICPPONB_02475	0.0	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HICPPONB_02476	9.02e-76	-	-	-	-	-	-	-	-
HICPPONB_02477	4.45e-227	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
HICPPONB_02478	0.0	-	-	-	L	-	-	-	Mga helix-turn-helix domain
HICPPONB_02480	9.46e-240	ynjC	-	-	S	-	-	-	Cell surface protein
HICPPONB_02481	2.04e-171	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HICPPONB_02482	4.92e-168	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HICPPONB_02484	0.0	-	-	-	-	-	-	-	-
HICPPONB_02485	5.79e-132	yoaA	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HICPPONB_02486	6.64e-39	-	-	-	-	-	-	-	-
HICPPONB_02487	2.38e-227	mhqA	-	-	E	ko:K15975	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HICPPONB_02489	7.44e-124	-	-	-	K	-	-	-	LysR substrate binding domain
HICPPONB_02490	2.18e-278	-	-	-	S	ko:K07112	-	ko00000	Sulphur transport
HICPPONB_02491	0.0	-	-	-	P	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HICPPONB_02492	2.5e-130	-	-	-	P	ko:K02050,ko:K15552	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HICPPONB_02493	2.87e-150	-	-	-	P	ko:K15551	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	NMT1-like family
HICPPONB_02494	4.2e-130	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HICPPONB_02496	6.95e-61	-	-	-	S	ko:K09004	-	ko00000	DsrE/DsrF-like family
HICPPONB_02497	0.0	XK27_07275	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HICPPONB_02498	4.88e-72	-	-	-	S	-	-	-	Protein of unknown function (DUF1516)
HICPPONB_02499	3.64e-69	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
HICPPONB_02500	1.12e-204	-	1.6.5.5	-	C	ko:K00344	-	ko00000,ko01000	alcohol dehydrogenase
HICPPONB_02501	5.52e-112	-	-	-	K	-	-	-	Transcriptional regulator
HICPPONB_02502	2.86e-58	-	-	-	-	-	-	-	-
HICPPONB_02503	6.75e-245	ldhD3	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HICPPONB_02504	1.67e-115	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
HICPPONB_02505	2.61e-261	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HICPPONB_02506	2.67e-56	-	-	-	-	-	-	-	-
HICPPONB_02507	8.81e-265	mccF	-	-	V	-	-	-	LD-carboxypeptidase
HICPPONB_02508	4.51e-235	yveB	-	-	I	-	-	-	PAP2 superfamily
HICPPONB_02509	2.66e-57	-	-	-	S	-	-	-	Protein of unknown function (DUF2089)
HICPPONB_02510	6.4e-51	-	-	-	-	-	-	-	-
HICPPONB_02512	0.0	yvdP	-	-	C	-	-	-	COG0277 FAD FMN-containing dehydrogenases
HICPPONB_02513	7.45e-182	-	-	-	T	-	-	-	Calcineurin-like phosphoesterase superfamily domain
HICPPONB_02514	0.0	-	-	-	-	-	-	-	-
HICPPONB_02515	7.12e-127	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
HICPPONB_02516	2.5e-164	-	-	-	-	-	-	-	-
HICPPONB_02517	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
HICPPONB_02518	3.78e-170	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HICPPONB_02519	9.2e-215	yxlF	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HICPPONB_02520	1.91e-46	-	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
HICPPONB_02521	1.38e-255	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HICPPONB_02522	3.87e-42	-	-	-	-	-	-	-	-
HICPPONB_02524	1.49e-199	lysR5	-	-	K	-	-	-	LysR substrate binding domain
HICPPONB_02525	0.0	-	3.6.3.6	-	P	ko:K01535	ko00190,map00190	ko00000,ko00001,ko01000	Cation transporter/ATPase, N-terminus
HICPPONB_02526	4.34e-75	cadC5	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
HICPPONB_02527	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
HICPPONB_02528	9.64e-317	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HICPPONB_02529	5.77e-214	-	4.1.1.52	-	S	ko:K22213	-	ko00000,ko01000	Amidohydrolase
HICPPONB_02530	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HICPPONB_02531	1.02e-144	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HICPPONB_02532	3.35e-120	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
HICPPONB_02533	1.65e-152	yleF	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HICPPONB_02534	2.36e-164	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HICPPONB_02535	0.0	pts32BC	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HICPPONB_02536	4.65e-277	-	-	-	-	-	-	-	-
HICPPONB_02537	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HICPPONB_02538	1.35e-97	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HICPPONB_02539	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HICPPONB_02541	3.35e-125	-	-	-	S	-	-	-	Phospholipase A2
HICPPONB_02542	4.06e-235	-	-	-	V	-	-	-	ABC transporter transmembrane region
HICPPONB_02543	3.79e-192	-	-	-	EG	-	-	-	EamA-like transporter family
HICPPONB_02544	5.09e-93	-	-	-	L	-	-	-	NUDIX domain
HICPPONB_02545	2.33e-81	-	-	-	-	-	-	-	-
HICPPONB_02546	5.59e-249	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HICPPONB_02547	5.96e-240	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HICPPONB_02548	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HICPPONB_02549	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HICPPONB_02550	1.79e-115	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HICPPONB_02551	6.14e-280	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HICPPONB_02552	2.35e-213	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HICPPONB_02553	2.21e-179	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HICPPONB_02554	2.28e-148	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
HICPPONB_02555	2.84e-62	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HICPPONB_02556	1.36e-212	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HICPPONB_02557	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HICPPONB_02558	3.96e-182	-	-	-	-	-	-	-	-
HICPPONB_02559	3.11e-274	-	-	-	S	-	-	-	Membrane
HICPPONB_02560	3.22e-82	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HICPPONB_02561	6.43e-66	-	-	-	-	-	-	-	-
HICPPONB_02562	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HICPPONB_02563	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HICPPONB_02564	2.5e-233	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
HICPPONB_02565	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
HICPPONB_02567	7.85e-302	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
HICPPONB_02568	7.59e-245	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HICPPONB_02569	6.98e-53	-	-	-	-	-	-	-	-
HICPPONB_02570	1.22e-112	-	-	-	-	-	-	-	-
HICPPONB_02571	6.71e-34	-	-	-	-	-	-	-	-
HICPPONB_02572	1.72e-213	-	-	-	EG	-	-	-	EamA-like transporter family
HICPPONB_02573	1.64e-142	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HICPPONB_02574	9.59e-101	usp5	-	-	T	-	-	-	universal stress protein
HICPPONB_02575	3.25e-74	-	-	-	K	-	-	-	Helix-turn-helix domain
HICPPONB_02576	6.37e-187	ptp3	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HICPPONB_02577	3.18e-285	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Domain of unknown function (DUF1730)
HICPPONB_02578	1.54e-84	-	-	-	-	-	-	-	-
HICPPONB_02579	7.09e-113	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HICPPONB_02580	5.77e-93	adhR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HICPPONB_02581	4.3e-106	-	-	-	C	-	-	-	Flavodoxin
HICPPONB_02582	1.81e-251	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HICPPONB_02583	6.48e-147	-	-	-	GM	-	-	-	NmrA-like family
HICPPONB_02584	1.68e-31	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HICPPONB_02586	2.29e-131	-	-	-	Q	-	-	-	methyltransferase
HICPPONB_02587	8.5e-134	-	-	-	T	-	-	-	Sh3 type 3 domain protein
HICPPONB_02588	3.89e-151	-	-	-	F	-	-	-	glutamine amidotransferase
HICPPONB_02589	5.22e-174	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2263)
HICPPONB_02590	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
HICPPONB_02591	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HICPPONB_02592	8.38e-80	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HICPPONB_02593	4.8e-128	maf	-	-	D	ko:K06287	-	ko00000	nucleoside-triphosphate diphosphatase activity
HICPPONB_02594	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HICPPONB_02595	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HICPPONB_02596	0.0	ydaO	-	-	E	-	-	-	amino acid
HICPPONB_02597	6.55e-75	-	-	-	S	-	-	-	Domain of unknown function (DUF1827)
HICPPONB_02598	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HICPPONB_02599	1.7e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HICPPONB_02600	6.1e-143	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HICPPONB_02601	1.18e-250	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HICPPONB_02602	9.44e-236	-	-	-	-	-	-	-	-
HICPPONB_02603	1.39e-202	-	-	-	V	ko:K01990,ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HICPPONB_02604	4.97e-81	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HICPPONB_02605	1.1e-151	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HICPPONB_02606	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
HICPPONB_02607	3.12e-68	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HICPPONB_02608	9.93e-242	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HICPPONB_02609	8.44e-130	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
HICPPONB_02610	3.82e-168	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
HICPPONB_02611	1.7e-95	-	-	-	-	-	-	-	-
HICPPONB_02612	2.42e-117	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
HICPPONB_02613	6.13e-232	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
HICPPONB_02614	3.86e-185	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HICPPONB_02615	2.43e-182	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HICPPONB_02616	7.92e-76	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HICPPONB_02617	2.66e-222	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HICPPONB_02618	1.14e-69	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
HICPPONB_02619	5.92e-150	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HICPPONB_02620	1.71e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HICPPONB_02621	1.26e-139	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HICPPONB_02622	7e-49	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HICPPONB_02623	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HICPPONB_02624	1.79e-117	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HICPPONB_02625	9.05e-67	-	-	-	-	-	-	-	-
HICPPONB_02626	1.41e-140	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
HICPPONB_02627	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HICPPONB_02628	1.15e-59	-	-	-	-	-	-	-	-
HICPPONB_02629	1.49e-225	ccpB	-	-	K	-	-	-	lacI family
HICPPONB_02630	0.0	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HICPPONB_02631	1.98e-204	-	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HICPPONB_02632	1.37e-74	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HICPPONB_02633	7.23e-108	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HICPPONB_02634	1.92e-283	mdtG	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HICPPONB_02635	9.19e-195	-	-	-	K	-	-	-	acetyltransferase
HICPPONB_02636	5.94e-87	-	-	-	-	-	-	-	-
HICPPONB_02637	1.97e-276	yceI	-	-	G	ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
HICPPONB_02638	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HICPPONB_02639	1.89e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HICPPONB_02640	6.87e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HICPPONB_02641	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
HICPPONB_02642	0.0	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
HICPPONB_02643	1.04e-87	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
HICPPONB_02644	1.7e-117	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Cobalamin adenosyltransferase
HICPPONB_02645	1.36e-125	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
HICPPONB_02646	7.16e-82	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
HICPPONB_02647	0.0	rtpR	1.17.4.2	-	F	ko:K00527	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	ribonucleoside-triphosphate reductase activity
HICPPONB_02648	3.77e-102	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
HICPPONB_02649	9.91e-205	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HICPPONB_02650	2.29e-130	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HICPPONB_02651	2.09e-30	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HICPPONB_02652	4.58e-220	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HICPPONB_02653	2.44e-216	menA	2.5.1.74	-	M	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
HICPPONB_02654	2.2e-252	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HICPPONB_02655	6.86e-187	cad	-	-	S	ko:K20379	ko02024,map02024	ko00000,ko00001	FMN_bind
HICPPONB_02656	0.0	ndh	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HICPPONB_02657	4.76e-105	-	-	-	S	-	-	-	NusG domain II
HICPPONB_02658	1.03e-127	hepA	2.5.1.30	-	S	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase component I
HICPPONB_02659	1.05e-228	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HICPPONB_02661	4.65e-158	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	Rossmann-like domain
HICPPONB_02662	1.73e-247	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
HICPPONB_02664	5.04e-127	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
HICPPONB_02665	2.58e-180	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HICPPONB_02666	4.83e-98	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HICPPONB_02667	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HICPPONB_02668	0.0	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
HICPPONB_02669	1.53e-138	-	-	-	-	-	-	-	-
HICPPONB_02671	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HICPPONB_02672	1.64e-237	XK27_10475	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HICPPONB_02673	2.59e-153	rpiA1	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HICPPONB_02674	7.02e-182	-	-	-	K	-	-	-	SIS domain
HICPPONB_02675	1.52e-144	yhfC	-	-	S	-	-	-	Putative membrane peptidase family (DUF2324)
HICPPONB_02676	1.13e-225	-	-	-	S	-	-	-	Membrane
HICPPONB_02677	1.52e-81	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
HICPPONB_02678	9.99e-288	inlJ	-	-	M	-	-	-	MucBP domain
HICPPONB_02679	2.26e-169	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HICPPONB_02680	5.02e-149	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HICPPONB_02681	5.08e-156	-	-	-	K	-	-	-	sequence-specific DNA binding
HICPPONB_02682	1.11e-260	yacL	-	-	S	-	-	-	domain protein
HICPPONB_02683	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HICPPONB_02684	4.85e-130	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTPase
HICPPONB_02685	1e-66	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
HICPPONB_02686	5.93e-93	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
HICPPONB_02687	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
HICPPONB_02688	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HICPPONB_02689	6.6e-255	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HICPPONB_02690	2.59e-277	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HICPPONB_02691	1.17e-213	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HICPPONB_02692	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HICPPONB_02693	0.0	ppdK	2.7.9.1	-	G	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the PEP-utilizing enzyme family
HICPPONB_02694	3.65e-208	-	-	-	S	-	-	-	zinc-ribbon domain
HICPPONB_02695	4.74e-30	-	-	-	-	-	-	-	-
HICPPONB_02696	1.91e-167	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HICPPONB_02697	6.6e-106	-	-	-	F	-	-	-	NUDIX domain
HICPPONB_02698	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HICPPONB_02699	6e-136	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HICPPONB_02700	1.83e-256	-	-	-	-	-	-	-	-
HICPPONB_02701	2.4e-214	-	-	-	S	-	-	-	Putative esterase
HICPPONB_02702	2.67e-13	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
HICPPONB_02703	2.84e-88	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	MarR family
HICPPONB_02704	1.64e-62	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2316)
HICPPONB_02705	3.76e-288	-	-	-	C	-	-	-	Iron-containing alcohol dehydrogenase
HICPPONB_02706	1.47e-245	-	-	-	E	-	-	-	Alpha/beta hydrolase family
HICPPONB_02707	6.79e-95	-	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
HICPPONB_02708	2.44e-99	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HICPPONB_02709	3.96e-226	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HICPPONB_02710	1.38e-45	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HICPPONB_02711	4.56e-220	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
HICPPONB_02712	2.07e-210	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
HICPPONB_02713	8.26e-164	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HICPPONB_02714	6.98e-284	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HICPPONB_02715	8.8e-93	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HICPPONB_02716	3.23e-98	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HICPPONB_02717	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
HICPPONB_02718	8.74e-194	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HICPPONB_02719	3.41e-184	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
HICPPONB_02720	3.95e-297	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HICPPONB_02721	7e-210	-	-	-	GM	-	-	-	NmrA-like family
HICPPONB_02722	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HICPPONB_02723	1.01e-230	purR2	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
HICPPONB_02724	0.0	malL	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HICPPONB_02725	0.0	pts26BCA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HICPPONB_02726	7.06e-271	-	-	-	-	-	-	-	-
HICPPONB_02727	6.38e-98	-	-	-	-	-	-	-	-
HICPPONB_02728	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HICPPONB_02729	5.52e-252	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HICPPONB_02730	1.96e-189	hsdS	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain
HICPPONB_02731	3.37e-221	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HICPPONB_02732	3.59e-91	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
HICPPONB_02733	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF1524)
HICPPONB_02734	6.74e-176	-	-	-	-	-	-	-	-
HICPPONB_02735	1.88e-131	hyuA	-	-	EQ	-	-	-	Hydantoinase/oxoprolinase N-terminal region
HICPPONB_02736	6.84e-186	frlD1	2.7.1.218	-	G	ko:K10710	-	ko00000,ko01000	pfkB family carbohydrate kinase
HICPPONB_02737	7.56e-76	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HICPPONB_02738	4.36e-103	-	-	-	-	-	-	-	-
HICPPONB_02739	0.0	-	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Helix-hairpin-helix containing domain
HICPPONB_02740	1.76e-177	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2087)
HICPPONB_02741	3.02e-173	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
HICPPONB_02742	0.0	galA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HICPPONB_02743	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HICPPONB_02745	4.46e-88	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HICPPONB_02746	1.79e-268	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HICPPONB_02747	1.09e-68	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system cellobiose-specific component IIA
HICPPONB_02748	2.39e-109	-	-	-	-	-	-	-	-
HICPPONB_02749	1.7e-190	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
HICPPONB_02750	0.0	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
HICPPONB_02751	1.34e-170	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
HICPPONB_02752	4.1e-130	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HICPPONB_02753	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HICPPONB_02754	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HICPPONB_02755	1.4e-208	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HICPPONB_02756	3.01e-227	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HICPPONB_02757	4.99e-251	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HICPPONB_02758	2.59e-229	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HICPPONB_02759	6.17e-151	gpm5	-	-	G	-	-	-	Phosphoglycerate mutase family
HICPPONB_02760	6.56e-64	-	-	-	K	-	-	-	sequence-specific DNA binding
HICPPONB_02761	2.1e-49	XK27_01315	-	-	S	-	-	-	Protein of unknown function (DUF2829)
HICPPONB_02762	4.25e-159	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HICPPONB_02763	4.2e-106	ccl	-	-	S	-	-	-	QueT transporter
HICPPONB_02764	6.11e-169	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HICPPONB_02765	1.11e-169	epsB	-	-	M	-	-	-	biosynthesis protein
HICPPONB_02766	1.6e-138	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HICPPONB_02767	2.64e-161	-	-	-	-	-	-	-	-
HICPPONB_02768	6.55e-236	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HICPPONB_02769	1.79e-251	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HICPPONB_02770	6.06e-132	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HICPPONB_02771	1.08e-170	-	-	-	M	-	-	-	Glycosyl transferases group 1
HICPPONB_02772	8.87e-121	-	-	GT2	M	ko:K12997	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 2
HICPPONB_02773	1.19e-130	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HICPPONB_02774	3.81e-173	-	-	-	M	-	-	-	PFAM Glycosyl transferases group 1
HICPPONB_02775	2.76e-45	-	-	-	S	-	-	-	Acyltransferase family
HICPPONB_02776	2.26e-90	rfbP	-	-	M	-	-	-	Bacterial sugar transferase
HICPPONB_02777	7.25e-207	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HICPPONB_02778	1.55e-140	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HICPPONB_02779	5.65e-257	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HICPPONB_02780	6.46e-205	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HICPPONB_02781	2.46e-195	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HICPPONB_02782	1.15e-185	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
HICPPONB_02783	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
HICPPONB_02784	1.94e-86	spx2	-	-	P	ko:K16509	-	ko00000	ArsC family
HICPPONB_02785	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	phosphatase activity
HICPPONB_02786	1.29e-186	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HICPPONB_02787	1.67e-133	-	-	-	M	-	-	-	Peptidase_C39 like family
HICPPONB_02788	1.45e-61	-	-	-	M	-	-	-	Peptidase_C39 like family
HICPPONB_02789	2.59e-131	-	-	-	M	-	-	-	Sortase family
HICPPONB_02790	8.73e-262	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HICPPONB_02791	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HICPPONB_02792	1.18e-255	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HICPPONB_02793	6.91e-280	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
HICPPONB_02794	0.0	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
HICPPONB_02795	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HICPPONB_02796	0.0	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HICPPONB_02797	4.96e-219	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HICPPONB_02798	5.83e-73	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HICPPONB_02799	1.32e-221	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HICPPONB_02800	1.55e-312	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HICPPONB_02801	7.64e-189	spl	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
HICPPONB_02802	9.94e-90	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HICPPONB_02803	2.09e-143	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
HICPPONB_02804	9.35e-15	-	-	-	-	-	-	-	-
HICPPONB_02805	3.91e-109	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HICPPONB_02807	1.6e-224	-	-	-	-	-	-	-	-
HICPPONB_02808	6.35e-174	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HICPPONB_02809	2.05e-189	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HICPPONB_02810	1.44e-141	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HICPPONB_02811	3.76e-140	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HICPPONB_02812	7.67e-224	cps2D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
HICPPONB_02813	7.89e-139	tuaG	-	GT2	M	ko:K16698	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
HICPPONB_02814	5.34e-162	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
HICPPONB_02815	3.55e-312	cps2E	-	-	M	-	-	-	Bacterial sugar transferase
HICPPONB_02816	3.24e-126	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HICPPONB_02817	6.13e-104	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
HICPPONB_02818	1.35e-300	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
HICPPONB_02819	4.86e-150	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
HICPPONB_02820	7.95e-317	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HICPPONB_02821	3.74e-243	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HICPPONB_02822	2.48e-292	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HICPPONB_02823	9.93e-136	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HICPPONB_02824	1.15e-169	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
HICPPONB_02825	1.22e-165	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HICPPONB_02826	9.69e-310	ymfH	-	-	S	-	-	-	Peptidase M16
HICPPONB_02827	2.21e-294	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
HICPPONB_02828	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HICPPONB_02829	4.04e-94	-	-	-	S	-	-	-	Protein of unknown function (DUF1149)
HICPPONB_02830	3.21e-125	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HICPPONB_02831	1.63e-198	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
HICPPONB_02832	1.94e-219	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HICPPONB_02833	4.94e-245	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HICPPONB_02834	4.12e-56	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HICPPONB_02835	2e-82	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HICPPONB_02836	3.81e-253	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HICPPONB_02837	2.19e-183	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HICPPONB_02838	3.18e-148	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
HICPPONB_02839	9.8e-259	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HICPPONB_02840	1.22e-219	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HICPPONB_02841	1.05e-193	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HICPPONB_02842	1.19e-158	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HICPPONB_02843	7.28e-138	-	-	-	S	-	-	-	CYTH
HICPPONB_02844	6.41e-148	yjbH	-	-	Q	-	-	-	Thioredoxin
HICPPONB_02845	6e-273	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HICPPONB_02846	3.22e-311	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HICPPONB_02847	5.05e-52	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
HICPPONB_02848	0.0	cpdA	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HICPPONB_02849	2.12e-296	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HICPPONB_02851	9.78e-112	gpo	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
HICPPONB_02852	0.0	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HICPPONB_02853	0.0	tagE2	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HICPPONB_02855	1.3e-267	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HICPPONB_02856	4.58e-59	hol	-	-	S	-	-	-	Bacteriophage holin
HICPPONB_02857	3.09e-56	-	-	-	-	-	-	-	-
HICPPONB_02858	7.43e-50	-	-	-	-	-	-	-	-
HICPPONB_02859	1.39e-92	-	-	-	-	-	-	-	-
HICPPONB_02860	0.0	-	-	-	LM	-	-	-	gp58-like protein
HICPPONB_02861	3.4e-162	-	-	-	S	-	-	-	phage tail
HICPPONB_02862	0.0	-	-	-	D	-	-	-	Phage tail tape measure protein
HICPPONB_02863	2.46e-81	-	-	-	-	-	-	-	-
HICPPONB_02864	4.14e-146	-	-	-	-	-	-	-	-
HICPPONB_02865	2.6e-88	-	-	-	-	-	-	-	-
HICPPONB_02866	2.05e-72	-	-	-	-	-	-	-	-
HICPPONB_02867	3.92e-76	-	-	-	S	-	-	-	Phage head-tail joining protein
HICPPONB_02868	1.83e-70	-	-	-	-	-	-	-	-
HICPPONB_02870	5.35e-271	-	-	-	S	-	-	-	Phage capsid family
HICPPONB_02871	2.39e-164	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
HICPPONB_02872	3.99e-297	-	-	-	S	-	-	-	Phage portal protein
HICPPONB_02873	0.0	-	-	-	S	-	-	-	overlaps another CDS with the same product name
HICPPONB_02874	1.23e-81	-	-	-	-	-	-	-	-
HICPPONB_02875	4.35e-89	-	-	-	V	-	-	-	HNH endonuclease
HICPPONB_02877	4.73e-97	-	-	-	-	-	-	-	-
HICPPONB_02879	4.8e-52	-	-	-	-	-	-	-	-
HICPPONB_02880	1.1e-95	rusA	-	-	L	-	-	-	Endodeoxyribonuclease RusA
HICPPONB_02881	7.92e-135	-	-	-	S	-	-	-	HNH endonuclease
HICPPONB_02883	8.4e-56	-	-	-	-	-	-	-	-
HICPPONB_02885	1.57e-197	pi346	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
HICPPONB_02886	2.96e-157	-	-	-	L	-	-	-	Transcriptional regulator
HICPPONB_02887	2.34e-47	-	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
HICPPONB_02888	9.16e-208	recT	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
HICPPONB_02890	4.4e-213	yqaJ	-	-	L	-	-	-	YqaJ-like viral recombinase domain
HICPPONB_02894	1.01e-163	-	-	-	K	-	-	-	Transcriptional regulator
HICPPONB_02896	0.000185	-	-	-	K	-	-	-	sequence-specific DNA binding
HICPPONB_02897	0.000391	-	-	-	E	-	-	-	Pfam:DUF955
HICPPONB_02898	5.48e-13	-	-	-	-	-	-	-	-
HICPPONB_02901	5.02e-277	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HICPPONB_02902	3.49e-88	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
HICPPONB_02903	0.0	-	-	-	V	-	-	-	N-6 DNA Methylase
HICPPONB_02904	1.59e-08	-	-	-	-	-	-	-	-
HICPPONB_02905	2.9e-274	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HICPPONB_02906	1.61e-83	hol	-	-	S	-	-	-	Bacteriophage holin
HICPPONB_02907	3.86e-70	-	-	-	-	-	-	-	-
HICPPONB_02909	1.54e-41	-	-	-	-	-	-	-	-
HICPPONB_02910	0.0	-	-	-	S	-	-	-	peptidoglycan catabolic process
HICPPONB_02911	1.54e-309	-	-	-	S	-	-	-	Phage tail protein
HICPPONB_02912	0.0	-	-	-	S	-	-	-	peptidoglycan catabolic process
HICPPONB_02913	2.72e-27	-	-	-	-	-	-	-	-
HICPPONB_02914	1.39e-93	-	-	-	S	-	-	-	Pfam:Phage_TTP_1
HICPPONB_02915	1.01e-35	-	-	-	-	-	-	-	-
HICPPONB_02916	6.88e-89	-	-	-	S	-	-	-	exonuclease activity
HICPPONB_02917	1.18e-53	-	-	-	S	-	-	-	Phage head-tail joining protein
HICPPONB_02918	3.09e-36	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HICPPONB_02919	4.84e-35	-	-	-	S	-	-	-	peptidase activity
HICPPONB_02920	3.91e-276	-	-	-	S	-	-	-	peptidase activity
HICPPONB_02921	1.06e-145	-	-	-	S	-	-	-	peptidase activity
HICPPONB_02922	3.44e-301	-	-	-	S	-	-	-	Phage portal protein
HICPPONB_02924	0.0	-	-	-	S	-	-	-	Phage Terminase
HICPPONB_02925	5.1e-102	-	-	-	S	-	-	-	Phage terminase, small subunit
HICPPONB_02926	6.26e-92	-	-	-	S	-	-	-	HNH endonuclease
HICPPONB_02928	1.37e-14	-	-	-	-	-	-	-	-
HICPPONB_02930	1.59e-61	-	-	-	-	-	-	-	-
HICPPONB_02931	8.26e-83	-	-	-	S	-	-	-	HNH endonuclease
HICPPONB_02932	2.7e-278	-	-	-	S	-	-	-	GcrA cell cycle regulator
HICPPONB_02936	8.43e-68	-	-	-	-	-	-	-	-
HICPPONB_02938	6.91e-20	-	-	-	S	-	-	-	YopX protein
HICPPONB_02943	5.64e-46	-	-	-	-	-	-	-	-
HICPPONB_02946	1.13e-114	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HICPPONB_02947	1.09e-158	-	-	-	S	-	-	-	DNA methylation
HICPPONB_02948	6.61e-73	-	-	-	S	-	-	-	Protein of unknown function (DUF1064)
HICPPONB_02949	4.5e-86	-	-	-	-	-	-	-	-
HICPPONB_02950	8.31e-168	-	-	-	S	-	-	-	calcium ion binding
HICPPONB_02951	4.45e-133	-	-	-	S	-	-	-	Protein of unknown function (DUF669)
HICPPONB_02952	6.61e-164	-	-	-	S	-	-	-	AAA domain
HICPPONB_02953	1.17e-41	-	-	-	S	-	-	-	Siphovirus Gp157
HICPPONB_02954	5.54e-10	-	-	-	S	-	-	-	Siphovirus Gp157
HICPPONB_02961	1.57e-101	-	-	-	K	-	-	-	Transcriptional regulator
HICPPONB_02963	1.08e-120	-	-	-	K	-	-	-	Helix-turn-helix
HICPPONB_02964	3.04e-93	-	-	-	-	-	-	-	-
HICPPONB_02965	1.59e-228	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HICPPONB_02967	2.55e-121	-	-	-	F	-	-	-	NUDIX domain
HICPPONB_02968	2.76e-182	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HICPPONB_02969	1.58e-45	yhcC	-	-	S	ko:K07069	-	ko00000	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
HICPPONB_02970	9.39e-167	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HICPPONB_02971	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HICPPONB_02972	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HICPPONB_02973	4.28e-154	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
HICPPONB_02974	5.08e-153	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HICPPONB_02975	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HICPPONB_02976	4.66e-105	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HICPPONB_02977	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
HICPPONB_02978	7.89e-268	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HICPPONB_02979	6.55e-90	-	-	-	-	-	-	-	-