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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
EPBDHHEO_00001	1.13e-298	gnpA	2.4.1.211	-	S	ko:K15533	-	ko00000,ko01000	Lacto-N-biose phosphorylase C-terminal domain
EPBDHHEO_00002	1.47e-244	-	-	-	M	-	-	-	Glycosyltransferase like family 2
EPBDHHEO_00003	8.42e-184	cobB2	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
EPBDHHEO_00005	2.45e-61	-	-	-	-	-	-	-	-
EPBDHHEO_00006	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
EPBDHHEO_00007	8e-163	gntR	-	-	K	-	-	-	FCD
EPBDHHEO_00008	9.15e-79	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
EPBDHHEO_00009	0.0	-	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	arabinose metabolic process
EPBDHHEO_00012	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
EPBDHHEO_00013	6.98e-242	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
EPBDHHEO_00014	6.23e-102	ulaC	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
EPBDHHEO_00015	1.49e-54	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
EPBDHHEO_00016	0.0	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
EPBDHHEO_00017	1.84e-169	-	-	-	S	ko:K07043	-	ko00000	Protein of unknown function DUF45
EPBDHHEO_00018	2.68e-110	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
EPBDHHEO_00019	2.83e-240	-	-	-	EG	-	-	-	EamA-like transporter family
EPBDHHEO_00020	1.37e-305	-	-	-	P	ko:K03699	-	ko00000,ko02042	Transporter associated domain
EPBDHHEO_00021	1.5e-114	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
EPBDHHEO_00022	7.09e-153	cah	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
EPBDHHEO_00023	1.01e-137	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	C-terminal domain of 1-Cys peroxiredoxin
EPBDHHEO_00024	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
EPBDHHEO_00025	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
EPBDHHEO_00026	2.71e-189	-	-	-	EGP	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
EPBDHHEO_00028	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EPBDHHEO_00029	0.0	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
EPBDHHEO_00030	3.78e-228	-	-	-	S	-	-	-	Amidohydrolase family
EPBDHHEO_00031	1.67e-248	-	-	-	S	-	-	-	Protein conserved in bacteria
EPBDHHEO_00032	1.2e-261	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
EPBDHHEO_00033	5.42e-67	-	-	-	S	-	-	-	Protein of unknown function (DUF3073)
EPBDHHEO_00034	4.77e-31	-	-	-	K	-	-	-	LytTr DNA-binding domain
EPBDHHEO_00035	6.06e-57	-	-	-	K	-	-	-	LytTr DNA-binding domain
EPBDHHEO_00036	2e-137	-	-	-	T	-	-	-	protein histidine kinase activity
EPBDHHEO_00037	1.14e-256	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
EPBDHHEO_00038	8.14e-39	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
EPBDHHEO_00039	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
EPBDHHEO_00040	2.03e-221	-	-	-	M	-	-	-	Glycosyl transferase family 2
EPBDHHEO_00041	0.0	-	-	-	-	-	-	-	-
EPBDHHEO_00042	2.48e-255	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
EPBDHHEO_00043	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative DNA-binding domain
EPBDHHEO_00044	0.0	rfbD	1.1.1.133, 5.1.3.13	-	M	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
EPBDHHEO_00045	5.01e-61	-	-	-	L	-	-	-	Transposase DDE domain
EPBDHHEO_00046	1.97e-38	-	-	-	L	ko:K07483	-	ko00000	Transposase
EPBDHHEO_00047	0.0	-	-	-	S	ko:K09118	-	ko00000	Uncharacterised protein family (UPF0182)
EPBDHHEO_00048	5.7e-297	-	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
EPBDHHEO_00049	2.29e-252	-	-	-	-	-	-	-	-
EPBDHHEO_00050	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
EPBDHHEO_00051	4.04e-106	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
EPBDHHEO_00052	6.35e-201	-	-	-	J	-	-	-	Methyltransferase domain
EPBDHHEO_00053	5.59e-78	yccF	-	-	S	-	-	-	Inner membrane component domain
EPBDHHEO_00054	1.92e-162	-	-	-	E	-	-	-	Psort location Cytoplasmic, score 8.87
EPBDHHEO_00055	8.54e-50	-	-	-	L	ko:K07483	-	ko00000	Psort location Cytoplasmic, score 8.87
EPBDHHEO_00056	4.32e-155	-	-	-	L	ko:K07483	-	ko00000	Integrase core domain
EPBDHHEO_00060	8.1e-11	-	-	-	-	-	-	-	-
EPBDHHEO_00061	5.77e-76	-	-	-	S	-	-	-	competence protein
EPBDHHEO_00062	9.07e-151	-	-	-	LU	ko:K04096	-	ko00000	DNA recombination-mediator protein A
EPBDHHEO_00063	1.27e-10	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
EPBDHHEO_00064	1.9e-39	-	-	-	-	-	-	-	-
EPBDHHEO_00066	4.77e-247	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
EPBDHHEO_00067	3.85e-258	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
EPBDHHEO_00068	8.95e-293	-	2.6.1.1, 2.6.1.2, 2.6.1.66, 2.6.1.83	-	E	ko:K00812,ko:K08969,ko:K10206,ko:K10907,ko:K14260,ko:K14261	ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
EPBDHHEO_00069	9.77e-123	-	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
EPBDHHEO_00070	1.64e-262	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EPBDHHEO_00071	3.03e-233	acoB	1.2.4.1, 1.2.4.4	-	C	ko:K00162,ko:K11381,ko:K21417	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit
EPBDHHEO_00072	1.1e-238	acoA	1.2.4.1	-	C	ko:K00161,ko:K21416	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
EPBDHHEO_00073	1.82e-187	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
EPBDHHEO_00074	2.43e-212	iaaA	3.4.19.5	-	E	ko:K13051	-	ko00000,ko01000,ko01002	Asparaginase
EPBDHHEO_00075	2.03e-181	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EPBDHHEO_00076	0.0	pip	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	alpha/beta hydrolase fold
EPBDHHEO_00077	0.0	-	-	-	T	-	-	-	Histidine kinase
EPBDHHEO_00078	1.69e-170	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
EPBDHHEO_00079	0.0	-	-	-	I	-	-	-	PAP2 superfamily
EPBDHHEO_00080	0.0	-	-	-	MV	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
EPBDHHEO_00081	5.11e-214	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
EPBDHHEO_00082	0.0	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Aminotransferase class-V
EPBDHHEO_00083	9.86e-202	-	-	-	S	-	-	-	Putative ABC-transporter type IV
EPBDHHEO_00084	3.62e-212	pdxY	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
EPBDHHEO_00085	0.0	sdhA	1.3.5.1, 1.3.5.4, 1.4.3.16	-	C	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	Succinate dehydrogenase flavoprotein subunit
EPBDHHEO_00086	1.82e-20	dprA	-	-	LU	ko:K04096	-	ko00000	DNA recombination-mediator protein A
EPBDHHEO_00087	3.17e-110	-	-	-	Q	-	-	-	Acetyltransferase (GNAT) domain
EPBDHHEO_00088	2.61e-198	-	-	-	I	-	-	-	Serine aminopeptidase, S33
EPBDHHEO_00089	3.02e-70	-	-	-	S	-	-	-	Putative heavy-metal-binding
EPBDHHEO_00090	9.18e-60	-	-	-	D	-	-	-	DivIVA domain protein
EPBDHHEO_00091	1.58e-117	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
EPBDHHEO_00092	0.0	-	-	-	KL	-	-	-	Domain of unknown function (DUF3427)
EPBDHHEO_00094	4.98e-252	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EPBDHHEO_00096	7.01e-149	-	-	-	-	-	-	-	-
EPBDHHEO_00097	5.37e-215	-	-	-	EG	-	-	-	EamA-like transporter family
EPBDHHEO_00098	1.83e-262	pldB	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Serine aminopeptidase, S33
EPBDHHEO_00099	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
EPBDHHEO_00100	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
EPBDHHEO_00101	0.0	pepX	3.4.14.5	-	E	ko:K01278	ko04974,map04974	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Dipeptidyl peptidase IV (DPP IV) N-terminal region
EPBDHHEO_00102	3.69e-167	fhaA	-	-	T	-	-	-	Protein of unknown function (DUF2662)
EPBDHHEO_00103	1.44e-122	fhaB	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
EPBDHHEO_00104	0.0	pstP	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Sigma factor PP2C-like phosphatases
EPBDHHEO_00105	0.0	rodA	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
EPBDHHEO_00106	0.0	pbpA	-	-	M	ko:K05364	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
EPBDHHEO_00107	5.69e-234	pknA	2.7.11.1	-	T	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
EPBDHHEO_00108	0.0	pknB	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
EPBDHHEO_00109	9.5e-156	trpG	2.6.1.85, 4.1.3.27	-	EH	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	para-aminobenzoate synthase glutamine amidotransferase component II
EPBDHHEO_00110	5.65e-296	srtB	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
EPBDHHEO_00111	1.18e-182	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
EPBDHHEO_00112	1.77e-93	crgA	-	-	D	-	-	-	Involved in cell division
EPBDHHEO_00113	0.0	-	-	-	L	-	-	-	ribosomal rna small subunit methyltransferase
EPBDHHEO_00114	4.85e-186	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
EPBDHHEO_00115	7.68e-47	-	-	-	-	-	-	-	-
EPBDHHEO_00116	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
EPBDHHEO_00117	5.53e-96	-	-	-	I	-	-	-	Sterol carrier protein
EPBDHHEO_00118	2.19e-60	-	-	-	L	ko:K07485	-	ko00000	Transposase
EPBDHHEO_00119	2.66e-68	istB	-	-	L	-	-	-	IstB-like ATP binding protein
EPBDHHEO_00120	7.04e-57	-	-	-	L	-	-	-	Integrase core domain
EPBDHHEO_00121	0.0	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
EPBDHHEO_00122	1.9e-17	-	-	-	-	-	-	-	-
EPBDHHEO_00123	1.53e-24	yccF	-	-	S	-	-	-	Inner membrane component domain
EPBDHHEO_00124	0.0	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
EPBDHHEO_00125	2.49e-28	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
EPBDHHEO_00127	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Mur ligase middle domain
EPBDHHEO_00128	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
EPBDHHEO_00129	1.46e-165	-	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
EPBDHHEO_00130	3.61e-309	-	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp
EPBDHHEO_00131	7.95e-292	-	2.6.1.33	-	M	ko:K20429	-	ko00000,ko01000	DegT/DnrJ/EryC1/StrS aminotransferase family
EPBDHHEO_00132	1.26e-244	-	-	-	V	-	-	-	Acetyltransferase (GNAT) domain
EPBDHHEO_00133	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EPBDHHEO_00134	2.64e-163	sigH	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
EPBDHHEO_00135	9.61e-84	-	-	-	-	-	-	-	-
EPBDHHEO_00136	6.49e-249	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
EPBDHHEO_00137	1.13e-231	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EPBDHHEO_00138	6.06e-119	ybaK	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EPBDHHEO_00139	3.39e-254	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
EPBDHHEO_00140	8.36e-173	-	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Thiamin pyrophosphokinase, vitamin B1 binding domain
EPBDHHEO_00141	2.74e-90	-	-	-	S	-	-	-	Spermine/spermidine synthase domain
EPBDHHEO_00142	3.07e-137	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EPBDHHEO_00143	3.31e-35	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L35
EPBDHHEO_00144	5.46e-81	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EPBDHHEO_00145	2.91e-229	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
EPBDHHEO_00146	7.59e-194	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
EPBDHHEO_00147	9.32e-191	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EPBDHHEO_00148	6.19e-113	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EPBDHHEO_00149	5.17e-192	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX hydrolase
EPBDHHEO_00150	0.0	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EPBDHHEO_00151	0.0	nadB	1.4.3.16, 2.4.2.19	-	H	ko:K00278,ko:K00767	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
EPBDHHEO_00152	3.33e-211	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Quinolinate phosphoribosyl transferase, N-terminal domain
EPBDHHEO_00153	4.85e-296	iscS1	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class-V
EPBDHHEO_00154	0.0	typA	-	-	T	ko:K06207	-	ko00000	Elongation factor G C-terminus
EPBDHHEO_00155	1.57e-110	-	-	-	-	-	-	-	-
EPBDHHEO_00156	8.67e-255	pheA	4.2.1.51, 5.4.99.5	-	E	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
EPBDHHEO_00157	7.31e-246	tyrA	1.3.1.12	-	E	ko:K00210,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydrogenase
EPBDHHEO_00158	2.67e-56	-	-	-	-	-	-	-	-
EPBDHHEO_00159	1.73e-238	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
EPBDHHEO_00160	4.8e-226	oppB1	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
EPBDHHEO_00161	8.76e-211	oppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
EPBDHHEO_00162	0.0	oppD	-	-	P	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
EPBDHHEO_00163	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
EPBDHHEO_00164	3.49e-140	-	-	-	NO	-	-	-	SAF
EPBDHHEO_00165	1.88e-51	-	-	-	S	-	-	-	Putative regulatory protein
EPBDHHEO_00166	1.4e-154	ygfA	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	5-formyltetrahydrofolate cyclo-ligase family
EPBDHHEO_00167	9.98e-121	rimJ	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
EPBDHHEO_00168	3.19e-266	-	-	-	-	-	-	-	-
EPBDHHEO_00169	3.49e-63	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EPBDHHEO_00170	4.56e-166	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
EPBDHHEO_00171	4.72e-54	yeaC	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
EPBDHHEO_00175	2.71e-35	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L33
EPBDHHEO_00176	3.03e-277	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
EPBDHHEO_00177	5.9e-80	fdxA	-	-	C	ko:K05524	-	ko00000	4Fe-4S binding domain
EPBDHHEO_00178	2.73e-283	dapC	-	-	E	-	-	-	Aminotransferase class I and II
EPBDHHEO_00179	6.06e-303	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EPBDHHEO_00181	0.0	-	-	-	M	ko:K07282	-	ko00000	Bacterial capsule synthesis protein PGA_cap
EPBDHHEO_00182	5.69e-147	yigZ	-	-	S	-	-	-	Uncharacterized protein family UPF0029
EPBDHHEO_00183	1.25e-156	-	-	-	-	-	-	-	-
EPBDHHEO_00184	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
EPBDHHEO_00185	2.64e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EPBDHHEO_00186	1.71e-99	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
EPBDHHEO_00187	0.0	glgX	3.2.1.196, 3.2.1.68	CBM48,GH13	G	ko:K01214,ko:K02438	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
EPBDHHEO_00188	1.44e-296	-	-	-	GK	-	-	-	transcriptional repressor of nag (N-acetylglucosamine) operon K02565
EPBDHHEO_00189	0.0	adhE	1.1.1.1, 1.2.1.10, 1.2.1.81	-	C	ko:K04072,ko:K15515	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
EPBDHHEO_00190	1.36e-213	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
EPBDHHEO_00191	3.49e-111	-	-	-	S	-	-	-	YwiC-like protein
EPBDHHEO_00192	1.34e-74	-	-	-	S	-	-	-	YwiC-like protein
EPBDHHEO_00193	5.42e-67	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
EPBDHHEO_00194	6.65e-153	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EPBDHHEO_00195	1.34e-154	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
EPBDHHEO_00196	2.54e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
EPBDHHEO_00197	1.15e-196	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EPBDHHEO_00198	1.4e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EPBDHHEO_00199	1.82e-73	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EPBDHHEO_00200	2.73e-161	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EPBDHHEO_00201	2.71e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EPBDHHEO_00202	6.77e-51	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
EPBDHHEO_00203	9.4e-57	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EPBDHHEO_00204	7.32e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EPBDHHEO_00205	9.32e-70	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EPBDHHEO_00206	1.6e-133	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EPBDHHEO_00207	7.06e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EPBDHHEO_00208	9.65e-91	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EPBDHHEO_00209	2.69e-122	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EPBDHHEO_00210	1.53e-76	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EPBDHHEO_00211	5.38e-147	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EPBDHHEO_00212	1.46e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30p/L7e
EPBDHHEO_00213	1.51e-94	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
EPBDHHEO_00214	0.0	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
EPBDHHEO_00215	4.79e-129	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
EPBDHHEO_00216	6.91e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EPBDHHEO_00217	1.03e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
EPBDHHEO_00218	6.96e-83	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EPBDHHEO_00219	7.34e-86	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EPBDHHEO_00220	1.4e-236	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EPBDHHEO_00221	2.18e-94	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
EPBDHHEO_00222	2.65e-94	-	-	-	-	-	-	-	-
EPBDHHEO_00223	1.63e-53	-	-	-	-	-	-	-	-
EPBDHHEO_00224	0.0	-	-	-	D	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EPBDHHEO_00225	5.34e-244	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EPBDHHEO_00226	0.0	-	3.2.1.97	GH101	G	ko:K17624	-	ko00000,ko01000	Glycosyl hydrolase 101 beta sandwich domain
EPBDHHEO_00227	1.28e-254	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
EPBDHHEO_00228	8.58e-280	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
EPBDHHEO_00229	6.55e-226	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
EPBDHHEO_00230	1.27e-221	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
EPBDHHEO_00231	2.1e-169	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
EPBDHHEO_00232	4.95e-44	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
EPBDHHEO_00234	2.38e-293	aspC	2.6.1.1	-	E	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
EPBDHHEO_00235	2.13e-256	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EPBDHHEO_00236	0.0	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EPBDHHEO_00237	3.79e-275	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
EPBDHHEO_00238	2.12e-53	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L27 protein
EPBDHHEO_00239	1.44e-62	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
EPBDHHEO_00240	0.0	rne	3.1.26.12	-	J	ko:K08300,ko:K08301	ko03018,map03018	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	Ribonuclease E/G family
EPBDHHEO_00241	4.04e-304	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
EPBDHHEO_00242	9.55e-215	-	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
EPBDHHEO_00243	0.0	-	-	-	V	-	-	-	Efflux ABC transporter, permease protein
EPBDHHEO_00244	4.55e-210	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
EPBDHHEO_00245	2.73e-76	-	-	-	-	-	-	-	-
EPBDHHEO_00246	3.3e-86	-	-	-	-	-	-	-	-
EPBDHHEO_00247	0.0	maf	-	-	DF	ko:K06287	-	ko00000	Maf-like protein
EPBDHHEO_00248	3.72e-237	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
EPBDHHEO_00249	6.26e-305	hom	1.1.1.3, 2.7.2.4	-	E	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
EPBDHHEO_00250	0.0	nagE	2.7.1.193	-	G	ko:K02802,ko:K02803,ko:K02804	ko00520,ko02060,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
EPBDHHEO_00251	5.94e-107	-	2.7.1.208	-	G	ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
EPBDHHEO_00252	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
EPBDHHEO_00253	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
EPBDHHEO_00254	2.81e-164	-	-	-	KT	ko:K02483	-	ko00000,ko02022	Transcriptional regulatory protein, C terminal
EPBDHHEO_00255	1.91e-156	orn	-	-	L	ko:K13288	ko03008,map03008	ko00000,ko00001,ko01000,ko03009,ko03019	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EPBDHHEO_00256	1.71e-206	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
EPBDHHEO_00257	0.0	-	-	-	L	-	-	-	PIF1-like helicase
EPBDHHEO_00260	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
EPBDHHEO_00261	5.42e-219	-	-	-	-	-	-	-	-
EPBDHHEO_00262	1.98e-156	ssb2	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
EPBDHHEO_00263	0.0	pepO	3.4.24.11, 3.4.24.71	-	O	ko:K01389,ko:K01415,ko:K07386	ko04614,ko04640,ko04974,ko05010,map04614,map04640,map04974,map05010	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Peptidase family M13
EPBDHHEO_00264	2.65e-194	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
EPBDHHEO_00265	6.17e-192	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
EPBDHHEO_00266	0.0	gltA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Citrate synthase, C-terminal domain
EPBDHHEO_00267	6.88e-130	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Exonuclease, DNA polymerase III, epsilon subunit family
EPBDHHEO_00268	6.04e-249	-	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo/keto reductase family
EPBDHHEO_00269	4.03e-71	-	-	-	K	-	-	-	MerR, DNA binding
EPBDHHEO_00270	0.0	-	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
EPBDHHEO_00271	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
EPBDHHEO_00272	7.2e-281	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
EPBDHHEO_00273	0.0	nox	-	-	C	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
EPBDHHEO_00274	2.4e-297	metC1	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
EPBDHHEO_00275	1.05e-309	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
EPBDHHEO_00276	7.2e-178	hflK	-	-	O	-	-	-	prohibitin homologues
EPBDHHEO_00277	0.0	aldH	1.2.1.3, 1.2.99.10	-	C	ko:K00128,ko:K22445	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldehyde dehydrogenase family
EPBDHHEO_00278	2.38e-73	-	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
EPBDHHEO_00279	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EPBDHHEO_00283	1.48e-271	fucO	1.1.1.77, 1.1.99.37, 1.2.98.1	-	C	ko:K00048,ko:K17067	ko00625,ko00630,ko00640,ko00680,ko01120,ko01200,map00625,map00630,map00640,map00680,map01120,map01200	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
EPBDHHEO_00284	5.42e-227	-	-	-	M	-	-	-	Glycosyltransferase like family 2
EPBDHHEO_00285	0.0	-	-	-	S	-	-	-	AI-2E family transporter
EPBDHHEO_00286	1.62e-294	-	-	-	M	-	-	-	Glycosyl transferase family 21
EPBDHHEO_00287	2.64e-214	natA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
EPBDHHEO_00288	0.0	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
EPBDHHEO_00289	0.0	dacB	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-Ala-D-Ala carboxypeptidase 3 (S13) family
EPBDHHEO_00290	9.99e-269	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K00760,ko:K04075	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
EPBDHHEO_00291	2.65e-127	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
EPBDHHEO_00292	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EPBDHHEO_00293	2.05e-130	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
EPBDHHEO_00294	3.21e-210	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EPBDHHEO_00295	0.0	folK	2.7.6.3, 4.1.2.25	-	H	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EPBDHHEO_00296	4.74e-107	-	-	-	S	-	-	-	Protein of unknown function (DUF3180)
EPBDHHEO_00297	1.88e-219	tesB	-	-	I	ko:K10805	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	Thioesterase-like superfamily
EPBDHHEO_00298	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	hydrolase family 20, catalytic
EPBDHHEO_00299	0.0	yjjK	-	-	S	-	-	-	ATP-binding cassette protein, ChvD family
EPBDHHEO_00301	4.07e-56	-	-	-	M	-	-	-	domain, Protein
EPBDHHEO_00302	1.76e-161	-	-	-	-	-	-	-	-
EPBDHHEO_00303	1.24e-147	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EPBDHHEO_00304	1.74e-53	-	-	-	S	-	-	-	Protein of unknown function (DUF979)
EPBDHHEO_00305	7.29e-65	-	-	-	S	-	-	-	DUF218 domain
EPBDHHEO_00307	4.04e-149	-	-	-	S	ko:K07005	-	ko00000	Pyridoxamine 5'-phosphate oxidase
EPBDHHEO_00308	2.95e-201	-	-	-	I	-	-	-	alpha/beta hydrolase fold
EPBDHHEO_00309	4.03e-75	-	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	Major facilitator Superfamily
EPBDHHEO_00310	0.0	-	-	-	S	-	-	-	ATPases associated with a variety of cellular activities
EPBDHHEO_00311	3.68e-229	glkA	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
EPBDHHEO_00313	8.66e-16	-	-	-	EGP	-	-	-	Major facilitator superfamily
EPBDHHEO_00314	1.74e-66	-	-	-	EGP	-	-	-	Major facilitator superfamily
EPBDHHEO_00315	6.76e-49	-	-	-	C	-	-	-	Aldo/keto reductase family
EPBDHHEO_00316	0.0	-	2.5.1.49	-	H	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 9.98
EPBDHHEO_00317	1.27e-271	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
EPBDHHEO_00319	3.02e-190	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
EPBDHHEO_00320	1.96e-71	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
EPBDHHEO_00321	7.86e-06	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
EPBDHHEO_00322	6.85e-214	-	-	-	C	-	-	-	Oxidoreductase, aldo keto reductase family protein
EPBDHHEO_00323	1.83e-124	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
EPBDHHEO_00324	0.0	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase family U32 C-terminal domain
EPBDHHEO_00325	1.07e-238	yfiH	-	-	Q	ko:K05810	-	ko00000,ko01000	Multi-copper polyphenol oxidoreductase laccase
EPBDHHEO_00326	5.23e-185	ispD	1.1.1.405, 2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21681	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
EPBDHHEO_00327	2.23e-164	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EPBDHHEO_00328	2.03e-116	-	-	-	D	-	-	-	nuclear chromosome segregation
EPBDHHEO_00329	0.0	pepC2	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
EPBDHHEO_00330	6.11e-233	-	-	-	L	-	-	-	Excalibur calcium-binding domain
EPBDHHEO_00331	1.38e-277	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EPBDHHEO_00332	3.52e-309	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
EPBDHHEO_00333	1.11e-134	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
EPBDHHEO_00334	3.6e-305	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EPBDHHEO_00335	6.31e-160	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EPBDHHEO_00336	8.66e-310	phoR	2.7.13.3	-	T	ko:K07636,ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
EPBDHHEO_00337	5.44e-165	regX3	-	-	KT	ko:K07776	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
EPBDHHEO_00338	1.91e-259	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import
EPBDHHEO_00339	8.51e-219	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
EPBDHHEO_00340	2.69e-233	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
EPBDHHEO_00341	1.29e-189	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EPBDHHEO_00342	8.36e-215	-	-	-	S	-	-	-	Protein conserved in bacteria
EPBDHHEO_00344	5.92e-313	-	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
EPBDHHEO_00346	0.0	-	-	-	G	-	-	-	BNR repeat-like domain
EPBDHHEO_00347	2.15e-32	-	-	-	G	-	-	-	BNR repeat-like domain
EPBDHHEO_00348	7.12e-231	xynB2	1.1.1.169	-	E	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	lipolytic protein G-D-S-L family
EPBDHHEO_00349	5.06e-115	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EPBDHHEO_00350	5.13e-61	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
EPBDHHEO_00351	1.66e-315	-	-	-	T	-	-	-	Forkhead associated domain
EPBDHHEO_00352	0.0	-	-	-	L	-	-	-	Superfamily I DNA and RNA helicases and helicase subunits
EPBDHHEO_00353	2.87e-56	-	-	-	-	-	-	-	-
EPBDHHEO_00354	2.16e-83	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
EPBDHHEO_00355	3.75e-119	-	-	-	S	-	-	-	Aminoacyl-tRNA editing domain
EPBDHHEO_00356	3.54e-181	gluA	-	-	E	ko:K10008	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding protein of ABC transporter for glutamate K02028
EPBDHHEO_00357	2.4e-195	gluB	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
EPBDHHEO_00358	1.04e-144	gluC	-	-	E	ko:K10006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
EPBDHHEO_00359	3.8e-252	gluD	-	-	E	ko:K10007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
EPBDHHEO_00360	2.9e-254	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
EPBDHHEO_00361	0.0	-	-	-	L	-	-	-	DEAD DEAH box helicase
EPBDHHEO_00362	3.99e-180	-	-	-	V	ko:K02003,ko:K09810	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
EPBDHHEO_00363	1.25e-243	-	-	-	V	-	-	-	N-Acetylmuramoyl-L-alanine amidase
EPBDHHEO_00364	0.0	argE	-	-	E	-	-	-	Peptidase dimerisation domain
EPBDHHEO_00365	2.07e-134	-	-	-	S	-	-	-	Protein of unknown function (DUF3043)
EPBDHHEO_00366	0.0	lpdA	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EPBDHHEO_00367	5.21e-183	-	-	-	S	-	-	-	Domain of unknown function (DUF4191)
EPBDHHEO_00368	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
EPBDHHEO_00369	7.06e-204	-	-	-	S	-	-	-	Protein conserved in bacteria
EPBDHHEO_00370	2.75e-268	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
EPBDHHEO_00371	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EPBDHHEO_00372	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
EPBDHHEO_00373	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EPBDHHEO_00374	5.69e-100	-	2.8.2.22	-	S	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
EPBDHHEO_00375	7.66e-179	-	-	-	P	ko:K16784	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
EPBDHHEO_00376	3.37e-270	-	-	-	E	-	-	-	Aminotransferase class I and II
EPBDHHEO_00377	5.43e-179	ppgK	2.7.1.2, 2.7.1.63	-	GK	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
EPBDHHEO_00379	3.98e-135	-	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EPBDHHEO_00380	0.0	-	-	-	GP	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
EPBDHHEO_00381	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
EPBDHHEO_00383	0.0	rarA	-	-	L	ko:K07478	-	ko00000	Recombination factor protein RarA
EPBDHHEO_00384	1.65e-159	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
EPBDHHEO_00385	8.37e-257	-	-	-	P	-	-	-	NMT1/THI5 like
EPBDHHEO_00386	4.1e-178	-	-	-	P	-	-	-	Binding-protein-dependent transport system inner membrane component
EPBDHHEO_00387	3.6e-195	-	-	-	-	-	-	-	-
EPBDHHEO_00388	1.11e-161	-	-	-	G	-	-	-	Phosphoglycerate mutase family
EPBDHHEO_00389	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
EPBDHHEO_00390	6.15e-127	-	-	-	S	-	-	-	GtrA-like protein
EPBDHHEO_00391	9.48e-83	-	-	-	S	-	-	-	Macrophage migration inhibitory factor (MIF)
EPBDHHEO_00392	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Formate-tetrahydrofolate ligase
EPBDHHEO_00393	0.0	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
EPBDHHEO_00394	3.03e-139	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
EPBDHHEO_00395	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
EPBDHHEO_00396	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
EPBDHHEO_00397	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
EPBDHHEO_00398	7.47e-123	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
EPBDHHEO_00399	1.04e-242	-	-	-	C	-	-	-	Aldo/keto reductase family
EPBDHHEO_00400	2.45e-107	-	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 30 family
EPBDHHEO_00401	1.12e-29	-	-	-	-	-	-	-	-
EPBDHHEO_00403	6e-111	-	-	-	-	-	-	-	-
EPBDHHEO_00405	3.55e-139	-	-	-	-	ko:K03646	-	ko00000,ko02000	-
EPBDHHEO_00406	7.13e-56	-	-	-	O	-	-	-	Glutaredoxin
EPBDHHEO_00407	5.12e-202	-	-	-	S	ko:K07058	-	ko00000	Virulence factor BrkB
EPBDHHEO_00408	8.29e-129	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Redoxin
EPBDHHEO_00409	7.66e-52	urtE	-	-	E	ko:K11963	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
EPBDHHEO_00410	5.48e-150	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EPBDHHEO_00411	2.21e-109	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EPBDHHEO_00412	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
EPBDHHEO_00413	4.31e-166	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
EPBDHHEO_00414	7.06e-132	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
EPBDHHEO_00415	0.0	aroP	-	-	E	ko:K03293,ko:K11732	-	ko00000,ko02000	aromatic amino acid transport protein AroP K03293
EPBDHHEO_00416	0.0	lacZ	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
EPBDHHEO_00417	1.15e-234	-	-	-	S	-	-	-	Protein of unknown function (DUF559)
EPBDHHEO_00418	1.76e-260	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EPBDHHEO_00419	6.15e-261	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EPBDHHEO_00420	0.0	-	-	-	EGP	-	-	-	Sugar (and other) transporter
EPBDHHEO_00421	0.0	scrT	-	-	G	-	-	-	Transporter major facilitator family protein
EPBDHHEO_00422	1.38e-102	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Domain of unknown function (DUF1964)
EPBDHHEO_00423	6.32e-253	-	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
EPBDHHEO_00424	3.43e-79	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EPBDHHEO_00425	8.39e-209	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EPBDHHEO_00426	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EPBDHHEO_00427	1.25e-252	fbaA	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
EPBDHHEO_00428	0.0	-	3.2.1.8, 3.5.1.104	-	G	ko:K01181,ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
EPBDHHEO_00429	1.42e-74	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
EPBDHHEO_00431	7.82e-65	-	-	-	E	-	-	-	IrrE N-terminal-like domain
EPBDHHEO_00432	4.81e-84	-	-	-	-	-	-	-	-
EPBDHHEO_00433	4.37e-80	-	-	-	-	-	-	-	-
EPBDHHEO_00435	3.76e-163	-	-	-	S	-	-	-	Domain of unknown function (DUF4417)
EPBDHHEO_00436	7.44e-57	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
EPBDHHEO_00437	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
EPBDHHEO_00439	1.26e-218	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
EPBDHHEO_00440	0.0	fprA	1.18.1.2, 1.19.1.1	-	C	ko:K00528	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase
EPBDHHEO_00441	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
EPBDHHEO_00442	0.0	degP	-	-	O	ko:K08372	ko02020,map02020	ko00000,ko00001,ko01000,ko01002	Domain present in PSD-95, Dlg, and ZO-1/2.
EPBDHHEO_00443	0.0	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
EPBDHHEO_00445	0.0	comM	-	-	O	ko:K07391	-	ko00000	Magnesium chelatase, subunit ChlI C-terminal
EPBDHHEO_00446	2.23e-93	yraN	-	-	L	ko:K07460	-	ko00000	Belongs to the UPF0102 family
EPBDHHEO_00447	2.06e-234	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
EPBDHHEO_00448	1.44e-150	safC	-	-	S	-	-	-	O-methyltransferase
EPBDHHEO_00449	4.26e-222	fmt2	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
EPBDHHEO_00450	4.02e-257	nhaA	-	-	P	ko:K03313	-	ko00000,ko02000	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EPBDHHEO_00451	3.66e-298	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I II
EPBDHHEO_00454	2.9e-310	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EPBDHHEO_00455	9.32e-164	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
EPBDHHEO_00456	4.05e-147	clpP1	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
EPBDHHEO_00457	0.0	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
EPBDHHEO_00458	9.36e-310	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
EPBDHHEO_00459	0.0	rnd	3.1.13.5	-	J	ko:K03684	-	ko00000,ko01000,ko03016	3'-5' exonuclease
EPBDHHEO_00460	2.98e-144	-	-	-	S	-	-	-	Protein of unknown function (DUF3000)
EPBDHHEO_00461	5.19e-222	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EPBDHHEO_00462	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
EPBDHHEO_00463	7.81e-52	-	-	-	-	-	-	-	-
EPBDHHEO_00464	0.0	nadE	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EPBDHHEO_00465	6.96e-286	-	-	-	S	-	-	-	Peptidase dimerisation domain
EPBDHHEO_00466	1.49e-121	-	-	-	P	-	-	-	ABC-type metal ion transport system permease component
EPBDHHEO_00467	4.57e-211	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
EPBDHHEO_00468	3.17e-223	ppiA	5.2.1.8	-	G	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	ko00000,ko00001,ko01000,ko03110,ko04147	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EPBDHHEO_00469	4.36e-46	-	-	-	-	-	-	-	-
EPBDHHEO_00470	2.85e-65	-	-	-	-	-	-	-	-
EPBDHHEO_00473	6.92e-41	-	-	-	-	-	-	-	-
EPBDHHEO_00474	6.49e-235	-	-	-	S	-	-	-	Helix-turn-helix domain
EPBDHHEO_00475	1.42e-56	-	-	-	-	-	-	-	-
EPBDHHEO_00476	6.03e-119	-	-	-	S	-	-	-	Transcription factor WhiB
EPBDHHEO_00477	4.23e-150	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	AAA domain
EPBDHHEO_00478	5.69e-40	-	-	-	-	-	-	-	-
EPBDHHEO_00479	5.1e-122	-	-	-	-	ko:K03646	-	ko00000,ko02000	-
EPBDHHEO_00480	6.82e-291	-	-	-	S	-	-	-	HipA-like C-terminal domain
EPBDHHEO_00481	9.23e-73	-	-	-	-	-	-	-	-
EPBDHHEO_00482	1.63e-80	-	-	-	-	-	-	-	-
EPBDHHEO_00483	4.31e-259	-	-	-	K	-	-	-	WYL domain
EPBDHHEO_00484	3.55e-231	-	-	-	L	-	-	-	Domain of unknown function (DUF4368)
EPBDHHEO_00485	1.38e-59	-	-	-	S	-	-	-	Transposon-encoded protein TnpV
EPBDHHEO_00487	6.89e-138	dam	2.1.1.72	-	L	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	PFAM D12 class N6 adenine-specific DNA methyltransferase
EPBDHHEO_00488	6.1e-189	-	-	-	-	-	-	-	-
EPBDHHEO_00489	9.2e-22	-	-	-	-	-	-	-	-
EPBDHHEO_00490	1.4e-184	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.87
EPBDHHEO_00491	3.4e-172	-	-	-	D	-	-	-	Psort location Cytoplasmic, score
EPBDHHEO_00492	2.62e-23	-	-	-	S	-	-	-	Transcriptional Coactivator p15 (PC4)
EPBDHHEO_00495	0.000563	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EPBDHHEO_00496	0.0	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	MCRA family
EPBDHHEO_00497	1.34e-62	-	-	-	J	ko:K07574	-	ko00000,ko03009	CRS1_YhbY
EPBDHHEO_00498	1.07e-163	-	-	-	S	-	-	-	zinc-ribbon domain
EPBDHHEO_00499	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III alpha subunit
EPBDHHEO_00500	4.54e-53	cscA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
EPBDHHEO_00501	1.2e-19	fosC	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
EPBDHHEO_00502	3.9e-244	-	-	-	S	-	-	-	Domain of unknown function (DUF1963)
EPBDHHEO_00503	1.03e-197	uppS	2.5.1.31, 2.5.1.86, 2.5.1.88	-	H	ko:K00806,ko:K14215,ko:K21273	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EPBDHHEO_00504	3.96e-180	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
EPBDHHEO_00505	0.0	-	-	-	I	-	-	-	acetylesterase activity
EPBDHHEO_00506	9.79e-299	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EPBDHHEO_00507	2.93e-280	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
EPBDHHEO_00508	2.71e-311	-	-	-	NU	-	-	-	Tfp pilus assembly protein FimV
EPBDHHEO_00510	1.25e-79	-	-	-	-	-	-	-	-
EPBDHHEO_00511	1.84e-186	-	5.4.99.28, 5.4.99.29	-	J	ko:K06177	-	ko00000,ko01000,ko03009,ko03016	RNA pseudouridylate synthase
EPBDHHEO_00512	1.38e-103	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
EPBDHHEO_00513	3.75e-278	-	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain protein
EPBDHHEO_00514	4.29e-203	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in cellular division
EPBDHHEO_00515	5.52e-304	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Cell division ATP-binding protein FtsE
EPBDHHEO_00516	3.18e-262	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EPBDHHEO_00517	4.97e-271	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
EPBDHHEO_00518	2.08e-158	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EPBDHHEO_00519	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EPBDHHEO_00520	2.65e-250	-	-	-	I	-	-	-	PAP2 superfamily
EPBDHHEO_00521	0.0	-	-	-	M	-	-	-	PA domain
EPBDHHEO_00522	6.24e-180	-	-	-	S	ko:K11068	-	ko00000,ko02042	Haemolysin-III related
EPBDHHEO_00523	2.56e-295	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
EPBDHHEO_00524	0.0	pbp5	-	-	M	-	-	-	Transglycosylase
EPBDHHEO_00525	1.24e-99	-	-	-	L	-	-	-	Helix-turn-helix domain
EPBDHHEO_00526	3.59e-148	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
EPBDHHEO_00527	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EPBDHHEO_00528	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
EPBDHHEO_00529	3.11e-19	-	2.7.11.1	-	S	ko:K12132	-	ko00000,ko01000,ko01001	PASTA domain
EPBDHHEO_00530	0.0	-	2.7.11.1	-	S	ko:K12132	-	ko00000,ko01000,ko01001	PASTA domain
EPBDHHEO_00531	1.77e-148	-	-	-	-	-	-	-	-
EPBDHHEO_00532	7.91e-271	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EPBDHHEO_00534	1.42e-126	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
EPBDHHEO_00535	2.29e-176	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
EPBDHHEO_00536	1.21e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EPBDHHEO_00537	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III subunit gamma tau
EPBDHHEO_00538	1.61e-274	-	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Diacylglycerol kinase catalytic domain protein
EPBDHHEO_00539	3.62e-73	-	-	-	S	-	-	-	TIGRFAM helicase secretion neighborhood TadE-like protein
EPBDHHEO_00540	3.96e-55	-	-	-	S	-	-	-	Protein of unknown function (DUF4244)
EPBDHHEO_00541	2.53e-206	-	-	-	I	-	-	-	Alpha/beta hydrolase family
EPBDHHEO_00543	0.0	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
EPBDHHEO_00544	2.17e-93	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
EPBDHHEO_00545	0.0	-	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2183)
EPBDHHEO_00546	0.0	ptrB	3.4.21.83	-	E	ko:K01354	ko05142,ko05143,map05142,map05143	ko00000,ko00001,ko01000,ko01002	Peptidase, S9A B C family, catalytic domain protein
EPBDHHEO_00547	3.62e-245	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
EPBDHHEO_00549	8.97e-151	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Biotin/lipoate A/B protein ligase family
EPBDHHEO_00550	4.67e-173	crp	-	-	K	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
EPBDHHEO_00551	0.0	pon1	-	-	M	-	-	-	Transglycosylase
EPBDHHEO_00552	3.53e-276	namA	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
EPBDHHEO_00553	4.9e-288	pyrD	1.3.5.2, 1.3.98.1	-	F	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
EPBDHHEO_00554	1.2e-179	-	-	-	K	-	-	-	DeoR C terminal sensor domain
EPBDHHEO_00555	0.0	galT	2.7.7.12	-	C	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	Galactose-1-phosphate uridyl transferase, N-terminal domain
EPBDHHEO_00556	2.4e-296	galK	2.7.1.6, 2.7.7.12	-	G	ko:K00849,ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GHMP kinase family. GalK subfamily
EPBDHHEO_00557	1.32e-308	-	-	-	EGP	-	-	-	Sugar (and other) transporter
EPBDHHEO_00558	3.23e-58	-	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
EPBDHHEO_00559	0.0	-	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
EPBDHHEO_00560	1.79e-138	-	-	-	-	-	-	-	-
EPBDHHEO_00562	3.71e-156	spoU	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
EPBDHHEO_00563	2.66e-09	exsH	3.2.1.178, 3.2.1.18, 3.2.1.52	GH16,GH20,GH33	G	ko:K01186,ko:K12373,ko:K20830	ko00511,ko00513,ko00520,ko00531,ko00600,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00600,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko02042,ko03110	xyloglucan:xyloglucosyl transferase activity
EPBDHHEO_00564	3.7e-60	-	3.2.1.35	-	G	ko:K01197	ko00531,ko01100,map00531,map01100	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	Putative cell wall binding repeat
EPBDHHEO_00565	2.58e-41	exsH	3.2.1.178, 3.2.1.18, 3.2.1.52	GH16,GH20,GH33	G	ko:K01186,ko:K12373,ko:K20830	ko00511,ko00513,ko00520,ko00531,ko00600,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00600,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko02042,ko03110	xyloglucan:xyloglucosyl transferase activity
EPBDHHEO_00566	3.15e-236	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	FES
EPBDHHEO_00567	2.27e-143	-	-	-	-	-	-	-	-
EPBDHHEO_00568	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EPBDHHEO_00569	1.97e-95	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
EPBDHHEO_00570	7.71e-276	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EPBDHHEO_00571	3.38e-54	-	-	-	S	-	-	-	Protein of unknown function (DUF3046)
EPBDHHEO_00572	1.03e-105	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
EPBDHHEO_00573	1.14e-124	cinA	3.5.1.42	-	S	ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
EPBDHHEO_00574	1.69e-158	pgsA	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EPBDHHEO_00575	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK SpoIIIE family protein
EPBDHHEO_00576	3.51e-174	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
EPBDHHEO_00577	1.03e-234	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EPBDHHEO_00578	0.0	miaB	2.8.4.3	-	H	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EPBDHHEO_00579	1.42e-156	ywaC	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	Region found in RelA / SpoT proteins
EPBDHHEO_00580	2.49e-215	-	-	-	EG	-	-	-	EamA-like transporter family
EPBDHHEO_00581	8.71e-176	-	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
EPBDHHEO_00582	2.53e-150	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
EPBDHHEO_00583	0.0	-	-	-	T	-	-	-	Histidine kinase
EPBDHHEO_00584	6.09e-152	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
EPBDHHEO_00585	0.0	-	-	-	S	-	-	-	Protein of unknown function DUF262
EPBDHHEO_00586	0.0	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
EPBDHHEO_00587	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
EPBDHHEO_00588	1.4e-303	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
EPBDHHEO_00589	1.61e-147	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EPBDHHEO_00590	3.8e-135	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EPBDHHEO_00592	3.07e-252	-	-	-	EGP	-	-	-	Transmembrane secretion effector
EPBDHHEO_00593	0.0	-	-	-	S	-	-	-	Esterase-like activity of phytase
EPBDHHEO_00594	5.83e-293	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EPBDHHEO_00595	2.63e-121	cysE	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EPBDHHEO_00596	0.0	aap1	-	-	E	ko:K03294	-	ko00000	aromatic amino acid transport protein AroP K03293
EPBDHHEO_00597	0.0	alr	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EPBDHHEO_00598	3.55e-313	dgt	3.1.5.1	-	F	ko:K01129	ko00230,map00230	ko00000,ko00001,ko01000	Phosphohydrolase-associated domain
EPBDHHEO_00599	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
EPBDHHEO_00600	2.73e-206	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
EPBDHHEO_00601	5.39e-292	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
EPBDHHEO_00602	3.01e-59	-	-	-	S	ko:K06990	-	ko00000,ko04812	Memo-like protein
EPBDHHEO_00604	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EPBDHHEO_00605	5.85e-228	yogA	-	-	C	-	-	-	Zinc-binding dehydrogenase
EPBDHHEO_00606	5.14e-111	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EPBDHHEO_00607	3.47e-289	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EPBDHHEO_00608	2.66e-96	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
EPBDHHEO_00609	6.3e-60	-	-	-	-	-	-	-	-
EPBDHHEO_00610	1.3e-197	-	-	-	S	-	-	-	TIGRFAM TIGR03943 family protein
EPBDHHEO_00611	4.83e-256	-	-	-	S	ko:K07089	-	ko00000	Predicted permease
EPBDHHEO_00612	1.07e-32	-	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Ribosomal L32p protein family
EPBDHHEO_00613	3.05e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L36
EPBDHHEO_00614	7.57e-57	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
EPBDHHEO_00615	4.85e-65	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EPBDHHEO_00616	6.47e-64	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
EPBDHHEO_00617	2.69e-180	-	-	-	S	-	-	-	cobalamin synthesis protein
EPBDHHEO_00618	1.64e-209	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
EPBDHHEO_00620	0.0	lysX	-	-	S	-	-	-	Uncharacterised conserved protein (DUF2156)
EPBDHHEO_00621	0.0	-	-	-	S	-	-	-	Putative esterase
EPBDHHEO_00622	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.26
EPBDHHEO_00623	5.35e-307	purD	6.3.3.1, 6.3.4.13	-	F	ko:K01945,ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
EPBDHHEO_00624	2.1e-245	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
EPBDHHEO_00626	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the transketolase family
EPBDHHEO_00627	4.82e-278	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
EPBDHHEO_00628	8.96e-273	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
EPBDHHEO_00629	8.17e-204	-	-	-	G	-	-	-	Fructosamine kinase
EPBDHHEO_00630	2.34e-215	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
EPBDHHEO_00631	2.89e-199	-	-	-	S	-	-	-	PAC2 family
EPBDHHEO_00635	0.0	-	-	-	-	-	-	-	-
EPBDHHEO_00638	0.0	-	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EPBDHHEO_00639	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EPBDHHEO_00640	0.0	-	3.2.1.52	GH20	M	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain
EPBDHHEO_00641	2.79e-176	yebC	-	-	K	-	-	-	transcriptional regulatory protein
EPBDHHEO_00642	2.64e-129	ruvC	3.1.22.4	-	L	ko:K01159	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EPBDHHEO_00643	1.83e-135	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
EPBDHHEO_00644	2.21e-255	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
EPBDHHEO_00645	3.73e-72	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit
EPBDHHEO_00646	1.12e-130	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EPBDHHEO_00647	8.17e-285	sucC	6.2.1.5	-	F	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
EPBDHHEO_00648	1.92e-211	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EPBDHHEO_00649	1.91e-314	-	-	-	-	-	-	-	-
EPBDHHEO_00650	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
EPBDHHEO_00651	5.17e-56	-	-	-	-	-	-	-	-
EPBDHHEO_00652	3.29e-165	-	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
EPBDHHEO_00653	1.9e-186	rluB	5.4.99.19, 5.4.99.22	-	J	ko:K06178,ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
EPBDHHEO_00656	3.84e-109	-	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 28 family
EPBDHHEO_00657	1.67e-295	-	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Psort location Cytoplasmic, score 8.87
EPBDHHEO_00658	7.9e-306	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
EPBDHHEO_00659	1.51e-153	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
EPBDHHEO_00660	1.04e-169	-	-	-	M	-	-	-	Mechanosensitive ion channel
EPBDHHEO_00661	0.0	clpB	-	-	O	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
EPBDHHEO_00663	5.72e-199	-	-	-	Q	-	-	-	Fumarylacetoacetate (FAA) hydrolase family
EPBDHHEO_00664	3.04e-169	-	-	-	S	-	-	-	Domain of unknown function (DUF4854)
EPBDHHEO_00665	1.13e-271	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
EPBDHHEO_00666	0.0	-	-	-	M	-	-	-	LPXTG cell wall anchor motif
EPBDHHEO_00667	0.0	-	-	-	M	-	-	-	domain protein
EPBDHHEO_00668	2.45e-70	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Acylphosphatase
EPBDHHEO_00669	2.58e-190	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EPBDHHEO_00670	5.99e-237	gluQ	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
EPBDHHEO_00671	3.2e-176	-	-	-	M	-	-	-	Protein of unknown function (DUF3152)
EPBDHHEO_00672	3.99e-176	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
EPBDHHEO_00674	5.3e-97	-	-	-	E	-	-	-	Domain of unknown function (DUF5011)
EPBDHHEO_00675	9.21e-52	-	-	-	S	-	-	-	Parallel beta-helix repeats
EPBDHHEO_00678	2.34e-92	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
EPBDHHEO_00679	1.51e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EPBDHHEO_00680	2.38e-112	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
EPBDHHEO_00681	6.47e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
EPBDHHEO_00682	1.57e-212	-	-	-	T	-	-	-	Pfam Adenylate and Guanylate cyclase catalytic domain
EPBDHHEO_00684	4.18e-25	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
EPBDHHEO_00685	4.02e-89	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
EPBDHHEO_00686	8.19e-107	-	-	-	-	-	-	-	-
EPBDHHEO_00687	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
EPBDHHEO_00688	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
EPBDHHEO_00689	1.88e-105	-	-	-	K	-	-	-	Winged helix DNA-binding domain
EPBDHHEO_00690	1.68e-91	-	-	-	E	-	-	-	IrrE N-terminal-like domain
EPBDHHEO_00692	6.46e-205	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
EPBDHHEO_00693	1.13e-307	-	-	-	S	-	-	-	Putative ABC-transporter type IV
EPBDHHEO_00694	2.24e-103	-	-	-	-	-	-	-	-
EPBDHHEO_00695	4.47e-46	-	-	-	Q	-	-	-	phosphatase activity
EPBDHHEO_00696	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Glycosyl hydrolase family 1
EPBDHHEO_00697	1.29e-66	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
EPBDHHEO_00698	5.95e-65	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
EPBDHHEO_00699	0.0	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EPBDHHEO_00700	1.32e-85	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
EPBDHHEO_00701	1.5e-167	-	-	-	K	ko:K03489,ko:K03710	-	ko00000,ko03000	UTRA
EPBDHHEO_00702	8.08e-103	-	-	-	S	-	-	-	FMN_bind
EPBDHHEO_00703	7.76e-191	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
EPBDHHEO_00704	3.5e-276	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
EPBDHHEO_00705	1.87e-288	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
EPBDHHEO_00706	1.76e-295	-	-	-	S	-	-	-	Predicted membrane protein (DUF2318)
EPBDHHEO_00707	4.8e-150	-	-	-	P	ko:K07230	-	ko00000,ko02000	Fe2+ transport protein
EPBDHHEO_00708	0.0	-	-	-	P	ko:K07243	-	ko00000,ko02000	Iron permease FTR1 family
EPBDHHEO_00709	3.52e-32	-	-	-	G	-	-	-	MFS/sugar transport protein
EPBDHHEO_00710	2.11e-250	-	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
EPBDHHEO_00711	4.92e-53	-	-	-	S	-	-	-	Fic/DOC family
EPBDHHEO_00712	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EPBDHHEO_00713	1.47e-50	hpr	-	-	G	ko:K11189	-	ko00000,ko02000	PTS HPr component phosphorylation site
EPBDHHEO_00714	2.21e-188	-	-	-	KT	-	-	-	RESPONSE REGULATOR receiver
EPBDHHEO_00715	7.92e-247	-	-	-	V	-	-	-	VanZ like family
EPBDHHEO_00716	5.99e-143	-	1.6.5.2	-	S	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
EPBDHHEO_00717	2.53e-147	-	-	-	S	-	-	-	Putative ABC-transporter type IV
EPBDHHEO_00718	5.09e-190	-	-	-	-	-	-	-	-
EPBDHHEO_00720	7.41e-189	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
EPBDHHEO_00721	6.84e-227	-	-	-	M	-	-	-	heme binding
EPBDHHEO_00722	1.31e-103	gloA	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EPBDHHEO_00723	4.29e-161	-	-	-	-	-	-	-	-
EPBDHHEO_00724	4.87e-171	-	-	-	S	-	-	-	SOS response associated peptidase (SRAP)
EPBDHHEO_00725	1.23e-99	qseC	2.7.13.3	-	T	ko:K02484,ko:K07637,ko:K07643,ko:K07645,ko:K07649,ko:K07653,ko:K18351	ko01502,ko01503,ko02020,ko02024,map01502,map01503,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	Histidine kinase
EPBDHHEO_00726	6.93e-236	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
EPBDHHEO_00728	4.85e-46	-	-	-	S	-	-	-	Carbon-nitrogen hydrolase
EPBDHHEO_00729	1.22e-129	-	-	-	F	-	-	-	Hydrolase of X-linked nucleoside diphosphate N terminal
EPBDHHEO_00730	1.9e-74	-	-	-	K	-	-	-	Transcriptional regulator
EPBDHHEO_00731	2.67e-117	-	-	-	K	-	-	-	FR47-like protein
EPBDHHEO_00732	6.21e-160	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
EPBDHHEO_00733	8.22e-85	-	-	-	K	-	-	-	Protein of unknown function, DUF488
EPBDHHEO_00734	2.09e-207	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EPBDHHEO_00735	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
EPBDHHEO_00736	2.2e-187	-	-	-	S	-	-	-	Domain of unknown function (DUF4194)
EPBDHHEO_00737	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
EPBDHHEO_00738	0.0	-	-	-	E	-	-	-	Serine carboxypeptidase
EPBDHHEO_00739	4.93e-208	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
EPBDHHEO_00740	2.45e-218	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
EPBDHHEO_00741	2.75e-216	-	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
EPBDHHEO_00742	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
EPBDHHEO_00743	5.39e-296	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
EPBDHHEO_00744	1.12e-109	tadA	3.5.4.1, 3.5.4.33	-	FJ	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
EPBDHHEO_00745	2.59e-182	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
EPBDHHEO_00746	0.0	nhaP	-	-	P	ko:K03316	-	ko00000	Sodium/hydrogen exchanger family
EPBDHHEO_00747	6.04e-144	dcd	3.5.4.13	-	F	ko:K01494	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dCTP deaminase family
EPBDHHEO_00748	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Glycosyl hydrolase family 36 N-terminal domain
EPBDHHEO_00749	0.0	pacL2	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
EPBDHHEO_00751	2.19e-223	rlmB	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EPBDHHEO_00752	0.0	-	-	-	KLT	-	-	-	Domain of unknown function (DUF4032)
EPBDHHEO_00753	1.57e-199	-	-	-	-	-	-	-	-
EPBDHHEO_00754	3.68e-230	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
EPBDHHEO_00755	7.19e-303	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
EPBDHHEO_00756	0.0	-	-	-	S	-	-	-	LPXTG-motif cell wall anchor domain protein
EPBDHHEO_00757	2.69e-133	-	-	-	L	-	-	-	Helix-turn-helix domain
EPBDHHEO_00758	2.18e-269	ugpC	-	-	E	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
EPBDHHEO_00759	7.97e-223	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
EPBDHHEO_00760	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
EPBDHHEO_00761	1.29e-201	-	-	-	O	-	-	-	Thioredoxin
EPBDHHEO_00763	5.53e-276	rpfB	-	-	S	ko:K21688	-	ko00000	G5
EPBDHHEO_00764	6.28e-218	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
EPBDHHEO_00765	8.91e-212	ispE	2.7.1.148	-	F	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EPBDHHEO_00766	6.94e-146	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
EPBDHHEO_00767	0.0	pcnA	2.7.7.19, 2.7.7.72	-	J	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	Probable RNA and SrmB- binding site of polymerase A
EPBDHHEO_00768	3.18e-160	mutT4	-	-	L	-	-	-	Belongs to the Nudix hydrolase family
EPBDHHEO_00769	0.0	-	-	-	M	-	-	-	Conserved repeat domain
EPBDHHEO_00770	0.0	mviN	-	-	KLT	ko:K03980	-	ko00000,ko01011,ko02000	MviN-like protein
EPBDHHEO_00771	3.03e-257	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
EPBDHHEO_00772	1.14e-311	parB	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
EPBDHHEO_00773	1.5e-229	parA	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
EPBDHHEO_00774	6.35e-163	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
EPBDHHEO_00775	8.38e-120	jag	-	-	S	ko:K06346	-	ko00000	Putative single-stranded nucleic acids-binding domain
EPBDHHEO_00776	6.04e-227	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Membrane protein insertase, YidC Oxa1 family
EPBDHHEO_00777	3.88e-20	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
EPBDHHEO_00778	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EPBDHHEO_00779	1.15e-259	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
EPBDHHEO_00780	3.38e-309	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EPBDHHEO_00781	1.36e-125	-	-	-	S	-	-	-	Protein of unknown function (DUF721)
EPBDHHEO_00782	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EPBDHHEO_00783	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EPBDHHEO_00784	4.11e-104	-	-	-	S	-	-	-	Transmembrane domain of unknown function (DUF3566)
EPBDHHEO_00787	4.34e-240	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
EPBDHHEO_00788	1.09e-238	-	-	-	K	-	-	-	Periplasmic binding protein domain
EPBDHHEO_00789	1.31e-290	-	-	-	I	-	-	-	Serine aminopeptidase, S33
EPBDHHEO_00790	9.05e-12	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
EPBDHHEO_00791	4.15e-06	-	-	-	M	-	-	-	PA domain
EPBDHHEO_00792	0.0	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EPBDHHEO_00793	6.72e-158	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
EPBDHHEO_00794	1.23e-221	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
EPBDHHEO_00795	1.17e-121	-	-	-	T	-	-	-	Domain of unknown function (DUF4234)
EPBDHHEO_00796	1.66e-131	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
EPBDHHEO_00797	9.14e-25	-	-	-	-	-	-	-	-
EPBDHHEO_00798	1.46e-64	tam	2.1.1.144, 2.1.1.197	-	FG	ko:K00598,ko:K02169	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	trans-aconitate 2-methyltransferase activity
EPBDHHEO_00799	1.17e-54	-	-	-	K	-	-	-	Helix-turn-helix
EPBDHHEO_00800	8.45e-286	-	2.7.11.1	-	S	ko:K07154	-	ko00000,ko01000,ko01001,ko02048	HipA N-terminal domain
EPBDHHEO_00801	5.34e-90	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Cupin domain
EPBDHHEO_00802	1.13e-226	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
EPBDHHEO_00803	8.76e-121	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
EPBDHHEO_00804	3.14e-171	-	-	-	L	ko:K07457	-	ko00000	endonuclease III
EPBDHHEO_00805	2.8e-168	-	-	-	S	-	-	-	Enoyl-(Acyl carrier protein) reductase
EPBDHHEO_00806	5.65e-311	-	-	-	V	-	-	-	MatE
EPBDHHEO_00807	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EPBDHHEO_00808	1.36e-19	-	-	-	KLT	-	-	-	Protein tyrosine kinase
EPBDHHEO_00810	3.51e-219	-	-	-	-	-	-	-	-
EPBDHHEO_00811	1.54e-248	adh	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
EPBDHHEO_00812	2.41e-23	-	-	-	K	-	-	-	MerR family regulatory protein
EPBDHHEO_00813	2.04e-159	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EPBDHHEO_00814	7.1e-230	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
EPBDHHEO_00815	3.07e-201	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
EPBDHHEO_00816	3.67e-227	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the OMP decarboxylase family. Type 2 subfamily
EPBDHHEO_00817	0.0	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
EPBDHHEO_00818	1.83e-96	pyrI	-	-	F	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002	Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
EPBDHHEO_00819	7.76e-234	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
EPBDHHEO_00820	0.0	glnE	2.7.7.42, 2.7.7.89	-	H	ko:K00982	-	ko00000,ko01000	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
EPBDHHEO_00822	8.19e-209	metF	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
EPBDHHEO_00823	3.76e-316	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
EPBDHHEO_00824	2.46e-84	-	-	-	S	-	-	-	Domain of unknown function (DUF4418)
EPBDHHEO_00825	2.66e-271	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
EPBDHHEO_00826	2.83e-174	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
EPBDHHEO_00827	1.83e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EPBDHHEO_00828	0.0	-	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 9.99
EPBDHHEO_00829	1.53e-173	-	5.4.2.12	-	G	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
EPBDHHEO_00830	4.03e-85	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF948)
EPBDHHEO_00831	7.33e-50	-	-	-	-	-	-	-	-
EPBDHHEO_00832	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EPBDHHEO_00833	6.58e-99	ruvX	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EPBDHHEO_00834	4.48e-247	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EPBDHHEO_00835	5.3e-69	-	3.4.23.43	-	S	ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type IV leader peptidase family
EPBDHHEO_00836	4.5e-280	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EPBDHHEO_00837	0.0	aroB	2.7.1.71, 4.2.3.4	-	H	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EPBDHHEO_00838	1.87e-102	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
EPBDHHEO_00839	2.14e-21	-	-	-	-	-	-	-	-
EPBDHHEO_00840	3.46e-154	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
EPBDHHEO_00841	1.76e-05	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase (surface protein transpeptidase)
EPBDHHEO_00842	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
EPBDHHEO_00843	0.0	sufB	-	-	O	ko:K09014	-	ko00000	FeS assembly protein SufB
EPBDHHEO_00844	8.37e-298	sufD	-	-	O	ko:K09015	-	ko00000	FeS assembly protein SufD
EPBDHHEO_00845	4.3e-185	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
EPBDHHEO_00846	2.55e-306	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EPBDHHEO_00847	4.14e-132	iscU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
EPBDHHEO_00848	2.56e-141	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
EPBDHHEO_00849	4.16e-297	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
EPBDHHEO_00850	2.77e-158	-	-	-	L	-	-	-	Protein of unknown function (DUF1524)
EPBDHHEO_00851	5.17e-218	-	-	-	S	-	-	-	Oxidoreductase, aldo keto reductase family protein
EPBDHHEO_00853	2.28e-258	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
EPBDHHEO_00854	1.87e-120	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
EPBDHHEO_00855	4.02e-233	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
EPBDHHEO_00858	5.49e-142	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EPBDHHEO_00859	2.37e-198	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EPBDHHEO_00860	0.0	fadD	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
EPBDHHEO_00861	1.29e-11	tnp3521a2	-	-	L	-	-	-	Integrase core domain
EPBDHHEO_00862	2.17e-267	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
EPBDHHEO_00863	6.64e-170	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EPBDHHEO_00864	2.95e-201	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
EPBDHHEO_00865	2.33e-81	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
EPBDHHEO_00866	8.39e-167	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Class II Aldolase and Adducin N-terminal domain
EPBDHHEO_00867	7.35e-219	-	5.1.3.22	-	G	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Xylose isomerase-like TIM barrel
EPBDHHEO_00868	0.0	-	2.7.1.53	-	G	ko:K00880	ko00040,ko00053,map00040,map00053	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
EPBDHHEO_00869	1.45e-283	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
EPBDHHEO_00870	8.57e-222	-	-	-	K	-	-	-	Putative sugar-binding domain
EPBDHHEO_00871	0.0	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
EPBDHHEO_00872	0.0	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
EPBDHHEO_00874	4.95e-44	tal	2.2.1.2	-	H	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EPBDHHEO_00875	3.12e-182	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
EPBDHHEO_00876	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
EPBDHHEO_00879	7.39e-309	-	-	-	V	-	-	-	MatE
EPBDHHEO_00880	2.01e-207	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
EPBDHHEO_00881	3.53e-227	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
EPBDHHEO_00882	1.2e-45	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase SecG subunit
EPBDHHEO_00883	3.84e-189	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
EPBDHHEO_00884	1.35e-283	pgk	2.7.2.3, 5.3.1.1	-	F	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglycerate kinase
EPBDHHEO_00885	3.23e-222	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
EPBDHHEO_00886	7.42e-228	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
EPBDHHEO_00887	2.13e-230	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Shikimate dehydrogenase substrate binding domain
EPBDHHEO_00888	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
EPBDHHEO_00889	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
EPBDHHEO_00890	3.92e-118	-	-	-	-	-	-	-	-
EPBDHHEO_00891	6.32e-38	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
EPBDHHEO_00892	1.44e-149	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
EPBDHHEO_00893	1.45e-313	-	2.7.13.3	-	T	ko:K18351	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
EPBDHHEO_00894	6.38e-142	-	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
EPBDHHEO_00895	0.0	ybiT	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
EPBDHHEO_00896	1.13e-36	-	-	-	L	-	-	-	DNA integration
EPBDHHEO_00897	5.32e-36	-	-	-	-	-	-	-	-
EPBDHHEO_00898	5.46e-182	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
EPBDHHEO_00899	1.34e-304	intA	-	-	L	-	-	-	Phage integrase family
EPBDHHEO_00901	0.0	relA	2.7.6.5, 3.1.7.2	-	KT	ko:K00951,ko:K01139	ko00230,map00230	ko00000,ko00001,ko01000,ko03009	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EPBDHHEO_00902	1.23e-110	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
EPBDHHEO_00903	2.45e-63	-	-	-	S	-	-	-	Domain of unknown function (DUF4193)
EPBDHHEO_00904	1.16e-241	-	-	-	S	-	-	-	Protein of unknown function (DUF3071)
EPBDHHEO_00905	4.01e-301	-	-	-	S	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
EPBDHHEO_00906	0.0	gyrA2	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
EPBDHHEO_00907	0.0	lhr	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
EPBDHHEO_00908	1.65e-34	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
EPBDHHEO_00909	9.34e-13	-	-	-	G	-	-	-	Major Facilitator Superfamily
EPBDHHEO_00910	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
EPBDHHEO_00911	0.0	gyrB2	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
EPBDHHEO_00912	4.33e-193	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
EPBDHHEO_00913	3.03e-105	-	-	-	-	-	-	-	-
EPBDHHEO_00916	1.61e-227	-	-	-	S	ko:K07088	-	ko00000	Auxin Efflux Carrier
EPBDHHEO_00917	1.14e-151	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EPBDHHEO_00918	6.69e-173	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EPBDHHEO_00919	2.46e-315	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EPBDHHEO_00921	1.26e-118	ilvN	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
EPBDHHEO_00922	0.0	ilvB	2.2.1.6	-	H	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Thiamine pyrophosphate enzyme, central domain
EPBDHHEO_00923	1.56e-179	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
EPBDHHEO_00924	2.72e-34	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
EPBDHHEO_00925	2.17e-147	-	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
EPBDHHEO_00926	3.01e-184	-	-	-	-	-	-	-	-
EPBDHHEO_00927	4.42e-116	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EPBDHHEO_00928	1.04e-76	-	-	-	S	-	-	-	Protein of unknown function (DUF3039)
EPBDHHEO_00929	0.0	yjjK	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter
EPBDHHEO_00930	8.06e-175	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Peptidase C26
EPBDHHEO_00931	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
EPBDHHEO_00932	4.14e-212	-	-	-	P	-	-	-	Cation efflux family
EPBDHHEO_00933	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EPBDHHEO_00934	5.72e-284	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
EPBDHHEO_00935	0.0	-	-	-	U	ko:K06956	-	ko00000	Sodium:dicarboxylate symporter family
EPBDHHEO_00936	0.0	-	-	-	-	-	-	-	-
EPBDHHEO_00939	2.48e-278	steT	-	-	E	ko:K03294	-	ko00000	amino acid
EPBDHHEO_00940	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	helicase superfamily c-terminal domain
EPBDHHEO_00941	7.42e-41	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
EPBDHHEO_00942	7.72e-256	-	-	-	G	-	-	-	pfkB family carbohydrate kinase
EPBDHHEO_00944	3.51e-308	-	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
EPBDHHEO_00945	4.8e-170	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
EPBDHHEO_00946	1.65e-78	-	-	-	T	-	-	-	Toxic component of a toxin-antitoxin (TA) module
EPBDHHEO_00947	1.77e-72	-	-	-	L	-	-	-	RelB antitoxin
EPBDHHEO_00948	1.77e-300	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
EPBDHHEO_00949	4.82e-166	tam	2.1.1.144	-	S	ko:K00598	-	ko00000,ko01000	Methyltransferase domain
EPBDHHEO_00954	0.0	-	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
EPBDHHEO_00955	0.0	-	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
EPBDHHEO_00956	3.49e-216	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease/Exonuclease/phosphatase family
EPBDHHEO_00957	2.19e-195	-	-	-	S	-	-	-	Protein of unknown function (DUF3710)
EPBDHHEO_00958	3.77e-172	-	-	-	S	-	-	-	Protein of unknown function (DUF3159)
EPBDHHEO_00959	1.9e-315	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EPBDHHEO_00960	2.33e-142	-	-	-	-	-	-	-	-
EPBDHHEO_00961	0.0	ctpE	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
EPBDHHEO_00962	0.0	acnA	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EPBDHHEO_00964	2.59e-212	-	-	-	S	-	-	-	Protein conserved in bacteria
EPBDHHEO_00965	0.0	ilvD	4.2.1.9	-	H	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
EPBDHHEO_00966	9.87e-70	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
EPBDHHEO_00967	1.12e-284	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EPBDHHEO_00968	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EPBDHHEO_00969	3.86e-174	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
EPBDHHEO_00972	1.26e-197	-	1.1.1.100, 1.1.1.413	-	IQ	ko:K00059,ko:K18333,ko:K22322	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
EPBDHHEO_00973	2.74e-82	-	4.2.1.68	-	M	ko:K18334	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Enolase C-terminal domain-like
EPBDHHEO_00974	3.26e-23	-	4.2.1.68	-	M	ko:K18334	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	carboxylic acid catabolic process
EPBDHHEO_00975	4.87e-236	-	-	-	K	ko:K02529	-	ko00000,ko03000	Bacterial regulatory proteins, lacI family
EPBDHHEO_00977	1.65e-153	-	-	-	S	-	-	-	CYTH
EPBDHHEO_00978	1.03e-213	ybbN	-	-	O	ko:K05838	-	ko00000,ko03110	Tetratricopeptide repeat
EPBDHHEO_00979	8.35e-232	-	-	-	-	-	-	-	-
EPBDHHEO_00980	9.86e-241	-	-	-	-	-	-	-	-
EPBDHHEO_00981	3.78e-224	-	5.2.1.8	-	M	ko:K01802	-	ko00000,ko01000	FKBP-type peptidyl-prolyl cis-trans isomerase
EPBDHHEO_00982	1.23e-159	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
EPBDHHEO_00983	1.43e-95	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EPBDHHEO_00984	9.22e-183	-	-	-	-	-	-	-	-
EPBDHHEO_00985	5.43e-166	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
EPBDHHEO_00986	1.05e-292	-	-	-	G	-	-	-	Transmembrane secretion effector
EPBDHHEO_00987	0.0	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EPBDHHEO_00988	7.16e-279	pyr	1.3.98.1	-	F	ko:K00226	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroorotate dehydrogenase
EPBDHHEO_00989	4.56e-247	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
EPBDHHEO_00991	8.51e-273	-	-	-	KL	-	-	-	Psort location Cytoplasmic, score 8.87
EPBDHHEO_00992	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EPBDHHEO_00993	8.29e-129	sixA	-	-	T	ko:K08296	-	ko00000,ko01000	Phosphoglycerate mutase family
EPBDHHEO_00994	4.04e-265	trmI	2.1.1.219, 2.1.1.220	-	J	ko:K07442	-	ko00000,ko01000,ko03016	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EPBDHHEO_00995	1.09e-225	-	-	-	I	-	-	-	alpha/beta hydrolase fold
EPBDHHEO_00996	1.17e-34	-	-	-	S	-	-	-	Rard protein
EPBDHHEO_00997	1.34e-119	-	-	-	E	-	-	-	Rard protein
EPBDHHEO_00998	1.61e-40	-	-	-	-	-	-	-	-
EPBDHHEO_00999	4.26e-272	-	-	-	L	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
EPBDHHEO_01000	1.58e-37	-	-	-	-	ko:K07485	-	ko00000	-
EPBDHHEO_01001	2.27e-204	-	-	-	L	ko:K07485	-	ko00000	Transposase
EPBDHHEO_01002	1.07e-237	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
EPBDHHEO_01003	1.33e-64	-	-	-	S	ko:K07126	-	ko00000	Sel1-like repeats.
EPBDHHEO_01004	6.29e-192	-	-	-	S	ko:K11206	-	ko00000,ko01000	Carbon-nitrogen hydrolase
EPBDHHEO_01005	4.56e-209	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
EPBDHHEO_01006	3.37e-312	glgA	2.4.1.342	GT4	G	ko:K16148	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000,ko01003	Starch synthase catalytic domain
EPBDHHEO_01007	5.23e-107	-	-	-	-	-	-	-	-
EPBDHHEO_01008	0.0	gltD	1.4.1.13, 1.4.1.14	-	C	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
EPBDHHEO_01009	2.08e-58	gltB	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase NADPH large subunit
EPBDHHEO_01010	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EPBDHHEO_01011	2.55e-122	-	-	-	T	-	-	-	Forkhead associated domain
EPBDHHEO_01012	1.47e-101	-	-	-	B	-	-	-	Belongs to the OprB family
EPBDHHEO_01013	1.65e-211	-	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Sigma factor PP2C-like phosphatases
EPBDHHEO_01014	0.0	-	-	-	E	-	-	-	Transglutaminase-like superfamily
EPBDHHEO_01015	9.12e-299	-	-	-	S	-	-	-	Protein of unknown function DUF58
EPBDHHEO_01016	0.0	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
EPBDHHEO_01017	0.0	-	-	-	S	-	-	-	Fibronectin type 3 domain
EPBDHHEO_01018	0.0	pknK	2.7.11.1	-	KLT	ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
EPBDHHEO_01019	0.0	-	-	-	L	-	-	-	PD-(D/E)XK nuclease superfamily
EPBDHHEO_01020	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	Belongs to the helicase family. UvrD subfamily
EPBDHHEO_01021	6.85e-195	-	-	-	K	-	-	-	-acetyltransferase
EPBDHHEO_01022	8.81e-317	-	-	-	G	-	-	-	Major Facilitator Superfamily
EPBDHHEO_01024	3.22e-33	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
EPBDHHEO_01025	9.02e-45	-	-	-	L	-	-	-	Transposase
EPBDHHEO_01026	8.59e-170	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
EPBDHHEO_01027	2.33e-206	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EPBDHHEO_01028	0.0	rnj	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EPBDHHEO_01029	0.0	pepN	3.4.11.2	-	E	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Peptidase family M1 domain
EPBDHHEO_01030	0.0	vpr	-	-	O	-	-	-	Subtilase family
EPBDHHEO_01031	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EPBDHHEO_01032	3.18e-160	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EPBDHHEO_01033	0.0	-	-	-	S	-	-	-	zinc finger
EPBDHHEO_01034	2.15e-124	vsr	-	-	L	ko:K07458	-	ko00000,ko01000,ko03400	May nick specific sequences that contain T G mispairs resulting from m5C-deamination
EPBDHHEO_01035	7.65e-293	aspB	2.6.1.1	-	E	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class-V
EPBDHHEO_01036	1.48e-62	ppx1	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
EPBDHHEO_01037	2.78e-170	tmp1	-	-	S	-	-	-	Domain of unknown function (DUF4391)
EPBDHHEO_01038	8.74e-193	thiF	2.7.7.73, 2.7.7.80, 2.8.1.11	-	H	ko:K03148,ko:K21147	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	ThiF family
EPBDHHEO_01039	0.0	-	-	-	OP	-	-	-	Sulfurtransferase TusA
EPBDHHEO_01040	9.54e-234	-	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
EPBDHHEO_01041	4.35e-05	malR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
EPBDHHEO_01043	3.7e-259	-	-	-	S	ko:K18353	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01504	Endonuclease/Exonuclease/phosphatase family
EPBDHHEO_01044	1.47e-56	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EPBDHHEO_01045	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EPBDHHEO_01046	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Anaerobic ribonucleoside-triphosphate reductase
EPBDHHEO_01047	5.91e-179	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EPBDHHEO_01048	0.0	hgdC	-	-	I	-	-	-	CoA enzyme activase uncharacterised domain (DUF2229)
EPBDHHEO_01049	8.8e-210	-	-	-	-	-	-	-	-
EPBDHHEO_01050	0.0	egtA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Glutamate-cysteine ligase family 2(GCS2)
EPBDHHEO_01052	1.82e-176	serB	3.1.3.3	-	E	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01009	haloacid dehalogenase-like hydrolase
EPBDHHEO_01053	0.0	arc	-	-	O	ko:K13527	ko03050,map03050	ko00000,ko00001,ko00002,ko03051	AAA ATPase forming ring-shaped complexes
EPBDHHEO_01054	0.0	dop	3.5.1.119	-	S	ko:K20814	-	ko00000,ko01000,ko03051	Pup-ligase protein
EPBDHHEO_01055	1.98e-203	-	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase family
EPBDHHEO_01056	1.05e-28	pup	-	-	S	ko:K13570	-	ko00000,ko04121	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
EPBDHHEO_01057	0.0	pafA	6.3.1.19	-	O	ko:K13571	-	ko00000,ko00002,ko01000,ko03051	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
EPBDHHEO_01058	4.7e-57	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Belongs to the bacterial histone-like protein family
EPBDHHEO_01059	0.0	-	-	-	S	-	-	-	Lysylphosphatidylglycerol synthase TM region
EPBDHHEO_01060	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase C-terminal
EPBDHHEO_01061	0.0	-	-	-	S	-	-	-	PGAP1-like protein
EPBDHHEO_01063	1.6e-117	-	-	-	-	-	-	-	-
EPBDHHEO_01064	2.85e-198	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
EPBDHHEO_01065	7.9e-247	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
EPBDHHEO_01066	4.37e-122	-	-	-	-	-	-	-	-
EPBDHHEO_01067	3.03e-230	-	-	-	S	-	-	-	Protein of unknown function DUF58
EPBDHHEO_01068	4.58e-247	moxR	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
EPBDHHEO_01069	1.26e-55	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
EPBDHHEO_01070	1.3e-129	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
EPBDHHEO_01071	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EPBDHHEO_01072	1.03e-242	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EPBDHHEO_01073	6.96e-91	megL	4.4.1.11	-	E	ko:K01761	ko00270,ko00450,map00270,map00450	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
EPBDHHEO_01074	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
EPBDHHEO_01075	2.16e-122	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
EPBDHHEO_01076	2.68e-23	xylR	-	-	K	ko:K02529	-	ko00000,ko03000	purine nucleotide biosynthetic process
EPBDHHEO_01077	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
EPBDHHEO_01078	8.32e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EPBDHHEO_01079	3.52e-152	-	-	-	-	-	-	-	-
EPBDHHEO_01080	0.0	-	3.2.1.35	-	G	ko:K01197	ko00531,ko01100,map00531,map01100	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	beta-N-acetylglucosaminidase
EPBDHHEO_01081	1.73e-31	-	3.2.1.35	-	G	ko:K01197	ko00531,ko01100,map00531,map01100	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	beta-N-acetylglucosaminidase
EPBDHHEO_01083	2.84e-205	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Biotin/lipoate A/B protein ligase family
EPBDHHEO_01084	2.28e-127	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
EPBDHHEO_01085	4.47e-70	-	-	-	-	-	-	-	-
EPBDHHEO_01086	4.21e-66	-	-	-	-	-	-	-	-
EPBDHHEO_01087	0.0	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	Type IV secretory system Conjugative DNA transfer
EPBDHHEO_01090	7.32e-124	-	-	-	K	-	-	-	Helix-turn-helix domain protein
EPBDHHEO_01092	5.1e-199	-	-	-	-	ko:K03646	-	ko00000,ko02000	-
EPBDHHEO_01094	3.13e-268	-	-	-	M	-	-	-	CHAP domain
EPBDHHEO_01095	0.0	-	-	-	U	-	-	-	type IV secretory pathway VirB4
EPBDHHEO_01096	6.15e-84	-	-	-	S	-	-	-	PrgI family protein
EPBDHHEO_01097	2.83e-179	-	-	-	-	-	-	-	-
EPBDHHEO_01098	5.33e-36	-	-	-	-	-	-	-	-
EPBDHHEO_01099	0.0	-	-	-	D	-	-	-	Cell surface antigen C-terminus
EPBDHHEO_01100	0.0	fas	-	-	I	ko:K11533	ko00061,ko01100,ko01212,ko04931,map00061,map01100,map01212,map04931	ko00000,ko00001,ko00002,ko01000,ko01004	Beta-ketoacyl synthase, C-terminal domain
EPBDHHEO_01101	0.0	pccB	-	-	I	-	-	-	Carboxyl transferase domain
EPBDHHEO_01102	0.0	accC	6.3.4.14, 6.4.1.2, 6.4.1.3	-	I	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase L chain, ATP binding domain protein
EPBDHHEO_01103	2.14e-119	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
EPBDHHEO_01104	4.55e-194	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Biotin/lipoate A/B protein ligase family
EPBDHHEO_01105	0.0	-	-	-	-	-	-	-	-
EPBDHHEO_01106	8.27e-187	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
EPBDHHEO_01107	1.83e-167	nucS	-	-	L	ko:K07503	-	ko00000,ko01000	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
EPBDHHEO_01108	0.0	-	-	-	S	-	-	-	Zincin-like metallopeptidase
EPBDHHEO_01109	2.91e-193	sdrC	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
EPBDHHEO_01110	2.24e-86	-	-	-	S	-	-	-	Protein of unknown function (DUF3052)
EPBDHHEO_01111	3.24e-247	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
EPBDHHEO_01112	2.43e-78	-	-	-	S	-	-	-	Thiamine-binding protein
EPBDHHEO_01113	7.27e-211	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
EPBDHHEO_01114	4e-290	-	-	-	O	ko:K13525	ko04141,ko05134,map04141,map05134	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	AAA domain (Cdc48 subfamily)
EPBDHHEO_01115	1.62e-110	-	-	-	-	-	-	-	-
EPBDHHEO_01116	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EPBDHHEO_01117	1.5e-203	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EPBDHHEO_01125	6.22e-285	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
EPBDHHEO_01126	8.04e-168	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
EPBDHHEO_01127	4.12e-276	-	-	-	GK	-	-	-	ROK family
EPBDHHEO_01128	5.93e-196	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
EPBDHHEO_01129	4.41e-309	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Amidohydrolase family
EPBDHHEO_01130	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
EPBDHHEO_01131	5.3e-243	dppB	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
EPBDHHEO_01132	3.07e-248	dppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
EPBDHHEO_01133	0.0	-	-	-	P	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
EPBDHHEO_01134	0.0	pepP	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Aminopeptidase P, N-terminal domain
EPBDHHEO_01135	1.25e-124	-	-	-	F	-	-	-	NUDIX domain
EPBDHHEO_01136	6.55e-66	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EPBDHHEO_01138	2.1e-105	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
EPBDHHEO_01139	1.49e-58	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
EPBDHHEO_01140	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
EPBDHHEO_01141	8.25e-53	-	-	-	S	-	-	-	Proteins of 100 residues with WXG
EPBDHHEO_01142	7.36e-227	-	-	-	-	-	-	-	-
EPBDHHEO_01143	1.23e-171	phoP	-	-	KT	ko:K02483	-	ko00000,ko02022	Response regulator receiver domain protein
EPBDHHEO_01144	0.0	phoR	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
EPBDHHEO_01145	1.23e-87	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
EPBDHHEO_01146	3.36e-248	-	-	-	S	-	-	-	Protein of unknown function (DUF3027)
EPBDHHEO_01147	2.83e-236	uspA	-	-	T	-	-	-	Belongs to the universal stress protein A family
EPBDHHEO_01148	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	ATPase family associated with various cellular activities (AAA)
EPBDHHEO_01152	2.47e-26	-	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
EPBDHHEO_01153	2.17e-243	-	-	-	K	-	-	-	Periplasmic binding protein domain
EPBDHHEO_01154	1.79e-161	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	ABC transporter permease
EPBDHHEO_01155	0.0	bga1	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
EPBDHHEO_01156	5.6e-75	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	carbohydrate transport
EPBDHHEO_01157	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
EPBDHHEO_01158	2.65e-184	coaX	2.7.1.33	-	H	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EPBDHHEO_01159	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
EPBDHHEO_01160	1.72e-218	-	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
EPBDHHEO_01161	2.91e-206	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
EPBDHHEO_01162	7.99e-183	-	-	-	EP	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	oligopeptide transport protein of the ABC superfamily, ATP-binding component
EPBDHHEO_01163	1.29e-198	-	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
EPBDHHEO_01164	5.1e-240	pdxB	-	-	EH	-	-	-	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EPBDHHEO_01165	1.45e-178	-	-	-	M	-	-	-	Parallel beta-helix repeats
EPBDHHEO_01167	4.46e-118	-	-	-	K	-	-	-	MarR family
EPBDHHEO_01168	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
EPBDHHEO_01169	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
EPBDHHEO_01170	4.37e-218	-	-	-	S	-	-	-	Patatin-like phospholipase
EPBDHHEO_01171	3.31e-197	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
EPBDHHEO_01172	6.27e-217	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
EPBDHHEO_01173	2.91e-148	-	-	-	S	-	-	-	Vitamin K epoxide reductase
EPBDHHEO_01174	3.62e-213	PPA1328	3.1.3.97, 3.1.4.57	-	S	ko:K07053,ko:K20859	ko00440,map00440	ko00000,ko00001,ko01000	DNA polymerase alpha chain like domain
EPBDHHEO_01175	9.31e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF3107)
EPBDHHEO_01176	0.0	mphA	-	-	S	-	-	-	Aminoglycoside phosphotransferase
EPBDHHEO_01179	7.47e-172	-	-	-	L	-	-	-	Phage integrase family
EPBDHHEO_01180	9.85e-140	pepE	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Peptidase family S51
EPBDHHEO_01181	0.0	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
EPBDHHEO_01182	1.39e-296	ackA	2.7.2.1	-	H	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EPBDHHEO_01183	0.0	pta	2.3.1.8	-	C	ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphate acetyltransferase
EPBDHHEO_01184	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF1846)
EPBDHHEO_01185	6.9e-158	-	-	-	-	-	-	-	-
EPBDHHEO_01187	8.37e-145	-	-	-	S	-	-	-	Protein of unknown function (DUF1294)
EPBDHHEO_01188	1.46e-37	-	-	-	-	-	-	-	-
EPBDHHEO_01189	3.68e-68	-	-	-	-	-	-	-	-
EPBDHHEO_01191	1.03e-45	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
EPBDHHEO_01193	0.0	-	-	-	M	-	-	-	Glycosyltransferase like family 2
EPBDHHEO_01194	2.15e-151	-	-	-	E	-	-	-	haloacid dehalogenase-like hydrolase
EPBDHHEO_01195	3.66e-186	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
EPBDHHEO_01196	1.24e-237	-	-	-	S	-	-	-	Conserved hypothetical protein 698
EPBDHHEO_01197	1.72e-204	-	-	-	G	-	-	-	Phosphoglycerate mutase family
EPBDHHEO_01198	1.12e-303	rutG	-	-	F	ko:K02824,ko:K03458	-	ko00000,ko02000	Permease family
EPBDHHEO_01199	6.43e-110	-	-	-	K	-	-	-	AraC-like ligand binding domain
EPBDHHEO_01201	1.03e-70	-	-	-	IQ	-	-	-	oxidoreductase activity
EPBDHHEO_01202	1.31e-175	-	-	-	V	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
EPBDHHEO_01203	8.29e-174	-	-	-	V	ko:K02068	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
EPBDHHEO_01204	3.72e-204	tsnR	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EPBDHHEO_01205	1.51e-259	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EPBDHHEO_01206	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Phenylalanyl-tRNA synthetase beta
EPBDHHEO_01207	1.23e-133	-	-	-	-	-	-	-	-
EPBDHHEO_01208	4.51e-261	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EPBDHHEO_01209	3.67e-275	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EPBDHHEO_01210	4.12e-227	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
EPBDHHEO_01211	3.97e-313	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
EPBDHHEO_01212	2.51e-234	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EPBDHHEO_01213	1.29e-112	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
EPBDHHEO_01214	5.96e-304	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
EPBDHHEO_01215	8.68e-229	-	-	-	L	-	-	-	Phage integrase family
EPBDHHEO_01216	1.94e-51	-	2.1.1.72, 3.1.21.3	-	V	ko:K01154,ko:K03427	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain
EPBDHHEO_01217	2e-41	-	-	-	-	-	-	-	-
EPBDHHEO_01218	2.59e-198	-	-	-	S	-	-	-	Domain of unknown function (DUF4357)
EPBDHHEO_01219	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	modification (methylase) protein of type I restriction-modification system K03427
EPBDHHEO_01220	3.25e-79	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain protein
EPBDHHEO_01221	0.0	-	-	-	K	-	-	-	Putative DNA-binding domain
EPBDHHEO_01222	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
EPBDHHEO_01223	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
EPBDHHEO_01224	9.62e-142	-	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
EPBDHHEO_01225	1.44e-184	-	-	-	S	-	-	-	Putative ABC-transporter type IV
EPBDHHEO_01226	2.15e-228	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EPBDHHEO_01227	2.7e-32	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EPBDHHEO_01228	3.65e-283	-	-	-	L	-	-	-	Tetratricopeptide repeat
EPBDHHEO_01229	2.53e-241	-	-	-	G	-	-	-	Haloacid dehalogenase-like hydrolase
EPBDHHEO_01231	3.26e-175	tlyA	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
EPBDHHEO_01232	1.25e-140	-	-	-	-	-	-	-	-
EPBDHHEO_01233	5.24e-150	trkA	-	-	P	ko:K03499	-	ko00000,ko02000	TrkA-N domain
EPBDHHEO_01234	0.0	trkH	-	-	P	ko:K03498	-	ko00000,ko02000	Cation transport protein
EPBDHHEO_01235	3.15e-235	nadK	2.7.1.23	-	H	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EPBDHHEO_01236	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
EPBDHHEO_01237	3.05e-159	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
EPBDHHEO_01238	6.98e-78	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
EPBDHHEO_01239	2.69e-228	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
EPBDHHEO_01240	6.23e-161	-	-	-	S	-	-	-	ABC-2 family transporter protein
EPBDHHEO_01241	3.24e-158	-	-	-	S	-	-	-	ABC-2 family transporter protein
EPBDHHEO_01242	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase N terminus
EPBDHHEO_01243	1.39e-297	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EPBDHHEO_01244	2.98e-119	-	-	-	-	-	-	-	-
EPBDHHEO_01245	3.43e-186	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EPBDHHEO_01246	6.24e-244	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EPBDHHEO_01248	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EPBDHHEO_01249	1.01e-87	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
EPBDHHEO_01250	1.65e-177	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
EPBDHHEO_01251	1.08e-101	-	-	-	S	-	-	-	Bacterial PH domain
EPBDHHEO_01252	0.0	treS_1	-	-	G	-	-	-	Alpha amylase, catalytic domain
EPBDHHEO_01254	1.92e-161	-	-	-	-	-	-	-	-
EPBDHHEO_01255	1.99e-170	-	-	-	C	-	-	-	Putative TM nitroreductase
EPBDHHEO_01256	5.96e-189	-	-	-	S	ko:K09974	-	ko00000	Domain of unknown function (DUF1287)
EPBDHHEO_01257	5.55e-91	pdxH	-	-	S	ko:K07006	-	ko00000	Pfam:Pyridox_oxidase
EPBDHHEO_01258	5.23e-72	-	-	-	-	-	-	-	-
EPBDHHEO_01259	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
EPBDHHEO_01260	1.85e-243	pitB	-	-	P	ko:K03306	-	ko00000	Phosphate transporter family
EPBDHHEO_01261	4.91e-150	-	-	-	P	ko:K07220	-	ko00000	Protein of unknown function DUF47
EPBDHHEO_01262	5.85e-158	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
EPBDHHEO_01263	1.52e-300	-	-	-	T	-	-	-	Histidine kinase
EPBDHHEO_01264	1.06e-57	pacL	3.6.3.8, 3.6.3.9	-	P	ko:K01537,ko:K01539	ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978	ko00000,ko00001,ko01000,ko04147	ATPase, P-type transporting, HAD superfamily, subfamily IC
EPBDHHEO_01265	8.3e-227	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
EPBDHHEO_01266	4.59e-289	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
EPBDHHEO_01267	0.0	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
EPBDHHEO_01268	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
EPBDHHEO_01269	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	hydrolase family 20, catalytic
EPBDHHEO_01270	9.61e-220	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
EPBDHHEO_01271	0.0	gcs2	-	-	S	ko:K06048	-	ko00000,ko01000	A circularly permuted ATPgrasp
EPBDHHEO_01272	5.51e-199	-	-	-	E	-	-	-	Transglutaminase/protease-like homologues
EPBDHHEO_01274	1.87e-111	tnp3503b	-	-	L	-	-	-	Transposase and inactivated derivatives
EPBDHHEO_01275	4.44e-225	-	-	-	-	-	-	-	-
EPBDHHEO_01276	1.16e-241	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
EPBDHHEO_01277	1.27e-226	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Cytidylyltransferase family
EPBDHHEO_01278	7.62e-120	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
EPBDHHEO_01279	6.31e-171	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
EPBDHHEO_01280	2.6e-163	-	-	-	S	-	-	-	alpha beta
EPBDHHEO_01281	4.78e-188	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EPBDHHEO_01282	3.07e-188	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
EPBDHHEO_01283	4.26e-113	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EPBDHHEO_01284	0.0	fadD3	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	long-chain-fatty acid CoA ligase
EPBDHHEO_01285	3.59e-118	-	-	-	-	-	-	-	-
EPBDHHEO_01286	1.59e-255	guaB3	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	IMP dehydrogenase family protein
EPBDHHEO_01287	1.35e-306	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the isocitrate and isopropylmalate dehydrogenases family
EPBDHHEO_01288	0.0	-	-	-	G	-	-	-	ABC transporter substrate-binding protein
EPBDHHEO_01289	1.42e-308	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EPBDHHEO_01290	1.78e-208	spoU2	-	-	J	-	-	-	SpoU rRNA Methylase family
EPBDHHEO_01292	2.18e-175	-	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
EPBDHHEO_01293	1.37e-76	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
EPBDHHEO_01294	1.49e-253	phoH	-	-	T	ko:K06217	-	ko00000	PhoH-like protein
EPBDHHEO_01295	1.82e-130	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EPBDHHEO_01296	0.0	corC	-	-	S	-	-	-	CBS domain
EPBDHHEO_01297	1.96e-236	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EPBDHHEO_01298	0.0	fadD2	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
EPBDHHEO_01299	6.9e-259	pntA	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	NAD(P) transhydrogenase subunit alpha part 1 K00324
EPBDHHEO_01300	1.08e-58	pntAB	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	4TM region of pyridine nucleotide transhydrogenase, mitoch
EPBDHHEO_01302	1.23e-210	-	-	-	EG	-	-	-	EamA-like transporter family
EPBDHHEO_01303	0.0	-	-	-	JKL	-	-	-	helicase superfamily c-terminal domain
EPBDHHEO_01304	2.4e-183	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
EPBDHHEO_01305	9.28e-218	-	5.1.3.15	-	G	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Aldose 1-epimerase
EPBDHHEO_01306	2.93e-143	-	-	-	-	-	-	-	-
EPBDHHEO_01307	0.0	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	Mycolic acid cyclopropane synthetase
EPBDHHEO_01308	9.51e-240	iolG	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
EPBDHHEO_01309	1.11e-208	-	-	-	G	ko:K05340	-	ko00000,ko02000	Sugar transport protein
EPBDHHEO_01310	7.82e-94	-	-	-	K	ko:K13633	-	ko00000,ko03000	helix_turn_helix, arabinose operon control protein
EPBDHHEO_01311	6.73e-76	-	-	-	K	ko:K13633	-	ko00000,ko03000	helix_turn_helix, arabinose operon control protein
EPBDHHEO_01313	1.85e-48	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
EPBDHHEO_01314	1.35e-89	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
EPBDHHEO_01315	4.83e-176	-	-	-	L	-	-	-	IstB-like ATP binding protein
EPBDHHEO_01316	0.0	-	-	-	L	-	-	-	Transposase
EPBDHHEO_01320	8.8e-265	-	-	-	S	ko:K06919	-	ko00000	Poxvirus D5 protein-like
EPBDHHEO_01321	6.07e-37	-	-	-	K	-	-	-	Helix-turn-helix domain
EPBDHHEO_01323	3.89e-118	-	-	-	K	-	-	-	helix-turn-helix
EPBDHHEO_01326	1.9e-109	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
EPBDHHEO_01327	6.45e-302	-	-	-	G	-	-	-	Major Facilitator Superfamily
EPBDHHEO_01329	4.85e-158	-	-	-	-	-	-	-	-
EPBDHHEO_01330	2.22e-257	idsA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
EPBDHHEO_01331	0.0	pknL	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	PASTA
EPBDHHEO_01332	3.55e-172	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
EPBDHHEO_01333	4.56e-142	-	-	-	-	-	-	-	-
EPBDHHEO_01334	1.41e-240	trpD	2.4.2.18	-	F	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EPBDHHEO_01335	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
EPBDHHEO_01336	3.68e-152	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EPBDHHEO_01338	8.06e-287	der	-	-	F	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
EPBDHHEO_01339	0.0	trpB	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
EPBDHHEO_01340	7.56e-209	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
EPBDHHEO_01341	3.87e-238	lgt	-	-	M	-	-	-	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EPBDHHEO_01342	8.92e-144	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribulose-phosphate 3-epimerase
EPBDHHEO_01343	1.2e-54	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoribosyl-ATP pyrophosphohydrolase
EPBDHHEO_01344	1.07e-200	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	ATP phosphoribosyltransferase
EPBDHHEO_01345	2.22e-151	pgsA2	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EPBDHHEO_01346	2.27e-222	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
EPBDHHEO_01347	2.78e-57	sbp	-	-	S	-	-	-	Protein of unknown function (DUF1290)
EPBDHHEO_01348	2.65e-180	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
EPBDHHEO_01349	2.88e-96	garA	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
EPBDHHEO_01350	5.64e-153	merR2	-	-	K	-	-	-	helix_turn_helix, mercury resistance
EPBDHHEO_01351	2.84e-82	-	-	-	-	-	-	-	-
EPBDHHEO_01352	2.09e-242	-	-	-	S	ko:K06889	-	ko00000	alpha beta
EPBDHHEO_01353	1.66e-128	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EPBDHHEO_01354	1.58e-287	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Amino-transferase class IV
EPBDHHEO_01355	1.65e-61	-	-	-	S	-	-	-	phosphoesterase or phosphohydrolase
EPBDHHEO_01356	2.26e-124	-	-	-	T	-	-	-	RNA ligase
EPBDHHEO_01357	1.61e-175	-	-	-	S	-	-	-	UPF0126 domain
EPBDHHEO_01358	3.91e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
EPBDHHEO_01359	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
EPBDHHEO_01360	6.95e-314	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
EPBDHHEO_01361	4.95e-18	-	-	-	S	ko:K07149	-	ko00000	Membrane
EPBDHHEO_01362	0.0	aspC	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K10907,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase, class I II
EPBDHHEO_01363	8.32e-96	dapD	2.3.1.117	-	E	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
EPBDHHEO_01364	1.25e-82	-	-	-	-	-	-	-	-
EPBDHHEO_01366	2.68e-225	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
EPBDHHEO_01367	4.6e-148	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EPBDHHEO_01368	1.65e-191	-	-	-	V	-	-	-	DivIVA protein
EPBDHHEO_01369	7.81e-56	-	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
EPBDHHEO_01370	9.4e-105	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
EPBDHHEO_01371	8.03e-295	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EPBDHHEO_01372	4.69e-314	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EPBDHHEO_01373	0.0	glyQS	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of glycine to tRNA(Gly)
EPBDHHEO_01374	7.17e-79	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Domain of unknown function (DUF4982)
EPBDHHEO_01375	1.39e-66	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
EPBDHHEO_01376	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EPBDHHEO_01377	2.73e-213	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EPBDHHEO_01378	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EPBDHHEO_01379	2.81e-192	atpH	-	-	C	ko:K02109,ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EPBDHHEO_01380	7.5e-98	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EPBDHHEO_01381	1.21e-40	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EPBDHHEO_01383	3.54e-188	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
EPBDHHEO_01384	2.41e-264	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EPBDHHEO_01386	2.11e-27	-	-	-	S	ko:K09803	-	ko00000	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system
EPBDHHEO_01387	7.29e-54	-	-	-	-	-	-	-	-
EPBDHHEO_01388	0.0	-	-	-	K	-	-	-	RNA polymerase II activating transcription factor binding
EPBDHHEO_01389	0.0	glgE	2.4.99.16	GH13	G	ko:K16147	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
EPBDHHEO_01390	1.13e-118	ppa	3.6.1.1	-	C	ko:K01507	ko00190,map00190	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EPBDHHEO_01392	2.85e-134	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
EPBDHHEO_01393	5.6e-170	-	-	-	-	-	-	-	-
EPBDHHEO_01394	7.59e-173	glnR	-	-	KT	-	-	-	Transcriptional regulatory protein, C terminal
EPBDHHEO_01395	4.88e-161	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EPBDHHEO_01396	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
EPBDHHEO_01397	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
EPBDHHEO_01398	0.0	-	-	-	S	-	-	-	domain protein
EPBDHHEO_01399	9.37e-96	tyrA	5.4.99.5	-	E	ko:K04092	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase type II
EPBDHHEO_01400	2.2e-117	lrp_3	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	helix_turn_helix ASNC type
EPBDHHEO_01401	4.64e-295	-	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K10907,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
EPBDHHEO_01402	0.0	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EPBDHHEO_01403	0.0	-	-	-	H	-	-	-	Flavin containing amine oxidoreductase
EPBDHHEO_01404	1.32e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF2469)
EPBDHHEO_01405	1.38e-251	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
EPBDHHEO_01406	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EPBDHHEO_01407	0.0	gatA	6.3.5.6, 6.3.5.7	-	F	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
EPBDHHEO_01408	3.33e-64	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EPBDHHEO_01409	3.27e-19	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
EPBDHHEO_01410	5.5e-54	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
EPBDHHEO_01411	1.94e-213	trmH	2.1.1.34	-	J	ko:K00556	-	ko00000,ko01000,ko03016	RNA methyltransferase TrmH family
EPBDHHEO_01412	4.99e-164	pyrE1	-	-	F	-	-	-	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EPBDHHEO_01413	1.45e-297	rmuC	-	-	S	ko:K09760	-	ko00000	RmuC family
EPBDHHEO_01414	6.68e-57	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	Metal-sensitive transcriptional repressor
EPBDHHEO_01415	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
EPBDHHEO_01416	0.0	-	-	-	S	ko:K03688	-	ko00000	ABC1 family
EPBDHHEO_01417	3.15e-44	-	-	-	S	-	-	-	granule-associated protein
EPBDHHEO_01418	1.02e-181	cobQ2	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
EPBDHHEO_01419	0.0	murE	-	-	M	-	-	-	Domain of unknown function (DUF1727)
EPBDHHEO_01420	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
EPBDHHEO_01421	0.0	dinF	-	-	V	-	-	-	MatE
EPBDHHEO_01422	0.0	glnD	2.7.7.59	-	O	ko:K00990	ko02020,map02020	ko00000,ko00001,ko01000	Nucleotidyltransferase domain
EPBDHHEO_01423	2.56e-72	glnB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Nitrogen regulatory protein P-II
EPBDHHEO_01424	2.1e-305	amt	-	-	U	ko:K03320	-	ko00000,ko02000	Ammonium Transporter Family
EPBDHHEO_01425	2.48e-276	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
EPBDHHEO_01427	7.87e-171	icaR	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
EPBDHHEO_01428	1.96e-254	-	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	Glycosyltransferase like family 2
EPBDHHEO_01429	0.0	-	-	-	S	-	-	-	Glycosyl hydrolases related to GH101 family, GH129
EPBDHHEO_01430	0.0	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
EPBDHHEO_01431	2.07e-92	-	-	-	O	-	-	-	OsmC-like protein
EPBDHHEO_01432	4.99e-223	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EPBDHHEO_01433	5.46e-165	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	dihydrofolate reductase
EPBDHHEO_01434	2.34e-124	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	low molecular weight
EPBDHHEO_01435	1.27e-249	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
EPBDHHEO_01436	5.58e-61	-	-	-	E	-	-	-	Branched-chain amino acid transport protein (AzlD)
EPBDHHEO_01437	5.06e-145	vex	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
EPBDHHEO_01438	3.58e-266	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
EPBDHHEO_01439	4.37e-289	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
EPBDHHEO_01440	8.73e-15	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
EPBDHHEO_01441	2.68e-22	-	-	-	L	-	-	-	Transposase, Mutator family
EPBDHHEO_01442	4.31e-232	-	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
EPBDHHEO_01443	2.35e-76	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Amidohydrolase family
EPBDHHEO_01444	1.51e-100	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Helix-hairpin-helix motif
EPBDHHEO_01445	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein
EPBDHHEO_01446	6.09e-231	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
EPBDHHEO_01447	3.13e-153	tsaE	-	-	S	ko:K06925	-	ko00000,ko03016	Threonylcarbamoyl adenosine biosynthesis protein TsaE
EPBDHHEO_01448	3.59e-206	yeaZ	-	-	O	ko:K14742	-	ko00000,ko03016	Glycoprotease family
EPBDHHEO_01449	4.23e-135	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	FR47-like protein
EPBDHHEO_01450	1.61e-250	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EPBDHHEO_01452	1.63e-167	-	-	-	M	-	-	-	Peptidase family M23
EPBDHHEO_01453	0.0	fadD1	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
EPBDHHEO_01454	6.61e-277	-	-	-	-	-	-	-	-
EPBDHHEO_01455	0.0	glgX	3.2.1.68	CBM48,GH13	G	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
EPBDHHEO_01456	9.31e-166	-	-	-	L	-	-	-	NUDIX domain
EPBDHHEO_01457	1.09e-220	-	-	-	L	-	-	-	NIF3 (NGG1p interacting factor 3)
EPBDHHEO_01458	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EPBDHHEO_01459	5.44e-161	pdtaR	-	-	T	ko:K22010	-	ko00000,ko00002,ko02022	Response regulator receiver domain protein
EPBDHHEO_01461	8.13e-141	aspA	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
EPBDHHEO_01462	5.21e-91	-	-	-	-	-	-	-	-
EPBDHHEO_01463	9.4e-105	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
EPBDHHEO_01464	5.77e-81	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EPBDHHEO_01466	1.33e-255	ltaE	4.1.2.48	-	E	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Beta-eliminating lyase
EPBDHHEO_01467	1.04e-289	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
EPBDHHEO_01468	0.0	-	-	-	M	-	-	-	Parallel beta-helix repeats
EPBDHHEO_01469	0.0	lacZ6	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
EPBDHHEO_01470	0.0	gph	-	-	G	ko:K16209	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
EPBDHHEO_01472	8.3e-224	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
EPBDHHEO_01473	2.29e-254	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
EPBDHHEO_01474	5.65e-73	-	-	-	S	-	-	-	Domain of unknown function (DUF4190)
EPBDHHEO_01478	1.1e-30	-	-	-	-	-	-	-	-
EPBDHHEO_01479	4.47e-263	-	-	-	S	-	-	-	Short C-terminal domain
EPBDHHEO_01480	2.59e-111	-	-	-	S	-	-	-	Helix-turn-helix
EPBDHHEO_01481	4.07e-85	-	-	-	S	-	-	-	Zincin-like metallopeptidase
EPBDHHEO_01482	1.66e-46	-	-	-	S	ko:K07069	-	ko00000	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
EPBDHHEO_01483	2.1e-49	-	-	-	-	-	-	-	-
EPBDHHEO_01484	1.5e-96	fms	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
EPBDHHEO_01485	4.5e-162	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
EPBDHHEO_01486	0.0	-	2.7.11.1	-	S	ko:K12132	-	ko00000,ko01000,ko01001	PASTA domain
EPBDHHEO_01487	0.0	-	-	-	M	ko:K07272	-	ko00000,ko01000,ko01003,ko01005	Rhamnan synthesis protein F
EPBDHHEO_01488	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
EPBDHHEO_01489	2.18e-266	-	-	-	GM	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
EPBDHHEO_01490	5.96e-167	tagG	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
EPBDHHEO_01491	1.48e-214	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EPBDHHEO_01492	2.67e-199	-	-	-	L	-	-	-	Transposase, Mutator family
EPBDHHEO_01493	4.31e-239	-	-	-	L	-	-	-	HTH-like domain
EPBDHHEO_01494	2.89e-224	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
EPBDHHEO_01495	3.69e-178	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EPBDHHEO_01496	9.33e-153	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
EPBDHHEO_01497	9.24e-288	senX3	2.7.13.3	-	T	ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
EPBDHHEO_01498	4.6e-53	-	-	-	-	-	-	-	-
EPBDHHEO_01499	1.28e-275	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EPBDHHEO_01500	7.1e-230	-	-	-	S	-	-	-	CHAP domain
EPBDHHEO_01501	2.08e-147	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
EPBDHHEO_01502	1.31e-244	-	-	-	T	-	-	-	Universal stress protein family
EPBDHHEO_01503	1.6e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF2442)
EPBDHHEO_01504	1.33e-67	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
EPBDHHEO_01505	0.0	-	-	-	U	-	-	-	Relaxase/Mobilisation nuclease domain
EPBDHHEO_01506	2.23e-222	-	-	-	S	-	-	-	Protein of unknown function (DUF3801)
EPBDHHEO_01507	0.0	-	-	-	-	-	-	-	-
EPBDHHEO_01510	1.36e-131	-	-	-	S	ko:K06895	-	ko00000,ko02000	LysE type translocator
EPBDHHEO_01511	0.0	-	-	-	EK	ko:K05825,ko:K18907	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko00002,ko01000,ko01504,ko03000	Alanine-glyoxylate amino-transferase
EPBDHHEO_01512	2.4e-80	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
EPBDHHEO_01513	3.56e-47	-	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
EPBDHHEO_01514	3.22e-139	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EPBDHHEO_01515	1.22e-226	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
EPBDHHEO_01516	1.61e-108	-	-	-	O	-	-	-	Hsp20/alpha crystallin family
EPBDHHEO_01517	1.3e-137	-	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
EPBDHHEO_01518	7.31e-154	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Conserved hypothetical protein 95
EPBDHHEO_01519	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EPBDHHEO_01520	8.76e-124	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EPBDHHEO_01521	1.27e-294	truB	5.4.99.25	-	J	ko:K03177	-	ko00000,ko01000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EPBDHHEO_01522	1.78e-304	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	riboflavin kinase
EPBDHHEO_01523	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EPBDHHEO_01524	6.9e-142	-	-	-	-	-	-	-	-
EPBDHHEO_01525	5.18e-07	-	-	-	S	-	-	-	Mitochondrial domain of unknown function (DUF1713)
EPBDHHEO_01526	1.28e-162	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EPBDHHEO_01527	4.34e-261	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EPBDHHEO_01528	0.0	-	3.2.1.35	-	G	ko:K01197	ko00531,ko01100,map00531,map01100	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	beta-N-acetylglucosaminidase
EPBDHHEO_01529	0.0	merA	1.16.1.1	-	C	ko:K00520,ko:K21739	-	ko00000,ko01000	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EPBDHHEO_01530	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
EPBDHHEO_01531	5.48e-58	-	-	-	M	-	-	-	Spy0128-like isopeptide containing domain
EPBDHHEO_01532	5.62e-05	-	-	-	O	ko:K18546	-	ko00000,ko01000,ko01002	Peptidase s1 and s6 chymotrypsin hap
EPBDHHEO_01533	0.0	ptsG	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system, glucose-specific IIABC component
EPBDHHEO_01534	3.56e-198	arbG	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
EPBDHHEO_01535	3.25e-273	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
EPBDHHEO_01536	0.0	-	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	5'-nucleotidase, C-terminal domain
EPBDHHEO_01537	1.21e-302	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EPBDHHEO_01539	0.0	-	3.2.1.50	-	G	ko:K01205	ko00531,ko01100,ko04142,map00531,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko04147	Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain
EPBDHHEO_01541	1.29e-122	-	-	-	-	-	-	-	-
EPBDHHEO_01542	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EPBDHHEO_01543	3.38e-232	opcA	-	-	G	-	-	-	Glucose-6-phosphate dehydrogenase subunit
EPBDHHEO_01544	9.67e-180	pgl	3.1.1.31	-	G	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
EPBDHHEO_01545	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EPBDHHEO_01546	1.18e-162	tcsR3	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
EPBDHHEO_01547	0.0	tcsS3	-	-	KT	-	-	-	PspC domain
EPBDHHEO_01548	0.0	pspC	-	-	KT	-	-	-	PspC domain
EPBDHHEO_01549	1.6e-203	-	-	-	-	-	-	-	-
EPBDHHEO_01550	9.55e-146	-	-	-	S	-	-	-	Protein of unknown function (DUF4125)
EPBDHHEO_01551	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4037)
EPBDHHEO_01552	4.31e-277	-	-	-	EGP	ko:K08156,ko:K19577	-	ko00000,ko02000	Major Facilitator Superfamily
EPBDHHEO_01554	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
EPBDHHEO_01556	3.31e-171	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EPBDHHEO_01557	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EPBDHHEO_01558	1.12e-179	ltbR	-	-	K	-	-	-	Transcriptional regulator, IclR family, C-terminal domain protein
EPBDHHEO_01559	9.69e-317	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
EPBDHHEO_01560	1.03e-141	-	-	-	-	-	-	-	-
EPBDHHEO_01561	1.83e-244	cbs	2.5.1.47, 4.2.1.22	-	E	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
EPBDHHEO_01562	3.55e-280	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
EPBDHHEO_01563	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
EPBDHHEO_01564	2.57e-118	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
EPBDHHEO_01565	0.0	tetM	-	-	J	ko:K18220	-	br01600,ko00000,ko01504	Elongation factor G, domain IV
EPBDHHEO_01566	2.28e-86	-	-	-	-	-	-	-	-
EPBDHHEO_01567	5.8e-136	-	-	-	-	-	-	-	-
EPBDHHEO_01568	1.1e-297	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EPBDHHEO_01569	2.05e-177	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
EPBDHHEO_01570	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	CobB/CobQ-like glutamine amidotransferase domain
EPBDHHEO_01571	8.31e-254	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
EPBDHHEO_01572	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
EPBDHHEO_01573	4.9e-264	-	2.7.1.162	-	S	ko:K13059	-	ko00000,ko01000	Phosphotransferase enzyme family
EPBDHHEO_01574	1.23e-275	-	-	-	GK	-	-	-	ROK family
EPBDHHEO_01575	4.48e-228	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
EPBDHHEO_01576	1.57e-199	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EPBDHHEO_01577	2.63e-240	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
EPBDHHEO_01578	8.39e-73	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Bacterial transferase hexapeptide repeat protein
EPBDHHEO_01579	7.44e-151	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Belongs to the SUA5 family
EPBDHHEO_01580	2.14e-260	rfe	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 4
EPBDHHEO_01581	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
EPBDHHEO_01583	2.14e-69	-	-	-	-	-	-	-	-
EPBDHHEO_01584	0.0	-	-	-	K	-	-	-	WYL domain
EPBDHHEO_01585	0.0	ugp	2.7.7.9	-	G	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
EPBDHHEO_01587	1.03e-26	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
EPBDHHEO_01589	9.66e-307	pbuX	-	-	F	ko:K03458	-	ko00000	Permease family
EPBDHHEO_01590	1.54e-137	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
EPBDHHEO_01591	0.0	yrhL	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 9.99
EPBDHHEO_01594	4e-154	mgtC	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
EPBDHHEO_01596	6.19e-263	-	-	-	-	-	-	-	-
EPBDHHEO_01598	2.09e-272	-	-	-	-	-	-	-	-
EPBDHHEO_01601	2.62e-157	-	-	-	U	ko:K12510	-	ko00000,ko02044	Type ii secretion system
EPBDHHEO_01602	1.93e-243	cpaF	-	-	U	ko:K02283	-	ko00000,ko02035,ko02044	Type II IV secretion system protein
EPBDHHEO_01603	2.71e-196	-	-	-	D	-	-	-	bacterial-type flagellum organization
EPBDHHEO_01605	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EPBDHHEO_01606	6.66e-256	mutT	3.6.1.55	-	LT	ko:K03574	-	ko00000,ko01000,ko03400	Phosphoglycerate mutase family
EPBDHHEO_01607	5.26e-130	-	-	-	-	-	-	-	-
EPBDHHEO_01609	6.42e-38	ureD	-	-	O	ko:K03190	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
EPBDHHEO_01610	1.29e-267	-	-	-	S	-	-	-	Glycosyltransferase, group 2 family protein
EPBDHHEO_01611	0.0	-	-	-	-	-	-	-	-
EPBDHHEO_01612	0.00015	-	-	-	-	-	-	-	-
EPBDHHEO_01613	2.41e-37	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	ThiS family
EPBDHHEO_01614	1.93e-211	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
EPBDHHEO_01615	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
EPBDHHEO_01616	0.0	-	-	-	H	-	-	-	Protein of unknown function (DUF4012)
EPBDHHEO_01617	0.0	-	-	-	V	-	-	-	ABC transporter permease
EPBDHHEO_01618	8.04e-270	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
EPBDHHEO_01619	1.98e-177	-	-	-	T	ko:K06950	-	ko00000	HD domain
EPBDHHEO_01620	3.34e-211	-	-	-	S	-	-	-	Glutamine amidotransferase domain
EPBDHHEO_01622	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
EPBDHHEO_01623	7.49e-235	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
EPBDHHEO_01624	2.55e-259	-	-	-	G	ko:K16210	-	ko00000,ko02000	MFS/sugar transport protein
EPBDHHEO_01625	1.18e-51	-	-	-	G	ko:K16210	-	ko00000,ko02000	MFS/sugar transport protein
EPBDHHEO_01627	2.62e-111	-	-	-	K	-	-	-	Transcriptional regulator
EPBDHHEO_01628	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EPBDHHEO_01629	6.3e-169	-	-	-	-	-	-	-	-
EPBDHHEO_01630	1.6e-83	-	-	-	-	-	-	-	-
EPBDHHEO_01631	2.05e-224	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EPBDHHEO_01632	1.54e-162	dedA1	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
EPBDHHEO_01634	2.47e-179	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
EPBDHHEO_01635	0.0	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	BNR Asp-box repeat
EPBDHHEO_01636	0.0	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	BNR repeat-like domain
EPBDHHEO_01637	9.12e-112	hspR	-	-	K	ko:K13640	-	ko00000,ko03000	transcriptional regulator, MerR family
EPBDHHEO_01638	2.72e-236	dnaJ	-	-	O	ko:K03686,ko:K05516	-	ko00000,ko03029,ko03036,ko03110	DnaJ molecular chaperone homology domain
EPBDHHEO_01639	8.46e-88	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EPBDHHEO_01640	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
EPBDHHEO_01641	0.0	strK	3.1.3.1, 3.1.3.39	-	P	ko:K01077,ko:K04342	ko00521,ko00730,ko00790,ko01100,ko01130,ko02020,map00521,map00730,map00790,map01100,map01130,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Alkaline phosphatase homologues
EPBDHHEO_01642	9.58e-244	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
EPBDHHEO_01645	1.84e-180	gpm2	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
EPBDHHEO_01646	5.82e-89	-	-	-	S	-	-	-	Protein of unknown function (DUF4235)
EPBDHHEO_01647	7.71e-182	nfrA	-	-	C	-	-	-	Nitroreductase family
EPBDHHEO_01648	5.86e-299	-	-	-	S	-	-	-	Domain of Unknown Function (DUF349)
EPBDHHEO_01649	0.0	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Histidyl-tRNA synthetase
EPBDHHEO_01650	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EPBDHHEO_01651	8.09e-265	-	-	-	KL	-	-	-	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EPBDHHEO_01652	1.34e-314	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
EPBDHHEO_01653	3.93e-223	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
EPBDHHEO_01654	1.93e-215	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	ABC transporter permease
EPBDHHEO_01657	6.54e-86	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
EPBDHHEO_01658	6.65e-126	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
EPBDHHEO_01659	0.0	gltX	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EPBDHHEO_01662	1.18e-99	-	-	-	-	-	-	-	-
EPBDHHEO_01663	1.2e-83	-	-	-	D	-	-	-	MobA/MobL family
EPBDHHEO_01664	2.58e-63	-	-	-	L	ko:K07483	-	ko00000	Transposase
EPBDHHEO_01665	1.39e-205	tnp3521a2	-	-	L	-	-	-	Integrase core domain
EPBDHHEO_01666	5.58e-33	-	-	-	S	-	-	-	Adenine-specific methyltransferase EcoRI
EPBDHHEO_01667	9.3e-53	-	-	-	-	-	-	-	-
EPBDHHEO_01668	4.02e-91	gloA	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EPBDHHEO_01669	9.82e-45	-	-	-	-	-	-	-	-
EPBDHHEO_01670	0.0	-	-	-	L	ko:K03502	-	ko00000,ko03400	DNA-damage repair protein (DNA polymerase IV) K00961
EPBDHHEO_01671	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EPBDHHEO_01672	0.0	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
EPBDHHEO_01673	4.94e-287	-	-	-	-	-	-	-	-
EPBDHHEO_01674	7.79e-108	-	-	-	-	-	-	-	-
EPBDHHEO_01675	0.0	-	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	DNA topoisomerase
EPBDHHEO_01676	5.11e-85	-	-	-	-	-	-	-	-
EPBDHHEO_01677	5.27e-69	-	-	-	-	-	-	-	-
EPBDHHEO_01678	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
EPBDHHEO_01679	6.79e-231	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
EPBDHHEO_01680	1.08e-146	-	-	-	-	-	-	-	-
EPBDHHEO_01681	2.2e-140	-	-	-	S	-	-	-	Protein of unknown function (DUF4230)
EPBDHHEO_01682	3.04e-132	nnrE	-	-	L	-	-	-	Uracil DNA glycosylase superfamily
EPBDHHEO_01683	8.74e-23	-	-	-	K	-	-	-	DNA-binding transcription factor activity
EPBDHHEO_01684	5.5e-199	-	-	-	S	-	-	-	Aldo/keto reductase family
EPBDHHEO_01685	8.97e-223	dkgV	-	-	C	-	-	-	Aldo/keto reductase family
EPBDHHEO_01686	1.5e-100	-	-	-	S	-	-	-	Domain of unknown function (DUF4186)
EPBDHHEO_01688	2.68e-232	-	-	-	S	-	-	-	Protein conserved in bacteria
EPBDHHEO_01689	0.0	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EPBDHHEO_01690	2.16e-284	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EPBDHHEO_01691	1.08e-145	hisB	3.1.3.15, 4.2.1.19	-	E	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Imidazoleglycerol-phosphate dehydratase
EPBDHHEO_01692	1.84e-151	-	-	-	-	-	-	-	-
EPBDHHEO_01693	3.31e-157	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EPBDHHEO_01694	4.81e-167	hisA	5.3.1.16, 5.3.1.24	-	E	ko:K01814,ko:K01817	ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Histidine biosynthesis protein
EPBDHHEO_01695	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2252)
EPBDHHEO_01696	0.0	glnA2	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
EPBDHHEO_01697	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
EPBDHHEO_01699	1.2e-241	-	-	-	M	-	-	-	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
EPBDHHEO_01700	0.0	hrpA	3.6.4.13	-	L	ko:K03578	-	ko00000,ko01000	Helicase associated domain (HA2) Add an annotation
EPBDHHEO_01701	2.51e-157	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase (PrmA)
EPBDHHEO_01702	3.25e-222	-	-	-	-	-	-	-	-
EPBDHHEO_01703	0.0	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EPBDHHEO_01704	1.13e-225	ldh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
EPBDHHEO_01705	3.88e-213	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EPBDHHEO_01706	3.03e-166	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EPBDHHEO_01707	2.4e-65	-	-	-	M	-	-	-	Lysin motif
EPBDHHEO_01708	3.1e-108	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EPBDHHEO_01709	1.37e-291	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
EPBDHHEO_01710	0.0	-	-	-	L	-	-	-	DNA helicase
EPBDHHEO_01711	8.85e-118	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
EPBDHHEO_01712	1.7e-243	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
EPBDHHEO_01713	2.29e-96	-	-	-	D	-	-	-	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EPBDHHEO_01714	0.0	ftsI	3.4.16.4	-	M	ko:K03587	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Penicillin-binding protein, transpeptidase domain protein
EPBDHHEO_01715	2.48e-231	-	-	-	M	-	-	-	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EPBDHHEO_01716	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
EPBDHHEO_01717	1.52e-261	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EPBDHHEO_01718	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EPBDHHEO_01719	4.49e-297	ftsW	2.4.1.227	GT28	D	ko:K02563,ko:K03588	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011,ko02000,ko03036	Belongs to the SEDS family
EPBDHHEO_01720	2.58e-275	murG	2.4.1.227, 6.3.2.8	GT28	M	ko:K01924,ko:K02563	ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EPBDHHEO_01721	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
EPBDHHEO_01722	0.0	-	-	-	L	-	-	-	Recombinase
EPBDHHEO_01723	5.52e-130	-	3.1.21.3	-	L	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
EPBDHHEO_01724	9.24e-187	-	-	-	-	-	-	-	-
EPBDHHEO_01725	0.0	-	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	modification (methylase) protein of type I restriction-modification system K03427
EPBDHHEO_01726	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
EPBDHHEO_01727	1.42e-39	-	-	-	-	-	-	-	-
EPBDHHEO_01728	2.1e-122	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Involved in chromosome partitioning
EPBDHHEO_01729	2.44e-182	-	-	-	S	-	-	-	Relaxase/Mobilisation nuclease domain
EPBDHHEO_01731	2.42e-182	nt5e	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
EPBDHHEO_01732	6.43e-81	rbpA	-	-	K	-	-	-	Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
EPBDHHEO_01733	1.21e-262	helY	-	-	L	ko:K03727	-	ko00000,ko01000	DEAD DEAH box helicase
EPBDHHEO_01734	2.49e-230	-	-	-	S	ko:K21688	-	ko00000	G5
EPBDHHEO_01735	2.57e-78	trxA	1.8.1.9	-	O	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	ko00000,ko00001,ko01000,ko03110	Belongs to the thioredoxin family
EPBDHHEO_01736	4.72e-153	-	-	-	F	-	-	-	Domain of unknown function (DUF4916)
EPBDHHEO_01737	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase
EPBDHHEO_01738	3.18e-204	terC	-	-	P	ko:K05794	-	ko00000	Integral membrane protein, TerC family
EPBDHHEO_01739	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	Cation transporting ATPase, C-terminus
EPBDHHEO_01740	6.57e-97	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EPBDHHEO_01741	1.82e-179	hisF	4.1.3.27	-	E	ko:K01657,ko:K02500	ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
EPBDHHEO_01742	6.52e-173	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
EPBDHHEO_01743	1.71e-144	pncA	3.5.1.19	-	Q	ko:K08281	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Isochorismatase family
EPBDHHEO_01745	3.72e-182	gnpA	2.4.1.211	-	S	ko:K15533	-	ko00000,ko01000	Lacto-N-biose phosphorylase C-terminal domain
EPBDHHEO_01746	2.69e-82	psp1	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	Endoribonuclease L-PSP
EPBDHHEO_01747	0.0	trpE	4.1.3.27	-	E	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EPBDHHEO_01748	1.58e-201	-	2.7.1.95	-	F	ko:K00897	-	ko00000,ko01000,ko01504	Phosphotransferase enzyme family
EPBDHHEO_01749	5.71e-78	dkg	-	-	S	-	-	-	Oxidoreductase, aldo keto reductase family protein
EPBDHHEO_01750	7.48e-186	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
EPBDHHEO_01751	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
EPBDHHEO_01752	2.24e-139	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EPBDHHEO_01753	0.0	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
EPBDHHEO_01754	1.41e-209	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EPBDHHEO_01755	1.55e-232	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
EPBDHHEO_01756	6.96e-211	-	-	-	P	ko:K02074	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
EPBDHHEO_01757	2.15e-177	znuB	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
EPBDHHEO_01758	3.12e-109	ispF	2.7.7.60, 4.6.1.12	-	H	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
EPBDHHEO_01759	1.99e-131	carD	-	-	K	ko:K07736	-	ko00000,ko03000	CarD-like/TRCF domain
EPBDHHEO_01760	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EPBDHHEO_01761	9.32e-164	cseB	-	-	T	-	-	-	Response regulator receiver domain protein
EPBDHHEO_01762	5.91e-259	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
EPBDHHEO_01763	1.85e-92	umuD	-	-	KT	ko:K03503	-	ko00000,ko01000,ko01002,ko03400	Peptidase S24-like
EPBDHHEO_01764	3.04e-167	pyrE_1	-	-	S	-	-	-	Phosphoribosyl transferase domain
EPBDHHEO_01765	4.52e-198	-	-	-	T	-	-	-	Eukaryotic phosphomannomutase
EPBDHHEO_01766	1.05e-85	-	-	-	S	-	-	-	Zincin-like metallopeptidase
EPBDHHEO_01767	0.0	-	-	-	-	-	-	-	-
EPBDHHEO_01768	0.0	-	-	-	S	-	-	-	Glycosyl transferase, family 2
EPBDHHEO_01769	2.82e-72	whiB2	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
EPBDHHEO_01770	0.0	lytR2	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
EPBDHHEO_01771	0.0	-	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK/SpoIIIE family
EPBDHHEO_01772	1.35e-60	whiB	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
EPBDHHEO_01773	0.0	pdtaS	2.7.13.3	-	T	ko:K00936	-	ko00000,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
EPBDHHEO_01774	1.95e-193	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	Haemolysin-III related
EPBDHHEO_01776	1.67e-104	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
EPBDHHEO_01777	7.02e-94	fkbP	5.2.1.8	-	G	ko:K01802	-	ko00000,ko01000	Peptidyl-prolyl cis-trans
EPBDHHEO_01778	0.0	sdaA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase alpha chain
EPBDHHEO_01779	4.4e-126	-	-	-	-	-	-	-	-
EPBDHHEO_01781	2.41e-233	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
EPBDHHEO_01782	8.88e-138	-	-	-	S	ko:K09009	-	ko00000	Protein of unknown function (DUF501)
EPBDHHEO_01783	4.19e-131	-	-	-	D	-	-	-	Septum formation initiator
EPBDHHEO_01784	7.41e-315	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
EPBDHHEO_01785	2.04e-194	pabC	2.6.1.42, 2.6.1.85, 4.1.3.38	-	E	ko:K00826,ko:K01665,ko:K02619,ko:K03342	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	branched-chain-amino-acid transaminase activity
EPBDHHEO_01786	0.0	pabB	2.6.1.85, 4.1.3.27, 4.1.3.38	-	EH	ko:K01657,ko:K01665,ko:K03342,ko:K13950	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000,ko01007	chorismate binding enzyme
EPBDHHEO_01787	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EPBDHHEO_01788	3.48e-146	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
EPBDHHEO_01789	9.1e-127	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
EPBDHHEO_01790	1.97e-186	rfbB2	3.6.3.40	-	GM	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
EPBDHHEO_01791	1.2e-194	-	-	-	GM	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
EPBDHHEO_01792	1.72e-252	-	-	-	GM	-	-	-	GDP-mannose 4,6 dehydratase
EPBDHHEO_01793	2.58e-165	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
EPBDHHEO_01796	6.6e-277	-	-	-	I	ko:K13663	-	ko00000,ko01000	transferase activity, transferring acyl groups other than amino-acyl groups
EPBDHHEO_01797	0.0	-	2.7.8.14, 2.7.8.47	-	M	ko:K18704	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
EPBDHHEO_01798	2.04e-263	-	2.7.8.14, 2.7.8.47	-	M	ko:K18704	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase