ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
NLHLMEME_00001 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Anaerobic ribonucleoside-triphosphate reductase
NLHLMEME_00002 0.0 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NLHLMEME_00003 3.06e-54 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NLHLMEME_00004 4.67e-116 ywrO - - S - - - Flavodoxin-like fold
NLHLMEME_00005 0.0 fadD3 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
NLHLMEME_00006 8.52e-91 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NLHLMEME_00007 7.41e-102 - - - F - - - Nucleoside 2-deoxyribosyltransferase
NLHLMEME_00009 1.21e-268 - - - S ko:K18353 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01504 Endonuclease/Exonuclease/phosphatase family
NLHLMEME_00010 9.73e-228 ppx1 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 Ppx/GppA phosphatase family
NLHLMEME_00011 3.68e-298 aspB 2.6.1.1, 2.6.1.2, 2.6.1.66 - E ko:K00812,ko:K08969,ko:K14260 ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class-V
NLHLMEME_00012 2.14e-257 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
NLHLMEME_00013 5.24e-116 vsr - - L ko:K07458 - ko00000,ko01000,ko03400 May nick specific sequences that contain T G mispairs resulting from m5C-deamination
NLHLMEME_00014 1.5e-129 - - - K - - - Acetyltransferase (GNAT) domain
NLHLMEME_00015 0.0 - - - KL - - - Psort location Cytoplasmic, score 8.87
NLHLMEME_00016 1.24e-218 dapD 2.3.1.117 - E ko:K00674 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
NLHLMEME_00017 9.67e-317 gltA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Citrate synthase, C-terminal domain
NLHLMEME_00018 1.25e-192 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
NLHLMEME_00019 2.91e-199 - - - S - - - Short repeat of unknown function (DUF308)
NLHLMEME_00020 0.0 pepO 3.4.24.11, 3.4.24.71 - O ko:K01389,ko:K01415,ko:K07386 ko04614,ko04640,ko04974,ko05010,map04614,map04640,map04974,map05010 ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 Peptidase family M13
NLHLMEME_00021 7.68e-151 ssb2 - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-strand binding protein family
NLHLMEME_00022 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NLHLMEME_00023 2.41e-196 - 1.97.1.4 - O ko:K04069 - ko00000,ko01000 Radical SAM superfamily
NLHLMEME_00024 0.0 - - - L - - - PIF1-like helicase
NLHLMEME_00025 3.86e-156 orn - - L ko:K13288 ko03008,map03008 ko00000,ko00001,ko01000,ko03009,ko03019 3'-to-5' exoribonuclease specific for small oligoribonucleotides
NLHLMEME_00026 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NLHLMEME_00027 1.44e-276 rfe 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 Glycosyl transferase family 4
NLHLMEME_00028 2.92e-153 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Belongs to the SUA5 family
NLHLMEME_00029 9.68e-159 livF - - E ko:K01995,ko:K01996 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
NLHLMEME_00030 4.72e-206 livG - - E ko:K01995 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid ATP-binding cassette transporter
NLHLMEME_00031 1.25e-240 - - - U ko:K01998 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NLHLMEME_00032 1.08e-196 - - - U ko:K01997 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NLHLMEME_00033 4.61e-272 - - - E ko:K01999 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Receptor family ligand binding region
NLHLMEME_00034 6.22e-210 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NLHLMEME_00035 3.49e-248 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NLHLMEME_00036 6.44e-49 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
NLHLMEME_00038 3.86e-136 - - - U - - - Drug resistance MFS transporter, drug H antiporter-2 family
NLHLMEME_00039 9.48e-194 - - - - - - - -
NLHLMEME_00040 7.76e-89 fms 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
NLHLMEME_00041 9.56e-208 dkg - - S - - - Oxidoreductase, aldo keto reductase family protein
NLHLMEME_00042 4.17e-119 - - - K - - - Winged helix DNA-binding domain
NLHLMEME_00043 7.97e-224 glkA 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
NLHLMEME_00045 0.0 - - - EGP - - - Major Facilitator Superfamily
NLHLMEME_00046 0.0 yjjK - - S - - - ATP-binding cassette protein, ChvD family
NLHLMEME_00047 8.55e-216 tesB - - I ko:K10805 ko01040,map01040 ko00000,ko00001,ko01000,ko01004 Thioesterase-like superfamily
NLHLMEME_00048 3.27e-112 - - - S - - - Protein of unknown function (DUF3180)
NLHLMEME_00049 1.37e-288 folK 2.7.6.3, 4.1.2.25 - H ko:K00950,ko:K13940 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NLHLMEME_00050 4.72e-206 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NLHLMEME_00051 1.9e-153 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
NLHLMEME_00052 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NLHLMEME_00053 2.66e-126 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
NLHLMEME_00054 3.35e-268 tilS 2.4.2.8, 6.3.4.19 - J ko:K00760,ko:K04075 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NLHLMEME_00055 0.0 dacB 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-Ala-D-Ala carboxypeptidase 3 (S13) family
NLHLMEME_00056 0.0 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
NLHLMEME_00057 8.2e-246 natA - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NLHLMEME_00058 7.16e-298 - - - M - - - Glycosyl transferase family 21
NLHLMEME_00059 0.0 - - - S - - - AI-2E family transporter
NLHLMEME_00060 1.09e-226 - - - M - - - Glycosyltransferase like family 2
NLHLMEME_00061 7.05e-270 fucO 1.1.1.77, 1.1.99.37, 1.2.98.1 - C ko:K00048,ko:K17067 ko00625,ko00630,ko00640,ko00680,ko01120,ko01200,map00625,map00630,map00640,map00680,map01120,map01200 ko00000,ko00001,ko01000 Iron-containing alcohol dehydrogenase
NLHLMEME_00062 0.0 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 Mycolic acid cyclopropane synthetase
NLHLMEME_00065 1.16e-213 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NLHLMEME_00068 1.19e-15 - - - S - - - Helix-turn-helix domain
NLHLMEME_00069 9.15e-129 - - - S - - - Helix-turn-helix domain
NLHLMEME_00070 8.12e-106 - - - S - - - Helix-turn-helix domain
NLHLMEME_00071 1.11e-106 - - - S ko:K18955 - ko00000,ko03000 Transcription factor WhiB
NLHLMEME_00072 3.42e-94 - - - D ko:K03496 - ko00000,ko03036,ko04812 AAA domain
NLHLMEME_00073 1.19e-50 - - - - - - - -
NLHLMEME_00074 0.0 - - - S - - - ATPases associated with a variety of cellular activities
NLHLMEME_00075 7.27e-121 - - - K - - - FR47-like protein
NLHLMEME_00076 2.32e-152 - 3.1.3.3 - E ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01009 haloacid dehalogenase-like hydrolase
NLHLMEME_00077 0.0 - - - D - - - Cell surface antigen C-terminus
NLHLMEME_00078 1.17e-176 bltR - - K ko:K19575,ko:K21089,ko:K21972,ko:K22491 ko02026,map02026 ko00000,ko00001,ko00002,ko03000 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
NLHLMEME_00079 5.38e-251 - 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NLHLMEME_00080 1.18e-116 - - - - - - - -
NLHLMEME_00082 7.97e-88 - - - S - - - Helix-turn-helix domain
NLHLMEME_00083 7.65e-136 - - - S - - - PIN domain
NLHLMEME_00084 1.96e-314 - - - - - - - -
NLHLMEME_00086 1.8e-257 - - - L - - - Transposase, Mutator family
NLHLMEME_00087 4.48e-52 - - - - - - - -
NLHLMEME_00088 2.88e-188 - - - - - - - -
NLHLMEME_00089 3.73e-56 - - - S - - - PrgI family protein
NLHLMEME_00090 0.0 - - - U - - - type IV secretory pathway VirB4
NLHLMEME_00091 4.85e-257 - - - M - - - CHAP domain
NLHLMEME_00092 9.3e-265 - - - - - - - -
NLHLMEME_00093 1.65e-241 - - - LU ko:K04096 - ko00000 DNA recombination-mediator protein A
NLHLMEME_00094 1.65e-204 - - - S - - - competence protein
NLHLMEME_00095 0.0 - 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 UvrD/REP helicase N-terminal domain
NLHLMEME_00096 0.0 - - - L ko:K07459 - ko00000 AAA ATPase domain
NLHLMEME_00097 0.0 - - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 Type IV secretory system Conjugative DNA transfer
NLHLMEME_00099 9.17e-70 - - - - - - - -
NLHLMEME_00100 2.73e-287 - - - S - - - Antirestriction protein (ArdA)
NLHLMEME_00101 7.08e-148 - - - - - - - -
NLHLMEME_00102 4.78e-191 - - - S - - - Protein of unknown function (DUF3801)
NLHLMEME_00103 0.0 - - - U - - - Relaxase/Mobilisation nuclease domain
NLHLMEME_00104 1.94e-91 - - - S - - - Bacterial mobilisation protein (MobC)
NLHLMEME_00105 1.87e-81 - - - - - - - -
NLHLMEME_00106 1.83e-61 - - - - - - - -
NLHLMEME_00107 0.0 - - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 ParB-like nuclease domain
NLHLMEME_00108 3.43e-139 - - - S - - - Domain of unknown function (DUF4192)
NLHLMEME_00109 3.29e-101 - - - S - - - Nucleotidyltransferase domain
NLHLMEME_00110 3.84e-61 intA - - L - - - Phage integrase family
NLHLMEME_00111 6.06e-253 intA - - L - - - Phage integrase family
NLHLMEME_00112 4.42e-19 - - - L - - - Phage integrase family
NLHLMEME_00113 1.82e-15 - - - M - - - Cell surface antigen C-terminus
NLHLMEME_00114 0.0 gph - - G ko:K16209 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
NLHLMEME_00115 0.0 lacZ6 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
NLHLMEME_00116 2.07e-236 - - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
NLHLMEME_00117 1.32e-26 - - - L - - - Helix-turn-helix domain
NLHLMEME_00118 0.0 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
NLHLMEME_00119 3.43e-281 - - - GK - - - ROK family
NLHLMEME_00120 0.0 - - - G - - - Glycosyl hydrolase family 20, domain 2
NLHLMEME_00121 1.22e-10 - - - L - - - HTH-like domain
NLHLMEME_00122 2.94e-287 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
NLHLMEME_00123 1.37e-270 - - - V ko:K02004 - ko00000,ko00002,ko02000 Efflux ABC transporter, permease protein
NLHLMEME_00124 9.79e-143 vex - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NLHLMEME_00125 2.43e-15 - - - E - - - AzlC protein
NLHLMEME_00126 3.01e-127 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 low molecular weight
NLHLMEME_00127 2.16e-164 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 dihydrofolate reductase
NLHLMEME_00128 1.73e-214 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NLHLMEME_00129 1.85e-95 - - - O - - - OsmC-like protein
NLHLMEME_00131 7.51e-239 - - - T - - - Universal stress protein family
NLHLMEME_00132 2e-138 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
NLHLMEME_00133 1.45e-138 - - - M - - - NlpC/P60 family
NLHLMEME_00134 2.54e-217 - - - S - - - CHAP domain
NLHLMEME_00135 1.43e-271 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NLHLMEME_00136 6.59e-44 - - - - - - - -
NLHLMEME_00137 3.91e-240 senX3 2.7.13.3 - T ko:K07768 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
NLHLMEME_00138 6.31e-150 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
NLHLMEME_00139 3.9e-178 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NLHLMEME_00140 3.23e-221 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
NLHLMEME_00141 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
NLHLMEME_00143 1.02e-280 - - - EGP ko:K08156,ko:K19577 - ko00000,ko02000 Major Facilitator Superfamily
NLHLMEME_00144 0.0 - - - S - - - Domain of unknown function (DUF4037)
NLHLMEME_00145 4.35e-150 - - - S - - - Protein of unknown function (DUF4125)
NLHLMEME_00146 0.0 - - - S ko:K06889 - ko00000 alpha beta
NLHLMEME_00147 1.41e-105 - - - - - - - -
NLHLMEME_00148 0.0 pspC - - KT - - - PspC domain
NLHLMEME_00149 1.64e-300 tcsS3 - - KT - - - PspC domain
NLHLMEME_00150 2.47e-153 tcsR3 - - K - - - helix_turn_helix, Lux Regulon
NLHLMEME_00151 4.59e-226 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
NLHLMEME_00152 1.7e-261 - 2.7.1.162 - S ko:K13059 - ko00000,ko01000 Phosphotransferase enzyme family
NLHLMEME_00153 0.0 gnpA 2.4.1.211 - S ko:K15533 - ko00000,ko01000 Lacto-N-biose phosphorylase C-terminal domain
NLHLMEME_00154 5.76e-217 - - - G ko:K02026 - ko00000,ko00002,ko02000 ABC transporter permease
NLHLMEME_00155 3.93e-223 - - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NLHLMEME_00156 0.0 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
NLHLMEME_00158 1.47e-307 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NLHLMEME_00159 6.53e-271 - - - I - - - Diacylglycerol kinase catalytic domain
NLHLMEME_00160 1.58e-209 arbG - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
NLHLMEME_00161 0.0 ptsG - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system, glucose-specific IIABC component
NLHLMEME_00162 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
NLHLMEME_00163 4.45e-252 - - - S - - - Protein conserved in bacteria
NLHLMEME_00164 1.23e-96 - - - K - - - Transcriptional regulator
NLHLMEME_00165 0.0 merA 1.16.1.1 - C ko:K00520,ko:K21739 - ko00000,ko01000 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NLHLMEME_00166 1.06e-239 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NLHLMEME_00167 4.47e-163 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NLHLMEME_00168 5.05e-07 - - - S - - - Mitochondrial domain of unknown function (DUF1713)
NLHLMEME_00169 4.12e-133 - - - - - - - -
NLHLMEME_00170 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NLHLMEME_00171 1.01e-278 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 riboflavin kinase
NLHLMEME_00172 1.64e-281 truB 5.4.99.25 - J ko:K03177 - ko00000,ko01000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NLHLMEME_00173 3.5e-107 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NLHLMEME_00174 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NLHLMEME_00175 5.54e-244 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
NLHLMEME_00176 5.82e-164 - - - - - - - -
NLHLMEME_00177 7.58e-97 - - - K - - - helix_turn _helix lactose operon repressor
NLHLMEME_00179 1.25e-195 - - - E - - - Transglutaminase/protease-like homologues
NLHLMEME_00180 0.0 gcs2 - - S ko:K06048 - ko00000,ko01000 A circularly permuted ATPgrasp
NLHLMEME_00181 1.27e-218 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NLHLMEME_00182 5.53e-89 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
NLHLMEME_00183 1.2e-232 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NLHLMEME_00184 7.34e-86 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NLHLMEME_00185 2e-82 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NLHLMEME_00186 1.47e-20 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
NLHLMEME_00187 6.91e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NLHLMEME_00188 2.57e-128 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NLHLMEME_00189 9.34e-317 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NLHLMEME_00190 8.81e-98 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
NLHLMEME_00191 3.26e-36 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30p/L7e
NLHLMEME_00192 2.25e-129 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NLHLMEME_00193 3.09e-76 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NLHLMEME_00194 1.33e-122 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NLHLMEME_00195 3.17e-90 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NLHLMEME_00196 7.06e-40 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NLHLMEME_00197 1.95e-134 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NLHLMEME_00198 5.4e-69 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NLHLMEME_00199 2.55e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NLHLMEME_00200 1.11e-54 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NLHLMEME_00201 1.97e-49 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
NLHLMEME_00202 3.85e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NLHLMEME_00203 1.85e-156 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NLHLMEME_00204 1.09e-74 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NLHLMEME_00205 1.4e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NLHLMEME_00206 3.85e-195 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NLHLMEME_00207 2.54e-61 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NLHLMEME_00208 9.78e-151 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
NLHLMEME_00209 1.11e-149 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NLHLMEME_00210 9.35e-68 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
NLHLMEME_00211 3.82e-176 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
NLHLMEME_00212 7.26e-185 - - - S - - - YwiC-like protein
NLHLMEME_00213 0.0 adhE 1.1.1.1, 1.2.1.10, 1.2.1.81 - C ko:K04072,ko:K15515 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
NLHLMEME_00214 2.64e-217 - - - K - - - helix_turn_helix, arabinose operon control protein
NLHLMEME_00215 6.77e-247 - 1.1.1.9 - C ko:K05351 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Zinc-binding dehydrogenase
NLHLMEME_00216 1.73e-248 csbX - - EGP - - - Major Facilitator Superfamily
NLHLMEME_00217 9.79e-275 - - - GK - - - transcriptional repressor of nag (N-acetylglucosamine) operon K02565
NLHLMEME_00218 2.66e-97 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NLHLMEME_00219 3.04e-296 csbX - - EGP - - - Major Facilitator Superfamily
NLHLMEME_00220 2.47e-227 - 1.1.1.1, 1.1.1.287, 1.6.5.5 - C ko:K00001,ko:K00344,ko:K17818 ko00010,ko00040,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding dehydrogenase
NLHLMEME_00221 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G ko:K01214,ko:K02438 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 13 family
NLHLMEME_00222 9.6e-106 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
NLHLMEME_00223 5.33e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NLHLMEME_00224 0.0 malQ 2.4.1.25 GH77 G ko:K00705 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 4-alpha-glucanotransferase
NLHLMEME_00225 9.47e-152 - - - - - - - -
NLHLMEME_00226 6.88e-144 yigZ - - S - - - Uncharacterized protein family UPF0029
NLHLMEME_00227 1.48e-236 pdxB - - EH - - - Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NLHLMEME_00228 5.98e-147 - - - M ko:K07282 - ko00000 Bacterial capsule synthesis protein PGA_cap
NLHLMEME_00229 1.16e-311 - 3.2.1.21 - G ko:K05350 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Glycosyl hydrolase family 1
NLHLMEME_00230 5.08e-205 - - - U ko:K02026,ko:K10190 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NLHLMEME_00231 2.42e-208 - - - U ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NLHLMEME_00232 1.09e-311 - - - G ko:K02027,ko:K10227 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
NLHLMEME_00233 7.41e-277 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
NLHLMEME_00234 2.08e-30 - - - - - - - -
NLHLMEME_00236 1.02e-80 - - - S ko:K11939 - ko00000,ko02000 EamA-like transporter family
NLHLMEME_00237 4.03e-28 - - - S ko:K11939 - ko00000,ko02000 EamA-like transporter family
NLHLMEME_00238 2.57e-304 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NLHLMEME_00239 2.53e-285 dapC - - E - - - Aminotransferase class I and II
NLHLMEME_00240 4.51e-79 fdxA - - C ko:K05524 - ko00000 4Fe-4S binding domain
NLHLMEME_00241 0.0 - - - E ko:K03294 - ko00000 aromatic amino acid transport protein AroP K03293
NLHLMEME_00242 4.96e-289 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
NLHLMEME_00243 1.03e-34 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L33
NLHLMEME_00247 1.73e-63 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NLHLMEME_00248 1.13e-184 - - - - - - - -
NLHLMEME_00249 7.07e-149 rimJ 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
NLHLMEME_00250 7.23e-79 ygfA 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 5-formyltetrahydrofolate cyclo-ligase family
NLHLMEME_00251 6.24e-43 - - - S - - - Putative regulatory protein
NLHLMEME_00252 1.92e-120 - - - NO - - - SAF
NLHLMEME_00253 6.79e-24 - - - L - - - Superfamily I DNA and RNA helicases and helicase subunits
NLHLMEME_00254 0.0 - - - L - - - Superfamily I DNA and RNA helicases and helicase subunits
NLHLMEME_00255 1.04e-281 - - - T - - - Forkhead associated domain
NLHLMEME_00256 1.06e-73 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NLHLMEME_00257 2.41e-113 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NLHLMEME_00258 2.92e-188 - - - S - - - alpha beta
NLHLMEME_00259 0.0 - - - S ko:K06901 - ko00000,ko02000 Permease family
NLHLMEME_00260 4.51e-190 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NLHLMEME_00261 1.86e-221 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
NLHLMEME_00262 9.47e-212 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
NLHLMEME_00263 2.32e-260 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import
NLHLMEME_00264 8.69e-182 regX3 - - KT ko:K07776 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
NLHLMEME_00265 1.22e-276 phoR 2.7.13.3 - T ko:K07636,ko:K07768 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
NLHLMEME_00266 7.16e-308 - - - EGP - - - Sugar (and other) transporter
NLHLMEME_00267 2.11e-159 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NLHLMEME_00268 9.45e-300 aroG 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NLHLMEME_00269 9.77e-279 aroG 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NLHLMEME_00270 0.0 pepC2 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
NLHLMEME_00271 6.94e-120 - - - D - - - nuclear chromosome segregation
NLHLMEME_00272 5.05e-161 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NLHLMEME_00273 7.71e-193 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60 - I ko:K00991,ko:K21681 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
NLHLMEME_00274 6.09e-254 yfiH - - Q ko:K05810 - ko00000,ko01000 Multi-copper polyphenol oxidoreductase laccase
NLHLMEME_00275 0.0 - - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase family U32 C-terminal domain
NLHLMEME_00276 7.12e-227 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
NLHLMEME_00277 4.75e-132 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Conserved hypothetical protein 95
NLHLMEME_00278 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 helicase superfamily c-terminal domain
NLHLMEME_00279 1.05e-40 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal L28 family
NLHLMEME_00280 2.28e-250 - - - G - - - pfkB family carbohydrate kinase
NLHLMEME_00281 9.23e-305 - - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
NLHLMEME_00282 2.28e-168 - - - K - - - helix_turn_helix, mercury resistance
NLHLMEME_00283 2.08e-81 - - - T - - - Toxic component of a toxin-antitoxin (TA) module
NLHLMEME_00284 7.21e-72 - - - L - - - RelB antitoxin
NLHLMEME_00285 2.78e-33 yxiO - - G ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Major facilitator Superfamily
NLHLMEME_00286 6.83e-252 - - - K - - - Helix-turn-helix XRE-family like proteins
NLHLMEME_00287 2.52e-149 - - - S - - - Alpha/beta hydrolase family
NLHLMEME_00291 3.07e-20 - - - EGP - - - Transporter major facilitator family protein
NLHLMEME_00292 7.09e-59 - - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
NLHLMEME_00294 0.0 pccB - - I - - - Carboxyl transferase domain
NLHLMEME_00295 0.0 accC 6.3.4.14, 6.4.1.2, 6.4.1.3 - I ko:K11263 ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase L chain, ATP binding domain protein
NLHLMEME_00296 4.1e-120 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
NLHLMEME_00297 1.09e-193 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Biotin/lipoate A/B protein ligase family
NLHLMEME_00298 0.0 - - - - - - - -
NLHLMEME_00299 2.16e-210 - - - QT - - - PucR C-terminal helix-turn-helix domain
NLHLMEME_00300 1.75e-159 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NLHLMEME_00301 2.38e-94 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NLHLMEME_00302 1.99e-176 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
NLHLMEME_00303 5.79e-43 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NLHLMEME_00305 1.95e-292 aspC 2.6.1.1, 2.6.1.2, 2.6.1.66 - E ko:K00812,ko:K08969,ko:K14260 ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 DegT/DnrJ/EryC1/StrS aminotransferase family
NLHLMEME_00306 5.3e-302 - - - G - - - polysaccharide deacetylase
NLHLMEME_00307 3.05e-249 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NLHLMEME_00308 0.0 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NLHLMEME_00309 1.44e-51 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal L27 protein
NLHLMEME_00310 1.01e-62 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
NLHLMEME_00311 0.0 rne 3.1.26.12 - J ko:K08300,ko:K08301 ko03018,map03018 ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 Ribonuclease E/G family
NLHLMEME_00312 8.53e-294 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Peptidase dimerisation domain
NLHLMEME_00313 1.58e-213 - - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
NLHLMEME_00314 6.01e-214 - 4.1.2.28 - EM ko:K22397 ko00040,map00040 ko00000,ko00001,ko01000 Dihydrodipicolinate synthetase family
NLHLMEME_00315 1.15e-190 - - - S ko:K07046 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 Amidohydrolase
NLHLMEME_00316 9.13e-269 fucP - - G ko:K02429 - ko00000,ko02000 Major Facilitator Superfamily
NLHLMEME_00317 1.51e-190 - 1.1.1.100, 1.1.1.413 - IQ ko:K00059,ko:K18333,ko:K22322 ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 KR domain
NLHLMEME_00318 0.0 - 4.2.1.68 - M ko:K18334 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 Enolase C-terminal domain-like
NLHLMEME_00319 4.75e-245 - - - K ko:K02529 - ko00000,ko03000 Bacterial regulatory proteins, lacI family
NLHLMEME_00320 0.0 - - - V - - - Efflux ABC transporter, permease protein
NLHLMEME_00321 8.7e-178 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NLHLMEME_00322 3.47e-38 - - - S - - - Protein of unknown function (DUF1778)
NLHLMEME_00323 4.05e-119 - - - K - - - Acetyltransferase (GNAT) family
NLHLMEME_00324 0.0 maf - - DF ko:K06287 - ko00000 Maf-like protein
NLHLMEME_00325 1.25e-261 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NLHLMEME_00326 1.59e-303 hom 1.1.1.3, 2.7.2.4 - E ko:K00003,ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Homoserine dehydrogenase
NLHLMEME_00327 1.44e-65 nagE 2.7.1.193 - G ko:K02802,ko:K02803,ko:K02804 ko00520,ko02060,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
NLHLMEME_00328 3.11e-72 - 2.7.1.208 - G ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NLHLMEME_00329 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NLHLMEME_00330 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
NLHLMEME_00331 4.49e-169 - - - K - - - Bacterial regulatory proteins, tetR family
NLHLMEME_00332 3.15e-279 - - - G - - - Transmembrane secretion effector
NLHLMEME_00333 0.0 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NLHLMEME_00334 0.0 nox - - C - - - Pyridine nucleotide-disulphide oxidoreductase
NLHLMEME_00335 1.98e-280 pyr 1.3.98.1 - F ko:K00226 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Dihydroorotate dehydrogenase
NLHLMEME_00336 3.44e-26 - - - T - - - Histidine kinase
NLHLMEME_00337 2.24e-19 - - - S ko:K08981 - ko00000 Bacterial PH domain
NLHLMEME_00338 6.62e-171 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NLHLMEME_00339 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NLHLMEME_00340 2.37e-181 ltbR - - K - - - Transcriptional regulator, IclR family, C-terminal domain protein
NLHLMEME_00341 0.0 - - - S - - - Calcineurin-like phosphoesterase
NLHLMEME_00342 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NLHLMEME_00343 2.65e-316 mutT 3.6.1.55 - LT ko:K03574 - ko00000,ko01000,ko03400 Phosphoglycerate mutase family
NLHLMEME_00344 6.96e-176 - - - - - - - -
NLHLMEME_00345 0.0 - - - G - - - N-terminal domain of (some) glycogen debranching enzymes
NLHLMEME_00346 8.49e-66 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NLHLMEME_00347 9.47e-151 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NLHLMEME_00348 1.05e-107 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NLHLMEME_00349 1.27e-274 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
NLHLMEME_00350 3.02e-280 gluQ 6.1.1.17 - J ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
NLHLMEME_00352 0.0 clpB - - O ko:K03695,ko:K03696 ko01100,ko04213,map01100,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NLHLMEME_00353 8.1e-209 - - - S ko:K07088 - ko00000 Auxin Efflux Carrier
NLHLMEME_00354 8.13e-200 - - - Q - - - Fumarylacetoacetate (FAA) hydrolase family
NLHLMEME_00355 4.95e-160 - - - S - - - Domain of unknown function (DUF4190)
NLHLMEME_00356 1.22e-220 - - - - - - - -
NLHLMEME_00357 8.06e-298 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
NLHLMEME_00358 9.88e-57 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 sugar phosphate isomerase involved in capsule formation
NLHLMEME_00359 1.41e-72 - - - G - - - Branched-chain amino acid transport system / permease component
NLHLMEME_00360 9.99e-96 - - - P - - - branched-chain amino acid ABC transporter, permease protein
NLHLMEME_00361 1.26e-144 - - - G - - - ATPases associated with a variety of cellular activities
NLHLMEME_00362 3.96e-100 - - - G - - - ABC-type sugar transport system periplasmic component
NLHLMEME_00363 2.23e-210 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the FGGY kinase family
NLHLMEME_00364 1.29e-91 xylR - - GK - - - ROK family
NLHLMEME_00365 3.99e-155 - - - - - - - -
NLHLMEME_00366 1.21e-243 - - - M - - - Glycosyltransferase like family 2
NLHLMEME_00367 4.44e-45 - - - M - - - Psort location CytoplasmicMembrane, score 9.26
NLHLMEME_00368 1.29e-33 - - - M - - - Psort location CytoplasmicMembrane, score 9.26
NLHLMEME_00369 9.6e-77 - - - S - - - Predicted membrane protein (DUF2142)
NLHLMEME_00371 7.2e-174 gpmB 3.1.3.85, 5.4.2.11 - G ko:K01834,ko:K22306 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Phosphoglycerate mutase family
NLHLMEME_00372 5.45e-86 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NLHLMEME_00373 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NLHLMEME_00374 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
NLHLMEME_00375 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
NLHLMEME_00376 0.0 yrhL - - I - - - Psort location CytoplasmicMembrane, score 9.99
NLHLMEME_00377 1.37e-244 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NLHLMEME_00379 0.0 pta 2.3.1.8 - C ko:K13788 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphate acetyltransferase
NLHLMEME_00380 8.03e-296 ackA 2.7.2.1 - H ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NLHLMEME_00381 0.0 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NLHLMEME_00382 1.33e-273 - - - - - - - -
NLHLMEME_00383 1.29e-156 - - - - - - - -
NLHLMEME_00385 1.12e-28 - 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Methyladenine glycosylase
NLHLMEME_00387 1.78e-161 - - - S - - - GyrI-like small molecule binding domain
NLHLMEME_00388 1.23e-116 - - - K - - - Putative zinc ribbon domain
NLHLMEME_00389 9.36e-18 zntR - - K - - - bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
NLHLMEME_00390 0.0 glgX 3.2.1.68 CBM48,GH13 G ko:K01214 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 13 family
NLHLMEME_00391 4.87e-163 - - - L - - - NUDIX domain
NLHLMEME_00392 3.81e-226 - - - L - - - NIF3 (NGG1p interacting factor 3)
NLHLMEME_00393 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NLHLMEME_00394 1.77e-168 pdtaR - - T ko:K22010 - ko00000,ko00002,ko02022 Response regulator receiver domain protein
NLHLMEME_00396 1.12e-142 aspA 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
NLHLMEME_00397 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Pyruvate kinase
NLHLMEME_00398 3.81e-228 terC - - P ko:K05794 - ko00000 Integral membrane protein, TerC family
NLHLMEME_00399 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NLHLMEME_00400 2.16e-148 coaE 2.7.1.24 - H ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NLHLMEME_00401 0.0 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
NLHLMEME_00402 2.64e-210 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NLHLMEME_00403 5.3e-264 - - - P ko:K02077 - ko00000,ko00002,ko02000 Zinc-uptake complex component A periplasmic
NLHLMEME_00404 1.29e-206 - - - P ko:K02074 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NLHLMEME_00405 1.34e-175 znuB - - U ko:K02075 - ko00000,ko00002,ko02000 ABC 3 transport family
NLHLMEME_00406 5.08e-114 ispF 2.7.7.60, 4.6.1.12 - H ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
NLHLMEME_00407 2.16e-130 carD - - K ko:K07736 - ko00000,ko03000 CarD-like/TRCF domain
NLHLMEME_00408 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NLHLMEME_00409 1.23e-164 cseB - - T - - - Response regulator receiver domain protein
NLHLMEME_00410 1.43e-249 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
NLHLMEME_00411 9.12e-159 pyrE_1 - - S - - - Phosphoribosyl transferase domain
NLHLMEME_00412 5.66e-188 - - - T - - - Eukaryotic phosphomannomutase
NLHLMEME_00413 5.02e-100 - - - S - - - Zincin-like metallopeptidase
NLHLMEME_00414 0.0 - - - - - - - -
NLHLMEME_00415 0.0 - - - S - - - Glycosyl transferase, family 2
NLHLMEME_00416 2.06e-74 whiB2 - - K ko:K18955 - ko00000,ko03000 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
NLHLMEME_00417 1.79e-303 lytR2 - - K - - - Cell envelope-related transcriptional attenuator domain
NLHLMEME_00418 0.0 - - - D ko:K03466 - ko00000,ko03036 FtsK/SpoIIIE family
NLHLMEME_00419 8.13e-62 whiB - - K ko:K18955 - ko00000,ko03000 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
NLHLMEME_00420 0.0 pdtaS 2.7.13.3 - T ko:K00936 - ko00000,ko00002,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
NLHLMEME_00421 4.44e-204 hlyIII - - S ko:K11068 - ko00000,ko02042 Haemolysin-III related
NLHLMEME_00422 7.1e-106 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NLHLMEME_00423 8.17e-98 fkbP 5.2.1.8 - G ko:K01802 - ko00000,ko01000 Peptidyl-prolyl cis-trans
NLHLMEME_00424 0.0 sdaA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase alpha chain
NLHLMEME_00425 1.16e-121 - - - - - - - -
NLHLMEME_00427 1.83e-233 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 Ppx/GppA phosphatase family
NLHLMEME_00428 4.79e-134 - - - S ko:K09009 - ko00000 Protein of unknown function (DUF501)
NLHLMEME_00429 4.64e-114 - - - D - - - Septum formation initiator
NLHLMEME_00430 2.49e-313 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NLHLMEME_00431 1.82e-227 - - - C - - - Aldo/keto reductase family
NLHLMEME_00432 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NLHLMEME_00433 3.48e-146 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NLHLMEME_00434 6.7e-121 - 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
NLHLMEME_00435 0.0 - - - S ko:K09118 - ko00000 Uncharacterised protein family (UPF0182)
NLHLMEME_00436 5.24e-29 - 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Glycosyl hydrolase family 3 N-terminal domain protein
NLHLMEME_00437 5.54e-113 - 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Glycosyl hydrolase family 3 N-terminal domain protein
NLHLMEME_00438 1.1e-177 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NLHLMEME_00439 4.41e-125 - - - - - - - -
NLHLMEME_00440 7.77e-299 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NLHLMEME_00441 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase N terminus
NLHLMEME_00442 2.8e-91 - - - S - - - ABC-2 family transporter protein
NLHLMEME_00443 7.88e-155 - - - S - - - ABC-2 family transporter protein
NLHLMEME_00444 4.99e-222 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NLHLMEME_00445 3.32e-76 - - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
NLHLMEME_00446 1.7e-69 - - - J - - - Acetyltransferase (GNAT) domain
NLHLMEME_00447 8.1e-153 - - - S - - - Haloacid dehalogenase-like hydrolase
NLHLMEME_00448 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
NLHLMEME_00449 6.4e-235 nadK 2.7.1.23 - H ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NLHLMEME_00451 9.24e-90 trkA - - P ko:K03499 - ko00000,ko02000 TrkA-N domain
NLHLMEME_00452 1.89e-151 - - - - - - - -
NLHLMEME_00453 8.64e-178 tlyA 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
NLHLMEME_00455 1.33e-254 - - - G - - - Haloacid dehalogenase-like hydrolase
NLHLMEME_00456 7.76e-295 - - - L - - - Tetratricopeptide repeat
NLHLMEME_00457 0.0 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NLHLMEME_00458 2.29e-98 - - - S - - - Protein of unknown function (DUF975)
NLHLMEME_00459 9.39e-181 - - - S - - - Putative ABC-transporter type IV
NLHLMEME_00460 6.92e-133 - - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
NLHLMEME_00461 5.26e-84 - - - P - - - Rhodanese Homology Domain
NLHLMEME_00462 9.78e-190 thiF 2.7.7.73, 2.7.7.80, 2.8.1.11 - H ko:K03148,ko:K21147 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 ThiF family
NLHLMEME_00463 1.19e-200 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
NLHLMEME_00464 5.91e-38 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 ThiS family
NLHLMEME_00465 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
NLHLMEME_00466 1.62e-44 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
NLHLMEME_00467 1.72e-58 - - - S ko:K19158 - ko00000,ko01000,ko02048 YoeB-like toxin of bacterial type II toxin-antitoxin system
NLHLMEME_00468 7.82e-119 - - - L - - - PFAM Integrase catalytic
NLHLMEME_00469 1.2e-303 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
NLHLMEME_00470 1.24e-109 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
NLHLMEME_00471 7.19e-234 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NLHLMEME_00472 1.39e-314 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class-III
NLHLMEME_00473 1.96e-225 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
NLHLMEME_00474 3.37e-272 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NLHLMEME_00475 5.47e-258 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NLHLMEME_00476 5.13e-137 - - - - - - - -
NLHLMEME_00477 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Phenylalanyl-tRNA synthetase beta
NLHLMEME_00478 4.35e-258 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NLHLMEME_00479 8.12e-205 tsnR - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NLHLMEME_00480 9.14e-212 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
NLHLMEME_00481 0.0 ykoD - - P ko:K16785,ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
NLHLMEME_00482 3.75e-141 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
NLHLMEME_00483 0.0 argE - - E - - - Peptidase dimerisation domain
NLHLMEME_00484 4.43e-130 - - - S - - - Protein of unknown function (DUF3043)
NLHLMEME_00485 0.0 lpdA 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NLHLMEME_00486 4.82e-181 - - - S - - - Domain of unknown function (DUF4191)
NLHLMEME_00487 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
NLHLMEME_00488 7.58e-119 - - - L ko:K07497 - ko00000 Integrase core domain
NLHLMEME_00489 1.76e-67 - - - L - - - Helix-turn-helix domain
NLHLMEME_00490 1.9e-258 - - - G - - - Domain of unknown function (DUF4091)
NLHLMEME_00491 6.44e-66 - - - L - - - Transposase, Mutator family
NLHLMEME_00492 2.64e-122 - - - L - - - PFAM Integrase catalytic
NLHLMEME_00494 7.05e-290 - - - L - - - Belongs to the 'phage' integrase family
NLHLMEME_00495 2.26e-246 - - - L - - - Phage integrase family
NLHLMEME_00496 1.75e-256 - - - L ko:K03733 - ko00000,ko03036 Phage integrase, N-terminal SAM-like domain
NLHLMEME_00497 1.95e-124 - - - L - - - HTH-like domain
NLHLMEME_00498 7.09e-108 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
NLHLMEME_00499 1.66e-91 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
NLHLMEME_00500 1.02e-23 - - - L - - - Transposase
NLHLMEME_00502 3.32e-263 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
NLHLMEME_00503 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NLHLMEME_00504 0.0 - - - S - - - Tetratricopeptide repeat
NLHLMEME_00505 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NLHLMEME_00506 3.64e-178 - - - P ko:K16784 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
NLHLMEME_00507 4.73e-285 - - - E - - - Aminotransferase class I and II
NLHLMEME_00508 5.32e-244 - - - P - - - NMT1/THI5 like
NLHLMEME_00509 2.46e-173 - - - P - - - Binding-protein-dependent transport system inner membrane component
NLHLMEME_00510 1.58e-197 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 - H ko:K00806,ko:K14215,ko:K21273 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NLHLMEME_00511 1.13e-164 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
NLHLMEME_00512 0.0 - - - I - - - acetylesterase activity
NLHLMEME_00513 6.58e-294 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NLHLMEME_00514 1.77e-281 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
NLHLMEME_00515 3.93e-301 - - - NU - - - Tfp pilus assembly protein FimV
NLHLMEME_00517 2.42e-96 - - - S - - - Protein of unknown function (DUF3052)
NLHLMEME_00518 2.12e-210 sdrC - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
NLHLMEME_00519 0.0 - - - S - - - Zincin-like metallopeptidase
NLHLMEME_00520 0.0 uvrD2 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
NLHLMEME_00521 0.0 mphA - - S - - - Aminoglycoside phosphotransferase
NLHLMEME_00522 3.25e-44 - - - S - - - Protein of unknown function (DUF3107)
NLHLMEME_00523 1.8e-215 PPA1328 3.1.3.97, 3.1.4.57 - S ko:K07053,ko:K20859 ko00440,map00440 ko00000,ko00001,ko01000 DNA polymerase alpha chain like domain
NLHLMEME_00524 2.39e-166 - - - S - - - Vitamin K epoxide reductase
NLHLMEME_00525 1.87e-218 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
NLHLMEME_00526 4.68e-190 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
NLHLMEME_00527 8.15e-204 - - - S - - - Patatin-like phospholipase
NLHLMEME_00528 3.9e-71 - - - S ko:K07133 - ko00000 Domain of unknown function (DUF4143)
NLHLMEME_00529 1.03e-169 hflK - - O - - - prohibitin homologues
NLHLMEME_00530 1.41e-11 - 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Cys/Met metabolism PLP-dependent enzyme
NLHLMEME_00531 2.13e-222 - - - S ko:K07133 - ko00000 Domain of unknown function (DUF4143)
NLHLMEME_00532 1.32e-56 - - - O - - - Glutaredoxin
NLHLMEME_00533 7.76e-299 metC1 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
NLHLMEME_00534 1.6e-161 - - - S ko:K06999 - ko00000 Phospholipase/Carboxylesterase
NLHLMEME_00535 0.0 tetM - - J ko:K18220 - br01600,ko00000,ko01504 Elongation factor G, domain IV
NLHLMEME_00536 6.18e-06 - - - - - - - -
NLHLMEME_00537 7.2e-175 - 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Exonuclease, DNA polymerase III, epsilon subunit family
NLHLMEME_00538 2.64e-135 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
NLHLMEME_00539 2.65e-217 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
NLHLMEME_00540 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase large chain, oligomerisation domain
NLHLMEME_00541 1.71e-305 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
NLHLMEME_00542 1.24e-121 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NLHLMEME_00543 6.57e-136 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NLHLMEME_00544 1.23e-162 - - - V ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NLHLMEME_00545 2.46e-175 - - - V ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
NLHLMEME_00546 0.0 - - - T - - - Diguanylate cyclase, GGDEF domain
NLHLMEME_00547 0.0 - 3.2.1.14 GH18 S ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Carbohydrate binding domain
NLHLMEME_00548 0.0 - - - M - - - probably involved in cell wall
NLHLMEME_00549 8.21e-202 - - - M - - - probably involved in cell wall
NLHLMEME_00551 7.03e-62 - 4.1.1.44 - L ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
NLHLMEME_00552 1.76e-238 - - - S ko:K07088 - ko00000 Membrane transport protein
NLHLMEME_00553 5.53e-52 - 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
NLHLMEME_00554 3.5e-149 - 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
NLHLMEME_00555 2.12e-05 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
NLHLMEME_00556 2.2e-159 - - - L ko:K07457 - ko00000 endonuclease III
NLHLMEME_00557 2.8e-311 - - - V - - - MatE
NLHLMEME_00558 0.0 uvrA3 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NLHLMEME_00559 1.33e-176 - - - K - - - LysR substrate binding domain
NLHLMEME_00560 1.44e-287 - - - EGP - - - Major Facilitator Superfamily
NLHLMEME_00561 2.56e-197 - - - K - - - LysR substrate binding domain
NLHLMEME_00562 9.67e-274 - - - G - - - N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
NLHLMEME_00564 7.99e-180 - - - K - - - helix_turn _helix lactose operon repressor
NLHLMEME_00565 0.0 - 3.2.1.25 - G ko:K01192 ko00511,ko04142,map00511,map04142 ko00000,ko00001,ko01000 beta-mannosidase
NLHLMEME_00566 2.17e-179 - - - E ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
NLHLMEME_00567 4.19e-173 - - - EP ko:K02031,ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Oligopeptide/dipeptide transporter, C-terminal region
NLHLMEME_00568 3.67e-198 - - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NLHLMEME_00569 2.19e-223 - - - EP ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NLHLMEME_00570 0.0 - - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
NLHLMEME_00571 2.89e-295 bglA 3.2.1.21 - G ko:K05350 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Glycosyl hydrolase family 1
NLHLMEME_00572 9.91e-185 - - - E - - - GDSL-like Lipase/Acylhydrolase family
NLHLMEME_00573 1.46e-212 - 3.1.1.53 - E ko:K05970 - ko00000,ko01000 Carbohydrate esterase, sialic acid-specific acetylesterase
NLHLMEME_00574 9.68e-99 - - - KT - - - Transcriptional regulatory protein, C terminal
NLHLMEME_00575 1.52e-45 - - - - - - - -
NLHLMEME_00576 0.0 - - - S ko:K07133 - ko00000 Domain of unknown function (DUF4143)
NLHLMEME_00577 1.72e-245 adh 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding dehydrogenase
NLHLMEME_00578 2.71e-88 - - - K - - - MerR family regulatory protein
NLHLMEME_00579 7.39e-115 - - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NLHLMEME_00580 3.93e-78 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NLHLMEME_00581 1.57e-41 - - - S - - - Psort location CytoplasmicMembrane, score
NLHLMEME_00582 1.24e-237 - - - S - - - Conserved hypothetical protein 698
NLHLMEME_00583 6.07e-185 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
NLHLMEME_00584 2.99e-164 tmp1 - - S - - - Domain of unknown function (DUF4391)
NLHLMEME_00585 4.1e-293 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NLHLMEME_00586 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NLHLMEME_00587 1.9e-104 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NLHLMEME_00588 5.77e-81 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NLHLMEME_00589 2.76e-247 - - - S ko:K03453 - ko00000 SBF-like CPA transporter family (DUF4137)
NLHLMEME_00591 2.12e-252 ltaE 4.1.2.48 - E ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 Beta-eliminating lyase
NLHLMEME_00592 4.49e-279 - - - M - - - Glycosyl transferase 4-like domain
NLHLMEME_00593 3.65e-291 - 2.6.1.1, 2.6.1.2, 2.6.1.66, 2.6.1.83 - E ko:K00812,ko:K08969,ko:K10206,ko:K14260,ko:K14261 ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
NLHLMEME_00594 1.57e-296 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NLHLMEME_00595 4.83e-176 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
NLHLMEME_00596 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 CobB/CobQ-like glutamine amidotransferase domain
NLHLMEME_00597 4.34e-298 - - - I - - - alpha/beta hydrolase fold
NLHLMEME_00598 0.0 - - - Q - - - D-alanine [D-alanyl carrier protein] ligase activity
NLHLMEME_00599 1.48e-141 - - - Q - - - D-alanine [D-alanyl carrier protein] ligase activity
NLHLMEME_00600 6.85e-132 nnrE - - L - - - Uracil DNA glycosylase superfamily
NLHLMEME_00601 1.95e-19 - - - C - - - Aldo/keto reductase family
NLHLMEME_00602 3.86e-42 - - - - - - - -
NLHLMEME_00603 0.0 - - - L ko:K03502 - ko00000,ko03400 DNA-damage repair protein (DNA polymerase IV) K00961
NLHLMEME_00604 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NLHLMEME_00605 6.44e-240 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
NLHLMEME_00606 2.99e-309 purD 6.3.3.1, 6.3.4.13 - F ko:K01945,ko:K11788 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
NLHLMEME_00607 0.0 aldH 1.2.1.3, 1.2.99.10 - C ko:K00128,ko:K22445 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldehyde dehydrogenase family
NLHLMEME_00608 0.0 - - - M - - - Psort location CytoplasmicMembrane, score 9.26
NLHLMEME_00609 8.45e-210 - - - P ko:K02077 - ko00000,ko00002,ko02000 Zinc-uptake complex component A periplasmic
NLHLMEME_00610 3.75e-126 - - - S - - - cobalamin synthesis protein
NLHLMEME_00611 8.31e-40 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal L28 family
NLHLMEME_00612 5.79e-28 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L33
NLHLMEME_00613 1.02e-57 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NLHLMEME_00614 1.72e-45 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
NLHLMEME_00615 4.34e-21 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L36
NLHLMEME_00616 6.34e-27 - - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Ribosomal L32p protein family
NLHLMEME_00617 1.78e-34 - - - P ko:K02077,ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
NLHLMEME_00618 2.67e-238 - - - S ko:K07089 - ko00000 Predicted permease
NLHLMEME_00619 1.14e-179 - - - S - - - TIGRFAM TIGR03943 family protein
NLHLMEME_00621 5.02e-47 - - - - - - - -
NLHLMEME_00622 1.72e-90 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
NLHLMEME_00623 4.47e-33 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
NLHLMEME_00624 1.19e-97 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
NLHLMEME_00625 7.7e-95 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
NLHLMEME_00626 3.18e-282 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NLHLMEME_00627 6.94e-110 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NLHLMEME_00628 3.27e-230 yogA - - C - - - Zinc-binding dehydrogenase
NLHLMEME_00629 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NLHLMEME_00630 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
NLHLMEME_00631 2.83e-259 - - - M - - - Conserved repeat domain
NLHLMEME_00632 1.27e-181 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NLHLMEME_00633 6.03e-109 msrA 1.8.4.11, 1.8.4.12 - O ko:K12267 - ko00000,ko01000 peptide-methionine (S)-S-oxide reductase activity
NLHLMEME_00634 0.0 dppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
NLHLMEME_00635 2.81e-18 - - - L ko:K07483 - ko00000 Psort location Cytoplasmic, score 8.87
NLHLMEME_00636 1.7e-302 - 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
NLHLMEME_00637 6.26e-34 - - - - - - - -
NLHLMEME_00639 1.36e-93 - - - NT - - - phage tail tape measure protein
NLHLMEME_00640 5.03e-92 - - - S - - - phage tail
NLHLMEME_00641 9.69e-283 - - - S - - - Prophage endopeptidase tail
NLHLMEME_00644 1.99e-46 - - - - - - - -
NLHLMEME_00645 7.61e-160 - - - - - - - -
NLHLMEME_00648 0.000663 - - - - - - - -
NLHLMEME_00649 2.76e-25 - - - - - - - -
NLHLMEME_00650 4.98e-135 - - - M - - - Glycosyl hydrolases family 25
NLHLMEME_00651 1.97e-37 - - - S - - - Putative phage holin Dp-1
NLHLMEME_00652 2.45e-50 - - - - - - - -
NLHLMEME_00653 2.66e-57 - - - S ko:K09803 - ko00000 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system
NLHLMEME_00654 1.71e-128 - - - L - - - Phage integrase family
NLHLMEME_00656 8.61e-264 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NLHLMEME_00657 1.76e-192 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
NLHLMEME_00658 9.96e-40 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NLHLMEME_00659 8.25e-100 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NLHLMEME_00660 1.83e-194 atpH - - C ko:K02109,ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NLHLMEME_00661 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NLHLMEME_00662 5.1e-211 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NLHLMEME_00663 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NLHLMEME_00664 1.04e-64 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
NLHLMEME_00665 8.64e-166 nucS - - L ko:K07503 - ko00000,ko01000 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
NLHLMEME_00666 2.43e-214 - 5.2.1.8 - M ko:K01802 - ko00000,ko01000 FKBP-type peptidyl-prolyl cis-trans isomerase
NLHLMEME_00667 1.24e-241 - - - - - - - -
NLHLMEME_00668 7.72e-231 - - - - - - - -
NLHLMEME_00669 1.26e-219 ybbN - - O ko:K05838 - ko00000,ko03110 Tetratricopeptide repeat
NLHLMEME_00670 9.16e-151 - - - S - - - CYTH
NLHLMEME_00673 2.69e-82 psp1 3.5.99.10 - J ko:K09022 - ko00000,ko01000 Endoribonuclease L-PSP
NLHLMEME_00674 7.25e-241 plsC2 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Phosphate acyltransferases
NLHLMEME_00675 3.39e-229 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
NLHLMEME_00676 5.18e-294 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
NLHLMEME_00677 4.13e-276 - - - P ko:K02055 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
NLHLMEME_00678 3.98e-206 - - - U ko:K02054 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NLHLMEME_00679 2.37e-198 - - - U ko:K02053 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NLHLMEME_00680 1.85e-302 - - - E ko:K02052 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NLHLMEME_00681 3.41e-235 - - - S - - - CAAX protease self-immunity
NLHLMEME_00682 6.51e-176 - - - M - - - Mechanosensitive ion channel
NLHLMEME_00683 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Fumarase C C-terminus
NLHLMEME_00684 1.21e-15 - - - L - - - Transposase DDE domain
NLHLMEME_00685 6.67e-171 - - - S ko:K07090 - ko00000 Sulfite exporter TauE/SafE
NLHLMEME_00686 0.0 - - - C ko:K06871 - ko00000 Iron-sulfur cluster-binding domain
NLHLMEME_00687 5.79e-247 - - - K - - - helix_turn _helix lactose operon repressor
NLHLMEME_00688 0.0 - - - P - - - Domain of unknown function (DUF4976)
NLHLMEME_00689 0.0 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
NLHLMEME_00690 1.85e-211 - - - P ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NLHLMEME_00691 1.14e-227 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NLHLMEME_00692 3.17e-301 - - - S ko:K07133 - ko00000 AAA domain
NLHLMEME_00693 3.58e-50 - - - L - - - Transposase, Mutator family
NLHLMEME_00694 2.01e-136 - - - K - - - Bacterial regulatory proteins, tetR family
NLHLMEME_00695 0.0 - - - S - - - Psort location Cytoplasmic, score 8.87
NLHLMEME_00696 1.04e-110 ogt 2.1.1.63 - L ko:K00567,ko:K07443 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NLHLMEME_00697 2.21e-104 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NLHLMEME_00698 7.31e-87 ams 2.4.1.4 GH13 G ko:K05341 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
NLHLMEME_00701 8.8e-10 - - - - - - - -
NLHLMEME_00702 1.49e-104 - - - - - - - -
NLHLMEME_00703 0.0 - - - M - - - Conserved repeat domain
NLHLMEME_00704 0.0 - - - M - - - LPXTG cell wall anchor motif
NLHLMEME_00706 1.14e-65 - - - - - - - -
NLHLMEME_00707 5.54e-146 - - - - - - - -
NLHLMEME_00708 2.04e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NLHLMEME_00709 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NLHLMEME_00710 3.53e-49 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NLHLMEME_00711 1.35e-87 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NLHLMEME_00712 2.37e-106 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
NLHLMEME_00713 2.57e-118 lemA - - S ko:K03744 - ko00000 LemA family
NLHLMEME_00714 0.0 - - - S - - - Predicted membrane protein (DUF2207)
NLHLMEME_00715 1.47e-13 - - - S - - - Predicted membrane protein (DUF2207)
NLHLMEME_00716 3.16e-295 - - - S - - - Predicted membrane protein (DUF2207)
NLHLMEME_00717 3.36e-27 - - - - - - - -
NLHLMEME_00718 8.24e-216 - - - C - - - Oxidoreductase, aldo keto reductase family protein
NLHLMEME_00719 4.49e-259 - 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Inosine-uridine preferring nucleoside hydrolase
NLHLMEME_00720 8.91e-139 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NLHLMEME_00721 3.56e-47 - - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
NLHLMEME_00722 1.25e-82 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
NLHLMEME_00723 9.26e-278 - - - S - - - Endonuclease/Exonuclease/phosphatase family
NLHLMEME_00724 0.0 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NLHLMEME_00725 3.05e-205 - - - P - - - Cation efflux family
NLHLMEME_00726 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
NLHLMEME_00727 1.06e-175 - 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase C26
NLHLMEME_00728 0.0 yjjK - - S ko:K15738 - ko00000,ko02000 ABC transporter
NLHLMEME_00729 1.75e-92 vapC - - S ko:K07062 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module. An RNase
NLHLMEME_00730 1.52e-57 - - - S ko:K21495 - ko00000,ko02048 Plasmid stability protein
NLHLMEME_00731 8.22e-120 ilvN 2.2.1.6 - E ko:K01653 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 ACT domain
NLHLMEME_00732 0.0 ilvB 2.2.1.6 - H ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Thiamine pyrophosphate enzyme, central domain
NLHLMEME_00733 4.11e-171 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NLHLMEME_00734 4.87e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
NLHLMEME_00735 3.1e-149 - - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
NLHLMEME_00736 1.87e-158 - - - - - - - -
NLHLMEME_00737 9.97e-114 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NLHLMEME_00738 2.31e-66 - - - S - - - Protein of unknown function (DUF3039)
NLHLMEME_00739 9.67e-251 - - - C ko:K19265 - ko00000,ko01000 Aldo/keto reductase family
NLHLMEME_00740 7.41e-102 - - - K - - - MerR, DNA binding
NLHLMEME_00741 1.58e-151 - - - - - - - -
NLHLMEME_00742 4.82e-315 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NLHLMEME_00743 3.84e-186 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NLHLMEME_00744 3.52e-177 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NLHLMEME_00745 4.61e-227 - - - S ko:K07088 - ko00000 Auxin Efflux Carrier
NLHLMEME_00748 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
NLHLMEME_00749 0.0 - - - P ko:K02049 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NLHLMEME_00750 0.0 - - - P ko:K02050 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NLHLMEME_00751 4.28e-78 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NLHLMEME_00752 2.39e-225 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NLHLMEME_00753 5.51e-204 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NLHLMEME_00754 1.37e-270 - - - K - - - helix_turn _helix lactose operon repressor
NLHLMEME_00756 0.0 fadD 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
NLHLMEME_00757 1.28e-48 - - - U ko:K02100 - ko00000,ko02000 Sugar (and other) transporter
NLHLMEME_00758 7.57e-29 - - - U ko:K02100 - ko00000,ko02000 Sugar (and other) transporter
NLHLMEME_00760 0.0 - - - V ko:K06147,ko:K06148,ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter transmembrane region
NLHLMEME_00761 0.0 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
NLHLMEME_00762 2.98e-87 - - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NLHLMEME_00763 0.0 bga1 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
NLHLMEME_00764 1.66e-245 - - - K - - - helix_turn _helix lactose operon repressor
NLHLMEME_00765 0.0 galA 3.2.1.89 - G ko:K01224 - ko00000,ko01000 Glycosyl hydrolase family 53
NLHLMEME_00766 5.13e-211 - - - S - - - Oxidoreductase, aldo keto reductase family protein
NLHLMEME_00767 1.5e-180 - - - L - - - Protein of unknown function (DUF1524)
NLHLMEME_00768 5.52e-301 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
NLHLMEME_00769 0.0 - - - U - - - Drug resistance MFS transporter, drug H antiporter-2 family
NLHLMEME_00770 0.0 - - - H - - - Protein of unknown function (DUF4012)
NLHLMEME_00771 1.28e-290 rfbP - - M - - - Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
NLHLMEME_00772 6.21e-141 etp 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Low molecular weight phosphatase family
NLHLMEME_00773 1.06e-138 - - - S - - - Psort location CytoplasmicMembrane, score 9.99
NLHLMEME_00775 1.92e-238 - - - L - - - Transposase and inactivated derivatives IS30 family
NLHLMEME_00776 1.83e-175 - - - M - - - Psort location Cytoplasmic, score 8.87
NLHLMEME_00777 2.93e-58 - - - M - - - Glycosyltransferase, group 1 family protein
NLHLMEME_00779 9.98e-77 - - - C - - - Polysaccharide pyruvyl transferase
NLHLMEME_00780 3.95e-143 - - - S - - - Psort location CytoplasmicMembrane, score 9.99
NLHLMEME_00781 2.48e-56 XK27_01805 - - M - - - Glycosyltransferase like family 2
NLHLMEME_00782 2.34e-218 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
NLHLMEME_00783 7.23e-60 - - - L - - - Transposase, Mutator family
NLHLMEME_00784 1.25e-13 - - - L - - - HTH-like domain
NLHLMEME_00785 2.78e-27 - - - L - - - PFAM Integrase catalytic
NLHLMEME_00786 2.75e-108 - - - - - - - -
NLHLMEME_00787 1.12e-86 - - - - - - - -
NLHLMEME_00788 3.1e-70 - - - L - - - Transposase, Mutator family
NLHLMEME_00789 2.92e-110 - - - L - - - Transposase, Mutator family
NLHLMEME_00791 0.0 - - - L - - - PFAM Integrase catalytic
NLHLMEME_00792 6.31e-25 - - - S - - - AAA ATPase domain
NLHLMEME_00793 6.93e-127 - - - K - - - Transposase IS116 IS110 IS902
NLHLMEME_00794 3.97e-12 - - - L - - - Transposase and inactivated derivatives IS30 family
NLHLMEME_00795 0.0 - - - S - - - Psort location CytoplasmicMembrane, score 9.99
NLHLMEME_00797 2.88e-91 - - - - - - - -
NLHLMEME_00798 3.15e-312 wcoI - - DM - - - Psort location CytoplasmicMembrane, score
NLHLMEME_00799 2.28e-267 - - - - - - - -
NLHLMEME_00800 2.85e-218 - - - S ko:K21688 - ko00000 G5
NLHLMEME_00801 5.55e-79 trxA 1.8.1.9 - O ko:K00384,ko:K03671 ko00450,ko04621,ko05418,map00450,map04621,map05418 ko00000,ko00001,ko01000,ko03110 Belongs to the thioredoxin family
NLHLMEME_00802 7.47e-156 - - - F - - - Domain of unknown function (DUF4916)
NLHLMEME_00803 4.71e-203 - - - I - - - Alpha/beta hydrolase family
NLHLMEME_00804 1.03e-282 nudC 3.6.1.22 - L ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 ko00000,ko00001,ko01000 NADH pyrophosphatase zinc ribbon domain
NLHLMEME_00805 1.26e-91 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
NLHLMEME_00806 1.35e-282 - - - S - - - Uncharacterized conserved protein (DUF2183)
NLHLMEME_00807 0.0 ptrB 3.4.21.83 - E ko:K01354 ko05142,ko05143,map05142,map05143 ko00000,ko00001,ko01000,ko01002 Peptidase, S9A B C family, catalytic domain protein
NLHLMEME_00808 4.4e-246 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NLHLMEME_00809 5.66e-278 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Biotin/lipoate A/B protein ligase family
NLHLMEME_00810 2.7e-172 crp - - K ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
NLHLMEME_00811 0.0 pon1 - - M - - - Transglycosylase
NLHLMEME_00812 5.77e-304 namA - - C - - - NADH:flavin oxidoreductase / NADH oxidase family
NLHLMEME_00813 1.53e-289 pyrD 1.3.5.2, 1.3.98.1 - F ko:K00226,ko:K00254 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
NLHLMEME_00814 3.61e-158 - - - K - - - DeoR C terminal sensor domain
NLHLMEME_00815 0.0 galT 2.7.7.12 - C ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 Galactose-1-phosphate uridyl transferase, N-terminal domain
NLHLMEME_00816 3.56e-298 galK 2.7.1.6, 2.7.7.12 - G ko:K00849,ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GHMP kinase family. GalK subfamily
NLHLMEME_00817 7.93e-59 - - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
NLHLMEME_00818 0.0 - - - S ko:K09157 - ko00000 UPF0210 protein
NLHLMEME_00819 3.37e-148 spoU 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NLHLMEME_00820 4.18e-237 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 FES
NLHLMEME_00821 1.35e-131 - - - - - - - -
NLHLMEME_00822 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NLHLMEME_00823 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NLHLMEME_00824 0.0 - - - E - - - Transglutaminase-like superfamily
NLHLMEME_00825 5.59e-309 - - - S - - - Protein of unknown function DUF58
NLHLMEME_00826 0.0 - - - S - - - Fibronectin type 3 domain
NLHLMEME_00827 3.42e-281 pknK 2.7.11.1 - KLT ko:K12132 - ko00000,ko01000,ko01001 Protein tyrosine kinase
NLHLMEME_00828 0.0 - - - L - - - PD-(D/E)XK nuclease superfamily
NLHLMEME_00829 0.0 uvrD2 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Belongs to the helicase family. UvrD subfamily
NLHLMEME_00830 9.52e-301 - - - G - - - Major Facilitator Superfamily
NLHLMEME_00831 2.77e-171 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NLHLMEME_00832 4.16e-208 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NLHLMEME_00833 0.0 rnj - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NLHLMEME_00834 0.0 pepN 3.4.11.2 - E ko:K01256,ko:K08776 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Peptidase family M1 domain
NLHLMEME_00835 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NLHLMEME_00836 5.28e-159 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NLHLMEME_00837 0.0 - - - L - - - Psort location Cytoplasmic, score
NLHLMEME_00838 2.52e-263 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NLHLMEME_00839 7.91e-270 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Cell division ATP-binding protein FtsE
NLHLMEME_00840 1.9e-206 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in cellular division
NLHLMEME_00841 2.5e-210 - - - D ko:K21471 - ko00000,ko01000,ko01002,ko01011 CHAP domain protein
NLHLMEME_00842 3.26e-106 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NLHLMEME_00843 1.17e-202 glnH - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter, substrate-binding protein, family 3
NLHLMEME_00844 4.57e-217 glnH - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter, substrate-binding protein, family 3
NLHLMEME_00845 1.54e-222 yecS - - E ko:K02029 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NLHLMEME_00846 3.69e-193 tcyC 3.6.3.21 - E ko:K02028,ko:K02029 - ko00000,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
NLHLMEME_00847 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NLHLMEME_00848 1.77e-180 - 5.4.99.28, 5.4.99.29 - J ko:K06177 - ko00000,ko01000,ko03009,ko03016 RNA pseudouridylate synthase
NLHLMEME_00849 9.16e-240 - - - K - - - Periplasmic binding protein domain
NLHLMEME_00850 1.79e-216 - - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NLHLMEME_00851 1.74e-226 - - - G ko:K02026 - ko00000,ko00002,ko02000 ABC transporter permease
NLHLMEME_00852 0.0 bga1 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
NLHLMEME_00853 0.0 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
NLHLMEME_00854 0.0 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
NLHLMEME_00855 1.29e-183 coaX 2.7.1.33 - H ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NLHLMEME_00856 0.0 - - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
NLHLMEME_00857 1.57e-214 - - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NLHLMEME_00858 4.22e-193 - - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NLHLMEME_00859 6.51e-176 - - - EP ko:K02031 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 oligopeptide transport protein of the ABC superfamily, ATP-binding component
NLHLMEME_00860 1.6e-175 - - - E ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
NLHLMEME_00861 8.21e-245 cbs 2.5.1.47, 4.2.1.22 - E ko:K01697,ko:K01738 ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Pyridoxal-phosphate dependent enzyme
NLHLMEME_00862 3.05e-281 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
NLHLMEME_00863 1.65e-305 - - - G - - - N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
NLHLMEME_00864 0.0 - - - S ko:K09704 - ko00000 Metal-independent alpha-mannosidase (GH125)
NLHLMEME_00865 4.5e-41 - - - - - - - -
NLHLMEME_00866 2.5e-169 - - - C - - - Putative TM nitroreductase
NLHLMEME_00867 6.76e-218 - - - EG - - - EamA-like transporter family
NLHLMEME_00868 2.35e-92 pdxH - - S ko:K07006 - ko00000 Pfam:Pyridox_oxidase
NLHLMEME_00869 2.01e-294 - - - L - - - ribosomal rna small subunit methyltransferase
NLHLMEME_00870 2.1e-215 gpmB 3.1.3.85, 5.4.2.11 - G ko:K01834,ko:K22306 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Phosphoglycerate mutase family
NLHLMEME_00871 4.06e-217 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
NLHLMEME_00872 6.44e-207 - - - ET ko:K10005 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
NLHLMEME_00873 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
NLHLMEME_00874 8.17e-84 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Helix-hairpin-helix motif
NLHLMEME_00875 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein
NLHLMEME_00876 5.05e-221 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
NLHLMEME_00877 2.49e-111 tsaE - - S ko:K06925 - ko00000,ko03016 Threonylcarbamoyl adenosine biosynthesis protein TsaE
NLHLMEME_00878 1.45e-203 yeaZ - - O ko:K14742 - ko00000,ko03016 Glycoprotease family
NLHLMEME_00879 2.84e-136 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 FR47-like protein
NLHLMEME_00880 2.55e-247 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NLHLMEME_00882 5.21e-155 - - - K - - - helix_turn_helix, Lux Regulon
NLHLMEME_00883 9.59e-305 - - - T - - - Histidine kinase
NLHLMEME_00885 3.06e-80 - - - - - - - -
NLHLMEME_00886 2.43e-183 - - - - ko:K20461 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
NLHLMEME_00887 3.6e-181 - - - S ko:K20460 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
NLHLMEME_00888 1.89e-253 - - - V ko:K20459 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
NLHLMEME_00889 2.17e-175 - - - L - - - PFAM Relaxase mobilization nuclease family protein
NLHLMEME_00890 2.03e-179 - - - S - - - Fic/DOC family
NLHLMEME_00892 5.55e-09 - - - K - - - Psort location Cytoplasmic, score
NLHLMEME_00894 2.02e-156 - 2.7.11.1 - S ko:K07154 - ko00000,ko01000,ko01001,ko02048 HipA-like C-terminal domain
NLHLMEME_00895 5.84e-67 - - - L - - - Phage integrase family
NLHLMEME_00897 2.35e-47 - - - M - - - Peptidase family M23
NLHLMEME_00898 0.0 - - - G - - - ABC transporter substrate-binding protein
NLHLMEME_00899 8.16e-308 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the isocitrate and isopropylmalate dehydrogenases family
NLHLMEME_00900 8.81e-264 guaB3 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 IMP dehydrogenase family protein
NLHLMEME_00901 5.83e-120 - - - - - - - -
NLHLMEME_00902 0.0 fadD3 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 long-chain-fatty acid CoA ligase
NLHLMEME_00903 1.96e-113 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NLHLMEME_00904 2.69e-192 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
NLHLMEME_00905 7.92e-187 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NLHLMEME_00906 3.81e-171 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
NLHLMEME_00907 7.06e-120 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NLHLMEME_00908 4.76e-222 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Cytidylyltransferase family
NLHLMEME_00909 6.44e-285 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NLHLMEME_00910 2.78e-92 - 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 DJ-1/PfpI family
NLHLMEME_00911 4.13e-180 hisF 4.1.3.27 - E ko:K01657,ko:K02500 ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NLHLMEME_00912 2.28e-93 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NLHLMEME_00913 0.0 trpE 4.1.3.27 - E ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NLHLMEME_00914 1.21e-82 - - - S ko:K09974 - ko00000 Domain of unknown function (DUF1287)
NLHLMEME_00915 2.77e-226 - - - - - - - -
NLHLMEME_00916 8.67e-101 - - - - - - - -
NLHLMEME_00917 2.87e-81 - - - K - - - Protein of unknown function, DUF488
NLHLMEME_00918 1.52e-10 - - - - - - - -
NLHLMEME_00919 0.0 - - - E ko:K16235 - ko00000,ko02000 amino acid
NLHLMEME_00920 1.89e-94 - - - EGP - - - Major Facilitator Superfamily
NLHLMEME_00921 1.32e-45 hipA 2.7.11.1 - S ko:K07154 - ko00000,ko01000,ko01001,ko02048 kinase activity
NLHLMEME_00922 2.36e-61 - - - K ko:K20391 ko02024,map02024 ko00000,ko00001,ko03000 sequence-specific DNA binding
NLHLMEME_00923 2.58e-139 - - - - - - - -
NLHLMEME_00926 1.39e-155 - - - - - - - -
NLHLMEME_00927 1.5e-65 - - - - - - - -
NLHLMEME_00928 1.1e-129 - - - S - - - Acetyltransferase (GNAT) domain
NLHLMEME_00929 2.41e-82 cefD 5.1.1.17 - E ko:K04127 ko00311,ko01100,ko01130,map00311,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Aminotransferase, class V
NLHLMEME_00930 2.64e-244 - - - V - - - VanZ like family
NLHLMEME_00931 8.59e-117 - - - EGP - - - Major Facilitator Superfamily
NLHLMEME_00932 0.0 - - - E ko:K16235 - ko00000,ko02000 amino acid
NLHLMEME_00933 5.66e-194 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NLHLMEME_00934 4.33e-169 - - - S - - - SOS response associated peptidase (SRAP)
NLHLMEME_00935 0.0 trpB 4.2.1.20 - E ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NLHLMEME_00936 4.72e-207 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NLHLMEME_00937 9.14e-239 lgt - - M - - - Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NLHLMEME_00938 7.16e-155 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribulose-phosphate 3-epimerase
NLHLMEME_00939 5.07e-56 hisE 3.6.1.31 - E ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Phosphoribosyl-ATP pyrophosphohydrolase
NLHLMEME_00940 3.05e-200 hisG 2.4.2.17 - F ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 ATP phosphoribosyltransferase
NLHLMEME_00941 6.65e-138 pgsA2 2.7.8.41, 2.7.8.5 - I ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NLHLMEME_00942 3.46e-218 - - - S - - - Bacterial protein of unknown function (DUF881)
NLHLMEME_00943 6.08e-61 sbp - - S - - - Protein of unknown function (DUF1290)
NLHLMEME_00944 2.65e-180 - - - S - - - Bacterial protein of unknown function (DUF881)
NLHLMEME_00945 2.02e-97 garA - - T - - - Inner membrane component of T3SS, cytoplasmic domain
NLHLMEME_00946 3.85e-144 merR2 - - K - - - helix_turn_helix, mercury resistance
NLHLMEME_00947 3.08e-84 - - - - - - - -
NLHLMEME_00948 4.04e-45 - - - - - - - -
NLHLMEME_00949 2.61e-179 nt5e 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 HAD-hyrolase-like
NLHLMEME_00950 3.18e-81 rbpA - - K - - - Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
NLHLMEME_00951 0.0 helY - - L ko:K03727 - ko00000,ko01000 DEAD DEAH box helicase
NLHLMEME_00952 4.22e-70 - - - - - - - -
NLHLMEME_00953 0.0 - - - K - - - WYL domain
NLHLMEME_00954 0.0 ugp 2.7.7.9 - G ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
NLHLMEME_00955 1.12e-209 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
NLHLMEME_00957 0.0 der - - F ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
NLHLMEME_00958 1.57e-184 rluB 5.4.99.19, 5.4.99.22 - J ko:K06178,ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
NLHLMEME_00959 1.34e-181 - - - U ko:K06188 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NLHLMEME_00960 2.5e-43 - - - - - - - -
NLHLMEME_00961 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
NLHLMEME_00962 1.39e-296 - - - - - - - -
NLHLMEME_00963 3.58e-209 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NLHLMEME_00964 4.18e-282 sucC 6.2.1.5 - F ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
NLHLMEME_00965 1.31e-129 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NLHLMEME_00966 2.53e-71 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit
NLHLMEME_00967 1.5e-254 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NLHLMEME_00968 6.87e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NLHLMEME_00969 4.21e-131 ruvC 3.1.22.4 - L ko:K01159 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NLHLMEME_00970 1.19e-156 yebC - - K - - - transcriptional regulatory protein
NLHLMEME_00971 7.63e-143 - 2.7.7.53 - FG ko:K19710 ko00230,map00230 ko00000,ko00001,ko01000 HIT domain
NLHLMEME_00972 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NLHLMEME_00978 2.48e-171 - - - S - - - PAC2 family
NLHLMEME_00979 1.51e-201 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NLHLMEME_00980 7.54e-200 - - - G - - - Fructosamine kinase
NLHLMEME_00981 1.33e-273 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NLHLMEME_00982 1.41e-244 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NLHLMEME_00983 0.0 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the transketolase family
NLHLMEME_00984 2.71e-259 tal 2.2.1.2 - H ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NLHLMEME_00985 5.53e-306 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
NLHLMEME_00986 8.76e-249 - - - - - - - -
NLHLMEME_00987 0.0 aspC 2.6.1.1, 2.6.1.2, 2.6.1.66 - E ko:K00812,ko:K08969,ko:K14260 ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase, class I II
NLHLMEME_00988 4.04e-205 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
NLHLMEME_00989 7.97e-224 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
NLHLMEME_00990 2.51e-47 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase SecG subunit
NLHLMEME_00991 1.7e-188 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NLHLMEME_00992 1.02e-278 pgk 2.7.2.3, 5.3.1.1 - F ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Phosphoglycerate kinase
NLHLMEME_00993 2.86e-217 whiA - - K ko:K09762 - ko00000 May be required for sporulation
NLHLMEME_00994 1.56e-228 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
NLHLMEME_00995 7.26e-241 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Shikimate dehydrogenase substrate binding domain
NLHLMEME_00996 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NLHLMEME_00997 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NLHLMEME_00998 1.43e-296 - 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Psort location Cytoplasmic, score 8.87
NLHLMEME_00999 1.11e-41 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
NLHLMEME_01000 9.21e-64 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
NLHLMEME_01001 6.73e-76 - - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NLHLMEME_01002 6.87e-72 - - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NLHLMEME_01003 6.37e-169 - - - S - - - Enoyl-(Acyl carrier protein) reductase
NLHLMEME_01004 0.0 ybiT - - S ko:K06158 - ko00000,ko03012 ABC transporter
NLHLMEME_01005 0.0 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NLHLMEME_01006 1.93e-157 - 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
NLHLMEME_01007 1.55e-221 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
NLHLMEME_01008 1.49e-275 - - - S - - - Psort location Cytoplasmic, score 8.87
NLHLMEME_01009 9.25e-39 - - - - - - - -
NLHLMEME_01010 9.36e-160 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NLHLMEME_01011 1.98e-232 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NLHLMEME_01012 7.53e-201 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
NLHLMEME_01013 1.09e-226 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the OMP decarboxylase family. Type 2 subfamily
NLHLMEME_01014 0.0 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NLHLMEME_01015 2.61e-96 pyrI - - F ko:K00610 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002 Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
NLHLMEME_01016 8.93e-229 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
NLHLMEME_01017 0.0 glnE 2.7.7.42, 2.7.7.89 - H ko:K00982 - ko00000,ko01000 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
NLHLMEME_01018 8.46e-240 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NLHLMEME_01019 5.54e-208 metF 1.5.1.20 - E ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Methylenetetrahydrofolate reductase
NLHLMEME_01020 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NLHLMEME_01022 3.95e-127 sixA - - T ko:K08296 - ko00000,ko01000 Phosphoglycerate mutase family
NLHLMEME_01023 6.37e-257 trmI 2.1.1.219, 2.1.1.220 - J ko:K07442 - ko00000,ko01000,ko03016 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
NLHLMEME_01024 8.72e-172 - - - S ko:K06999 - ko00000 Phospholipase/Carboxylesterase
NLHLMEME_01026 5.91e-181 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NLHLMEME_01027 1.99e-187 - - - S - - - phosphoesterase or phosphohydrolase
NLHLMEME_01028 5.53e-117 lppD - - S - - - Appr-1'-p processing enzyme
NLHLMEME_01029 9.74e-227 - - - I - - - alpha/beta hydrolase fold
NLHLMEME_01031 1.29e-164 - - - - - - - -
NLHLMEME_01032 2.64e-165 - - - S - - - Plasmid pRiA4b ORF-3-like protein
NLHLMEME_01033 2.42e-40 rarD - - S ko:K05786 - ko00000,ko02000 EamA-like transporter family
NLHLMEME_01034 1.3e-160 - - - H - - - RibD C-terminal domain
NLHLMEME_01036 7.62e-132 - - - K - - - WYL domain
NLHLMEME_01037 7.51e-196 - 2.7.1.95 - J ko:K19272,ko:K19299 - br01600,ko00000,ko01000,ko01504 Phosphotransferase enzyme family
NLHLMEME_01038 9.78e-130 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
NLHLMEME_01039 3.4e-227 aadK - - H ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
NLHLMEME_01041 1.5e-176 - - - S ko:K09161 - ko00000 YfbU domain
NLHLMEME_01045 3.25e-186 - - - - - - - -
NLHLMEME_01046 1.21e-135 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Redoxin
NLHLMEME_01047 7.27e-207 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
NLHLMEME_01048 2.53e-203 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
NLHLMEME_01049 2.65e-309 glgA 2.4.1.342 GT4 G ko:K16148 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000,ko01003 Starch synthase catalytic domain
NLHLMEME_01050 1.7e-106 - - - - - - - -
NLHLMEME_01051 0.0 - - - S - - - Glycosyl hydrolases related to GH101 family, GH129
NLHLMEME_01052 0.0 dppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
NLHLMEME_01053 0.0 gltD 1.4.1.13, 1.4.1.14 - C ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
NLHLMEME_01054 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase NADPH large subunit
NLHLMEME_01055 1.67e-77 - - - K - - - helix_turn _helix lactose operon repressor
NLHLMEME_01056 1.59e-243 - - - K - - - helix_turn _helix lactose operon repressor
NLHLMEME_01058 8.32e-41 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
NLHLMEME_01059 9.67e-220 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
NLHLMEME_01060 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NLHLMEME_01061 4.75e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
NLHLMEME_01062 4.82e-179 - - - S - - - UPF0126 domain
NLHLMEME_01063 6.23e-189 mazG 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 Psort location Cytoplasmic, score 8.87
NLHLMEME_01064 2.72e-288 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Amino-transferase class IV
NLHLMEME_01065 2.59e-137 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NLHLMEME_01066 2.16e-300 - - - EGP ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
NLHLMEME_01067 7.28e-243 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
NLHLMEME_01068 6.3e-174 ask 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Amino acid kinase family
NLHLMEME_01069 2.87e-126 ask 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 ACT domain
NLHLMEME_01070 1.94e-271 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NLHLMEME_01071 1.64e-143 - - - - - - - -
NLHLMEME_01072 4.09e-219 - - - L - - - Domain of unknown function (DUF4862)
NLHLMEME_01073 6.1e-229 - 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
NLHLMEME_01074 1.2e-162 nanE 5.1.3.9 - G ko:K01788 ko00520,map00520 ko00000,ko00001,ko01000 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
NLHLMEME_01075 2.97e-206 - 3.5.1.106 - I ko:K15357 ko00760,ko01120,map00760,map01120 ko00000,ko00001,ko00002,ko01000 carboxylic ester hydrolase activity
NLHLMEME_01076 0.0 oppA7 - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
NLHLMEME_01077 8.59e-204 oppB6 - - EP ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NLHLMEME_01078 0.0 oppCD2 - - EP ko:K02031,ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Oligopeptide/dipeptide transporter, C-terminal region
NLHLMEME_01079 2.91e-189 oppF - - E ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
NLHLMEME_01080 4.55e-232 nanA 4.1.3.3, 4.3.3.7 - EM ko:K01639,ko:K01714 ko00261,ko00300,ko00520,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map00520,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Dihydrodipicolinate synthetase family
NLHLMEME_01081 3.69e-190 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NLHLMEME_01082 9.97e-18 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Amidohydrolase family
NLHLMEME_01083 0.0 neu 3.2.1.18 GH33 G ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 ko00000,ko00001,ko01000,ko02042 BNR repeat-like domain
NLHLMEME_01084 3.24e-307 - - - P ko:K07133 - ko00000 Domain of unknown function (DUF4143)
NLHLMEME_01085 3.99e-196 - - - K - - - FCD
NLHLMEME_01086 0.0 - - - S - - - Calcineurin-like phosphoesterase
NLHLMEME_01087 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NLHLMEME_01088 0.0 pbp5 - - M - - - Transglycosylase
NLHLMEME_01089 5.51e-212 - - - I - - - PAP2 superfamily
NLHLMEME_01090 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NLHLMEME_01091 4.29e-152 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NLHLMEME_01092 1.31e-265 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
NLHLMEME_01093 1.28e-137 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
NLHLMEME_01094 1.47e-50 hpr - - G ko:K11189 - ko00000,ko02000 PTS HPr component phosphorylation site
NLHLMEME_01096 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NLHLMEME_01097 1.52e-137 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
NLHLMEME_01098 0.0 pepD - - E ko:K08659 - ko00000,ko01000,ko01002 Peptidase family C69
NLHLMEME_01099 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Formate-tetrahydrofolate ligase
NLHLMEME_01100 7.81e-82 - - - S - - - Macrophage migration inhibitory factor (MIF)
NLHLMEME_01101 1.29e-124 - - - S - - - GtrA-like protein
NLHLMEME_01102 0.0 - - - EGP - - - Major Facilitator Superfamily
NLHLMEME_01103 4.52e-161 - - - G - - - Phosphoglycerate mutase family
NLHLMEME_01104 1.73e-205 - - - - - - - -
NLHLMEME_01105 2.09e-288 - 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
NLHLMEME_01106 1.69e-232 - - - S - - - Protein of unknown function (DUF805)
NLHLMEME_01108 0.0 gltX 6.1.1.17 - J ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NLHLMEME_01111 4.58e-82 intA - - L - - - Phage integrase, N-terminal SAM-like domain
NLHLMEME_01113 0.0 - - - P ko:K07243 - ko00000,ko02000 Iron permease FTR1 family
NLHLMEME_01114 1.89e-159 - - - P ko:K07230 - ko00000,ko02000 Fe2+ transport protein
NLHLMEME_01115 1.05e-293 - - - S - - - Predicted membrane protein (DUF2318)
NLHLMEME_01116 1.22e-289 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
NLHLMEME_01117 3.14e-275 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
NLHLMEME_01118 1.39e-187 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NLHLMEME_01119 1.68e-102 - - - S - - - FMN_bind
NLHLMEME_01120 1.62e-130 - - - K - - - Psort location Cytoplasmic, score 8.87
NLHLMEME_01121 0.0 - - - S ko:K01421 - ko00000 YhgE Pip domain protein
NLHLMEME_01122 0.0 - - - S ko:K01421 - ko00000 YhgE Pip domain protein
NLHLMEME_01123 0.0 - - - S - - - Putative ABC-transporter type IV
NLHLMEME_01124 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NLHLMEME_01125 2.39e-191 pgl 3.1.1.31 - G ko:K01057 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
NLHLMEME_01126 1.04e-247 opcA - - G - - - Glucose-6-phosphate dehydrogenase subunit
NLHLMEME_01127 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NLHLMEME_01128 0.0 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
NLHLMEME_01130 0.0 - - - E ko:K08659 - ko00000,ko01000,ko01002 Peptidase family C69
NLHLMEME_01131 2.29e-253 - 2.7.8.12 - M ko:K09809 - ko00000,ko01000 Glycosyltransferase like family 2
NLHLMEME_01132 1.23e-194 icaR - - K - - - Bacterial regulatory proteins, tetR family
NLHLMEME_01133 4.83e-233 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NLHLMEME_01134 1.12e-304 amt - - U ko:K03320 - ko00000,ko02000 Ammonium Transporter Family
NLHLMEME_01135 1.27e-72 glnB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Nitrogen regulatory protein P-II
NLHLMEME_01136 0.0 glnD 2.7.7.59 - O ko:K00990 ko02020,map02020 ko00000,ko00001,ko01000 Nucleotidyltransferase domain
NLHLMEME_01137 8.96e-307 dinF - - V - - - MatE
NLHLMEME_01138 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
NLHLMEME_01139 0.0 murE - - M - - - Domain of unknown function (DUF1727)
NLHLMEME_01140 5.46e-182 cobQ2 - - S ko:K07009 - ko00000 CobB/CobQ-like glutamine amidotransferase domain
NLHLMEME_01141 1.91e-52 - - - S - - - granule-associated protein
NLHLMEME_01142 0.0 - - - S ko:K03688 - ko00000 ABC1 family
NLHLMEME_01143 7.92e-183 - - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NLHLMEME_01144 3.76e-244 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NLHLMEME_01145 6.05e-53 - - - - - - - -
NLHLMEME_01146 1.64e-282 - - - EGP ko:K08217 - br01600,ko00000,ko01504,ko02000 Major facilitator superfamily
NLHLMEME_01147 5.57e-99 - - - D - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NLHLMEME_01148 2.77e-64 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
NLHLMEME_01149 2.88e-109 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
NLHLMEME_01150 2.15e-48 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NLHLMEME_01151 1.72e-94 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
NLHLMEME_01153 2.45e-161 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NLHLMEME_01154 0.0 - 3.6.3.4, 3.6.3.54 - P ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 E1-E2 ATPase
NLHLMEME_01155 9.49e-57 csoR - - S ko:K21600 - ko00000,ko03000 Metal-sensitive transcriptional repressor
NLHLMEME_01156 7.27e-274 rmuC - - S ko:K09760 - ko00000 RmuC family
NLHLMEME_01157 6.9e-142 pyrE1 - - F - - - Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NLHLMEME_01158 2.98e-217 trmH 2.1.1.34 - J ko:K00556 - ko00000,ko01000,ko03016 RNA methyltransferase TrmH family
NLHLMEME_01159 5.76e-215 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NLHLMEME_01160 5.37e-229 - - - - - - - -
NLHLMEME_01161 3.56e-203 - - - K - - - Psort location Cytoplasmic, score
NLHLMEME_01163 1.05e-63 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NLHLMEME_01164 0.0 gatA 6.3.5.6, 6.3.5.7 - F ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NLHLMEME_01165 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NLHLMEME_01166 2.37e-248 - - - J - - - Acetyltransferase (GNAT) domain
NLHLMEME_01167 2.66e-68 - - - S - - - Protein of unknown function (DUF2469)
NLHLMEME_01168 0.0 - - - H - - - Flavin containing amine oxidoreductase
NLHLMEME_01169 0.0 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NLHLMEME_01171 1.41e-31 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 Amino-transferase class IV
NLHLMEME_01172 5.91e-180 - - - L ko:K07485 - ko00000 Transposase
NLHLMEME_01173 1.25e-44 - - - K - - - AraC-like ligand binding domain
NLHLMEME_01174 2.65e-192 araN - - G ko:K10188 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
NLHLMEME_01175 5.07e-159 - - - P ko:K10189,ko:K10241 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NLHLMEME_01176 7.65e-146 araQ - - U ko:K02026,ko:K10190,ko:K10242 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NLHLMEME_01177 8.06e-156 rafA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
NLHLMEME_01178 1.89e-82 tyrA 5.4.99.5 - E ko:K04092 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Chorismate mutase type II
NLHLMEME_01179 0.0 - - - S - - - domain protein
NLHLMEME_01180 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NLHLMEME_01181 0.0 - - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
NLHLMEME_01182 4.17e-163 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NLHLMEME_01183 2.67e-179 glnR - - KT - - - Transcriptional regulatory protein, C terminal
NLHLMEME_01184 4.23e-153 - - - - - - - -
NLHLMEME_01185 2.74e-126 mntP - - P - - - Probably functions as a manganese efflux pump
NLHLMEME_01186 7.94e-119 ppa 3.6.1.1 - C ko:K01507 ko00190,map00190 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NLHLMEME_01187 0.0 glgE 2.4.99.16 GH13 G ko:K16147 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
NLHLMEME_01188 0.0 - - - K - - - RNA polymerase II activating transcription factor binding
NLHLMEME_01189 3.8e-121 - - - L - - - Phage integrase family
NLHLMEME_01193 6.28e-33 - - - - - - - -
NLHLMEME_01194 6.12e-97 - - - V - - - N-acetylmuramoyl-L-alanine amidase
NLHLMEME_01195 1.63e-12 - - - - - - - -
NLHLMEME_01198 1.47e-130 - - - - - - - -
NLHLMEME_01199 1.13e-296 - - - NT - - - phage tail tape measure protein
NLHLMEME_01200 1.17e-25 - - - - - - - -
NLHLMEME_01201 5.21e-70 - - - - - - - -
NLHLMEME_01202 9.79e-77 - - - - - - - -
NLHLMEME_01203 7.89e-26 - - - - - - - -
NLHLMEME_01204 1.52e-18 - - - - - - - -
NLHLMEME_01206 6.09e-162 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
NLHLMEME_01207 4.16e-114 - - - S - - - Phage portal protein
NLHLMEME_01208 1.7e-150 - - - S - - - Terminase
NLHLMEME_01209 2.47e-21 - - - - - - - -
NLHLMEME_01210 7.81e-07 - - - L - - - HNH nucleases
NLHLMEME_01211 1.3e-35 - - - - - - - -
NLHLMEME_01217 1.01e-25 - - - K - - - BetR domain
NLHLMEME_01220 4.5e-09 - - - K - - - sequence-specific DNA binding
NLHLMEME_01224 1.31e-23 - - - O - - - COG0330 Membrane protease subunits, stomatin prohibitin homologs
NLHLMEME_01229 1.65e-67 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
NLHLMEME_01233 3.51e-45 - - - V - - - HNH endonuclease
NLHLMEME_01234 1.81e-53 - - - A ko:K13288 ko03008,map03008 ko00000,ko00001,ko01000,ko03009,ko03019 3'-to-5' exoribonuclease specific for small oligoribonucleotides
NLHLMEME_01235 1.43e-52 - - - S - - - Protein of unknwon function (DUF3310)
NLHLMEME_01242 8.55e-11 whiB - - K ko:K18955 - ko00000,ko03000 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
NLHLMEME_01247 2.49e-46 - - - L - - - HNH endonuclease
NLHLMEME_01248 2.07e-11 - - - - - - - -
NLHLMEME_01249 1.34e-301 - - - S - - - Terminase
NLHLMEME_01250 3.18e-220 - - - S - - - Phage portal protein, SPP1 Gp6-like
NLHLMEME_01251 2.64e-110 - - - - - - - -
NLHLMEME_01253 1.28e-171 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NLHLMEME_01254 0.0 hgdC - - I - - - CoA enzyme activase uncharacterised domain (DUF2229)
NLHLMEME_01255 0.0 egtA 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Glutamate-cysteine ligase family 2(GCS2)
NLHLMEME_01256 4.33e-180 - - - K - - - Bacterial regulatory proteins, tetR family
NLHLMEME_01257 0.0 bgl2 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Fibronectin type III-like domain
NLHLMEME_01259 7.12e-62 - - - S - - - Nucleotidyltransferase domain
NLHLMEME_01260 3.1e-92 - - - S - - - Nucleotidyltransferase substrate binding protein like
NLHLMEME_01261 3.99e-301 - 3.2.1.4, 3.2.1.58 GH5,GH9 G ko:K01179,ko:K01210 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 5 (cellulase A) family
NLHLMEME_01262 2.91e-233 bglB 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Glycosyl hydrolase family 3 N-terminal domain protein
NLHLMEME_01263 5.02e-117 - - - K - - - MarR family
NLHLMEME_01264 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
NLHLMEME_01265 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
NLHLMEME_01266 6.13e-160 rbsR - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
NLHLMEME_01267 1.58e-56 - - - K - - - acetyltransferase
NLHLMEME_01268 1.99e-131 rihA - - F ko:K01250,ko:K12700 - ko00000,ko01000 Inosine-uridine preferring nucleoside hydrolase
NLHLMEME_01269 4.01e-201 - - - C ko:K03326 - ko00000,ko02000 C4-dicarboxylate anaerobic carrier
NLHLMEME_01270 9.93e-210 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NLHLMEME_01271 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NLHLMEME_01272 1.99e-260 - - - P ko:K02055 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
NLHLMEME_01273 5.64e-200 - - - U ko:K02054 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NLHLMEME_01274 2.92e-206 - - - U ko:K02053 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NLHLMEME_01275 2.94e-261 - - - E ko:K02052 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NLHLMEME_01276 8.48e-203 - - - I - - - type I phosphodiesterase nucleotide pyrophosphatase
NLHLMEME_01277 0.0 - 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
NLHLMEME_01278 3.16e-306 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 HsdM N-terminal domain
NLHLMEME_01279 1.71e-52 - 3.1.21.3 - L ko:K01154 - ko00000,ko01000,ko02048 PFAM restriction modification system DNA specificity domain
NLHLMEME_01280 3.82e-66 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 COG0732 Restriction endonuclease S subunits
NLHLMEME_01281 5.98e-134 - - - L - - - Belongs to the 'phage' integrase family
NLHLMEME_01282 1.07e-39 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
NLHLMEME_01283 9.26e-289 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NLHLMEME_01284 5.45e-61 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NLHLMEME_01285 0.0 ilvD 4.2.1.9 - H ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the IlvD Edd family
NLHLMEME_01286 2.33e-238 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NLHLMEME_01287 8.38e-169 - 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
NLHLMEME_01288 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NLHLMEME_01289 8.27e-154 serB 3.1.3.3 - E ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01009 haloacid dehalogenase-like hydrolase
NLHLMEME_01290 8.35e-163 - - - S - - - SNARE associated Golgi protein
NLHLMEME_01291 0.0 arc - - O ko:K13527 ko03050,map03050 ko00000,ko00001,ko00002,ko03051 AAA ATPase forming ring-shaped complexes
NLHLMEME_01292 5.92e-175 - 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
NLHLMEME_01293 0.0 - - - K ko:K02538,ko:K03483,ko:K03491 - ko00000,ko03000 PRD domain
NLHLMEME_01294 1.33e-95 - - - H - - - Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NLHLMEME_01295 4.66e-105 - 2.7.1.202 - G ko:K02768 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NLHLMEME_01296 2.2e-62 - 2.7.1.202 - G ko:K02769 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NLHLMEME_01297 4.16e-229 - - - G ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 Phosphotransferase System
NLHLMEME_01298 1.06e-173 - - - G ko:K17195 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 Ribulose-phosphate 3 epimerase family
NLHLMEME_01299 0.0 dop 3.5.1.119 - S ko:K20814 - ko00000,ko01000,ko03051 Pup-ligase protein
NLHLMEME_01300 4.8e-224 - 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase family
NLHLMEME_01301 8.43e-16 pup - - S ko:K13570 - ko00000,ko04121 Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
NLHLMEME_01302 0.0 pafA 6.3.1.19 - O ko:K13571 - ko00000,ko00002,ko01000,ko03051 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
NLHLMEME_01303 3.31e-57 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Belongs to the bacterial histone-like protein family
NLHLMEME_01304 0.0 - - - S - - - Lysylphosphatidylglycerol synthase TM region
NLHLMEME_01305 0.0 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Adenylosuccinate lyase C-terminal
NLHLMEME_01306 5.85e-141 - - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
NLHLMEME_01307 0.0 - - - S - - - PGAP1-like protein
NLHLMEME_01308 8.64e-76 - - - - - - - -
NLHLMEME_01309 1.48e-213 - - - S ko:K07114 - ko00000,ko02000 von Willebrand factor (vWF) type A domain
NLHLMEME_01310 1.58e-241 - - - S ko:K07114 - ko00000,ko02000 von Willebrand factor (vWF) type A domain
NLHLMEME_01311 1.88e-118 - - - - - - - -
NLHLMEME_01312 4.64e-209 - - - S - - - Protein of unknown function DUF58
NLHLMEME_01313 9.23e-247 moxR - - S ko:K03924 - ko00000,ko01000 ATPase family associated with various cellular activities (AAA)
NLHLMEME_01314 1.4e-169 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NLHLMEME_01315 5.97e-120 - - - S - - - LytR cell envelope-related transcriptional attenuator
NLHLMEME_01316 1.54e-51 cspA - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
NLHLMEME_01317 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NLHLMEME_01318 6.57e-54 - - - S - - - Proteins of 100 residues with WXG
NLHLMEME_01319 3.1e-147 - - - - - - - -
NLHLMEME_01320 1.23e-170 phoP - - KT ko:K02483 - ko00000,ko02022 Response regulator receiver domain protein
NLHLMEME_01321 0.0 phoR 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
NLHLMEME_01322 1.75e-87 cspB - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
NLHLMEME_01323 4.74e-244 - - - S - - - Protein of unknown function (DUF3027)
NLHLMEME_01324 3.99e-231 uspA - - T - - - Belongs to the universal stress protein A family
NLHLMEME_01325 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 ATPase family associated with various cellular activities (AAA)
NLHLMEME_01326 2.92e-15 - - - K - - - AraC-like ligand binding domain
NLHLMEME_01327 2.31e-177 gtr - - U ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Sugar (and other) transporter
NLHLMEME_01328 2.35e-67 - - - I - - - Hydrolase, alpha beta domain protein
NLHLMEME_01329 0.0 - 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 5'-nucleotidase, C-terminal domain
NLHLMEME_01330 4.16e-314 - - - S - - - Domain of Unknown Function (DUF349)
NLHLMEME_01331 0.0 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Histidyl-tRNA synthetase
NLHLMEME_01332 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NLHLMEME_01333 4.29e-130 - - - S - - - Aminoacyl-tRNA editing domain
NLHLMEME_01334 2.71e-197 gluA - - E ko:K10008 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding protein of ABC transporter for glutamate K02028
NLHLMEME_01335 3.16e-189 gluB - - ET ko:K10005 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
NLHLMEME_01336 8.52e-144 gluC - - E ko:K10006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NLHLMEME_01337 5.19e-252 gluD - - E ko:K10007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NLHLMEME_01338 0.0 - - - I - - - PAP2 superfamily
NLHLMEME_01339 9.32e-145 - - - S ko:K06895 - ko00000,ko02000 LysE type translocator
NLHLMEME_01340 0.0 - - - EK ko:K05825,ko:K18907 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko00002,ko01000,ko01504,ko03000 Alanine-glyoxylate amino-transferase
NLHLMEME_01342 1.72e-253 - - - S - - - Polyphosphate kinase 2 (PPK2)
NLHLMEME_01343 0.0 - - - L - - - DEAD DEAH box helicase
NLHLMEME_01344 0.0 rarA - - L ko:K07478 - ko00000 Recombination factor protein RarA
NLHLMEME_01345 1.89e-13 mtrA - - KT ko:K07670 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
NLHLMEME_01346 1.1e-40 mtrB 2.7.13.3 - T ko:K07636,ko:K07654 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
NLHLMEME_01347 0.0 - - - EGP - - - Major Facilitator Superfamily
NLHLMEME_01348 6.69e-238 - - - EH - - - D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
NLHLMEME_01349 1.31e-66 - - - - - - - -
NLHLMEME_01350 7.05e-72 - - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
NLHLMEME_01351 4.67e-63 - - - J ko:K07574 - ko00000,ko03009 CRS1_YhbY
NLHLMEME_01352 0.0 - - - GP ko:K16785,ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NLHLMEME_01353 4.04e-134 - - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NLHLMEME_01354 8.96e-252 - - - S - - - Glycosyltransferase, group 2 family protein
NLHLMEME_01355 3.43e-188 - - - C - - - Putative TM nitroreductase
NLHLMEME_01356 6.61e-181 ppgK 2.7.1.2, 2.7.1.63 - GK ko:K00845,ko:K00886 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
NLHLMEME_01357 0.0 fosC 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
NLHLMEME_01358 1.8e-306 lacY - - P ko:K02532 - ko00000,ko02000 LacY proton/sugar symporter
NLHLMEME_01359 8.6e-250 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
NLHLMEME_01360 0.0 - - - O ko:K13963 ko05146,map05146 ko00000,ko00001 SERine Proteinase INhibitors
NLHLMEME_01361 8.19e-244 - - - - - - - -
NLHLMEME_01362 5.01e-159 - - - K - - - helix_turn_helix, Lux Regulon
NLHLMEME_01363 1.86e-293 - - - T - - - Histidine kinase
NLHLMEME_01364 0.0 - - - G ko:K08369 - ko00000,ko02000 Sugar (and other) transporter
NLHLMEME_01365 1.64e-81 - - - S - - - Thiamine-binding protein
NLHLMEME_01366 6.39e-189 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
NLHLMEME_01367 7.94e-290 - - - O ko:K13525 ko04141,ko05134,map04141,map05134 ko00000,ko00001,ko00002,ko03019,ko04131,ko04147 AAA domain (Cdc48 subfamily)
NLHLMEME_01368 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NLHLMEME_01369 1.73e-201 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NLHLMEME_01370 0.0 glyQS 6.1.1.14 - J ko:K01880 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of glycine to tRNA(Gly)
NLHLMEME_01371 0.0 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NLHLMEME_01372 8.65e-275 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NLHLMEME_01373 2.98e-93 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NLHLMEME_01374 3.44e-60 - - - S ko:K02221 - ko00000,ko02044 YGGT family
NLHLMEME_01375 1.2e-89 - - - V - - - DivIVA protein
NLHLMEME_01376 1.72e-116 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NLHLMEME_01377 4.29e-227 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
NLHLMEME_01378 1.23e-255 - - - K - - - WYL domain
NLHLMEME_01379 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III alpha subunit
NLHLMEME_01381 3.77e-215 dkgV - - C - - - Aldo/keto reductase family
NLHLMEME_01382 0.0 - 4.2.1.53 - S ko:K10254 - ko00000,ko01000 MCRA family
NLHLMEME_01383 4.96e-97 - - - - - - - -
NLHLMEME_01384 3.08e-239 pheA 4.2.1.51, 5.4.99.5 - E ko:K04518,ko:K14170 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
NLHLMEME_01385 2.35e-243 tyrA 1.3.1.12 - E ko:K00210,ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydrogenase
NLHLMEME_01386 2.36e-56 - - - - - - - -
NLHLMEME_01387 0.0 - - - MV ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
NLHLMEME_01388 1.06e-189 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NLHLMEME_01389 1.47e-242 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
NLHLMEME_01390 0.0 dppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
NLHLMEME_01391 1.39e-204 dppB - - EP ko:K02033,ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NLHLMEME_01392 2.81e-233 dppC - - EP ko:K02034,ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 N-terminal TM domain of oligopeptide transport permease C
NLHLMEME_01393 0.0 - - - EP ko:K02031,ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Oligopeptide/dipeptide transporter, C-terminal region
NLHLMEME_01394 1.32e-216 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease/Exonuclease/phosphatase family
NLHLMEME_01395 3.56e-198 - - - S - - - Protein of unknown function (DUF3710)
NLHLMEME_01396 2.99e-174 - - - S - - - Protein of unknown function (DUF3159)
NLHLMEME_01397 1.86e-306 rumA 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NLHLMEME_01398 1.84e-125 - - - - - - - -
NLHLMEME_01399 0.0 ctpE - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
NLHLMEME_01400 5.25e-199 ctpE - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
NLHLMEME_01401 0.0 acnA 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NLHLMEME_01402 1.11e-153 - - - E - - - Psort location Cytoplasmic, score 8.87
NLHLMEME_01403 3.91e-107 - - - K - - - helix_turn_helix, Lux Regulon
NLHLMEME_01404 4.69e-174 - - - S ko:K06890 - ko00000 Belongs to the BI1 family
NLHLMEME_01405 6.96e-213 - - - EG - - - EamA-like transporter family
NLHLMEME_01406 1.99e-192 ywaC 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 Region found in RelA / SpoT proteins
NLHLMEME_01407 0.0 miaB 2.8.4.3 - H ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NLHLMEME_01408 7.74e-232 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NLHLMEME_01409 9.15e-192 fic - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
NLHLMEME_01410 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 FtsK SpoIIIE family protein
NLHLMEME_01411 1.04e-152 pgsA 2.7.8.41, 2.7.8.5 - I ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NLHLMEME_01412 7.34e-123 cinA 3.5.1.42 - S ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
NLHLMEME_01413 1.55e-99 - - - K - - - Helix-turn-helix XRE-family like proteins
NLHLMEME_01414 9.3e-42 - - - S - - - Protein of unknown function (DUF3046)
NLHLMEME_01415 1.25e-263 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NLHLMEME_01416 7.82e-134 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
NLHLMEME_01417 1.24e-154 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NLHLMEME_01418 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NLHLMEME_01419 8.85e-244 trpD 2.4.2.18 - F ko:K00766 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NLHLMEME_01420 1.33e-158 - - - - - - - -
NLHLMEME_01421 1.23e-164 plsC2 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Phosphate acyltransferases
NLHLMEME_01422 0.0 pknL 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 PASTA
NLHLMEME_01423 4.11e-252 idsA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13787 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NLHLMEME_01424 2.92e-147 - - - - - - - -
NLHLMEME_01425 1.24e-248 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NLHLMEME_01426 0.0 gyrB2 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 DNA topoisomerase (ATP-hydrolyzing)
NLHLMEME_01427 2.17e-285 - - - G - - - Major Facilitator Superfamily
NLHLMEME_01428 7.03e-220 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NLHLMEME_01429 0.0 lhr - - L ko:K03724 - ko00000,ko01000,ko03400 DEAD DEAH box helicase
NLHLMEME_01432 2.17e-28 - - - K - - - helix_turn_helix, arabinose operon control protein
NLHLMEME_01433 8.31e-135 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
NLHLMEME_01435 0.0 gyrA2 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 DNA topoisomerase (ATP-hydrolyzing)
NLHLMEME_01436 7.49e-297 - - - S - - - Type I phosphodiesterase / nucleotide pyrophosphatase
NLHLMEME_01437 6.14e-212 - - - S - - - Protein of unknown function (DUF3071)
NLHLMEME_01438 4.95e-63 - - - S - - - Domain of unknown function (DUF4193)
NLHLMEME_01439 5.02e-110 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
NLHLMEME_01440 0.0 relA 2.7.6.5, 3.1.7.2 - KT ko:K00951,ko:K01139 ko00230,map00230 ko00000,ko00001,ko01000,ko03009 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NLHLMEME_01441 2.13e-149 ppiA 5.2.1.8 - G ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 ko00000,ko00001,ko01000,ko03110,ko04147 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NLHLMEME_01442 0.000744 - - - K - - - Helix-turn-helix XRE-family like proteins
NLHLMEME_01443 2.45e-86 - - - - - - - -
NLHLMEME_01445 2.25e-37 - - - - - - - -
NLHLMEME_01446 5.31e-22 - - - - - - - -
NLHLMEME_01447 1.51e-142 - - - S - - - Helix-turn-helix domain
NLHLMEME_01448 2.34e-55 - - - S - - - Helix-turn-helix domain
NLHLMEME_01449 1.84e-55 - - - - - - - -
NLHLMEME_01450 2.36e-116 - - - S - - - Transcription factor WhiB
NLHLMEME_01451 1.22e-146 - - - D ko:K03496 - ko00000,ko03036,ko04812 AAA domain
NLHLMEME_01452 2.5e-40 - - - - - - - -
NLHLMEME_01454 1.43e-51 - - - - ko:K03646 - ko00000,ko02000 -
NLHLMEME_01455 0.0 - - - D - - - Cell surface antigen C-terminus
NLHLMEME_01456 5.33e-36 - - - - - - - -
NLHLMEME_01457 1.95e-186 - - - - - - - -
NLHLMEME_01458 5.06e-83 - - - S - - - PrgI family protein
NLHLMEME_01459 0.0 - - - U - - - type IV secretory pathway VirB4
NLHLMEME_01460 0.0 - - - M - - - CHAP domain
NLHLMEME_01461 1.69e-125 - - - - - - - -
NLHLMEME_01462 2.95e-185 - - - - ko:K03646 - ko00000,ko02000 -
NLHLMEME_01463 6.99e-122 - - - K - - - DNA binding
NLHLMEME_01464 2.19e-128 - 2.1.1.72 - L ko:K06223 ko03430,map03430 ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 D12 class N6 adenine-specific DNA methyltransferase
NLHLMEME_01466 0.0 - - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 Type IV secretory system Conjugative DNA transfer
NLHLMEME_01467 2.16e-68 - - - - - - - -
NLHLMEME_01468 1.06e-68 - - - - - - - -
NLHLMEME_01470 4.21e-185 - - - S - - - Protein of unknown function (DUF3801)
NLHLMEME_01471 0.0 - - - U - - - Relaxase/Mobilisation nuclease domain
NLHLMEME_01472 2.61e-83 - - - S - - - Bacterial mobilisation protein (MobC)
NLHLMEME_01473 2.05e-55 - - - K - - - Protein of unknown function (DUF2442)
NLHLMEME_01474 1.84e-59 - - - S - - - Domain of unknown function (DUF4160)
NLHLMEME_01477 2.16e-83 - - - - - - - -
NLHLMEME_01478 0.0 - 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 DNA topoisomerase
NLHLMEME_01481 1.66e-84 - - - - - - - -
NLHLMEME_01482 2.22e-78 - - - - - - - -
NLHLMEME_01483 1.11e-68 - - - - - - - -
NLHLMEME_01484 6.23e-35 - - - - - - - -
NLHLMEME_01485 1.15e-183 fic - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
NLHLMEME_01486 0.0 intA - - L - - - Phage integrase family
NLHLMEME_01487 4.22e-95 - - - - - - - -
NLHLMEME_01489 0.0 - - - S - - - HipA-like C-terminal domain
NLHLMEME_01490 9.93e-220 - - - S - - - Fic/DOC family
NLHLMEME_01491 2.79e-53 - - - - - - - -
NLHLMEME_01492 0.0 - 3.2.1.24 GH38 G ko:K01191 ko00511,map00511 ko00000,ko00001,ko01000,ko04131 Alpha mannosidase, middle domain
NLHLMEME_01493 0.0 - 3.2.1.24 GH38 G ko:K01191 ko00511,map00511 ko00000,ko00001,ko01000,ko04131 Alpha mannosidase, middle domain
NLHLMEME_01494 5.09e-223 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
NLHLMEME_01495 5.02e-155 - - - G ko:K02025,ko:K17330 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NLHLMEME_01496 2.82e-160 - - - G ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NLHLMEME_01497 1.14e-278 - - - G - - - Belongs to the glycosyl hydrolase 5 (cellulase A) family
NLHLMEME_01498 2.4e-174 - - - K - - - helix_turn _helix lactose operon repressor
NLHLMEME_01500 2.02e-166 - - - S - - - Amidohydrolase
NLHLMEME_01501 2.45e-213 - 4.1.2.28 - EM ko:K22397 ko00040,map00040 ko00000,ko00001,ko01000 Dihydrodipicolinate synthetase family
NLHLMEME_01502 0.0 - 3.2.1.51 GH95 G ko:K15923 ko00511,map00511 ko00000,ko00001,ko01000 Glycosyl hydrolase family 65, N-terminal domain
NLHLMEME_01503 1.58e-198 - - - S - - - Aldo/keto reductase family
NLHLMEME_01504 1.7e-70 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Acylphosphatase
NLHLMEME_01505 0.0 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NLHLMEME_01506 1.57e-279 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NLHLMEME_01507 4.75e-144 hisB 3.1.3.15, 4.2.1.19 - E ko:K01089,ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Imidazoleglycerol-phosphate dehydratase
NLHLMEME_01508 2.17e-162 - - - - - - - -
NLHLMEME_01509 4.88e-154 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NLHLMEME_01510 1.38e-166 hisA 5.3.1.16, 5.3.1.24 - E ko:K01814,ko:K01817 ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Histidine biosynthesis protein
NLHLMEME_01511 0.0 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2252)
NLHLMEME_01512 0.0 glnA2 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
NLHLMEME_01513 1.24e-279 - - - EGP ko:K18567,ko:K19577 - ko00000,ko02000 Major Facilitator Superfamily
NLHLMEME_01514 0.0 hrpA 3.6.4.13 - L ko:K03578 - ko00000,ko01000 Helicase associated domain (HA2) Add an annotation
NLHLMEME_01515 9.47e-158 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase (PrmA)
NLHLMEME_01516 0.0 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NLHLMEME_01517 1.61e-225 ldh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
NLHLMEME_01518 1.33e-205 czcD - - P ko:K16264 - ko00000,ko02000 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NLHLMEME_01519 2.49e-167 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NLHLMEME_01520 7.41e-70 - - - M - - - Lysin motif
NLHLMEME_01521 4.08e-101 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NLHLMEME_01522 4.79e-292 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
NLHLMEME_01523 0.0 - - - L - - - DNA helicase
NLHLMEME_01524 2.33e-120 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
NLHLMEME_01525 2e-241 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NLHLMEME_01526 2.23e-91 - - - D - - - Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NLHLMEME_01527 0.0 ftsI 3.4.16.4 - M ko:K03587 ko00550,ko01501,map00550,map01501 ko00000,ko00001,ko01000,ko01011,ko03036 Penicillin-binding protein, transpeptidase domain protein
NLHLMEME_01528 2.6e-200 - - - M - - - Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NLHLMEME_01529 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NLHLMEME_01530 3.33e-265 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NLHLMEME_01531 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NLHLMEME_01532 2.45e-288 ftsW 2.4.1.227 GT28 D ko:K02563,ko:K03588 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011,ko02000,ko03036 Belongs to the SEDS family
NLHLMEME_01533 3.4e-276 murG 2.4.1.227, 6.3.2.8 GT28 M ko:K01924,ko:K02563 ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NLHLMEME_01534 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
NLHLMEME_01535 8.3e-231 ftsQ - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein FtsQ
NLHLMEME_01537 5e-111 - - - - - - - -
NLHLMEME_01538 2.43e-32 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NLHLMEME_01540 2.8e-61 - - - - - - - -
NLHLMEME_01545 1.12e-13 - - - - - - - -
NLHLMEME_01547 1.95e-63 - - - Q - - - methyltransferase
NLHLMEME_01550 3.46e-15 - - - K ko:K07741 - ko00000 BRO family, N-terminal domain
NLHLMEME_01551 5.23e-05 - - - S - - - Helix-turn-helix domain
NLHLMEME_01554 2.7e-101 - - - L - - - YqaJ-like viral recombinase domain
NLHLMEME_01555 1.47e-75 - - - L ko:K07455 - ko00000,ko03400 RecT family
NLHLMEME_01556 1.51e-65 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-strand binding protein family
NLHLMEME_01557 2.89e-82 - - - - - - - -
NLHLMEME_01558 2.93e-17 - - - - - - - -
NLHLMEME_01560 2.71e-34 - - - - - - - -
NLHLMEME_01562 2.17e-10 whiB - - K ko:K18955 - ko00000,ko03000 Transcription factor WhiB
NLHLMEME_01565 4.31e-53 - - - - - - - -
NLHLMEME_01567 2.43e-19 - - - - - - - -
NLHLMEME_01571 2.87e-22 - - - - - - - -
NLHLMEME_01572 9.01e-156 - - - - - - - -
NLHLMEME_01575 6.3e-57 - - - - - - - -
NLHLMEME_01576 0.0 - - - S - - - Terminase
NLHLMEME_01577 1.12e-97 - - - S - - - Phage portal protein
NLHLMEME_01578 3.63e-37 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
NLHLMEME_01579 2.74e-100 - - - S - - - Phage capsid family
NLHLMEME_01581 3.93e-23 - - - - - - - -
NLHLMEME_01582 7.3e-74 - - - - - - - -
NLHLMEME_01583 7.29e-54 - - - - - - - -
NLHLMEME_01584 2.84e-86 - - - - - - - -
NLHLMEME_01585 2.57e-141 - - - - - - - -
NLHLMEME_01586 7.1e-83 - - - - - - - -
NLHLMEME_01588 4.13e-300 - - - NT - - - phage tail tape measure protein
NLHLMEME_01590 0.0 - - - S - - - cellulase activity
NLHLMEME_01592 7.44e-46 - - - - - - - -
NLHLMEME_01600 2.18e-97 - - - V - - - Ami_2
NLHLMEME_01601 3.11e-21 - - - - - - - -
NLHLMEME_01602 6.72e-68 - - - - - - - -
NLHLMEME_01603 5.34e-38 - - - K - - - Transcriptional regulator
NLHLMEME_01606 1e-162 int8 - - L - - - Phage integrase family
NLHLMEME_01607 1.74e-112 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NLHLMEME_01608 9.33e-181 - - - G - - - Major Facilitator Superfamily
NLHLMEME_01609 1.66e-216 - 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
NLHLMEME_01610 1.31e-287 - 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
NLHLMEME_01611 2e-211 - 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
NLHLMEME_01612 1.59e-266 - - - GK - - - ROK family
NLHLMEME_01613 9.44e-193 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NLHLMEME_01614 1.01e-313 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Amidohydrolase family
NLHLMEME_01615 1.58e-127 - - - F - - - NUDIX domain
NLHLMEME_01616 0.0 pepP 3.4.11.9 - E ko:K01262 - ko00000,ko01000,ko01002 Aminopeptidase P, N-terminal domain
NLHLMEME_01617 0.0 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Mur ligase middle domain
NLHLMEME_01618 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
NLHLMEME_01619 7.52e-64 - - - V - - - Acetyltransferase (GNAT) domain
NLHLMEME_01620 1.07e-27 - - - V - - - Acetyltransferase (GNAT) domain
NLHLMEME_01621 1.42e-247 - - - V - - - Acetyltransferase (GNAT) domain
NLHLMEME_01622 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NLHLMEME_01623 1.11e-176 sigH - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NLHLMEME_01624 3.96e-69 - - - - - - - -
NLHLMEME_01625 1.64e-240 - 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
NLHLMEME_01626 2.09e-245 - 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
NLHLMEME_01627 2.06e-233 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NLHLMEME_01628 4.92e-115 ybaK - - J ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NLHLMEME_01629 1.23e-252 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NLHLMEME_01630 7.74e-173 - 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Thiamin pyrophosphokinase, vitamin B1 binding domain
NLHLMEME_01631 1.72e-157 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NLHLMEME_01632 2.72e-34 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L35
NLHLMEME_01633 7.76e-81 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NLHLMEME_01634 7.46e-245 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
NLHLMEME_01635 2.86e-201 xerD - - D ko:K03733,ko:K04763 - ko00000,ko03036 recombinase XerD
NLHLMEME_01636 4.16e-194 soj - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain protein
NLHLMEME_01637 9.39e-195 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NLHLMEME_01638 2.87e-146 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NLHLMEME_01639 9.17e-204 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX hydrolase
NLHLMEME_01640 0.0 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NLHLMEME_01641 0.0 nadB 1.4.3.16, 2.4.2.19 - H ko:K00278,ko:K00767 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
NLHLMEME_01642 4.35e-207 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Quinolinate phosphoribosyl transferase, N-terminal domain
NLHLMEME_01643 2.1e-305 iscS1 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class-V
NLHLMEME_01644 3.67e-310 nanT - - U ko:K03290,ko:K08178,ko:K08369 - ko00000,ko02000 Sugar (and other) transporter
NLHLMEME_01645 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
NLHLMEME_01646 5.21e-177 - - - V ko:K02003 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NLHLMEME_01647 1.46e-139 - - - K - - - Virulence activator alpha C-term
NLHLMEME_01648 0.0 typA - - T ko:K06207 - ko00000 Elongation factor G C-terminus
NLHLMEME_01649 5.93e-261 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
NLHLMEME_01650 2.08e-58 - - - S - - - Protein of unknown function (DUF3073)
NLHLMEME_01651 5.37e-146 - - - K - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NLHLMEME_01652 1.52e-264 - - - T - - - Histidine kinase
NLHLMEME_01653 3.72e-290 - - - EGP - - - Major Facilitator Superfamily
NLHLMEME_01654 1.22e-132 - - - I - - - Sterol carrier protein
NLHLMEME_01655 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NLHLMEME_01656 1.46e-47 - - - - - - - -
NLHLMEME_01657 8.43e-179 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Rhomboid family
NLHLMEME_01659 1.98e-100 crgA - - D - - - Involved in cell division
NLHLMEME_01660 1.56e-162 - - - S - - - Bacterial protein of unknown function (DUF881)
NLHLMEME_01661 4.11e-294 srtB 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
NLHLMEME_01662 1.11e-154 trpG 2.6.1.85, 4.1.3.27 - EH ko:K01658,ko:K01664 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 para-aminobenzoate synthase glutamine amidotransferase component II
NLHLMEME_01663 0.0 pknB 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 Protein tyrosine kinase
NLHLMEME_01664 1.32e-222 pknA 2.7.11.1 - T ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 Protein tyrosine kinase
NLHLMEME_01665 0.0 pbpA - - M ko:K05364 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
NLHLMEME_01666 0.0 rodA - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
NLHLMEME_01667 0.0 pstP 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 Sigma factor PP2C-like phosphatases
NLHLMEME_01668 2.11e-103 fhaB - - T - - - Inner membrane component of T3SS, cytoplasmic domain
NLHLMEME_01669 8.7e-166 fhaA - - T - - - Protein of unknown function (DUF2662)
NLHLMEME_01670 0.0 pepX 3.4.14.5 - E ko:K01278 ko04974,map04974 ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 Dipeptidyl peptidase IV (DPP IV) N-terminal region
NLHLMEME_01671 1.52e-270 pldB 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Serine aminopeptidase, S33
NLHLMEME_01672 4.94e-119 - - - O - - - Hsp20/alpha crystallin family
NLHLMEME_01673 5.41e-227 - - - EG - - - EamA-like transporter family
NLHLMEME_01674 2.73e-37 - - - - - - - -
NLHLMEME_01675 0.0 - - - S - - - Putative esterase
NLHLMEME_01676 0.0 lysX - - S - - - Uncharacterised conserved protein (DUF2156)
NLHLMEME_01677 4.46e-257 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NLHLMEME_01678 5.02e-169 - - - S ko:K07005 - ko00000 Pyridoxamine 5'-phosphate oxidase
NLHLMEME_01679 4.63e-253 - - - S - - - Fic/DOC family
NLHLMEME_01680 8.07e-210 - - - M - - - Glycosyltransferase like family 2
NLHLMEME_01681 0.0 - - - KL - - - Domain of unknown function (DUF3427)
NLHLMEME_01682 6.69e-98 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
NLHLMEME_01683 1.01e-68 - - - S - - - Putative heavy-metal-binding
NLHLMEME_01684 3.51e-191 - - - S ko:K11068 - ko00000,ko02042 Haemolysin-III related
NLHLMEME_01686 0.0 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NLHLMEME_01687 0.0 degP - - O ko:K08372 ko02020,map02020 ko00000,ko00001,ko01000,ko01002 Domain present in PSD-95, Dlg, and ZO-1/2.
NLHLMEME_01688 0.0 - 3.6.3.4, 3.6.3.54 - P ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 E1-E2 ATPase
NLHLMEME_01689 0.0 fprA 1.18.1.2, 1.19.1.1 - C ko:K00528 - ko00000,ko01000 Pyridine nucleotide-disulphide oxidoreductase
NLHLMEME_01690 4.08e-220 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
NLHLMEME_01692 1.09e-223 - - - EG - - - EamA-like transporter family
NLHLMEME_01693 6.59e-254 fbaA 4.1.2.13 - G ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-bisphosphate aldolase class-II
NLHLMEME_01694 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NLHLMEME_01695 0.0 - - - P ko:K03281 - ko00000 Voltage gated chloride channel
NLHLMEME_01696 3.82e-209 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NLHLMEME_01697 1.8e-81 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NLHLMEME_01698 2.31e-255 - - - K ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
NLHLMEME_01700 0.0 gtfA 2.4.1.7 GH13 G ko:K00690 ko00500,map00500 ko00000,ko00001,ko01000 Domain of unknown function (DUF1964)
NLHLMEME_01701 0.0 scrT - - G - - - Transporter major facilitator family protein
NLHLMEME_01702 1.03e-243 - - - K ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
NLHLMEME_01703 0.0 - - - EGP - - - Sugar (and other) transporter
NLHLMEME_01704 7.18e-260 ilvC 1.1.1.86 - H ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NLHLMEME_01705 7.18e-260 ilvC 1.1.1.86 - H ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NLHLMEME_01706 0.0 - 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha-amylase domain
NLHLMEME_01707 2.24e-239 - - - K - - - Psort location Cytoplasmic, score
NLHLMEME_01708 0.0 - - - M - - - cell wall anchor domain protein
NLHLMEME_01709 0.0 - - - M - - - domain protein
NLHLMEME_01710 5.58e-221 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
NLHLMEME_01711 0.0 malQ 2.4.1.25 GH77 G ko:K00705 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 4-alpha-glucanotransferase
NLHLMEME_01712 0.0 malL 2.4.1.4, 3.2.1.1, 3.2.1.20, 5.4.99.16 GH13,GH31 G ko:K01187,ko:K05341,ko:K05343 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha-amylase domain
NLHLMEME_01713 2.41e-299 malE - - G ko:K15770 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
NLHLMEME_01714 0.0 malC - - G ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NLHLMEME_01715 9.93e-213 malG - - G ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NLHLMEME_01716 8.38e-190 traX - - S - - - TraX protein
NLHLMEME_01717 1.37e-248 - - - K - - - Psort location Cytoplasmic, score
NLHLMEME_01718 0.0 - 3.2.1.1, 3.2.1.41 CBM48,GH13 M ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 ko00000,ko00001,ko01000 Aamy_C
NLHLMEME_01719 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
NLHLMEME_01720 5.28e-116 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NLHLMEME_01721 2.45e-224 dnaJ - - O ko:K03686,ko:K05516 - ko00000,ko03029,ko03036,ko03110 DnaJ molecular chaperone homology domain
NLHLMEME_01722 5.76e-134 hspR - - K ko:K13640 - ko00000,ko03000 transcriptional regulator, MerR family
NLHLMEME_01723 1.48e-128 - - - C - - - Acyl-CoA reductase (LuxC)
NLHLMEME_01724 3.22e-181 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Oxidoreductase, short chain dehydrogenase reductase family protein
NLHLMEME_01725 1.57e-163 - - - S - - - HAD hydrolase, family IA, variant 3
NLHLMEME_01726 7.43e-171 dedA1 - - S ko:K03975 - ko00000 SNARE associated Golgi protein
NLHLMEME_01727 1.02e-156 - - - D - - - bacterial-type flagellum organization
NLHLMEME_01728 1.53e-244 cpaF - - U ko:K02283 - ko00000,ko02035,ko02044 Type II IV secretion system protein
NLHLMEME_01729 7.27e-95 - - - U ko:K12510 - ko00000,ko02044 Type ii secretion system
NLHLMEME_01730 6.89e-151 - - - NU - - - Type II secretion system (T2SS), protein F
NLHLMEME_01731 3.68e-55 - - - S - - - Protein of unknown function (DUF4244)
NLHLMEME_01732 2.92e-75 - - - U - - - TadE-like protein
NLHLMEME_01733 3.01e-70 - - - S - - - TIGRFAM helicase secretion neighborhood TadE-like protein
NLHLMEME_01734 1.33e-275 - 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Diacylglycerol kinase catalytic domain protein
NLHLMEME_01735 1.98e-127 - - - K - - - Bacterial regulatory proteins, tetR family
NLHLMEME_01736 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III subunit gamma tau
NLHLMEME_01737 9.94e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NLHLMEME_01738 1.74e-273 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
NLHLMEME_01739 8.78e-46 - - - V - - - Abi-like protein
NLHLMEME_01740 1.29e-182 - - - T ko:K06950 - ko00000 HD domain
NLHLMEME_01741 9.6e-203 - - - S - - - Glutamine amidotransferase domain
NLHLMEME_01742 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
NLHLMEME_01743 3.31e-238 tatD - - L ko:K03424 - ko00000,ko01000 TatD related DNase
NLHLMEME_01744 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter
NLHLMEME_01745 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter
NLHLMEME_01746 5.54e-29 - - - S ko:K06921 - ko00000 ATPase domain predominantly from Archaea
NLHLMEME_01747 0.0 - - - S ko:K07133 - ko00000 Domain of unknown function (DUF4143)
NLHLMEME_01748 1.01e-245 - - - G - - - Glycosyl hydrolases family 43
NLHLMEME_01749 2.58e-196 - - - U ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NLHLMEME_01750 7.71e-228 - - - U ko:K02025,ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NLHLMEME_01751 2.86e-308 - - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
NLHLMEME_01752 5.57e-247 - - - K - - - helix_turn _helix lactose operon repressor
NLHLMEME_01753 0.0 - 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 Beta-galactosidase trimerisation domain
NLHLMEME_01754 0.0 - - - S ko:K07133 - ko00000 AAA domain
NLHLMEME_01755 9.82e-266 - - - EGP - - - Major Facilitator Superfamily
NLHLMEME_01757 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
NLHLMEME_01758 0.0 oppD - - P ko:K02031,ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NLHLMEME_01759 4.98e-226 oppC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 N-terminal TM domain of oligopeptide transport permease C
NLHLMEME_01760 1.23e-228 oppB1 - - EP ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NLHLMEME_01761 0.0 - 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
NLHLMEME_01762 3.19e-264 - - - S - - - Protein conserved in bacteria
NLHLMEME_01763 4.05e-60 - - - - - - - -
NLHLMEME_01764 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NLHLMEME_01765 5.33e-156 - - - - - - - -
NLHLMEME_01766 3.52e-231 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NLHLMEME_01768 0.0 - - - G - - - MFS/sugar transport protein
NLHLMEME_01769 6.86e-228 - 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NLHLMEME_01770 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
NLHLMEME_01771 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
NLHLMEME_01772 5.27e-117 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NLHLMEME_01773 0.0 - - - E ko:K03293 - ko00000 Amino acid permease
NLHLMEME_01774 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
NLHLMEME_01775 1.76e-165 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
NLHLMEME_01776 0.0 aroP - - E ko:K03293,ko:K11732 - ko00000,ko02000 aromatic amino acid transport protein AroP K03293
NLHLMEME_01777 8.13e-137 - - - S - - - Protein of unknown function, DUF624
NLHLMEME_01778 4.49e-196 - - - G ko:K02026,ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NLHLMEME_01779 3.3e-200 msmF - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NLHLMEME_01780 3.04e-231 - - - K - - - Psort location Cytoplasmic, score
NLHLMEME_01781 0.0 amyE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
NLHLMEME_01782 1.29e-132 gpm2 3.1.3.73 - G ko:K02226 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Phosphoglycerate mutase family
NLHLMEME_01783 6.43e-79 - - - S - - - Protein of unknown function (DUF4235)
NLHLMEME_01784 1.65e-22 nfrA - - C - - - Nitroreductase family
NLHLMEME_01785 4.18e-120 nfrA - - C - - - Nitroreductase family
NLHLMEME_01786 0.0 - - - S ko:K01421 - ko00000 YhgE Pip domain protein
NLHLMEME_01787 0.0 - - - S ko:K01421 - ko00000 YhgE Pip domain protein
NLHLMEME_01788 6.32e-55 - - - - - - - -
NLHLMEME_01789 0.0 - 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
NLHLMEME_01790 7.15e-197 - - - G ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NLHLMEME_01791 1.46e-212 - - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NLHLMEME_01792 1.62e-312 - - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
NLHLMEME_01793 4.45e-294 - - - GK - - - ROK family
NLHLMEME_01794 0.0 - 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Glycosyl hydrolase family 36 N-terminal domain
NLHLMEME_01795 1.77e-102 tadA 3.5.4.1, 3.5.4.33 - FJ ko:K01485,ko:K11991 ko00240,ko00330,ko01100,map00240,map00330,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NLHLMEME_01796 0.0 nhaP - - P ko:K03316 - ko00000 Sodium/hydrogen exchanger family
NLHLMEME_01797 3.06e-160 - - - S ko:K07090 - ko00000 membrane transporter protein
NLHLMEME_01798 1.25e-188 - - - S ko:K06999 - ko00000 Phospholipase/Carboxylesterase
NLHLMEME_01799 1.05e-194 - - - - - - - -
NLHLMEME_01800 6.04e-144 dcd 3.5.4.13 - F ko:K01494 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dCTP deaminase family
NLHLMEME_01801 7.05e-134 - - - - - - - -
NLHLMEME_01802 0.0 pacL2 3.6.3.8 - P ko:K01537 - ko00000,ko01000 Cation transporter/ATPase, N-terminus
NLHLMEME_01803 1.55e-20 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
NLHLMEME_01804 1.58e-112 - 2.7.1.208 - G ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NLHLMEME_01805 0.0 nagE 2.7.1.193 - G ko:K02802,ko:K02803,ko:K02804 ko00520,ko02060,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
NLHLMEME_01806 2.78e-273 - - - EGP - - - Transmembrane secretion effector
NLHLMEME_01807 2.26e-222 rlmB 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NLHLMEME_01808 1.21e-212 - 5.1.3.15 - G ko:K01792 ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Aldose 1-epimerase
NLHLMEME_01809 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
NLHLMEME_01810 0.0 - - - KLT - - - Domain of unknown function (DUF4032)
NLHLMEME_01811 7.62e-270 ugpC - - E ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NLHLMEME_01812 7.15e-176 - - - K ko:K03710 - ko00000,ko03000 UTRA domain
NLHLMEME_01813 1.55e-307 - - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
NLHLMEME_01814 3.61e-61 - 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NLHLMEME_01815 3.21e-93 - 2.7.1.194 - G ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NLHLMEME_01816 2.04e-275 - - - M - - - Glycosyltransferase like family 2
NLHLMEME_01817 1.26e-243 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NLHLMEME_01819 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NLHLMEME_01820 1.72e-114 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
NLHLMEME_01821 4.65e-57 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
NLHLMEME_01822 7.86e-92 - 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Fibronectin type III-like domain
NLHLMEME_01823 0.0 - - - KLT - - - Protein tyrosine kinase
NLHLMEME_01824 3.1e-182 - - - O - - - Thioredoxin
NLHLMEME_01826 2.8e-285 rpfB - - S ko:K21688 - ko00000 G5
NLHLMEME_01827 7.89e-216 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NLHLMEME_01828 4.64e-227 ispE 2.7.1.148 - F ko:K00919 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NLHLMEME_01829 1.19e-142 - - - S - - - LytR cell envelope-related transcriptional attenuator
NLHLMEME_01830 0.0 pcnA 2.7.7.19, 2.7.7.72 - J ko:K00970,ko:K00974 ko03013,ko03018,map03013,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 Probable RNA and SrmB- binding site of polymerase A
NLHLMEME_01831 1.41e-216 mutT4 - - L - - - Belongs to the Nudix hydrolase family
NLHLMEME_01832 0.0 - - - - - - - -
NLHLMEME_01833 0.0 mviN - - KLT ko:K03980 - ko00000,ko01011,ko02000 MviN-like protein
NLHLMEME_01834 4.24e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NLHLMEME_01835 5.16e-289 parB - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
NLHLMEME_01836 2.2e-224 parA - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain protein
NLHLMEME_01837 3.05e-160 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
NLHLMEME_01838 1.14e-118 jag - - S ko:K06346 - ko00000 Putative single-stranded nucleic acids-binding domain
NLHLMEME_01839 7.31e-114 - - - G - - - Transmembrane secretion effector
NLHLMEME_01840 3.52e-25 higA - - K ko:K21498 - ko00000,ko02048 Helix-turn-helix
NLHLMEME_01841 9.28e-311 - - - S - - - HipA-like C-terminal domain
NLHLMEME_01842 5.09e-51 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
NLHLMEME_01843 1.92e-67 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
NLHLMEME_01844 7.54e-107 - - - S - - - Cupin 2, conserved barrel domain protein
NLHLMEME_01845 6.44e-205 - - - J - - - Methyltransferase domain
NLHLMEME_01846 1.35e-79 yccF - - S - - - Inner membrane component domain
NLHLMEME_01847 2.85e-299 - - - K - - - Fic/DOC family
NLHLMEME_01849 1.18e-283 - - - L - - - ABC transporter
NLHLMEME_01850 6.34e-222 - - - L - - - ABC transporter
NLHLMEME_01851 4.68e-314 - - - V - - - MatE
NLHLMEME_01853 4.15e-39 - - - S ko:K02890,ko:K07343 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 rRNA binding
NLHLMEME_01854 2.9e-171 tetD - - K ko:K13653 - ko00000,ko03000 Arac family
NLHLMEME_01855 9.63e-260 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NLHLMEME_01856 4.1e-144 glnP2 - - E ko:K02029 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NLHLMEME_01857 2.26e-153 glnP - - E ko:K02029,ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NLHLMEME_01858 6.4e-176 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ATP binding protein of ABC transporter for glutamate aspartate K02028
NLHLMEME_01859 3.42e-199 glnH - - ET ko:K02030,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
NLHLMEME_01860 2.3e-190 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NLHLMEME_01861 0.0 pip 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 alpha/beta hydrolase fold
NLHLMEME_01862 0.0 - - - T - - - Histidine kinase
NLHLMEME_01863 1.43e-180 - - - K - - - helix_turn_helix, Lux Regulon
NLHLMEME_01864 0.0 - - - MV ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
NLHLMEME_01865 5.51e-211 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NLHLMEME_01866 0.0 - 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Aminotransferase class-V
NLHLMEME_01867 2.26e-210 pdxY 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
NLHLMEME_01868 4.48e-28 - - - L - - - Transposase and inactivated derivatives IS30 family
NLHLMEME_01869 8.76e-99 yraN - - L ko:K07460 - ko00000 Belongs to the UPF0102 family
NLHLMEME_01870 0.0 comM - - O ko:K07391 - ko00000 Magnesium chelatase, subunit ChlI C-terminal
NLHLMEME_01871 0.0 dprA - - LU ko:K04096 - ko00000 DNA recombination-mediator protein A
NLHLMEME_01872 0.0 sdhA 1.3.5.1, 1.3.5.4, 1.4.3.16 - C ko:K00239,ko:K00278 ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 Succinate dehydrogenase flavoprotein subunit
NLHLMEME_01873 3.43e-234 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
NLHLMEME_01874 3.95e-147 safC - - S - - - O-methyltransferase
NLHLMEME_01875 2.76e-216 fmt2 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
NLHLMEME_01876 1.75e-310 nhaA - - P ko:K03313 - ko00000,ko02000 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NLHLMEME_01877 4.52e-307 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I II
NLHLMEME_01879 0.0 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NLHLMEME_01880 1.56e-156 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NLHLMEME_01881 2.96e-151 clpP1 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NLHLMEME_01882 4.53e-79 - - - - - - - -
NLHLMEME_01883 1.18e-310 - - - P ko:K03281 - ko00000 Voltage gated chloride channel
NLHLMEME_01884 3.47e-303 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NLHLMEME_01885 0.0 rnd 3.1.13.5 - J ko:K03684 - ko00000,ko01000,ko03016 3'-5' exonuclease
NLHLMEME_01886 2.34e-154 - - - S - - - Protein of unknown function (DUF3000)
NLHLMEME_01887 5.19e-222 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NLHLMEME_01888 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
NLHLMEME_01889 1.5e-52 - - - - - - - -
NLHLMEME_01890 0.0 nadE 6.3.5.1 - H ko:K01950 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NLHLMEME_01891 6.89e-286 - - - S - - - Peptidase dimerisation domain
NLHLMEME_01892 3.9e-146 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NLHLMEME_01893 6.93e-281 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NLHLMEME_01894 8.96e-226 - - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 NLPA lipoprotein
NLHLMEME_01895 1.15e-200 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
NLHLMEME_01896 1.07e-238 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Membrane protein insertase, YidC Oxa1 family
NLHLMEME_01897 2.07e-73 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NLHLMEME_01898 4.62e-20 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
NLHLMEME_01899 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NLHLMEME_01900 5.94e-262 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NLHLMEME_01901 2.26e-256 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NLHLMEME_01902 5.66e-106 - - - S - - - Protein of unknown function (DUF721)
NLHLMEME_01903 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NLHLMEME_01904 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NLHLMEME_01905 6.05e-89 - - - S - - - Transmembrane domain of unknown function (DUF3566)
NLHLMEME_01906 3.55e-233 - - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
NLHLMEME_01908 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
NLHLMEME_01909 6.18e-262 - - - V - - - VanZ like family
NLHLMEME_01910 0.0 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
NLHLMEME_01911 3.64e-252 - - - S - - - Psort location CytoplasmicMembrane, score
NLHLMEME_01914 2.54e-159 - - - S ko:K07043 - ko00000 Protein of unknown function DUF45
NLHLMEME_01916 0.0 - - - S ko:K07133 - ko00000 Domain of unknown function (DUF4143)
NLHLMEME_01917 1.81e-108 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
NLHLMEME_01918 5.81e-306 - - - P ko:K03699 - ko00000,ko02042 Transporter associated domain
NLHLMEME_01919 7.26e-265 - - - S - - - AAA ATPase domain
NLHLMEME_01920 1.05e-154 cah 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
NLHLMEME_01921 1.68e-138 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 C-terminal domain of 1-Cys peroxiredoxin
NLHLMEME_01922 0.0 - 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Thioredoxin domain
NLHLMEME_01923 0.0 - 5.1.3.2 - GM ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 ADP-glyceromanno-heptose 6-epimerase activity
NLHLMEME_01924 8.73e-206 - - - - - - - -
NLHLMEME_01925 0.0 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2194)
NLHLMEME_01926 0.0 - - GT4 M ko:K21011 ko02025,map02025 ko00000,ko00001,ko01003 Domain of unknown function (DUF3492)
NLHLMEME_01927 0.0 - - - S ko:K21012 ko02025,map02025 ko00000,ko00001 Putative exopolysaccharide Exporter (EPS-E)
NLHLMEME_01928 0.0 - - - M ko:K06330 - ko00000 CotH kinase protein
NLHLMEME_01929 1.93e-203 - - - P - - - VTC domain
NLHLMEME_01930 2.97e-143 - - - S - - - Domain of unknown function (DUF4956)
NLHLMEME_01931 0.0 - 3.1.4.52 - T ko:K14051 ko02024,ko02026,map02024,map02026 ko00000,ko00001,ko01000 Putative diguanylate phosphodiesterase
NLHLMEME_01932 4.86e-123 - - - S ko:K07133 - ko00000 AAA domain
NLHLMEME_01933 0.0 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
NLHLMEME_01934 3.9e-08 - - - S ko:K07133 - ko00000 AAA domain
NLHLMEME_01935 0.0 ppc 4.1.1.31 - H ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NLHLMEME_01936 0.0 - - - S - - - Threonine/Serine exporter, ThrE
NLHLMEME_01937 0.0 - - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NLHLMEME_01938 3.07e-239 - - - S - - - Protein conserved in bacteria
NLHLMEME_01939 0.0 - - - S - - - Amidohydrolase family
NLHLMEME_01940 1.27e-309 pntB 1.6.1.2 - C ko:K00325 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
NLHLMEME_01941 3.55e-58 pntAB 1.6.1.2 - C ko:K00324 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 4TM region of pyridine nucleotide transhydrogenase, mitoch
NLHLMEME_01942 1.99e-262 pntA 1.6.1.2 - C ko:K00324 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 NAD(P) transhydrogenase subunit alpha part 1 K00324
NLHLMEME_01943 0.0 fadD2 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
NLHLMEME_01944 1.2e-120 fadD2 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
NLHLMEME_01945 3.7e-234 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NLHLMEME_01946 0.0 corC - - S - - - CBS domain
NLHLMEME_01947 1.33e-133 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NLHLMEME_01948 9.79e-278 phoH - - T ko:K06217 - ko00000 PhoH-like protein
NLHLMEME_01949 2.76e-76 hit - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
NLHLMEME_01950 8.9e-175 - 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NLHLMEME_01952 7.89e-212 spoU2 - - J - - - SpoU rRNA Methylase family
NLHLMEME_01953 1.6e-309 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NLHLMEME_01954 2.19e-142 - - - S - - - Iron-sulfur cluster assembly protein
NLHLMEME_01955 8.33e-133 iscU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
NLHLMEME_01956 1.25e-302 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NLHLMEME_01957 2.81e-184 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
NLHLMEME_01958 1.07e-301 sufD - - O ko:K09015 - ko00000 FeS assembly protein SufD
NLHLMEME_01959 0.0 sufB - - O ko:K09014 - ko00000 FeS assembly protein SufB
NLHLMEME_01960 0.0 - - - S - - - L,D-transpeptidase catalytic domain
NLHLMEME_01961 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NLHLMEME_01962 1.07e-121 - - - K - - - Psort location Cytoplasmic, score
NLHLMEME_01963 8.53e-104 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
NLHLMEME_01964 0.0 aroB 2.7.1.71, 4.2.3.4 - H ko:K01735,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NLHLMEME_01965 5.24e-278 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NLHLMEME_01966 1.01e-90 - 3.4.23.43 - S ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 Type IV leader peptidase family
NLHLMEME_01967 5.37e-255 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NLHLMEME_01968 2.12e-99 ruvX - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NLHLMEME_01969 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NLHLMEME_01970 6.59e-48 - - - - - - - -
NLHLMEME_01971 1.28e-76 - - - S - - - Bacterial protein of unknown function (DUF948)
NLHLMEME_01972 2.43e-166 - 5.4.2.12 - G ko:K15634 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Phosphoglycerate mutase family
NLHLMEME_01973 2.55e-65 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
NLHLMEME_01974 8.67e-85 - - - T - - - PemK-like, MazF-like toxin of type II toxin-antitoxin system
NLHLMEME_01975 1.03e-143 - - - E - - - Transglutaminase-like superfamily
NLHLMEME_01976 9.02e-69 - - - S - - - SdpI/YhfL protein family
NLHLMEME_01977 3.01e-117 - 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 cytidine deaminase activity
NLHLMEME_01978 5.11e-201 - - - S ko:K07010 - ko00000,ko01002 Peptidase C26
NLHLMEME_01979 5.26e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NLHLMEME_01980 7.29e-195 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
NLHLMEME_01981 1.28e-274 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
NLHLMEME_01982 1.54e-82 - - - S - - - Domain of unknown function (DUF4418)
NLHLMEME_01983 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
NLHLMEME_01984 5.15e-136 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NLHLMEME_01985 5.81e-307 pbuX - - F ko:K03458 - ko00000 Permease family
NLHLMEME_01986 1.08e-69 - - - S - - - Protein of unknown function (DUF2975)
NLHLMEME_01987 1.56e-40 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
NLHLMEME_01988 5.23e-195 - - - I - - - Serine aminopeptidase, S33
NLHLMEME_01989 6.81e-222 - - - M - - - pfam nlp p60
NLHLMEME_01990 2.15e-138 pncA 3.5.1.19 - Q ko:K08281 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Isochorismatase family
NLHLMEME_01991 1.07e-144 pepE 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Peptidase family S51
NLHLMEME_01992 1.01e-260 - - - - - - - -
NLHLMEME_01993 7.8e-141 - - - E - - - GDSL-like Lipase/Acylhydrolase family
NLHLMEME_01994 0.0 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
NLHLMEME_01995 0.0 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
NLHLMEME_01996 9.97e-287 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
NLHLMEME_01997 2.02e-77 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NLHLMEME_01998 1.01e-13 - 3.6.3.8 - P ko:K01537 - ko00000,ko01000 Cation transporter/ATPase, N-terminus
NLHLMEME_01999 1.16e-285 - - - T - - - Histidine kinase
NLHLMEME_02000 2.11e-140 - - - K - - - helix_turn_helix, Lux Regulon
NLHLMEME_02001 2.24e-146 - - - P ko:K07220 - ko00000 Protein of unknown function DUF47
NLHLMEME_02002 2.33e-240 pitB - - P ko:K03306 - ko00000 Phosphate transporter family
NLHLMEME_02003 0.0 nplT 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
NLHLMEME_02004 0.0 - - - JKL - - - helicase superfamily c-terminal domain
NLHLMEME_02005 8.43e-299 rutG - - F ko:K02824,ko:K03458 - ko00000,ko02000 Permease family
NLHLMEME_02006 2.09e-208 - - - G - - - Phosphoglycerate mutase family
NLHLMEME_02007 7.93e-140 - - - E - - - haloacid dehalogenase-like hydrolase
NLHLMEME_02008 1.49e-308 - - - EGP ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
NLHLMEME_02009 2.38e-83 gloA - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NLHLMEME_02010 3.07e-118 - - - S ko:K07090 - ko00000 Sulfite exporter TauE/SafE
NLHLMEME_02011 2.26e-37 - - - L - - - Helix-turn-helix domain
NLHLMEME_02012 6.91e-30 - - - L - - - Helix-turn-helix domain
NLHLMEME_02013 2.15e-155 - - - S ko:K07090 - ko00000 Sulfite exporter TauE/SafE
NLHLMEME_02014 0.0 - - - C ko:K06871 - ko00000 Iron-sulfur cluster-binding domain
NLHLMEME_02015 0.0 - - - P - - - Domain of unknown function (DUF4976)
NLHLMEME_02016 0.0 gtr - - U ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Sugar (and other) transporter
NLHLMEME_02017 4.91e-204 - 5.1.3.15 - G ko:K01792 ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Aldose 1-epimerase
NLHLMEME_02018 5.28e-282 - - - GK - - - ROK family
NLHLMEME_02019 2.11e-223 - 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
NLHLMEME_02020 6.11e-189 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NLHLMEME_02021 6.23e-307 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Amidohydrolase family
NLHLMEME_02022 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NLHLMEME_02023 1.45e-17 - - - EGP ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
NLHLMEME_02024 0.0 - - - U - - - Drug resistance MFS transporter, drug H antiporter-2 family
NLHLMEME_02025 7.74e-17 - - - - - - - -
NLHLMEME_02026 4.06e-152 - - - K - - - Bacterial regulatory proteins, tetR family
NLHLMEME_02028 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
NLHLMEME_02029 2.77e-119 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NLHLMEME_02030 7.45e-134 cysE - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NLHLMEME_02031 0.0 aap1 - - E ko:K03294 - ko00000 aromatic amino acid transport protein AroP K03293
NLHLMEME_02032 0.0 alr 5.1.1.1 - M ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NLHLMEME_02033 6.86e-309 dgt 3.1.5.1 - F ko:K01129 ko00230,map00230 ko00000,ko00001,ko01000 Phosphohydrolase-associated domain
NLHLMEME_02034 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NLHLMEME_02035 1.63e-199 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NLHLMEME_02036 2.82e-147 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NLHLMEME_02037 0.0 - - - EK ko:K03710,ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000,ko03000 Alanine-glyoxylate amino-transferase
NLHLMEME_02038 1.36e-267 - - - P - - - Citrate transporter
NLHLMEME_02039 9.8e-41 - - - - - - - -
NLHLMEME_02040 8.43e-51 - - - G - - - Alpha-L-arabinofuranosidase C-terminal domain
NLHLMEME_02041 1.3e-204 - - - K - - - Helix-turn-helix domain, rpiR family
NLHLMEME_02044 0.0 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
NLHLMEME_02045 3.12e-291 - - - K - - - helix_turn _helix lactose operon repressor
NLHLMEME_02046 2.94e-188 - - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 Glycosyl transferase family 2
NLHLMEME_02047 1.74e-290 - - - GM ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NLHLMEME_02048 6.02e-184 tagG - - U ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
NLHLMEME_02049 1.63e-260 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NLHLMEME_02050 0.0 rfbD 1.1.1.133, 5.1.3.13 - M ko:K00067,ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NLHLMEME_02051 1.61e-220 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NLHLMEME_02052 7.52e-287 - - - M - - - Glycosyl hydrolases family 25
NLHLMEME_02053 2.67e-24 - - - - - - - -
NLHLMEME_02054 1.5e-95 - - - L - - - Helix-turn-helix domain
NLHLMEME_02055 2.35e-158 - - - L ko:K07497 - ko00000 Integrase core domain
NLHLMEME_02056 9.73e-246 yvhJ - - K - - - Cell envelope-related transcriptional attenuator domain
NLHLMEME_02057 0.0 - - - V - - - ABC transporter permease
NLHLMEME_02058 7.64e-243 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
NLHLMEME_02062 0.0 - - - S - - - Glucosyl transferase GtrII
NLHLMEME_02063 0.0 - - - S - - - Polysaccharide pyruvyl transferase
NLHLMEME_02064 0.0 - - - M ko:K07272 - ko00000,ko01000,ko01003,ko01005 Rhamnan synthesis protein F
NLHLMEME_02065 1.16e-243 - - - I - - - Acyltransferase family
NLHLMEME_02066 2.11e-219 - 1.1.1.339 - GM ko:K19180 ko00523,ko01130,map00523,map01130 ko00000,ko00001,ko01000 NAD dependent epimerase/dehydratase family
NLHLMEME_02067 3.97e-16 - - - - - - - -
NLHLMEME_02068 2.71e-187 - - - V - - - Phage capsid family
NLHLMEME_02070 1.99e-62 - - - S - - - Phage protein Gp19/Gp15/Gp42
NLHLMEME_02071 3.08e-41 - - - - - - - -
NLHLMEME_02074 7.03e-77 - - - N - - - domain, Protein
NLHLMEME_02075 3.3e-295 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Pyridoxal-phosphate dependent enzyme
NLHLMEME_02076 7.18e-183 cobB2 - - K ko:K12410 - ko00000,ko01000 Sir2 family
NLHLMEME_02077 1.34e-95 - - - L - - - PFAM Integrase catalytic
NLHLMEME_02078 5.22e-185 - - - L - - - PFAM Integrase catalytic

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)