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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HDLMBCOA_00001	1.91e-235	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HDLMBCOA_00002	2.88e-183	yxeH	-	-	S	-	-	-	hydrolase
HDLMBCOA_00003	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HDLMBCOA_00004	1.02e-147	tal	2.2.1.2	-	F	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HDLMBCOA_00005	3.35e-305	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HDLMBCOA_00006	7.29e-61	ulaB	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system galactitol-specific IIB component
HDLMBCOA_00007	6.42e-101	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HDLMBCOA_00008	0.0	-	-	-	G	ko:K03483	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HDLMBCOA_00009	9.14e-146	gph3	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HDLMBCOA_00010	5.26e-247	-	1.1.1.14	-	C	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
HDLMBCOA_00011	8.37e-296	gatC	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HDLMBCOA_00012	6e-60	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HDLMBCOA_00013	3.99e-106	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HDLMBCOA_00014	3.03e-145	-	-	-	K	ko:K02444	-	ko00000,ko03000	DeoR C terminal sensor domain
HDLMBCOA_00015	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HDLMBCOA_00016	3.76e-180	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HDLMBCOA_00017	6.47e-95	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HDLMBCOA_00018	7.3e-210	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HDLMBCOA_00019	3.89e-205	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HDLMBCOA_00020	0.0	-	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HDLMBCOA_00021	8.09e-263	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HDLMBCOA_00022	9.03e-173	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HDLMBCOA_00023	4.66e-197	nanK	-	-	GK	-	-	-	ROK family
HDLMBCOA_00024	1.86e-210	nanA	4.1.3.3	-	EM	ko:K01639	ko00520,map00520	ko00000,ko00001,ko01000	Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
HDLMBCOA_00025	2.13e-159	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HDLMBCOA_00026	5.6e-292	-	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
HDLMBCOA_00027	4.92e-91	-	-	-	S	-	-	-	Pyrimidine dimer DNA glycosylase
HDLMBCOA_00028	2.1e-116	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
HDLMBCOA_00029	1.06e-16	-	-	-	-	-	-	-	-
HDLMBCOA_00030	1.96e-21	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
HDLMBCOA_00031	2.07e-235	katA	1.11.1.6	-	C	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	Belongs to the catalase family
HDLMBCOA_00032	3.6e-73	katA	1.11.1.6	-	C	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	Belongs to the catalase family
HDLMBCOA_00033	1.32e-101	nrp	-	-	K	ko:K16509	-	ko00000	ArsC family
HDLMBCOA_00034	7.42e-174	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HDLMBCOA_00035	3.78e-212	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HDLMBCOA_00036	9.62e-19	-	-	-	-	-	-	-	-
HDLMBCOA_00037	1.51e-85	-	-	-	KOT	ko:K07813	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01002	May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
HDLMBCOA_00038	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
HDLMBCOA_00040	4.64e-255	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HDLMBCOA_00041	0.0	pox4	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HDLMBCOA_00042	5.03e-95	-	-	-	K	-	-	-	Transcriptional regulator
HDLMBCOA_00043	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HDLMBCOA_00044	6.96e-83	pts38A	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HDLMBCOA_00045	5.88e-233	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
HDLMBCOA_00046	1.23e-129	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
HDLMBCOA_00047	3.33e-113	srlM1	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
HDLMBCOA_00048	0.0	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
HDLMBCOA_00049	1.56e-185	srlD2	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
HDLMBCOA_00050	2.53e-209	rbsU	-	-	U	ko:K06216	-	ko00000,ko02000	ribose uptake protein RbsU
HDLMBCOA_00051	4.99e-88	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HDLMBCOA_00052	7.82e-210	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HDLMBCOA_00053	9.52e-240	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HDLMBCOA_00054	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HDLMBCOA_00055	2.51e-103	-	-	-	T	-	-	-	Universal stress protein family
HDLMBCOA_00056	7.43e-130	padR	-	-	K	-	-	-	Virulence activator alpha C-term
HDLMBCOA_00057	2.71e-135	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
HDLMBCOA_00058	6.11e-187	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
HDLMBCOA_00059	3.66e-113	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HDLMBCOA_00060	4.02e-203	degV1	-	-	S	-	-	-	DegV family
HDLMBCOA_00061	1.67e-79	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
HDLMBCOA_00062	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
HDLMBCOA_00064	2.27e-140	sip3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HDLMBCOA_00065	3.56e-163	-	-	-	-	-	-	-	-
HDLMBCOA_00066	5.67e-185	-	-	-	-	-	-	-	-
HDLMBCOA_00068	2.23e-211	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HDLMBCOA_00069	1.31e-143	-	-	-	S	-	-	-	Cell surface protein
HDLMBCOA_00070	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HDLMBCOA_00071	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HDLMBCOA_00072	4.78e-173	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
HDLMBCOA_00073	2.26e-306	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
HDLMBCOA_00074	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HDLMBCOA_00075	1.55e-158	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HDLMBCOA_00076	3.74e-75	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HDLMBCOA_00077	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HDLMBCOA_00078	4.74e-266	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HDLMBCOA_00079	3.82e-51	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
HDLMBCOA_00080	7.24e-263	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HDLMBCOA_00081	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HDLMBCOA_00082	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HDLMBCOA_00083	5.95e-65	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HDLMBCOA_00084	1.59e-95	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HDLMBCOA_00085	2.69e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HDLMBCOA_00086	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HDLMBCOA_00087	3.44e-95	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HDLMBCOA_00088	8.77e-317	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HDLMBCOA_00089	4.96e-289	yttB	-	-	EGP	-	-	-	Major Facilitator
HDLMBCOA_00090	9e-184	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HDLMBCOA_00091	1.88e-291	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HDLMBCOA_00093	1.83e-195	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HDLMBCOA_00094	7.5e-147	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HDLMBCOA_00095	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HDLMBCOA_00096	5.02e-277	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HDLMBCOA_00097	2.02e-268	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
HDLMBCOA_00098	0.0	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
HDLMBCOA_00099	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HDLMBCOA_00100	0.0	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HDLMBCOA_00102	2.4e-183	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HDLMBCOA_00103	1.1e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HDLMBCOA_00104	0.0	trePP	2.4.1.216, 2.4.1.8	GH65	G	ko:K00691,ko:K03731	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65 central catalytic domain
HDLMBCOA_00105	3.21e-104	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase
HDLMBCOA_00106	4.37e-43	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein domain
HDLMBCOA_00107	2.54e-50	-	-	-	-	-	-	-	-
HDLMBCOA_00109	2.22e-169	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HDLMBCOA_00110	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HDLMBCOA_00111	2.91e-312	yycH	-	-	S	-	-	-	YycH protein
HDLMBCOA_00112	3.54e-195	yycI	-	-	S	-	-	-	YycH protein
HDLMBCOA_00113	1.71e-200	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
HDLMBCOA_00114	4.29e-253	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
HDLMBCOA_00115	6.08e-107	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HDLMBCOA_00116	3.46e-124	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDLMBCOA_00117	2.54e-305	-	-	-	C	-	-	-	Belongs to the aldehyde dehydrogenase family
HDLMBCOA_00118	8.48e-215	-	-	-	L	-	-	-	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
HDLMBCOA_00119	5.97e-157	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
HDLMBCOA_00120	1.34e-153	pnb	-	-	C	-	-	-	nitroreductase
HDLMBCOA_00121	4.95e-86	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
HDLMBCOA_00122	1.57e-150	-	-	-	S	-	-	-	Elongation factor G-binding protein, N-terminal
HDLMBCOA_00123	0.0	-	-	-	C	-	-	-	FMN_bind
HDLMBCOA_00124	0.0	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HDLMBCOA_00125	1.46e-204	-	-	-	K	-	-	-	LysR family
HDLMBCOA_00126	2.91e-94	-	-	-	C	-	-	-	FMN binding
HDLMBCOA_00127	4.48e-98	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HDLMBCOA_00128	4.06e-211	-	-	-	S	-	-	-	KR domain
HDLMBCOA_00129	5.74e-204	adc	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
HDLMBCOA_00130	4.87e-155	ydgI	-	-	C	-	-	-	Nitroreductase family
HDLMBCOA_00131	0.0	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
HDLMBCOA_00132	1.56e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HDLMBCOA_00133	8.55e-246	pva1	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HDLMBCOA_00134	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
HDLMBCOA_00135	6.86e-175	ptp1	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HDLMBCOA_00136	0.0	hpaH	1.14.14.8, 1.14.14.9	-	Q	ko:K00483,ko:K16901	ko00350,ko00380,ko01120,ko01220,map00350,map00380,map01120,map01220	ko00000,ko00001,ko01000	4-hydroxyphenylacetate
HDLMBCOA_00137	1.36e-105	-	-	-	S	-	-	-	ASCH
HDLMBCOA_00138	4.35e-165	-	-	-	F	-	-	-	glutamine amidotransferase
HDLMBCOA_00139	1.67e-220	-	-	-	K	-	-	-	WYL domain
HDLMBCOA_00140	1.63e-152	azoR	-	-	C	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HDLMBCOA_00141	0.0	fusA1	-	-	J	-	-	-	elongation factor G
HDLMBCOA_00142	7.44e-51	-	-	-	S	-	-	-	Protein of unknown function
HDLMBCOA_00143	4.69e-80	-	-	-	S	-	-	-	Protein of unknown function
HDLMBCOA_00144	4.28e-195	-	-	-	EG	-	-	-	EamA-like transporter family
HDLMBCOA_00145	7.65e-121	yfbM	-	-	K	-	-	-	FR47-like protein
HDLMBCOA_00146	5.69e-162	-	-	-	S	-	-	-	DJ-1/PfpI family
HDLMBCOA_00147	3.14e-230	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HDLMBCOA_00148	1.02e-63	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HDLMBCOA_00149	5.98e-302	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
HDLMBCOA_00150	9.01e-215	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HDLMBCOA_00151	7.76e-181	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
HDLMBCOA_00152	2.38e-99	-	-	-	-	-	-	-	-
HDLMBCOA_00153	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HDLMBCOA_00154	8.05e-179	-	-	-	-	-	-	-	-
HDLMBCOA_00155	4.07e-05	-	-	-	-	-	-	-	-
HDLMBCOA_00156	1.56e-183	ant1	2.7.7.47	-	H	ko:K00984	-	ko00000,ko01000,ko01504	Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
HDLMBCOA_00157	1.67e-54	-	-	-	-	-	-	-	-
HDLMBCOA_00158	4.29e-166	-	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HDLMBCOA_00159	9.79e-192	-	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HDLMBCOA_00160	1.84e-235	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
HDLMBCOA_00161	1.39e-156	rcfB	-	-	K	-	-	-	Crp-like helix-turn-helix domain
HDLMBCOA_00162	7.9e-306	larA	5.1.2.1	-	S	ko:K22373	ko00620,map00620	ko00000,ko00001,ko01000	Domain of unknown function (DUF2088)
HDLMBCOA_00163	2.65e-162	larB	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
HDLMBCOA_00164	4.1e-179	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HDLMBCOA_00165	6.32e-99	larC2	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Protein of unknown function DUF111
HDLMBCOA_00166	1.19e-170	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HDLMBCOA_00167	5.24e-193	larE	-	-	S	ko:K06864	-	ko00000	NAD synthase
HDLMBCOA_00168	1.23e-227	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HDLMBCOA_00169	6.51e-176	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HDLMBCOA_00170	1.18e-188	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HDLMBCOA_00171	1.48e-140	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HDLMBCOA_00172	4.15e-261	thiP	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
HDLMBCOA_00173	1.02e-175	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
HDLMBCOA_00174	0.0	-	-	-	L	-	-	-	HIRAN domain
HDLMBCOA_00175	1.75e-61	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HDLMBCOA_00176	8.53e-29	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HDLMBCOA_00177	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HDLMBCOA_00178	1.27e-159	-	-	-	-	-	-	-	-
HDLMBCOA_00179	5.08e-192	-	-	-	I	-	-	-	Alpha/beta hydrolase family
HDLMBCOA_00180	9.62e-244	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HDLMBCOA_00181	1.34e-29	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HDLMBCOA_00182	3.08e-179	-	-	-	-	-	-	-	-
HDLMBCOA_00183	9.51e-135	-	-	-	-	-	-	-	-
HDLMBCOA_00184	2.64e-141	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
HDLMBCOA_00185	4.61e-87	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
HDLMBCOA_00186	6.77e-284	-	-	-	-	-	-	-	-
HDLMBCOA_00187	6.04e-51	-	-	-	-	-	-	-	-
HDLMBCOA_00188	1.02e-260	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HDLMBCOA_00189	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HDLMBCOA_00190	1.91e-66	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
HDLMBCOA_00191	7.08e-131	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
HDLMBCOA_00192	1.73e-108	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HDLMBCOA_00193	7.08e-250	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HDLMBCOA_00194	2.19e-163	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
HDLMBCOA_00195	7.1e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
HDLMBCOA_00196	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HDLMBCOA_00197	2.07e-240	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HDLMBCOA_00198	1.18e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HDLMBCOA_00199	2.9e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HDLMBCOA_00200	4.48e-261	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HDLMBCOA_00201	1.29e-200	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HDLMBCOA_00202	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HDLMBCOA_00203	5.89e-204	-	-	-	S	-	-	-	Tetratricopeptide repeat
HDLMBCOA_00204	4.38e-286	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HDLMBCOA_00205	3.21e-288	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HDLMBCOA_00206	7.8e-300	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HDLMBCOA_00207	9.6e-143	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HDLMBCOA_00208	1.3e-65	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
HDLMBCOA_00209	6.47e-95	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HDLMBCOA_00210	5.12e-31	-	-	-	-	-	-	-	-
HDLMBCOA_00211	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HDLMBCOA_00212	1.62e-172	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HDLMBCOA_00213	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HDLMBCOA_00214	1.17e-116	epsB	-	-	M	-	-	-	biosynthesis protein
HDLMBCOA_00215	1.09e-33	epsB	-	-	M	-	-	-	biosynthesis protein
HDLMBCOA_00216	2.02e-156	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HDLMBCOA_00217	5.54e-189	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
HDLMBCOA_00218	8.71e-231	cps4D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
HDLMBCOA_00219	1.91e-163	tuaA	-	-	M	-	-	-	Bacterial sugar transferase
HDLMBCOA_00220	1.81e-86	cps4F	-	-	M	-	-	-	Glycosyl transferases group 1
HDLMBCOA_00221	8.84e-137	cps4F	-	-	M	-	-	-	Glycosyl transferases group 1
HDLMBCOA_00222	2.26e-243	cps4G	-	-	M	-	-	-	Glycosyltransferase Family 4
HDLMBCOA_00223	2.22e-296	-	-	-	-	-	-	-	-
HDLMBCOA_00224	3.4e-228	cps4I	-	-	M	-	-	-	Glycosyltransferase like family 2
HDLMBCOA_00225	0.0	cps4J	-	-	S	-	-	-	MatE
HDLMBCOA_00226	0.0	-	3.1.4.53	-	S	ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
HDLMBCOA_00227	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
HDLMBCOA_00228	4.24e-218	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HDLMBCOA_00229	3.02e-175	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
HDLMBCOA_00230	1.55e-311	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HDLMBCOA_00231	6.62e-62	-	-	-	-	-	-	-	-
HDLMBCOA_00232	8.34e-228	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HDLMBCOA_00233	7.09e-180	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HDLMBCOA_00234	1.84e-67	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
HDLMBCOA_00235	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HDLMBCOA_00236	1.52e-120	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HDLMBCOA_00237	3.58e-129	-	-	-	K	-	-	-	Helix-turn-helix domain
HDLMBCOA_00238	6.75e-269	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HDLMBCOA_00239	2.84e-75	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
HDLMBCOA_00240	6.34e-178	-	-	-	Q	-	-	-	Methyltransferase
HDLMBCOA_00241	1.75e-43	-	-	-	-	-	-	-	-
HDLMBCOA_00242	5.77e-75	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HDLMBCOA_00247	1.17e-37	-	-	-	E	-	-	-	Zn peptidase
HDLMBCOA_00248	3.54e-32	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HDLMBCOA_00252	1.7e-78	-	-	-	S	-	-	-	DNA binding
HDLMBCOA_00261	1.7e-26	-	-	-	-	-	-	-	-
HDLMBCOA_00263	7.43e-119	-	-	-	S	-	-	-	Bacteriophage Mu Gam like protein
HDLMBCOA_00264	1.97e-151	-	-	-	S	-	-	-	AAA domain
HDLMBCOA_00265	7.25e-103	-	-	-	S	-	-	-	Protein of unknown function (DUF669)
HDLMBCOA_00266	8.06e-165	-	-	-	S	-	-	-	Putative HNHc nuclease
HDLMBCOA_00268	1.56e-40	-	-	-	L	-	-	-	Conserved phage C-terminus (Phg_2220_C)
HDLMBCOA_00269	4.15e-187	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
HDLMBCOA_00271	9.75e-61	-	-	-	-	-	-	-	-
HDLMBCOA_00272	9.62e-08	-	-	-	-	-	-	-	-
HDLMBCOA_00273	4.05e-80	-	-	-	S	-	-	-	methyltransferase activity
HDLMBCOA_00274	9.28e-12	-	-	-	S	-	-	-	YopX protein
HDLMBCOA_00276	5.23e-83	-	-	-	S	-	-	-	Transcriptional regulator, RinA family
HDLMBCOA_00277	1.52e-69	-	-	-	S	-	-	-	Domain of unknown function (DUF4145)
HDLMBCOA_00280	9.96e-79	-	-	-	V	-	-	-	HNH nucleases
HDLMBCOA_00281	7.16e-51	-	-	-	L	-	-	-	Phage terminase, small subunit
HDLMBCOA_00282	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
HDLMBCOA_00284	3.46e-180	-	-	-	S	-	-	-	Phage portal protein
HDLMBCOA_00285	6.66e-100	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
HDLMBCOA_00286	3.31e-148	-	-	-	S	-	-	-	Phage capsid family
HDLMBCOA_00287	5.83e-31	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HDLMBCOA_00288	3.13e-17	-	-	-	S	-	-	-	Phage head-tail joining protein
HDLMBCOA_00289	3.22e-37	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
HDLMBCOA_00290	1.77e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF806)
HDLMBCOA_00291	1.77e-94	-	-	-	S	-	-	-	Phage tail tube protein
HDLMBCOA_00292	1.5e-18	-	-	-	S	-	-	-	Phage tail assembly chaperone proteins, TAC
HDLMBCOA_00294	1.51e-271	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
HDLMBCOA_00295	0.0	-	-	-	S	-	-	-	Phage tail protein
HDLMBCOA_00296	0.0	-	-	-	S	-	-	-	Phage minor structural protein
HDLMBCOA_00297	1.94e-60	-	-	-	-	-	-	-	-
HDLMBCOA_00300	8.31e-70	-	-	-	-	-	-	-	-
HDLMBCOA_00301	7.55e-250	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HDLMBCOA_00302	3.19e-50	-	-	-	S	-	-	-	Haemolysin XhlA
HDLMBCOA_00303	2.63e-55	-	-	-	S	-	-	-	Bacteriophage holin
HDLMBCOA_00305	1.96e-293	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Cell cycle protein
HDLMBCOA_00306	0.0	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HDLMBCOA_00307	3.82e-184	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HDLMBCOA_00308	2.21e-281	ywtF_2	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
HDLMBCOA_00309	2.19e-131	-	-	-	L	-	-	-	Helix-turn-helix domain
HDLMBCOA_00310	1.14e-226	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyltransferase like family 2
HDLMBCOA_00311	3.81e-87	-	-	-	-	-	-	-	-
HDLMBCOA_00312	1.38e-98	-	-	-	-	-	-	-	-
HDLMBCOA_00313	1.56e-276	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
HDLMBCOA_00314	7.8e-123	-	-	-	-	-	-	-	-
HDLMBCOA_00315	7.22e-149	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HDLMBCOA_00316	3.13e-47	ynzC	-	-	S	-	-	-	UPF0291 protein
HDLMBCOA_00317	3.96e-44	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
HDLMBCOA_00318	8.8e-155	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
HDLMBCOA_00319	2.11e-171	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
HDLMBCOA_00320	5.67e-64	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
HDLMBCOA_00321	1.92e-239	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HDLMBCOA_00322	8.37e-172	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
HDLMBCOA_00323	6.33e-185	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HDLMBCOA_00324	1.88e-194	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HDLMBCOA_00325	3.01e-165	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HDLMBCOA_00326	9.83e-113	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HDLMBCOA_00327	2.18e-185	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HDLMBCOA_00328	8.76e-220	dgoD	4.2.1.6, 4.2.1.8	-	M	ko:K01684,ko:K08323	ko00040,ko00052,ko01100,ko01120,map00040,map00052,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Mandelate racemase muconate lactonizing enzyme
HDLMBCOA_00329	1.82e-185	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
HDLMBCOA_00330	8.5e-215	yflS	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HDLMBCOA_00331	7.86e-160	-	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HDLMBCOA_00332	2.62e-89	-	-	-	K	-	-	-	LysR substrate binding domain
HDLMBCOA_00333	4.48e-271	gudD	4.2.1.40	-	M	ko:K01706	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain
HDLMBCOA_00334	2.74e-63	-	-	-	-	-	-	-	-
HDLMBCOA_00335	8.55e-246	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HDLMBCOA_00336	0.0	xylP2	-	-	G	-	-	-	symporter
HDLMBCOA_00337	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HDLMBCOA_00338	1.2e-281	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
HDLMBCOA_00339	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HDLMBCOA_00340	2.41e-66	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
HDLMBCOA_00341	1.43e-155	azlC	-	-	E	-	-	-	branched-chain amino acid
HDLMBCOA_00342	1.75e-47	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HDLMBCOA_00343	1.96e-168	-	-	-	-	-	-	-	-
HDLMBCOA_00344	7.8e-152	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HDLMBCOA_00345	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HDLMBCOA_00346	7.79e-112	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HDLMBCOA_00347	1.36e-77	-	-	-	-	-	-	-	-
HDLMBCOA_00348	2.94e-155	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
HDLMBCOA_00349	1.78e-42	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HDLMBCOA_00350	2.66e-168	-	-	-	S	-	-	-	Putative threonine/serine exporter
HDLMBCOA_00351	7.76e-100	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HDLMBCOA_00352	2.34e-242	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HDLMBCOA_00353	4.15e-153	-	-	-	I	-	-	-	phosphatase
HDLMBCOA_00354	3.88e-198	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HDLMBCOA_00355	7.14e-128	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HDLMBCOA_00356	1.7e-118	-	-	-	K	-	-	-	Transcriptional regulator
HDLMBCOA_00357	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HDLMBCOA_00358	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
HDLMBCOA_00359	1.29e-153	dacB	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
HDLMBCOA_00360	1.11e-148	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HDLMBCOA_00361	1.62e-294	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HDLMBCOA_00369	9.78e-102	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
HDLMBCOA_00370	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HDLMBCOA_00371	1.16e-140	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDLMBCOA_00372	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HDLMBCOA_00373	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HDLMBCOA_00374	8.58e-149	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
HDLMBCOA_00375	4.19e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HDLMBCOA_00376	1.19e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HDLMBCOA_00377	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HDLMBCOA_00378	4.46e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HDLMBCOA_00379	4.34e-145	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HDLMBCOA_00380	9.83e-141	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HDLMBCOA_00381	1.6e-59	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HDLMBCOA_00382	6.61e-193	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HDLMBCOA_00383	1.85e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HDLMBCOA_00384	3.59e-69	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HDLMBCOA_00385	5.46e-152	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HDLMBCOA_00386	8.29e-100	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HDLMBCOA_00387	1.11e-33	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HDLMBCOA_00388	1.96e-54	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HDLMBCOA_00389	2.98e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HDLMBCOA_00390	4.1e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HDLMBCOA_00391	3.53e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HDLMBCOA_00392	4.99e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HDLMBCOA_00393	2.14e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HDLMBCOA_00394	1.75e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HDLMBCOA_00395	5.32e-109	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HDLMBCOA_00396	8.44e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HDLMBCOA_00397	1.32e-91	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HDLMBCOA_00398	3.44e-299	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HDLMBCOA_00399	1.84e-160	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HDLMBCOA_00400	9.87e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HDLMBCOA_00401	9.65e-79	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HDLMBCOA_00402	7.71e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HDLMBCOA_00403	2.19e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HDLMBCOA_00404	7.76e-81	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HDLMBCOA_00405	1.02e-233	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HDLMBCOA_00406	1.41e-122	hepA	2.5.1.30	-	S	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase component I
HDLMBCOA_00407	5.37e-112	-	-	-	S	-	-	-	NusG domain II
HDLMBCOA_00408	0.0	ndh	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HDLMBCOA_00409	3.19e-194	-	-	-	S	-	-	-	FMN_bind
HDLMBCOA_00410	1.07e-264	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HDLMBCOA_00411	1.98e-197	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HDLMBCOA_00412	2.01e-211	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HDLMBCOA_00413	2.39e-184	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HDLMBCOA_00414	3.06e-194	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HDLMBCOA_00415	4.58e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HDLMBCOA_00416	8.98e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HDLMBCOA_00417	4.92e-209	yitS	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HDLMBCOA_00418	3.73e-53	-	-	-	S	-	-	-	Membrane
HDLMBCOA_00419	1.49e-146	-	-	-	S	-	-	-	Membrane
HDLMBCOA_00420	2.23e-260	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
HDLMBCOA_00421	0.0	tkt2	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HDLMBCOA_00422	6.45e-209	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HDLMBCOA_00423	3.3e-235	aroF	2.5.1.54	-	E	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	DAHP synthetase I family
HDLMBCOA_00424	1.23e-251	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HDLMBCOA_00425	0.0	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HDLMBCOA_00426	7.49e-18	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HDLMBCOA_00427	1.42e-27	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HDLMBCOA_00428	1.41e-147	-	4.2.1.2, 4.2.1.32	-	C	ko:K01676,ko:K03780	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible hydration of fumarate to (S)- malate
HDLMBCOA_00429	4.28e-225	ttdA	4.2.1.32	-	C	ko:K03779	ko00630,map00630	ko00000,ko00001,ko01000	Fumarate hydratase (Fumerase)
HDLMBCOA_00430	1.28e-253	-	-	-	K	-	-	-	Helix-turn-helix domain
HDLMBCOA_00431	1.57e-196	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HDLMBCOA_00432	2.04e-170	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HDLMBCOA_00433	3.54e-180	mtsB	-	-	U	ko:K19972,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HDLMBCOA_00434	2.11e-222	mntA	-	-	P	ko:K19975,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HDLMBCOA_00435	1.18e-66	-	-	-	-	-	-	-	-
HDLMBCOA_00436	9.2e-215	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HDLMBCOA_00437	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HDLMBCOA_00438	8.69e-230	citR	-	-	K	-	-	-	sugar-binding domain protein
HDLMBCOA_00439	1.92e-264	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
HDLMBCOA_00440	5.31e-242	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HDLMBCOA_00441	1.23e-58	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
HDLMBCOA_00442	9.11e-208	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
HDLMBCOA_00443	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
HDLMBCOA_00444	1.96e-99	yejC	-	-	S	-	-	-	Protein of unknown function (DUF1003)
HDLMBCOA_00445	1.33e-67	XK27_08430	-	-	S	-	-	-	Staphylococcal protein of unknown function (DUF960)
HDLMBCOA_00447	2.45e-224	pmrB	-	-	EGP	-	-	-	Major Facilitator Superfamily
HDLMBCOA_00448	4.87e-191	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
HDLMBCOA_00449	2.37e-65	-	-	-	-	-	-	-	-
HDLMBCOA_00450	2.29e-36	-	-	-	-	-	-	-	-
HDLMBCOA_00451	4.61e-167	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
HDLMBCOA_00452	5.83e-100	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
HDLMBCOA_00453	1.11e-205	-	-	-	S	-	-	-	EDD domain protein, DegV family
HDLMBCOA_00454	1.97e-87	-	-	-	K	-	-	-	Transcriptional regulator
HDLMBCOA_00455	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
HDLMBCOA_00456	3.47e-38	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HDLMBCOA_00457	4.63e-103	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HDLMBCOA_00458	4.87e-205	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDLMBCOA_00459	1.27e-115	-	-	-	F	-	-	-	NUDIX domain
HDLMBCOA_00461	3.42e-176	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2087)
HDLMBCOA_00462	2.08e-92	-	-	-	S	-	-	-	LuxR family transcriptional regulator
HDLMBCOA_00463	2.24e-167	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	Chloramphenicol acetyltransferase
HDLMBCOA_00465	7.75e-93	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
HDLMBCOA_00466	2.01e-145	-	-	-	G	-	-	-	Phosphoglycerate mutase family
HDLMBCOA_00467	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HDLMBCOA_00468	1.71e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
HDLMBCOA_00469	1.9e-115	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HDLMBCOA_00470	9.72e-225	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HDLMBCOA_00471	1.65e-97	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HDLMBCOA_00472	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HDLMBCOA_00473	5.04e-82	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
HDLMBCOA_00474	3.28e-87	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
HDLMBCOA_00475	8.53e-268	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	FAD dependent oxidoreductase
HDLMBCOA_00476	3.69e-187	-	-	-	S	-	-	-	hydrolase activity, acting on ester bonds
HDLMBCOA_00477	6.79e-249	-	-	-	-	-	-	-	-
HDLMBCOA_00478	1.9e-156	-	-	-	P	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HDLMBCOA_00479	4.35e-159	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HDLMBCOA_00480	1.38e-232	-	-	-	V	-	-	-	LD-carboxypeptidase
HDLMBCOA_00481	2.04e-310	-	-	-	M	ko:K07273	-	ko00000	hydrolase, family 25
HDLMBCOA_00482	1.66e-101	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HDLMBCOA_00483	3.46e-267	mccF	-	-	V	-	-	-	LD-carboxypeptidase
HDLMBCOA_00484	9.63e-307	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
HDLMBCOA_00485	9.19e-95	-	-	-	S	-	-	-	SnoaL-like domain
HDLMBCOA_00486	4.87e-185	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
HDLMBCOA_00487	1.55e-309	-	-	-	P	-	-	-	Major Facilitator Superfamily
HDLMBCOA_00488	1.26e-61	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HDLMBCOA_00489	1.44e-282	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HDLMBCOA_00491	9.98e-75	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HDLMBCOA_00492	2.12e-142	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HDLMBCOA_00493	3.6e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HDLMBCOA_00494	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
HDLMBCOA_00495	8.03e-229	phnT	3.6.3.30	-	P	ko:K02010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HDLMBCOA_00496	8.06e-234	ftpB	-	-	P	ko:K02012	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HDLMBCOA_00497	0.0	ftpA	-	-	P	ko:K02011	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HDLMBCOA_00498	5.32e-109	-	-	-	T	-	-	-	Universal stress protein family
HDLMBCOA_00499	1.58e-203	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HDLMBCOA_00500	2.45e-142	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HDLMBCOA_00501	2.32e-238	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HDLMBCOA_00503	6.56e-165	dnaD	-	-	L	ko:K02086	-	ko00000	Replication initiation and membrane attachment
HDLMBCOA_00504	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HDLMBCOA_00505	3.1e-289	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HDLMBCOA_00506	2.53e-107	ypmB	-	-	S	-	-	-	protein conserved in bacteria
HDLMBCOA_00507	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HDLMBCOA_00508	1.48e-217	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
HDLMBCOA_00509	1.1e-230	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
HDLMBCOA_00510	3.58e-262	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
HDLMBCOA_00511	8.61e-251	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HDLMBCOA_00512	3.36e-247	galM2	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HDLMBCOA_00513	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HDLMBCOA_00514	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HDLMBCOA_00515	1.38e-156	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HDLMBCOA_00516	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
HDLMBCOA_00517	1.57e-191	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HDLMBCOA_00518	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
HDLMBCOA_00519	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HDLMBCOA_00520	3.23e-58	-	-	-	-	-	-	-	-
HDLMBCOA_00521	1.77e-66	-	-	-	-	-	-	-	-
HDLMBCOA_00522	5.03e-182	-	-	-	U	ko:K10716	-	ko00000,ko02000	Ion channel
HDLMBCOA_00523	1.48e-218	-	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
HDLMBCOA_00524	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HDLMBCOA_00525	8.39e-38	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
HDLMBCOA_00526	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HDLMBCOA_00527	1.06e-53	-	-	-	-	-	-	-	-
HDLMBCOA_00528	4e-40	-	-	-	S	-	-	-	CsbD-like
HDLMBCOA_00529	2.22e-55	-	-	-	S	-	-	-	transglycosylase associated protein
HDLMBCOA_00530	5.79e-21	-	-	-	-	-	-	-	-
HDLMBCOA_00531	1.51e-48	-	-	-	-	-	-	-	-
HDLMBCOA_00532	1.56e-78	-	-	-	L	-	-	-	Transposase DDE domain
HDLMBCOA_00533	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HDLMBCOA_00534	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HDLMBCOA_00535	6.18e-197	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	YmdB-like protein
HDLMBCOA_00536	6.57e-291	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HDLMBCOA_00537	2.43e-264	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HDLMBCOA_00538	3.83e-295	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HDLMBCOA_00539	1.92e-127	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HDLMBCOA_00540	4.71e-171	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
HDLMBCOA_00541	0.0	ymfH	-	-	S	-	-	-	Peptidase M16
HDLMBCOA_00542	5.88e-295	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
HDLMBCOA_00543	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HDLMBCOA_00544	2.61e-199	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HDLMBCOA_00545	9.09e-149	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HDLMBCOA_00546	1.89e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HDLMBCOA_00547	1.23e-187	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
HDLMBCOA_00548	3.81e-150	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HDLMBCOA_00549	9.47e-115	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
HDLMBCOA_00550	3.76e-184	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HDLMBCOA_00551	1.74e-211	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
HDLMBCOA_00552	1.15e-150	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
HDLMBCOA_00553	3.28e-315	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HDLMBCOA_00554	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HDLMBCOA_00555	3.56e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HDLMBCOA_00556	7.78e-300	gshF	6.3.2.2	-	H	ko:K01919,ko:K16786,ko:K16787	ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the glutamate--cysteine ligase type 1 family
HDLMBCOA_00557	7.66e-292	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HDLMBCOA_00558	9.04e-278	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HDLMBCOA_00560	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HDLMBCOA_00561	5.28e-105	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
HDLMBCOA_00562	2.15e-137	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HDLMBCOA_00563	4.02e-145	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
HDLMBCOA_00564	4e-105	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HDLMBCOA_00565	2.6e-141	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
HDLMBCOA_00566	4.54e-59	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HDLMBCOA_00567	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HDLMBCOA_00568	4.9e-301	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HDLMBCOA_00569	1.34e-52	-	-	-	-	-	-	-	-
HDLMBCOA_00570	2.37e-107	uspA	-	-	T	-	-	-	universal stress protein
HDLMBCOA_00571	8.1e-261	bla2	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HDLMBCOA_00572	4.7e-207	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HDLMBCOA_00573	0.0	glpQ3	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
HDLMBCOA_00574	3.78e-272	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HDLMBCOA_00575	7.55e-242	-	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HDLMBCOA_00576	3.26e-227	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
HDLMBCOA_00577	3.34e-215	hicD3	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HDLMBCOA_00578	3.03e-191	metQ	-	-	M	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HDLMBCOA_00579	2.1e-151	metI	-	-	U	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HDLMBCOA_00580	2.24e-239	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HDLMBCOA_00581	3.2e-64	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
HDLMBCOA_00582	2.15e-280	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HDLMBCOA_00583	2.54e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
HDLMBCOA_00584	1.52e-57	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
HDLMBCOA_00585	8.33e-230	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
HDLMBCOA_00586	1.68e-132	-	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HDLMBCOA_00587	2.94e-315	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HDLMBCOA_00588	5.95e-74	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HDLMBCOA_00589	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HDLMBCOA_00590	9.14e-213	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HDLMBCOA_00591	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HDLMBCOA_00592	1.37e-116	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HDLMBCOA_00593	7.68e-77	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HDLMBCOA_00594	3.66e-37	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HDLMBCOA_00595	6.85e-165	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HDLMBCOA_00596	1.44e-293	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
HDLMBCOA_00597	7.81e-148	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HDLMBCOA_00598	7.15e-296	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HDLMBCOA_00599	7.28e-243	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HDLMBCOA_00600	3.44e-204	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HDLMBCOA_00601	1.88e-251	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HDLMBCOA_00602	5e-141	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HDLMBCOA_00603	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
HDLMBCOA_00604	1.83e-175	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
HDLMBCOA_00605	4.95e-250	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HDLMBCOA_00606	2.65e-245	ampC	-	-	V	-	-	-	Beta-lactamase
HDLMBCOA_00607	2.1e-41	-	-	-	-	-	-	-	-
HDLMBCOA_00608	4.71e-74	-	-	-	S	-	-	-	SdpI/YhfL protein family
HDLMBCOA_00609	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HDLMBCOA_00610	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	Bacterial regulatory proteins, gntR family
HDLMBCOA_00611	1.02e-277	araT2	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HDLMBCOA_00612	4.06e-182	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HDLMBCOA_00613	3.59e-26	-	-	-	-	-	-	-	-
HDLMBCOA_00614	2.09e-169	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HDLMBCOA_00615	5.73e-208	mleR	-	-	K	-	-	-	LysR family
HDLMBCOA_00616	1.29e-148	-	-	-	GM	-	-	-	NAD(P)H-binding
HDLMBCOA_00617	3.86e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HDLMBCOA_00618	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HDLMBCOA_00619	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HDLMBCOA_00620	9.44e-219	oroP	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
HDLMBCOA_00621	6.64e-146	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HDLMBCOA_00622	1.55e-161	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HDLMBCOA_00623	1.04e-218	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HDLMBCOA_00624	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HDLMBCOA_00625	3.36e-272	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HDLMBCOA_00626	1.95e-309	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HDLMBCOA_00627	1.42e-219	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HDLMBCOA_00628	7.13e-123	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HDLMBCOA_00629	0.0	pucR_2	-	-	QT	ko:K09684	-	ko00000,ko03000	Purine catabolism regulatory protein-like family
HDLMBCOA_00630	3.1e-305	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
HDLMBCOA_00631	5.67e-280	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
HDLMBCOA_00632	1.29e-205	-	-	-	GM	-	-	-	NmrA-like family
HDLMBCOA_00633	1.25e-199	-	-	-	T	-	-	-	EAL domain
HDLMBCOA_00634	2.62e-121	-	-	-	-	-	-	-	-
HDLMBCOA_00635	0.0	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
HDLMBCOA_00636	4.17e-163	-	-	-	E	-	-	-	Methionine synthase
HDLMBCOA_00637	9.06e-279	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HDLMBCOA_00638	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HDLMBCOA_00639	5.35e-133	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HDLMBCOA_00640	2.97e-243	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HDLMBCOA_00641	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HDLMBCOA_00642	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HDLMBCOA_00643	1.63e-162	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HDLMBCOA_00644	1.17e-55	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HDLMBCOA_00645	3.39e-168	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HDLMBCOA_00646	2.87e-270	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HDLMBCOA_00647	3.77e-104	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HDLMBCOA_00648	7.9e-305	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
HDLMBCOA_00649	9.92e-143	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HDLMBCOA_00650	2.01e-243	lplL	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Bacterial lipoate protein ligase C-terminus
HDLMBCOA_00651	2.04e-189	ptp3	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HDLMBCOA_00652	3.44e-152	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
HDLMBCOA_00653	4.15e-191	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HDLMBCOA_00654	3.7e-233	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
HDLMBCOA_00655	2.05e-178	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDLMBCOA_00656	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HDLMBCOA_00657	4.76e-56	-	-	-	-	-	-	-	-
HDLMBCOA_00658	8.2e-81	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
HDLMBCOA_00659	9.21e-211	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDLMBCOA_00660	3.41e-190	-	-	-	-	-	-	-	-
HDLMBCOA_00661	2.7e-104	usp5	-	-	T	-	-	-	universal stress protein
HDLMBCOA_00662	1.08e-47	-	-	-	-	-	-	-	-
HDLMBCOA_00663	4.02e-95	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
HDLMBCOA_00664	5.04e-114	-	-	-	-	-	-	-	-
HDLMBCOA_00665	4.87e-66	-	-	-	-	-	-	-	-
HDLMBCOA_00666	4.79e-13	-	-	-	-	-	-	-	-
HDLMBCOA_00667	8.32e-297	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HDLMBCOA_00668	1.16e-110	-	-	-	F	-	-	-	belongs to the nudix hydrolase family
HDLMBCOA_00669	4.34e-151	-	-	-	-	-	-	-	-
HDLMBCOA_00670	1.21e-69	-	-	-	-	-	-	-	-
HDLMBCOA_00672	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HDLMBCOA_00673	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
HDLMBCOA_00674	1.33e-185	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HDLMBCOA_00675	4.72e-40	-	-	-	S	-	-	-	Pentapeptide repeats (8 copies)
HDLMBCOA_00676	1.76e-143	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HDLMBCOA_00677	3.24e-132	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
HDLMBCOA_00678	2.26e-91	-	-	-	FG	-	-	-	Scavenger mRNA decapping enzyme C-term binding
HDLMBCOA_00679	1.62e-173	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HDLMBCOA_00680	3.94e-49	XK27_01315	-	-	S	-	-	-	Protein of unknown function (DUF2829)
HDLMBCOA_00681	9.97e-269	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HDLMBCOA_00682	3.64e-293	-	-	-	S	-	-	-	Sterol carrier protein domain
HDLMBCOA_00683	1.1e-93	-	-	-	L	-	-	-	DnaD domain protein
HDLMBCOA_00684	1.18e-191	-	-	-	S	-	-	-	IstB-like ATP binding protein
HDLMBCOA_00687	6.14e-86	-	-	-	L	-	-	-	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HDLMBCOA_00688	8.89e-20	-	-	-	S	-	-	-	YjzC-like protein
HDLMBCOA_00689	1.02e-35	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HDLMBCOA_00691	7.92e-07	-	-	-	-	-	-	-	-
HDLMBCOA_00692	1.75e-112	-	-	-	S	-	-	-	methyltransferase activity
HDLMBCOA_00694	3.17e-37	-	-	-	S	-	-	-	YopX protein
HDLMBCOA_00695	1.16e-14	-	-	-	-	-	-	-	-
HDLMBCOA_00696	1.06e-25	-	-	-	-	-	-	-	-
HDLMBCOA_00701	2.43e-34	-	-	-	S	-	-	-	Protein of unknown function (DUF2829)
HDLMBCOA_00702	3.41e-61	-	-	-	L	-	-	-	transposase activity
HDLMBCOA_00703	7.33e-237	-	-	-	S	-	-	-	Phage terminase, large subunit, PBSX family
HDLMBCOA_00704	4.71e-138	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
HDLMBCOA_00705	2.3e-52	-	-	-	S	-	-	-	Phage minor capsid protein 2
HDLMBCOA_00708	3.01e-136	-	-	-	-	-	-	-	-
HDLMBCOA_00709	0.000271	-	-	-	-	-	-	-	-
HDLMBCOA_00714	1.86e-58	-	-	-	N	-	-	-	domain, Protein
HDLMBCOA_00717	2.54e-126	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
HDLMBCOA_00719	1.31e-121	-	-	-	S	-	-	-	Prophage endopeptidase tail
HDLMBCOA_00721	1.13e-10	-	-	-	-	-	-	-	-
HDLMBCOA_00722	3.23e-260	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
HDLMBCOA_00726	3.49e-222	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HDLMBCOA_00727	5.1e-47	-	-	-	S	-	-	-	Haemolysin XhlA
HDLMBCOA_00728	1.38e-53	-	-	-	S	-	-	-	Bacteriophage holin
HDLMBCOA_00729	0.000862	-	-	-	S	-	-	-	Glycosyl hydrolases family 25
HDLMBCOA_00731	1.01e-226	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HDLMBCOA_00732	1.78e-88	-	-	-	L	-	-	-	nuclease
HDLMBCOA_00733	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HDLMBCOA_00734	5.82e-141	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HDLMBCOA_00735	2.47e-253	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HDLMBCOA_00736	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HDLMBCOA_00737	8.42e-50	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
HDLMBCOA_00738	6.7e-141	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
HDLMBCOA_00739	7.57e-119	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HDLMBCOA_00740	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HDLMBCOA_00741	2.05e-62	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HDLMBCOA_00742	6.22e-140	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HDLMBCOA_00743	1.01e-51	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HDLMBCOA_00744	1.28e-152	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HDLMBCOA_00745	1.39e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
HDLMBCOA_00746	2.33e-239	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HDLMBCOA_00747	8.46e-77	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HDLMBCOA_00748	1.26e-211	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HDLMBCOA_00749	3.17e-191	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HDLMBCOA_00750	2.86e-245	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HDLMBCOA_00751	7.29e-268	phnW	2.6.1.37	-	E	ko:K03430	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000,ko01007	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
HDLMBCOA_00752	1.97e-187	phnX	3.11.1.1	-	E	ko:K05306	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the HAD-like hydrolase superfamily. PhnX family
HDLMBCOA_00753	3.33e-184	phnE1	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HDLMBCOA_00754	6.51e-178	phnE2	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter permease
HDLMBCOA_00755	5.4e-176	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HDLMBCOA_00756	9.91e-242	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
HDLMBCOA_00757	2.29e-165	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
HDLMBCOA_00758	4.66e-131	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
HDLMBCOA_00759	5.74e-108	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HDLMBCOA_00760	1.48e-248	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HDLMBCOA_00761	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
HDLMBCOA_00762	3.67e-154	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HDLMBCOA_00763	3.95e-139	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HDLMBCOA_00764	9.82e-55	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HDLMBCOA_00765	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HDLMBCOA_00766	0.0	ydaO	-	-	E	-	-	-	amino acid
HDLMBCOA_00767	7.29e-247	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
HDLMBCOA_00768	2.68e-198	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HDLMBCOA_00769	3.7e-149	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
HDLMBCOA_00770	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
HDLMBCOA_00771	6.92e-163	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
HDLMBCOA_00772	1.27e-129	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HDLMBCOA_00773	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HDLMBCOA_00774	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HDLMBCOA_00775	2.48e-177	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
HDLMBCOA_00776	2.64e-62	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
HDLMBCOA_00777	2.15e-209	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	L-malate dehydrogenase activity
HDLMBCOA_00778	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
HDLMBCOA_00779	2.36e-285	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HDLMBCOA_00780	8.65e-228	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
HDLMBCOA_00781	1.21e-268	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
HDLMBCOA_00782	3.95e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HDLMBCOA_00783	6.45e-111	-	-	-	-	-	-	-	-
HDLMBCOA_00784	4.86e-45	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HDLMBCOA_00785	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HDLMBCOA_00786	8.13e-239	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HDLMBCOA_00787	2.16e-39	-	-	-	-	-	-	-	-
HDLMBCOA_00788	2.08e-161	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
HDLMBCOA_00789	5.35e-220	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HDLMBCOA_00790	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HDLMBCOA_00791	1.02e-155	-	-	-	S	-	-	-	repeat protein
HDLMBCOA_00792	2.41e-157	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
HDLMBCOA_00793	0.0	-	-	-	N	-	-	-	domain, Protein
HDLMBCOA_00794	2.87e-247	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HDLMBCOA_00795	4.17e-153	-	-	-	N	-	-	-	WxL domain surface cell wall-binding
HDLMBCOA_00796	4.64e-150	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
HDLMBCOA_00797	7.83e-303	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
HDLMBCOA_00798	3.19e-285	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HDLMBCOA_00799	4.94e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
HDLMBCOA_00800	4.88e-276	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HDLMBCOA_00801	5.85e-158	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HDLMBCOA_00802	7.74e-47	-	-	-	-	-	-	-	-
HDLMBCOA_00803	3.51e-125	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HDLMBCOA_00804	5.74e-241	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HDLMBCOA_00805	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HDLMBCOA_00806	6.52e-124	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
HDLMBCOA_00807	2.06e-187	ylmH	-	-	S	-	-	-	S4 domain protein
HDLMBCOA_00808	6.45e-49	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
HDLMBCOA_00809	1.56e-93	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HDLMBCOA_00810	9.39e-295	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HDLMBCOA_00811	3.55e-312	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HDLMBCOA_00812	2.34e-208	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HDLMBCOA_00813	5e-253	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HDLMBCOA_00814	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HDLMBCOA_00815	2.81e-231	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HDLMBCOA_00816	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HDLMBCOA_00817	7.01e-76	ftsL	-	-	D	-	-	-	Cell division protein FtsL
HDLMBCOA_00818	1.74e-224	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HDLMBCOA_00819	1.35e-100	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HDLMBCOA_00820	3.22e-82	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
HDLMBCOA_00821	4.1e-223	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HDLMBCOA_00822	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HDLMBCOA_00823	1.41e-124	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HDLMBCOA_00824	2.5e-147	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HDLMBCOA_00825	3.59e-301	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HDLMBCOA_00827	1.12e-207	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
HDLMBCOA_00828	4.82e-55	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HDLMBCOA_00829	9.52e-264	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
HDLMBCOA_00830	2.68e-75	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HDLMBCOA_00831	1.6e-246	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HDLMBCOA_00832	7.21e-150	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
HDLMBCOA_00833	6.31e-222	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HDLMBCOA_00834	1.06e-192	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HDLMBCOA_00835	9.08e-157	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HDLMBCOA_00836	2.24e-148	yjbH	-	-	Q	-	-	-	Thioredoxin
HDLMBCOA_00837	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
HDLMBCOA_00838	1.3e-263	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HDLMBCOA_00839	7.12e-170	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HDLMBCOA_00840	9.28e-89	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HDLMBCOA_00841	2.81e-178	yhfI	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HDLMBCOA_00842	1.08e-117	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
HDLMBCOA_00865	1.31e-29	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDLMBCOA_00866	8.13e-90	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HDLMBCOA_00867	2.15e-07	-	-	-	K	-	-	-	transcriptional regulator
HDLMBCOA_00868	3.22e-273	-	-	-	S	-	-	-	membrane
HDLMBCOA_00869	7.46e-106	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDLMBCOA_00870	0.0	-	-	-	S	-	-	-	Zinc finger, swim domain protein
HDLMBCOA_00871	8.09e-146	-	-	-	GM	-	-	-	epimerase
HDLMBCOA_00872	6.34e-90	-	-	-	S	-	-	-	Protein of unknown function (DUF1722)
HDLMBCOA_00873	2.65e-93	spx2	-	-	P	ko:K16509	-	ko00000	ArsC family
HDLMBCOA_00874	8.13e-137	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
HDLMBCOA_00875	1.68e-176	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
HDLMBCOA_00876	0.0	nox	-	-	P	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HDLMBCOA_00877	1.3e-264	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HDLMBCOA_00878	4.38e-102	-	-	-	K	-	-	-	Transcriptional regulator
HDLMBCOA_00879	4.6e-307	-	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Major Facilitator Superfamily
HDLMBCOA_00880	8.96e-310	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HDLMBCOA_00881	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
HDLMBCOA_00882	1.02e-230	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HDLMBCOA_00883	4.8e-278	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HDLMBCOA_00884	1.93e-266	-	-	-	-	-	-	-	-
HDLMBCOA_00885	3.54e-117	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HDLMBCOA_00886	2.27e-80	-	-	-	P	-	-	-	Rhodanese Homology Domain
HDLMBCOA_00887	0.0	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HDLMBCOA_00888	2.74e-112	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HDLMBCOA_00889	2.08e-213	drrA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HDLMBCOA_00890	5.09e-165	drrB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HDLMBCOA_00891	1.75e-295	-	-	-	M	-	-	-	O-Antigen ligase
HDLMBCOA_00892	6.85e-164	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HDLMBCOA_00893	1.09e-249	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HDLMBCOA_00894	3.17e-299	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HDLMBCOA_00895	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HDLMBCOA_00897	3.36e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HDLMBCOA_00898	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HDLMBCOA_00899	8.69e-230	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HDLMBCOA_00900	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HDLMBCOA_00901	2.51e-98	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
HDLMBCOA_00902	7.94e-218	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
HDLMBCOA_00903	3.13e-211	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
HDLMBCOA_00904	3.99e-92	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HDLMBCOA_00905	7.1e-176	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HDLMBCOA_00906	1.3e-132	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HDLMBCOA_00907	2.69e-167	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HDLMBCOA_00908	2.24e-126	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HDLMBCOA_00909	1.72e-245	-	-	-	S	-	-	-	Helix-turn-helix domain
HDLMBCOA_00910	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HDLMBCOA_00911	1.25e-39	-	-	-	M	-	-	-	Lysin motif
HDLMBCOA_00912	1.27e-151	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HDLMBCOA_00913	1.98e-281	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HDLMBCOA_00914	4.84e-313	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HDLMBCOA_00915	5.57e-55	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HDLMBCOA_00916	7.1e-292	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
HDLMBCOA_00917	7.48e-192	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HDLMBCOA_00918	1.39e-185	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HDLMBCOA_00919	1.27e-291	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HDLMBCOA_00920	6.46e-109	-	-	-	-	-	-	-	-
HDLMBCOA_00921	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HDLMBCOA_00922	4.04e-242	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HDLMBCOA_00923	1.8e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HDLMBCOA_00924	2.03e-189	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
HDLMBCOA_00925	5.66e-207	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HDLMBCOA_00926	3.29e-147	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
HDLMBCOA_00927	9.33e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HDLMBCOA_00928	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HDLMBCOA_00929	1.74e-313	qacA	-	-	EGP	-	-	-	Major Facilitator
HDLMBCOA_00930	5.52e-64	-	-	-	U	-	-	-	nuclease activity
HDLMBCOA_00931	8.53e-28	-	-	-	-	-	-	-	-
HDLMBCOA_00932	1.3e-49	-	-	-	-	-	-	-	-
HDLMBCOA_00933	5.89e-131	-	-	-	S	-	-	-	ankyrin repeats
HDLMBCOA_00934	1.24e-11	-	-	-	S	-	-	-	Immunity protein 22
HDLMBCOA_00935	5.01e-226	-	-	-	-	-	-	-	-
HDLMBCOA_00936	1.82e-34	-	-	-	S	-	-	-	Immunity protein 74
HDLMBCOA_00937	2.67e-89	-	-	-	M	-	-	-	dTDP-4-dehydrorhamnose reductase activity
HDLMBCOA_00938	0.0	-	-	-	M	-	-	-	domain protein
HDLMBCOA_00939	2.14e-174	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HDLMBCOA_00940	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
HDLMBCOA_00941	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HDLMBCOA_00942	0.0	gshR	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HDLMBCOA_00943	2.7e-230	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HDLMBCOA_00944	0.0	proWX	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HDLMBCOA_00945	4.06e-102	-	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA-DNA hybrid ribonuclease activity
HDLMBCOA_00946	2.42e-207	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HDLMBCOA_00947	1.49e-223	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
HDLMBCOA_00948	3.45e-103	accB3	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HDLMBCOA_00949	2.16e-103	-	-	-	-	-	-	-	-
HDLMBCOA_00950	5.89e-108	-	-	-	K	-	-	-	Winged helix-turn-helix transcription repressor, HrcA DNA-binding
HDLMBCOA_00951	1.96e-295	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HDLMBCOA_00952	5.33e-124	yxkA	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HDLMBCOA_00953	1.08e-71	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
HDLMBCOA_00954	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
HDLMBCOA_00955	1.02e-154	rpiA2	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HDLMBCOA_00956	1.22e-131	zmp1	-	-	O	-	-	-	Zinc-dependent metalloprotease
HDLMBCOA_00957	8.95e-60	-	-	-	-	-	-	-	-
HDLMBCOA_00958	1.09e-227	hicD1	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HDLMBCOA_00959	3.5e-307	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
HDLMBCOA_00960	0.0	-	-	-	P	-	-	-	Major Facilitator Superfamily
HDLMBCOA_00961	2.39e-121	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HDLMBCOA_00962	3.78e-57	-	-	-	-	-	-	-	-
HDLMBCOA_00963	9.42e-258	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HDLMBCOA_00964	1.64e-198	tagG	-	-	U	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
HDLMBCOA_00965	1.13e-273	-	-	-	-	-	-	-	-
HDLMBCOA_00966	9.17e-286	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HDLMBCOA_00967	2.21e-133	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HDLMBCOA_00968	9.4e-11	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HDLMBCOA_00969	4.45e-116	metP_2	-	-	U	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HDLMBCOA_00970	1.13e-157	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HDLMBCOA_00971	1.06e-143	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
HDLMBCOA_00972	1.1e-78	-	-	-	S	-	-	-	CHY zinc finger
HDLMBCOA_00973	1.18e-224	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HDLMBCOA_00974	2.18e-123	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HDLMBCOA_00975	6.4e-54	-	-	-	-	-	-	-	-
HDLMBCOA_00976	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HDLMBCOA_00977	7.28e-42	-	-	-	-	-	-	-	-
HDLMBCOA_00978	4.09e-170	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
HDLMBCOA_00979	4.76e-305	xylP1	-	-	G	-	-	-	MFS/sugar transport protein
HDLMBCOA_00982	8.16e-207	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
HDLMBCOA_00983	0.0	acdH	1.1.1.1, 1.2.1.10, 1.2.1.87	-	C	ko:K04072,ko:K13922	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
HDLMBCOA_00984	1.08e-243	-	-	-	-	-	-	-	-
HDLMBCOA_00985	1.85e-208	-	-	-	V	ko:K01990,ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HDLMBCOA_00986	3.59e-78	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HDLMBCOA_00987	2.06e-30	-	-	-	-	-	-	-	-
HDLMBCOA_00988	2.14e-117	-	-	-	K	-	-	-	acetyltransferase
HDLMBCOA_00989	1.88e-111	-	-	-	K	-	-	-	GNAT family
HDLMBCOA_00990	8.08e-110	-	-	-	S	-	-	-	ASCH
HDLMBCOA_00991	3.68e-125	-	-	-	K	-	-	-	Cupin domain
HDLMBCOA_00992	8.8e-264	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HDLMBCOA_00993	3.14e-190	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HDLMBCOA_00994	5.58e-181	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HDLMBCOA_00995	5.3e-265	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HDLMBCOA_00996	6.25e-53	-	-	-	-	-	-	-	-
HDLMBCOA_00997	9.59e-288	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HDLMBCOA_00998	1.24e-99	-	-	-	K	-	-	-	Transcriptional regulator
HDLMBCOA_00999	1.48e-99	-	-	-	S	ko:K02348	-	ko00000	GNAT family
HDLMBCOA_01000	9.17e-285	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HDLMBCOA_01001	2.03e-75	-	-	-	-	-	-	-	-
HDLMBCOA_01002	0.0	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
HDLMBCOA_01003	1.14e-168	-	-	-	-	-	-	-	-
HDLMBCOA_01004	4.29e-227	-	-	-	-	-	-	-	-
HDLMBCOA_01005	4.2e-88	gcsH1	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Glycine cleavage H-protein
HDLMBCOA_01006	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HDLMBCOA_01007	1.38e-155	csrR	-	-	K	-	-	-	response regulator
HDLMBCOA_01008	3.12e-311	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HDLMBCOA_01009	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HDLMBCOA_01010	1.09e-223	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HDLMBCOA_01011	3.06e-124	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HDLMBCOA_01012	3.66e-127	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HDLMBCOA_01013	3.04e-280	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HDLMBCOA_01014	3.3e-180	yqeM	-	-	Q	-	-	-	Methyltransferase
HDLMBCOA_01015	1.06e-76	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HDLMBCOA_01016	1.71e-149	yqeK	-	-	H	-	-	-	Hydrolase, HD family
HDLMBCOA_01017	4.19e-153	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HDLMBCOA_01018	2.19e-67	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
HDLMBCOA_01019	3.81e-276	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
HDLMBCOA_01020	5.7e-127	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
HDLMBCOA_01021	8.95e-18	-	-	-	-	-	-	-	-
HDLMBCOA_01022	2.66e-315	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
HDLMBCOA_01023	2.39e-175	racD	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HDLMBCOA_01024	1.64e-83	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HDLMBCOA_01025	1.18e-250	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HDLMBCOA_01026	7.03e-307	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
HDLMBCOA_01027	5.37e-72	-	-	-	-	-	-	-	-
HDLMBCOA_01028	6.88e-73	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HDLMBCOA_01029	6.92e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HDLMBCOA_01030	2.37e-109	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HDLMBCOA_01031	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HDLMBCOA_01032	3.5e-220	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HDLMBCOA_01033	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
HDLMBCOA_01034	1.58e-117	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HDLMBCOA_01035	1.11e-132	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HDLMBCOA_01036	3.19e-202	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HDLMBCOA_01037	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HDLMBCOA_01038	8.51e-155	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HDLMBCOA_01039	2.1e-141	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HDLMBCOA_01040	4.07e-60	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HDLMBCOA_01041	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
HDLMBCOA_01042	2.71e-108	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
HDLMBCOA_01043	3.17e-299	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HDLMBCOA_01044	1.49e-310	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
HDLMBCOA_01045	1.1e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
HDLMBCOA_01046	2.87e-47	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
HDLMBCOA_01047	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HDLMBCOA_01048	3.04e-29	-	-	-	S	-	-	-	Virus attachment protein p12 family
HDLMBCOA_01049	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HDLMBCOA_01050	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HDLMBCOA_01051	1.29e-148	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HDLMBCOA_01052	2.94e-71	ytzB	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HDLMBCOA_01053	4.7e-156	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HDLMBCOA_01054	7.24e-197	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
HDLMBCOA_01055	8.17e-285	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HDLMBCOA_01056	1.1e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDLMBCOA_01057	3.6e-106	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
HDLMBCOA_01058	6.76e-73	-	-	-	-	-	-	-	-
HDLMBCOA_01059	1.09e-196	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HDLMBCOA_01060	2.93e-152	draG	-	-	O	-	-	-	ADP-ribosylglycohydrolase
HDLMBCOA_01061	5.76e-135	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HDLMBCOA_01062	2.82e-138	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HDLMBCOA_01063	9.64e-248	-	-	-	S	-	-	-	Fn3-like domain
HDLMBCOA_01064	1.65e-80	-	-	-	-	-	-	-	-
HDLMBCOA_01065	0.0	-	-	-	-	-	-	-	-
HDLMBCOA_01066	5.19e-309	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
HDLMBCOA_01067	4.89e-146	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDLMBCOA_01068	3.3e-151	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
HDLMBCOA_01070	3.69e-277	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HDLMBCOA_01071	3.98e-169	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HDLMBCOA_01072	1.23e-200	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HDLMBCOA_01073	4.75e-267	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HDLMBCOA_01074	1.79e-272	pbpX	-	-	V	-	-	-	Beta-lactamase
HDLMBCOA_01075	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HDLMBCOA_01076	2.9e-139	-	-	-	-	-	-	-	-
HDLMBCOA_01077	7.62e-97	-	-	-	-	-	-	-	-
HDLMBCOA_01079	1.12e-209	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HDLMBCOA_01080	2.22e-313	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDLMBCOA_01081	3.93e-99	-	-	-	T	-	-	-	Universal stress protein family
HDLMBCOA_01083	5.62e-316	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
HDLMBCOA_01084	1.94e-245	mocA	-	-	S	-	-	-	Oxidoreductase
HDLMBCOA_01085	6.22e-43	cspP	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
HDLMBCOA_01086	7.34e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
HDLMBCOA_01087	1.67e-177	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HDLMBCOA_01088	9.33e-195	gntR	-	-	K	-	-	-	rpiR family
HDLMBCOA_01089	1.94e-213	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HDLMBCOA_01090	1.66e-305	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDLMBCOA_01091	0.0	yfgQ	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
HDLMBCOA_01092	5.56e-130	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDLMBCOA_01093	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HDLMBCOA_01094	1.59e-242	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
HDLMBCOA_01095	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HDLMBCOA_01096	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HDLMBCOA_01097	5.11e-67	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HDLMBCOA_01098	2.23e-261	camS	-	-	S	-	-	-	sex pheromone
HDLMBCOA_01099	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HDLMBCOA_01100	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HDLMBCOA_01101	1.98e-279	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HDLMBCOA_01102	1.13e-120	yebE	-	-	S	-	-	-	UPF0316 protein
HDLMBCOA_01103	8.19e-134	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HDLMBCOA_01104	3.41e-146	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
HDLMBCOA_01105	3.86e-235	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HDLMBCOA_01106	9.92e-212	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HDLMBCOA_01107	4.87e-234	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HDLMBCOA_01108	1.89e-208	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HDLMBCOA_01109	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HDLMBCOA_01110	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HDLMBCOA_01111	7.76e-234	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
HDLMBCOA_01112	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
HDLMBCOA_01113	0.0	-	-	-	S	ko:K06889	-	ko00000	Alpha beta
HDLMBCOA_01114	3.52e-32	-	-	-	-	-	-	-	-
HDLMBCOA_01115	4.37e-128	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HDLMBCOA_01116	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
HDLMBCOA_01117	2.6e-212	mleP2	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
HDLMBCOA_01118	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
HDLMBCOA_01119	6.5e-215	mleR	-	-	K	-	-	-	LysR family
HDLMBCOA_01120	3.06e-205	mleR2	-	-	K	-	-	-	LysR family transcriptional regulator
HDLMBCOA_01121	1.98e-122	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HDLMBCOA_01122	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HDLMBCOA_01123	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HDLMBCOA_01127	5.21e-65	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
HDLMBCOA_01128	1.38e-71	-	-	-	S	-	-	-	Cupin domain
HDLMBCOA_01129	1.31e-213	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
HDLMBCOA_01130	1.86e-246	ysdE	-	-	P	-	-	-	Citrate transporter
HDLMBCOA_01131	1.06e-195	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HDLMBCOA_01132	5.35e-175	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HDLMBCOA_01133	2.4e-279	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HDLMBCOA_01134	5.41e-160	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HDLMBCOA_01135	3.99e-177	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HDLMBCOA_01136	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HDLMBCOA_01137	5.27e-197	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HDLMBCOA_01138	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HDLMBCOA_01139	6.3e-95	-	-	-	-	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	-
HDLMBCOA_01140	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
HDLMBCOA_01141	5.34e-107	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HDLMBCOA_01142	1.71e-302	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HDLMBCOA_01143	8.77e-204	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HDLMBCOA_01145	2.27e-197	-	-	-	G	-	-	-	Peptidase_C39 like family
HDLMBCOA_01146	2.63e-217	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HDLMBCOA_01147	2.43e-174	manM	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
HDLMBCOA_01148	8.89e-218	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
HDLMBCOA_01149	9.05e-85	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
HDLMBCOA_01150	0.0	levR	-	-	K	-	-	-	Sigma-54 interaction domain
HDLMBCOA_01151	1.19e-92	levD	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11194	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HDLMBCOA_01152	2.14e-111	manX	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HDLMBCOA_01153	3.15e-229	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HDLMBCOA_01154	9.24e-85	accB1	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin-requiring enzyme
HDLMBCOA_01155	1.7e-315	accC1	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase C-terminal domain
HDLMBCOA_01156	1.05e-183	accD1	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HDLMBCOA_01157	1.01e-176	accA1	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
HDLMBCOA_01158	2.29e-234	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HDLMBCOA_01159	7.53e-215	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
HDLMBCOA_01160	8.57e-227	-	-	-	EG	-	-	-	EamA-like transporter family
HDLMBCOA_01161	1.91e-165	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HDLMBCOA_01162	7.87e-158	zmp2	-	-	O	-	-	-	Zinc-dependent metalloprotease
HDLMBCOA_01163	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HDLMBCOA_01164	1.62e-158	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HDLMBCOA_01165	5.96e-69	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
HDLMBCOA_01166	9.43e-127	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
HDLMBCOA_01167	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HDLMBCOA_01168	4.91e-265	yacL	-	-	S	-	-	-	domain protein
HDLMBCOA_01169	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HDLMBCOA_01170	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HDLMBCOA_01171	1.35e-92	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HDLMBCOA_01172	1.49e-177	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HDLMBCOA_01173	3.4e-126	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
HDLMBCOA_01174	1.12e-130	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Sigma-70 region 2
HDLMBCOA_01175	4.55e-31	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HDLMBCOA_01176	1e-39	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HDLMBCOA_01177	1.89e-128	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HDLMBCOA_01178	2.81e-202	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HDLMBCOA_01179	3.98e-92	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HDLMBCOA_01180	2.69e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HDLMBCOA_01181	3.72e-105	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HDLMBCOA_01182	2.76e-74	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HDLMBCOA_01184	1.33e-294	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HDLMBCOA_01188	4.23e-19	-	-	-	S	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HDLMBCOA_01191	2.08e-22	-	-	-	K	ko:K22299	-	ko00000,ko03000	sequence-specific DNA binding
HDLMBCOA_01192	4.29e-05	-	-	-	K	-	-	-	PFAM helix-turn-helix domain protein
HDLMBCOA_01196	3.54e-43	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
HDLMBCOA_01198	6.53e-121	-	-	-	-	-	-	-	-
HDLMBCOA_01201	1.47e-128	-	-	-	S	-	-	-	Protein of unknown function (DUF1361)
HDLMBCOA_01202	3.07e-119	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HDLMBCOA_01203	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HDLMBCOA_01204	6.24e-214	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HDLMBCOA_01205	3.09e-213	ysjB	-	-	S	ko:K03810	-	ko00000	Oxidoreductase family, NAD-binding Rossmann fold
HDLMBCOA_01206	2.53e-198	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HDLMBCOA_01207	9.81e-129	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HDLMBCOA_01208	2.52e-114	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HDLMBCOA_01209	1.29e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
HDLMBCOA_01210	1.43e-226	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
HDLMBCOA_01211	1.4e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HDLMBCOA_01212	1.98e-199	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HDLMBCOA_01213	2.29e-136	-	-	-	-	-	-	-	-
HDLMBCOA_01214	9.36e-171	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HDLMBCOA_01215	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HDLMBCOA_01216	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HDLMBCOA_01217	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HDLMBCOA_01218	2.4e-107	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HDLMBCOA_01219	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HDLMBCOA_01220	3.83e-179	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
HDLMBCOA_01221	1.76e-43	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HDLMBCOA_01222	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HDLMBCOA_01223	2.83e-168	-	-	-	-	-	-	-	-
HDLMBCOA_01224	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HDLMBCOA_01225	7.15e-179	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HDLMBCOA_01226	1.31e-285	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HDLMBCOA_01227	2.02e-245	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HDLMBCOA_01228	5.75e-242	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
HDLMBCOA_01229	1.14e-311	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	Sigma-54 factor, core binding domain
HDLMBCOA_01231	5.11e-133	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HDLMBCOA_01232	5.18e-224	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HDLMBCOA_01233	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HDLMBCOA_01234	1.21e-215	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HDLMBCOA_01235	5.32e-242	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HDLMBCOA_01236	1.71e-207	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HDLMBCOA_01237	7.09e-113	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HDLMBCOA_01238	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HDLMBCOA_01239	7.5e-302	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HDLMBCOA_01240	2.21e-113	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HDLMBCOA_01241	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HDLMBCOA_01242	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HDLMBCOA_01243	9.45e-152	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
HDLMBCOA_01244	4.38e-267	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
HDLMBCOA_01245	4.63e-135	aad	3.4.13.22	-	E	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HDLMBCOA_01246	0.0	nox2	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HDLMBCOA_01247	5.9e-170	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HDLMBCOA_01248	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HDLMBCOA_01249	5.01e-58	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
HDLMBCOA_01250	4.31e-141	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
HDLMBCOA_01251	8.65e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HDLMBCOA_01252	2.49e-203	nox	-	-	C	-	-	-	NADH oxidase
HDLMBCOA_01253	1.27e-181	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HDLMBCOA_01254	2.74e-202	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
HDLMBCOA_01255	7.54e-211	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HDLMBCOA_01256	5.78e-268	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HDLMBCOA_01257	7.42e-125	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Bacterial transferase hexapeptide (six repeats)
HDLMBCOA_01258	1.82e-126	-	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
HDLMBCOA_01259	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
HDLMBCOA_01260	1.2e-106	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
HDLMBCOA_01261	2.45e-89	-	-	-	-	-	-	-	-
HDLMBCOA_01262	1.01e-124	-	-	-	-	-	-	-	-
HDLMBCOA_01263	4.93e-42	-	-	-	-	-	-	-	-
HDLMBCOA_01264	4.81e-76	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HDLMBCOA_01265	2.43e-111	-	-	-	-	-	-	-	-
HDLMBCOA_01266	1.06e-281	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
HDLMBCOA_01267	5.33e-103	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDLMBCOA_01268	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
HDLMBCOA_01269	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HDLMBCOA_01270	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HDLMBCOA_01272	3.16e-170	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HDLMBCOA_01273	2.32e-43	ygzD	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional
HDLMBCOA_01274	1.2e-91	-	-	-	-	-	-	-	-
HDLMBCOA_01275	1.28e-102	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HDLMBCOA_01276	5.3e-202	dkgB	-	-	S	-	-	-	reductase
HDLMBCOA_01277	6.07e-117	gpo	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
HDLMBCOA_01278	4.77e-130	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC transporter permease
HDLMBCOA_01279	0.0	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HDLMBCOA_01280	2.13e-150	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
HDLMBCOA_01281	4.65e-192	-	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
HDLMBCOA_01282	2.37e-93	-	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
HDLMBCOA_01283	5.66e-74	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HDLMBCOA_01284	3.18e-77	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HDLMBCOA_01285	3.81e-18	-	-	-	-	-	-	-	-
HDLMBCOA_01286	1.29e-278	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HDLMBCOA_01287	1.53e-208	fbpA	-	-	K	-	-	-	Domain of unknown function (DUF814)
HDLMBCOA_01288	1.35e-78	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
HDLMBCOA_01289	6.33e-46	-	-	-	-	-	-	-	-
HDLMBCOA_01290	2.49e-229	yghZ	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
HDLMBCOA_01291	1.11e-146	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
HDLMBCOA_01292	2.51e-259	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HDLMBCOA_01293	1.19e-277	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HDLMBCOA_01294	1.31e-102	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HDLMBCOA_01295	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HDLMBCOA_01296	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HDLMBCOA_01297	1.2e-200	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HDLMBCOA_01299	0.0	-	-	-	M	-	-	-	domain protein
HDLMBCOA_01300	5.15e-247	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
HDLMBCOA_01301	6.79e-203	mleR	-	-	K	-	-	-	LysR substrate binding domain
HDLMBCOA_01302	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HDLMBCOA_01303	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HDLMBCOA_01304	1.92e-209	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HDLMBCOA_01305	0.0	-	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HDLMBCOA_01306	2.4e-230	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
HDLMBCOA_01307	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HDLMBCOA_01308	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HDLMBCOA_01309	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HDLMBCOA_01310	1.54e-216	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HDLMBCOA_01311	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	Alanine-glyoxylate amino-transferase
HDLMBCOA_01312	1.65e-46	dltC2	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDLMBCOA_01313	1.72e-148	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HDLMBCOA_01314	7.06e-271	-	-	-	EGP	ko:K08218	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Major facilitator Superfamily
HDLMBCOA_01315	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HDLMBCOA_01316	4.16e-285	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDLMBCOA_01317	4.9e-64	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HDLMBCOA_01318	2.37e-68	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HDLMBCOA_01319	1.34e-104	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HDLMBCOA_01320	0.0	celR	-	-	K	-	-	-	PRD domain
HDLMBCOA_01321	6.25e-138	-	-	-	-	-	-	-	-
HDLMBCOA_01322	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HDLMBCOA_01323	4.64e-106	-	-	-	-	-	-	-	-
HDLMBCOA_01324	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HDLMBCOA_01325	8.2e-102	yybD	-	-	S	ko:K02348	-	ko00000	Acetyltransferase (GNAT) domain
HDLMBCOA_01328	1.79e-42	-	-	-	-	-	-	-	-
HDLMBCOA_01329	2.69e-316	dinF	-	-	V	-	-	-	MatE
HDLMBCOA_01330	0.0	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
HDLMBCOA_01331	0.0	astA	2.8.2.22	-	M	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
HDLMBCOA_01332	2.54e-225	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
HDLMBCOA_01333	3.72e-145	cysC	2.7.1.25	-	F	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
HDLMBCOA_01334	7.32e-292	sat	2.7.7.4	-	H	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
HDLMBCOA_01335	0.0	-	-	-	S	-	-	-	Protein conserved in bacteria
HDLMBCOA_01336	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HDLMBCOA_01337	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HDLMBCOA_01338	8.01e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1516)
HDLMBCOA_01339	4.91e-117	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
HDLMBCOA_01340	5.53e-237	-	-	-	-	-	-	-	-
HDLMBCOA_01341	9.03e-16	-	-	-	-	-	-	-	-
HDLMBCOA_01342	4.29e-87	-	-	-	-	-	-	-	-
HDLMBCOA_01344	9.83e-137	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HDLMBCOA_01345	1.78e-07	-	-	-	S	-	-	-	Bacteriophage A118-like holin, Hol118
HDLMBCOA_01347	4.34e-55	-	-	-	-	-	-	-	-
HDLMBCOA_01349	9.57e-26	-	-	-	S	-	-	-	Protein of unknown function (DUF1617)
HDLMBCOA_01350	1.3e-99	-	-	-	L	-	-	-	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HDLMBCOA_01352	1.13e-193	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
HDLMBCOA_01354	5.36e-44	-	-	-	S	-	-	-	Phage tail tube protein
HDLMBCOA_01355	4.57e-29	-	-	-	-	-	-	-	-
HDLMBCOA_01356	1.12e-32	-	-	-	-	-	-	-	-
HDLMBCOA_01357	4.31e-32	-	-	-	-	-	-	-	-
HDLMBCOA_01358	6.56e-19	-	-	-	-	-	-	-	-
HDLMBCOA_01359	2.12e-133	-	-	-	S	-	-	-	Phage capsid family
HDLMBCOA_01360	5.29e-74	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Clp protease
HDLMBCOA_01361	1.76e-128	-	-	-	S	-	-	-	Phage portal protein
HDLMBCOA_01362	5.85e-214	-	-	-	S	-	-	-	Terminase
HDLMBCOA_01363	4.24e-14	-	-	-	-	-	-	-	-
HDLMBCOA_01366	1.96e-31	-	-	-	V	-	-	-	HNH nucleases
HDLMBCOA_01368	7.45e-216	-	-	-	-	-	-	-	-
HDLMBCOA_01369	5.42e-150	dpnM	2.1.1.72	-	H	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	Site-specific DNA-methyltransferase (adenine-specific)
HDLMBCOA_01370	5.29e-211	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HDLMBCOA_01371	1.3e-110	queT	-	-	S	-	-	-	QueT transporter
HDLMBCOA_01372	2.63e-241	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HDLMBCOA_01373	1.82e-275	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine
HDLMBCOA_01374	2.36e-166	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
HDLMBCOA_01375	1.13e-292	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HDLMBCOA_01376	3.61e-244	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HDLMBCOA_01377	2.14e-259	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HDLMBCOA_01378	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HDLMBCOA_01379	2.02e-171	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HDLMBCOA_01380	1.13e-135	-	-	-	U	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HDLMBCOA_01381	4.73e-57	-	-	-	U	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HDLMBCOA_01382	1.37e-248	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	ABC transporter, substratebinding protein
HDLMBCOA_01383	9.07e-219	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HDLMBCOA_01384	3.26e-222	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HDLMBCOA_01385	2.58e-85	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HDLMBCOA_01386	5e-275	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HDLMBCOA_01387	9.32e-81	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HDLMBCOA_01388	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HDLMBCOA_01389	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HDLMBCOA_01390	1.84e-189	-	-	-	-	-	-	-	-
HDLMBCOA_01391	1.78e-191	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HDLMBCOA_01392	5.35e-121	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HDLMBCOA_01393	3.14e-164	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
HDLMBCOA_01394	8.61e-273	-	-	-	J	-	-	-	translation release factor activity
HDLMBCOA_01395	1.91e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HDLMBCOA_01396	6.26e-306	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HDLMBCOA_01397	2.08e-302	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HDLMBCOA_01398	4.01e-36	-	-	-	-	-	-	-	-
HDLMBCOA_01399	6.59e-170	-	-	-	S	-	-	-	YheO-like PAS domain
HDLMBCOA_01400	2.31e-201	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HDLMBCOA_01401	7.51e-159	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
HDLMBCOA_01402	4.6e-290	sdaC	-	-	E	ko:K03837	-	ko00000,ko02000	amino acid
HDLMBCOA_01403	8.29e-312	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HDLMBCOA_01404	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HDLMBCOA_01405	2.96e-89	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HDLMBCOA_01406	2.87e-101	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
HDLMBCOA_01407	8.6e-198	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
HDLMBCOA_01408	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
HDLMBCOA_01409	1.45e-191	yxeH	-	-	S	-	-	-	hydrolase
HDLMBCOA_01410	1.01e-177	-	-	-	-	-	-	-	-
HDLMBCOA_01411	2.82e-236	-	-	-	S	-	-	-	DUF218 domain
HDLMBCOA_01412	3.26e-228	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HDLMBCOA_01413	9.06e-193	bla1	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HDLMBCOA_01414	5.78e-292	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HDLMBCOA_01415	1.96e-189	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HDLMBCOA_01416	5.3e-49	-	-	-	-	-	-	-	-
HDLMBCOA_01417	2.95e-57	-	-	-	S	-	-	-	ankyrin repeats
HDLMBCOA_01419	2.07e-144	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
HDLMBCOA_01420	2.31e-132	thgA3	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
HDLMBCOA_01421	2.49e-167	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HDLMBCOA_01422	8.81e-205	-	-	-	S	-	-	-	Alpha beta hydrolase
HDLMBCOA_01423	1.39e-143	-	-	-	GM	-	-	-	NmrA-like family
HDLMBCOA_01424	1.74e-101	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2255)
HDLMBCOA_01425	5.72e-207	-	-	-	K	-	-	-	Transcriptional regulator
HDLMBCOA_01426	3.78e-221	cryZ	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HDLMBCOA_01428	2.12e-62	nox4	-	-	C	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HDLMBCOA_01429	3.44e-264	nox4	-	-	C	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HDLMBCOA_01430	1.51e-132	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
HDLMBCOA_01431	1.03e-265	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HDLMBCOA_01432	1.27e-174	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HDLMBCOA_01433	8.42e-204	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HDLMBCOA_01435	6.64e-109	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HDLMBCOA_01436	5.53e-94	-	-	-	K	-	-	-	MarR family
HDLMBCOA_01437	1.28e-148	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HDLMBCOA_01438	0.000138	yjdF	-	-	S	-	-	-	Protein of unknown function (DUF2992)
HDLMBCOA_01439	4.36e-208	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDLMBCOA_01440	3.35e-167	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HDLMBCOA_01441	6.08e-253	-	-	-	-	-	-	-	-
HDLMBCOA_01442	1.06e-255	-	-	-	-	-	-	-	-
HDLMBCOA_01443	4.94e-213	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDLMBCOA_01444	1.18e-85	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HDLMBCOA_01445	1.74e-251	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HDLMBCOA_01446	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HDLMBCOA_01447	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HDLMBCOA_01448	8.64e-224	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HDLMBCOA_01449	2.84e-189	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HDLMBCOA_01450	7.92e-217	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HDLMBCOA_01451	1.15e-94	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
HDLMBCOA_01452	7.7e-110	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HDLMBCOA_01453	4.81e-229	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
HDLMBCOA_01454	9.21e-94	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
HDLMBCOA_01455	1.09e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HDLMBCOA_01456	2.32e-194	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HDLMBCOA_01457	1e-163	-	-	-	C	-	-	-	Enoyl-(Acyl carrier protein) reductase
HDLMBCOA_01458	1.42e-217	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HDLMBCOA_01459	1.84e-284	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HDLMBCOA_01460	4.35e-204	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HDLMBCOA_01461	2.61e-132	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HDLMBCOA_01462	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HDLMBCOA_01463	2.47e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HDLMBCOA_01464	4.01e-200	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
HDLMBCOA_01465	1.47e-210	-	-	-	G	-	-	-	Fructosamine kinase
HDLMBCOA_01466	2.43e-150	yjcF	-	-	J	-	-	-	HAD-hyrolase-like
HDLMBCOA_01467	8.2e-102	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HDLMBCOA_01468	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HDLMBCOA_01469	2.56e-76	-	-	-	-	-	-	-	-
HDLMBCOA_01470	3.13e-172	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HDLMBCOA_01471	2.04e-226	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
HDLMBCOA_01472	5.28e-146	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HDLMBCOA_01473	4.78e-65	-	-	-	-	-	-	-	-
HDLMBCOA_01474	1.73e-67	-	-	-	-	-	-	-	-
HDLMBCOA_01476	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
HDLMBCOA_01477	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HDLMBCOA_01478	3e-98	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HDLMBCOA_01479	0.0	-	-	-	M	-	-	-	domain protein
HDLMBCOA_01480	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
HDLMBCOA_01481	3.4e-53	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HDLMBCOA_01482	1.27e-73	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HDLMBCOA_01483	1.45e-46	-	-	-	-	-	-	-	-
HDLMBCOA_01484	9.88e-239	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HDLMBCOA_01485	1.69e-255	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HDLMBCOA_01486	4.54e-126	-	-	-	J	-	-	-	glyoxalase III activity
HDLMBCOA_01487	2.49e-190	-	-	-	GM	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HDLMBCOA_01488	4.73e-118	rmeB	-	-	K	-	-	-	transcriptional regulator, MerR family
HDLMBCOA_01489	6.7e-74	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
HDLMBCOA_01490	7.28e-213	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HDLMBCOA_01491	3.72e-283	ysaA	-	-	V	-	-	-	RDD family
HDLMBCOA_01492	3.2e-208	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphate phosphatase, HisJ
HDLMBCOA_01493	1.48e-271	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HDLMBCOA_01494	1.69e-151	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HDLMBCOA_01495	1.92e-299	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HDLMBCOA_01496	2.46e-139	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
HDLMBCOA_01497	2.23e-142	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HDLMBCOA_01498	6.84e-166	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HDLMBCOA_01499	1.27e-172	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HDLMBCOA_01500	6.12e-78	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HDLMBCOA_01501	1.07e-68	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
HDLMBCOA_01502	4.48e-257	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HDLMBCOA_01503	4.99e-125	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HDLMBCOA_01504	1.01e-176	yceF	-	-	P	ko:K05794	-	ko00000	membrane
HDLMBCOA_01505	9.51e-203	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
HDLMBCOA_01506	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
HDLMBCOA_01507	1.32e-178	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDLMBCOA_01508	7.03e-195	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HDLMBCOA_01509	1.61e-225	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HDLMBCOA_01510	1.53e-213	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
HDLMBCOA_01511	6.08e-312	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
HDLMBCOA_01512	1.51e-285	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
HDLMBCOA_01513	3.45e-209	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HDLMBCOA_01514	4.37e-241	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HDLMBCOA_01515	5.01e-199	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HDLMBCOA_01516	1.07e-227	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HDLMBCOA_01517	9.2e-62	-	-	-	-	-	-	-	-
HDLMBCOA_01518	3.9e-105	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HDLMBCOA_01519	9.24e-140	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
HDLMBCOA_01520	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HDLMBCOA_01521	1.31e-260	-	-	-	T	-	-	-	diguanylate cyclase
HDLMBCOA_01522	4.54e-54	-	-	-	-	-	-	-	-
HDLMBCOA_01524	8.83e-317	-	-	-	EGP	-	-	-	Major Facilitator
HDLMBCOA_01525	5.61e-216	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HDLMBCOA_01526	4.08e-107	cvpA	-	-	S	-	-	-	Colicin V production protein
HDLMBCOA_01527	9.61e-84	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HDLMBCOA_01528	1.59e-121	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HDLMBCOA_01529	1.04e-133	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
HDLMBCOA_01530	5.91e-314	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HDLMBCOA_01531	5.95e-129	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
HDLMBCOA_01532	1.37e-271	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
HDLMBCOA_01533	3.91e-124	tag2	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HDLMBCOA_01534	8.03e-28	-	-	-	-	-	-	-	-
HDLMBCOA_01536	6.62e-133	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HDLMBCOA_01537	1.3e-207	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
HDLMBCOA_01538	7.27e-73	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
HDLMBCOA_01539	2.94e-149	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
HDLMBCOA_01540	1.97e-60	qacH	-	-	U	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
HDLMBCOA_01541	1.15e-77	-	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
HDLMBCOA_01542	1.68e-276	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
HDLMBCOA_01543	1.54e-228	ydbI	-	-	K	-	-	-	AI-2E family transporter
HDLMBCOA_01544	1.07e-211	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HDLMBCOA_01545	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HDLMBCOA_01547	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	C-terminus of AA_permease
HDLMBCOA_01548	4.62e-107	-	-	-	-	-	-	-	-
HDLMBCOA_01550	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HDLMBCOA_01551	4.85e-186	ptp2	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HDLMBCOA_01552	0.0	amiA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HDLMBCOA_01553	3.95e-190	amiC	-	-	U	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HDLMBCOA_01554	1.1e-109	amiC	-	-	U	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HDLMBCOA_01555	6.22e-201	-	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HDLMBCOA_01556	1.84e-241	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HDLMBCOA_01557	4.47e-181	amiF	-	-	E	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
HDLMBCOA_01558	4.17e-235	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HDLMBCOA_01559	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HDLMBCOA_01560	3.66e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HDLMBCOA_01561	2.05e-72	-	-	-	S	-	-	-	Enterocin A Immunity
HDLMBCOA_01562	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HDLMBCOA_01563	1.01e-251	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HDLMBCOA_01564	7.77e-234	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
HDLMBCOA_01565	7.84e-208	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Squalene/phytoene synthase
HDLMBCOA_01566	0.0	-	1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31	-	Q	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	ko00000,ko00001,ko01000	Flavin containing amine oxidoreductase
HDLMBCOA_01567	1.48e-152	yugP	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
HDLMBCOA_01568	1.03e-34	-	-	-	-	-	-	-	-
HDLMBCOA_01569	3.84e-186	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
HDLMBCOA_01570	5.82e-164	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
HDLMBCOA_01571	9.76e-83	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
HDLMBCOA_01572	3.18e-308	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
HDLMBCOA_01573	2.41e-84	-	-	-	S	-	-	-	Protein of unknown function (DUF1398)
HDLMBCOA_01574	2.55e-65	-	-	-	-	-	-	-	-
HDLMBCOA_01575	7.21e-35	-	-	-	-	-	-	-	-
HDLMBCOA_01576	8.8e-315	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
HDLMBCOA_01577	3.43e-96	-	-	-	S	-	-	-	COG NOG18757 non supervised orthologous group
HDLMBCOA_01578	4.26e-54	-	-	-	-	-	-	-	-
HDLMBCOA_01579	1.33e-95	copR	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
HDLMBCOA_01580	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HDLMBCOA_01581	4.38e-243	pva2	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
HDLMBCOA_01582	1.47e-144	-	-	-	S	-	-	-	VIT family
HDLMBCOA_01583	2.66e-155	-	-	-	S	-	-	-	membrane
HDLMBCOA_01584	9.43e-203	-	-	-	EG	-	-	-	EamA-like transporter family
HDLMBCOA_01585	2.52e-107	-	-	-	S	ko:K02348	-	ko00000	GNAT family
HDLMBCOA_01586	3.57e-150	-	-	-	GM	-	-	-	NmrA-like family
HDLMBCOA_01587	4.79e-21	-	-	-	-	-	-	-	-
HDLMBCOA_01588	3.78e-73	-	-	-	-	-	-	-	-
HDLMBCOA_01589	4.58e-103	hsp3	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HDLMBCOA_01590	1.36e-112	-	-	-	-	-	-	-	-
HDLMBCOA_01591	1.22e-81	-	-	-	-	-	-	-	-
HDLMBCOA_01592	4.98e-275	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
HDLMBCOA_01593	1.7e-70	-	-	-	-	-	-	-	-
HDLMBCOA_01594	3.46e-87	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
HDLMBCOA_01595	9.97e-94	spxA	-	-	P	ko:K16509	-	ko00000	ArsC family
HDLMBCOA_01596	2.14e-86	-	-	-	K	ko:K22296	-	ko00000,ko03000	Winged helix DNA-binding domain
HDLMBCOA_01597	6.47e-208	-	-	-	GM	-	-	-	NmrA-like family
HDLMBCOA_01598	4.75e-112	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
HDLMBCOA_01599	4.28e-216	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HDLMBCOA_01600	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HDLMBCOA_01601	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HDLMBCOA_01602	1.19e-34	-	-	-	S	-	-	-	Belongs to the LOG family
HDLMBCOA_01603	7.12e-256	glmS2	-	-	M	-	-	-	SIS domain
HDLMBCOA_01604	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HDLMBCOA_01605	3.05e-281	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
HDLMBCOA_01606	2.32e-160	-	-	-	S	-	-	-	YjbR
HDLMBCOA_01608	0.0	cadA	-	-	P	-	-	-	P-type ATPase
HDLMBCOA_01609	0.0	-	-	-	U	ko:K03451	-	ko00000	Belongs to the BCCT transporter (TC 2.A.15) family
HDLMBCOA_01610	8.79e-156	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HDLMBCOA_01611	4.29e-101	-	-	-	-	-	-	-	-
HDLMBCOA_01612	8.46e-50	-	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
HDLMBCOA_01613	2.42e-127	-	-	-	FG	-	-	-	HIT domain
HDLMBCOA_01614	6.07e-223	ydhF	-	-	S	-	-	-	Aldo keto reductase
HDLMBCOA_01615	8.93e-71	-	-	-	S	-	-	-	Pfam:DUF59
HDLMBCOA_01616	2.64e-205	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HDLMBCOA_01617	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
HDLMBCOA_01618	3.62e-247	-	-	-	V	-	-	-	Beta-lactamase
HDLMBCOA_01619	3.74e-125	-	-	-	V	-	-	-	VanZ like family
HDLMBCOA_01620	6.37e-117	ecsA_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HDLMBCOA_01621	9.06e-112	-	-	-	-	-	-	-	-
HDLMBCOA_01622	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HDLMBCOA_01623	3.2e-70	-	-	-	-	-	-	-	-
HDLMBCOA_01624	3.15e-78	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HDLMBCOA_01625	1.57e-179	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HDLMBCOA_01626	6.42e-123	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HDLMBCOA_01627	9.99e-53	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HDLMBCOA_01628	1.6e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HDLMBCOA_01629	7.69e-300	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HDLMBCOA_01630	1.46e-77	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HDLMBCOA_01631	2.85e-293	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HDLMBCOA_01632	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HDLMBCOA_01633	4.49e-167	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HDLMBCOA_01634	3.33e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HDLMBCOA_01635	2.17e-244	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HDLMBCOA_01636	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HDLMBCOA_01637	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
HDLMBCOA_01638	7.09e-76	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HDLMBCOA_01639	1.61e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HDLMBCOA_01640	1.84e-160	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HDLMBCOA_01641	3.16e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HDLMBCOA_01642	1.21e-209	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HDLMBCOA_01643	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HDLMBCOA_01644	1.62e-173	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HDLMBCOA_01645	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HDLMBCOA_01646	4.09e-222	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HDLMBCOA_01647	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HDLMBCOA_01648	5.04e-278	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HDLMBCOA_01649	3.93e-41	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HDLMBCOA_01650	2.83e-144	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HDLMBCOA_01651	8.28e-73	-	-	-	-	-	-	-	-
HDLMBCOA_01652	1.36e-136	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HDLMBCOA_01653	3.8e-224	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HDLMBCOA_01654	7.11e-135	opuCB	-	-	E	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HDLMBCOA_01655	4.51e-284	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HDLMBCOA_01656	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HDLMBCOA_01657	5.28e-100	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HDLMBCOA_01658	4.49e-192	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HDLMBCOA_01659	1.16e-200	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HDLMBCOA_01660	7.55e-44	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HDLMBCOA_01661	2.81e-313	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HDLMBCOA_01662	4.82e-194	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HDLMBCOA_01663	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HDLMBCOA_01664	1.24e-52	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
HDLMBCOA_01665	5.6e-41	-	-	-	-	-	-	-	-
HDLMBCOA_01666	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HDLMBCOA_01667	5.9e-131	-	-	-	L	-	-	-	Integrase
HDLMBCOA_01668	3.4e-85	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HDLMBCOA_01669	5.67e-231	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HDLMBCOA_01670	2.81e-257	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HDLMBCOA_01671	3.59e-241	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HDLMBCOA_01672	3.44e-210	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HDLMBCOA_01673	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HDLMBCOA_01674	3.85e-76	ywjH	-	-	S	-	-	-	Protein of unknown function (DUF1634)
HDLMBCOA_01675	4.78e-171	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HDLMBCOA_01676	1.36e-208	lysR5	-	-	K	-	-	-	LysR substrate binding domain
HDLMBCOA_01677	2.12e-252	-	-	-	M	-	-	-	MucBP domain
HDLMBCOA_01678	0.0	-	-	-	-	-	-	-	-
HDLMBCOA_01679	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HDLMBCOA_01680	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HDLMBCOA_01681	4.77e-216	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
HDLMBCOA_01682	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HDLMBCOA_01683	7.89e-290	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
HDLMBCOA_01684	3.5e-93	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
HDLMBCOA_01685	1.13e-257	yueF	-	-	S	-	-	-	AI-2E family transporter
HDLMBCOA_01686	4.22e-215	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HDLMBCOA_01687	7.17e-39	-	-	-	S	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
HDLMBCOA_01688	8.01e-64	-	-	-	K	-	-	-	sequence-specific DNA binding
HDLMBCOA_01689	5.34e-168	lytE	-	-	M	-	-	-	NlpC/P60 family
HDLMBCOA_01690	6.62e-138	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
HDLMBCOA_01691	3.93e-180	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
HDLMBCOA_01692	1.39e-169	-	-	-	-	-	-	-	-
HDLMBCOA_01693	3.82e-128	-	-	-	K	-	-	-	DNA-templated transcription, initiation
HDLMBCOA_01694	5.7e-36	-	-	-	-	-	-	-	-
HDLMBCOA_01695	1.17e-42	-	-	-	-	-	-	-	-
HDLMBCOA_01696	2.54e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
HDLMBCOA_01697	2.59e-69	-	-	-	-	-	-	-	-
HDLMBCOA_01698	1.38e-155	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
HDLMBCOA_01699	1.71e-304	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HDLMBCOA_01700	2.94e-190	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HDLMBCOA_01701	2.31e-256	cps3I	-	-	G	-	-	-	Acyltransferase family
HDLMBCOA_01702	7.33e-142	cps3H	-	-	-	-	-	-	-
HDLMBCOA_01703	1.18e-98	cps3H	-	-	-	-	-	-	-
HDLMBCOA_01704	4.09e-208	cps3F	-	-	-	-	-	-	-
HDLMBCOA_01705	3.98e-143	cps3E	-	-	-	-	-	-	-
HDLMBCOA_01706	5.58e-260	cps3D	-	-	-	-	-	-	-
HDLMBCOA_01707	6.91e-283	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HDLMBCOA_01708	5.23e-74	cps3B	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
HDLMBCOA_01709	7.78e-140	cps3B	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
HDLMBCOA_01710	7.37e-83	pts26BCA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HDLMBCOA_01711	1.13e-200	-	-	-	S	-	-	-	Putative adhesin
HDLMBCOA_01712	1.73e-132	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
HDLMBCOA_01713	2.86e-68	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator
HDLMBCOA_01714	1.07e-127	-	-	-	KT	-	-	-	response to antibiotic
HDLMBCOA_01715	1.26e-161	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HDLMBCOA_01716	3.02e-176	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HDLMBCOA_01717	2.11e-158	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HDLMBCOA_01718	2.13e-167	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HDLMBCOA_01719	2.07e-302	-	-	-	EK	-	-	-	Aminotransferase, class I
HDLMBCOA_01720	3.36e-216	-	-	-	K	-	-	-	LysR substrate binding domain
HDLMBCOA_01721	1.49e-188	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HDLMBCOA_01722	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HDLMBCOA_01723	1.66e-288	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Nucleoside
HDLMBCOA_01724	1.81e-168	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HDLMBCOA_01725	8.63e-191	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HDLMBCOA_01726	1.01e-175	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
HDLMBCOA_01727	7.16e-201	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HDLMBCOA_01728	1.4e-40	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
HDLMBCOA_01729	6.6e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HDLMBCOA_01730	3.49e-160	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
HDLMBCOA_01731	3.49e-270	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HDLMBCOA_01732	3.3e-208	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HDLMBCOA_01733	1.62e-159	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
HDLMBCOA_01734	1.14e-159	vanR	-	-	K	-	-	-	response regulator
HDLMBCOA_01735	5.61e-273	hpk31	-	-	T	-	-	-	Histidine kinase
HDLMBCOA_01736	3.61e-303	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HDLMBCOA_01737	6.77e-116	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HDLMBCOA_01738	4.83e-166	-	-	-	E	-	-	-	branched-chain amino acid
HDLMBCOA_01739	5.93e-73	-	-	-	S	-	-	-	branched-chain amino acid
HDLMBCOA_01740	3.37e-141	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HDLMBCOA_01741	6.09e-72	-	-	-	-	-	-	-	-
HDLMBCOA_01742	5.61e-98	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HDLMBCOA_01743	2.47e-125	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
HDLMBCOA_01744	9.58e-35	-	-	-	S	-	-	-	Protein of unknown function (DUF4064)
HDLMBCOA_01745	1.86e-256	pkn2	-	-	KLT	-	-	-	Protein tyrosine kinase
HDLMBCOA_01746	3.32e-210	-	-	-	-	-	-	-	-
HDLMBCOA_01747	1.49e-294	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HDLMBCOA_01748	2.42e-143	-	-	-	-	-	-	-	-
HDLMBCOA_01749	9.28e-271	xylR	-	-	GK	-	-	-	ROK family
HDLMBCOA_01750	3.09e-231	ydbI	-	-	K	-	-	-	AI-2E family transporter
HDLMBCOA_01751	5.06e-168	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HDLMBCOA_01752	6.79e-53	-	-	-	-	-	-	-	-
HDLMBCOA_01753	7.85e-114	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDLMBCOA_01754	2.5e-66	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HDLMBCOA_01755	1.74e-67	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HDLMBCOA_01756	0.0	oatA	-	-	I	-	-	-	Acyltransferase
HDLMBCOA_01757	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HDLMBCOA_01758	1.94e-42	-	-	-	O	-	-	-	OsmC-like protein
HDLMBCOA_01759	2.23e-32	-	-	-	O	-	-	-	OsmC-like protein
HDLMBCOA_01760	3.8e-61	-	-	-	-	-	-	-	-
HDLMBCOA_01761	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
HDLMBCOA_01762	6.12e-115	-	-	-	-	-	-	-	-
HDLMBCOA_01763	1.23e-189	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
HDLMBCOA_01764	7.48e-96	-	-	-	F	-	-	-	Nudix hydrolase
HDLMBCOA_01765	1.48e-27	-	-	-	-	-	-	-	-
HDLMBCOA_01766	2.45e-134	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
HDLMBCOA_01767	2.02e-106	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HDLMBCOA_01768	8.84e-18	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
HDLMBCOA_01769	1.01e-188	-	-	-	-	-	-	-	-
HDLMBCOA_01770	6.94e-146	gph1	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD hydrolase, family IA, variant
HDLMBCOA_01771	3.21e-268	aspC	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HDLMBCOA_01772	4.18e-217	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HDLMBCOA_01773	1.28e-54	-	-	-	-	-	-	-	-
HDLMBCOA_01775	2.3e-172	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HDLMBCOA_01776	3.39e-190	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HDLMBCOA_01777	3.14e-140	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HDLMBCOA_01778	1.27e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HDLMBCOA_01779	7.04e-108	-	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HDLMBCOA_01780	7.77e-197	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HDLMBCOA_01781	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HDLMBCOA_01782	4.87e-180	-	3.5.1.105	-	G	ko:K03478	-	ko00000,ko01000	YdjC-like protein
HDLMBCOA_01783	0.0	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HDLMBCOA_01784	6.26e-96	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HDLMBCOA_01785	8.87e-191	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
HDLMBCOA_01786	2.53e-92	-	-	-	K	-	-	-	MarR family
HDLMBCOA_01787	5.34e-268	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HDLMBCOA_01788	2.93e-109	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HDLMBCOA_01789	1.81e-128	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDLMBCOA_01790	5.95e-300	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HDLMBCOA_01791	3.79e-101	rppH3	-	-	F	-	-	-	NUDIX domain
HDLMBCOA_01792	2.27e-53	sugE	-	-	U	ko:K11741	-	ko00000,ko02000	Multidrug resistance protein
HDLMBCOA_01793	1.88e-35	-	-	-	-	-	-	-	-
HDLMBCOA_01794	1.35e-165	pgm3	-	-	G	-	-	-	Phosphoglycerate mutase family
HDLMBCOA_01795	2.07e-161	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
HDLMBCOA_01796	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
HDLMBCOA_01797	4.16e-227	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
HDLMBCOA_01798	1.11e-143	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
HDLMBCOA_01799	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HDLMBCOA_01800	1.46e-211	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
HDLMBCOA_01801	1.22e-227	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HDLMBCOA_01802	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HDLMBCOA_01804	3.72e-200	bglG4	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HDLMBCOA_01805	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HDLMBCOA_01806	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HDLMBCOA_01807	2.26e-269	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HDLMBCOA_01808	2.4e-202	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
HDLMBCOA_01809	5.07e-211	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HDLMBCOA_01810	1.87e-316	pts29C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDLMBCOA_01811	5.44e-174	-	-	-	K	-	-	-	UTRA domain
HDLMBCOA_01812	2.63e-200	estA	-	-	S	-	-	-	Putative esterase
HDLMBCOA_01813	4.93e-82	-	-	-	-	-	-	-	-
HDLMBCOA_01814	1.12e-262	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HDLMBCOA_01815	1.73e-215	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
HDLMBCOA_01816	5.56e-212	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
HDLMBCOA_01817	1.64e-202	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HDLMBCOA_01818	8.13e-206	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HDLMBCOA_01819	1.71e-207	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HDLMBCOA_01820	3.3e-281	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HDLMBCOA_01821	4.62e-224	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
HDLMBCOA_01822	1.12e-212	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HDLMBCOA_01823	1.49e-171	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HDLMBCOA_01824	1.23e-228	apbE3	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HDLMBCOA_01825	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HDLMBCOA_01826	2.02e-85	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
HDLMBCOA_01827	8.93e-249	tas3	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
HDLMBCOA_01828	3.69e-232	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HDLMBCOA_01829	4.27e-253	galM3	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HDLMBCOA_01830	0.0	lacP	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HDLMBCOA_01831	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HDLMBCOA_01832	1.64e-238	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
HDLMBCOA_01833	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HDLMBCOA_01834	1.65e-286	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HDLMBCOA_01835	1.26e-245	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HDLMBCOA_01836	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HDLMBCOA_01837	1.19e-234	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HDLMBCOA_01838	3.4e-100	-	-	-	K	ko:K07726	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
HDLMBCOA_01839	6.22e-140	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
HDLMBCOA_01840	5.27e-235	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HDLMBCOA_01841	6.77e-50	-	-	-	P	ko:K06610	-	ko00000,ko02000	Major Facilitator Superfamily
HDLMBCOA_01842	5.24e-48	ecsA_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HDLMBCOA_01843	1.64e-284	XK27_00765	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HDLMBCOA_01844	9.37e-165	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Anthranilate synthase component I, N terminal region
HDLMBCOA_01845	8.08e-135	trpG	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Peptidase C26
HDLMBCOA_01846	6.03e-226	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HDLMBCOA_01847	1.2e-165	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
HDLMBCOA_01848	1.57e-142	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
HDLMBCOA_01849	3.1e-288	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HDLMBCOA_01850	3.96e-182	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HDLMBCOA_01851	5.89e-126	entB	-	-	Q	-	-	-	Isochorismatase family
HDLMBCOA_01852	2.04e-226	-	1.6.5.5	-	C	ko:K00344	-	ko00000,ko01000	Zinc-binding dehydrogenase
HDLMBCOA_01853	1.95e-88	ybbJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HDLMBCOA_01854	4.84e-278	-	-	-	E	-	-	-	glutamate:sodium symporter activity
HDLMBCOA_01855	5.37e-271	hipO1	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	Peptidase family M20/M25/M40
HDLMBCOA_01856	2.69e-252	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HDLMBCOA_01857	1.49e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
HDLMBCOA_01859	6.84e-186	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HDLMBCOA_01860	1.62e-229	yneE	-	-	K	-	-	-	Transcriptional regulator
HDLMBCOA_01861	8.55e-99	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HDLMBCOA_01862	1.62e-229	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HDLMBCOA_01863	6.16e-48	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HDLMBCOA_01864	3.47e-215	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
HDLMBCOA_01865	1.26e-162	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HDLMBCOA_01866	3.11e-289	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HDLMBCOA_01867	2.14e-95	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HDLMBCOA_01868	1.71e-91	fabZ2	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
HDLMBCOA_01869	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
HDLMBCOA_01870	6.43e-203	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HDLMBCOA_01871	4.82e-179	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
HDLMBCOA_01872	2.29e-175	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
HDLMBCOA_01873	5.01e-129	-	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
HDLMBCOA_01874	1.48e-161	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HDLMBCOA_01875	7.52e-207	-	-	-	K	-	-	-	LysR substrate binding domain
HDLMBCOA_01876	2.01e-113	ykhA	-	-	I	-	-	-	Thioesterase superfamily
HDLMBCOA_01877	5.13e-245	rsgA_2	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HDLMBCOA_01878	6.05e-121	-	-	-	K	-	-	-	transcriptional regulator
HDLMBCOA_01879	0.0	-	-	-	EGP	-	-	-	Major Facilitator
HDLMBCOA_01880	1.14e-193	-	-	-	O	-	-	-	Band 7 protein
HDLMBCOA_01881	1.48e-71	-	-	-	-	-	-	-	-
HDLMBCOA_01882	2.02e-39	-	-	-	-	-	-	-	-
HDLMBCOA_01883	6.57e-274	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HDLMBCOA_01884	1.05e-41	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HDLMBCOA_01885	9.96e-147	-	1.14.99.53	AA10	S	ko:K21713	-	ko00000,ko01000	Lytic polysaccharide mono-oxygenase, cellulose-degrading
HDLMBCOA_01886	5.93e-60	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HDLMBCOA_01887	2.05e-55	-	-	-	-	-	-	-	-
HDLMBCOA_01888	6.05e-108	tspO	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	TspO/MBR family
HDLMBCOA_01889	1.07e-99	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HDLMBCOA_01890	5.58e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
HDLMBCOA_01891	3.6e-211	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HDLMBCOA_01892	2.82e-91	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HDLMBCOA_01893	1.7e-96	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
HDLMBCOA_01894	1.43e-129	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HDLMBCOA_01895	3.49e-248	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HDLMBCOA_01896	2.33e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HDLMBCOA_01897	7.97e-71	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
HDLMBCOA_01898	1.55e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HDLMBCOA_01899	8.15e-125	-	-	-	K	-	-	-	Transcriptional regulator
HDLMBCOA_01900	9.81e-27	-	-	-	-	-	-	-	-
HDLMBCOA_01903	2.97e-41	-	-	-	-	-	-	-	-
HDLMBCOA_01904	3.11e-73	-	-	-	-	-	-	-	-
HDLMBCOA_01905	2.92e-126	-	-	-	S	-	-	-	Protein conserved in bacteria
HDLMBCOA_01906	1.34e-232	-	-	-	-	-	-	-	-
HDLMBCOA_01907	1.77e-205	-	-	-	-	-	-	-	-
HDLMBCOA_01908	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HDLMBCOA_01909	7.79e-85	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
HDLMBCOA_01910	3.8e-224	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HDLMBCOA_01911	7.77e-179	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
HDLMBCOA_01912	1.44e-31	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
HDLMBCOA_01913	1.15e-89	yqhL	-	-	P	-	-	-	Rhodanese-like protein
HDLMBCOA_01914	1.62e-141	pepE	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
HDLMBCOA_01915	4.31e-230	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
HDLMBCOA_01916	6.33e-46	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
HDLMBCOA_01917	7.09e-153	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
HDLMBCOA_01918	9.29e-132	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HDLMBCOA_01919	5.33e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HDLMBCOA_01920	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HDLMBCOA_01921	0.0	-	-	-	S	-	-	-	membrane
HDLMBCOA_01922	2.5e-71	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
HDLMBCOA_01923	2.33e-98	-	-	-	K	-	-	-	LytTr DNA-binding domain
HDLMBCOA_01924	3.78e-143	-	-	-	S	-	-	-	membrane
HDLMBCOA_01925	1.09e-105	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HDLMBCOA_01926	7.5e-146	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HDLMBCOA_01927	6.11e-249	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HDLMBCOA_01928	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HDLMBCOA_01929	6.88e-257	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HDLMBCOA_01930	1.09e-83	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HDLMBCOA_01931	1.72e-120	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HDLMBCOA_01932	4.46e-179	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HDLMBCOA_01933	1.37e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HDLMBCOA_01934	1.4e-208	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HDLMBCOA_01935	1.77e-122	-	-	-	S	-	-	-	SdpI/YhfL protein family
HDLMBCOA_01936	9.59e-289	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HDLMBCOA_01937	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
HDLMBCOA_01938	1.34e-191	ubiA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HDLMBCOA_01941	1.01e-158	int7	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HDLMBCOA_01942	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HDLMBCOA_01943	1.68e-312	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HDLMBCOA_01944	5.75e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDLMBCOA_01945	1.14e-297	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
HDLMBCOA_01946	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDLMBCOA_01947	8.59e-27	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
HDLMBCOA_01948	8.49e-266	pbpX2	-	-	V	-	-	-	Beta-lactamase
HDLMBCOA_01949	2.54e-266	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HDLMBCOA_01950	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HDLMBCOA_01951	4.52e-111	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HDLMBCOA_01952	4.42e-248	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HDLMBCOA_01953	1.19e-169	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
HDLMBCOA_01954	1.53e-241	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HDLMBCOA_01955	8.94e-221	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HDLMBCOA_01956	2.41e-113	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HDLMBCOA_01957	2.02e-190	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
HDLMBCOA_01958	1.9e-41	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
HDLMBCOA_01959	1.24e-297	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HDLMBCOA_01960	1.63e-121	-	-	-	-	-	-	-	-
HDLMBCOA_01961	3.67e-275	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HDLMBCOA_01962	0.0	-	-	-	G	-	-	-	Major Facilitator
HDLMBCOA_01963	3.04e-71	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HDLMBCOA_01964	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HDLMBCOA_01965	3.28e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
HDLMBCOA_01966	2.95e-65	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
HDLMBCOA_01967	4.46e-275	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HDLMBCOA_01968	9.74e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HDLMBCOA_01969	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HDLMBCOA_01970	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HDLMBCOA_01971	4.64e-294	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HDLMBCOA_01972	1.13e-175	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HDLMBCOA_01973	3.17e-190	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HDLMBCOA_01974	0.0	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Bacterial SH3 domain
HDLMBCOA_01975	4.26e-250	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HDLMBCOA_01976	4.84e-77	-	-	-	-	-	-	-	-
HDLMBCOA_01977	4.05e-98	-	-	-	-	-	-	-	-
HDLMBCOA_01978	6.94e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF2798)
HDLMBCOA_01979	1.57e-71	-	-	-	-	-	-	-	-
HDLMBCOA_01980	1.11e-61	-	-	-	-	-	-	-	-
HDLMBCOA_01981	6.69e-263	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
HDLMBCOA_01982	9.89e-74	ytpP	-	-	CO	-	-	-	Thioredoxin
HDLMBCOA_01983	2.4e-186	-	-	-	S	ko:K06889	-	ko00000	Dienelactone hydrolase family
HDLMBCOA_01984	5.82e-89	-	-	-	-	-	-	-	-
HDLMBCOA_01985	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HDLMBCOA_01986	4.83e-64	-	-	-	-	-	-	-	-
HDLMBCOA_01987	3.68e-77	-	-	-	-	-	-	-	-
HDLMBCOA_01989	1.08e-209	-	-	-	-	-	-	-	-
HDLMBCOA_01990	1.4e-95	-	-	-	K	-	-	-	Transcriptional regulator
HDLMBCOA_01991	0.0	pepF2	-	-	E	-	-	-	Oligopeptidase F
HDLMBCOA_01992	4.62e-223	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HDLMBCOA_01993	7.2e-61	-	-	-	S	-	-	-	Enterocin A Immunity
HDLMBCOA_01994	8.34e-86	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
HDLMBCOA_01995	5e-162	skfE	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HDLMBCOA_01996	2.66e-172	-	-	-	-	-	-	-	-
HDLMBCOA_01997	9.38e-139	pncA	-	-	Q	-	-	-	Isochorismatase family
HDLMBCOA_01998	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HDLMBCOA_01999	0.0	nhaP2	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HDLMBCOA_02000	8.97e-253	yhhX	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
HDLMBCOA_02001	9.51e-49	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HDLMBCOA_02002	2.39e-153	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HDLMBCOA_02003	4.16e-150	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HDLMBCOA_02004	1.48e-201	ccpB	-	-	K	-	-	-	lacI family
HDLMBCOA_02005	2.2e-157	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HDLMBCOA_02006	3.45e-209	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HDLMBCOA_02007	1.23e-228	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
HDLMBCOA_02008	2.57e-128	-	-	-	C	-	-	-	Nitroreductase family
HDLMBCOA_02009	6.04e-217	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
HDLMBCOA_02010	2.89e-248	-	-	-	S	-	-	-	domain, Protein
HDLMBCOA_02011	2.14e-183	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HDLMBCOA_02012	4.68e-235	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HDLMBCOA_02013	0.0	traA	-	-	L	-	-	-	MobA MobL family protein
HDLMBCOA_02014	0.0	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HDLMBCOA_02015	3.6e-42	-	-	-	-	-	-	-	-
HDLMBCOA_02016	1.4e-238	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HDLMBCOA_02017	8.77e-82	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain
HDLMBCOA_02018	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HDLMBCOA_02019	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HDLMBCOA_02020	4.05e-148	prrC	-	-	-	-	-	-	-
HDLMBCOA_02021	2.23e-124	tnpR	-	-	L	-	-	-	Resolvase, N terminal domain
HDLMBCOA_02022	4.22e-77	-	-	-	J	-	-	-	tRNA cytidylyltransferase activity
HDLMBCOA_02024	2.53e-167	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
HDLMBCOA_02025	1.13e-118	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HDLMBCOA_02026	1.08e-235	-	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HDLMBCOA_02027	0.0	-	-	-	C	-	-	-	FAD binding domain
HDLMBCOA_02029	0.0	pbg9	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HDLMBCOA_02030	2.7e-186	glpK3	2.7.1.30	-	G	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	FGGY family of carbohydrate kinases, C-terminal domain
HDLMBCOA_02031	6.32e-134	-	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transketolase, pyrimidine binding domain
HDLMBCOA_02032	2.66e-147	-	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transketolase, thiamine diphosphate binding domain
HDLMBCOA_02033	2.58e-310	-	-	-	G	-	-	-	isomerase
HDLMBCOA_02034	5.31e-121	purR13	-	-	K	ko:K02529	-	ko00000,ko03000	Bacterial regulatory proteins, lacI family
HDLMBCOA_02035	3.6e-185	-	-	-	G	-	-	-	Protein of unknown function (DUF4038)
HDLMBCOA_02036	5.27e-242	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HDLMBCOA_02037	1.8e-271	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
HDLMBCOA_02038	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HDLMBCOA_02039	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HDLMBCOA_02040	1.14e-215	-	-	-	EGP	-	-	-	Major Facilitator
HDLMBCOA_02042	7.81e-148	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HDLMBCOA_02043	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HDLMBCOA_02044	3.81e-172	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HDLMBCOA_02045	1.77e-282	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HDLMBCOA_02046	1.46e-126	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDLMBCOA_02047	6.24e-215	-	-	-	GM	-	-	-	NmrA-like family
HDLMBCOA_02048	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HDLMBCOA_02049	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HDLMBCOA_02050	6.12e-29	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HDLMBCOA_02051	1.62e-62	-	-	-	S	-	-	-	Domain of unknown function (DUF1905)
HDLMBCOA_02052	1.27e-83	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HDLMBCOA_02053	3.27e-170	-	-	-	S	-	-	-	KR domain
HDLMBCOA_02054	1.66e-125	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDLMBCOA_02055	3.47e-244	-	1.1.1.219	-	GM	ko:K00091	-	ko00000,ko01000	Male sterility protein
HDLMBCOA_02056	1.09e-130	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HDLMBCOA_02057	1.33e-227	ydhF	-	-	S	-	-	-	Aldo keto reductase
HDLMBCOA_02058	0.0	yfjF	-	-	U	-	-	-	Sugar (and other) transporter
HDLMBCOA_02059	7.57e-141	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDLMBCOA_02060	3.35e-217	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HDLMBCOA_02061	6.37e-188	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HDLMBCOA_02062	1.81e-228	fhuB	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HDLMBCOA_02063	1.92e-218	fhuG	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HDLMBCOA_02064	3.74e-120	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDLMBCOA_02065	9.16e-209	-	-	-	GM	-	-	-	NmrA-like family
HDLMBCOA_02066	2.47e-168	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HDLMBCOA_02067	4.01e-96	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
HDLMBCOA_02068	1.5e-193	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HDLMBCOA_02069	3.71e-83	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HDLMBCOA_02070	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HDLMBCOA_02071	3.45e-231	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HDLMBCOA_02072	0.0	pox2	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HDLMBCOA_02073	5.47e-198	ribC1	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HDLMBCOA_02074	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HDLMBCOA_02075	1.79e-287	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HDLMBCOA_02076	5.55e-27	-	-	-	-	-	-	-	-
HDLMBCOA_02077	6.16e-107	-	-	-	K	-	-	-	Transcriptional regulator
HDLMBCOA_02078	9.11e-195	licD	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
HDLMBCOA_02079	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HDLMBCOA_02080	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HDLMBCOA_02081	4.45e-226	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HDLMBCOA_02082	1.31e-315	-	-	-	EGP	-	-	-	Major Facilitator
HDLMBCOA_02083	1.71e-116	-	-	-	V	-	-	-	VanZ like family
HDLMBCOA_02084	3.88e-46	-	-	-	-	-	-	-	-
HDLMBCOA_02085	5.45e-94	spx1	-	-	P	ko:K16509	-	ko00000	ArsC family
HDLMBCOA_02087	6.37e-186	-	-	-	-	-	-	-	-
HDLMBCOA_02088	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HDLMBCOA_02089	3.51e-197	-	-	-	G	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
HDLMBCOA_02090	2.87e-168	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
HDLMBCOA_02091	2.49e-95	-	-	-	-	-	-	-	-
HDLMBCOA_02092	2.79e-69	-	-	-	-	-	-	-	-
HDLMBCOA_02093	4.44e-232	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HDLMBCOA_02094	1.21e-135	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDLMBCOA_02095	8.04e-190	-	3.1.3.23	-	S	ko:K07757	-	ko00000,ko01000	Sucrose-6F-phosphate phosphohydrolase
HDLMBCOA_02096	5.44e-159	-	-	-	T	-	-	-	EAL domain
HDLMBCOA_02097	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HDLMBCOA_02098	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HDLMBCOA_02099	2.18e-182	ybbR	-	-	S	-	-	-	YbbR-like protein
HDLMBCOA_02100	2.39e-191	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HDLMBCOA_02101	1.52e-13	-	-	-	S	-	-	-	Protein of unknown function (DUF1361)
HDLMBCOA_02102	2.89e-58	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
HDLMBCOA_02103	4.66e-213	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
HDLMBCOA_02104	2.96e-209	yhxD	-	-	IQ	-	-	-	KR domain
HDLMBCOA_02106	1.97e-92	-	-	-	-	-	-	-	-
HDLMBCOA_02107	2.47e-185	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HDLMBCOA_02108	0.0	-	-	-	E	-	-	-	Amino Acid
HDLMBCOA_02109	1.67e-86	lysM	-	-	M	-	-	-	LysM domain
HDLMBCOA_02110	4.2e-286	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
HDLMBCOA_02111	6.8e-272	adhC	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
HDLMBCOA_02112	0.0	copA	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HDLMBCOA_02113	1.49e-58	-	-	-	S	-	-	-	Cupredoxin-like domain
HDLMBCOA_02114	1.36e-84	-	-	-	S	-	-	-	Cupredoxin-like domain
HDLMBCOA_02115	0.0	aapA	-	-	M	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HDLMBCOA_02116	2.81e-181	-	-	-	K	-	-	-	Helix-turn-helix domain
HDLMBCOA_02117	1.47e-51	-	-	-	S	ko:K07343	-	ko00000	TfoX C-terminal domain
HDLMBCOA_02118	1.65e-221	hpk9	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HDLMBCOA_02119	4.25e-46	hpk9	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HDLMBCOA_02120	0.0	-	-	-	-	-	-	-	-
HDLMBCOA_02121	2.69e-99	-	-	-	-	-	-	-	-
HDLMBCOA_02122	4.22e-245	-	-	-	S	-	-	-	Cell surface protein
HDLMBCOA_02123	6.02e-137	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HDLMBCOA_02124	2.67e-225	-	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
HDLMBCOA_02125	1.27e-90	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HDLMBCOA_02126	1.01e-64	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
HDLMBCOA_02127	7.3e-62	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
HDLMBCOA_02128	7.66e-237	ynjC	-	-	S	-	-	-	Cell surface protein
HDLMBCOA_02129	2.7e-131	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HDLMBCOA_02130	2.01e-81	-	-	-	-	-	-	-	-
HDLMBCOA_02131	5.7e-302	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
HDLMBCOA_02132	4.13e-157	-	-	-	-	-	-	-	-
HDLMBCOA_02133	4.31e-149	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HDLMBCOA_02134	3.25e-81	ytcD	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HDLMBCOA_02135	8.35e-43	-	-	-	EGP	-	-	-	Major Facilitator
HDLMBCOA_02136	1.52e-135	-	-	-	GM	-	-	-	NAD(P)H-binding
HDLMBCOA_02137	1.66e-247	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HDLMBCOA_02138	6.82e-193	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HDLMBCOA_02139	1.28e-45	-	-	-	-	-	-	-	-
HDLMBCOA_02140	2.1e-99	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HDLMBCOA_02141	2.09e-124	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
HDLMBCOA_02142	1.02e-161	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HDLMBCOA_02143	2.31e-79	-	-	-	-	-	-	-	-
HDLMBCOA_02144	5.29e-131	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HDLMBCOA_02145	2.33e-283	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HDLMBCOA_02146	1.07e-131	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
HDLMBCOA_02147	1.8e-249	-	-	-	C	-	-	-	Aldo/keto reductase family
HDLMBCOA_02149	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HDLMBCOA_02150	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HDLMBCOA_02151	6.27e-316	-	-	-	EGP	-	-	-	Major Facilitator
HDLMBCOA_02155	2.06e-314	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
HDLMBCOA_02156	3.01e-124	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
HDLMBCOA_02157	6.88e-71	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HDLMBCOA_02158	4.19e-197	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
HDLMBCOA_02159	1.34e-132	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HDLMBCOA_02160	1.24e-125	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HDLMBCOA_02161	3.27e-171	-	-	-	M	-	-	-	Phosphotransferase enzyme family
HDLMBCOA_02162	3.18e-282	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HDLMBCOA_02163	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HDLMBCOA_02164	1.9e-189	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HDLMBCOA_02165	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
HDLMBCOA_02166	1.11e-45	-	-	-	-	-	-	-	-
HDLMBCOA_02167	2.29e-48	-	-	-	-	-	-	-	-
HDLMBCOA_02168	5.92e-107	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
HDLMBCOA_02169	1.01e-221	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	NlpC/P60 family
HDLMBCOA_02170	2e-207	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HDLMBCOA_02172	2.68e-32	-	-	-	-	-	-	-	-
HDLMBCOA_02173	8.05e-178	-	-	-	F	-	-	-	NUDIX domain
HDLMBCOA_02174	5.46e-28	yceI	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major Facilitator
HDLMBCOA_02175	1.3e-231	yceI	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major Facilitator
HDLMBCOA_02176	1.31e-64	-	-	-	-	-	-	-	-
HDLMBCOA_02177	6.24e-120	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
HDLMBCOA_02179	2.98e-217	-	-	-	EG	-	-	-	EamA-like transporter family
HDLMBCOA_02180	2.49e-50	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
HDLMBCOA_02181	2.12e-308	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HDLMBCOA_02182	5.89e-173	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
HDLMBCOA_02183	0.0	yclK	-	-	T	-	-	-	Histidine kinase
HDLMBCOA_02184	1.83e-277	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
HDLMBCOA_02185	2.51e-200	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HDLMBCOA_02186	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HDLMBCOA_02187	2.1e-33	-	-	-	-	-	-	-	-
HDLMBCOA_02188	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDLMBCOA_02189	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HDLMBCOA_02190	0.0	-	3.6.3.44	-	P	ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter transmembrane region
HDLMBCOA_02191	4.63e-24	-	-	-	-	-	-	-	-
HDLMBCOA_02192	2.16e-26	-	-	-	-	-	-	-	-
HDLMBCOA_02193	9.35e-24	-	-	-	-	-	-	-	-
HDLMBCOA_02194	9.35e-24	-	-	-	-	-	-	-	-
HDLMBCOA_02195	9.35e-24	-	-	-	-	-	-	-	-
HDLMBCOA_02196	1.07e-26	-	-	-	-	-	-	-	-
HDLMBCOA_02197	1.56e-22	-	-	-	-	-	-	-	-
HDLMBCOA_02198	3.26e-24	-	-	-	-	-	-	-	-
HDLMBCOA_02199	6.58e-24	-	-	-	-	-	-	-	-
HDLMBCOA_02200	0.0	inlJ	-	-	M	-	-	-	MucBP domain
HDLMBCOA_02201	7.59e-179	-	-	-	D	-	-	-	nuclear chromosome segregation
HDLMBCOA_02202	2.1e-254	-	-	-	D	-	-	-	nuclear chromosome segregation
HDLMBCOA_02203	1.27e-109	-	-	-	K	-	-	-	MarR family
HDLMBCOA_02204	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
HDLMBCOA_02205	1.49e-155	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HDLMBCOA_02206	2.34e-72	trxA3	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin-like domain
HDLMBCOA_02207	4.82e-55	yrkD	-	-	S	-	-	-	Metal-sensitive transcriptional repressor
HDLMBCOA_02208	1.01e-26	-	-	-	-	-	-	-	-
HDLMBCOA_02209	4.27e-126	dpsB	-	-	P	-	-	-	Belongs to the Dps family
HDLMBCOA_02210	2.98e-44	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
HDLMBCOA_02211	1.82e-152	rcfA	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
HDLMBCOA_02212	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HDLMBCOA_02213	5.23e-107	yoaA	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HDLMBCOA_02214	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
HDLMBCOA_02215	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
HDLMBCOA_02216	1.83e-235	-	-	-	S	-	-	-	Cell surface protein
HDLMBCOA_02217	8.67e-160	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HDLMBCOA_02218	4.23e-129	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HDLMBCOA_02219	7.83e-60	-	-	-	-	-	-	-	-
HDLMBCOA_02220	8.19e-134	yezE	-	-	K	ko:K16137	-	ko00000,ko03000	Bacterial regulatory proteins, tetR family
HDLMBCOA_02221	1.03e-65	-	-	-	-	-	-	-	-
HDLMBCOA_02222	9.34e-317	-	-	-	S	-	-	-	Putative metallopeptidase domain
HDLMBCOA_02223	3.31e-282	-	-	-	S	-	-	-	associated with various cellular activities
HDLMBCOA_02224	1.95e-140	aqpZ	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HDLMBCOA_02225	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
HDLMBCOA_02226	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HDLMBCOA_02227	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
HDLMBCOA_02228	0.0	rafA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HDLMBCOA_02229	2.81e-90	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HDLMBCOA_02230	2.89e-115	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDLMBCOA_02231	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HDLMBCOA_02232	1.23e-199	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HDLMBCOA_02233	2.81e-64	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HDLMBCOA_02234	9.93e-127	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
HDLMBCOA_02235	0.0	pacL1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HDLMBCOA_02236	4.49e-182	-	-	-	F	-	-	-	Phosphorylase superfamily
HDLMBCOA_02237	2.92e-38	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
HDLMBCOA_02238	1.72e-142	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
HDLMBCOA_02239	1.27e-98	-	-	-	K	-	-	-	Transcriptional regulator
HDLMBCOA_02240	3.99e-96	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HDLMBCOA_02241	5.51e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HDLMBCOA_02242	5.38e-290	-	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HDLMBCOA_02243	3.98e-68	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HDLMBCOA_02244	1.74e-114	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
HDLMBCOA_02245	9.05e-136	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
HDLMBCOA_02247	5.09e-203	morA	-	-	S	-	-	-	reductase
HDLMBCOA_02248	8.21e-213	-	1.1.1.65	-	C	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	ko00000,ko00001,ko01000	Aldo keto reductase
HDLMBCOA_02249	1.92e-106	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase like
HDLMBCOA_02250	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
HDLMBCOA_02251	4.29e-102	-	-	-	-	-	-	-	-
HDLMBCOA_02252	0.0	-	-	-	-	-	-	-	-
HDLMBCOA_02253	6.49e-268	-	-	-	C	-	-	-	Oxidoreductase
HDLMBCOA_02254	5.49e-56	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
HDLMBCOA_02255	1.36e-115	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
HDLMBCOA_02256	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HDLMBCOA_02257	2.57e-128	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
HDLMBCOA_02259	4.37e-167	-	-	-	K	ko:K03492	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HDLMBCOA_02260	4.14e-72	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HDLMBCOA_02261	2.47e-179	-	-	-	-	-	-	-	-
HDLMBCOA_02262	1.57e-191	-	-	-	-	-	-	-	-
HDLMBCOA_02263	3.37e-115	-	-	-	-	-	-	-	-
HDLMBCOA_02264	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC
HDLMBCOA_02265	9.48e-265	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HDLMBCOA_02266	7.97e-222	ropB	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HDLMBCOA_02267	2.83e-297	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
HDLMBCOA_02268	4.81e-292	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
HDLMBCOA_02269	1.56e-16	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
HDLMBCOA_02270	2.85e-206	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HDLMBCOA_02271	6.11e-169	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
HDLMBCOA_02272	9.97e-18	-	-	-	-	-	-	-	-
HDLMBCOA_02273	0.0	-	-	-	-	-	-	-	-
HDLMBCOA_02274	2e-52	-	-	-	S	-	-	-	Cytochrome B5
HDLMBCOA_02275	8.68e-118	pts21A	-	-	G	ko:K02755	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HDLMBCOA_02276	4.14e-279	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
HDLMBCOA_02277	1.63e-162	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HDLMBCOA_02278	3.83e-135	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HDLMBCOA_02279	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
HDLMBCOA_02280	1.56e-108	-	-	-	-	-	-	-	-
HDLMBCOA_02281	6.98e-95	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HDLMBCOA_02282	3.08e-241	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HDLMBCOA_02283	1.26e-245	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HDLMBCOA_02284	7.16e-30	-	-	-	-	-	-	-	-
HDLMBCOA_02285	1.84e-134	-	-	-	-	-	-	-	-
HDLMBCOA_02286	3.46e-210	-	-	-	K	-	-	-	LysR substrate binding domain
HDLMBCOA_02287	4.34e-314	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
HDLMBCOA_02288	0.0	-	4.1.1.98	-	H	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HDLMBCOA_02290	3.43e-179	icaB	-	-	G	-	-	-	Polysaccharide deacetylase
HDLMBCOA_02292	1.42e-57	-	-	-	S	-	-	-	Bacteriophage holin
HDLMBCOA_02293	4.55e-64	-	-	-	-	-	-	-	-
HDLMBCOA_02294	1.12e-250	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HDLMBCOA_02296	2.25e-95	-	-	-	S	-	-	-	Protein of unknown function (DUF1617)
HDLMBCOA_02297	0.0	-	-	-	LM	-	-	-	DNA recombination
HDLMBCOA_02298	2.29e-81	-	-	-	-	-	-	-	-
HDLMBCOA_02299	0.0	-	-	-	D	-	-	-	domain protein
HDLMBCOA_02300	3.76e-32	-	-	-	-	-	-	-	-
HDLMBCOA_02301	1.42e-83	-	-	-	-	-	-	-	-
HDLMBCOA_02302	3.68e-102	-	-	-	S	-	-	-	Phage tail tube protein, TTP
HDLMBCOA_02303	4.08e-71	-	-	-	-	-	-	-	-
HDLMBCOA_02304	9.24e-116	-	-	-	-	-	-	-	-
HDLMBCOA_02305	9.63e-68	-	-	-	-	-	-	-	-
HDLMBCOA_02306	5.01e-69	-	-	-	-	-	-	-	-
HDLMBCOA_02308	2.08e-222	-	-	-	S	-	-	-	Phage major capsid protein E
HDLMBCOA_02309	4.9e-65	-	-	-	-	-	-	-	-
HDLMBCOA_02312	3.05e-41	-	-	-	-	-	-	-	-
HDLMBCOA_02313	0.0	-	-	-	S	-	-	-	Phage Mu protein F like protein
HDLMBCOA_02314	0.0	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
HDLMBCOA_02315	4.2e-304	-	-	-	S	-	-	-	Terminase-like family
HDLMBCOA_02316	8.11e-97	-	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
HDLMBCOA_02318	6.06e-29	-	-	-	-	-	-	-	-
HDLMBCOA_02324	0.0	-	-	-	S	-	-	-	Pfam Methyltransferase
HDLMBCOA_02325	5.83e-176	-	-	-	N	-	-	-	Cell shape-determining protein MreB
HDLMBCOA_02326	9.83e-137	-	-	-	N	-	-	-	Cell shape-determining protein MreB
HDLMBCOA_02327	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
HDLMBCOA_02328	2.78e-273	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HDLMBCOA_02329	3.21e-155	-	-	-	-	-	-	-	-
HDLMBCOA_02330	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HDLMBCOA_02331	1.07e-213	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
HDLMBCOA_02332	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HDLMBCOA_02333	9.87e-238	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
HDLMBCOA_02334	3.26e-293	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HDLMBCOA_02335	5.42e-142	-	-	-	GK	-	-	-	ROK family
HDLMBCOA_02336	5.91e-208	-	-	-	P	-	-	-	Major Facilitator Superfamily
HDLMBCOA_02337	1.98e-184	lipA	-	-	I	-	-	-	Carboxylesterase family
HDLMBCOA_02338	4.55e-141	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HDLMBCOA_02339	1.78e-201	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HDLMBCOA_02340	4.53e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HDLMBCOA_02341	2.07e-123	-	-	-	-	-	-	-	-
HDLMBCOA_02342	6.36e-237	-	-	-	P	ko:K06901	-	ko00000,ko02000	secondary active sulfate transmembrane transporter activity
HDLMBCOA_02343	3.26e-119	-	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Phosphoribosyl transferase domain
HDLMBCOA_02355	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HDLMBCOA_02356	0.0	pbg5	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HDLMBCOA_02357	6.7e-74	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
HDLMBCOA_02358	1.86e-64	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HDLMBCOA_02359	6.37e-169	gntR	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
HDLMBCOA_02360	1.4e-181	epsV	-	-	S	-	-	-	glycosyl transferase family 2
HDLMBCOA_02361	1.75e-156	pgm7	-	-	G	-	-	-	Phosphoglycerate mutase family
HDLMBCOA_02362	7.63e-107	-	-	-	-	-	-	-	-
HDLMBCOA_02363	5.06e-196	-	-	-	S	-	-	-	hydrolase
HDLMBCOA_02364	2.05e-233	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HDLMBCOA_02365	2.8e-204	-	-	-	EG	-	-	-	EamA-like transporter family
HDLMBCOA_02366	3e-150	serA1	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HDLMBCOA_02367	9.26e-56	serA1	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HDLMBCOA_02368	3.78e-132	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HDLMBCOA_02369	0.0	-	-	-	-	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	-
HDLMBCOA_02370	1.17e-101	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HDLMBCOA_02371	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HDLMBCOA_02372	0.0	-	-	-	M	-	-	-	Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
HDLMBCOA_02373	4.3e-44	-	-	-	-	-	-	-	-
HDLMBCOA_02374	6.01e-165	aroC1	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Type I 3-dehydroquinase
HDLMBCOA_02375	0.0	ycaM	-	-	E	-	-	-	amino acid
HDLMBCOA_02376	2.45e-101	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HDLMBCOA_02377	1.66e-211	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
HDLMBCOA_02378	2.95e-207	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HDLMBCOA_02379	6.19e-208	-	-	-	K	-	-	-	Transcriptional regulator
HDLMBCOA_02381	1.45e-161	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HDLMBCOA_02382	5.06e-194	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HDLMBCOA_02383	8.49e-144	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HDLMBCOA_02384	4.03e-125	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HDLMBCOA_02385	7.94e-114	ykuL	-	-	S	-	-	-	(CBS) domain
HDLMBCOA_02386	2.29e-112	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HDLMBCOA_02387	6.72e-289	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HDLMBCOA_02388	2.31e-202	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
HDLMBCOA_02389	1.88e-75	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HDLMBCOA_02390	1.6e-96	-	-	-	-	-	-	-	-
HDLMBCOA_02391	9.11e-106	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HDLMBCOA_02392	8.96e-275	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HDLMBCOA_02393	5.44e-232	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HDLMBCOA_02394	1.59e-210	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HDLMBCOA_02395	2.44e-65	-	-	-	S	ko:K09004	-	ko00000	DsrE/DsrF-like family
HDLMBCOA_02396	2.21e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
HDLMBCOA_02397	2.06e-205	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HDLMBCOA_02398	2.57e-224	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
HDLMBCOA_02399	6.2e-242	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
HDLMBCOA_02400	1.97e-72	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
HDLMBCOA_02401	1.5e-108	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
HDLMBCOA_02402	3.03e-27	-	-	-	-	ko:K02671	-	ko00000,ko02035,ko02044	-
HDLMBCOA_02403	6.46e-113	-	-	-	S	-	-	-	Prokaryotic N-terminal methylation motif
HDLMBCOA_02405	3.16e-236	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
HDLMBCOA_02406	4.7e-282	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HDLMBCOA_02407	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HDLMBCOA_02408	1.66e-150	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HDLMBCOA_02409	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HDLMBCOA_02410	1.96e-116	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
HDLMBCOA_02411	7.18e-189	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HDLMBCOA_02412	4.69e-151	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
HDLMBCOA_02413	1.39e-150	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
HDLMBCOA_02414	5.16e-141	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HDLMBCOA_02415	2e-98	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	general stress protein
HDLMBCOA_02416	1.11e-84	-	-	-	-	-	-	-	-
HDLMBCOA_02417	4.92e-79	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HDLMBCOA_02418	1.99e-197	mrsA1	1.8.4.11	-	O	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HDLMBCOA_02420	2.57e-226	-	-	-	K	ko:K01990	-	ko00000,ko00002,ko02000	LytTr DNA-binding domain
HDLMBCOA_02421	3.06e-201	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HDLMBCOA_02422	1.16e-160	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
HDLMBCOA_02424	2.8e-166	XK27_06930	-	-	V	ko:K01421	-	ko00000	domain protein
HDLMBCOA_02425	8.07e-164	XK27_06930	-	-	V	ko:K01421	-	ko00000	domain protein
HDLMBCOA_02426	3.55e-72	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HDLMBCOA_02427	2.07e-155	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HDLMBCOA_02428	5.45e-162	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HDLMBCOA_02429	0.0	ugpB	-	-	G	ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HDLMBCOA_02430	6.16e-193	ugpE	-	-	G	ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HDLMBCOA_02431	1.13e-221	ugpA	-	-	U	ko:K02025,ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HDLMBCOA_02432	1.24e-259	ugpC	3.6.3.20	-	E	ko:K05816,ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the ABC transporter superfamily
HDLMBCOA_02433	2.16e-109	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HDLMBCOA_02434	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
HDLMBCOA_02435	3.03e-193	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HDLMBCOA_02436	5.04e-176	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HDLMBCOA_02437	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HDLMBCOA_02438	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HDLMBCOA_02439	2.95e-160	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
HDLMBCOA_02440	3.03e-122	mraW1	-	-	J	-	-	-	Putative rRNA methylase
HDLMBCOA_02441	2.68e-39	-	-	-	-	-	-	-	-
HDLMBCOA_02442	0.0	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HDLMBCOA_02443	0.0	tagE2	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HDLMBCOA_02444	8.9e-96	ywnA	-	-	K	-	-	-	Transcriptional regulator
HDLMBCOA_02445	1.49e-155	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDLMBCOA_02446	4.02e-301	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HDLMBCOA_02447	2.71e-151	-	-	-	-	-	-	-	-
HDLMBCOA_02448	5.9e-57	-	-	-	-	-	-	-	-
HDLMBCOA_02449	1.55e-55	-	-	-	-	-	-	-	-
HDLMBCOA_02450	6.88e-311	hpk2	-	-	T	-	-	-	Histidine kinase
HDLMBCOA_02451	4.47e-164	rrp2	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
HDLMBCOA_02452	1.4e-64	-	-	-	-	-	-	-	-
HDLMBCOA_02453	2.29e-166	yidA	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HDLMBCOA_02454	7.37e-308	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDLMBCOA_02455	4.42e-71	-	-	-	-	-	-	-	-
HDLMBCOA_02456	2.87e-56	-	-	-	-	-	-	-	-
HDLMBCOA_02457	1.76e-236	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HDLMBCOA_02458	0.0	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
HDLMBCOA_02459	1.49e-63	-	-	-	-	-	-	-	-
HDLMBCOA_02460	2.04e-158	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HDLMBCOA_02461	1.17e-135	-	-	-	K	-	-	-	transcriptional regulator
HDLMBCOA_02462	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
HDLMBCOA_02463	6.83e-138	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HDLMBCOA_02464	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
HDLMBCOA_02465	4.32e-294	vex3	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HDLMBCOA_02466	4.87e-156	vex2	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HDLMBCOA_02467	9.28e-171	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HDLMBCOA_02468	2.75e-156	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HDLMBCOA_02469	6.46e-79	-	-	-	M	-	-	-	Lysin motif
HDLMBCOA_02470	1.27e-219	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HDLMBCOA_02471	4.71e-81	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HDLMBCOA_02472	2.03e-271	yttB	-	-	EGP	-	-	-	Major Facilitator
HDLMBCOA_02473	0.0	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HDLMBCOA_02474	1.18e-114	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
HDLMBCOA_02475	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
HDLMBCOA_02476	2.97e-76	-	-	-	-	-	-	-	-
HDLMBCOA_02477	2.61e-96	hsp2	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HDLMBCOA_02478	3.65e-78	-	-	-	-	-	-	-	-
HDLMBCOA_02479	1.7e-118	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HDLMBCOA_02480	8.05e-179	rrp8	-	-	K	-	-	-	LytTr DNA-binding domain
HDLMBCOA_02481	4.85e-151	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HDLMBCOA_02482	1.01e-177	-	-	-	-	-	-	-	-
HDLMBCOA_02483	5.55e-116	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HDLMBCOA_02484	3.53e-169	-	-	-	K	-	-	-	Transcriptional regulator
HDLMBCOA_02485	4.74e-208	-	-	-	S	-	-	-	Putative esterase
HDLMBCOA_02486	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HDLMBCOA_02487	5.31e-285	-	-	-	M	-	-	-	Glycosyl transferases group 1
HDLMBCOA_02488	1.38e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HDLMBCOA_02489	2.34e-63	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HDLMBCOA_02490	2.12e-98	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
HDLMBCOA_02491	1.09e-55	-	-	-	S	-	-	-	zinc-ribbon domain
HDLMBCOA_02492	3.77e-24	-	-	-	-	-	-	-	-
HDLMBCOA_02493	5.88e-202	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HDLMBCOA_02494	1.02e-102	uspA3	-	-	T	-	-	-	universal stress protein
HDLMBCOA_02495	5.87e-166	-	-	-	K	ko:K03710	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HDLMBCOA_02496	1.49e-112	-	2.7.1.191	-	K	ko:K02745,ko:K02794,ko:K10984	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HDLMBCOA_02497	5.2e-185	-	-	-	G	ko:K02746,ko:K10985	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HDLMBCOA_02498	3.82e-188	agaD	-	-	G	ko:K02747,ko:K02796,ko:K10986	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
HDLMBCOA_02499	1.63e-95	-	-	-	G	ko:K02744	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HDLMBCOA_02500	1.42e-144	mleP3	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HDLMBCOA_02501	3.82e-47	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
HDLMBCOA_02502	9.73e-99	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
HDLMBCOA_02503	4.75e-104	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HDLMBCOA_02504	1.39e-188	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HDLMBCOA_02505	2.33e-103	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HDLMBCOA_02506	7.96e-127	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HDLMBCOA_02507	4.38e-222	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HDLMBCOA_02508	2.06e-194	rlrG	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
HDLMBCOA_02509	0.0	tagE5	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
HDLMBCOA_02510	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HDLMBCOA_02512	9.92e-88	-	-	-	M	-	-	-	LysM domain
HDLMBCOA_02513	1.6e-119	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
HDLMBCOA_02514	9.97e-214	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDLMBCOA_02515	7.88e-269	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HDLMBCOA_02516	6.27e-166	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HDLMBCOA_02517	9.52e-72	cmd	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
HDLMBCOA_02518	4.77e-100	yphH	-	-	S	-	-	-	Cupin domain
HDLMBCOA_02519	5.19e-103	-	-	-	K	-	-	-	transcriptional regulator, MerR family
HDLMBCOA_02520	1.46e-299	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HDLMBCOA_02521	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HDLMBCOA_02522	1.74e-156	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDLMBCOA_02524	2.93e-151	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HDLMBCOA_02525	3.18e-141	thgA3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HDLMBCOA_02526	1.03e-150	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HDLMBCOA_02528	4.86e-111	-	-	-	-	-	-	-	-
HDLMBCOA_02529	1.04e-110	yvbK	-	-	K	-	-	-	GNAT family
HDLMBCOA_02530	9.76e-50	-	-	-	-	-	-	-	-
HDLMBCOA_02531	2.81e-64	-	-	-	-	-	-	-	-
HDLMBCOA_02532	7.44e-143	pgm8	-	-	G	-	-	-	Histidine phosphatase superfamily (branch 1)
HDLMBCOA_02533	1.21e-41	ygbF	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
HDLMBCOA_02534	0.0	-	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 85
HDLMBCOA_02535	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HDLMBCOA_02536	2.44e-267	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HDLMBCOA_02537	0.0	malS	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Glycogen debranching enzyme, glucanotransferase domain
HDLMBCOA_02538	2.91e-190	malA	-	-	S	-	-	-	maltodextrose utilization protein MalA
HDLMBCOA_02539	2.83e-206	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HDLMBCOA_02540	3.74e-302	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HDLMBCOA_02541	9.45e-299	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HDLMBCOA_02542	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
HDLMBCOA_02543	1.83e-231	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HDLMBCOA_02544	2.65e-245	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
HDLMBCOA_02545	4e-172	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HDLMBCOA_02546	6.76e-75	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
HDLMBCOA_02547	2.75e-131	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
HDLMBCOA_02548	1.58e-238	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
HDLMBCOA_02549	1.93e-242	dhaK2	2.7.1.28, 2.7.1.29, 4.6.1.15	-	G	ko:K00863	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	ko00000,ko00001,ko00002,ko01000	Dak1 domain
HDLMBCOA_02550	1.85e-121	XK27_02085	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDLMBCOA_02551	2.04e-99	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
HDLMBCOA_02552	0.0	etfA	1.3.1.108	-	C	ko:K03522,ko:K22432	-	ko00000,ko01000,ko04147	Electron transfer flavoprotein FAD-binding domain
HDLMBCOA_02553	8.03e-151	-	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
HDLMBCOA_02554	0.0	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
HDLMBCOA_02555	6.03e-218	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HDLMBCOA_02556	1.01e-184	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
HDLMBCOA_02557	6.67e-30	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HDLMBCOA_02558	1.66e-96	-	-	-	-	-	-	-	-
HDLMBCOA_02559	1.26e-70	-	-	-	-	-	-	-	-
HDLMBCOA_02560	1.37e-83	-	-	-	K	-	-	-	Helix-turn-helix domain
HDLMBCOA_02561	3.87e-141	XK27_07075	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HDLMBCOA_02562	5.79e-46	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HDLMBCOA_02563	3.11e-134	-	-	-	L	-	-	-	Helix-turn-helix domain
HDLMBCOA_02564	4.73e-206	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HDLMBCOA_02565	5.06e-297	yceJ	-	-	EGP	ko:K08221	-	ko00000,ko02000	transporter
HDLMBCOA_02566	5.56e-262	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
HDLMBCOA_02567	2.09e-60	-	-	-	S	-	-	-	MORN repeat
HDLMBCOA_02568	0.0	XK27_09800	-	-	I	-	-	-	Acyltransferase family
HDLMBCOA_02569	1.81e-50	ydaS	-	-	S	-	-	-	Transglycosylase associated protein
HDLMBCOA_02570	1.37e-116	-	-	-	-	-	-	-	-
HDLMBCOA_02571	5.74e-32	-	-	-	-	-	-	-	-
HDLMBCOA_02572	1.1e-93	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HDLMBCOA_02573	1.04e-94	asp2	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HDLMBCOA_02574	2.02e-192	yisK	3.7.1.5, 4.1.1.68	-	Q	ko:K05921,ko:K16164	ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Fumarylacetoacetate (FAA) hydrolase family
HDLMBCOA_02575	1.22e-210	yjdB	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HDLMBCOA_02576	4.46e-63	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HDLMBCOA_02577	2.66e-132	-	-	-	G	-	-	-	Glycogen debranching enzyme
HDLMBCOA_02578	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
HDLMBCOA_02579	8.07e-284	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HDLMBCOA_02580	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HDLMBCOA_02581	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HDLMBCOA_02582	6.68e-75	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HDLMBCOA_02583	4.09e-131	-	-	-	K	-	-	-	FR47-like protein
HDLMBCOA_02584	8.44e-163	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
HDLMBCOA_02585	9.39e-278	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
HDLMBCOA_02586	1.53e-241	-	-	-	-	-	-	-	-
HDLMBCOA_02587	5.03e-180	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HDLMBCOA_02588	5.06e-68	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HDLMBCOA_02589	9.54e-209	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HDLMBCOA_02590	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HDLMBCOA_02591	4.95e-44	-	-	-	L	-	-	-	leucine-zipper of insertion element IS481
HDLMBCOA_02592	9.05e-55	-	-	-	-	-	-	-	-
HDLMBCOA_02593	6.71e-284	-	-	-	L	-	-	-	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HDLMBCOA_02594	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HDLMBCOA_02595	1.38e-254	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
HDLMBCOA_02596	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HDLMBCOA_02597	1.3e-134	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HDLMBCOA_02598	4.3e-106	-	-	-	K	-	-	-	Transcriptional regulator
HDLMBCOA_02600	0.0	-	-	-	C	-	-	-	FMN_bind
HDLMBCOA_02601	1.37e-220	-	-	-	K	-	-	-	Transcriptional regulator
HDLMBCOA_02602	3.8e-124	-	-	-	K	-	-	-	Helix-turn-helix domain
HDLMBCOA_02603	2.49e-178	-	-	-	K	-	-	-	sequence-specific DNA binding
HDLMBCOA_02604	2.48e-63	-	-	-	S	-	-	-	AAA domain
HDLMBCOA_02605	9.7e-34	-	-	-	S	-	-	-	AAA domain
HDLMBCOA_02606	1.42e-08	-	-	-	-	-	-	-	-
HDLMBCOA_02607	5.66e-55	-	-	-	M	-	-	-	MucBP domain
HDLMBCOA_02608	0.0	-	-	-	M	-	-	-	MucBP domain
HDLMBCOA_02609	1.39e-118	XK27_09665	-	-	G	ko:K15640	-	ko00000	Phosphoglycerate mutase family
HDLMBCOA_02610	1.04e-134	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDLMBCOA_02611	1.33e-84	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HDLMBCOA_02612	2.92e-188	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
HDLMBCOA_02614	3.69e-35	-	-	-	-	-	-	-	-
HDLMBCOA_02615	1.14e-199	repA	-	-	S	-	-	-	Replication initiator protein A
HDLMBCOA_02616	9.37e-159	-	-	-	S	-	-	-	Fic/DOC family
HDLMBCOA_02617	5.76e-53	-	-	-	-	-	-	-	-
HDLMBCOA_02618	9.79e-37	-	-	-	-	-	-	-	-
HDLMBCOA_02619	0.0	traA	-	-	L	-	-	-	MobA MobL family protein
HDLMBCOA_02620	1.86e-45	-	-	-	-	-	-	-	-
HDLMBCOA_02621	1.32e-125	-	-	-	-	-	-	-	-
HDLMBCOA_02622	2.57e-67	-	-	-	S	-	-	-	Cag pathogenicity island, type IV secretory system
HDLMBCOA_02623	8.94e-70	-	-	-	-	-	-	-	-
HDLMBCOA_02624	5.23e-151	-	-	-	-	-	-	-	-
HDLMBCOA_02625	0.0	-	-	-	U	-	-	-	AAA-like domain
HDLMBCOA_02626	0.0	-	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
HDLMBCOA_02627	3.13e-263	-	-	-	M	-	-	-	CHAP domain
HDLMBCOA_02628	7.51e-119	-	-	-	-	-	-	-	-
HDLMBCOA_02629	6.87e-71	-	-	-	CO	-	-	-	COG0526, thiol-disulfide isomerase and thioredoxins
HDLMBCOA_02630	7.13e-100	-	-	-	-	-	-	-	-
HDLMBCOA_02632	0.0	traK	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	COG3505 Type IV secretory pathway, VirD4 components
HDLMBCOA_02633	1e-78	-	-	-	-	-	-	-	-
HDLMBCOA_02634	9.8e-198	-	-	-	-	-	-	-	-
HDLMBCOA_02635	1.16e-84	-	-	-	-	-	-	-	-
HDLMBCOA_02636	0.0	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HDLMBCOA_02637	3.6e-42	-	-	-	-	-	-	-	-
HDLMBCOA_02638	1.91e-242	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HDLMBCOA_02639	2.4e-137	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HDLMBCOA_02640	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HDLMBCOA_02641	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HDLMBCOA_02642	3.82e-228	-	-	-	K	-	-	-	Transcriptional regulator
HDLMBCOA_02643	3.21e-215	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
HDLMBCOA_02644	1.27e-103	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HDLMBCOA_02645	9.17e-126	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HDLMBCOA_02646	5.12e-42	-	-	-	S	-	-	-	YozE SAM-like fold
HDLMBCOA_02647	4.19e-203	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HDLMBCOA_02648	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HDLMBCOA_02649	2.06e-174	-	-	-	M	-	-	-	Glycosyl transferase family group 2
HDLMBCOA_02650	4.93e-115	-	-	-	M	-	-	-	Glycosyl transferase family group 2
HDLMBCOA_02651	3.22e-87	-	-	-	-	-	-	-	-
HDLMBCOA_02652	0.0	gshR1	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HDLMBCOA_02653	1.48e-98	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HDLMBCOA_02654	3.29e-121	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HDLMBCOA_02655	0.0	tarL	2.7.8.14, 2.7.8.47	-	H	ko:K18704	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HDLMBCOA_02656	1.13e-270	tarK	2.7.8.14, 2.7.8.46, 2.7.8.47	-	H	ko:K18704,ko:K21592	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HDLMBCOA_02657	6.51e-247	tarJ	1.1.1.137, 1.1.1.405	-	E	ko:K05352,ko:K21680	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
HDLMBCOA_02658	2.13e-151	tarI	2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21030	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
HDLMBCOA_02659	6.09e-35	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
HDLMBCOA_02660	2.78e-158	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
HDLMBCOA_02661	5.21e-180	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
HDLMBCOA_02662	1.88e-192	livM	-	-	E	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HDLMBCOA_02663	9.73e-197	livH	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HDLMBCOA_02664	1.04e-269	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
HDLMBCOA_02666	1.15e-43	-	-	-	-	-	-	-	-
HDLMBCOA_02667	2.81e-167	zmp3	-	-	O	-	-	-	Zinc-dependent metalloprotease
HDLMBCOA_02668	7.71e-71	gtcA3	-	-	S	-	-	-	GtrA-like protein
HDLMBCOA_02669	5.9e-12	gtcA3	-	-	S	-	-	-	GtrA-like protein
HDLMBCOA_02670	3.35e-157	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HDLMBCOA_02671	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HDLMBCOA_02672	1.18e-94	usp2	-	-	T	-	-	-	Belongs to the universal stress protein A family
HDLMBCOA_02673	7.03e-62	-	-	-	-	-	-	-	-
HDLMBCOA_02674	1.81e-150	-	-	-	S	-	-	-	SNARE associated Golgi protein
HDLMBCOA_02675	8.58e-65	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
HDLMBCOA_02676	7.89e-124	-	-	-	P	-	-	-	Cadmium resistance transporter
HDLMBCOA_02677	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDLMBCOA_02678	0.0	-	-	-	P	-	-	-	Concanavalin A-like lectin/glucanases superfamily
HDLMBCOA_02679	2.03e-84	-	-	-	-	-	-	-	-
HDLMBCOA_02680	1.93e-205	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HDLMBCOA_02681	1.21e-73	-	-	-	-	-	-	-	-
HDLMBCOA_02682	1.24e-194	-	-	-	K	-	-	-	Helix-turn-helix domain
HDLMBCOA_02683	3.91e-100	pts23A	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HDLMBCOA_02684	3e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HDLMBCOA_02685	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HDLMBCOA_02686	1.06e-49	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HDLMBCOA_02687	1.31e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HDLMBCOA_02688	5.39e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HDLMBCOA_02689	5e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HDLMBCOA_02690	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HDLMBCOA_02691	2.79e-316	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HDLMBCOA_02692	8.32e-227	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
HDLMBCOA_02693	2.48e-276	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HDLMBCOA_02694	1.32e-63	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HDLMBCOA_02695	9.91e-289	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HDLMBCOA_02696	5.87e-256	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HDLMBCOA_02697	2.62e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HDLMBCOA_02698	9.47e-137	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HDLMBCOA_02699	2.83e-114	-	-	-	-	-	-	-	-
HDLMBCOA_02700	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HDLMBCOA_02701	3.06e-90	-	-	-	-	-	-	-	-
HDLMBCOA_02702	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HDLMBCOA_02703	5.38e-77	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HDLMBCOA_02704	1.37e-148	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HDLMBCOA_02705	1.93e-209	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HDLMBCOA_02706	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HDLMBCOA_02707	4.3e-124	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HDLMBCOA_02708	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HDLMBCOA_02709	1.07e-103	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
HDLMBCOA_02710	2.02e-83	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HDLMBCOA_02712	7.72e-57	yabO	-	-	J	-	-	-	S4 domain protein
HDLMBCOA_02713	0.0	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HDLMBCOA_02714	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HDLMBCOA_02715	1.43e-129	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HDLMBCOA_02716	1.61e-225	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HDLMBCOA_02717	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HDLMBCOA_02718	4.87e-148	-	-	-	S	-	-	-	(CBS) domain
HDLMBCOA_02719	1.17e-100	-	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside 2-deoxyribosyltransferase
HDLMBCOA_02720	4.43e-129	-	-	-	-	-	-	-	-
HDLMBCOA_02721	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HDLMBCOA_02722	9.9e-144	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HDLMBCOA_02723	6.59e-227	-	-	-	K	-	-	-	LysR substrate binding domain
HDLMBCOA_02724	2.41e-233	-	-	-	M	-	-	-	Peptidase family S41
HDLMBCOA_02725	1.05e-272	-	-	-	-	-	-	-	-
HDLMBCOA_02726	1.03e-240	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
HDLMBCOA_02727	0.0	yhaN	-	-	L	-	-	-	AAA domain
HDLMBCOA_02728	1.82e-295	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
HDLMBCOA_02729	9.94e-71	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HDLMBCOA_02730	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HDLMBCOA_02731	2.43e-18	-	-	-	-	-	-	-	-
HDLMBCOA_02732	2.07e-102	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HDLMBCOA_02733	5.58e-271	arcT	-	-	E	-	-	-	Aminotransferase
HDLMBCOA_02734	2.42e-65	argO	-	-	S	ko:K06895	-	ko00000,ko02000	LysE type translocator
HDLMBCOA_02735	1.06e-23	argO	-	-	S	ko:K06895	-	ko00000,ko02000	LysE type translocator
HDLMBCOA_02736	5.33e-41	mleP3	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HDLMBCOA_02737	9.01e-155	-	-	-	S	-	-	-	Membrane
HDLMBCOA_02738	8.02e-258	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HDLMBCOA_02739	1.45e-126	ywjB	-	-	H	-	-	-	RibD C-terminal domain
HDLMBCOA_02740	3.31e-237	iunH3	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
HDLMBCOA_02741	2.27e-116	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
HDLMBCOA_02742	7.14e-157	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDLMBCOA_02743	4.88e-240	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HDLMBCOA_02744	5.35e-123	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
HDLMBCOA_02745	3.41e-295	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HDLMBCOA_02746	3.82e-188	-	-	-	KT	-	-	-	helix_turn_helix, mercury resistance
HDLMBCOA_02747	1.95e-149	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HDLMBCOA_02748	1.04e-120	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HDLMBCOA_02749	1.57e-184	-	-	-	S	-	-	-	Peptidase_C39 like family
HDLMBCOA_02750	3.6e-228	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HDLMBCOA_02751	1.27e-143	-	-	-	-	-	-	-	-
HDLMBCOA_02752	3.47e-306	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HDLMBCOA_02753	8.02e-110	-	-	-	S	-	-	-	Pfam:DUF3816
HDLMBCOA_02754	0.0	pts26BCA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HDLMBCOA_02755	0.0	malL	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HDLMBCOA_02756	6.12e-232	purR2	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
HDLMBCOA_02757	3.73e-263	-	-	-	S	-	-	-	DUF218 domain
HDLMBCOA_02758	2.44e-165	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
HDLMBCOA_02759	2.93e-151	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDLMBCOA_02760	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HDLMBCOA_02761	3.62e-100	-	-	-	-	-	-	-	-
HDLMBCOA_02762	2.69e-194	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
HDLMBCOA_02763	3.54e-190	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HDLMBCOA_02764	2.24e-116	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HDLMBCOA_02765	0.0	mngB	3.2.1.170	GH38	G	ko:K15524	-	ko00000,ko01000	Glycosyl hydrolases family 38 N-terminal domain
HDLMBCOA_02766	6.69e-155	fptC	-	-	U	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase system, EIIC
HDLMBCOA_02767	2.52e-35	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HDLMBCOA_02768	5.55e-22	-	-	-	G	ko:K11203	-	ko00000,ko00002,ko02000	PTS system, fructose subfamily
HDLMBCOA_02769	4.19e-79	-	-	-	GKT	ko:K02538	-	ko00000,ko03000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HDLMBCOA_02770	1.23e-80	ypgQ	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HDLMBCOA_02771	6.32e-08	-	3.3.1.1	-	H	ko:K01251	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	adenosylhomocysteinase activity
HDLMBCOA_02772	7.07e-106	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
HDLMBCOA_02773	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HDLMBCOA_02774	4.4e-217	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleotide reductase, small chain
HDLMBCOA_02775	9.42e-232	-	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleotide reductase, small chain
HDLMBCOA_02776	6.6e-147	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HDLMBCOA_02777	4.34e-138	-	-	-	L	-	-	-	Resolvase, N terminal domain
HDLMBCOA_02778	1.29e-205	XK27_10395	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HDLMBCOA_02780	1.23e-186	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
HDLMBCOA_02781	4.36e-48	-	-	-	L	-	-	-	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HDLMBCOA_02782	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HDLMBCOA_02783	1.4e-69	repA	-	-	S	-	-	-	Replication initiator protein A
HDLMBCOA_02784	4.78e-42	-	-	-	-	-	-	-	-
HDLMBCOA_02785	8.01e-88	-	-	-	S	-	-	-	protein conserved in bacteria
HDLMBCOA_02786	7.81e-56	-	-	-	-	-	-	-	-
HDLMBCOA_02787	9.79e-37	-	-	-	-	-	-	-	-
HDLMBCOA_02788	1.85e-139	traA	-	-	L	-	-	-	MobA MobL family protein
HDLMBCOA_02789	4.2e-135	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HDLMBCOA_02790	1.05e-173	plnD	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HDLMBCOA_02791	8.15e-167	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HDLMBCOA_02792	1.93e-31	plnF	-	-	-	-	-	-	-
HDLMBCOA_02793	2.59e-19	-	-	-	-	-	-	-	-
HDLMBCOA_02794	1.65e-199	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HDLMBCOA_02795	1.27e-277	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HDLMBCOA_02796	1.17e-306	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
HDLMBCOA_02797	1.83e-140	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HDLMBCOA_02798	8.02e-152	plnU	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HDLMBCOA_02799	1.86e-143	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HDLMBCOA_02800	1.59e-145	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HDLMBCOA_02801	4.23e-64	axe	-	-	K	ko:K21498	-	ko00000,ko02048	Helix-turn-helix XRE-family like proteins
HDLMBCOA_02802	0.0	-	-	-	L	-	-	-	DNA helicase
HDLMBCOA_02803	8.34e-181	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
HDLMBCOA_02804	2.35e-243	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HDLMBCOA_02805	2.69e-166	-	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
HDLMBCOA_02806	5.06e-82	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
HDLMBCOA_02807	1.04e-136	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HDLMBCOA_02808	9.55e-243	-	-	-	S	-	-	-	Cell surface protein
HDLMBCOA_02809	4.71e-81	-	-	-	-	-	-	-	-
HDLMBCOA_02810	0.0	-	-	-	-	-	-	-	-
HDLMBCOA_02811	5.98e-217	XK27_00670	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HDLMBCOA_02812	1.01e-198	WQ51_06230	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HDLMBCOA_02813	4.21e-150	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HDLMBCOA_02814	0.0	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HDLMBCOA_02815	3.29e-153	ydgI3	-	-	C	-	-	-	Nitroreductase family
HDLMBCOA_02816	2.21e-154	yceE	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HDLMBCOA_02817	5.85e-204	ccpB	-	-	K	-	-	-	lacI family
HDLMBCOA_02818	7.39e-121	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HDLMBCOA_02819	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HDLMBCOA_02820	4.08e-18	-	-	-	C	-	-	-	Flavodoxin
HDLMBCOA_02821	1e-62	adhR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HDLMBCOA_02822	2.66e-38	-	-	-	-	-	-	-	-
HDLMBCOA_02823	6.88e-151	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
HDLMBCOA_02824	1.43e-57	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
HDLMBCOA_02825	1.14e-244	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
HDLMBCOA_02826	1.74e-68	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
HDLMBCOA_02827	3.55e-91	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HDLMBCOA_02828	1.99e-190	-	-	-	T	-	-	-	diguanylate cyclase
HDLMBCOA_02829	1.44e-52	-	-	-	T	-	-	-	diguanylate cyclase
HDLMBCOA_02830	6.68e-156	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
HDLMBCOA_02831	1.24e-120	-	-	-	-	-	-	-	-
HDLMBCOA_02832	2.74e-210	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HDLMBCOA_02833	1.58e-72	nudA	-	-	S	-	-	-	ASCH
HDLMBCOA_02834	1.15e-137	-	-	-	S	-	-	-	SdpI/YhfL protein family
HDLMBCOA_02835	9.44e-76	-	-	-	M	-	-	-	Lysin motif
HDLMBCOA_02836	2.18e-99	-	-	-	M	-	-	-	LysM domain
HDLMBCOA_02837	2.1e-99	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HDLMBCOA_02838	7.8e-238	-	-	-	GM	-	-	-	Male sterility protein
HDLMBCOA_02839	0.0	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HDLMBCOA_02840	0.0	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDLMBCOA_02841	7.47e-70	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HDLMBCOA_02842	4.28e-253	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
HDLMBCOA_02843	3.53e-160	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HDLMBCOA_02844	1.27e-222	-	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
HDLMBCOA_02845	7.05e-219	cpsY	-	-	K	-	-	-	Transcriptional regulator, LysR family
HDLMBCOA_02846	5.13e-292	XK27_05470	-	-	E	-	-	-	Methionine synthase
HDLMBCOA_02848	2.25e-207	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HDLMBCOA_02849	1.01e-175	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HDLMBCOA_02850	8.11e-203	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
HDLMBCOA_02851	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HDLMBCOA_02852	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HDLMBCOA_02853	1.5e-227	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
HDLMBCOA_02854	6.84e-121	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HDLMBCOA_02855	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HDLMBCOA_02856	2.1e-216	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HDLMBCOA_02857	6.02e-148	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
HDLMBCOA_02858	1.16e-72	-	-	-	-	-	-	-	-
HDLMBCOA_02859	5.45e-86	-	-	-	-	-	-	-	-
HDLMBCOA_02860	6.9e-129	-	-	-	K	-	-	-	Helix-turn-helix domain
HDLMBCOA_02861	1.27e-222	-	-	-	M	-	-	-	Peptidase family S41
HDLMBCOA_02862	1.15e-243	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HDLMBCOA_02863	7.81e-46	-	-	-	-	-	-	-	-
HDLMBCOA_02864	0.0	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HDLMBCOA_02865	4.68e-95	-	-	-	-	-	-	-	-
HDLMBCOA_02867	1.51e-293	traK	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	TraM recognition site of TraD and TraG
HDLMBCOA_02868	3.88e-87	-	-	-	-	-	-	-	-
HDLMBCOA_02869	1.13e-57	-	-	-	CO	-	-	-	COG0526, thiol-disulfide isomerase and thioredoxins
HDLMBCOA_02870	2.51e-75	-	-	-	-	-	-	-	-
HDLMBCOA_02871	7.88e-209	-	-	-	M	-	-	-	CHAP domain
HDLMBCOA_02872	1.65e-304	-	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
HDLMBCOA_02873	0.0	-	-	-	U	-	-	-	type IV secretory pathway VirB4
HDLMBCOA_02874	2.8e-256	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HDLMBCOA_02875	1.05e-275	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
HDLMBCOA_02876	1.74e-169	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HDLMBCOA_02877	6.23e-316	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HDLMBCOA_02878	6.91e-201	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HDLMBCOA_02879	4.48e-206	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HDLMBCOA_02880	5.04e-200	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
HDLMBCOA_02881	9.78e-190	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HDLMBCOA_02882	9.4e-179	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HDLMBCOA_02883	1.55e-150	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HDLMBCOA_02884	2.29e-64	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	positive regulation of macromolecule biosynthetic process
HDLMBCOA_02885	2.87e-71	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
HDLMBCOA_02886	2.55e-225	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HDLMBCOA_02887	6.26e-213	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HDLMBCOA_02888	2.41e-236	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HDLMBCOA_02889	1.13e-218	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HDLMBCOA_02890	6.37e-160	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HDLMBCOA_02891	2.04e-128	nox	-	-	C	-	-	-	NADH oxidase
HDLMBCOA_02892	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDLMBCOA_02893	9.68e-34	-	-	-	-	-	-	-	-
HDLMBCOA_02894	1.69e-97	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HDLMBCOA_02895	5.9e-46	-	-	-	-	-	-	-	-
HDLMBCOA_02896	1.6e-77	chpA	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
HDLMBCOA_02897	9.82e-243	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HDLMBCOA_02898	7.87e-214	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HDLMBCOA_02899	1.37e-290	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
HDLMBCOA_02900	3.82e-228	-	-	-	-	-	-	-	-
HDLMBCOA_02901	2.14e-171	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
HDLMBCOA_02902	1.12e-205	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
HDLMBCOA_02903	4.64e-92	-	-	-	F	-	-	-	DNA mismatch repair protein MutT
HDLMBCOA_02904	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HDLMBCOA_02905	2.11e-272	-	-	-	EGP	ko:K02030	-	ko00000,ko00002,ko02000	Drug resistance transporter Bcr CflA subfamily
HDLMBCOA_02906	5.1e-106	mutR	-	-	K	ko:K20373,ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
HDLMBCOA_02909	6.61e-77	-	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HDLMBCOA_02910	6.83e-99	-	-	-	S	ko:K06889	-	ko00000	X-Pro dipeptidyl-peptidase (S15 family)
HDLMBCOA_02911	1.56e-56	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDLMBCOA_02912	1.66e-214	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
HDLMBCOA_02913	7.99e-92	-	-	-	-	-	-	-	-
HDLMBCOA_02914	6.54e-168	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HDLMBCOA_02915	7.62e-222	-	-	-	C	-	-	-	C4-dicarboxylate transmembrane transporter activity
HDLMBCOA_02916	2.15e-151	-	-	-	GM	-	-	-	NAD(P)H-binding
HDLMBCOA_02917	3.23e-118	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HDLMBCOA_02918	6.7e-102	yphH	-	-	S	-	-	-	Cupin domain
HDLMBCOA_02919	3.55e-79	-	-	-	I	-	-	-	sulfurtransferase activity
HDLMBCOA_02920	3.83e-178	gdh	1.1.1.47, 1.1.1.53	-	IQ	ko:K00034,ko:K00038	ko00030,ko00140,ko01100,ko01120,ko01200,map00030,map00140,map01100,map01120,map01200	ko00000,ko00001,ko01000	reductase
HDLMBCOA_02921	2.4e-151	-	-	-	GM	-	-	-	NAD(P)H-binding
HDLMBCOA_02922	7.71e-276	-	-	-	-	-	-	-	-
HDLMBCOA_02923	1.85e-252	-	-	-	V	ko:K06147,ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HDLMBCOA_02924	5.53e-131	-	-	-	V	ko:K06147,ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HDLMBCOA_02925	2.49e-73	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HDLMBCOA_02926	1.09e-298	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HDLMBCOA_02928	2.78e-119	repE	-	-	K	-	-	-	Primase C terminal 1 (PriCT-1)
HDLMBCOA_02929	2.7e-79	-	-	-	D	-	-	-	AAA domain
HDLMBCOA_02931	1.84e-192	-	-	-	L	ko:K07482	-	ko00000	Integrase core domain
HDLMBCOA_02932	1.71e-94	cpsE	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
HDLMBCOA_02933	4.89e-70	-	-	-	L	-	-	-	recombinase activity
HDLMBCOA_02935	1.13e-89	-	-	-	D	ko:K19171	-	ko00000,ko02048	AAA domain
HDLMBCOA_02937	5.3e-115	-	-	-	KL	-	-	-	SNF2 family N-terminal domain
HDLMBCOA_02941	2.69e-35	-	-	-	-	-	-	-	-
HDLMBCOA_02943	2.03e-182	-	-	-	-	-	-	-	-
HDLMBCOA_02946	3.56e-152	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HDLMBCOA_02948	8.58e-71	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HDLMBCOA_02949	7.1e-81	-	-	-	S	-	-	-	Protein of unknown function (DUF2992)
HDLMBCOA_02950	1.03e-77	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
HDLMBCOA_02951	4.17e-55	-	-	-	K	-	-	-	prlF antitoxin for toxin YhaV_toxin
HDLMBCOA_02952	1.87e-139	-	-	-	L	-	-	-	Integrase
HDLMBCOA_02954	5.07e-40	-	-	-	-	-	-	-	-
HDLMBCOA_02955	9.34e-225	-	-	-	L	-	-	-	Initiator Replication protein
HDLMBCOA_02956	6.66e-115	-	-	-	-	-	-	-	-
HDLMBCOA_02957	1.39e-110	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HDLMBCOA_02959	3.39e-60	-	-	-	-	-	-	-	-
HDLMBCOA_02962	2.08e-30	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HDLMBCOA_02965	5.72e-27	-	-	-	-	-	-	-	-
HDLMBCOA_02966	8.82e-11	-	-	-	-	-	-	-	-
HDLMBCOA_02967	4.38e-36	-	-	-	S	-	-	-	Domain of unknown function (DUF771)
HDLMBCOA_02973	2.59e-52	-	-	-	S	-	-	-	Siphovirus Gp157
HDLMBCOA_02974	2e-194	-	-	-	S	-	-	-	helicase activity
HDLMBCOA_02975	2.32e-92	-	-	-	L	-	-	-	AAA domain
HDLMBCOA_02976	6.33e-28	-	-	-	-	-	-	-	-
HDLMBCOA_02977	1.1e-95	-	-	-	S	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
HDLMBCOA_02978	9.08e-166	-	-	-	S	ko:K06919	-	ko00000	Virulence-associated protein E
HDLMBCOA_02979	1.17e-47	-	-	-	S	-	-	-	VRR_NUC
HDLMBCOA_02984	2.08e-05	-	-	-	S	-	-	-	YopX protein
HDLMBCOA_02987	1.92e-42	-	-	-	-	-	-	-	-
HDLMBCOA_02988	4.54e-208	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HDLMBCOA_02989	1.85e-51	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HDLMBCOA_02990	1.98e-142	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
HDLMBCOA_02991	8.32e-226	-	4.1.1.52	-	S	ko:K22213	-	ko00000,ko01000	Amidohydrolase
HDLMBCOA_02992	1.24e-165	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HDLMBCOA_02993	8.08e-205	yicL	-	-	EG	-	-	-	EamA-like transporter family
HDLMBCOA_02994	1.21e-298	-	-	-	M	-	-	-	Collagen binding domain
HDLMBCOA_02995	0.0	-	-	-	I	-	-	-	acetylesterase activity
HDLMBCOA_02996	2.35e-231	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
HDLMBCOA_02997	1.48e-171	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
HDLMBCOA_02998	4.29e-50	-	-	-	-	-	-	-	-
HDLMBCOA_03000	1.61e-183	-	-	-	S	-	-	-	zinc-ribbon domain
HDLMBCOA_03001	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
HDLMBCOA_03003	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
HDLMBCOA_03004	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HDLMBCOA_03005	1.08e-221	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
HDLMBCOA_03006	0.0	treP	2.4.1.64	GH65	G	ko:K05342	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HDLMBCOA_03007	4.36e-202	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HDLMBCOA_03008	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HDLMBCOA_03009	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HDLMBCOA_03010	0.0	pbg9	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HDLMBCOA_03012	2.96e-118	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HDLMBCOA_03014	0.0	uvrA2	-	-	L	-	-	-	ABC transporter
HDLMBCOA_03015	7.12e-62	-	-	-	-	-	-	-	-
HDLMBCOA_03016	8.82e-119	-	-	-	-	-	-	-	-
HDLMBCOA_03017	2.2e-111	ohrR	-	-	K	ko:K18906	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
HDLMBCOA_03018	1.23e-145	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HDLMBCOA_03019	4.56e-78	-	-	-	-	-	-	-	-
HDLMBCOA_03020	5.37e-74	-	-	-	-	-	-	-	-
HDLMBCOA_03021	9.01e-179	agrA	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HDLMBCOA_03022	8.83e-285	pltK	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HDLMBCOA_03023	7.83e-140	-	-	-	-	-	-	-	-
HDLMBCOA_03024	1.14e-190	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HDLMBCOA_03025	2.09e-85	-	-	-	-	-	-	-	-
HDLMBCOA_03026	9.2e-317	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDLMBCOA_03027	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HDLMBCOA_03028	1.9e-148	-	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
HDLMBCOA_03029	9.82e-111	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HDLMBCOA_03031	2.38e-229	-	-	-	S	-	-	-	MucBP domain
HDLMBCOA_03032	1.24e-307	-	-	-	S	-	-	-	MucBP domain
HDLMBCOA_03033	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HDLMBCOA_03034	1.06e-205	-	-	-	K	-	-	-	LysR substrate binding domain
HDLMBCOA_03035	1.07e-200	-	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NADH pyrophosphatase zinc ribbon domain
HDLMBCOA_03036	2.8e-135	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HDLMBCOA_03037	1.72e-215	-	3.1.4.17, 3.1.4.53	-	S	ko:K01120,ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
HDLMBCOA_03038	6.46e-49	-	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
HDLMBCOA_03039	1.28e-77	-	-	-	S	-	-	-	Enterocin A Immunity
HDLMBCOA_03040	1.55e-114	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HDLMBCOA_03041	1.78e-139	-	-	-	-	-	-	-	-
HDLMBCOA_03042	3.43e-303	-	-	-	S	-	-	-	module of peptide synthetase
HDLMBCOA_03043	8.66e-130	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HDLMBCOA_03045	8.42e-163	nth2	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
HDLMBCOA_03046	0.0	pts28ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HDLMBCOA_03047	7.54e-200	-	-	-	GM	-	-	-	NmrA-like family
HDLMBCOA_03048	4.08e-101	-	-	-	K	-	-	-	MerR family regulatory protein
HDLMBCOA_03049	2.09e-16	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HDLMBCOA_03050	0.0	-	-	-	-	-	-	-	-
HDLMBCOA_03051	1.39e-211	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
HDLMBCOA_03052	1.58e-66	-	-	-	-	-	-	-	-
HDLMBCOA_03053	6.47e-124	-	-	-	K	ko:K22041	-	ko00000,ko03000	transcriptional regulator
HDLMBCOA_03054	4.88e-117	ymdB	-	-	S	-	-	-	Macro domain protein
HDLMBCOA_03055	2.69e-190	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HDLMBCOA_03056	1.5e-56	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HDLMBCOA_03057	1.7e-101	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HDLMBCOA_03058	2.57e-171	-	-	-	S	-	-	-	Putative threonine/serine exporter
HDLMBCOA_03059	1.36e-209	yvgN	-	-	C	-	-	-	Aldo keto reductase
HDLMBCOA_03060	2.3e-204	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HDLMBCOA_03061	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HDLMBCOA_03063	2.41e-97	-	-	-	M	-	-	-	PFAM NLP P60 protein
HDLMBCOA_03064	0.0	gadB	4.1.1.15, 4.1.2.27	-	E	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Belongs to the group II decarboxylase family
HDLMBCOA_03065	4.45e-38	-	-	-	-	-	-	-	-
HDLMBCOA_03066	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
HDLMBCOA_03067	3.81e-150	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDLMBCOA_03068	5.33e-114	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HDLMBCOA_03069	1.63e-176	yesN	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
HDLMBCOA_03070	5.48e-171	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HDLMBCOA_03071	6.48e-244	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HDLMBCOA_03072	2.06e-299	-	-	-	-	-	-	-	-
HDLMBCOA_03073	2e-62	-	-	-	K	-	-	-	Helix-turn-helix domain
HDLMBCOA_03074	1.23e-254	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
HDLMBCOA_03075	5.31e-66	-	-	-	K	-	-	-	Helix-turn-helix domain
HDLMBCOA_03076	2.38e-80	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HDLMBCOA_03077	5.36e-76	-	-	-	-	-	-	-	-
HDLMBCOA_03078	2.33e-56	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HDLMBCOA_03079	1.31e-139	yoaZ	-	-	S	-	-	-	intracellular protease amidase
HDLMBCOA_03080	8.53e-59	-	-	-	S	-	-	-	Protein of unknown function (DUF3781)
HDLMBCOA_03081	2.23e-279	-	-	-	S	-	-	-	Membrane
HDLMBCOA_03082	5.98e-85	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HDLMBCOA_03083	4.83e-31	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HDLMBCOA_03084	5.61e-54	pcaC	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
HDLMBCOA_03085	5.15e-16	-	-	-	-	-	-	-	-
HDLMBCOA_03088	2.12e-101	-	-	-	-	-	-	-	-
HDLMBCOA_03089	4.47e-70	-	-	-	-	-	-	-	-
HDLMBCOA_03092	2.31e-09	-	-	-	K	-	-	-	Transcriptional regulator, XRE family
HDLMBCOA_03093	1.19e-24	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HDLMBCOA_03097	2.06e-50	-	-	-	K	-	-	-	Helix-turn-helix
HDLMBCOA_03098	2.67e-80	-	-	-	K	-	-	-	Helix-turn-helix domain
HDLMBCOA_03099	9.47e-94	-	-	-	E	-	-	-	IrrE N-terminal-like domain
HDLMBCOA_03100	7.9e-74	-	-	-	-	-	-	-	-
HDLMBCOA_03103	3e-66	-	-	-	-	-	-	-	-
HDLMBCOA_03107	2.61e-16	-	-	-	-	-	-	-	-
HDLMBCOA_03108	5.42e-278	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HDLMBCOA_03110	8.08e-40	-	-	-	-	-	-	-	-
HDLMBCOA_03112	1.28e-51	-	-	-	-	-	-	-	-
HDLMBCOA_03113	1.09e-56	-	-	-	-	-	-	-	-
HDLMBCOA_03114	5.21e-137	-	-	-	S	ko:K09962	-	ko00000	Nucleotidyltransferase
HDLMBCOA_03115	1.23e-106	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HDLMBCOA_03116	1.03e-284	ribA	3.5.4.25, 4.1.99.12	-	H	ko:K02858,ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HDLMBCOA_03117	8.71e-111	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
HDLMBCOA_03118	4.26e-218	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HDLMBCOA_03119	0.0	-	-	-	S	-	-	-	membrane
HDLMBCOA_03120	4.29e-26	-	-	-	S	-	-	-	NUDIX domain
HDLMBCOA_03121	7.41e-298	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HDLMBCOA_03122	2.7e-90	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HDLMBCOA_03123	3.85e-234	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
HDLMBCOA_03124	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HDLMBCOA_03125	1.56e-46	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
HDLMBCOA_03126	5.8e-291	araT	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HDLMBCOA_03127	3.79e-291	dacA2	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HDLMBCOA_03128	2.16e-241	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HDLMBCOA_03129	2.04e-254	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HDLMBCOA_03130	1.41e-285	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HDLMBCOA_03131	1.12e-123	-	-	-	D	-	-	-	nuclear chromosome segregation
HDLMBCOA_03132	1.71e-52	-	-	-	-	-	-	-	-
HDLMBCOA_03133	1.7e-200	-	-	-	L	-	-	-	Initiator Replication protein
HDLMBCOA_03134	5.51e-38	-	-	-	-	-	-	-	-
HDLMBCOA_03135	7.3e-137	-	-	-	L	-	-	-	Integrase
HDLMBCOA_03136	1.83e-58	-	-	-	T	ko:K07172	-	ko00000,ko02048	Antidote-toxin recognition MazE, bacterial antitoxin
HDLMBCOA_03137	3.2e-76	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
HDLMBCOA_03140	1.12e-06	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HDLMBCOA_03142	4.77e-69	-	-	-	D	-	-	-	nuclear chromosome segregation
HDLMBCOA_03143	0.0	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HDLMBCOA_03144	0.0	lepA2	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HDLMBCOA_03145	6.88e-152	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDLMBCOA_03146	2.05e-260	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
HDLMBCOA_03147	1.1e-115	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HDLMBCOA_03148	9.19e-229	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HDLMBCOA_03149	2.77e-168	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HDLMBCOA_03150	5.39e-196	-	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
HDLMBCOA_03151	1.58e-59	-	-	-	L	-	-	-	Transposase DDE domain
HDLMBCOA_03152	4.45e-38	-	-	-	-	-	-	-	-
HDLMBCOA_03153	4.64e-159	-	-	-	S	-	-	-	Fic/DOC family
HDLMBCOA_03154	2.35e-52	-	-	-	-	-	-	-	-
HDLMBCOA_03155	1.69e-37	-	-	-	-	-	-	-	-
HDLMBCOA_03156	0.0	traA	-	-	L	-	-	-	MobA MobL family protein
HDLMBCOA_03157	0.0	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HDLMBCOA_03158	1.89e-255	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HDLMBCOA_03160	2.46e-25	-	-	-	D	-	-	-	protein tyrosine kinase activity
HDLMBCOA_03162	1.74e-110	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HDLMBCOA_03163	9.98e-100	cps3A	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
HDLMBCOA_03164	4.84e-23	yibD	-	GT2	M	ko:K19354	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferases involved in cell wall biogenesis
HDLMBCOA_03165	1.54e-94	wefC	-	-	M	-	-	-	Stealth protein CR2, conserved region 2
HDLMBCOA_03166	6.41e-110	-	-	-	P	ko:K19419	-	ko00000,ko02000	EpsG family
HDLMBCOA_03167	2.79e-165	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
HDLMBCOA_03168	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HDLMBCOA_03169	0.0	pts4ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HDLMBCOA_03170	0.0	pts5ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HDLMBCOA_03171	2.6e-185	-	-	-	-	-	-	-	-
HDLMBCOA_03172	2.66e-126	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HDLMBCOA_03173	3.78e-60	-	-	-	-	-	-	-	-
HDLMBCOA_03174	9.53e-317	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
HDLMBCOA_03175	4.29e-173	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HDLMBCOA_03176	3.25e-232	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HDLMBCOA_03177	2.13e-152	-	-	-	K	-	-	-	Transcriptional regulator
HDLMBCOA_03178	5.71e-159	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HDLMBCOA_03179	1.36e-132	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HDLMBCOA_03180	7.54e-115	yrxA	-	-	S	ko:K07105	-	ko00000	3H domain
HDLMBCOA_03181	1.73e-236	-	-	-	EGP	-	-	-	Transmembrane secretion effector
HDLMBCOA_03182	1.05e-22	-	-	-	EGP	-	-	-	Major Facilitator
HDLMBCOA_03183	9.94e-123	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
HDLMBCOA_03184	9.51e-83	is18	-	-	L	-	-	-	COG2801 Transposase and inactivated derivatives
HDLMBCOA_03185	3.77e-100	is18	-	-	L	-	-	-	Integrase core domain
HDLMBCOA_03186	5.82e-43	-	-	-	L	ko:K07483	-	ko00000	Transposase and inactivated derivatives
HDLMBCOA_03188	3.13e-08	-	-	-	K	-	-	-	transcriptional regulator
HDLMBCOA_03189	1.77e-97	-	-	-	S	-	-	-	Protein of unknown function with HXXEE motif
HDLMBCOA_03190	2.32e-53	-	-	-	K	-	-	-	Putative DNA-binding domain
HDLMBCOA_03191	3.97e-155	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
HDLMBCOA_03192	1.36e-55	yejC	-	-	S	-	-	-	Protein of unknown function (DUF1003)
HDLMBCOA_03193	1.05e-176	XK27_00890	-	-	S	ko:K08974	-	ko00000	Domain of unknown function (DUF368)
HDLMBCOA_03194	7.45e-313	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HDLMBCOA_03195	2.79e-181	-	-	-	-	-	-	-	-
HDLMBCOA_03196	7.79e-78	-	-	-	-	-	-	-	-
HDLMBCOA_03197	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HDLMBCOA_03198	8.23e-291	-	-	-	-	-	-	-	-
HDLMBCOA_03199	5.09e-282	mdtG	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HDLMBCOA_03200	5.99e-231	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HDLMBCOA_03201	6.1e-101	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HDLMBCOA_03202	1.14e-110	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
HDLMBCOA_03203	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
HDLMBCOA_03204	2.09e-35	-	-	-	-	-	-	-	-
HDLMBCOA_03205	1.94e-91	tagD	2.7.7.15, 2.7.7.39	-	IM	ko:K00968,ko:K00980	ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231	ko00000,ko00001,ko00002,ko01000	Glycerol-3-phosphate cytidylyltransferase
HDLMBCOA_03206	4.5e-224	tagB	2.7.8.12, 2.7.8.45	-	M	ko:K09809,ko:K21591	-	ko00000,ko01000	glycerophosphotransferase
HDLMBCOA_03207	0.0	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HDLMBCOA_03208	6.18e-71	-	-	-	-	-	-	-	-
HDLMBCOA_03209	5.77e-81	-	-	-	-	-	-	-	-
HDLMBCOA_03211	9.39e-84	-	-	-	-	-	-	-	-
HDLMBCOA_03213	1.12e-134	-	-	-	K	-	-	-	transcriptional regulator
HDLMBCOA_03214	4.84e-230	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
HDLMBCOA_03215	3.42e-174	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HDLMBCOA_03216	1.5e-165	-	-	-	S	-	-	-	Gram-negative-bacterium-type cell wall biogenesis
HDLMBCOA_03217	1.14e-231	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HDLMBCOA_03218	6.39e-169	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HDLMBCOA_03219	3.28e-165	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HDLMBCOA_03220	1.9e-230	-	-	-	S	ko:K06889	-	ko00000	Prolyl oligopeptidase family
HDLMBCOA_03221	2.26e-209	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HDLMBCOA_03222	1.97e-49	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
HDLMBCOA_03223	1.19e-201	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HDLMBCOA_03224	1.6e-127	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HDLMBCOA_03225	1.63e-187	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
HDLMBCOA_03226	1.9e-260	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HDLMBCOA_03227	1.33e-77	-	-	-	-	-	-	-	-
HDLMBCOA_03228	5.37e-182	-	-	-	-	-	-	-	-
HDLMBCOA_03229	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HDLMBCOA_03230	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HDLMBCOA_03231	5.63e-89	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HDLMBCOA_03232	1.22e-220	-	-	-	L	-	-	-	Initiator Replication protein
HDLMBCOA_03233	9.47e-86	-	-	-	S	-	-	-	Protein of unknown function, DUF536
HDLMBCOA_03234	1.83e-70	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
HDLMBCOA_03236	1.5e-76	-	-	-	S	-	-	-	Bacterial toxin of type II toxin-antitoxin system, YafQ
HDLMBCOA_03237	1.11e-59	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
HDLMBCOA_03238	2.18e-138	-	-	-	L	-	-	-	Integrase
HDLMBCOA_03239	3.66e-82	-	-	-	-	-	-	-	-
HDLMBCOA_03240	1.76e-39	-	-	-	-	-	-	-	-
HDLMBCOA_03242	6.13e-127	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
HDLMBCOA_03244	1.27e-221	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HDLMBCOA_03245	1.2e-50	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HDLMBCOA_03246	1.75e-42	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HDLMBCOA_03247	2.48e-52	-	-	-	L	ko:K07483	-	ko00000	Transposase and inactivated derivatives
HDLMBCOA_03248	5.94e-201	is18	-	-	L	-	-	-	Integrase core domain
HDLMBCOA_03249	4.51e-46	-	-	-	S	-	-	-	Protein of unknown function DUF262
HDLMBCOA_03250	1.23e-60	-	3.1.21.4	-	K	ko:K01155	-	ko00000,ko01000,ko02048	sequence-specific DNA binding
HDLMBCOA_03251	1.82e-144	-	2.1.1.113	-	L	ko:K00590	-	ko00000,ko01000,ko02048	DNA methylase
HDLMBCOA_03253	7.93e-47	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
HDLMBCOA_03257	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
HDLMBCOA_03258	1.35e-38	-	-	-	-	-	-	-	-
HDLMBCOA_03259	1.35e-56	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
HDLMBCOA_03260	2.35e-178	repA	-	-	S	-	-	-	Replication initiator protein A
HDLMBCOA_03262	8.87e-173	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
HDLMBCOA_03263	1.08e-136	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDLMBCOA_03264	2.22e-59	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HDLMBCOA_03266	2.34e-90	thiF	2.7.7.73	-	H	ko:K03148	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	ThiF family
HDLMBCOA_03267	4.36e-148	-	-	-	EGP	-	-	-	Transmembrane secretion effector
HDLMBCOA_03268	0.0	traA	-	-	L	-	-	-	MobA MobL family protein
HDLMBCOA_03270	9.34e-94	-	-	-	-	-	-	-	-
HDLMBCOA_03271	6.32e-66	-	-	-	S	-	-	-	Cag pathogenicity island, type IV secretory system
HDLMBCOA_03272	3.25e-72	-	-	-	-	-	-	-	-
HDLMBCOA_03273	9.01e-104	-	-	-	-	-	-	-	-
HDLMBCOA_03275	3.37e-63	-	-	-	S	-	-	-	Family of unknown function (DUF5388)
HDLMBCOA_03276	5.66e-189	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
HDLMBCOA_03277	5.37e-112	-	-	-	L	ko:K07483,ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Helix-turn-helix domain
HDLMBCOA_03278	4.05e-211	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HDLMBCOA_03279	1.91e-44	-	-	-	C	-	-	-	Flavodoxin
HDLMBCOA_03280	7.53e-102	-	-	-	GM	-	-	-	NmrA-like family
HDLMBCOA_03281	2.62e-173	-	-	-	C	-	-	-	Aldo/keto reductase family
HDLMBCOA_03282	4.69e-87	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
HDLMBCOA_03283	2.15e-86	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
HDLMBCOA_03284	1.94e-15	-	-	-	C	-	-	-	Flavodoxin
HDLMBCOA_03285	2.03e-31	-	-	-	S	-	-	-	Family of unknown function (DUF5388)
HDLMBCOA_03286	1.18e-184	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
HDLMBCOA_03287	5.3e-49	-	-	-	L	-	-	-	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HDLMBCOA_03288	2.17e-26	-	-	-	-	-	-	-	-
HDLMBCOA_03289	3.49e-205	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HDLMBCOA_03290	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HDLMBCOA_03291	1.13e-228	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein-like domain
HDLMBCOA_03292	9.54e-158	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDLMBCOA_03293	1.37e-05	-	-	-	-	-	-	-	-
HDLMBCOA_03294	3.31e-37	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HDLMBCOA_03295	8.89e-20	-	-	-	S	-	-	-	YjzC-like protein
HDLMBCOA_03296	5.05e-85	-	-	-	L	-	-	-	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HDLMBCOA_03297	3.7e-80	-	-	-	-	-	-	-	-
HDLMBCOA_03298	5.17e-82	-	-	-	K	ko:K07741	-	ko00000	AntA/AntB antirepressor
HDLMBCOA_03299	2.12e-63	-	-	-	-	-	-	-	-
HDLMBCOA_03300	1.79e-198	-	-	-	L	-	-	-	DnaD domain protein
HDLMBCOA_03301	9.69e-301	aspD	4.1.1.12	-	E	ko:K09758	ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230	ko00000,ko00001,ko01000	Aminotransferase class I and II
HDLMBCOA_03302	2.17e-247	-	-	-	U	ko:K07085	-	ko00000	Predicted Permease Membrane Region
HDLMBCOA_03303	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HDLMBCOA_03304	5.26e-245	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HDLMBCOA_03305	1.06e-124	gbuC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
HDLMBCOA_03306	4.63e-143	gbuB	-	-	E	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
HDLMBCOA_03307	2.97e-234	gbuA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
HDLMBCOA_03310	1.57e-213	-	-	-	L	-	-	-	Replication protein
HDLMBCOA_03311	2.47e-174	mob	-	-	D	-	-	-	Plasmid recombination enzyme
HDLMBCOA_03312	0.0	ybeC	-	-	E	-	-	-	amino acid
HDLMBCOA_03313	1.66e-245	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HDLMBCOA_03314	0.0	dld	1.1.5.12	-	C	ko:K03777	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	D-lactate dehydrogenase, membrane binding
HDLMBCOA_03315	5.79e-37	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HDLMBCOA_03316	1.13e-176	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HDLMBCOA_03317	3.31e-109	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HDLMBCOA_03318	1.02e-69	-	-	-	S	-	-	-	SMI1-KNR4 cell-wall
HDLMBCOA_03320	3.06e-110	cps3A	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
HDLMBCOA_03321	1.39e-97	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HDLMBCOA_03322	1.92e-222	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HDLMBCOA_03323	0.0	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
HDLMBCOA_03324	4.13e-231	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HDLMBCOA_03325	1.38e-19	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HDLMBCOA_03327	1.5e-194	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HDLMBCOA_03328	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
HDLMBCOA_03330	4.42e-81	traA	-	-	L	-	-	-	MobA/MobL family
HDLMBCOA_03331	5.1e-274	-	-	-	S	-	-	-	Protein of unknown function DUF262
HDLMBCOA_03332	8.12e-82	-	-	-	L	-	-	-	Transposase DDE domain
HDLMBCOA_03333	1.15e-261	butB	1.1.1.14, 1.1.1.264, 1.1.1.303, 1.1.1.4	-	C	ko:K00004,ko:K00008,ko:K00098	ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
HDLMBCOA_03334	1.15e-77	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HDLMBCOA_03335	2.38e-113	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HDLMBCOA_03337	4.61e-222	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HDLMBCOA_03338	2.44e-63	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
HDLMBCOA_03339	2.34e-35	-	-	-	-	-	-	-	-
HDLMBCOA_03340	5.86e-148	-	-	-	S	-	-	-	Plasmid replication protein
HDLMBCOA_03342	2.83e-58	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
HDLMBCOA_03343	6.71e-107	-	-	-	-	-	-	-	-
HDLMBCOA_03344	6.39e-104	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HDLMBCOA_03345	1.51e-200	-	-	-	K	-	-	-	LysR substrate binding domain
HDLMBCOA_03346	6.09e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
HDLMBCOA_03347	5.01e-229	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HDLMBCOA_03348	4.76e-200	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HDLMBCOA_03349	2.07e-170	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HDLMBCOA_03350	9.54e-65	-	-	-	K	-	-	-	sequence-specific DNA binding
HDLMBCOA_03353	4.99e-130	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HDLMBCOA_03355	3.33e-121	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
HDLMBCOA_03356	1.61e-23	-	-	-	EGP	-	-	-	Major Facilitator
HDLMBCOA_03357	2.21e-78	-	-	-	-	-	-	-	-
HDLMBCOA_03358	2.13e-141	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HDLMBCOA_03359	2.99e-82	-	-	-	S	ko:K09705	-	ko00000	Cupin superfamily (DUF985)
HDLMBCOA_03360	2.79e-06	-	-	-	Q	-	-	-	Domain of unknown function (DUF4062)
HDLMBCOA_03361	1.86e-72	-	-	-	L	-	-	-	Helix-turn-helix domain
HDLMBCOA_03363	6.21e-220	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
HDLMBCOA_03364	4.16e-234	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
HDLMBCOA_03365	2.44e-148	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HDLMBCOA_03366	1.5e-156	gpm5	-	-	G	-	-	-	Phosphoglycerate mutase family
HDLMBCOA_03367	5.97e-241	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
HDLMBCOA_03368	1.48e-81	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HDLMBCOA_03369	1.96e-137	-	-	-	-	-	-	-	-
HDLMBCOA_03372	7.72e-48	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HDLMBCOA_03373	8.19e-49	-	-	-	L	-	-	-	Transposase DDE domain
HDLMBCOA_03374	2.14e-163	tnp1216	-	-	L	ko:K07498	-	ko00000	DDE domain
HDLMBCOA_03375	2.09e-40	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HDLMBCOA_03376	4.3e-46	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HDLMBCOA_03379	2.5e-90	-	-	-	L	-	-	-	manually curated
HDLMBCOA_03380	4.67e-39	-	-	-	K	-	-	-	Sigma-54 interaction domain
HDLMBCOA_03381	3.33e-89	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HDLMBCOA_03382	5.27e-26	-	-	-	-	-	-	-	-
HDLMBCOA_03384	2.48e-29	tnpR	-	-	L	-	-	-	Resolvase, N terminal domain