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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
PKEHELCK_00001	2.73e-205	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
PKEHELCK_00002	5.58e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
PKEHELCK_00003	5.28e-100	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
PKEHELCK_00004	6.05e-108	tspO	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	TspO/MBR family
PKEHELCK_00005	2.05e-55	-	-	-	-	-	-	-	-
PKEHELCK_00006	5.93e-60	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
PKEHELCK_00007	9.96e-147	-	1.14.99.53	AA10	S	ko:K21713	-	ko00000,ko01000	Lytic polysaccharide mono-oxygenase, cellulose-degrading
PKEHELCK_00008	1.05e-41	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
PKEHELCK_00009	6.57e-274	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
PKEHELCK_00010	2.02e-39	-	-	-	-	-	-	-	-
PKEHELCK_00011	1.48e-71	-	-	-	-	-	-	-	-
PKEHELCK_00012	1.14e-193	-	-	-	O	-	-	-	Band 7 protein
PKEHELCK_00013	0.0	-	-	-	EGP	-	-	-	Major Facilitator
PKEHELCK_00014	6.05e-121	-	-	-	K	-	-	-	transcriptional regulator
PKEHELCK_00015	4.4e-246	rsgA_2	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PKEHELCK_00016	2.01e-113	ykhA	-	-	I	-	-	-	Thioesterase superfamily
PKEHELCK_00017	7.52e-207	-	-	-	K	-	-	-	LysR substrate binding domain
PKEHELCK_00018	1.48e-161	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
PKEHELCK_00019	5.01e-129	-	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
PKEHELCK_00020	2.29e-175	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
PKEHELCK_00021	4.82e-179	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
PKEHELCK_00022	6.43e-203	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PKEHELCK_00023	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
PKEHELCK_00024	1.71e-91	fabZ2	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
PKEHELCK_00025	2.14e-95	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PKEHELCK_00026	7.64e-290	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PKEHELCK_00027	1.26e-162	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
PKEHELCK_00028	3.47e-215	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
PKEHELCK_00029	6.16e-48	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PKEHELCK_00030	1.62e-229	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PKEHELCK_00031	8.55e-99	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PKEHELCK_00032	1.62e-229	yneE	-	-	K	-	-	-	Transcriptional regulator
PKEHELCK_00033	5.62e-185	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
PKEHELCK_00035	1.49e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
PKEHELCK_00036	2.69e-252	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
PKEHELCK_00037	6.54e-272	hipO1	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	Peptidase family M20/M25/M40
PKEHELCK_00038	4.84e-278	-	-	-	E	-	-	-	glutamate:sodium symporter activity
PKEHELCK_00039	1.95e-88	ybbJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
PKEHELCK_00040	2.04e-226	-	1.6.5.5	-	C	ko:K00344	-	ko00000,ko01000	Zinc-binding dehydrogenase
PKEHELCK_00041	5.89e-126	entB	-	-	Q	-	-	-	Isochorismatase family
PKEHELCK_00042	4.82e-183	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
PKEHELCK_00043	6.25e-288	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
PKEHELCK_00044	4.5e-142	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
PKEHELCK_00045	1.2e-165	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
PKEHELCK_00046	9.99e-225	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PKEHELCK_00047	5.46e-133	trpG	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Peptidase C26
PKEHELCK_00048	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Anthranilate synthase component I, N terminal region
PKEHELCK_00050	0.0	XK27_00765	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
PKEHELCK_00051	2.05e-179	ecsA_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
PKEHELCK_00052	9.06e-112	-	-	-	-	-	-	-	-
PKEHELCK_00053	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
PKEHELCK_00054	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
PKEHELCK_00055	3.2e-70	-	-	-	-	-	-	-	-
PKEHELCK_00056	3.15e-78	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PKEHELCK_00057	1.57e-179	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
PKEHELCK_00058	6.42e-123	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PKEHELCK_00059	9.99e-53	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
PKEHELCK_00060	1.6e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
PKEHELCK_00061	7.69e-300	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PKEHELCK_00062	1.46e-77	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
PKEHELCK_00063	2.85e-293	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PKEHELCK_00064	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
PKEHELCK_00065	4.49e-167	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PKEHELCK_00066	3.33e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PKEHELCK_00067	2.17e-244	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
PKEHELCK_00068	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PKEHELCK_00069	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
PKEHELCK_00070	7.09e-76	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
PKEHELCK_00071	1.61e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
PKEHELCK_00072	1.84e-160	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
PKEHELCK_00073	3.16e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
PKEHELCK_00074	1.21e-209	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PKEHELCK_00075	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
PKEHELCK_00076	1.62e-173	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
PKEHELCK_00077	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PKEHELCK_00078	4.09e-222	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PKEHELCK_00079	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PKEHELCK_00080	5.04e-278	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PKEHELCK_00081	3.93e-41	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
PKEHELCK_00082	2.83e-144	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
PKEHELCK_00083	8.28e-73	-	-	-	-	-	-	-	-
PKEHELCK_00084	1.36e-136	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PKEHELCK_00085	3.8e-224	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
PKEHELCK_00086	7.11e-135	opuCB	-	-	E	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PKEHELCK_00087	7.48e-283	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
PKEHELCK_00088	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
PKEHELCK_00089	5.28e-100	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
PKEHELCK_00090	4.49e-192	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
PKEHELCK_00091	1.16e-200	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
PKEHELCK_00092	7.55e-44	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PKEHELCK_00093	1.14e-312	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PKEHELCK_00094	4.82e-194	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PKEHELCK_00095	2.82e-91	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PKEHELCK_00096	1.7e-96	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
PKEHELCK_00097	1.43e-129	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PKEHELCK_00098	3.49e-248	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
PKEHELCK_00099	2.33e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
PKEHELCK_00100	7.97e-71	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
PKEHELCK_00101	1.55e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
PKEHELCK_00102	8.15e-125	-	-	-	K	-	-	-	Transcriptional regulator
PKEHELCK_00103	9.81e-27	-	-	-	-	-	-	-	-
PKEHELCK_00106	2.97e-41	-	-	-	-	-	-	-	-
PKEHELCK_00107	3.11e-73	-	-	-	-	-	-	-	-
PKEHELCK_00108	2.92e-126	-	-	-	S	-	-	-	Protein conserved in bacteria
PKEHELCK_00109	1.9e-232	-	-	-	-	-	-	-	-
PKEHELCK_00110	4.11e-206	-	-	-	-	-	-	-	-
PKEHELCK_00111	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
PKEHELCK_00112	7.79e-85	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
PKEHELCK_00113	3.8e-224	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PKEHELCK_00114	7.77e-179	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
PKEHELCK_00115	1.44e-31	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
PKEHELCK_00116	1.15e-89	yqhL	-	-	P	-	-	-	Rhodanese-like protein
PKEHELCK_00117	1.62e-141	pepE	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
PKEHELCK_00118	2.6e-231	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
PKEHELCK_00119	6.33e-46	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
PKEHELCK_00120	3.52e-153	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
PKEHELCK_00121	9.29e-132	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PKEHELCK_00122	5.33e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
PKEHELCK_00123	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
PKEHELCK_00124	0.0	-	-	-	S	-	-	-	membrane
PKEHELCK_00125	2.5e-71	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
PKEHELCK_00126	2.33e-98	-	-	-	K	-	-	-	LytTr DNA-binding domain
PKEHELCK_00127	3.78e-143	-	-	-	S	-	-	-	membrane
PKEHELCK_00128	1.09e-105	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PKEHELCK_00129	7.5e-146	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
PKEHELCK_00130	6.11e-249	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PKEHELCK_00131	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PKEHELCK_00132	6.88e-257	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PKEHELCK_00133	1.09e-83	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
PKEHELCK_00134	1.72e-120	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
PKEHELCK_00135	4.46e-179	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PKEHELCK_00136	1.37e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
PKEHELCK_00137	1.99e-208	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PKEHELCK_00138	1.77e-122	-	-	-	S	-	-	-	SdpI/YhfL protein family
PKEHELCK_00139	7.88e-288	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
PKEHELCK_00140	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
PKEHELCK_00141	1.93e-218	ubiA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
PKEHELCK_00142	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PKEHELCK_00143	1.38e-155	csrR	-	-	K	-	-	-	response regulator
PKEHELCK_00144	1.27e-310	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
PKEHELCK_00145	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PKEHELCK_00146	9.32e-225	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PKEHELCK_00147	3.06e-124	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
PKEHELCK_00148	3.66e-127	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
PKEHELCK_00149	3.04e-280	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
PKEHELCK_00150	3.3e-180	yqeM	-	-	Q	-	-	-	Methyltransferase
PKEHELCK_00151	1.06e-76	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PKEHELCK_00152	1.71e-149	yqeK	-	-	H	-	-	-	Hydrolase, HD family
PKEHELCK_00153	4.19e-153	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PKEHELCK_00154	2.19e-67	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
PKEHELCK_00155	2.21e-275	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
PKEHELCK_00156	5.7e-127	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
PKEHELCK_00157	8.99e-114	-	-	-	-	-	-	-	-
PKEHELCK_00158	1.9e-315	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
PKEHELCK_00159	2.39e-175	racD	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
PKEHELCK_00160	1.64e-83	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
PKEHELCK_00161	9.67e-250	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
PKEHELCK_00162	1.43e-288	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
PKEHELCK_00163	4.59e-73	-	-	-	-	-	-	-	-
PKEHELCK_00164	6.88e-73	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PKEHELCK_00165	6.92e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
PKEHELCK_00166	2.37e-109	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PKEHELCK_00167	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PKEHELCK_00168	3.5e-220	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
PKEHELCK_00169	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
PKEHELCK_00170	1.58e-117	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PKEHELCK_00171	1.92e-133	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PKEHELCK_00172	3.19e-202	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
PKEHELCK_00173	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PKEHELCK_00174	8.51e-155	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
PKEHELCK_00175	1.04e-141	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
PKEHELCK_00176	4.07e-60	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
PKEHELCK_00177	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
PKEHELCK_00178	2.71e-108	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
PKEHELCK_00179	3.17e-299	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PKEHELCK_00180	1.49e-310	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
PKEHELCK_00181	1.1e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
PKEHELCK_00182	2.87e-47	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
PKEHELCK_00183	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
PKEHELCK_00184	3.04e-29	-	-	-	S	-	-	-	Virus attachment protein p12 family
PKEHELCK_00185	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
PKEHELCK_00186	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
PKEHELCK_00187	1.29e-148	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PKEHELCK_00188	4.89e-70	ytzB	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
PKEHELCK_00189	2.8e-155	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PKEHELCK_00190	7.24e-197	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
PKEHELCK_00191	8.17e-285	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
PKEHELCK_00192	1.1e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PKEHELCK_00193	3.6e-106	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
PKEHELCK_00194	6.76e-73	-	-	-	-	-	-	-	-
PKEHELCK_00195	1.09e-196	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
PKEHELCK_00196	2.93e-152	draG	-	-	O	-	-	-	ADP-ribosylglycohydrolase
PKEHELCK_00197	5.76e-135	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
PKEHELCK_00198	2.82e-138	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
PKEHELCK_00199	5.57e-247	-	-	-	S	-	-	-	Fn3-like domain
PKEHELCK_00200	1.65e-80	-	-	-	-	-	-	-	-
PKEHELCK_00201	0.0	-	-	-	-	-	-	-	-
PKEHELCK_00202	5.19e-309	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
PKEHELCK_00203	4.89e-146	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PKEHELCK_00204	3.3e-151	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
PKEHELCK_00205	1.96e-137	-	-	-	-	-	-	-	-
PKEHELCK_00206	5.21e-137	-	-	-	S	ko:K09962	-	ko00000	Nucleotidyltransferase
PKEHELCK_00207	1.23e-106	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
PKEHELCK_00208	1.03e-284	ribA	3.5.4.25, 4.1.99.12	-	H	ko:K02858,ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
PKEHELCK_00209	8.71e-111	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
PKEHELCK_00210	4.26e-218	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PKEHELCK_00211	0.0	-	-	-	S	-	-	-	membrane
PKEHELCK_00212	4.29e-26	-	-	-	S	-	-	-	NUDIX domain
PKEHELCK_00213	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PKEHELCK_00214	1.15e-235	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
PKEHELCK_00215	1.17e-100	-	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside 2-deoxyribosyltransferase
PKEHELCK_00216	4.43e-129	-	-	-	-	-	-	-	-
PKEHELCK_00217	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
PKEHELCK_00218	9.9e-144	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
PKEHELCK_00219	6.59e-227	-	-	-	K	-	-	-	LysR substrate binding domain
PKEHELCK_00220	2.41e-233	-	-	-	M	-	-	-	Peptidase family S41
PKEHELCK_00221	1.05e-272	-	-	-	-	-	-	-	-
PKEHELCK_00222	1.03e-240	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
PKEHELCK_00223	0.0	yhaN	-	-	L	-	-	-	AAA domain
PKEHELCK_00224	4.47e-296	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
PKEHELCK_00225	9.94e-71	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
PKEHELCK_00226	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
PKEHELCK_00227	2.43e-18	-	-	-	-	-	-	-	-
PKEHELCK_00228	2.07e-102	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
PKEHELCK_00229	3.23e-270	arcT	-	-	E	-	-	-	Aminotransferase
PKEHELCK_00230	8.08e-133	argO	-	-	S	ko:K06895	-	ko00000,ko02000	LysE type translocator
PKEHELCK_00231	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	Alanine-glyoxylate amino-transferase
PKEHELCK_00232	1.65e-46	dltC2	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PKEHELCK_00233	1.72e-148	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
PKEHELCK_00234	7.06e-271	-	-	-	EGP	ko:K08218	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Major facilitator Superfamily
PKEHELCK_00235	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
PKEHELCK_00236	1.02e-285	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PKEHELCK_00237	4.9e-64	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
PKEHELCK_00238	2.37e-68	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
PKEHELCK_00239	1.34e-104	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
PKEHELCK_00240	0.0	celR	-	-	K	-	-	-	PRD domain
PKEHELCK_00241	6.25e-138	-	-	-	-	-	-	-	-
PKEHELCK_00242	5.52e-94	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
PKEHELCK_00243	8.77e-265	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
PKEHELCK_00244	7.7e-68	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
PKEHELCK_00245	4.64e-106	-	-	-	-	-	-	-	-
PKEHELCK_00246	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
PKEHELCK_00247	3.34e-101	yybD	-	-	S	ko:K02348	-	ko00000	Acetyltransferase (GNAT) domain
PKEHELCK_00250	1.79e-42	-	-	-	-	-	-	-	-
PKEHELCK_00251	2.69e-316	dinF	-	-	V	-	-	-	MatE
PKEHELCK_00252	0.0	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
PKEHELCK_00253	2.27e-166	astA	2.8.2.22	-	M	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
PKEHELCK_00254	0.0	-	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 85
PKEHELCK_00255	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
PKEHELCK_00256	2.44e-267	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PKEHELCK_00257	0.0	malS	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Glycogen debranching enzyme, glucanotransferase domain
PKEHELCK_00258	2.91e-190	malA	-	-	S	-	-	-	maltodextrose utilization protein MalA
PKEHELCK_00259	2.83e-206	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PKEHELCK_00260	3.74e-302	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PKEHELCK_00261	9.45e-299	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
PKEHELCK_00262	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
PKEHELCK_00263	1.83e-231	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
PKEHELCK_00264	2.65e-245	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
PKEHELCK_00265	4e-172	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
PKEHELCK_00266	6.76e-75	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
PKEHELCK_00267	2.75e-131	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
PKEHELCK_00268	1.58e-238	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
PKEHELCK_00269	9.56e-243	dhaK2	2.7.1.28, 2.7.1.29, 4.6.1.15	-	G	ko:K00863	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	ko00000,ko00001,ko00002,ko01000	Dak1 domain
PKEHELCK_00270	1.85e-121	XK27_02085	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PKEHELCK_00271	2.04e-99	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
PKEHELCK_00272	0.0	etfA	1.3.1.108	-	C	ko:K03522,ko:K22432	-	ko00000,ko01000,ko04147	Electron transfer flavoprotein FAD-binding domain
PKEHELCK_00273	8.03e-151	-	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
PKEHELCK_00274	0.0	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
PKEHELCK_00275	8.67e-168	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
PKEHELCK_00276	1.01e-184	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
PKEHELCK_00277	3.37e-115	-	-	-	-	-	-	-	-
PKEHELCK_00278	1.57e-191	-	-	-	-	-	-	-	-
PKEHELCK_00279	6.08e-180	-	-	-	-	-	-	-	-
PKEHELCK_00280	4.14e-72	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
PKEHELCK_00281	4.37e-167	-	-	-	K	ko:K03492	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
PKEHELCK_00283	2.57e-128	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
PKEHELCK_00284	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PKEHELCK_00285	3.28e-193	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
PKEHELCK_00286	6.49e-268	-	-	-	C	-	-	-	Oxidoreductase
PKEHELCK_00287	0.0	-	-	-	-	-	-	-	-
PKEHELCK_00288	4.29e-102	-	-	-	-	-	-	-	-
PKEHELCK_00289	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
PKEHELCK_00290	1.92e-106	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase like
PKEHELCK_00291	8.21e-213	-	1.1.1.65	-	C	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	ko00000,ko00001,ko01000	Aldo keto reductase
PKEHELCK_00292	2.16e-204	morA	-	-	S	-	-	-	reductase
PKEHELCK_00294	9.05e-136	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
PKEHELCK_00295	4.97e-114	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
PKEHELCK_00296	3.98e-68	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
PKEHELCK_00297	5.38e-290	-	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
PKEHELCK_00298	5.51e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
PKEHELCK_00299	3.99e-96	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
PKEHELCK_00300	1.27e-98	-	-	-	K	-	-	-	Transcriptional regulator
PKEHELCK_00301	7e-142	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
PKEHELCK_00302	2.92e-38	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
PKEHELCK_00303	1.34e-183	-	-	-	F	-	-	-	Phosphorylase superfamily
PKEHELCK_00304	0.0	pacL1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
PKEHELCK_00305	9.93e-127	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
PKEHELCK_00306	2.81e-64	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PKEHELCK_00307	1.23e-199	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PKEHELCK_00308	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
PKEHELCK_00309	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
PKEHELCK_00310	5.08e-192	-	-	-	I	-	-	-	Alpha/beta hydrolase family
PKEHELCK_00311	1.27e-159	-	-	-	-	-	-	-	-
PKEHELCK_00312	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
PKEHELCK_00313	5.04e-109	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
PKEHELCK_00314	0.0	-	-	-	L	-	-	-	HIRAN domain
PKEHELCK_00315	1.02e-175	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
PKEHELCK_00316	4.15e-261	thiP	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
PKEHELCK_00317	1.48e-140	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
PKEHELCK_00318	1.18e-188	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
PKEHELCK_00319	1.08e-174	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
PKEHELCK_00320	1.23e-227	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
PKEHELCK_00321	5.24e-193	larE	-	-	S	ko:K06864	-	ko00000	NAD synthase
PKEHELCK_00322	1.19e-170	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
PKEHELCK_00323	6.32e-99	larC2	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Protein of unknown function DUF111
PKEHELCK_00324	2.03e-179	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
PKEHELCK_00325	2.65e-162	larB	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
PKEHELCK_00326	7.9e-306	larA	5.1.2.1	-	S	ko:K22373	ko00620,map00620	ko00000,ko00001,ko01000	Domain of unknown function (DUF2088)
PKEHELCK_00327	1.39e-156	rcfB	-	-	K	-	-	-	Crp-like helix-turn-helix domain
PKEHELCK_00328	1.84e-235	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
PKEHELCK_00329	9.79e-192	-	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
PKEHELCK_00330	4.29e-166	-	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PKEHELCK_00331	1.67e-54	-	-	-	-	-	-	-	-
PKEHELCK_00332	1.56e-183	ant1	2.7.7.47	-	H	ko:K00984	-	ko00000,ko01000,ko01504	Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
PKEHELCK_00333	4.07e-05	-	-	-	-	-	-	-	-
PKEHELCK_00334	2.4e-180	-	-	-	-	-	-	-	-
PKEHELCK_00335	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
PKEHELCK_00336	2.38e-99	-	-	-	-	-	-	-	-
PKEHELCK_00337	7.76e-181	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
PKEHELCK_00338	9.01e-215	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
PKEHELCK_00339	3.83e-297	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
PKEHELCK_00340	1.02e-63	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
PKEHELCK_00341	3.14e-230	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
PKEHELCK_00342	1.4e-162	-	-	-	S	-	-	-	DJ-1/PfpI family
PKEHELCK_00343	7.65e-121	yfbM	-	-	K	-	-	-	FR47-like protein
PKEHELCK_00344	7.1e-194	-	-	-	EG	-	-	-	EamA-like transporter family
PKEHELCK_00345	2.84e-81	-	-	-	S	-	-	-	Protein of unknown function
PKEHELCK_00346	7.44e-51	-	-	-	S	-	-	-	Protein of unknown function
PKEHELCK_00347	0.0	fusA1	-	-	J	-	-	-	elongation factor G
PKEHELCK_00348	1.63e-152	azoR	-	-	C	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PKEHELCK_00349	1.67e-220	-	-	-	K	-	-	-	WYL domain
PKEHELCK_00350	4.35e-165	-	-	-	F	-	-	-	glutamine amidotransferase
PKEHELCK_00351	3.21e-104	-	-	-	S	-	-	-	ASCH
PKEHELCK_00352	0.0	hpaH	1.14.14.8, 1.14.14.9	-	Q	ko:K00483,ko:K16901	ko00350,ko00380,ko01120,ko01220,map00350,map00380,map01120,map01220	ko00000,ko00001,ko01000	4-hydroxyphenylacetate
PKEHELCK_00353	6.86e-175	ptp1	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
PKEHELCK_00354	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
PKEHELCK_00355	1.48e-246	pva1	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
PKEHELCK_00356	9.02e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
PKEHELCK_00357	0.0	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
PKEHELCK_00358	5.07e-157	ydgI	-	-	C	-	-	-	Nitroreductase family
PKEHELCK_00359	5.74e-204	adc	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
PKEHELCK_00360	4.06e-211	-	-	-	S	-	-	-	KR domain
PKEHELCK_00361	4.48e-98	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PKEHELCK_00362	2.49e-95	-	-	-	C	-	-	-	FMN binding
PKEHELCK_00363	1.46e-204	-	-	-	K	-	-	-	LysR family
PKEHELCK_00364	1.47e-290	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
PKEHELCK_00365	0.0	-	-	-	C	-	-	-	FMN_bind
PKEHELCK_00366	1.57e-150	-	-	-	S	-	-	-	Elongation factor G-binding protein, N-terminal
PKEHELCK_00367	4.95e-86	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
PKEHELCK_00368	1.34e-153	pnb	-	-	C	-	-	-	nitroreductase
PKEHELCK_00369	5.97e-157	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
PKEHELCK_00370	8.48e-215	-	-	-	L	-	-	-	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
PKEHELCK_00371	0.0	-	-	-	C	-	-	-	Belongs to the aldehyde dehydrogenase family
PKEHELCK_00372	3.46e-124	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PKEHELCK_00373	6.08e-107	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PKEHELCK_00374	1.5e-253	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
PKEHELCK_00375	1.71e-200	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
PKEHELCK_00376	3.54e-195	yycI	-	-	S	-	-	-	YycH protein
PKEHELCK_00377	3.4e-311	yycH	-	-	S	-	-	-	YycH protein
PKEHELCK_00378	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PKEHELCK_00379	2.22e-169	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
PKEHELCK_00381	2.54e-50	-	-	-	-	-	-	-	-
PKEHELCK_00382	4.37e-43	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein domain
PKEHELCK_00383	1.08e-102	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase
PKEHELCK_00384	0.0	trePP	2.4.1.216, 2.4.1.8	GH65	G	ko:K00691,ko:K03731	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65 central catalytic domain
PKEHELCK_00385	1.1e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
PKEHELCK_00386	2.4e-183	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
PKEHELCK_00388	0.0	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
PKEHELCK_00389	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
PKEHELCK_00390	0.0	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
PKEHELCK_00391	2.02e-268	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
PKEHELCK_00392	5.02e-277	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PKEHELCK_00393	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PKEHELCK_00394	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
PKEHELCK_00396	1.88e-291	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PKEHELCK_00397	9e-184	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PKEHELCK_00398	2.87e-288	yttB	-	-	EGP	-	-	-	Major Facilitator
PKEHELCK_00399	8.77e-317	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
PKEHELCK_00400	3.44e-95	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
PKEHELCK_00401	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
PKEHELCK_00402	2.69e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PKEHELCK_00403	1.59e-95	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PKEHELCK_00404	5.95e-65	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
PKEHELCK_00405	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PKEHELCK_00406	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PKEHELCK_00407	7.24e-263	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PKEHELCK_00408	3.82e-51	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
PKEHELCK_00409	8.19e-267	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
PKEHELCK_00410	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PKEHELCK_00411	3.74e-75	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
PKEHELCK_00412	1.55e-158	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PKEHELCK_00413	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
PKEHELCK_00414	2.26e-306	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
PKEHELCK_00415	2.37e-173	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
PKEHELCK_00416	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PKEHELCK_00417	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
PKEHELCK_00418	9.77e-64	-	-	-	S	-	-	-	Cell surface protein
PKEHELCK_00419	7.89e-130	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
PKEHELCK_00420	8.81e-205	-	-	-	S	-	-	-	Alpha beta hydrolase
PKEHELCK_00421	1.39e-143	-	-	-	GM	-	-	-	NmrA-like family
PKEHELCK_00422	1.74e-101	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2255)
PKEHELCK_00423	5.72e-207	-	-	-	K	-	-	-	Transcriptional regulator
PKEHELCK_00424	3.78e-221	cryZ	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
PKEHELCK_00426	0.0	nox4	-	-	C	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
PKEHELCK_00427	1.51e-132	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
PKEHELCK_00428	1.71e-264	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PKEHELCK_00429	1.27e-174	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
PKEHELCK_00430	4.17e-204	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
PKEHELCK_00432	6.64e-109	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
PKEHELCK_00433	5.53e-94	-	-	-	K	-	-	-	MarR family
PKEHELCK_00434	7.38e-148	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
PKEHELCK_00435	0.000138	yjdF	-	-	S	-	-	-	Protein of unknown function (DUF2992)
PKEHELCK_00436	1.77e-207	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PKEHELCK_00437	2.02e-168	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
PKEHELCK_00438	1.74e-252	-	-	-	-	-	-	-	-
PKEHELCK_00439	4.59e-133	-	-	-	-	-	-	-	-
PKEHELCK_00440	7.71e-104	-	-	-	-	-	-	-	-
PKEHELCK_00441	4.94e-213	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PKEHELCK_00442	1.18e-85	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
PKEHELCK_00443	1.74e-251	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PKEHELCK_00444	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PKEHELCK_00445	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
PKEHELCK_00446	3.52e-223	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
PKEHELCK_00447	2.84e-189	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
PKEHELCK_00448	7.92e-217	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PKEHELCK_00449	1.15e-94	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
PKEHELCK_00450	7.7e-110	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PKEHELCK_00451	4.81e-229	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
PKEHELCK_00452	9.21e-94	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
PKEHELCK_00453	1.09e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
PKEHELCK_00454	2.32e-194	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
PKEHELCK_00455	1.22e-164	-	-	-	C	-	-	-	Enoyl-(Acyl carrier protein) reductase
PKEHELCK_00456	1.42e-217	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
PKEHELCK_00457	1.84e-284	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
PKEHELCK_00458	4.35e-204	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PKEHELCK_00459	2.61e-132	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PKEHELCK_00460	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
PKEHELCK_00461	2.47e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
PKEHELCK_00462	4.01e-200	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
PKEHELCK_00463	1.47e-210	-	-	-	G	-	-	-	Fructosamine kinase
PKEHELCK_00464	2.43e-150	yjcF	-	-	J	-	-	-	HAD-hyrolase-like
PKEHELCK_00465	8.2e-102	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PKEHELCK_00466	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PKEHELCK_00467	2.56e-76	-	-	-	-	-	-	-	-
PKEHELCK_00468	3.13e-172	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
PKEHELCK_00469	2.04e-226	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
PKEHELCK_00470	5.28e-146	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
PKEHELCK_00471	4.78e-65	-	-	-	-	-	-	-	-
PKEHELCK_00472	1.73e-67	-	-	-	-	-	-	-	-
PKEHELCK_00475	1.01e-158	int7	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PKEHELCK_00476	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PKEHELCK_00477	6.83e-312	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PKEHELCK_00478	5.75e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PKEHELCK_00479	1.14e-297	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
PKEHELCK_00480	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PKEHELCK_00481	8.59e-27	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
PKEHELCK_00482	8.49e-266	pbpX2	-	-	V	-	-	-	Beta-lactamase
PKEHELCK_00483	2.54e-266	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PKEHELCK_00484	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
PKEHELCK_00485	4.52e-111	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PKEHELCK_00486	4.42e-248	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PKEHELCK_00487	1.19e-169	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
PKEHELCK_00488	6.21e-241	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
PKEHELCK_00489	8.94e-221	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PKEHELCK_00490	2.41e-113	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PKEHELCK_00491	1.47e-246	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
PKEHELCK_00492	1.24e-297	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
PKEHELCK_00493	1.63e-121	-	-	-	-	-	-	-	-
PKEHELCK_00494	3.67e-275	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PKEHELCK_00495	0.0	-	-	-	G	-	-	-	Major Facilitator
PKEHELCK_00496	4.32e-71	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PKEHELCK_00497	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PKEHELCK_00498	3.28e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
PKEHELCK_00499	2.95e-65	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
PKEHELCK_00500	2.58e-274	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
PKEHELCK_00501	9.74e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
PKEHELCK_00502	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PKEHELCK_00503	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PKEHELCK_00504	4.64e-294	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
PKEHELCK_00505	1.13e-175	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
PKEHELCK_00506	3.17e-190	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PKEHELCK_00507	9.83e-113	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PKEHELCK_00508	4.99e-164	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
PKEHELCK_00509	1.88e-194	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PKEHELCK_00510	7.39e-184	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
PKEHELCK_00511	8.37e-172	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
PKEHELCK_00512	7.82e-239	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PKEHELCK_00513	5.67e-64	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
PKEHELCK_00514	4.26e-171	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
PKEHELCK_00515	8.8e-155	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
PKEHELCK_00516	3.96e-44	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
PKEHELCK_00517	3.13e-47	ynzC	-	-	S	-	-	-	UPF0291 protein
PKEHELCK_00518	7.22e-149	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PKEHELCK_00519	7.8e-123	-	-	-	-	-	-	-	-
PKEHELCK_00520	1.56e-276	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
PKEHELCK_00521	1.38e-98	-	-	-	-	-	-	-	-
PKEHELCK_00522	3.81e-87	-	-	-	-	-	-	-	-
PKEHELCK_00523	1.14e-226	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyltransferase like family 2
PKEHELCK_00524	2.19e-131	-	-	-	L	-	-	-	Helix-turn-helix domain
PKEHELCK_00525	3.57e-241	ywtF_2	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
PKEHELCK_00526	0.0	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PKEHELCK_00527	7.97e-293	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Cell cycle protein
PKEHELCK_00529	3.96e-50	-	-	-	S	-	-	-	Bacteriophage holin
PKEHELCK_00530	7.53e-40	-	-	-	S	-	-	-	Haemolysin XhlA
PKEHELCK_00531	2.48e-182	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
PKEHELCK_00532	5.85e-70	-	-	-	-	-	-	-	-
PKEHELCK_00535	1.23e-61	-	-	-	-	-	-	-	-
PKEHELCK_00536	0.0	-	-	-	S	-	-	-	Phage minor structural protein
PKEHELCK_00537	0.0	-	-	-	S	-	-	-	Phage tail protein
PKEHELCK_00538	1.23e-263	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
PKEHELCK_00540	1.5e-18	-	-	-	S	-	-	-	Phage tail assembly chaperone proteins, TAC
PKEHELCK_00541	1.77e-94	-	-	-	S	-	-	-	Phage tail tube protein
PKEHELCK_00542	6.2e-31	-	-	-	S	-	-	-	Protein of unknown function (DUF806)
PKEHELCK_00543	9.2e-37	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
PKEHELCK_00544	7.79e-18	-	-	-	S	-	-	-	Phage head-tail joining protein
PKEHELCK_00545	5.83e-31	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
PKEHELCK_00546	4.69e-148	-	-	-	S	-	-	-	Phage capsid family
PKEHELCK_00547	3.49e-102	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
PKEHELCK_00548	1.72e-180	-	-	-	S	-	-	-	Phage portal protein
PKEHELCK_00550	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
PKEHELCK_00551	7.16e-51	-	-	-	L	-	-	-	Phage terminase, small subunit
PKEHELCK_00552	4.94e-79	-	-	-	V	-	-	-	HNH nucleases
PKEHELCK_00554	4.21e-13	-	-	-	V	-	-	-	HNH nucleases
PKEHELCK_00556	9.31e-84	-	-	-	S	-	-	-	Transcriptional regulator, RinA family
PKEHELCK_00557	1.09e-23	-	-	-	-	-	-	-	-
PKEHELCK_00559	1.32e-39	-	-	-	S	-	-	-	YopX protein
PKEHELCK_00562	4.14e-20	-	-	-	-	-	-	-	-
PKEHELCK_00563	4.52e-36	-	-	-	-	-	-	-	-
PKEHELCK_00564	1.86e-210	nanA	4.1.3.3	-	EM	ko:K01639	ko00520,map00520	ko00000,ko00001,ko01000	Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
PKEHELCK_00565	4.66e-197	nanK	-	-	GK	-	-	-	ROK family
PKEHELCK_00566	9.03e-173	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
PKEHELCK_00567	4.01e-263	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
PKEHELCK_00568	0.0	-	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PKEHELCK_00569	3.89e-205	-	-	-	I	-	-	-	alpha/beta hydrolase fold
PKEHELCK_00570	2.56e-175	-	-	-	I	-	-	-	alpha/beta hydrolase fold
PKEHELCK_00571	3.08e-93	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
PKEHELCK_00572	8.85e-179	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
PKEHELCK_00573	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
PKEHELCK_00574	3.03e-145	-	-	-	K	ko:K02444	-	ko00000,ko03000	DeoR C terminal sensor domain
PKEHELCK_00575	3.99e-106	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PKEHELCK_00576	6e-60	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
PKEHELCK_00577	8.37e-296	gatC	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
PKEHELCK_00578	5.26e-247	-	1.1.1.14	-	C	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
PKEHELCK_00579	9.14e-146	gph3	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
PKEHELCK_00580	0.0	-	-	-	G	ko:K03483	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PKEHELCK_00581	1.58e-101	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PKEHELCK_00582	7.29e-61	ulaB	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system galactitol-specific IIB component
PKEHELCK_00583	1.17e-305	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
PKEHELCK_00584	1.02e-147	tal	2.2.1.2	-	F	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PKEHELCK_00585	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PKEHELCK_00586	1.74e-184	yxeH	-	-	S	-	-	-	hydrolase
PKEHELCK_00587	1.91e-235	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
PKEHELCK_00589	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
PKEHELCK_00590	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
PKEHELCK_00591	1.08e-221	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
PKEHELCK_00592	0.0	treP	2.4.1.64	GH65	G	ko:K05342	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
PKEHELCK_00593	2.58e-122	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
PKEHELCK_00594	4.37e-63	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
PKEHELCK_00595	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PKEHELCK_00596	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
PKEHELCK_00597	0.0	pbg9	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
PKEHELCK_00598	3.72e-200	bglG4	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
PKEHELCK_00599	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PKEHELCK_00600	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
PKEHELCK_00601	2.26e-269	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
PKEHELCK_00602	2.4e-202	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
PKEHELCK_00603	1.02e-210	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
PKEHELCK_00604	1.87e-316	pts29C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PKEHELCK_00605	5.44e-174	-	-	-	K	-	-	-	UTRA domain
PKEHELCK_00606	2.63e-200	estA	-	-	S	-	-	-	Putative esterase
PKEHELCK_00607	2.01e-81	-	-	-	-	-	-	-	-
PKEHELCK_00608	1.12e-262	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
PKEHELCK_00609	1.73e-215	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
PKEHELCK_00610	4.57e-211	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
PKEHELCK_00611	1.64e-202	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
PKEHELCK_00612	8.13e-206	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PKEHELCK_00613	1.71e-207	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PKEHELCK_00614	1.4e-282	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
PKEHELCK_00615	4.62e-224	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
PKEHELCK_00616	3.21e-212	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PKEHELCK_00617	1.49e-171	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
PKEHELCK_00618	1.23e-228	apbE3	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PKEHELCK_00619	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
PKEHELCK_00620	2.02e-85	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
PKEHELCK_00621	3.63e-248	tas3	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
PKEHELCK_00622	3.69e-232	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
PKEHELCK_00623	4.27e-253	galM3	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
PKEHELCK_00624	0.0	lacP	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
PKEHELCK_00625	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
PKEHELCK_00626	1.64e-238	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
PKEHELCK_00627	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
PKEHELCK_00628	1.65e-286	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PKEHELCK_00629	1.26e-245	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
PKEHELCK_00630	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
PKEHELCK_00631	1.19e-234	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
PKEHELCK_00632	3.4e-100	-	-	-	K	ko:K07726	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
PKEHELCK_00633	6.22e-140	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
PKEHELCK_00634	5.27e-235	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
PKEHELCK_00635	5.06e-298	-	-	-	P	ko:K06610	-	ko00000,ko02000	Major Facilitator Superfamily
PKEHELCK_00636	0.0	ram2	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
PKEHELCK_00637	5.02e-294	-	-	-	P	ko:K06610	-	ko00000,ko02000	Sugar (and other) transporter
PKEHELCK_00638	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
PKEHELCK_00639	1.13e-228	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein-like domain
PKEHELCK_00640	1.2e-295	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PKEHELCK_00641	2.81e-90	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
PKEHELCK_00642	0.0	rafA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
PKEHELCK_00643	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
PKEHELCK_00644	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
PKEHELCK_00645	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
PKEHELCK_00646	1.95e-140	aqpZ	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
PKEHELCK_00647	3.31e-282	-	-	-	S	-	-	-	associated with various cellular activities
PKEHELCK_00648	9.34e-317	-	-	-	S	-	-	-	Putative metallopeptidase domain
PKEHELCK_00649	1.03e-65	-	-	-	-	-	-	-	-
PKEHELCK_00650	8.19e-134	yezE	-	-	K	ko:K16137	-	ko00000,ko03000	Bacterial regulatory proteins, tetR family
PKEHELCK_00651	7.83e-60	-	-	-	-	-	-	-	-
PKEHELCK_00652	4.23e-129	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
PKEHELCK_00653	8.67e-160	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
PKEHELCK_00654	1.83e-235	-	-	-	S	-	-	-	Cell surface protein
PKEHELCK_00655	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
PKEHELCK_00656	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
PKEHELCK_00657	1.23e-105	yoaA	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PKEHELCK_00658	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
PKEHELCK_00659	1.82e-152	rcfA	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
PKEHELCK_00660	2.98e-44	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
PKEHELCK_00661	4.27e-126	dpsB	-	-	P	-	-	-	Belongs to the Dps family
PKEHELCK_00662	1.01e-26	-	-	-	-	-	-	-	-
PKEHELCK_00663	4.82e-55	yrkD	-	-	S	-	-	-	Metal-sensitive transcriptional repressor
PKEHELCK_00664	2.34e-72	trxA3	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin-like domain
PKEHELCK_00665	3.29e-183	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
PKEHELCK_00666	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
PKEHELCK_00667	1.98e-232	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
PKEHELCK_00668	1.5e-165	-	-	-	S	-	-	-	Gram-negative-bacterium-type cell wall biogenesis
PKEHELCK_00669	3.42e-174	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
PKEHELCK_00670	5.65e-229	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
PKEHELCK_00671	1.12e-134	-	-	-	K	-	-	-	transcriptional regulator
PKEHELCK_00673	9.39e-84	-	-	-	-	-	-	-	-
PKEHELCK_00675	5.77e-81	-	-	-	-	-	-	-	-
PKEHELCK_00676	6.18e-71	-	-	-	-	-	-	-	-
PKEHELCK_00677	4.25e-98	-	-	-	M	-	-	-	PFAM NLP P60 protein
PKEHELCK_00678	0.0	gadB	4.1.1.15, 4.1.2.27	-	E	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Belongs to the group II decarboxylase family
PKEHELCK_00679	4.45e-38	-	-	-	-	-	-	-	-
PKEHELCK_00680	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
PKEHELCK_00681	3.81e-150	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PKEHELCK_00682	5.33e-114	-	-	-	K	-	-	-	Winged helix DNA-binding domain
PKEHELCK_00683	1.9e-260	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
PKEHELCK_00684	1.33e-77	-	-	-	-	-	-	-	-
PKEHELCK_00685	5.37e-182	-	-	-	-	-	-	-	-
PKEHELCK_00686	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
PKEHELCK_00687	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
PKEHELCK_00688	5.63e-89	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
PKEHELCK_00689	4.66e-167	icaB	-	-	G	-	-	-	Polysaccharide deacetylase
PKEHELCK_00691	2.18e-207	-	-	-	K	-	-	-	IrrE N-terminal-like domain
PKEHELCK_00692	1.32e-120	-	-	-	-	-	-	-	-
PKEHELCK_00693	2.78e-54	-	-	-	S	-	-	-	Bacteriophage holin
PKEHELCK_00694	5.33e-63	-	-	-	-	-	-	-	-
PKEHELCK_00695	2.87e-220	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
PKEHELCK_00696	5.07e-09	xhlB	-	-	S	-	-	-	SPP1 phage holin
PKEHELCK_00698	2.46e-47	-	-	-	-	-	-	-	-
PKEHELCK_00699	1.7e-103	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
PKEHELCK_00702	5.71e-123	-	-	-	S	-	-	-	Prophage endopeptidase tail
PKEHELCK_00704	1.08e-179	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
PKEHELCK_00707	4.77e-56	-	-	-	N	-	-	-	domain, Protein
PKEHELCK_00712	5.98e-06	-	-	-	-	-	-	-	-
PKEHELCK_00713	8.59e-136	-	-	-	-	-	-	-	-
PKEHELCK_00715	1.1e-53	-	-	-	S	-	-	-	Phage minor capsid protein 2
PKEHELCK_00716	2.67e-137	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
PKEHELCK_00717	4.02e-234	-	-	-	S	-	-	-	Phage terminase, large subunit, PBSX family
PKEHELCK_00718	4.09e-51	-	-	-	-	-	-	-	-
PKEHELCK_00720	9e-24	-	-	-	-	-	-	-	-
PKEHELCK_00721	1.41e-85	-	-	-	K	-	-	-	IrrE N-terminal-like domain
PKEHELCK_00722	7.19e-95	-	-	-	-	-	-	-	-
PKEHELCK_00723	1.39e-55	-	-	-	-	-	-	-	-
PKEHELCK_00725	1.51e-22	-	-	-	S	-	-	-	KTSC domain
PKEHELCK_00728	3.71e-105	-	-	-	S	-	-	-	Phage transcriptional regulator, ArpU family
PKEHELCK_00729	5.18e-08	-	-	-	-	-	-	-	-
PKEHELCK_00730	5.7e-87	-	-	-	L	-	-	-	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
PKEHELCK_00731	7.46e-80	-	-	-	-	-	-	-	-
PKEHELCK_00732	2.67e-66	-	-	-	-	-	-	-	-
PKEHELCK_00733	2.61e-206	-	-	-	L	-	-	-	DnaD domain protein
PKEHELCK_00734	4.4e-173	pi112	-	-	L	-	-	-	PDDEXK-like domain of unknown function (DUF3799)
PKEHELCK_00735	5.03e-197	-	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
PKEHELCK_00736	9e-89	-	-	-	-	-	-	-	-
PKEHELCK_00738	3.09e-94	-	-	-	-	-	-	-	-
PKEHELCK_00739	1.5e-68	-	-	-	-	-	-	-	-
PKEHELCK_00742	1.26e-26	-	-	-	S	-	-	-	protein disulfide oxidoreductase activity
PKEHELCK_00746	2.24e-19	-	-	-	S	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
PKEHELCK_00751	1.93e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF3037)
PKEHELCK_00752	8.03e-280	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PKEHELCK_00754	8.08e-40	-	-	-	-	-	-	-	-
PKEHELCK_00756	1.28e-51	-	-	-	-	-	-	-	-
PKEHELCK_00757	1.09e-56	-	-	-	-	-	-	-	-
PKEHELCK_00758	1.27e-109	-	-	-	K	-	-	-	MarR family
PKEHELCK_00759	0.0	-	-	-	D	-	-	-	nuclear chromosome segregation
PKEHELCK_00760	0.0	inlJ	-	-	M	-	-	-	MucBP domain
PKEHELCK_00761	6.58e-24	-	-	-	-	-	-	-	-
PKEHELCK_00762	3.26e-24	-	-	-	-	-	-	-	-
PKEHELCK_00763	1.56e-22	-	-	-	-	-	-	-	-
PKEHELCK_00764	1.07e-26	-	-	-	-	-	-	-	-
PKEHELCK_00765	9.35e-24	-	-	-	-	-	-	-	-
PKEHELCK_00766	9.35e-24	-	-	-	-	-	-	-	-
PKEHELCK_00767	9.35e-24	-	-	-	-	-	-	-	-
PKEHELCK_00768	2.16e-26	-	-	-	-	-	-	-	-
PKEHELCK_00769	4.63e-24	-	-	-	-	-	-	-	-
PKEHELCK_00770	0.0	-	3.6.3.44	-	P	ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter transmembrane region
PKEHELCK_00771	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
PKEHELCK_00772	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PKEHELCK_00773	2.1e-33	-	-	-	-	-	-	-	-
PKEHELCK_00774	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
PKEHELCK_00775	2.51e-200	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
PKEHELCK_00776	1.83e-277	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
PKEHELCK_00777	0.0	yclK	-	-	T	-	-	-	Histidine kinase
PKEHELCK_00778	1.45e-173	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
PKEHELCK_00779	2.12e-308	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
PKEHELCK_00780	6.12e-51	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
PKEHELCK_00781	1.26e-218	-	-	-	EG	-	-	-	EamA-like transporter family
PKEHELCK_00783	6.24e-120	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
PKEHELCK_00784	1.31e-64	-	-	-	-	-	-	-	-
PKEHELCK_00785	1.32e-271	yceI	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major Facilitator
PKEHELCK_00786	8.05e-178	-	-	-	F	-	-	-	NUDIX domain
PKEHELCK_00787	2.68e-32	-	-	-	-	-	-	-	-
PKEHELCK_00789	2e-207	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
PKEHELCK_00790	2.47e-222	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	NlpC/P60 family
PKEHELCK_00791	5.92e-107	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
PKEHELCK_00792	2.29e-48	-	-	-	-	-	-	-	-
PKEHELCK_00793	1.11e-45	-	-	-	-	-	-	-	-
PKEHELCK_00794	2.58e-274	-	-	-	T	-	-	-	diguanylate cyclase
PKEHELCK_00795	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
PKEHELCK_00796	3.1e-138	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
PKEHELCK_00797	3.9e-105	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PKEHELCK_00798	9.2e-62	-	-	-	-	-	-	-	-
PKEHELCK_00799	0.0	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
PKEHELCK_00800	4.37e-241	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PKEHELCK_00801	3.45e-209	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
PKEHELCK_00802	1.01e-293	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
PKEHELCK_00803	6.08e-312	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
PKEHELCK_00804	1.53e-213	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
PKEHELCK_00805	1.13e-225	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
PKEHELCK_00806	7.03e-195	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
PKEHELCK_00807	1.55e-177	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PKEHELCK_00808	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
PKEHELCK_00809	9.51e-203	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
PKEHELCK_00810	1.01e-176	yceF	-	-	P	ko:K05794	-	ko00000	membrane
PKEHELCK_00811	4.99e-125	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
PKEHELCK_00812	4.48e-257	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PKEHELCK_00813	1.07e-68	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
PKEHELCK_00814	6.12e-78	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PKEHELCK_00815	1.27e-172	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
PKEHELCK_00816	6.84e-166	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PKEHELCK_00817	2.23e-142	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PKEHELCK_00818	2.46e-139	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
PKEHELCK_00819	1.92e-299	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PKEHELCK_00820	1.69e-151	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
PKEHELCK_00821	4.44e-273	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
PKEHELCK_00822	1.3e-207	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphate phosphatase, HisJ
PKEHELCK_00823	2.93e-280	ysaA	-	-	V	-	-	-	RDD family
PKEHELCK_00824	7.28e-213	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
PKEHELCK_00825	6.7e-74	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
PKEHELCK_00826	4.73e-118	rmeB	-	-	K	-	-	-	transcriptional regulator, MerR family
PKEHELCK_00827	2.49e-190	-	-	-	GM	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
PKEHELCK_00828	4.54e-126	-	-	-	J	-	-	-	glyoxalase III activity
PKEHELCK_00829	1.69e-255	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PKEHELCK_00830	9.88e-239	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
PKEHELCK_00831	1.45e-46	-	-	-	-	-	-	-	-
PKEHELCK_00832	7.3e-143	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
PKEHELCK_00833	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
PKEHELCK_00834	0.0	-	-	-	M	-	-	-	domain protein
PKEHELCK_00835	3e-98	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
PKEHELCK_00836	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PKEHELCK_00837	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
PKEHELCK_00838	7.1e-31	-	-	-	K	-	-	-	Helix-turn-helix domain
PKEHELCK_00839	1.92e-115	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
PKEHELCK_00840	2.5e-66	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
PKEHELCK_00841	7.85e-114	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PKEHELCK_00842	6.79e-53	-	-	-	-	-	-	-	-
PKEHELCK_00843	5.06e-168	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PKEHELCK_00844	4.59e-233	ydbI	-	-	K	-	-	-	AI-2E family transporter
PKEHELCK_00845	7.62e-270	xylR	-	-	GK	-	-	-	ROK family
PKEHELCK_00846	2.92e-143	-	-	-	-	-	-	-	-
PKEHELCK_00847	3.66e-295	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
PKEHELCK_00848	9.51e-210	-	-	-	-	-	-	-	-
PKEHELCK_00849	1.86e-256	pkn2	-	-	KLT	-	-	-	Protein tyrosine kinase
PKEHELCK_00850	1.75e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF4064)
PKEHELCK_00851	2.47e-125	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
PKEHELCK_00852	5.61e-98	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
PKEHELCK_00853	6.09e-72	-	-	-	-	-	-	-	-
PKEHELCK_00854	3.37e-141	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
PKEHELCK_00855	2.42e-72	-	-	-	S	-	-	-	branched-chain amino acid
PKEHELCK_00856	4.83e-166	-	-	-	E	-	-	-	branched-chain amino acid
PKEHELCK_00857	6.77e-116	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
PKEHELCK_00858	3.61e-303	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
PKEHELCK_00859	5.61e-273	hpk31	-	-	T	-	-	-	Histidine kinase
PKEHELCK_00860	1.14e-159	vanR	-	-	K	-	-	-	response regulator
PKEHELCK_00861	1.39e-160	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
PKEHELCK_00862	3.3e-208	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
PKEHELCK_00863	3.49e-270	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PKEHELCK_00864	3.49e-160	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
PKEHELCK_00865	6.6e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PKEHELCK_00866	1.4e-40	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
PKEHELCK_00867	7.16e-201	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
PKEHELCK_00868	1.01e-175	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
PKEHELCK_00869	4.99e-190	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
PKEHELCK_00870	1.81e-168	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
PKEHELCK_00871	1.66e-288	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Nucleoside
PKEHELCK_00872	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
PKEHELCK_00873	1.15e-143	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
PKEHELCK_00874	7.86e-66	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
PKEHELCK_00875	3.18e-65	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
PKEHELCK_00876	1.37e-215	-	-	-	K	-	-	-	LysR substrate binding domain
PKEHELCK_00877	2.07e-302	-	-	-	EK	-	-	-	Aminotransferase, class I
PKEHELCK_00878	2.13e-167	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
PKEHELCK_00879	2.11e-158	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PKEHELCK_00880	3.02e-176	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PKEHELCK_00881	2.17e-162	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
PKEHELCK_00882	1.07e-127	-	-	-	KT	-	-	-	response to antibiotic
PKEHELCK_00883	2.86e-68	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator
PKEHELCK_00884	1.73e-132	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
PKEHELCK_00885	1.13e-200	-	-	-	S	-	-	-	Putative adhesin
PKEHELCK_00886	0.0	pts26BCA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PKEHELCK_00887	0.0	malL	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
PKEHELCK_00888	6.12e-232	purR2	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
PKEHELCK_00889	3.73e-263	-	-	-	S	-	-	-	DUF218 domain
PKEHELCK_00890	2.44e-165	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
PKEHELCK_00891	2.93e-151	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PKEHELCK_00892	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PKEHELCK_00893	6.26e-101	-	-	-	-	-	-	-	-
PKEHELCK_00894	6.34e-193	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
PKEHELCK_00895	3.54e-190	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
PKEHELCK_00896	2.24e-116	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
PKEHELCK_00897	0.0	mngB	3.2.1.170	GH38	G	ko:K15524	-	ko00000,ko01000	Glycosyl hydrolases family 38 N-terminal domain
PKEHELCK_00898	6.69e-155	fptC	-	-	U	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase system, EIIC
PKEHELCK_00899	2.52e-35	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
PKEHELCK_00900	5.55e-22	-	-	-	G	ko:K11203	-	ko00000,ko00002,ko02000	PTS system, fructose subfamily
PKEHELCK_00901	2.11e-104	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PKEHELCK_00902	4.08e-101	-	-	-	K	-	-	-	MerR family regulatory protein
PKEHELCK_00903	7.54e-200	-	-	-	GM	-	-	-	NmrA-like family
PKEHELCK_00904	0.0	pts28ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PKEHELCK_00905	5.08e-164	nth2	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
PKEHELCK_00907	8.66e-130	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
PKEHELCK_00908	3.43e-303	-	-	-	S	-	-	-	module of peptide synthetase
PKEHELCK_00909	7.27e-139	-	-	-	-	-	-	-	-
PKEHELCK_00910	1.55e-114	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
PKEHELCK_00911	1.28e-77	-	-	-	S	-	-	-	Enterocin A Immunity
PKEHELCK_00912	6.46e-49	-	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
PKEHELCK_00913	8.9e-146	-	3.1.4.17, 3.1.4.53	-	S	ko:K01120,ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
PKEHELCK_00914	3.98e-135	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
PKEHELCK_00915	9.76e-83	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
PKEHELCK_00916	2.88e-164	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
PKEHELCK_00917	3.84e-186	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
PKEHELCK_00918	1.03e-34	-	-	-	-	-	-	-	-
PKEHELCK_00919	1.48e-152	yugP	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
PKEHELCK_00920	0.0	-	1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31	-	Q	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	ko00000,ko00001,ko01000	Flavin containing amine oxidoreductase
PKEHELCK_00921	6.72e-209	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Squalene/phytoene synthase
PKEHELCK_00922	1.91e-234	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
PKEHELCK_00923	1.01e-251	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
PKEHELCK_00924	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
PKEHELCK_00925	1.69e-71	-	-	-	S	-	-	-	Enterocin A Immunity
PKEHELCK_00926	5.02e-313	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PKEHELCK_00927	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PKEHELCK_00928	4.17e-235	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PKEHELCK_00929	4.47e-181	amiF	-	-	E	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
PKEHELCK_00930	4.32e-240	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PKEHELCK_00931	6.22e-201	-	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PKEHELCK_00932	0.0	amiC	-	-	U	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PKEHELCK_00933	0.0	amiA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
PKEHELCK_00934	5.9e-187	ptp2	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
PKEHELCK_00935	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PKEHELCK_00937	4.62e-107	-	-	-	-	-	-	-	-
PKEHELCK_00938	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	C-terminus of AA_permease
PKEHELCK_00940	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
PKEHELCK_00941	1.07e-211	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PKEHELCK_00942	1.04e-226	ydbI	-	-	K	-	-	-	AI-2E family transporter
PKEHELCK_00943	9.89e-232	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
PKEHELCK_00944	1.15e-77	-	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
PKEHELCK_00945	1.97e-60	qacH	-	-	U	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
PKEHELCK_00946	2.94e-149	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
PKEHELCK_00947	7.27e-73	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
PKEHELCK_00948	1.3e-207	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
PKEHELCK_00949	6.62e-133	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PKEHELCK_00951	8.03e-28	-	-	-	-	-	-	-	-
PKEHELCK_00952	1.59e-123	tag2	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
PKEHELCK_00953	1.37e-271	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
PKEHELCK_00954	3.59e-130	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
PKEHELCK_00955	5.04e-315	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
PKEHELCK_00956	1.04e-133	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
PKEHELCK_00957	1.59e-121	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
PKEHELCK_00958	9.61e-84	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PKEHELCK_00959	4.08e-107	cvpA	-	-	S	-	-	-	Colicin V production protein
PKEHELCK_00960	5.61e-216	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
PKEHELCK_00961	8.83e-317	-	-	-	EGP	-	-	-	Major Facilitator
PKEHELCK_00963	4.54e-54	-	-	-	-	-	-	-	-
PKEHELCK_00975	3.26e-119	-	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Phosphoribosyl transferase domain
PKEHELCK_00976	6.36e-237	-	-	-	P	ko:K06901	-	ko00000,ko02000	secondary active sulfate transmembrane transporter activity
PKEHELCK_00977	2.07e-123	-	-	-	-	-	-	-	-
PKEHELCK_00978	1.58e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
PKEHELCK_00979	1.78e-201	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
PKEHELCK_00980	1.24e-144	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
PKEHELCK_00981	1.98e-184	lipA	-	-	I	-	-	-	Carboxylesterase family
PKEHELCK_00982	5.91e-208	-	-	-	P	-	-	-	Major Facilitator Superfamily
PKEHELCK_00983	5.42e-142	-	-	-	GK	-	-	-	ROK family
PKEHELCK_00984	3.26e-293	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
PKEHELCK_00985	2.42e-238	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
PKEHELCK_00986	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
PKEHELCK_00987	1.07e-213	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
PKEHELCK_00988	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
PKEHELCK_00989	6.75e-157	-	-	-	-	-	-	-	-
PKEHELCK_00990	2.78e-273	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PKEHELCK_00991	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
PKEHELCK_00992	2.62e-299	-	-	-	N	-	-	-	Cell shape-determining protein MreB
PKEHELCK_00993	6.56e-22	-	-	-	N	-	-	-	Cell shape-determining protein MreB
PKEHELCK_00994	0.0	-	-	-	S	-	-	-	Pfam Methyltransferase
PKEHELCK_00995	0.0	tagE2	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
PKEHELCK_00996	0.0	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
PKEHELCK_00997	9.32e-40	-	-	-	-	-	-	-	-
PKEHELCK_00998	3.03e-122	mraW1	-	-	J	-	-	-	Putative rRNA methylase
PKEHELCK_00999	2.95e-160	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
PKEHELCK_01000	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
PKEHELCK_01001	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
PKEHELCK_01002	5.04e-176	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
PKEHELCK_01003	3.03e-193	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PKEHELCK_01004	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
PKEHELCK_01005	3.07e-109	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
PKEHELCK_01006	3.56e-259	ugpC	3.6.3.20	-	E	ko:K05816,ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the ABC transporter superfamily
PKEHELCK_01007	2.56e-175	ugpA	-	-	U	ko:K02025,ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PKEHELCK_01008	6.16e-193	ugpE	-	-	G	ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PKEHELCK_01009	0.0	ugpB	-	-	G	ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
PKEHELCK_01010	5.45e-162	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
PKEHELCK_01011	2.07e-155	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
PKEHELCK_01012	3.55e-72	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
PKEHELCK_01013	2.75e-286	XK27_06930	-	-	V	ko:K01421	-	ko00000	domain protein
PKEHELCK_01015	1.16e-160	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
PKEHELCK_01016	3.06e-201	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
PKEHELCK_01017	2.57e-226	-	-	-	K	ko:K01990	-	ko00000,ko00002,ko02000	LytTr DNA-binding domain
PKEHELCK_01019	6.96e-198	mrsA1	1.8.4.11	-	O	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PKEHELCK_01020	5.2e-85	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
PKEHELCK_01021	1.64e-151	-	-	-	GM	-	-	-	NAD(P)H-binding
PKEHELCK_01022	9.36e-205	ydeD	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
PKEHELCK_01023	1.14e-190	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
PKEHELCK_01024	7.83e-140	-	-	-	-	-	-	-	-
PKEHELCK_01025	8.83e-285	pltK	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
PKEHELCK_01026	9.01e-179	agrA	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
PKEHELCK_01027	5.37e-74	-	-	-	-	-	-	-	-
PKEHELCK_01028	4.56e-78	-	-	-	-	-	-	-	-
PKEHELCK_01029	1.23e-145	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
PKEHELCK_01030	6.32e-111	ohrR	-	-	K	ko:K18906	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
PKEHELCK_01031	8.82e-119	-	-	-	-	-	-	-	-
PKEHELCK_01032	7.12e-62	-	-	-	-	-	-	-	-
PKEHELCK_01033	0.0	uvrA2	-	-	L	-	-	-	ABC transporter
PKEHELCK_01035	4.19e-118	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PKEHELCK_01042	1.32e-19	-	-	-	K	-	-	-	Helix-turn-helix
PKEHELCK_01043	2.84e-128	-	-	-	K	-	-	-	ORF6N domain
PKEHELCK_01044	3.08e-11	-	-	-	-	-	-	-	-
PKEHELCK_01045	6.21e-36	-	-	-	S	-	-	-	Domain of unknown function (DUF771)
PKEHELCK_01050	7.4e-52	-	-	-	S	-	-	-	Siphovirus Gp157
PKEHELCK_01051	2.86e-216	-	-	-	S	-	-	-	helicase activity
PKEHELCK_01052	2.08e-67	-	-	-	L	-	-	-	AAA domain
PKEHELCK_01053	4.97e-28	-	-	-	-	-	-	-	-
PKEHELCK_01054	1.26e-94	-	-	-	S	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
PKEHELCK_01055	3.67e-165	-	-	-	S	ko:K06919	-	ko00000	Virulence-associated protein E
PKEHELCK_01056	1.56e-51	-	-	-	S	-	-	-	hydrolase activity, acting on ester bonds
PKEHELCK_01057	9.67e-06	-	-	-	-	-	-	-	-
PKEHELCK_01062	1.63e-42	-	-	-	-	-	-	-	-
PKEHELCK_01066	4.99e-44	-	-	-	-	-	-	-	-
PKEHELCK_01069	1.52e-104	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
PKEHELCK_01074	3.41e-13	-	-	-	-	-	-	-	-
PKEHELCK_01075	2.36e-213	-	-	-	S	-	-	-	Terminase
PKEHELCK_01076	1.24e-128	-	-	-	S	-	-	-	Phage portal protein
PKEHELCK_01077	2.45e-72	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Clp protease
PKEHELCK_01078	1.72e-132	-	-	-	S	-	-	-	Phage capsid family
PKEHELCK_01079	6.56e-19	-	-	-	-	-	-	-	-
PKEHELCK_01080	6.11e-32	-	-	-	-	-	-	-	-
PKEHELCK_01081	1.28e-31	-	-	-	-	-	-	-	-
PKEHELCK_01082	4.57e-29	-	-	-	-	-	-	-	-
PKEHELCK_01083	1.07e-43	-	-	-	S	-	-	-	Phage tail tube protein
PKEHELCK_01085	3.22e-213	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
PKEHELCK_01088	4.02e-134	-	-	-	LM	-	-	-	DNA recombination
PKEHELCK_01089	3.36e-24	-	-	-	S	-	-	-	Protein of unknown function (DUF1617)
PKEHELCK_01091	5.29e-56	-	-	-	-	-	-	-	-
PKEHELCK_01093	1.78e-07	-	-	-	S	-	-	-	Bacteriophage A118-like holin, Hol118
PKEHELCK_01094	9.05e-141	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
PKEHELCK_01096	4.29e-87	-	-	-	-	-	-	-	-
PKEHELCK_01097	9.03e-16	-	-	-	-	-	-	-	-
PKEHELCK_01098	3.89e-237	-	-	-	-	-	-	-	-
PKEHELCK_01099	4.91e-117	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
PKEHELCK_01100	8.01e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1516)
PKEHELCK_01101	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
PKEHELCK_01102	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PKEHELCK_01103	0.0	-	-	-	S	-	-	-	Protein conserved in bacteria
PKEHELCK_01104	4.12e-148	sat	2.7.7.4	-	H	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
PKEHELCK_01105	7.45e-36	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
PKEHELCK_01106	9.8e-181	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
PKEHELCK_01107	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
PKEHELCK_01108	9.11e-208	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
PKEHELCK_01109	1.23e-58	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
PKEHELCK_01110	5.31e-242	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
PKEHELCK_01111	1.92e-264	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
PKEHELCK_01112	8.69e-230	citR	-	-	K	-	-	-	sugar-binding domain protein
PKEHELCK_01113	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
PKEHELCK_01114	9.2e-215	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
PKEHELCK_01115	1.18e-66	-	-	-	-	-	-	-	-
PKEHELCK_01116	5.19e-223	mntA	-	-	P	ko:K19975,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
PKEHELCK_01117	1.44e-179	mtsB	-	-	U	ko:K19972,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
PKEHELCK_01118	2.04e-170	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
PKEHELCK_01119	1.57e-196	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
PKEHELCK_01120	1.28e-253	-	-	-	K	-	-	-	Helix-turn-helix domain
PKEHELCK_01121	5.21e-226	ttdA	4.2.1.32	-	C	ko:K03779	ko00630,map00630	ko00000,ko00001,ko01000	Fumarate hydratase (Fumerase)
PKEHELCK_01122	1.41e-147	-	4.2.1.2, 4.2.1.32	-	C	ko:K01676,ko:K03780	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible hydration of fumarate to (S)- malate
PKEHELCK_01123	4.33e-69	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
PKEHELCK_01124	0.0	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
PKEHELCK_01125	5.89e-137	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PKEHELCK_01126	2.29e-94	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PKEHELCK_01127	7.76e-234	aroF	2.5.1.54	-	E	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	DAHP synthetase I family
PKEHELCK_01128	2.25e-209	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PKEHELCK_01129	0.0	tkt2	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PKEHELCK_01130	1.35e-261	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
PKEHELCK_01131	1.49e-146	-	-	-	S	-	-	-	Membrane
PKEHELCK_01132	3.73e-53	-	-	-	S	-	-	-	Membrane
PKEHELCK_01133	4.92e-209	yitS	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
PKEHELCK_01134	8.98e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
PKEHELCK_01135	4.58e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PKEHELCK_01136	3.06e-194	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PKEHELCK_01137	1.38e-183	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PKEHELCK_01138	2.01e-211	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PKEHELCK_01139	1.98e-197	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PKEHELCK_01140	1.07e-264	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PKEHELCK_01141	3.19e-194	-	-	-	S	-	-	-	FMN_bind
PKEHELCK_01142	0.0	ndh	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
PKEHELCK_01143	5.37e-112	-	-	-	S	-	-	-	NusG domain II
PKEHELCK_01144	1.41e-122	hepA	2.5.1.30	-	S	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase component I
PKEHELCK_01145	1.02e-233	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
PKEHELCK_01146	7.76e-81	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
PKEHELCK_01147	2.19e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PKEHELCK_01148	7.71e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PKEHELCK_01149	9.65e-79	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PKEHELCK_01150	9.87e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PKEHELCK_01151	1.84e-160	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PKEHELCK_01152	5.95e-300	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PKEHELCK_01153	1.32e-91	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
PKEHELCK_01154	8.44e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
PKEHELCK_01155	5.32e-109	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PKEHELCK_01156	1.75e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PKEHELCK_01157	2.14e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PKEHELCK_01158	4.99e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PKEHELCK_01159	3.53e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PKEHELCK_01160	4.1e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PKEHELCK_01161	2.98e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PKEHELCK_01162	1.96e-54	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PKEHELCK_01163	1.11e-33	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
PKEHELCK_01164	8.29e-100	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PKEHELCK_01165	5.46e-152	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PKEHELCK_01166	3.59e-69	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PKEHELCK_01167	1.85e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PKEHELCK_01168	6.61e-193	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PKEHELCK_01169	2.27e-59	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PKEHELCK_01170	9.83e-141	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
PKEHELCK_01171	4.34e-145	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PKEHELCK_01172	4.46e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
PKEHELCK_01173	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PKEHELCK_01174	1.19e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PKEHELCK_01175	4.19e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PKEHELCK_01176	1.81e-150	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
PKEHELCK_01177	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PKEHELCK_01178	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PKEHELCK_01179	1.16e-140	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PKEHELCK_01180	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
PKEHELCK_01181	9.78e-102	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
PKEHELCK_01189	1.62e-294	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PKEHELCK_01190	1.11e-148	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
PKEHELCK_01191	1.29e-153	dacB	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
PKEHELCK_01192	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
PKEHELCK_01193	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
PKEHELCK_01194	1.7e-118	-	-	-	K	-	-	-	Transcriptional regulator
PKEHELCK_01195	7.14e-128	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
PKEHELCK_01196	3.88e-198	-	-	-	I	-	-	-	alpha/beta hydrolase fold
PKEHELCK_01197	4.15e-153	-	-	-	I	-	-	-	phosphatase
PKEHELCK_01198	2.34e-242	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
PKEHELCK_01199	7.76e-100	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
PKEHELCK_01200	2.66e-168	-	-	-	S	-	-	-	Putative threonine/serine exporter
PKEHELCK_01201	1.78e-42	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
PKEHELCK_01202	2.94e-155	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
PKEHELCK_01203	1.36e-77	-	-	-	-	-	-	-	-
PKEHELCK_01204	7.79e-112	-	-	-	K	-	-	-	MerR HTH family regulatory protein
PKEHELCK_01205	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
PKEHELCK_01206	7.8e-152	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
PKEHELCK_01207	1.46e-170	-	-	-	-	-	-	-	-
PKEHELCK_01208	1.75e-47	-	-	-	K	-	-	-	MerR HTH family regulatory protein
PKEHELCK_01209	1.43e-155	azlC	-	-	E	-	-	-	branched-chain amino acid
PKEHELCK_01210	2.41e-66	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
PKEHELCK_01211	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
PKEHELCK_01212	1.2e-281	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
PKEHELCK_01213	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PKEHELCK_01214	0.0	xylP2	-	-	G	-	-	-	symporter
PKEHELCK_01215	7.32e-247	-	-	-	I	-	-	-	alpha/beta hydrolase fold
PKEHELCK_01216	2.74e-63	-	-	-	-	-	-	-	-
PKEHELCK_01217	1.91e-272	gudD	4.2.1.40	-	M	ko:K01706	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain
PKEHELCK_01218	4.58e-90	-	-	-	K	-	-	-	LysR substrate binding domain
PKEHELCK_01219	4.77e-161	-	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
PKEHELCK_01220	1.21e-214	yflS	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
PKEHELCK_01221	5.42e-149	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
PKEHELCK_01222	2.41e-152	-	-	-	N	-	-	-	WxL domain surface cell wall-binding
PKEHELCK_01223	1.97e-200	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
PKEHELCK_01224	0.0	-	-	-	N	-	-	-	domain, Protein
PKEHELCK_01225	2.41e-157	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
PKEHELCK_01226	1.02e-155	-	-	-	S	-	-	-	repeat protein
PKEHELCK_01227	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
PKEHELCK_01228	2.18e-219	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PKEHELCK_01229	2.62e-168	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
PKEHELCK_01230	2.16e-39	-	-	-	-	-	-	-	-
PKEHELCK_01231	3.45e-240	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
PKEHELCK_01232	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PKEHELCK_01233	4.86e-45	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
PKEHELCK_01234	6.45e-111	-	-	-	-	-	-	-	-
PKEHELCK_01235	3.95e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PKEHELCK_01236	1.21e-268	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
PKEHELCK_01237	8.65e-228	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
PKEHELCK_01238	2.36e-285	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PKEHELCK_01239	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
PKEHELCK_01240	2.15e-209	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	L-malate dehydrogenase activity
PKEHELCK_01241	2.64e-62	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
PKEHELCK_01242	2.48e-177	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
PKEHELCK_01243	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
PKEHELCK_01244	6.34e-257	-	-	-	-	-	-	-	-
PKEHELCK_01245	9.51e-135	-	-	-	-	-	-	-	-
PKEHELCK_01246	0.0	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
PKEHELCK_01247	1.73e-284	-	-	-	-	-	-	-	-
PKEHELCK_01248	6.04e-51	-	-	-	-	-	-	-	-
PKEHELCK_01249	2.51e-261	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
PKEHELCK_01250	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
PKEHELCK_01251	1.91e-66	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
PKEHELCK_01252	7.08e-131	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
PKEHELCK_01253	2.56e-110	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PKEHELCK_01254	3.01e-251	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
PKEHELCK_01255	2.19e-163	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
PKEHELCK_01256	4.11e-115	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
PKEHELCK_01257	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
PKEHELCK_01258	2.07e-240	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
PKEHELCK_01259	1.18e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
PKEHELCK_01260	2.9e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PKEHELCK_01261	1.05e-259	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
PKEHELCK_01262	1.29e-200	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PKEHELCK_01263	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PKEHELCK_01264	5.89e-204	-	-	-	S	-	-	-	Tetratricopeptide repeat
PKEHELCK_01265	4.38e-286	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PKEHELCK_01266	3.21e-288	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PKEHELCK_01267	7.8e-300	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PKEHELCK_01268	9.6e-143	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
PKEHELCK_01269	1.3e-65	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
PKEHELCK_01270	3.75e-94	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
PKEHELCK_01271	5.12e-31	-	-	-	-	-	-	-	-
PKEHELCK_01272	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
PKEHELCK_01273	3.97e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PKEHELCK_01274	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PKEHELCK_01275	8.45e-162	epsB	-	-	M	-	-	-	biosynthesis protein
PKEHELCK_01276	2.02e-156	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
PKEHELCK_01277	5.54e-189	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
PKEHELCK_01278	2.05e-229	cps4D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
PKEHELCK_01279	3.47e-69	tuaA	-	-	M	-	-	-	Bacterial sugar transferase
PKEHELCK_01280	2.78e-84	tuaA	-	-	M	-	-	-	Bacterial sugar transferase
PKEHELCK_01281	1.15e-258	cps4F	-	-	M	-	-	-	Glycosyl transferases group 1
PKEHELCK_01282	2.26e-243	cps4G	-	-	M	-	-	-	Glycosyltransferase Family 4
PKEHELCK_01283	1.91e-297	-	-	-	-	-	-	-	-
PKEHELCK_01284	3.4e-228	cps4I	-	-	M	-	-	-	Glycosyltransferase like family 2
PKEHELCK_01285	0.0	cps4J	-	-	S	-	-	-	MatE
PKEHELCK_01286	0.0	-	3.1.4.53	-	S	ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
PKEHELCK_01287	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
PKEHELCK_01288	4.24e-218	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
PKEHELCK_01289	3.02e-175	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
PKEHELCK_01290	1.55e-311	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PKEHELCK_01291	6.62e-62	-	-	-	-	-	-	-	-
PKEHELCK_01292	8.34e-228	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
PKEHELCK_01293	7.09e-180	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
PKEHELCK_01294	1.84e-67	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
PKEHELCK_01295	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
PKEHELCK_01296	1.52e-120	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PKEHELCK_01297	3.58e-129	-	-	-	K	-	-	-	Helix-turn-helix domain
PKEHELCK_01298	6.75e-269	-	-	-	EGP	-	-	-	Major facilitator Superfamily
PKEHELCK_01299	2.84e-75	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
PKEHELCK_01300	2.58e-177	-	-	-	Q	-	-	-	Methyltransferase
PKEHELCK_01301	7.15e-43	-	-	-	-	-	-	-	-
PKEHELCK_01302	7.67e-75	-	-	-	S	-	-	-	Phage integrase family
PKEHELCK_01310	1.17e-37	-	-	-	E	-	-	-	Zn peptidase
PKEHELCK_01311	3.54e-32	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PKEHELCK_01315	1.7e-78	-	-	-	S	-	-	-	DNA binding
PKEHELCK_01322	2.19e-23	-	-	-	-	-	-	-	-
PKEHELCK_01324	4.94e-187	-	-	-	S	-	-	-	Protein of unknown function (DUF1351)
PKEHELCK_01325	4.84e-137	-	-	-	S	-	-	-	ERF superfamily
PKEHELCK_01326	4.14e-93	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PKEHELCK_01327	6.41e-171	-	-	-	S	-	-	-	Putative HNHc nuclease
PKEHELCK_01328	4.12e-14	-	-	-	S	-	-	-	HNH endonuclease
PKEHELCK_01329	2.2e-40	-	-	-	L	-	-	-	Conserved phage C-terminus (Phg_2220_C)
PKEHELCK_01330	3.41e-186	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
PKEHELCK_01332	0.0	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
PKEHELCK_01333	2.74e-112	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
PKEHELCK_01334	2.08e-213	drrA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
PKEHELCK_01335	5.09e-165	drrB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
PKEHELCK_01336	1.75e-295	-	-	-	M	-	-	-	O-Antigen ligase
PKEHELCK_01337	6.85e-164	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
PKEHELCK_01338	5.16e-248	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PKEHELCK_01339	3.17e-299	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
PKEHELCK_01340	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
PKEHELCK_01342	1.66e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
PKEHELCK_01343	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
PKEHELCK_01344	8.69e-230	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
PKEHELCK_01345	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
PKEHELCK_01346	2.51e-98	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
PKEHELCK_01347	7.94e-218	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
PKEHELCK_01348	3.13e-211	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
PKEHELCK_01349	3.99e-92	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PKEHELCK_01350	7.1e-176	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PKEHELCK_01351	1.3e-132	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PKEHELCK_01352	2.69e-167	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
PKEHELCK_01353	2.24e-126	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PKEHELCK_01354	1.72e-245	-	-	-	S	-	-	-	Helix-turn-helix domain
PKEHELCK_01355	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
PKEHELCK_01356	1.25e-39	-	-	-	M	-	-	-	Lysin motif
PKEHELCK_01357	1.27e-151	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
PKEHELCK_01358	1.98e-281	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
PKEHELCK_01359	4.84e-313	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
PKEHELCK_01360	5.57e-55	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PKEHELCK_01361	7.1e-292	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
PKEHELCK_01362	3.05e-191	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
PKEHELCK_01363	1.39e-185	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PKEHELCK_01364	1.27e-291	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
PKEHELCK_01365	6.46e-109	-	-	-	-	-	-	-	-
PKEHELCK_01366	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
PKEHELCK_01367	4.04e-242	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PKEHELCK_01368	1.8e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PKEHELCK_01369	2.03e-189	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
PKEHELCK_01370	5.66e-207	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
PKEHELCK_01371	3.29e-147	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
PKEHELCK_01372	9.33e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
PKEHELCK_01373	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
PKEHELCK_01374	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
PKEHELCK_01375	4.28e-253	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
PKEHELCK_01376	3.53e-160	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
PKEHELCK_01377	8.65e-104	-	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
PKEHELCK_01378	3.52e-84	-	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
PKEHELCK_01379	7.05e-219	cpsY	-	-	K	-	-	-	Transcriptional regulator, LysR family
PKEHELCK_01380	5.13e-292	XK27_05470	-	-	E	-	-	-	Methionine synthase
PKEHELCK_01382	2.25e-207	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PKEHELCK_01383	1.01e-175	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PKEHELCK_01384	8.11e-203	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
PKEHELCK_01385	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PKEHELCK_01386	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
PKEHELCK_01387	1.5e-227	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
PKEHELCK_01388	6.84e-121	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
PKEHELCK_01389	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PKEHELCK_01390	5.16e-217	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
PKEHELCK_01391	2.4e-137	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PKEHELCK_01392	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PKEHELCK_01393	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PKEHELCK_01394	3.82e-228	-	-	-	K	-	-	-	Transcriptional regulator
PKEHELCK_01395	3.21e-215	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
PKEHELCK_01396	1.27e-103	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
PKEHELCK_01397	9.17e-126	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PKEHELCK_01398	1.07e-43	-	-	-	S	-	-	-	YozE SAM-like fold
PKEHELCK_01399	4.19e-203	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
PKEHELCK_01400	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PKEHELCK_01401	1.13e-308	-	-	-	M	-	-	-	Glycosyl transferase family group 2
PKEHELCK_01402	3.22e-87	-	-	-	-	-	-	-	-
PKEHELCK_01403	1.89e-94	gshR1	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
PKEHELCK_01404	9.07e-213	gshR1	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
PKEHELCK_01405	1.48e-98	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
PKEHELCK_01406	3.29e-121	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
PKEHELCK_01407	0.0	tarL	2.7.8.14, 2.7.8.47	-	H	ko:K18704	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
PKEHELCK_01408	2.77e-271	tarK	2.7.8.14, 2.7.8.46, 2.7.8.47	-	H	ko:K18704,ko:K21592	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
PKEHELCK_01409	2.18e-245	tarJ	1.1.1.137, 1.1.1.405	-	E	ko:K05352,ko:K21680	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
PKEHELCK_01410	2.13e-151	tarI	2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21030	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
PKEHELCK_01411	8.23e-291	-	-	-	-	-	-	-	-
PKEHELCK_01412	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
PKEHELCK_01413	7.79e-78	-	-	-	-	-	-	-	-
PKEHELCK_01414	2.79e-181	-	-	-	-	-	-	-	-
PKEHELCK_01415	7.45e-313	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
PKEHELCK_01416	1.05e-176	XK27_00890	-	-	S	ko:K08974	-	ko00000	Domain of unknown function (DUF368)
PKEHELCK_01417	9.3e-167	yejC	-	-	S	-	-	-	Protein of unknown function (DUF1003)
PKEHELCK_01418	1.33e-67	XK27_08430	-	-	S	-	-	-	Staphylococcal protein of unknown function (DUF960)
PKEHELCK_01420	1.45e-102	uspA3	-	-	T	-	-	-	universal stress protein
PKEHELCK_01421	5.88e-202	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
PKEHELCK_01422	3.77e-24	-	-	-	-	-	-	-	-
PKEHELCK_01423	1.09e-55	-	-	-	S	-	-	-	zinc-ribbon domain
PKEHELCK_01424	2.12e-98	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
PKEHELCK_01425	4.05e-64	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
PKEHELCK_01426	1.38e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
PKEHELCK_01427	5.31e-285	-	-	-	M	-	-	-	Glycosyl transferases group 1
PKEHELCK_01428	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
PKEHELCK_01429	2.74e-207	-	-	-	S	-	-	-	Putative esterase
PKEHELCK_01430	3.53e-169	-	-	-	K	-	-	-	Transcriptional regulator
PKEHELCK_01431	6.74e-117	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PKEHELCK_01432	2.13e-116	-	-	-	-	-	-	-	-
PKEHELCK_01433	8.08e-45	-	-	-	-	-	-	-	-
PKEHELCK_01434	4.85e-151	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
PKEHELCK_01435	8.05e-179	rrp8	-	-	K	-	-	-	LytTr DNA-binding domain
PKEHELCK_01436	1.7e-118	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
PKEHELCK_01437	1.55e-79	-	-	-	-	-	-	-	-
PKEHELCK_01438	2.61e-96	hsp2	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
PKEHELCK_01439	2.97e-76	-	-	-	-	-	-	-	-
PKEHELCK_01440	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
PKEHELCK_01441	1.18e-114	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
PKEHELCK_01442	0.0	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
PKEHELCK_01443	2.03e-271	yttB	-	-	EGP	-	-	-	Major Facilitator
PKEHELCK_01444	2.73e-80	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
PKEHELCK_01445	2.1e-218	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
PKEHELCK_01446	4.71e-74	-	-	-	S	-	-	-	SdpI/YhfL protein family
PKEHELCK_01447	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PKEHELCK_01448	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	Bacterial regulatory proteins, gntR family
PKEHELCK_01449	2.39e-276	araT2	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
PKEHELCK_01450	1.21e-183	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PKEHELCK_01451	3.59e-26	-	-	-	-	-	-	-	-
PKEHELCK_01452	2.09e-169	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
PKEHELCK_01453	9.49e-207	mleR	-	-	K	-	-	-	LysR family
PKEHELCK_01454	5.26e-148	-	-	-	GM	-	-	-	NAD(P)H-binding
PKEHELCK_01455	3.86e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
PKEHELCK_01456	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
PKEHELCK_01457	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
PKEHELCK_01458	9.44e-219	oroP	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
PKEHELCK_01459	6.64e-146	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PKEHELCK_01460	1.55e-161	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
PKEHELCK_01461	1.04e-218	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PKEHELCK_01462	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
PKEHELCK_01463	3.36e-272	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
PKEHELCK_01464	2.38e-310	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PKEHELCK_01465	1.22e-220	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
PKEHELCK_01466	7.13e-123	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PKEHELCK_01467	0.0	pucR_2	-	-	QT	ko:K09684	-	ko00000,ko03000	Purine catabolism regulatory protein-like family
PKEHELCK_01468	3.1e-305	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
PKEHELCK_01469	5.67e-280	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
PKEHELCK_01470	1.29e-205	-	-	-	GM	-	-	-	NmrA-like family
PKEHELCK_01471	1.25e-199	-	-	-	T	-	-	-	EAL domain
PKEHELCK_01472	2.62e-121	-	-	-	-	-	-	-	-
PKEHELCK_01473	0.0	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
PKEHELCK_01474	4.17e-163	-	-	-	E	-	-	-	Methionine synthase
PKEHELCK_01475	9.06e-279	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
PKEHELCK_01476	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
PKEHELCK_01477	5.35e-133	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PKEHELCK_01478	2.97e-243	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
PKEHELCK_01479	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PKEHELCK_01480	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PKEHELCK_01481	1.63e-162	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PKEHELCK_01482	1.17e-55	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PKEHELCK_01483	9.7e-168	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
PKEHELCK_01484	4.08e-270	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PKEHELCK_01485	3.77e-104	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PKEHELCK_01486	7.9e-305	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
PKEHELCK_01487	9.92e-143	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
PKEHELCK_01488	8.18e-243	lplL	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Bacterial lipoate protein ligase C-terminus
PKEHELCK_01489	2.04e-189	ptp3	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
PKEHELCK_01490	3.44e-152	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
PKEHELCK_01491	4.15e-191	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
PKEHELCK_01492	3.7e-233	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
PKEHELCK_01493	2.05e-178	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PKEHELCK_01494	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
PKEHELCK_01495	4.76e-56	-	-	-	-	-	-	-	-
PKEHELCK_01496	8.2e-81	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
PKEHELCK_01497	7.89e-212	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PKEHELCK_01498	3.41e-190	-	-	-	-	-	-	-	-
PKEHELCK_01499	2.7e-104	usp5	-	-	T	-	-	-	universal stress protein
PKEHELCK_01500	1.08e-47	-	-	-	-	-	-	-	-
PKEHELCK_01501	4.02e-95	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
PKEHELCK_01502	1.76e-114	-	-	-	-	-	-	-	-
PKEHELCK_01503	4.87e-66	-	-	-	-	-	-	-	-
PKEHELCK_01504	4.79e-13	-	-	-	-	-	-	-	-
PKEHELCK_01505	8.32e-297	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
PKEHELCK_01506	1.16e-110	-	-	-	F	-	-	-	belongs to the nudix hydrolase family
PKEHELCK_01507	4.34e-151	-	-	-	-	-	-	-	-
PKEHELCK_01508	1.21e-69	-	-	-	-	-	-	-	-
PKEHELCK_01510	8.02e-110	-	-	-	S	-	-	-	Pfam:DUF3816
PKEHELCK_01511	3.47e-306	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PKEHELCK_01512	1.27e-143	-	-	-	-	-	-	-	-
PKEHELCK_01513	1.08e-229	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
PKEHELCK_01514	1.57e-184	-	-	-	S	-	-	-	Peptidase_C39 like family
PKEHELCK_01515	1.04e-120	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
PKEHELCK_01516	1.95e-149	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
PKEHELCK_01517	3.82e-188	-	-	-	KT	-	-	-	helix_turn_helix, mercury resistance
PKEHELCK_01518	3.41e-295	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PKEHELCK_01519	3.09e-122	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
PKEHELCK_01520	4.88e-240	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
PKEHELCK_01521	7.14e-157	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PKEHELCK_01522	2.27e-116	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
PKEHELCK_01523	8.13e-238	iunH3	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
PKEHELCK_01524	1.45e-126	ywjB	-	-	H	-	-	-	RibD C-terminal domain
PKEHELCK_01525	8.02e-258	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
PKEHELCK_01526	9.01e-155	-	-	-	S	-	-	-	Membrane
PKEHELCK_01527	3.49e-198	mleP3	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
PKEHELCK_01528	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
PKEHELCK_01529	1.18e-257	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
PKEHELCK_01530	1.99e-160	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
PKEHELCK_01531	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
PKEHELCK_01532	2.33e-103	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
PKEHELCK_01533	7.96e-127	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
PKEHELCK_01534	4.38e-222	-	-	-	S	-	-	-	Conserved hypothetical protein 698
PKEHELCK_01535	2.06e-194	rlrG	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
PKEHELCK_01536	0.0	tagE5	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
PKEHELCK_01537	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
PKEHELCK_01539	9.92e-88	-	-	-	M	-	-	-	LysM domain
PKEHELCK_01540	9.24e-119	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
PKEHELCK_01541	1.65e-212	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PKEHELCK_01542	6.76e-270	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
PKEHELCK_01543	6.27e-166	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
PKEHELCK_01544	9.52e-72	cmd	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
PKEHELCK_01545	4.77e-100	yphH	-	-	S	-	-	-	Cupin domain
PKEHELCK_01546	1.52e-87	-	-	-	K	-	-	-	transcriptional regulator, MerR family
PKEHELCK_01547	2.94e-299	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
PKEHELCK_01548	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
PKEHELCK_01549	1.74e-156	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PKEHELCK_01551	2.93e-151	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PKEHELCK_01552	3.18e-141	thgA3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
PKEHELCK_01553	1.03e-150	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
PKEHELCK_01555	4.86e-111	-	-	-	-	-	-	-	-
PKEHELCK_01556	2.07e-64	yvbK	-	-	K	-	-	-	GNAT family
PKEHELCK_01557	1.1e-37	yvbK	-	-	K	-	-	-	GNAT family
PKEHELCK_01558	9.76e-50	-	-	-	-	-	-	-	-
PKEHELCK_01559	2.81e-64	-	-	-	-	-	-	-	-
PKEHELCK_01560	7.44e-143	pgm8	-	-	G	-	-	-	Histidine phosphatase superfamily (branch 1)
PKEHELCK_01561	6.09e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
PKEHELCK_01562	1.51e-200	-	-	-	K	-	-	-	LysR substrate binding domain
PKEHELCK_01563	1.78e-134	-	-	-	GM	-	-	-	NAD(P)H-binding
PKEHELCK_01564	1.66e-247	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
PKEHELCK_01565	2.9e-194	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
PKEHELCK_01566	1.28e-45	-	-	-	-	-	-	-	-
PKEHELCK_01567	2.1e-99	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
PKEHELCK_01568	2.09e-124	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
PKEHELCK_01569	1.02e-161	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
PKEHELCK_01570	2.31e-79	-	-	-	-	-	-	-	-
PKEHELCK_01571	5.29e-131	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
PKEHELCK_01572	2.33e-283	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
PKEHELCK_01573	1.07e-131	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
PKEHELCK_01574	1.8e-249	-	-	-	C	-	-	-	Aldo/keto reductase family
PKEHELCK_01576	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PKEHELCK_01577	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PKEHELCK_01578	6.27e-316	-	-	-	EGP	-	-	-	Major Facilitator
PKEHELCK_01582	2.06e-314	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
PKEHELCK_01583	3.01e-124	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
PKEHELCK_01584	6.88e-71	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
PKEHELCK_01585	4.19e-197	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
PKEHELCK_01586	1.34e-132	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
PKEHELCK_01587	1.24e-125	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
PKEHELCK_01588	3.27e-171	-	-	-	M	-	-	-	Phosphotransferase enzyme family
PKEHELCK_01589	3.18e-282	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
PKEHELCK_01590	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
PKEHELCK_01591	1.9e-189	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
PKEHELCK_01592	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
PKEHELCK_01593	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC
PKEHELCK_01595	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
PKEHELCK_01596	3.69e-230	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
PKEHELCK_01597	1.46e-211	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
PKEHELCK_01598	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
PKEHELCK_01599	1.11e-143	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
PKEHELCK_01600	6.88e-226	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
PKEHELCK_01601	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
PKEHELCK_01602	2.07e-161	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
PKEHELCK_01603	1.35e-165	pgm3	-	-	G	-	-	-	Phosphoglycerate mutase family
PKEHELCK_01604	1.61e-36	-	-	-	-	-	-	-	-
PKEHELCK_01605	2.27e-53	sugE	-	-	U	ko:K11741	-	ko00000,ko02000	Multidrug resistance protein
PKEHELCK_01606	3.79e-101	rppH3	-	-	F	-	-	-	NUDIX domain
PKEHELCK_01607	5.95e-300	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PKEHELCK_01608	1.81e-128	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PKEHELCK_01609	2.93e-109	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
PKEHELCK_01610	9.18e-195	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
PKEHELCK_01611	7.75e-61	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
PKEHELCK_01612	8.83e-93	-	-	-	K	-	-	-	MarR family
PKEHELCK_01613	8.87e-191	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
PKEHELCK_01614	6.26e-96	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
PKEHELCK_01615	1.15e-72	steT	-	-	E	ko:K03294	-	ko00000	amino acid
PKEHELCK_01616	2.84e-208	steT	-	-	E	ko:K03294	-	ko00000	amino acid
PKEHELCK_01617	4.87e-180	-	3.5.1.105	-	G	ko:K03478	-	ko00000,ko01000	YdjC-like protein
PKEHELCK_01618	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
PKEHELCK_01619	7.77e-197	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
PKEHELCK_01620	7.04e-108	-	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
PKEHELCK_01621	1.27e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PKEHELCK_01622	3.14e-140	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PKEHELCK_01623	3.39e-190	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
PKEHELCK_01624	2.3e-172	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PKEHELCK_01626	1.28e-54	-	-	-	-	-	-	-	-
PKEHELCK_01627	1.03e-217	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PKEHELCK_01628	3.21e-268	aspC	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
PKEHELCK_01629	6.94e-146	gph1	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD hydrolase, family IA, variant
PKEHELCK_01630	1.01e-188	-	-	-	-	-	-	-	-
PKEHELCK_01631	5.27e-16	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
PKEHELCK_01632	2.02e-106	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
PKEHELCK_01633	2.45e-134	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
PKEHELCK_01634	1.48e-27	-	-	-	-	-	-	-	-
PKEHELCK_01635	7.48e-96	-	-	-	F	-	-	-	Nudix hydrolase
PKEHELCK_01636	1.23e-189	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
PKEHELCK_01637	6.12e-115	-	-	-	-	-	-	-	-
PKEHELCK_01638	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
PKEHELCK_01639	3.8e-61	-	-	-	-	-	-	-	-
PKEHELCK_01640	1.55e-89	-	-	-	O	-	-	-	OsmC-like protein
PKEHELCK_01641	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
PKEHELCK_01642	0.0	oatA	-	-	I	-	-	-	Acyltransferase
PKEHELCK_01643	5.01e-229	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PKEHELCK_01644	3.45e-231	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
PKEHELCK_01645	0.0	pox2	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
PKEHELCK_01646	5.47e-198	ribC1	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
PKEHELCK_01647	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
PKEHELCK_01648	1.79e-287	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
PKEHELCK_01649	5.55e-27	-	-	-	-	-	-	-	-
PKEHELCK_01650	6.16e-107	-	-	-	K	-	-	-	Transcriptional regulator
PKEHELCK_01651	9.11e-195	licD	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
PKEHELCK_01652	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
PKEHELCK_01653	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PKEHELCK_01654	4.45e-226	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
PKEHELCK_01655	4.16e-313	-	-	-	EGP	-	-	-	Major Facilitator
PKEHELCK_01656	1.71e-116	-	-	-	V	-	-	-	VanZ like family
PKEHELCK_01657	3.88e-46	-	-	-	-	-	-	-	-
PKEHELCK_01658	5.45e-94	spx1	-	-	P	ko:K16509	-	ko00000	ArsC family
PKEHELCK_01660	1.62e-149	-	-	-	-	-	-	-	-
PKEHELCK_01661	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PKEHELCK_01662	3.06e-178	-	-	-	EGP	-	-	-	Transmembrane secretion effector
PKEHELCK_01663	2.87e-168	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
PKEHELCK_01664	2.49e-95	-	-	-	-	-	-	-	-
PKEHELCK_01665	2.79e-69	-	-	-	-	-	-	-	-
PKEHELCK_01666	2.41e-262	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
PKEHELCK_01667	6.62e-129	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PKEHELCK_01668	8.04e-190	-	3.1.3.23	-	S	ko:K07757	-	ko00000,ko01000	Sucrose-6F-phosphate phosphohydrolase
PKEHELCK_01669	5.44e-159	-	-	-	T	-	-	-	EAL domain
PKEHELCK_01670	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PKEHELCK_01671	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PKEHELCK_01672	2.18e-182	ybbR	-	-	S	-	-	-	YbbR-like protein
PKEHELCK_01673	2.39e-191	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PKEHELCK_01674	1.64e-87	-	-	-	-	-	-	-	-
PKEHELCK_01675	0.0	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
PKEHELCK_01676	1.96e-73	-	-	-	-	-	-	-	-
PKEHELCK_01677	3.74e-284	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PKEHELCK_01678	2.65e-102	-	-	-	S	ko:K02348	-	ko00000	GNAT family
PKEHELCK_01679	1.24e-99	-	-	-	K	-	-	-	Transcriptional regulator
PKEHELCK_01680	9.59e-288	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
PKEHELCK_01681	2.18e-53	-	-	-	-	-	-	-	-
PKEHELCK_01682	3.07e-264	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PKEHELCK_01683	1.31e-179	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PKEHELCK_01684	3.14e-190	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PKEHELCK_01685	1.46e-262	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
PKEHELCK_01686	3.68e-125	-	-	-	K	-	-	-	Cupin domain
PKEHELCK_01687	8.08e-110	-	-	-	S	-	-	-	ASCH
PKEHELCK_01688	1.88e-111	-	-	-	K	-	-	-	GNAT family
PKEHELCK_01689	1.02e-115	-	-	-	K	-	-	-	acetyltransferase
PKEHELCK_01690	2.06e-30	-	-	-	-	-	-	-	-
PKEHELCK_01691	5.05e-79	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
PKEHELCK_01692	5.86e-239	-	-	-	-	-	-	-	-
PKEHELCK_01693	0.0	acdH	1.1.1.1, 1.2.1.10, 1.2.1.87	-	C	ko:K04072,ko:K13922	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
PKEHELCK_01694	8.16e-207	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
PKEHELCK_01696	2.36e-305	xylP1	-	-	G	-	-	-	MFS/sugar transport protein
PKEHELCK_01697	1.43e-170	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
PKEHELCK_01698	3.45e-34	-	-	-	-	-	-	-	-
PKEHELCK_01699	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
PKEHELCK_01700	6.4e-54	-	-	-	-	-	-	-	-
PKEHELCK_01701	1.54e-123	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
PKEHELCK_01702	2.37e-224	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PKEHELCK_01703	4.03e-81	-	-	-	S	-	-	-	CHY zinc finger
PKEHELCK_01704	3.07e-113	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
PKEHELCK_01705	1.25e-155	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
PKEHELCK_01706	1.1e-280	-	-	-	-	-	-	-	-
PKEHELCK_01707	4.7e-198	tagG	-	-	U	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
PKEHELCK_01708	9.42e-258	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
PKEHELCK_01709	6.53e-58	-	-	-	-	-	-	-	-
PKEHELCK_01710	4.63e-119	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
PKEHELCK_01711	0.0	-	-	-	P	-	-	-	Major Facilitator Superfamily
PKEHELCK_01712	1.66e-305	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
PKEHELCK_01713	7.39e-226	hicD1	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
PKEHELCK_01714	8.95e-60	-	-	-	-	-	-	-	-
PKEHELCK_01715	1.05e-132	zmp1	-	-	O	-	-	-	Zinc-dependent metalloprotease
PKEHELCK_01716	6.87e-153	rpiA2	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
PKEHELCK_01717	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
PKEHELCK_01718	5.34e-72	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
PKEHELCK_01719	5.33e-124	yxkA	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
PKEHELCK_01720	1.96e-295	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
PKEHELCK_01721	5.89e-108	-	-	-	K	-	-	-	Winged helix-turn-helix transcription repressor, HrcA DNA-binding
PKEHELCK_01722	2.16e-103	-	-	-	-	-	-	-	-
PKEHELCK_01723	3.45e-103	accB3	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PKEHELCK_01724	1.49e-223	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
PKEHELCK_01725	2.42e-207	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
PKEHELCK_01726	4.06e-102	-	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA-DNA hybrid ribonuclease activity
PKEHELCK_01727	0.0	proWX	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
PKEHELCK_01728	1.1e-229	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
PKEHELCK_01729	0.0	gshR	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
PKEHELCK_01730	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PKEHELCK_01731	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
PKEHELCK_01732	2.14e-174	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
PKEHELCK_01733	0.0	-	-	-	M	-	-	-	domain protein
PKEHELCK_01734	2.67e-89	-	-	-	M	-	-	-	dTDP-4-dehydrorhamnose reductase activity
PKEHELCK_01735	1.82e-34	-	-	-	S	-	-	-	Immunity protein 74
PKEHELCK_01736	5.01e-226	-	-	-	-	-	-	-	-
PKEHELCK_01737	1.24e-11	-	-	-	S	-	-	-	Immunity protein 22
PKEHELCK_01738	5.89e-131	-	-	-	S	-	-	-	ankyrin repeats
PKEHELCK_01739	1.3e-49	-	-	-	-	-	-	-	-
PKEHELCK_01740	8.53e-28	-	-	-	-	-	-	-	-
PKEHELCK_01741	5.52e-64	-	-	-	U	-	-	-	nuclease activity
PKEHELCK_01742	2.05e-90	-	-	-	-	-	-	-	-
PKEHELCK_01743	1.32e-29	-	-	-	-	-	-	-	-
PKEHELCK_01745	1.44e-22	-	-	-	-	-	-	-	-
PKEHELCK_01746	3.27e-81	-	-	-	-	-	-	-	-
PKEHELCK_01748	4.56e-154	lacA	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
PKEHELCK_01749	1.84e-261	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
PKEHELCK_01750	3.41e-187	-	3.1.3.102, 3.1.3.104, 3.1.3.23	-	G	ko:K07757,ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
PKEHELCK_01751	3.91e-211	-	-	-	K	-	-	-	Transcriptional regulator
PKEHELCK_01752	8.38e-192	-	-	-	S	-	-	-	hydrolase
PKEHELCK_01753	6.17e-197	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
PKEHELCK_01754	4.66e-112	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
PKEHELCK_01755	1.78e-264	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
PKEHELCK_01757	2.2e-149	-	-	-	-	-	-	-	-
PKEHELCK_01760	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
PKEHELCK_01761	1.5e-194	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
PKEHELCK_01765	5.21e-65	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
PKEHELCK_01766	1.38e-71	-	-	-	S	-	-	-	Cupin domain
PKEHELCK_01767	1.31e-213	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
PKEHELCK_01768	1.86e-246	ysdE	-	-	P	-	-	-	Citrate transporter
PKEHELCK_01769	1.06e-195	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
PKEHELCK_01770	1.26e-173	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PKEHELCK_01771	2.4e-279	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
PKEHELCK_01772	5.41e-160	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
PKEHELCK_01773	3.99e-177	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
PKEHELCK_01774	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PKEHELCK_01775	5.27e-197	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
PKEHELCK_01776	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
PKEHELCK_01777	6.3e-95	-	-	-	-	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	-
PKEHELCK_01778	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
PKEHELCK_01779	2.91e-106	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
PKEHELCK_01780	1.71e-302	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
PKEHELCK_01781	8.77e-204	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
PKEHELCK_01783	5.68e-154	-	-	-	G	-	-	-	Peptidase_C39 like family
PKEHELCK_01784	2.63e-217	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
PKEHELCK_01785	2.43e-174	manM	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
PKEHELCK_01786	8.89e-218	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
PKEHELCK_01787	9.05e-85	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
PKEHELCK_01788	0.0	levR	-	-	K	-	-	-	Sigma-54 interaction domain
PKEHELCK_01789	1.45e-93	levD	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11194	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
PKEHELCK_01790	4.5e-113	manX	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
PKEHELCK_01791	3.15e-229	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PKEHELCK_01792	9.24e-85	accB1	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin-requiring enzyme
PKEHELCK_01793	6.9e-315	accC1	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase C-terminal domain
PKEHELCK_01794	3.66e-184	accD1	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PKEHELCK_01795	1.23e-177	accA1	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
PKEHELCK_01796	2.29e-234	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
PKEHELCK_01797	7.53e-215	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
PKEHELCK_01798	8.57e-227	-	-	-	EG	-	-	-	EamA-like transporter family
PKEHELCK_01799	1.91e-165	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PKEHELCK_01800	7.87e-158	zmp2	-	-	O	-	-	-	Zinc-dependent metalloprotease
PKEHELCK_01801	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
PKEHELCK_01802	1.62e-158	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PKEHELCK_01803	5.96e-69	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
PKEHELCK_01804	9.43e-127	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
PKEHELCK_01805	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PKEHELCK_01806	4.91e-265	yacL	-	-	S	-	-	-	domain protein
PKEHELCK_01807	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PKEHELCK_01808	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
PKEHELCK_01809	1.35e-92	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PKEHELCK_01810	1.49e-177	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PKEHELCK_01811	3.4e-126	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
PKEHELCK_01812	1.12e-130	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Sigma-70 region 2
PKEHELCK_01813	4.55e-31	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
PKEHELCK_01814	1e-39	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
PKEHELCK_01815	1.89e-128	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
PKEHELCK_01816	2.81e-202	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
PKEHELCK_01817	9.76e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PKEHELCK_01818	2.69e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PKEHELCK_01819	3.72e-105	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PKEHELCK_01820	2.76e-74	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PKEHELCK_01821	1.01e-226	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
PKEHELCK_01822	1.78e-88	-	-	-	L	-	-	-	nuclease
PKEHELCK_01823	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PKEHELCK_01824	5.82e-141	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
PKEHELCK_01825	2.47e-253	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PKEHELCK_01826	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PKEHELCK_01827	8.42e-50	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
PKEHELCK_01828	6.7e-141	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
PKEHELCK_01829	7.57e-119	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PKEHELCK_01830	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PKEHELCK_01831	2.05e-62	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PKEHELCK_01832	6.22e-140	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PKEHELCK_01833	5.87e-51	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
PKEHELCK_01834	1.28e-152	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PKEHELCK_01835	1.39e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
PKEHELCK_01836	2.33e-239	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
PKEHELCK_01837	4.9e-76	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
PKEHELCK_01838	1.26e-211	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PKEHELCK_01839	1.84e-190	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
PKEHELCK_01840	2.86e-245	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
PKEHELCK_01841	5.29e-211	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
PKEHELCK_01842	1.3e-110	queT	-	-	S	-	-	-	QueT transporter
PKEHELCK_01843	2.63e-241	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PKEHELCK_01844	1.82e-275	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine
PKEHELCK_01845	2.36e-166	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
PKEHELCK_01846	3.39e-294	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PKEHELCK_01847	3.61e-244	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PKEHELCK_01848	2.61e-260	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
PKEHELCK_01849	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
PKEHELCK_01850	9.6e-170	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
PKEHELCK_01851	7.44e-203	-	-	-	U	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PKEHELCK_01852	1.37e-248	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	ABC transporter, substratebinding protein
PKEHELCK_01853	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
PKEHELCK_01854	2.58e-85	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
PKEHELCK_01855	2.38e-273	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PKEHELCK_01856	9.32e-81	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PKEHELCK_01857	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
PKEHELCK_01858	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PKEHELCK_01859	2.14e-188	-	-	-	-	-	-	-	-
PKEHELCK_01860	1.78e-191	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
PKEHELCK_01861	5.35e-121	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
PKEHELCK_01862	3.14e-164	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
PKEHELCK_01863	1.49e-273	-	-	-	J	-	-	-	translation release factor activity
PKEHELCK_01864	1.91e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
PKEHELCK_01865	5.14e-305	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
PKEHELCK_01866	2.08e-302	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PKEHELCK_01867	4.01e-36	-	-	-	-	-	-	-	-
PKEHELCK_01868	6.59e-170	-	-	-	S	-	-	-	YheO-like PAS domain
PKEHELCK_01869	2.31e-201	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
PKEHELCK_01870	7.51e-159	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
PKEHELCK_01871	2.28e-290	sdaC	-	-	E	ko:K03837	-	ko00000,ko02000	amino acid
PKEHELCK_01872	8.29e-312	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PKEHELCK_01873	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PKEHELCK_01874	2.96e-89	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
PKEHELCK_01875	2.87e-101	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
PKEHELCK_01876	8.6e-198	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
PKEHELCK_01877	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
PKEHELCK_01878	1.45e-191	yxeH	-	-	S	-	-	-	hydrolase
PKEHELCK_01879	8.69e-179	-	-	-	-	-	-	-	-
PKEHELCK_01880	8.08e-236	-	-	-	S	-	-	-	DUF218 domain
PKEHELCK_01881	3.26e-228	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PKEHELCK_01882	9.06e-193	bla1	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
PKEHELCK_01883	5.78e-292	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PKEHELCK_01884	1.96e-189	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
PKEHELCK_01885	5.3e-49	-	-	-	-	-	-	-	-
PKEHELCK_01886	2.95e-57	-	-	-	S	-	-	-	ankyrin repeats
PKEHELCK_01887	6.39e-169	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
PKEHELCK_01888	8.05e-166	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
PKEHELCK_01889	1.9e-230	-	-	-	S	ko:K06889	-	ko00000	Prolyl oligopeptidase family
PKEHELCK_01890	2.26e-209	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PKEHELCK_01891	6.87e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
PKEHELCK_01892	1.19e-201	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PKEHELCK_01893	1.6e-127	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PKEHELCK_01894	1.63e-187	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
PKEHELCK_01896	2.06e-105	mutR	-	-	K	ko:K20373,ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
PKEHELCK_01897	1.81e-273	-	-	-	EGP	ko:K02030	-	ko00000,ko00002,ko02000	Drug resistance transporter Bcr CflA subfamily
PKEHELCK_01898	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PKEHELCK_01899	4.64e-92	-	-	-	F	-	-	-	DNA mismatch repair protein MutT
PKEHELCK_01900	1.12e-205	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
PKEHELCK_01901	2.14e-171	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
PKEHELCK_01902	4.65e-229	-	-	-	-	-	-	-	-
PKEHELCK_01903	1.37e-290	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
PKEHELCK_01904	7.87e-214	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
PKEHELCK_01905	1.98e-242	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PKEHELCK_01906	1.6e-77	chpA	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
PKEHELCK_01907	5.9e-46	-	-	-	-	-	-	-	-
PKEHELCK_01908	1.69e-97	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
PKEHELCK_01909	9.68e-34	-	-	-	-	-	-	-	-
PKEHELCK_01910	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PKEHELCK_01912	6.91e-201	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
PKEHELCK_01913	4.48e-206	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
PKEHELCK_01914	5.04e-200	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
PKEHELCK_01915	9.78e-190	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PKEHELCK_01916	9.4e-179	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PKEHELCK_01917	1.55e-150	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
PKEHELCK_01918	2.29e-64	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	positive regulation of macromolecule biosynthetic process
PKEHELCK_01919	2.87e-71	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
PKEHELCK_01920	2.55e-225	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PKEHELCK_01921	6.26e-213	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PKEHELCK_01922	2.41e-236	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
PKEHELCK_01923	1.13e-218	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
PKEHELCK_01924	6.37e-160	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
PKEHELCK_01925	0.0	nox	-	-	C	-	-	-	NADH oxidase
PKEHELCK_01926	8.65e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PKEHELCK_01927	4.33e-105	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
PKEHELCK_01928	4.69e-15	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
PKEHELCK_01929	7.54e-99	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
PKEHELCK_01930	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
PKEHELCK_01931	5.9e-170	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
PKEHELCK_01932	0.0	nox2	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
PKEHELCK_01933	4.63e-135	aad	3.4.13.22	-	E	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
PKEHELCK_01934	5.33e-268	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
PKEHELCK_01935	9.45e-152	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
PKEHELCK_01936	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PKEHELCK_01937	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
PKEHELCK_01938	2.21e-113	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PKEHELCK_01939	7.5e-302	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
PKEHELCK_01940	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
PKEHELCK_01941	7.09e-113	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
PKEHELCK_01942	1.71e-207	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
PKEHELCK_01943	5.32e-242	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
PKEHELCK_01944	1.21e-215	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
PKEHELCK_01945	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
PKEHELCK_01946	5.18e-224	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PKEHELCK_01947	5.11e-133	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PKEHELCK_01949	1.14e-311	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	Sigma-54 factor, core binding domain
PKEHELCK_01950	5.75e-242	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
PKEHELCK_01951	2.02e-245	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PKEHELCK_01952	1.31e-285	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
PKEHELCK_01953	7.15e-179	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PKEHELCK_01954	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PKEHELCK_01955	2.83e-168	-	-	-	-	-	-	-	-
PKEHELCK_01956	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
PKEHELCK_01957	1.76e-43	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
PKEHELCK_01958	3.83e-179	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
PKEHELCK_01959	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
PKEHELCK_01960	2.4e-107	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
PKEHELCK_01961	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
PKEHELCK_01962	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
PKEHELCK_01963	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PKEHELCK_01964	9.36e-171	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PKEHELCK_01965	2.29e-136	-	-	-	-	-	-	-	-
PKEHELCK_01966	1.98e-199	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
PKEHELCK_01967	1.4e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PKEHELCK_01968	1.23e-227	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
PKEHELCK_01969	1.29e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
PKEHELCK_01970	2.52e-114	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
PKEHELCK_01971	2.41e-129	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
PKEHELCK_01972	2.53e-198	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
PKEHELCK_01973	3.09e-213	ysjB	-	-	S	ko:K03810	-	ko00000	Oxidoreductase family, NAD-binding Rossmann fold
PKEHELCK_01974	6.24e-214	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
PKEHELCK_01975	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
PKEHELCK_01976	3.07e-119	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
PKEHELCK_01977	4.23e-149	-	-	-	S	-	-	-	Protein of unknown function (DUF1361)
PKEHELCK_01978	1.44e-293	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
PKEHELCK_01979	4.82e-165	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
PKEHELCK_01980	1.81e-37	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PKEHELCK_01981	5.41e-77	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PKEHELCK_01982	2.03e-118	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PKEHELCK_01983	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PKEHELCK_01984	9.14e-213	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PKEHELCK_01985	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PKEHELCK_01986	5.95e-74	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
PKEHELCK_01987	2.94e-315	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PKEHELCK_01988	1.68e-132	-	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
PKEHELCK_01989	1.44e-230	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
PKEHELCK_01990	1.52e-57	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
PKEHELCK_01991	2.54e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
PKEHELCK_01992	2.15e-280	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
PKEHELCK_01993	3.2e-64	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
PKEHELCK_01994	2.24e-239	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PKEHELCK_01995	2.1e-151	metI	-	-	U	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PKEHELCK_01996	3.03e-191	metQ	-	-	M	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
PKEHELCK_01997	3.34e-215	hicD3	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
PKEHELCK_01998	3.26e-227	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
PKEHELCK_01999	1.03e-239	-	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
PKEHELCK_02000	3.78e-272	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
PKEHELCK_02001	0.0	glpQ3	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
PKEHELCK_02002	4.7e-207	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PKEHELCK_02003	4.68e-260	bla2	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
PKEHELCK_02004	9.64e-107	uspA	-	-	T	-	-	-	universal stress protein
PKEHELCK_02005	4.5e-51	-	-	-	-	-	-	-	-
PKEHELCK_02006	7.27e-303	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
PKEHELCK_02007	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
PKEHELCK_02008	4.54e-59	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
PKEHELCK_02009	2.6e-141	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
PKEHELCK_02010	4e-105	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
PKEHELCK_02011	4.02e-145	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
PKEHELCK_02012	2.15e-137	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PKEHELCK_02013	5.28e-105	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
PKEHELCK_02014	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
PKEHELCK_02016	2.13e-276	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
PKEHELCK_02017	7.66e-292	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PKEHELCK_02018	7.78e-300	gshF	6.3.2.2	-	H	ko:K01919,ko:K16786,ko:K16787	ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the glutamate--cysteine ligase type 1 family
PKEHELCK_02019	3.56e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PKEHELCK_02020	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PKEHELCK_02021	5.62e-316	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
PKEHELCK_02022	1.15e-150	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
PKEHELCK_02023	1.74e-211	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
PKEHELCK_02024	3.76e-184	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
PKEHELCK_02025	1.29e-112	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
PKEHELCK_02026	3.81e-150	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
PKEHELCK_02027	1.23e-187	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
PKEHELCK_02028	1.89e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
PKEHELCK_02029	3.17e-149	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PKEHELCK_02030	2.61e-199	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
PKEHELCK_02031	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
PKEHELCK_02032	5.88e-295	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
PKEHELCK_02033	0.0	ymfH	-	-	S	-	-	-	Peptidase M16
PKEHELCK_02034	4.71e-171	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
PKEHELCK_02035	1.92e-127	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PKEHELCK_02036	3.83e-295	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
PKEHELCK_02037	2.43e-264	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PKEHELCK_02038	6.57e-291	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
PKEHELCK_02039	6.18e-197	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	YmdB-like protein
PKEHELCK_02040	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PKEHELCK_02041	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PKEHELCK_02042	1.91e-44	-	-	-	C	-	-	-	Flavodoxin
PKEHELCK_02043	4.13e-66	-	-	-	GM	-	-	-	NmrA-like family
PKEHELCK_02044	2.62e-173	-	-	-	C	-	-	-	Aldo/keto reductase family
PKEHELCK_02045	3.8e-86	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
PKEHELCK_02046	2.15e-86	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
PKEHELCK_02047	1.58e-47	-	-	-	C	-	-	-	Flavodoxin
PKEHELCK_02048	1e-62	adhR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
PKEHELCK_02049	2.66e-38	-	-	-	-	-	-	-	-
PKEHELCK_02050	6.88e-151	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
PKEHELCK_02051	1.43e-57	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
PKEHELCK_02052	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
PKEHELCK_02053	5.04e-91	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
PKEHELCK_02054	7.07e-272	-	-	-	T	-	-	-	diguanylate cyclase
PKEHELCK_02055	6.68e-156	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
PKEHELCK_02056	4.03e-118	-	-	-	-	-	-	-	-
PKEHELCK_02057	1.12e-209	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
PKEHELCK_02058	1.58e-72	nudA	-	-	S	-	-	-	ASCH
PKEHELCK_02059	1.4e-138	-	-	-	S	-	-	-	SdpI/YhfL protein family
PKEHELCK_02060	1.44e-128	-	-	-	M	-	-	-	Lysin motif
PKEHELCK_02061	2.18e-99	-	-	-	M	-	-	-	LysM domain
PKEHELCK_02062	2.1e-99	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
PKEHELCK_02063	6.41e-237	-	-	-	GM	-	-	-	Male sterility protein
PKEHELCK_02064	0.0	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
PKEHELCK_02065	0.0	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PKEHELCK_02066	7.47e-70	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
PKEHELCK_02067	3.91e-100	pts23A	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
PKEHELCK_02068	2.1e-178	-	-	-	K	-	-	-	Helix-turn-helix domain
PKEHELCK_02069	1.21e-73	-	-	-	-	-	-	-	-
PKEHELCK_02070	1.93e-205	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
PKEHELCK_02071	2.03e-84	-	-	-	-	-	-	-	-
PKEHELCK_02072	0.0	-	-	-	P	-	-	-	Concanavalin A-like lectin/glucanases superfamily
PKEHELCK_02073	9.07e-236	-	-	-	P	-	-	-	Concanavalin A-like lectin/glucanases superfamily
PKEHELCK_02074	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PKEHELCK_02075	7.89e-124	-	-	-	P	-	-	-	Cadmium resistance transporter
PKEHELCK_02076	8.58e-65	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
PKEHELCK_02077	1.81e-150	-	-	-	S	-	-	-	SNARE associated Golgi protein
PKEHELCK_02078	7.03e-62	-	-	-	-	-	-	-	-
PKEHELCK_02079	1.18e-94	usp2	-	-	T	-	-	-	Belongs to the universal stress protein A family
PKEHELCK_02080	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
PKEHELCK_02081	3.35e-157	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PKEHELCK_02082	2.88e-106	gtcA3	-	-	S	-	-	-	GtrA-like protein
PKEHELCK_02083	2.81e-167	zmp3	-	-	O	-	-	-	Zinc-dependent metalloprotease
PKEHELCK_02084	1.15e-43	-	-	-	-	-	-	-	-
PKEHELCK_02086	1.04e-269	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
PKEHELCK_02087	5.63e-196	livH	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
PKEHELCK_02088	1.88e-192	livM	-	-	E	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
PKEHELCK_02089	2.12e-179	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
PKEHELCK_02090	2.78e-158	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
PKEHELCK_02091	1.91e-124	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
PKEHELCK_02092	1.27e-137	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
PKEHELCK_02093	9.55e-243	-	-	-	S	-	-	-	Cell surface protein
PKEHELCK_02094	4.71e-81	-	-	-	-	-	-	-	-
PKEHELCK_02095	0.0	-	-	-	-	-	-	-	-
PKEHELCK_02096	6.83e-207	XK27_00670	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
PKEHELCK_02097	1.01e-198	WQ51_06230	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
PKEHELCK_02098	4.21e-150	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
PKEHELCK_02099	0.0	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
PKEHELCK_02100	3.29e-153	ydgI3	-	-	C	-	-	-	Nitroreductase family
PKEHELCK_02101	2.21e-154	yceE	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
PKEHELCK_02102	5.85e-204	ccpB	-	-	K	-	-	-	lacI family
PKEHELCK_02103	7.39e-121	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
PKEHELCK_02104	5.8e-94	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
PKEHELCK_02105	4.19e-294	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
PKEHELCK_02106	9.86e-117	-	-	-	-	-	-	-	-
PKEHELCK_02107	0.0	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
PKEHELCK_02108	1.06e-205	-	-	-	K	-	-	-	LysR substrate binding domain
PKEHELCK_02109	1.85e-201	-	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NADH pyrophosphatase zinc ribbon domain
PKEHELCK_02110	0.0	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
PKEHELCK_02111	0.0	lepA2	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PKEHELCK_02112	6.88e-152	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PKEHELCK_02113	1.6e-261	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
PKEHELCK_02114	5.44e-88	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
PKEHELCK_02115	4.55e-229	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
PKEHELCK_02116	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
PKEHELCK_02117	1.17e-193	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
PKEHELCK_02118	3.71e-83	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
PKEHELCK_02119	1.5e-193	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
PKEHELCK_02120	4.01e-96	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
PKEHELCK_02121	2.47e-168	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
PKEHELCK_02122	9.16e-209	-	-	-	GM	-	-	-	NmrA-like family
PKEHELCK_02123	3.74e-120	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PKEHELCK_02124	3.88e-218	fhuG	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PKEHELCK_02125	1.2e-151	fhuB	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PKEHELCK_02126	1.92e-45	fhuB	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PKEHELCK_02127	1.06e-186	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
PKEHELCK_02128	4.42e-106	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
PKEHELCK_02129	1.15e-78	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
PKEHELCK_02130	8.84e-140	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PKEHELCK_02131	0.0	yfjF	-	-	U	-	-	-	Sugar (and other) transporter
PKEHELCK_02132	1.33e-227	ydhF	-	-	S	-	-	-	Aldo keto reductase
PKEHELCK_02133	1.09e-130	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
PKEHELCK_02134	3.47e-244	-	1.1.1.219	-	GM	ko:K00091	-	ko00000,ko01000	Male sterility protein
PKEHELCK_02135	5.56e-124	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PKEHELCK_02136	3.27e-170	-	-	-	S	-	-	-	KR domain
PKEHELCK_02137	2.99e-82	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
PKEHELCK_02138	1.62e-62	-	-	-	S	-	-	-	Domain of unknown function (DUF1905)
PKEHELCK_02139	6.12e-29	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
PKEHELCK_02140	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
PKEHELCK_02141	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
PKEHELCK_02142	5.13e-214	-	-	-	GM	-	-	-	NmrA-like family
PKEHELCK_02143	1.46e-126	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PKEHELCK_02144	1.77e-282	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
PKEHELCK_02145	1.55e-171	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
PKEHELCK_02146	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
PKEHELCK_02147	7.81e-148	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
PKEHELCK_02148	7.35e-272	-	-	-	EGP	-	-	-	Major Facilitator
PKEHELCK_02149	3.25e-81	ytcD	-	-	K	-	-	-	Transcriptional regulator, HxlR family
PKEHELCK_02150	4.31e-149	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
PKEHELCK_02151	4.13e-157	-	-	-	-	-	-	-	-
PKEHELCK_02152	1.01e-304	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
PKEHELCK_02153	1.47e-83	-	-	-	-	-	-	-	-
PKEHELCK_02154	2.7e-131	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
PKEHELCK_02155	1.8e-235	ynjC	-	-	S	-	-	-	Cell surface protein
PKEHELCK_02156	4.03e-61	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
PKEHELCK_02157	1.01e-64	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
PKEHELCK_02158	1.27e-90	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
PKEHELCK_02159	2.67e-225	-	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
PKEHELCK_02160	6.02e-137	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
PKEHELCK_02161	1.15e-187	-	-	-	S	-	-	-	Cell surface protein
PKEHELCK_02162	1.54e-216	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
PKEHELCK_02163	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
PKEHELCK_02164	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PKEHELCK_02165	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
PKEHELCK_02166	2.4e-230	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
PKEHELCK_02167	0.0	-	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
PKEHELCK_02168	1.92e-209	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
PKEHELCK_02169	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
PKEHELCK_02170	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
PKEHELCK_02171	3.68e-206	mleR	-	-	K	-	-	-	LysR substrate binding domain
PKEHELCK_02172	0.0	-	-	-	M	-	-	-	domain protein
PKEHELCK_02174	1.03e-201	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
PKEHELCK_02175	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
PKEHELCK_02176	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
PKEHELCK_02177	1.31e-102	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
PKEHELCK_02178	1.19e-277	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PKEHELCK_02179	2.51e-259	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PKEHELCK_02180	1.11e-146	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
PKEHELCK_02181	2.49e-229	yghZ	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
PKEHELCK_02182	6.33e-46	-	-	-	-	-	-	-	-
PKEHELCK_02183	1.35e-78	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
PKEHELCK_02184	1.53e-208	fbpA	-	-	K	-	-	-	Domain of unknown function (DUF814)
PKEHELCK_02185	1.29e-278	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PKEHELCK_02186	3.81e-18	-	-	-	-	-	-	-	-
PKEHELCK_02187	3.18e-77	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PKEHELCK_02188	5.66e-74	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PKEHELCK_02189	2.37e-93	-	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
PKEHELCK_02190	4.65e-192	-	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
PKEHELCK_02191	1.5e-150	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
PKEHELCK_02192	0.0	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
PKEHELCK_02193	4.77e-130	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC transporter permease
PKEHELCK_02194	6.07e-117	gpo	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
PKEHELCK_02195	5.3e-202	dkgB	-	-	S	-	-	-	reductase
PKEHELCK_02196	5.23e-102	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PKEHELCK_02197	1.2e-91	-	-	-	-	-	-	-	-
PKEHELCK_02198	2.32e-43	ygzD	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional
PKEHELCK_02199	3.16e-170	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PKEHELCK_02201	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
PKEHELCK_02202	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
PKEHELCK_02203	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
PKEHELCK_02204	5.33e-103	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PKEHELCK_02205	2.61e-282	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
PKEHELCK_02206	1.21e-111	-	-	-	-	-	-	-	-
PKEHELCK_02207	4.81e-76	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
PKEHELCK_02208	4.17e-67	-	-	-	-	-	-	-	-
PKEHELCK_02209	7.09e-125	-	-	-	-	-	-	-	-
PKEHELCK_02210	1.67e-177	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
PKEHELCK_02211	9.33e-195	gntR	-	-	K	-	-	-	rpiR family
PKEHELCK_02212	1.94e-213	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
PKEHELCK_02213	1.66e-305	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PKEHELCK_02214	0.0	yfgQ	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
PKEHELCK_02215	5.56e-130	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PKEHELCK_02216	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PKEHELCK_02217	1.59e-242	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
PKEHELCK_02218	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PKEHELCK_02219	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
PKEHELCK_02220	5.11e-67	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PKEHELCK_02221	9.48e-263	camS	-	-	S	-	-	-	sex pheromone
PKEHELCK_02222	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PKEHELCK_02223	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
PKEHELCK_02224	1.39e-279	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PKEHELCK_02225	1.13e-120	yebE	-	-	S	-	-	-	UPF0316 protein
PKEHELCK_02226	8.19e-134	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PKEHELCK_02227	1.39e-145	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
PKEHELCK_02228	3.86e-235	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
PKEHELCK_02229	4.92e-212	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
PKEHELCK_02230	1.39e-233	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
PKEHELCK_02231	1.89e-208	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
PKEHELCK_02232	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
PKEHELCK_02233	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
PKEHELCK_02234	7.76e-234	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
PKEHELCK_02235	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
PKEHELCK_02236	0.0	-	-	-	S	ko:K06889	-	ko00000	Alpha beta
PKEHELCK_02237	6.07e-33	-	-	-	-	-	-	-	-
PKEHELCK_02238	6.47e-128	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
PKEHELCK_02239	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
PKEHELCK_02240	2.6e-212	mleP2	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
PKEHELCK_02241	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
PKEHELCK_02242	6.5e-215	mleR	-	-	K	-	-	-	LysR family
PKEHELCK_02243	3.06e-205	mleR2	-	-	K	-	-	-	LysR family transcriptional regulator
PKEHELCK_02244	1.15e-121	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
PKEHELCK_02245	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
PKEHELCK_02246	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
PKEHELCK_02247	2.05e-231	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
PKEHELCK_02248	1.38e-19	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
PKEHELCK_02253	3.64e-82	-	-	-	-	-	-	-	-
PKEHELCK_02254	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
PKEHELCK_02255	2.83e-114	-	-	-	-	-	-	-	-
PKEHELCK_02256	2.83e-138	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PKEHELCK_02257	2.62e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PKEHELCK_02258	5.87e-256	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PKEHELCK_02259	9.91e-289	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
PKEHELCK_02260	1.32e-63	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
PKEHELCK_02261	2.48e-276	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PKEHELCK_02262	8.32e-227	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
PKEHELCK_02263	2.79e-316	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
PKEHELCK_02264	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PKEHELCK_02265	5e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
PKEHELCK_02266	5.39e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PKEHELCK_02267	1.31e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
PKEHELCK_02268	1.06e-49	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
PKEHELCK_02269	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PKEHELCK_02270	3e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
PKEHELCK_02271	1.45e-161	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
PKEHELCK_02272	5.06e-194	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
PKEHELCK_02273	8.49e-144	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PKEHELCK_02274	4.03e-125	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
PKEHELCK_02275	7.94e-114	ykuL	-	-	S	-	-	-	(CBS) domain
PKEHELCK_02276	2.29e-112	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
PKEHELCK_02277	6.72e-289	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
PKEHELCK_02278	2.31e-202	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
PKEHELCK_02279	1.88e-75	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PKEHELCK_02280	1.6e-96	-	-	-	-	-	-	-	-
PKEHELCK_02281	9.11e-106	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
PKEHELCK_02282	8.96e-275	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
PKEHELCK_02283	4.47e-231	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
PKEHELCK_02284	7.88e-211	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
PKEHELCK_02285	2.44e-65	-	-	-	S	ko:K09004	-	ko00000	DsrE/DsrF-like family
PKEHELCK_02286	2.21e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
PKEHELCK_02287	2.06e-205	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PKEHELCK_02288	2.57e-224	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
PKEHELCK_02289	6.2e-242	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
PKEHELCK_02290	1.97e-72	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
PKEHELCK_02291	3.53e-107	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
PKEHELCK_02292	3.03e-27	-	-	-	-	ko:K02671	-	ko00000,ko02035,ko02044	-
PKEHELCK_02293	6.46e-113	-	-	-	S	-	-	-	Prokaryotic N-terminal methylation motif
PKEHELCK_02295	3.16e-236	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
PKEHELCK_02296	4.7e-282	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PKEHELCK_02297	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
PKEHELCK_02298	1.66e-150	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
PKEHELCK_02299	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
PKEHELCK_02300	1.96e-116	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
PKEHELCK_02301	7.18e-189	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
PKEHELCK_02302	4.69e-151	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
PKEHELCK_02303	8.38e-152	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
PKEHELCK_02304	5.16e-141	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PKEHELCK_02305	2e-98	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	general stress protein
PKEHELCK_02306	1.11e-84	-	-	-	-	-	-	-	-
PKEHELCK_02307	4.96e-247	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
PKEHELCK_02308	3.19e-285	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
PKEHELCK_02309	4.94e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
PKEHELCK_02310	4.88e-276	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
PKEHELCK_02311	5.85e-158	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PKEHELCK_02312	7.74e-47	-	-	-	-	-	-	-	-
PKEHELCK_02313	3.51e-125	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
PKEHELCK_02314	4.04e-241	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PKEHELCK_02315	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PKEHELCK_02316	6.52e-124	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
PKEHELCK_02317	2.06e-187	ylmH	-	-	S	-	-	-	S4 domain protein
PKEHELCK_02318	6.45e-49	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
PKEHELCK_02319	1.56e-93	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
PKEHELCK_02320	9.39e-295	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PKEHELCK_02321	3.55e-312	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
PKEHELCK_02322	2.34e-208	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
PKEHELCK_02323	5e-253	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PKEHELCK_02324	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PKEHELCK_02325	2.81e-231	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PKEHELCK_02326	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
PKEHELCK_02327	7.01e-76	ftsL	-	-	D	-	-	-	Cell division protein FtsL
PKEHELCK_02328	1.74e-224	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PKEHELCK_02329	1.14e-100	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
PKEHELCK_02330	5.35e-81	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
PKEHELCK_02331	4.1e-223	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
PKEHELCK_02332	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
PKEHELCK_02333	1.41e-124	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PKEHELCK_02334	2.5e-147	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
PKEHELCK_02335	3.59e-301	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
PKEHELCK_02337	4.55e-207	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
PKEHELCK_02338	4.82e-55	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PKEHELCK_02339	9.52e-264	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
PKEHELCK_02340	2.68e-75	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
PKEHELCK_02341	1.6e-246	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
PKEHELCK_02342	7.21e-150	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
PKEHELCK_02343	6.31e-222	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
PKEHELCK_02344	1.29e-193	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PKEHELCK_02345	9.08e-157	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
PKEHELCK_02346	2.24e-148	yjbH	-	-	Q	-	-	-	Thioredoxin
PKEHELCK_02347	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
PKEHELCK_02348	2.25e-264	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
PKEHELCK_02349	7.12e-170	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
PKEHELCK_02350	9.28e-89	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PKEHELCK_02351	2.81e-178	yhfI	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
PKEHELCK_02352	1.08e-117	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
PKEHELCK_02373	9.94e-267	pmrB	-	-	EGP	-	-	-	Major Facilitator Superfamily
PKEHELCK_02374	4.87e-191	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
PKEHELCK_02375	2.37e-65	-	-	-	-	-	-	-	-
PKEHELCK_02376	2.29e-36	-	-	-	-	-	-	-	-
PKEHELCK_02377	4.81e-169	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
PKEHELCK_02378	2.47e-101	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
PKEHELCK_02379	1.11e-205	-	-	-	S	-	-	-	EDD domain protein, DegV family
PKEHELCK_02380	1.97e-87	-	-	-	K	-	-	-	Transcriptional regulator
PKEHELCK_02381	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
PKEHELCK_02382	2.28e-171	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
PKEHELCK_02383	2.41e-205	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PKEHELCK_02384	1.27e-115	-	-	-	F	-	-	-	NUDIX domain
PKEHELCK_02386	3.42e-176	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2087)
PKEHELCK_02387	2.08e-92	-	-	-	S	-	-	-	LuxR family transcriptional regulator
PKEHELCK_02388	2.24e-167	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	Chloramphenicol acetyltransferase
PKEHELCK_02390	7.75e-93	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
PKEHELCK_02391	2.01e-145	-	-	-	G	-	-	-	Phosphoglycerate mutase family
PKEHELCK_02392	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
PKEHELCK_02393	1.71e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
PKEHELCK_02394	1.9e-115	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PKEHELCK_02395	9.72e-225	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
PKEHELCK_02396	1.65e-97	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PKEHELCK_02397	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
PKEHELCK_02398	5.04e-82	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
PKEHELCK_02399	3.28e-87	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
PKEHELCK_02400	8.53e-268	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	FAD dependent oxidoreductase
PKEHELCK_02401	3.69e-187	-	-	-	S	-	-	-	hydrolase activity, acting on ester bonds
PKEHELCK_02402	6.79e-249	-	-	-	-	-	-	-	-
PKEHELCK_02403	1.9e-156	-	-	-	P	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
PKEHELCK_02404	4.35e-159	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
PKEHELCK_02405	1.38e-232	-	-	-	V	-	-	-	LD-carboxypeptidase
PKEHELCK_02406	2.04e-310	-	-	-	M	ko:K07273	-	ko00000	hydrolase, family 25
PKEHELCK_02407	1.66e-101	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
PKEHELCK_02408	3.46e-267	mccF	-	-	V	-	-	-	LD-carboxypeptidase
PKEHELCK_02409	9.63e-307	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
PKEHELCK_02410	9.19e-95	-	-	-	S	-	-	-	SnoaL-like domain
PKEHELCK_02411	4.17e-186	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
PKEHELCK_02412	1.55e-309	-	-	-	P	-	-	-	Major Facilitator Superfamily
PKEHELCK_02413	5.13e-61	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
PKEHELCK_02414	1.44e-282	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
PKEHELCK_02416	9.98e-75	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
PKEHELCK_02417	2.12e-142	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
PKEHELCK_02418	3.6e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PKEHELCK_02419	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
PKEHELCK_02420	8.03e-229	phnT	3.6.3.30	-	P	ko:K02010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
PKEHELCK_02421	1.43e-12	ftpB	-	-	P	ko:K02012	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
PKEHELCK_02422	2.05e-166	ftpB	-	-	P	ko:K02012	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
PKEHELCK_02423	1.61e-243	ftpA	-	-	P	ko:K02011	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PKEHELCK_02424	1e-88	-	-	-	-	-	-	-	-
PKEHELCK_02425	8.08e-105	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
PKEHELCK_02426	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
PKEHELCK_02427	2.21e-127	-	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
PKEHELCK_02428	3.26e-160	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
PKEHELCK_02429	2.03e-295	pts3C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PKEHELCK_02430	3.56e-52	-	-	-	-	-	-	-	-
PKEHELCK_02431	1.86e-269	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
PKEHELCK_02432	2.94e-261	dho	3.5.2.3	-	S	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Amidohydrolase family
PKEHELCK_02433	4.64e-255	selA	2.9.1.1	-	H	ko:K01042	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko01000	L-seryl-tRNA selenium transferase
PKEHELCK_02434	5.81e-165	-	4.1.2.14	-	S	ko:K17463	ko00030,ko01100,ko01120,map00030,map01100,map01120	ko00000,ko00001,ko00002,ko01000	KDGP aldolase
PKEHELCK_02435	6.09e-236	-	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
PKEHELCK_02436	6.1e-124	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Bacterial transferase hexapeptide (six repeats)
PKEHELCK_02437	2.25e-265	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
PKEHELCK_02438	1.3e-211	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
PKEHELCK_02439	6.72e-203	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
PKEHELCK_02440	3.65e-181	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
PKEHELCK_02443	3.34e-217	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
PKEHELCK_02444	2.39e-166	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
PKEHELCK_02445	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
PKEHELCK_02446	0.0	pts4ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PKEHELCK_02447	0.0	pts5ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
PKEHELCK_02448	2.6e-185	-	-	-	-	-	-	-	-
PKEHELCK_02449	1.21e-94	tagD	2.7.7.15, 2.7.7.39	-	IM	ko:K00968,ko:K00980	ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231	ko00000,ko00001,ko00002,ko01000	Glycerol-3-phosphate cytidylyltransferase
PKEHELCK_02450	1.95e-294	tagB	2.7.8.12, 2.7.8.45	-	M	ko:K09809,ko:K21591	-	ko00000,ko01000	glycerophosphotransferase
PKEHELCK_02451	0.0	tagB	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	glycerophosphotransferase
PKEHELCK_02452	0.0	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
PKEHELCK_02453	3.37e-129	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
PKEHELCK_02454	9.53e-93	-	-	-	-	-	-	-	-
PKEHELCK_02455	8.9e-96	ywnA	-	-	K	-	-	-	Transcriptional regulator
PKEHELCK_02456	5.2e-156	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PKEHELCK_02457	5.71e-301	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
PKEHELCK_02458	1.15e-152	-	-	-	-	-	-	-	-
PKEHELCK_02459	2.92e-57	-	-	-	-	-	-	-	-
PKEHELCK_02460	1.55e-55	-	-	-	-	-	-	-	-
PKEHELCK_02461	0.0	ydiC	-	-	EGP	-	-	-	Major Facilitator
PKEHELCK_02462	8.98e-86	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
PKEHELCK_02463	1.53e-60	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
PKEHELCK_02464	2.59e-69	-	-	-	-	-	-	-	-
PKEHELCK_02465	2.54e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
PKEHELCK_02466	2.77e-41	-	-	-	-	-	-	-	-
PKEHELCK_02467	3.31e-35	-	-	-	-	-	-	-	-
PKEHELCK_02468	3.82e-128	-	-	-	K	-	-	-	DNA-templated transcription, initiation
PKEHELCK_02469	1.39e-169	-	-	-	-	-	-	-	-
PKEHELCK_02470	3.93e-180	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
PKEHELCK_02471	6.62e-138	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
PKEHELCK_02472	5.34e-168	lytE	-	-	M	-	-	-	NlpC/P60 family
PKEHELCK_02473	8.01e-64	-	-	-	K	-	-	-	sequence-specific DNA binding
PKEHELCK_02474	7.17e-39	-	-	-	S	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
PKEHELCK_02475	4.22e-215	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
PKEHELCK_02476	1.13e-257	yueF	-	-	S	-	-	-	AI-2E family transporter
PKEHELCK_02477	3.5e-93	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
PKEHELCK_02478	7.89e-290	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
PKEHELCK_02479	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
PKEHELCK_02480	4.77e-216	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
PKEHELCK_02481	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
PKEHELCK_02482	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PKEHELCK_02483	0.0	-	-	-	-	-	-	-	-
PKEHELCK_02484	2.12e-252	-	-	-	M	-	-	-	MucBP domain
PKEHELCK_02485	1.36e-208	lysR5	-	-	K	-	-	-	LysR substrate binding domain
PKEHELCK_02486	5.93e-165	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
PKEHELCK_02487	3.85e-76	ywjH	-	-	S	-	-	-	Protein of unknown function (DUF1634)
PKEHELCK_02488	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
PKEHELCK_02489	3.44e-210	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PKEHELCK_02490	3.59e-241	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PKEHELCK_02491	2.81e-257	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PKEHELCK_02492	5.67e-231	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PKEHELCK_02493	3.4e-85	-	-	-	K	-	-	-	Winged helix DNA-binding domain
PKEHELCK_02494	2.5e-132	-	-	-	L	-	-	-	Integrase
PKEHELCK_02495	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
PKEHELCK_02496	5.6e-41	-	-	-	-	-	-	-	-
PKEHELCK_02497	1.24e-52	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
PKEHELCK_02498	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PKEHELCK_02499	1.41e-285	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
PKEHELCK_02500	2.04e-254	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
PKEHELCK_02501	2.16e-241	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PKEHELCK_02502	3.79e-291	dacA2	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
PKEHELCK_02503	5.8e-291	araT	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
PKEHELCK_02504	1.56e-46	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
PKEHELCK_02505	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PKEHELCK_02506	1.13e-190	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
PKEHELCK_02507	3.43e-96	-	-	-	S	-	-	-	COG NOG18757 non supervised orthologous group
PKEHELCK_02508	4.26e-54	-	-	-	-	-	-	-	-
PKEHELCK_02509	3.27e-96	copR	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
PKEHELCK_02510	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
PKEHELCK_02511	4.38e-243	pva2	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
PKEHELCK_02512	1.47e-144	-	-	-	S	-	-	-	VIT family
PKEHELCK_02513	2.66e-155	-	-	-	S	-	-	-	membrane
PKEHELCK_02514	1.9e-202	-	-	-	EG	-	-	-	EamA-like transporter family
PKEHELCK_02515	2.52e-107	-	-	-	S	ko:K02348	-	ko00000	GNAT family
PKEHELCK_02516	3.57e-150	-	-	-	GM	-	-	-	NmrA-like family
PKEHELCK_02517	4.79e-21	-	-	-	-	-	-	-	-
PKEHELCK_02518	3.78e-73	-	-	-	-	-	-	-	-
PKEHELCK_02519	4.58e-103	hsp3	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
PKEHELCK_02520	1.36e-112	-	-	-	-	-	-	-	-
PKEHELCK_02521	1.22e-81	-	-	-	-	-	-	-	-
PKEHELCK_02522	4.98e-275	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
PKEHELCK_02523	1.7e-70	-	-	-	-	-	-	-	-
PKEHELCK_02524	3.46e-87	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
PKEHELCK_02525	9.97e-94	spxA	-	-	P	ko:K16509	-	ko00000	ArsC family
PKEHELCK_02526	2.14e-86	-	-	-	K	ko:K22296	-	ko00000,ko03000	Winged helix DNA-binding domain
PKEHELCK_02527	6.47e-208	-	-	-	GM	-	-	-	NmrA-like family
PKEHELCK_02528	4.75e-112	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
PKEHELCK_02529	4.28e-216	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
PKEHELCK_02530	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
PKEHELCK_02531	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
PKEHELCK_02532	1.19e-34	-	-	-	S	-	-	-	Belongs to the LOG family
PKEHELCK_02533	1.18e-254	glmS2	-	-	M	-	-	-	SIS domain
PKEHELCK_02534	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
PKEHELCK_02535	2.16e-278	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
PKEHELCK_02536	2.32e-160	-	-	-	S	-	-	-	YjbR
PKEHELCK_02538	0.0	cadA	-	-	P	-	-	-	P-type ATPase
PKEHELCK_02539	0.0	-	-	-	U	ko:K03451	-	ko00000	Belongs to the BCCT transporter (TC 2.A.15) family
PKEHELCK_02540	8.79e-156	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
PKEHELCK_02541	4.29e-101	-	-	-	-	-	-	-	-
PKEHELCK_02542	8.46e-50	-	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
PKEHELCK_02543	2.42e-127	-	-	-	FG	-	-	-	HIT domain
PKEHELCK_02544	6.07e-223	ydhF	-	-	S	-	-	-	Aldo keto reductase
PKEHELCK_02545	8.93e-71	-	-	-	S	-	-	-	Pfam:DUF59
PKEHELCK_02546	1.12e-206	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PKEHELCK_02547	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
PKEHELCK_02548	1.26e-247	-	-	-	V	-	-	-	Beta-lactamase
PKEHELCK_02549	3.74e-125	-	-	-	V	-	-	-	VanZ like family
PKEHELCK_02550	9.31e-46	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC
PKEHELCK_02551	9.48e-265	-	-	-	EGP	-	-	-	Major facilitator Superfamily
PKEHELCK_02552	7.97e-222	ropB	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PKEHELCK_02553	3.3e-296	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
PKEHELCK_02554	4.13e-293	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
PKEHELCK_02555	1.56e-16	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
PKEHELCK_02556	2.85e-206	-	-	-	I	-	-	-	alpha/beta hydrolase fold
PKEHELCK_02557	6.11e-169	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
PKEHELCK_02558	9.97e-18	-	-	-	-	-	-	-	-
PKEHELCK_02559	0.0	-	-	-	-	-	-	-	-
PKEHELCK_02560	2e-52	-	-	-	S	-	-	-	Cytochrome B5
PKEHELCK_02561	8.68e-118	pts21A	-	-	G	ko:K02755	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
PKEHELCK_02562	4.14e-279	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
PKEHELCK_02563	1.63e-162	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
PKEHELCK_02564	3.83e-135	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PKEHELCK_02565	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
PKEHELCK_02566	1.56e-108	-	-	-	-	-	-	-	-
PKEHELCK_02567	6.98e-95	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
PKEHELCK_02568	3.08e-241	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PKEHELCK_02569	1.26e-245	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PKEHELCK_02570	7.16e-30	-	-	-	-	-	-	-	-
PKEHELCK_02571	1.84e-134	-	-	-	-	-	-	-	-
PKEHELCK_02572	3.46e-210	-	-	-	K	-	-	-	LysR substrate binding domain
PKEHELCK_02573	3.88e-174	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
PKEHELCK_02574	2.96e-105	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
PKEHELCK_02575	0.0	-	4.1.1.98	-	H	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
PKEHELCK_02576	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
PKEHELCK_02577	1.61e-183	-	-	-	S	-	-	-	zinc-ribbon domain
PKEHELCK_02579	4.29e-50	-	-	-	-	-	-	-	-
PKEHELCK_02580	1.48e-171	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
PKEHELCK_02581	2.35e-231	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
PKEHELCK_02582	0.0	-	-	-	I	-	-	-	acetylesterase activity
PKEHELCK_02583	1.12e-251	-	-	-	M	-	-	-	Collagen binding domain
PKEHELCK_02584	8.08e-205	yicL	-	-	EG	-	-	-	EamA-like transporter family
PKEHELCK_02585	3.03e-166	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
PKEHELCK_02586	1.44e-226	-	4.1.1.52	-	S	ko:K22213	-	ko00000,ko01000	Amidohydrolase
PKEHELCK_02587	3.29e-141	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
PKEHELCK_02588	1.85e-51	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
PKEHELCK_02589	4.54e-208	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
PKEHELCK_02590	7.27e-46	-	-	-	S	-	-	-	Cell surface protein
PKEHELCK_02591	2.69e-99	-	-	-	-	-	-	-	-
PKEHELCK_02592	0.0	-	-	-	-	-	-	-	-
PKEHELCK_02593	3.05e-289	hpk9	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
PKEHELCK_02594	1.47e-51	-	-	-	S	ko:K07343	-	ko00000	TfoX C-terminal domain
PKEHELCK_02595	2.81e-181	-	-	-	K	-	-	-	Helix-turn-helix domain
PKEHELCK_02596	0.0	aapA	-	-	M	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
PKEHELCK_02597	1.01e-221	aapA	-	-	M	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
PKEHELCK_02598	1.36e-84	-	-	-	S	-	-	-	Cupredoxin-like domain
PKEHELCK_02599	1.49e-58	-	-	-	S	-	-	-	Cupredoxin-like domain
PKEHELCK_02600	0.0	copA	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
PKEHELCK_02601	2.65e-269	adhC	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
PKEHELCK_02602	1.71e-285	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
PKEHELCK_02603	1.95e-85	lysM	-	-	M	-	-	-	LysM domain
PKEHELCK_02604	0.0	-	-	-	E	-	-	-	Amino Acid
PKEHELCK_02605	2.47e-185	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PKEHELCK_02606	1.97e-92	-	-	-	-	-	-	-	-
PKEHELCK_02608	2.96e-209	yhxD	-	-	IQ	-	-	-	KR domain
PKEHELCK_02609	1.26e-287	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
PKEHELCK_02610	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
PKEHELCK_02611	5.53e-131	-	-	-	V	ko:K06147,ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PKEHELCK_02612	1.85e-252	-	-	-	V	ko:K06147,ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PKEHELCK_02613	7.71e-276	-	-	-	-	-	-	-	-
PKEHELCK_02614	2.4e-151	-	-	-	GM	-	-	-	NAD(P)H-binding
PKEHELCK_02615	3.83e-178	gdh	1.1.1.47, 1.1.1.53	-	IQ	ko:K00034,ko:K00038	ko00030,ko00140,ko01100,ko01120,ko01200,map00030,map00140,map01100,map01120,map01200	ko00000,ko00001,ko01000	reductase
PKEHELCK_02616	3.55e-79	-	-	-	I	-	-	-	sulfurtransferase activity
PKEHELCK_02617	6.7e-102	yphH	-	-	S	-	-	-	Cupin domain
PKEHELCK_02618	1.37e-119	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
PKEHELCK_02619	2.15e-151	-	-	-	GM	-	-	-	NAD(P)H-binding
PKEHELCK_02620	8.84e-221	-	-	-	C	-	-	-	C4-dicarboxylate transmembrane transporter activity
PKEHELCK_02621	6.54e-168	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
PKEHELCK_02622	7.99e-92	-	-	-	-	-	-	-	-
PKEHELCK_02623	1.66e-214	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
PKEHELCK_02624	1.56e-56	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PKEHELCK_02625	1e-98	-	-	-	S	ko:K06889	-	ko00000	X-Pro dipeptidyl-peptidase (S15 family)
PKEHELCK_02626	6.61e-77	-	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
PKEHELCK_02628	7.95e-58	-	-	-	K	-	-	-	LysR substrate binding domain
PKEHELCK_02629	1.03e-248	-	-	-	C	-	-	-	FMN_bind
PKEHELCK_02630	1.05e-191	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
PKEHELCK_02631	5.17e-07	-	-	-	-	-	-	-	-
PKEHELCK_02632	1.56e-58	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
PKEHELCK_02633	4.33e-190	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
PKEHELCK_02635	1.99e-66	-	-	-	-	-	-	-	-
PKEHELCK_02636	2.83e-58	-	-	-	L	-	-	-	Addiction module antitoxin, RelB DinJ family
PKEHELCK_02637	1.35e-38	-	-	-	-	-	-	-	-
PKEHELCK_02638	2.06e-109	-	-	-	S	-	-	-	protein conserved in bacteria
PKEHELCK_02639	9.32e-274	-	-	-	L	-	-	-	Transposase DDE domain group 1
PKEHELCK_02640	9.43e-79	-	-	-	M	-	-	-	Glycosyltransferase like family 2
PKEHELCK_02641	2.89e-48	-	-	-	M	-	-	-	Glycosyl transferases group 1
PKEHELCK_02642	5.24e-52	-	-	GT4	M	ko:K02840	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Glycosyl transferases group 1
PKEHELCK_02644	3.18e-31	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
PKEHELCK_02645	1.59e-21	-	-	-	GM	ko:K19426	-	ko00000,ko01000	Polysaccharide pyruvyl transferase
PKEHELCK_02646	2.15e-87	cps2I	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
PKEHELCK_02647	3.34e-26	epsJ	-	GT2	S	ko:K19427	-	ko00000,ko01000	COG0463 Glycosyltransferases involved in cell wall biogenesis
PKEHELCK_02648	3.33e-221	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
PKEHELCK_02649	2.04e-18	-	-	-	-	-	-	-	-
PKEHELCK_02650	2.69e-175	-	-	-	L	-	-	-	Transposase IS66 family
PKEHELCK_02652	1.66e-09	-	-	-	-	-	-	-	-
PKEHELCK_02653	1.14e-57	-	-	-	L	ko:K07484	-	ko00000	IS66 Orf2 like protein
PKEHELCK_02654	1.88e-76	-	-	-	L	-	-	-	Transposase IS66 family
PKEHELCK_02656	6.08e-58	-	-	-	L	-	-	-	COG1484 DNA replication protein
PKEHELCK_02657	9.32e-274	-	-	-	L	-	-	-	Transposase DDE domain group 1
PKEHELCK_02658	8.5e-55	-	-	-	-	-	-	-	-
PKEHELCK_02659	1.63e-35	-	-	-	-	-	-	-	-
PKEHELCK_02660	0.0	traA	-	-	L	-	-	-	MobA/MobL family
PKEHELCK_02661	1.27e-176	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
PKEHELCK_02662	1.15e-52	-	-	-	L	ko:K07483	-	ko00000	Transposase
PKEHELCK_02663	6.33e-120	-	-	-	L	-	-	-	4.5 Transposon and IS
PKEHELCK_02664	5.79e-171	epsB	-	-	M	-	-	-	biosynthesis protein
PKEHELCK_02665	8.26e-164	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
PKEHELCK_02666	7.22e-176	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
PKEHELCK_02667	2.4e-153	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
PKEHELCK_02668	7.63e-83	-	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
PKEHELCK_02669	1.03e-174	yesN	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
PKEHELCK_02670	5.48e-171	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
PKEHELCK_02671	6.48e-244	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
PKEHELCK_02672	0.0	-	-	-	-	-	-	-	-
PKEHELCK_02673	1.39e-211	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
PKEHELCK_02674	1.58e-66	-	-	-	-	-	-	-	-
PKEHELCK_02675	6.47e-124	-	-	-	K	ko:K22041	-	ko00000,ko03000	transcriptional regulator
PKEHELCK_02676	5.94e-118	ymdB	-	-	S	-	-	-	Macro domain protein
PKEHELCK_02677	2.69e-190	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
PKEHELCK_02678	1.5e-56	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
PKEHELCK_02679	6.92e-101	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
PKEHELCK_02680	2.57e-171	-	-	-	S	-	-	-	Putative threonine/serine exporter
PKEHELCK_02681	1.36e-209	yvgN	-	-	C	-	-	-	Aldo keto reductase
PKEHELCK_02682	3.27e-204	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
PKEHELCK_02683	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
PKEHELCK_02684	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
PKEHELCK_02685	1.14e-110	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
PKEHELCK_02686	6.1e-101	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
PKEHELCK_02687	2.44e-230	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
PKEHELCK_02688	1.77e-282	mdtG	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
PKEHELCK_02689	1.2e-287	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PKEHELCK_02691	2.81e-126	-	-	-	S	-	-	-	Phage regulatory protein Rha (Phage_pRha)
PKEHELCK_02692	3.92e-56	-	-	-	-	-	-	-	-
PKEHELCK_02693	1.15e-05	-	-	-	-	-	-	-	-
PKEHELCK_02695	2.74e-63	-	-	-	-	-	-	-	-
PKEHELCK_02696	5.68e-40	-	-	-	-	-	-	-	-
PKEHELCK_02697	5.13e-171	-	-	-	L	-	-	-	Primase C terminal 1 (PriCT-1)
PKEHELCK_02698	0.0	-	-	-	S	-	-	-	Virulence-associated protein E
PKEHELCK_02699	1.52e-81	-	-	-	-	-	-	-	-
PKEHELCK_02700	8.12e-90	-	-	-	-	-	-	-	-
PKEHELCK_02701	2.31e-73	-	-	-	-	-	-	-	-
PKEHELCK_02703	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
PKEHELCK_02704	2.41e-84	-	-	-	S	-	-	-	Protein of unknown function (DUF1398)
PKEHELCK_02705	2.55e-65	-	-	-	-	-	-	-	-
PKEHELCK_02706	7.21e-35	-	-	-	-	-	-	-	-
PKEHELCK_02707	3.01e-117	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
PKEHELCK_02708	2.28e-123	ftpA	-	-	P	ko:K02011	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PKEHELCK_02709	2.17e-108	-	-	-	T	-	-	-	Universal stress protein family
PKEHELCK_02710	1.58e-203	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
PKEHELCK_02711	2.45e-142	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PKEHELCK_02712	7.74e-237	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PKEHELCK_02714	3.25e-165	dnaD	-	-	L	ko:K02086	-	ko00000	Replication initiation and membrane attachment
PKEHELCK_02715	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
PKEHELCK_02716	3.1e-289	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
PKEHELCK_02717	2.53e-107	ypmB	-	-	S	-	-	-	protein conserved in bacteria
PKEHELCK_02718	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
PKEHELCK_02719	1.48e-217	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
PKEHELCK_02720	1.1e-230	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
PKEHELCK_02721	3.58e-262	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
PKEHELCK_02722	8.61e-251	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
PKEHELCK_02723	2.76e-246	galM2	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
PKEHELCK_02724	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
PKEHELCK_02725	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
PKEHELCK_02726	1.38e-156	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
PKEHELCK_02727	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
PKEHELCK_02728	3.86e-192	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
PKEHELCK_02729	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
PKEHELCK_02730	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PKEHELCK_02731	3.23e-58	-	-	-	-	-	-	-	-
PKEHELCK_02732	1.25e-66	-	-	-	-	-	-	-	-
PKEHELCK_02733	5.03e-182	-	-	-	U	ko:K10716	-	ko00000,ko02000	Ion channel
PKEHELCK_02734	1.48e-218	-	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
PKEHELCK_02735	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PKEHELCK_02736	8.39e-38	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
PKEHELCK_02737	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
PKEHELCK_02738	1.06e-53	-	-	-	-	-	-	-	-
PKEHELCK_02739	4e-40	-	-	-	S	-	-	-	CsbD-like
PKEHELCK_02740	2.22e-55	-	-	-	S	-	-	-	transglycosylase associated protein
PKEHELCK_02741	5.79e-21	-	-	-	-	-	-	-	-
PKEHELCK_02742	1.51e-48	-	-	-	-	-	-	-	-
PKEHELCK_02743	1.82e-185	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
PKEHELCK_02744	8.76e-220	dgoD	4.2.1.6, 4.2.1.8	-	M	ko:K01684,ko:K08323	ko00040,ko00052,ko01100,ko01120,map00040,map00052,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Mandelate racemase muconate lactonizing enzyme
PKEHELCK_02745	2.18e-185	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
PKEHELCK_02746	1.5e-156	gpm5	-	-	G	-	-	-	Phosphoglycerate mutase family
PKEHELCK_02747	1.12e-130	-	-	-	K	-	-	-	FR47-like protein
PKEHELCK_02748	8.44e-163	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
PKEHELCK_02749	9.39e-278	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
PKEHELCK_02750	1.53e-241	-	-	-	-	-	-	-	-
PKEHELCK_02751	5.03e-180	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
PKEHELCK_02752	5.06e-68	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
PKEHELCK_02753	9.54e-209	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
PKEHELCK_02754	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
PKEHELCK_02755	4.95e-44	-	-	-	L	-	-	-	leucine-zipper of insertion element IS481
PKEHELCK_02756	9.05e-55	-	-	-	-	-	-	-	-
PKEHELCK_02757	6.71e-284	-	-	-	L	-	-	-	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PKEHELCK_02758	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
PKEHELCK_02759	1.38e-254	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
PKEHELCK_02760	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
PKEHELCK_02761	1.3e-134	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PKEHELCK_02762	4.3e-106	-	-	-	K	-	-	-	Transcriptional regulator
PKEHELCK_02764	0.0	-	-	-	C	-	-	-	FMN_bind
PKEHELCK_02765	1.37e-220	-	-	-	K	-	-	-	Transcriptional regulator
PKEHELCK_02766	2.67e-124	-	-	-	K	-	-	-	Helix-turn-helix domain
PKEHELCK_02767	2.49e-178	-	-	-	K	-	-	-	sequence-specific DNA binding
PKEHELCK_02768	2.48e-63	-	-	-	S	-	-	-	AAA domain
PKEHELCK_02769	9.7e-34	-	-	-	S	-	-	-	AAA domain
PKEHELCK_02770	1.42e-08	-	-	-	-	-	-	-	-
PKEHELCK_02771	0.0	-	-	-	M	-	-	-	MucBP domain
PKEHELCK_02772	1.39e-118	XK27_09665	-	-	G	ko:K15640	-	ko00000	Phosphoglycerate mutase family
PKEHELCK_02773	2.44e-63	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
PKEHELCK_02774	4.61e-222	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PKEHELCK_02777	6.19e-208	-	-	-	K	-	-	-	Transcriptional regulator
PKEHELCK_02778	2.95e-207	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
PKEHELCK_02779	1.93e-210	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
PKEHELCK_02780	2.45e-101	-	-	-	K	-	-	-	Winged helix DNA-binding domain
PKEHELCK_02781	0.0	ycaM	-	-	E	-	-	-	amino acid
PKEHELCK_02782	2.1e-165	aroC1	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Type I 3-dehydroquinase
PKEHELCK_02783	4.3e-44	-	-	-	-	-	-	-	-
PKEHELCK_02784	0.0	-	-	-	M	-	-	-	Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
PKEHELCK_02785	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
PKEHELCK_02786	1.17e-101	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
PKEHELCK_02787	0.0	-	-	-	-	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	-
PKEHELCK_02788	1.08e-131	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
PKEHELCK_02789	4.12e-226	serA1	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
PKEHELCK_02790	2.8e-204	-	-	-	EG	-	-	-	EamA-like transporter family
PKEHELCK_02791	2.05e-233	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PKEHELCK_02792	5.06e-196	-	-	-	S	-	-	-	hydrolase
PKEHELCK_02793	7.63e-107	-	-	-	-	-	-	-	-
PKEHELCK_02794	1.75e-156	pgm7	-	-	G	-	-	-	Phosphoglycerate mutase family
PKEHELCK_02795	1.4e-181	epsV	-	-	S	-	-	-	glycosyl transferase family 2
PKEHELCK_02796	6.37e-169	gntR	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
PKEHELCK_02797	1.86e-64	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
PKEHELCK_02798	6.7e-74	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
PKEHELCK_02799	0.0	pbg5	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
PKEHELCK_02800	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
PKEHELCK_02801	8.58e-316	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
PKEHELCK_02802	4.29e-173	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
PKEHELCK_02803	7.85e-155	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
PKEHELCK_02804	9.62e-73	-	-	-	-	-	-	-	-
PKEHELCK_02807	3.81e-33	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
PKEHELCK_02810	1.41e-154	-	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
PKEHELCK_02816	0.0	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	C-terminal repeat of topoisomerase
PKEHELCK_02818	3.02e-14	XK27_07075	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
PKEHELCK_02828	6.77e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF3102)
PKEHELCK_02830	1.08e-121	-	-	-	M	-	-	-	CHAP domain
PKEHELCK_02832	4.78e-118	-	-	-	S	-	-	-	COG0433 Predicted ATPase
PKEHELCK_02837	4.64e-255	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
PKEHELCK_02838	0.0	pox4	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
PKEHELCK_02839	5.03e-95	-	-	-	K	-	-	-	Transcriptional regulator
PKEHELCK_02840	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
PKEHELCK_02841	6.96e-83	pts38A	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
PKEHELCK_02842	5.88e-233	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
PKEHELCK_02843	1.44e-128	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
PKEHELCK_02844	3.33e-113	srlM1	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
PKEHELCK_02845	0.0	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
PKEHELCK_02846	1.56e-185	srlD2	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
PKEHELCK_02847	2.53e-209	rbsU	-	-	U	ko:K06216	-	ko00000,ko02000	ribose uptake protein RbsU
PKEHELCK_02848	4.99e-88	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
PKEHELCK_02849	7.82e-210	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PKEHELCK_02850	4.04e-241	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
PKEHELCK_02851	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
PKEHELCK_02852	7.2e-103	-	-	-	T	-	-	-	Universal stress protein family
PKEHELCK_02853	7.43e-130	padR	-	-	K	-	-	-	Virulence activator alpha C-term
PKEHELCK_02854	2.71e-135	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
PKEHELCK_02855	6.11e-187	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
PKEHELCK_02856	3.66e-113	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
PKEHELCK_02857	4.02e-203	degV1	-	-	S	-	-	-	DegV family
PKEHELCK_02858	1.67e-79	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
PKEHELCK_02859	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
PKEHELCK_02861	2.76e-141	sip3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
PKEHELCK_02862	0.0	-	-	-	-	-	-	-	-
PKEHELCK_02864	2.23e-211	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
PKEHELCK_02865	2.99e-71	-	-	-	S	-	-	-	Cell surface protein
PKEHELCK_02866	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
PKEHELCK_02867	4.83e-64	-	-	-	-	-	-	-	-
PKEHELCK_02868	3.68e-77	-	-	-	-	-	-	-	-
PKEHELCK_02870	2.64e-210	-	-	-	-	-	-	-	-
PKEHELCK_02871	1.4e-95	-	-	-	K	-	-	-	Transcriptional regulator
PKEHELCK_02872	0.0	pepF2	-	-	E	-	-	-	Oligopeptidase F
PKEHELCK_02873	5.39e-222	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
PKEHELCK_02874	7.2e-61	-	-	-	S	-	-	-	Enterocin A Immunity
PKEHELCK_02875	8.34e-86	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
PKEHELCK_02876	5e-162	skfE	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
PKEHELCK_02877	2.66e-172	-	-	-	-	-	-	-	-
PKEHELCK_02878	9.38e-139	pncA	-	-	Q	-	-	-	Isochorismatase family
PKEHELCK_02879	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PKEHELCK_02880	0.0	nhaP2	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
PKEHELCK_02881	8.97e-253	yhhX	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
PKEHELCK_02882	9.51e-49	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
PKEHELCK_02883	2.39e-153	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
PKEHELCK_02884	6.87e-149	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
PKEHELCK_02885	1.48e-201	ccpB	-	-	K	-	-	-	lacI family
PKEHELCK_02886	2.2e-157	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
PKEHELCK_02887	9.88e-202	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PKEHELCK_02888	5.02e-228	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
PKEHELCK_02889	2.57e-128	-	-	-	C	-	-	-	Nitroreductase family
PKEHELCK_02890	6.04e-217	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
PKEHELCK_02891	5.29e-248	-	-	-	S	-	-	-	domain, Protein
PKEHELCK_02892	2.14e-183	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
PKEHELCK_02893	4.01e-236	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
PKEHELCK_02894	5.77e-76	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
PKEHELCK_02895	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
PKEHELCK_02896	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
PKEHELCK_02897	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
PKEHELCK_02898	2.66e-132	-	-	-	G	-	-	-	Glycogen debranching enzyme
PKEHELCK_02899	4.46e-63	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
PKEHELCK_02900	1.22e-210	yjdB	-	-	S	-	-	-	Domain of unknown function (DUF4767)
PKEHELCK_02901	1.96e-93	yisK	3.7.1.5, 4.1.1.68	-	Q	ko:K05921,ko:K16164	ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Fumarylacetoacetate (FAA) hydrolase family
PKEHELCK_02902	1.12e-74	yisK	3.7.1.5, 4.1.1.68	-	Q	ko:K05921,ko:K16164	ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Fumarylacetoacetate (FAA) hydrolase family
PKEHELCK_02903	1.04e-94	asp2	-	-	S	-	-	-	Asp23 family, cell envelope-related function
PKEHELCK_02904	1.1e-93	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
PKEHELCK_02905	5.74e-32	-	-	-	-	-	-	-	-
PKEHELCK_02906	1.37e-116	-	-	-	-	-	-	-	-
PKEHELCK_02907	1.81e-50	ydaS	-	-	S	-	-	-	Transglycosylase associated protein
PKEHELCK_02908	0.0	XK27_09800	-	-	I	-	-	-	Acyltransferase family
PKEHELCK_02909	2.09e-60	-	-	-	S	-	-	-	MORN repeat
PKEHELCK_02910	1.22e-85	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
PKEHELCK_02911	7.21e-152	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
PKEHELCK_02912	5.06e-297	yceJ	-	-	EGP	ko:K08221	-	ko00000,ko02000	transporter
PKEHELCK_02913	4.73e-206	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
PKEHELCK_02914	2.13e-167	-	-	-	L	-	-	-	Helix-turn-helix domain
PKEHELCK_02915	1.07e-74	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
PKEHELCK_02916	3.87e-141	XK27_07075	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
PKEHELCK_02917	3.92e-83	-	-	-	K	-	-	-	Helix-turn-helix domain
PKEHELCK_02918	1.26e-70	-	-	-	-	-	-	-	-
PKEHELCK_02919	3.36e-45	-	-	-	-	-	-	-	-
PKEHELCK_02920	4.87e-148	-	-	-	S	-	-	-	(CBS) domain
PKEHELCK_02921	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
PKEHELCK_02922	4.62e-225	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
PKEHELCK_02923	1.43e-129	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PKEHELCK_02924	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PKEHELCK_02925	0.0	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
PKEHELCK_02926	7.72e-57	yabO	-	-	J	-	-	-	S4 domain protein
PKEHELCK_02928	2.02e-83	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
PKEHELCK_02929	1.07e-103	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
PKEHELCK_02930	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PKEHELCK_02931	4.3e-124	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
PKEHELCK_02932	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PKEHELCK_02933	1.93e-209	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PKEHELCK_02934	5.33e-243	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PKEHELCK_02935	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
PKEHELCK_02936	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PKEHELCK_02937	1.74e-169	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
PKEHELCK_02938	1.05e-275	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
PKEHELCK_02939	4.85e-257	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PKEHELCK_02940	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PKEHELCK_02941	1.48e-128	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PKEHELCK_02942	6.92e-163	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
PKEHELCK_02943	1.06e-108	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
PKEHELCK_02944	1.17e-204	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
PKEHELCK_02945	7.46e-149	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
PKEHELCK_02946	2.68e-198	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
PKEHELCK_02947	7.29e-247	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
PKEHELCK_02948	0.0	ydaO	-	-	E	-	-	-	amino acid
PKEHELCK_02949	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PKEHELCK_02950	9.82e-55	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PKEHELCK_02951	2.38e-140	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
PKEHELCK_02952	7.34e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
PKEHELCK_02953	6.22e-43	cspP	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
PKEHELCK_02954	5.56e-245	mocA	-	-	S	-	-	-	Oxidoreductase
PKEHELCK_02955	5.62e-316	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
PKEHELCK_02957	3.93e-99	-	-	-	T	-	-	-	Universal stress protein family
PKEHELCK_02958	2.22e-313	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PKEHELCK_02959	1.93e-210	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
PKEHELCK_02961	7.62e-97	-	-	-	-	-	-	-	-
PKEHELCK_02962	2.9e-139	-	-	-	-	-	-	-	-
PKEHELCK_02963	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
PKEHELCK_02964	1.79e-272	pbpX	-	-	V	-	-	-	Beta-lactamase
PKEHELCK_02965	4.75e-267	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
PKEHELCK_02966	1.23e-200	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
PKEHELCK_02967	3.98e-169	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
PKEHELCK_02968	8.69e-276	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
PKEHELCK_02970	5.82e-89	-	-	-	-	-	-	-	-
PKEHELCK_02971	2.4e-186	-	-	-	S	ko:K06889	-	ko00000	Dienelactone hydrolase family
PKEHELCK_02972	9.89e-74	ytpP	-	-	CO	-	-	-	Thioredoxin
PKEHELCK_02973	6.69e-263	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
PKEHELCK_02974	3.89e-62	-	-	-	-	-	-	-	-
PKEHELCK_02975	2.57e-70	-	-	-	-	-	-	-	-
PKEHELCK_02976	6.94e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF2798)
PKEHELCK_02977	4.05e-98	-	-	-	-	-	-	-	-
PKEHELCK_02978	4.15e-78	-	-	-	-	-	-	-	-
PKEHELCK_02979	4.26e-250	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
PKEHELCK_02980	0.0	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Bacterial SH3 domain
PKEHELCK_02981	1.63e-95	-	-	-	G	ko:K02744	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
PKEHELCK_02982	3.82e-188	agaD	-	-	G	ko:K02747,ko:K02796,ko:K10986	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
PKEHELCK_02983	5.2e-185	-	-	-	G	ko:K02746,ko:K10985	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
PKEHELCK_02984	1.49e-112	-	2.7.1.191	-	K	ko:K02745,ko:K02794,ko:K10984	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
PKEHELCK_02985	5.87e-166	-	-	-	K	ko:K03710	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
PKEHELCK_02986	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PKEHELCK_02987	7.54e-115	yrxA	-	-	S	ko:K07105	-	ko00000	3H domain
PKEHELCK_02988	3.26e-262	-	-	-	EGP	-	-	-	Transmembrane secretion effector
PKEHELCK_02989	3.64e-293	-	-	-	S	-	-	-	Sterol carrier protein domain
PKEHELCK_02990	9.97e-269	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
PKEHELCK_02991	3.94e-49	XK27_01315	-	-	S	-	-	-	Protein of unknown function (DUF2829)
PKEHELCK_02992	1.62e-173	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
PKEHELCK_02993	2.26e-91	-	-	-	FG	-	-	-	Scavenger mRNA decapping enzyme C-term binding
PKEHELCK_02994	3.24e-132	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
PKEHELCK_02995	1.76e-143	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
PKEHELCK_02996	9.66e-17	-	-	-	S	-	-	-	Pentapeptide repeats (8 copies)
PKEHELCK_02997	4.68e-19	-	-	-	S	-	-	-	Pentapeptide repeats (8 copies)
PKEHELCK_02998	1.33e-185	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
PKEHELCK_02999	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
PKEHELCK_03000	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
PKEHELCK_03002	1.31e-29	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PKEHELCK_03003	1.88e-88	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
PKEHELCK_03004	2.98e-07	-	-	-	K	-	-	-	transcriptional regulator
PKEHELCK_03005	2.64e-272	-	-	-	S	-	-	-	membrane
PKEHELCK_03006	1.51e-105	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PKEHELCK_03007	0.0	-	-	-	S	-	-	-	Zinc finger, swim domain protein
PKEHELCK_03008	8.09e-146	-	-	-	GM	-	-	-	epimerase
PKEHELCK_03009	6.34e-90	-	-	-	S	-	-	-	Protein of unknown function (DUF1722)
PKEHELCK_03010	2.65e-93	spx2	-	-	P	ko:K16509	-	ko00000	ArsC family
PKEHELCK_03011	1.4e-137	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
PKEHELCK_03012	1.68e-176	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
PKEHELCK_03013	0.0	nox	-	-	P	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
PKEHELCK_03014	5.03e-119	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
PKEHELCK_03015	9.22e-127	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
PKEHELCK_03016	5.15e-277	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
PKEHELCK_03017	9.63e-306	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
PKEHELCK_03018	1.83e-140	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
PKEHELCK_03019	8.02e-152	plnU	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
PKEHELCK_03020	7.55e-143	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
PKEHELCK_03021	1.59e-145	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
PKEHELCK_03022	4.23e-64	axe	-	-	K	ko:K21498	-	ko00000,ko02048	Helix-turn-helix XRE-family like proteins
PKEHELCK_03023	0.0	-	-	-	L	-	-	-	DNA helicase
PKEHELCK_03024	5.87e-181	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
PKEHELCK_03025	1.36e-242	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
PKEHELCK_03026	9.01e-165	-	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
PKEHELCK_03027	0.0	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
PKEHELCK_03028	2.97e-41	-	-	-	-	-	-	-	-
PKEHELCK_03029	4.77e-236	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
PKEHELCK_03031	2.03e-52	-	-	-	S	ko:K09136	-	ko00000,ko03009	YcaO cyclodehydratase, ATP-ad Mg2+-binding
PKEHELCK_03032	7.19e-55	sagB	-	-	C	-	-	-	Nitroreductase family
PKEHELCK_03033	3.06e-05	-	-	-	S	-	-	-	Insulinase (Peptidase family M16)
PKEHELCK_03034	2.01e-128	-	-	-	V	ko:K01990,ko:K09695	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PKEHELCK_03035	1.32e-70	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-type multidrug transport system, permease component
PKEHELCK_03036	3.87e-21	-	-	-	S	-	-	-	FRG
PKEHELCK_03037	1.36e-132	tnpR	-	-	L	-	-	-	Resolvase, N terminal domain
PKEHELCK_03038	1e-218	-	-	-	L	-	-	-	Initiator Replication protein
PKEHELCK_03039	1.13e-71	-	-	-	-	-	-	-	-
PKEHELCK_03040	4.92e-138	-	-	-	L	-	-	-	Reverse transcriptase (RNA-dependent DNA polymerase)
PKEHELCK_03041	5.63e-177	-	-	-	K	-	-	-	Helix-turn-helix domain
PKEHELCK_03042	3.61e-15	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PKEHELCK_03043	0.000343	-	-	-	S	-	-	-	Protein of unknown function (DUF3923)
PKEHELCK_03044	3.03e-76	-	-	-	S	-	-	-	Bacterial toxin of type II toxin-antitoxin system, YafQ
PKEHELCK_03045	1.11e-59	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
PKEHELCK_03046	7.54e-130	-	-	-	L	-	-	-	Phage integrase family
PKEHELCK_03047	2.96e-47	tnp1216	-	-	L	ko:K07498	-	ko00000	DDE domain
PKEHELCK_03048	3.78e-248	-	-	-	U	ko:K07085	-	ko00000	Predicted Permease Membrane Region
PKEHELCK_03049	9.69e-301	aspD	4.1.1.12	-	E	ko:K09758	ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230	ko00000,ko00001,ko01000	Aminotransferase class I and II
PKEHELCK_03050	1.48e-81	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PKEHELCK_03051	8.44e-39	-	-	-	-	-	-	-	-
PKEHELCK_03052	6.93e-104	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
PKEHELCK_03053	4.38e-102	-	-	-	K	-	-	-	Transcriptional regulator
PKEHELCK_03054	4.97e-210	-	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Major Facilitator Superfamily
PKEHELCK_03055	6.05e-66	-	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Major Facilitator Superfamily
PKEHELCK_03056	1.27e-309	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PKEHELCK_03057	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
PKEHELCK_03058	1.02e-230	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
PKEHELCK_03059	4.8e-278	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
PKEHELCK_03060	1.93e-266	-	-	-	-	-	-	-	-
PKEHELCK_03061	6.11e-118	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
PKEHELCK_03062	2.27e-80	-	-	-	P	-	-	-	Rhodanese Homology Domain
PKEHELCK_03063	1.14e-09	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
PKEHELCK_03064	1.35e-70	-	-	-	L	-	-	-	Transposase
PKEHELCK_03065	2.58e-259	phnW	2.6.1.37	-	E	ko:K03430	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000,ko01007	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
PKEHELCK_03066	1.97e-187	phnX	3.11.1.1	-	E	ko:K05306	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the HAD-like hydrolase superfamily. PhnX family
PKEHELCK_03067	3.33e-184	phnE1	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PKEHELCK_03068	6.51e-178	phnE2	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter permease
PKEHELCK_03069	9.33e-177	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
PKEHELCK_03070	9.91e-242	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
PKEHELCK_03071	2.29e-165	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
PKEHELCK_03072	4.66e-131	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
PKEHELCK_03073	5.74e-108	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
PKEHELCK_03074	1.48e-248	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PKEHELCK_03075	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
PKEHELCK_03076	3.67e-154	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PKEHELCK_03077	7.81e-148	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PKEHELCK_03078	1.24e-296	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PKEHELCK_03079	2.96e-242	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
PKEHELCK_03080	9.87e-204	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PKEHELCK_03081	1.88e-251	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PKEHELCK_03082	5e-141	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
PKEHELCK_03083	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
PKEHELCK_03084	1.83e-175	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
PKEHELCK_03085	4.95e-250	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
PKEHELCK_03086	1.53e-244	ampC	-	-	V	-	-	-	Beta-lactamase
PKEHELCK_03087	2.1e-41	-	-	-	-	-	-	-	-
PKEHELCK_03088	5.02e-186	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
PKEHELCK_03090	4.51e-206	XK27_10395	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PKEHELCK_03091	4.34e-138	-	-	-	L	-	-	-	Resolvase, N terminal domain
PKEHELCK_03092	5.42e-146	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
PKEHELCK_03093	1.34e-231	-	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleotide reductase, small chain
PKEHELCK_03094	1.95e-220	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleotide reductase, small chain
PKEHELCK_03095	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PKEHELCK_03096	7.07e-106	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
PKEHELCK_03097	6.32e-08	-	3.3.1.1	-	H	ko:K01251	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	adenosylhomocysteinase activity
PKEHELCK_03098	4.28e-81	ypgQ	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
PKEHELCK_03099	7.72e-228	cps3B	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
PKEHELCK_03100	2.81e-282	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
PKEHELCK_03101	5.58e-260	cps3D	-	-	-	-	-	-	-
PKEHELCK_03102	3.98e-143	cps3E	-	-	-	-	-	-	-
PKEHELCK_03103	1.01e-208	cps3F	-	-	-	-	-	-	-
PKEHELCK_03104	7.45e-258	cps3H	-	-	-	-	-	-	-
PKEHELCK_03105	5.67e-257	cps3I	-	-	G	-	-	-	Acyltransferase family
PKEHELCK_03106	2.94e-190	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
PKEHELCK_03107	1.71e-304	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
PKEHELCK_03108	9.02e-78	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
PKEHELCK_03109	1.03e-77	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
PKEHELCK_03110	4.17e-55	-	-	-	K	-	-	-	prlF antitoxin for toxin YhaV_toxin
PKEHELCK_03111	1.87e-139	-	-	-	L	-	-	-	Integrase
PKEHELCK_03112	3.67e-41	-	-	-	-	-	-	-	-
PKEHELCK_03113	2.29e-225	-	-	-	L	-	-	-	Initiator Replication protein
PKEHELCK_03114	6.66e-115	-	-	-	-	-	-	-	-
PKEHELCK_03115	9.82e-111	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
PKEHELCK_03117	5.46e-118	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
PKEHELCK_03118	8.19e-49	-	-	-	L	-	-	-	Transposase DDE domain
PKEHELCK_03119	9e-47	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
PKEHELCK_03120	5.42e-24	-	-	-	M	-	-	-	Lysin motif
PKEHELCK_03122	2.32e-200	-	-	-	L	-	-	-	Initiator Replication protein
PKEHELCK_03123	4.32e-112	-	-	-	S	-	-	-	Protein of unknown function, DUF536
PKEHELCK_03124	7.06e-109	-	-	-	M	-	-	-	domain protein
PKEHELCK_03125	6.57e-274	-	-	-	O	-	-	-	AAA domain (Cdc48 subfamily)
PKEHELCK_03126	3.99e-193	-	-	-	-	-	-	-	-
PKEHELCK_03127	1.89e-84	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
PKEHELCK_03128	8.5e-55	-	-	-	K	-	-	-	Helix-turn-helix domain
PKEHELCK_03129	0.0	yeeA	-	-	V	-	-	-	Type II restriction enzyme, methylase subunits
PKEHELCK_03130	8.45e-37	-	-	-	-	-	-	-	-
PKEHELCK_03133	4.47e-75	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
PKEHELCK_03134	3.86e-109	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
PKEHELCK_03135	1.06e-124	gbuC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
PKEHELCK_03136	4.63e-143	gbuB	-	-	E	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
PKEHELCK_03137	2.97e-234	gbuA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
PKEHELCK_03138	4.91e-240	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
PKEHELCK_03139	4.73e-53	-	-	-	M	-	-	-	LysM domain protein
PKEHELCK_03140	1.15e-261	butB	1.1.1.14, 1.1.1.264, 1.1.1.303, 1.1.1.4	-	C	ko:K00004,ko:K00008,ko:K00098	ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
PKEHELCK_03141	1.1e-131	-	-	-	-	-	-	-	-
PKEHELCK_03142	3.13e-66	-	-	-	S	-	-	-	Cag pathogenicity island, type IV secretory system
PKEHELCK_03143	5.39e-71	-	-	-	-	-	-	-	-
PKEHELCK_03144	2.59e-151	-	-	-	-	-	-	-	-
PKEHELCK_03145	0.0	-	-	-	U	-	-	-	AAA-like domain
PKEHELCK_03146	6.16e-316	-	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
PKEHELCK_03147	7.1e-273	-	-	-	M	-	-	-	CHAP domain
PKEHELCK_03148	1.85e-119	-	-	-	-	-	-	-	-
PKEHELCK_03149	2.27e-82	-	-	-	CO	-	-	-	COG0526, thiol-disulfide isomerase and thioredoxins
PKEHELCK_03150	1.23e-100	-	-	-	-	-	-	-	-
PKEHELCK_03152	0.0	traK	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	TraM recognition site of TraD and TraG
PKEHELCK_03153	1.89e-82	-	-	-	-	-	-	-	-
PKEHELCK_03154	1.26e-244	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
PKEHELCK_03155	7.1e-118	ydhK	-	-	M	-	-	-	Protein of unknown function (DUF1541)
PKEHELCK_03157	7.73e-178	cylB	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
PKEHELCK_03158	3.99e-198	cylA	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
PKEHELCK_03159	3.46e-130	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
PKEHELCK_03160	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
PKEHELCK_03161	3.82e-39	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
PKEHELCK_03162	6.59e-69	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
PKEHELCK_03163	6.96e-20	-	-	-	S	-	-	-	Transglycosylase associated protein
PKEHELCK_03164	2.48e-48	-	-	-	K	ko:K16137,ko:K18939	-	ko00000,ko00002,ko03000	Bacterial regulatory proteins, tetR family
PKEHELCK_03165	2.25e-45	-	-	-	K	ko:K16137,ko:K18939	-	ko00000,ko00002,ko03000	Bacterial regulatory proteins, tetR family
PKEHELCK_03166	7.91e-78	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
PKEHELCK_03167	1.46e-07	-	-	-	D	-	-	-	Di-iron-containing protein involved in the repair of iron-sulfur clusters
PKEHELCK_03168	2.26e-130	-	-	-	L	-	-	-	Resolvase, N terminal domain
PKEHELCK_03169	2.04e-158	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
PKEHELCK_03170	1.49e-63	-	-	-	-	-	-	-	-
PKEHELCK_03171	0.0	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
PKEHELCK_03172	2.92e-235	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
PKEHELCK_03173	2.87e-56	-	-	-	-	-	-	-	-
PKEHELCK_03174	3.35e-75	-	-	-	-	-	-	-	-
PKEHELCK_03175	6.86e-311	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PKEHELCK_03176	1.96e-167	yidA	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
PKEHELCK_03177	2.42e-65	-	-	-	-	-	-	-	-
PKEHELCK_03178	1.33e-165	rrp2	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
PKEHELCK_03179	2.78e-142	hpk2	-	-	T	-	-	-	Histidine kinase
PKEHELCK_03180	2.83e-108	hpk2	-	-	T	-	-	-	Histidine kinase
PKEHELCK_03181	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
PKEHELCK_03182	1.51e-85	-	-	-	KOT	ko:K07813	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01002	May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
PKEHELCK_03183	9.62e-19	-	-	-	-	-	-	-	-
PKEHELCK_03184	2.18e-211	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
PKEHELCK_03185	7.42e-174	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
PKEHELCK_03186	1.32e-101	nrp	-	-	K	ko:K16509	-	ko00000	ArsC family
PKEHELCK_03187	0.0	katA	1.11.1.6	-	C	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	Belongs to the catalase family
PKEHELCK_03188	1.96e-21	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
PKEHELCK_03189	1.06e-16	-	-	-	-	-	-	-	-
PKEHELCK_03190	2.1e-116	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
PKEHELCK_03191	4.92e-91	-	-	-	S	-	-	-	Pyrimidine dimer DNA glycosylase
PKEHELCK_03192	1.96e-137	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
PKEHELCK_03193	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
PKEHELCK_03194	3.54e-293	vex3	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
PKEHELCK_03195	4.87e-156	vex2	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
PKEHELCK_03196	1.87e-170	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
PKEHELCK_03197	9.19e-155	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
PKEHELCK_03198	1.93e-73	-	-	-	M	-	-	-	Lysin motif
PKEHELCK_03199	1.43e-82	-	-	-	M	-	-	-	LysM domain protein
PKEHELCK_03200	9.04e-78	-	-	-	S	-	-	-	Bacterial toxin of type II toxin-antitoxin system, YafQ
PKEHELCK_03201	1.11e-59	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
PKEHELCK_03202	4.4e-138	-	-	-	L	-	-	-	Integrase
PKEHELCK_03203	2.43e-59	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
PKEHELCK_03204	3.03e-49	-	-	-	K	-	-	-	sequence-specific DNA binding
PKEHELCK_03205	1.5e-68	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
PKEHELCK_03206	3.95e-231	-	-	-	U	-	-	-	Relaxase/Mobilisation nuclease domain
PKEHELCK_03207	9.81e-73	repA	-	-	S	-	-	-	Replication initiator protein A
PKEHELCK_03208	4.59e-58	-	-	-	-	-	-	-	-
PKEHELCK_03209	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
PKEHELCK_03210	7.27e-31	-	-	-	-	-	-	-	-
PKEHELCK_03211	1.47e-55	-	-	-	-	-	-	-	-
PKEHELCK_03212	4.42e-77	-	-	-	Q	-	-	-	Methyltransferase
PKEHELCK_03213	4.55e-174	repA	-	-	S	-	-	-	Replication initiator protein A
PKEHELCK_03215	8.87e-173	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
PKEHELCK_03216	8.6e-83	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PKEHELCK_03217	0.0	ybeC	-	-	E	-	-	-	amino acid
PKEHELCK_03218	0.0	-	-	-	U	-	-	-	AAA-like domain
PKEHELCK_03219	4.4e-316	-	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
PKEHELCK_03220	2.28e-271	-	-	-	M	-	-	-	CHAP domain
PKEHELCK_03221	2.15e-118	-	-	-	-	-	-	-	-
PKEHELCK_03222	2.08e-82	-	-	-	CO	-	-	-	COG0526, thiol-disulfide isomerase and thioredoxins
PKEHELCK_03223	8.05e-106	-	-	-	-	-	-	-	-
PKEHELCK_03224	0.0	traK	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	TraM recognition site of TraD and TraG
PKEHELCK_03225	8.57e-80	-	-	-	-	-	-	-	-
PKEHELCK_03226	0.0	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
PKEHELCK_03227	4.53e-45	-	-	-	-	-	-	-	-
PKEHELCK_03228	6.19e-237	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
PKEHELCK_03229	3.59e-26	-	-	-	-	-	-	-	-
PKEHELCK_03230	4.55e-75	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
PKEHELCK_03231	1.98e-50	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
PKEHELCK_03232	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
PKEHELCK_03233	1.28e-98	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Transcriptional regulator
PKEHELCK_03234	2.33e-56	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
PKEHELCK_03235	1.31e-139	yoaZ	-	-	S	-	-	-	intracellular protease amidase
PKEHELCK_03236	1.04e-59	-	-	-	S	-	-	-	Protein of unknown function (DUF3781)
PKEHELCK_03237	1.29e-278	-	-	-	S	-	-	-	Membrane
PKEHELCK_03238	5.98e-85	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
PKEHELCK_03239	4.83e-31	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
PKEHELCK_03240	5.61e-54	pcaC	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
PKEHELCK_03241	5.15e-16	-	-	-	-	-	-	-	-
PKEHELCK_03242	2.13e-66	-	-	-	-	-	-	-	-
PKEHELCK_03243	5.39e-26	-	-	-	L	-	-	-	Integrase
PKEHELCK_03244	3.16e-59	-	-	-	T	ko:K07172	-	ko00000,ko02048	Antidote-toxin recognition MazE, bacterial antitoxin
PKEHELCK_03245	3.2e-76	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
PKEHELCK_03246	6.56e-233	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
PKEHELCK_03247	3.47e-61	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
PKEHELCK_03248	3.8e-224	-	-	-	L	-	-	-	Initiator Replication protein
PKEHELCK_03249	6.78e-42	-	-	-	-	-	-	-	-
PKEHELCK_03250	2.77e-79	-	-	-	L	-	-	-	Integrase
PKEHELCK_03251	2.23e-260	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
PKEHELCK_03252	5.31e-66	-	-	-	K	-	-	-	Helix-turn-helix domain
PKEHELCK_03253	2.06e-81	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
PKEHELCK_03254	3.8e-76	-	-	-	-	-	-	-	-
PKEHELCK_03255	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
PKEHELCK_03256	1.67e-135	-	-	-	K	-	-	-	transcriptional regulator
PKEHELCK_03257	1.01e-170	spoVK	-	-	O	ko:K06413	-	ko00000	ATPase family associated with various cellular activities (AAA)
PKEHELCK_03259	9.16e-61	-	-	-	L	-	-	-	Helix-turn-helix domain
PKEHELCK_03260	1.51e-22	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
PKEHELCK_03261	8.56e-38	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
PKEHELCK_03262	6.67e-30	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
PKEHELCK_03266	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
PKEHELCK_03267	1.15e-35	-	-	-	-	-	-	-	-
PKEHELCK_03268	4.6e-25	-	-	-	-	-	-	-	-
PKEHELCK_03269	9.71e-70	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
PKEHELCK_03270	2.75e-76	-	-	-	L	-	-	-	manually curated
PKEHELCK_03272	2.5e-236	-	-	-	S	-	-	-	nuclear-transcribed mRNA catabolic process, no-go decay
PKEHELCK_03273	4.36e-148	-	-	-	EGP	-	-	-	Transmembrane secretion effector
PKEHELCK_03274	3.31e-90	thiF	2.7.7.73	-	H	ko:K03148	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	ThiF family
PKEHELCK_03276	6.07e-301	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PKEHELCK_03277	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
PKEHELCK_03278	1.9e-148	-	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
PKEHELCK_03279	2.99e-61	-	-	-	S	ko:K06915	-	ko00000	Domain of unknown function DUF87
PKEHELCK_03280	6.38e-55	-	-	-	S	-	-	-	SIR2-like domain
PKEHELCK_03281	5.26e-245	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
PKEHELCK_03282	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
PKEHELCK_03283	1.07e-110	cps3A	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
PKEHELCK_03285	6.17e-71	-	-	-	S	-	-	-	SMI1-KNR4 cell-wall
PKEHELCK_03286	8.99e-172	astA	2.8.2.22	-	M	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
PKEHELCK_03287	5.99e-224	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
PKEHELCK_03288	3.72e-145	cysC	2.7.1.25	-	F	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
PKEHELCK_03289	1.75e-130	sat	2.7.7.4	-	H	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
PKEHELCK_03290	9.07e-64	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
PKEHELCK_03291	7.85e-29	-	-	-	-	-	-	-	-
PKEHELCK_03292	4.36e-48	-	-	-	L	-	-	-	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PKEHELCK_03293	7.76e-85	-	-	-	D	-	-	-	AAA domain
PKEHELCK_03294	8.83e-06	-	-	-	-	-	-	-	-
PKEHELCK_03295	1.82e-56	-	-	-	S	-	-	-	AAA domain
PKEHELCK_03298	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
PKEHELCK_03299	8.36e-90	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
PKEHELCK_03300	2e-111	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
PKEHELCK_03302	7.55e-74	is18	-	-	L	-	-	-	Integrase core domain
PKEHELCK_03303	4.13e-51	-	-	-	L	ko:K07483	-	ko00000	Transposase and inactivated derivatives
PKEHELCK_03304	1.9e-47	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
PKEHELCK_03305	9.2e-46	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
PKEHELCK_03306	7.57e-114	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
PKEHELCK_03307	2.38e-32	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
PKEHELCK_03308	1.07e-230	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
PKEHELCK_03309	2.4e-47	-	-	-	-	-	-	-	-
PKEHELCK_03310	8.88e-45	-	-	-	-	-	-	-	-
PKEHELCK_03311	1.66e-62	-	-	-	KLT	-	-	-	serine threonine protein kinase
PKEHELCK_03313	1.77e-145	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
PKEHELCK_03314	2.31e-132	thgA3	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
PKEHELCK_03315	8.9e-72	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PKEHELCK_03316	1.05e-73	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
PKEHELCK_03317	1.18e-123	-	-	-	L	-	-	-	Resolvase, N terminal domain
PKEHELCK_03319	3.5e-51	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	PFAM Cobyrinic acid a,c-diamide synthase
PKEHELCK_03321	8.96e-23	-	-	-	-	-	-	-	-
PKEHELCK_03323	8.68e-47	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	TraM recognition site of TraD and TraG
PKEHELCK_03325	2.59e-45	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	TraM recognition site of TraD and TraG
PKEHELCK_03326	5.6e-292	-	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
PKEHELCK_03327	2.65e-133	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
PKEHELCK_03328	4.9e-39	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
PKEHELCK_03330	4.75e-107	repE	-	-	K	-	-	-	Primase C terminal 1 (PriCT-1)
PKEHELCK_03331	2.83e-26	-	-	-	-	-	-	-	-
PKEHELCK_03333	3.05e-174	-	-	-	D	-	-	-	Cellulose biosynthesis protein BcsQ
PKEHELCK_03334	0.0	-	-	-	S	-	-	-	MucBP domain
PKEHELCK_03336	5.53e-105	-	-	-	-	-	-	-	-
PKEHELCK_03337	8.94e-70	-	-	-	-	-	-	-	-
PKEHELCK_03338	4.45e-66	-	-	-	S	-	-	-	Cag pathogenicity island, type IV secretory system
PKEHELCK_03339	3.28e-133	-	-	-	-	-	-	-	-
PKEHELCK_03340	8.66e-173	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
PKEHELCK_03341	8.48e-88	gcsH1	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Glycine cleavage H-protein
PKEHELCK_03342	6.1e-227	-	-	-	-	-	-	-	-
PKEHELCK_03343	1.91e-47	-	-	-	-	-	-	-	-
PKEHELCK_03344	9.87e-121	-	-	-	D	-	-	-	Cellulose biosynthesis protein BcsQ
PKEHELCK_03345	6.8e-35	-	-	-	-	-	-	-	-
PKEHELCK_03346	5.8e-58	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
PKEHELCK_03347	2.59e-19	-	-	-	-	-	-	-	-
PKEHELCK_03348	1.93e-31	plnF	-	-	-	-	-	-	-
PKEHELCK_03352	1.17e-54	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
PKEHELCK_03353	2.95e-58	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
PKEHELCK_03354	1.23e-151	-	-	-	K	-	-	-	Transcriptional regulator
PKEHELCK_03355	7.6e-124	-	-	-	-	-	-	-	-
PKEHELCK_03356	4.03e-85	-	-	-	-	-	-	-	-
PKEHELCK_03357	1.96e-224	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
PKEHELCK_03358	2.69e-226	-	-	-	L	ko:K07482	-	ko00000	Integrase core domain
PKEHELCK_03359	2.13e-141	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
PKEHELCK_03360	4.41e-79	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
PKEHELCK_03361	1.13e-163	is18	-	-	L	-	-	-	Integrase core domain
PKEHELCK_03363	4.92e-86	-	-	-	D	-	-	-	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
PKEHELCK_03364	2.09e-40	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
PKEHELCK_03365	3.33e-89	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
PKEHELCK_03367	2.48e-52	-	-	-	L	ko:K07483	-	ko00000	Transposase and inactivated derivatives