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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
ENCJOHLD_00002	6.87e-33	-	-	-	K	-	-	-	sequence-specific DNA binding
ENCJOHLD_00003	5.69e-185	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
ENCJOHLD_00004	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
ENCJOHLD_00005	3.32e-210	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
ENCJOHLD_00006	1.23e-58	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
ENCJOHLD_00007	1.07e-241	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
ENCJOHLD_00008	1.92e-264	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
ENCJOHLD_00009	8.69e-230	citR	-	-	K	-	-	-	sugar-binding domain protein
ENCJOHLD_00010	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
ENCJOHLD_00011	1.07e-213	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
ENCJOHLD_00012	1.18e-66	-	-	-	-	-	-	-	-
ENCJOHLD_00013	5.19e-223	mntA	-	-	P	ko:K19975,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
ENCJOHLD_00014	3.54e-180	mtsB	-	-	U	ko:K19972,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
ENCJOHLD_00015	2.04e-170	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
ENCJOHLD_00016	5.24e-195	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
ENCJOHLD_00017	5.75e-164	-	-	-	K	-	-	-	Helix-turn-helix domain
ENCJOHLD_00018	1.66e-53	-	-	-	K	-	-	-	Helix-turn-helix domain
ENCJOHLD_00019	5.21e-226	ttdA	4.2.1.32	-	C	ko:K03779	ko00630,map00630	ko00000,ko00001,ko01000	Fumarate hydratase (Fumerase)
ENCJOHLD_00020	2.01e-147	-	4.2.1.2, 4.2.1.32	-	C	ko:K01676,ko:K03780	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible hydration of fumarate to (S)- malate
ENCJOHLD_00021	6.15e-69	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
ENCJOHLD_00022	3.92e-279	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
ENCJOHLD_00023	1.23e-251	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ENCJOHLD_00024	7.76e-234	aroF	2.5.1.54	-	E	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	DAHP synthetase I family
ENCJOHLD_00025	6.73e-211	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ENCJOHLD_00026	0.0	tkt2	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ENCJOHLD_00027	1.83e-259	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
ENCJOHLD_00028	5.79e-234	-	-	-	S	-	-	-	Membrane
ENCJOHLD_00029	8.51e-210	yitS	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
ENCJOHLD_00030	8.98e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
ENCJOHLD_00031	4.58e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ENCJOHLD_00032	3.06e-194	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
ENCJOHLD_00033	2.49e-186	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ENCJOHLD_00034	3.47e-212	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ENCJOHLD_00035	3.42e-198	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ENCJOHLD_00036	1.07e-264	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
ENCJOHLD_00037	3.19e-194	-	-	-	S	-	-	-	FMN_bind
ENCJOHLD_00038	0.0	ndh	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
ENCJOHLD_00039	5.37e-112	-	-	-	S	-	-	-	NusG domain II
ENCJOHLD_00040	1.41e-122	hepA	2.5.1.30	-	S	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase component I
ENCJOHLD_00041	1.02e-233	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
ENCJOHLD_00042	7.76e-81	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
ENCJOHLD_00043	2.19e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ENCJOHLD_00044	7.71e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ENCJOHLD_00045	9.65e-79	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ENCJOHLD_00046	9.87e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ENCJOHLD_00047	5.28e-160	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
ENCJOHLD_00048	5.95e-300	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
ENCJOHLD_00049	1.32e-91	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
ENCJOHLD_00050	8.44e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
ENCJOHLD_00051	5.32e-109	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ENCJOHLD_00052	1.75e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ENCJOHLD_00053	2.14e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ENCJOHLD_00054	4.99e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ENCJOHLD_00055	3.53e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ENCJOHLD_00056	4.1e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ENCJOHLD_00057	2.98e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ENCJOHLD_00058	1.96e-54	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ENCJOHLD_00059	1.11e-33	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
ENCJOHLD_00060	8.29e-100	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ENCJOHLD_00061	5.46e-152	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ENCJOHLD_00062	3.59e-69	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ENCJOHLD_00063	1.85e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ENCJOHLD_00064	6.61e-193	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ENCJOHLD_00065	2.27e-59	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
ENCJOHLD_00066	9.83e-141	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
ENCJOHLD_00067	4.34e-145	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ENCJOHLD_00068	4.46e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
ENCJOHLD_00069	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ENCJOHLD_00070	1.19e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
ENCJOHLD_00071	4.19e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ENCJOHLD_00072	1e-147	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
ENCJOHLD_00073	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ENCJOHLD_00074	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ENCJOHLD_00075	1.16e-140	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
ENCJOHLD_00076	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
ENCJOHLD_00077	9.78e-102	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
ENCJOHLD_00085	1.62e-294	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ENCJOHLD_00086	1.11e-148	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
ENCJOHLD_00087	1.29e-153	dacB	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
ENCJOHLD_00088	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
ENCJOHLD_00089	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
ENCJOHLD_00090	1.7e-118	-	-	-	K	-	-	-	Transcriptional regulator
ENCJOHLD_00091	3.03e-129	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
ENCJOHLD_00092	3.88e-198	-	-	-	I	-	-	-	alpha/beta hydrolase fold
ENCJOHLD_00093	2.05e-153	-	-	-	I	-	-	-	phosphatase
ENCJOHLD_00094	2.34e-242	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
ENCJOHLD_00095	7.76e-100	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
ENCJOHLD_00096	4.6e-169	-	-	-	S	-	-	-	Putative threonine/serine exporter
ENCJOHLD_00097	1.78e-42	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
ENCJOHLD_00098	2.94e-155	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
ENCJOHLD_00099	1.36e-77	-	-	-	-	-	-	-	-
ENCJOHLD_00100	6.41e-111	-	-	-	K	-	-	-	MerR HTH family regulatory protein
ENCJOHLD_00101	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
ENCJOHLD_00102	4.51e-151	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
ENCJOHLD_00103	1.46e-170	-	-	-	-	-	-	-	-
ENCJOHLD_00104	1.75e-47	-	-	-	K	-	-	-	MerR HTH family regulatory protein
ENCJOHLD_00105	1.26e-16	azlC	-	-	E	-	-	-	branched-chain amino acid
ENCJOHLD_00106	9.88e-124	azlC	-	-	E	-	-	-	branched-chain amino acid
ENCJOHLD_00107	2.41e-66	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
ENCJOHLD_00108	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
ENCJOHLD_00109	1.2e-281	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
ENCJOHLD_00110	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ENCJOHLD_00111	0.0	xylP2	-	-	G	-	-	-	symporter
ENCJOHLD_00112	7.32e-247	-	-	-	I	-	-	-	alpha/beta hydrolase fold
ENCJOHLD_00113	3.33e-64	-	-	-	-	-	-	-	-
ENCJOHLD_00114	1.5e-156	gpm5	-	-	G	-	-	-	Phosphoglycerate mutase family
ENCJOHLD_00115	4.77e-130	-	-	-	K	-	-	-	FR47-like protein
ENCJOHLD_00116	8.44e-163	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
ENCJOHLD_00117	3.28e-278	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
ENCJOHLD_00118	1.12e-243	-	-	-	-	-	-	-	-
ENCJOHLD_00119	2.91e-179	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
ENCJOHLD_00120	5.06e-68	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
ENCJOHLD_00121	1.36e-208	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
ENCJOHLD_00122	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
ENCJOHLD_00123	4.95e-44	-	-	-	L	-	-	-	leucine-zipper of insertion element IS481
ENCJOHLD_00124	5.44e-56	-	-	-	-	-	-	-	-
ENCJOHLD_00125	1.54e-289	-	-	-	L	-	-	-	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ENCJOHLD_00126	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
ENCJOHLD_00127	3.39e-255	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
ENCJOHLD_00128	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
ENCJOHLD_00129	4.71e-149	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ENCJOHLD_00130	4.3e-106	-	-	-	K	-	-	-	Transcriptional regulator
ENCJOHLD_00132	0.0	-	-	-	C	-	-	-	FMN_bind
ENCJOHLD_00133	1.32e-218	-	-	-	K	-	-	-	Transcriptional regulator
ENCJOHLD_00134	1.88e-124	-	-	-	K	-	-	-	Helix-turn-helix domain
ENCJOHLD_00135	1.06e-179	-	-	-	K	-	-	-	sequence-specific DNA binding
ENCJOHLD_00136	2.87e-112	-	-	-	S	-	-	-	AAA domain
ENCJOHLD_00137	1.42e-08	-	-	-	-	-	-	-	-
ENCJOHLD_00138	0.0	-	-	-	M	-	-	-	MucBP domain
ENCJOHLD_00139	2.76e-110	XK27_09665	-	-	G	ko:K15640	-	ko00000	Phosphoglycerate mutase family
ENCJOHLD_00140	2.4e-27	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
ENCJOHLD_00141	9.94e-211	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
ENCJOHLD_00142	5.6e-56	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
ENCJOHLD_00143	1.95e-66	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
ENCJOHLD_00144	5.79e-293	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	PFAM N-6 DNA methylase
ENCJOHLD_00145	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
ENCJOHLD_00146	2.88e-48	-	-	-	V	-	-	-	type I restriction modification DNA specificity domain
ENCJOHLD_00147	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
ENCJOHLD_00148	3.63e-130	-	-	-	G	-	-	-	Glycogen debranching enzyme
ENCJOHLD_00149	5.21e-62	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
ENCJOHLD_00150	4.25e-211	yjdB	-	-	S	-	-	-	Domain of unknown function (DUF4767)
ENCJOHLD_00151	1.59e-189	yisK	3.7.1.5, 4.1.1.68	-	Q	ko:K05921,ko:K16164	ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Fumarylacetoacetate (FAA) hydrolase family
ENCJOHLD_00152	1.04e-94	asp2	-	-	S	-	-	-	Asp23 family, cell envelope-related function
ENCJOHLD_00153	1.1e-93	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
ENCJOHLD_00154	5.74e-32	-	-	-	-	-	-	-	-
ENCJOHLD_00155	1.95e-116	-	-	-	-	-	-	-	-
ENCJOHLD_00156	1.81e-50	ydaS	-	-	S	-	-	-	Transglycosylase associated protein
ENCJOHLD_00157	0.0	XK27_09800	-	-	I	-	-	-	Acyltransferase family
ENCJOHLD_00158	3.61e-61	-	-	-	S	-	-	-	MORN repeat
ENCJOHLD_00159	7.04e-299	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
ENCJOHLD_00160	4.73e-302	yceJ	-	-	EGP	ko:K08221	-	ko00000,ko02000	transporter
ENCJOHLD_00161	1.85e-75	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
ENCJOHLD_00162	2.01e-149	XK27_07075	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
ENCJOHLD_00163	0.0	-	-	-	L	-	-	-	AAA domain
ENCJOHLD_00164	1.37e-83	-	-	-	K	-	-	-	Helix-turn-helix domain
ENCJOHLD_00165	1.08e-71	-	-	-	-	-	-	-	-
ENCJOHLD_00166	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
ENCJOHLD_00167	1.22e-227	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
ENCJOHLD_00168	5.95e-211	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
ENCJOHLD_00169	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
ENCJOHLD_00170	1.06e-141	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
ENCJOHLD_00171	1.39e-225	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
ENCJOHLD_00172	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
ENCJOHLD_00173	2.07e-161	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
ENCJOHLD_00174	2.61e-163	pgm3	-	-	G	-	-	-	Phosphoglycerate mutase family
ENCJOHLD_00175	1.61e-36	-	-	-	-	-	-	-	-
ENCJOHLD_00176	3.5e-64	sugE	-	-	U	ko:K11741	-	ko00000,ko02000	Multidrug resistance protein
ENCJOHLD_00177	1.13e-102	rppH3	-	-	F	-	-	-	NUDIX domain
ENCJOHLD_00178	5.95e-300	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ENCJOHLD_00179	3.65e-128	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
ENCJOHLD_00180	2.93e-109	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
ENCJOHLD_00181	3.22e-269	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
ENCJOHLD_00182	3.08e-93	-	-	-	K	-	-	-	MarR family
ENCJOHLD_00183	8.87e-191	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
ENCJOHLD_00184	3.1e-96	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
ENCJOHLD_00185	0.0	steT	-	-	E	ko:K03294	-	ko00000	amino acid
ENCJOHLD_00186	1.57e-182	-	3.5.1.105	-	G	ko:K03478	-	ko00000,ko01000	YdjC-like protein
ENCJOHLD_00187	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
ENCJOHLD_00188	7.77e-197	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
ENCJOHLD_00189	8.22e-107	-	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
ENCJOHLD_00190	1.27e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
ENCJOHLD_00191	3.14e-140	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
ENCJOHLD_00192	3.39e-190	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
ENCJOHLD_00193	2.3e-172	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
ENCJOHLD_00195	1.23e-52	-	-	-	-	-	-	-	-
ENCJOHLD_00196	1.03e-217	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ENCJOHLD_00197	3.21e-268	aspC	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
ENCJOHLD_00198	6.94e-146	gph1	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD hydrolase, family IA, variant
ENCJOHLD_00199	1.01e-188	-	-	-	-	-	-	-	-
ENCJOHLD_00200	8.84e-18	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
ENCJOHLD_00201	2.02e-106	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
ENCJOHLD_00202	7.32e-136	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
ENCJOHLD_00203	1.48e-27	-	-	-	-	-	-	-	-
ENCJOHLD_00204	7.48e-96	-	-	-	F	-	-	-	Nudix hydrolase
ENCJOHLD_00205	5.24e-191	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
ENCJOHLD_00206	6.12e-115	-	-	-	-	-	-	-	-
ENCJOHLD_00207	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
ENCJOHLD_00208	1.21e-63	-	-	-	-	-	-	-	-
ENCJOHLD_00209	1.55e-89	-	-	-	O	-	-	-	OsmC-like protein
ENCJOHLD_00210	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
ENCJOHLD_00211	0.0	oatA	-	-	I	-	-	-	Acyltransferase
ENCJOHLD_00212	1.23e-229	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
ENCJOHLD_00213	6.37e-232	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
ENCJOHLD_00214	0.0	pox2	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
ENCJOHLD_00215	3.3e-199	ribC1	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
ENCJOHLD_00216	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
ENCJOHLD_00217	1.79e-287	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
ENCJOHLD_00218	1.36e-27	-	-	-	-	-	-	-	-
ENCJOHLD_00219	6.16e-107	-	-	-	K	-	-	-	Transcriptional regulator
ENCJOHLD_00220	6.68e-197	licD	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
ENCJOHLD_00221	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
ENCJOHLD_00222	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ENCJOHLD_00223	4.45e-226	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
ENCJOHLD_00224	1.06e-314	-	-	-	EGP	-	-	-	Major Facilitator
ENCJOHLD_00225	2.08e-117	-	-	-	V	-	-	-	VanZ like family
ENCJOHLD_00226	3.88e-46	-	-	-	-	-	-	-	-
ENCJOHLD_00227	5.45e-94	spx1	-	-	P	ko:K16509	-	ko00000	ArsC family
ENCJOHLD_00229	5.03e-183	-	-	-	-	-	-	-	-
ENCJOHLD_00230	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ENCJOHLD_00231	1.15e-41	-	-	-	G	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
ENCJOHLD_00232	7.34e-180	-	-	-	EGP	-	-	-	Transmembrane secretion effector
ENCJOHLD_00233	7.06e-169	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
ENCJOHLD_00234	2.05e-94	-	-	-	-	-	-	-	-
ENCJOHLD_00235	3.38e-70	-	-	-	-	-	-	-	-
ENCJOHLD_00236	1.46e-263	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
ENCJOHLD_00237	7.01e-135	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
ENCJOHLD_00238	3.27e-189	-	3.1.3.23	-	S	ko:K07757	-	ko00000,ko01000	Sucrose-6F-phosphate phosphohydrolase
ENCJOHLD_00239	3.15e-158	-	-	-	T	-	-	-	EAL domain
ENCJOHLD_00240	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
ENCJOHLD_00241	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ENCJOHLD_00242	2.18e-182	ybbR	-	-	S	-	-	-	YbbR-like protein
ENCJOHLD_00243	8.33e-192	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ENCJOHLD_00244	2.31e-155	-	-	-	S	-	-	-	Protein of unknown function (DUF1361)
ENCJOHLD_00245	3.07e-119	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
ENCJOHLD_00246	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
ENCJOHLD_00247	6.24e-214	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
ENCJOHLD_00248	3.09e-213	ysjB	-	-	S	ko:K03810	-	ko00000	Oxidoreductase family, NAD-binding Rossmann fold
ENCJOHLD_00249	1.46e-197	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
ENCJOHLD_00250	2.41e-129	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
ENCJOHLD_00251	2.52e-114	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
ENCJOHLD_00252	1.29e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
ENCJOHLD_00253	1.23e-227	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
ENCJOHLD_00254	5.71e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ENCJOHLD_00255	1.98e-199	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
ENCJOHLD_00256	7.98e-137	-	-	-	-	-	-	-	-
ENCJOHLD_00257	9.36e-171	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
ENCJOHLD_00258	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
ENCJOHLD_00259	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
ENCJOHLD_00260	2.4e-107	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
ENCJOHLD_00261	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
ENCJOHLD_00262	6.62e-180	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
ENCJOHLD_00263	1.76e-43	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
ENCJOHLD_00264	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
ENCJOHLD_00265	5.11e-171	-	-	-	-	-	-	-	-
ENCJOHLD_00266	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
ENCJOHLD_00267	7.15e-179	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
ENCJOHLD_00268	1.31e-285	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
ENCJOHLD_00269	2.02e-245	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
ENCJOHLD_00270	5.75e-242	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
ENCJOHLD_00271	1.14e-311	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	Sigma-54 factor, core binding domain
ENCJOHLD_00273	5.11e-133	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
ENCJOHLD_00274	8.95e-225	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ENCJOHLD_00275	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
ENCJOHLD_00276	1.21e-215	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
ENCJOHLD_00277	4.56e-243	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
ENCJOHLD_00278	1.71e-207	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
ENCJOHLD_00279	6.07e-114	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
ENCJOHLD_00280	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
ENCJOHLD_00281	7.5e-302	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
ENCJOHLD_00282	2.21e-113	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
ENCJOHLD_00283	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
ENCJOHLD_00284	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
ENCJOHLD_00285	3.85e-151	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
ENCJOHLD_00286	5.33e-268	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
ENCJOHLD_00287	4.63e-135	aad	3.4.13.22	-	E	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
ENCJOHLD_00288	0.0	nox2	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
ENCJOHLD_00289	5.9e-170	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
ENCJOHLD_00290	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
ENCJOHLD_00291	7.54e-99	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
ENCJOHLD_00292	4.31e-141	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
ENCJOHLD_00293	8.65e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
ENCJOHLD_00294	7.91e-172	-	-	-	T	-	-	-	diguanylate cyclase activity
ENCJOHLD_00295	0.0	-	-	-	S	-	-	-	Bacterial cellulose synthase subunit
ENCJOHLD_00296	3.19e-276	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
ENCJOHLD_00297	9.69e-256	-	-	-	S	-	-	-	Protein conserved in bacteria
ENCJOHLD_00298	4.95e-310	-	-	-	-	-	-	-	-
ENCJOHLD_00299	4.3e-205	ydaJ	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
ENCJOHLD_00300	0.0	nox	-	-	C	-	-	-	NADH oxidase
ENCJOHLD_00301	6.37e-160	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
ENCJOHLD_00302	1.13e-218	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
ENCJOHLD_00303	2.82e-235	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
ENCJOHLD_00304	1.04e-211	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ENCJOHLD_00305	2.55e-225	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
ENCJOHLD_00306	2.87e-71	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
ENCJOHLD_00307	2.78e-65	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	positive regulation of macromolecule biosynthetic process
ENCJOHLD_00308	1.55e-150	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
ENCJOHLD_00309	2.31e-179	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
ENCJOHLD_00310	9.78e-190	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
ENCJOHLD_00311	5.04e-200	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
ENCJOHLD_00312	4.48e-206	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
ENCJOHLD_00313	1.19e-201	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
ENCJOHLD_00314	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
ENCJOHLD_00315	1.49e-170	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
ENCJOHLD_00316	1.28e-276	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
ENCJOHLD_00317	1.69e-257	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ENCJOHLD_00318	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
ENCJOHLD_00319	1.27e-129	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ENCJOHLD_00320	3.43e-163	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
ENCJOHLD_00321	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
ENCJOHLD_00322	3.7e-149	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
ENCJOHLD_00323	7.67e-198	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
ENCJOHLD_00324	7.29e-247	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
ENCJOHLD_00325	0.0	ydaO	-	-	E	-	-	-	amino acid
ENCJOHLD_00326	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
ENCJOHLD_00327	4e-54	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ENCJOHLD_00328	2.38e-140	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
ENCJOHLD_00329	3.67e-154	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
ENCJOHLD_00330	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
ENCJOHLD_00331	3.62e-249	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ENCJOHLD_00332	5.74e-108	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
ENCJOHLD_00333	4.66e-131	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
ENCJOHLD_00334	6.84e-167	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
ENCJOHLD_00335	2.33e-240	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
ENCJOHLD_00336	9.33e-177	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ENCJOHLD_00337	6.51e-178	phnE2	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter permease
ENCJOHLD_00338	3.33e-184	phnE1	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
ENCJOHLD_00339	2.8e-187	phnX	3.11.1.1	-	E	ko:K05306	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the HAD-like hydrolase superfamily. PhnX family
ENCJOHLD_00340	7.6e-270	phnW	2.6.1.37	-	E	ko:K03430	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000,ko01007	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
ENCJOHLD_00341	2.86e-245	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
ENCJOHLD_00342	3.17e-191	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
ENCJOHLD_00343	1.53e-212	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ENCJOHLD_00344	8.46e-77	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
ENCJOHLD_00345	2.33e-239	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
ENCJOHLD_00346	1.39e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
ENCJOHLD_00347	2.22e-153	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ENCJOHLD_00348	1.01e-51	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
ENCJOHLD_00349	6.22e-140	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ENCJOHLD_00350	2.05e-62	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ENCJOHLD_00351	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ENCJOHLD_00352	1.26e-117	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
ENCJOHLD_00353	1.11e-139	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
ENCJOHLD_00354	8.42e-50	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
ENCJOHLD_00355	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ENCJOHLD_00356	2.47e-253	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ENCJOHLD_00357	5.82e-141	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
ENCJOHLD_00358	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ENCJOHLD_00359	1.5e-82	-	-	-	L	-	-	-	nuclease
ENCJOHLD_00360	5.22e-229	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
ENCJOHLD_00366	1.26e-50	-	-	-	S	-	-	-	Bacteriophage holin
ENCJOHLD_00367	4.55e-64	-	-	-	-	-	-	-	-
ENCJOHLD_00368	6.9e-227	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
ENCJOHLD_00371	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
ENCJOHLD_00374	1.32e-126	-	-	-	S	-	-	-	Prophage endopeptidase tail
ENCJOHLD_00376	6.13e-166	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
ENCJOHLD_00383	1.21e-18	-	-	-	-	-	-	-	-
ENCJOHLD_00384	4.22e-06	-	-	-	-	-	-	-	-
ENCJOHLD_00385	7.01e-135	-	-	-	-	-	-	-	-
ENCJOHLD_00387	9.83e-54	-	-	-	S	-	-	-	Phage minor capsid protein 2
ENCJOHLD_00388	5.87e-139	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
ENCJOHLD_00389	2.83e-234	-	-	-	S	-	-	-	Phage terminase, large subunit, PBSX family
ENCJOHLD_00390	3.18e-61	-	-	-	L	-	-	-	transposase activity
ENCJOHLD_00391	9.79e-38	-	-	-	-	-	-	-	-
ENCJOHLD_00392	2.36e-25	-	-	-	-	-	-	-	-
ENCJOHLD_00396	3.86e-107	-	-	-	S	-	-	-	Phage transcriptional regulator, ArpU family
ENCJOHLD_00397	1.93e-27	-	-	-	-	-	-	-	-
ENCJOHLD_00398	9.86e-39	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
ENCJOHLD_00399	1.26e-19	-	-	-	S	-	-	-	YjzC-like protein
ENCJOHLD_00401	6.39e-89	-	-	-	L	-	-	-	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
ENCJOHLD_00402	3.19e-122	-	-	-	-	-	-	-	-
ENCJOHLD_00403	1.97e-110	-	-	-	S	-	-	-	Pfam:DUF3816
ENCJOHLD_00404	1.21e-306	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ENCJOHLD_00405	1.54e-144	-	-	-	-	-	-	-	-
ENCJOHLD_00406	2.94e-227	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
ENCJOHLD_00407	3.84e-185	-	-	-	S	-	-	-	Peptidase_C39 like family
ENCJOHLD_00408	1.04e-120	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
ENCJOHLD_00409	3.38e-150	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
ENCJOHLD_00410	9.38e-189	-	-	-	KT	-	-	-	helix_turn_helix, mercury resistance
ENCJOHLD_00411	3.41e-295	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
ENCJOHLD_00412	1.86e-123	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
ENCJOHLD_00413	1.2e-240	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
ENCJOHLD_00414	7.14e-157	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
ENCJOHLD_00415	2.76e-117	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
ENCJOHLD_00416	2e-238	iunH3	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
ENCJOHLD_00417	3.55e-127	ywjB	-	-	H	-	-	-	RibD C-terminal domain
ENCJOHLD_00418	1.97e-258	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
ENCJOHLD_00419	9.01e-155	-	-	-	S	-	-	-	Membrane
ENCJOHLD_00420	2.11e-199	mleP3	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
ENCJOHLD_00421	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
ENCJOHLD_00422	3.46e-251	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
ENCJOHLD_00423	1.25e-163	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
ENCJOHLD_00424	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
ENCJOHLD_00425	5.97e-106	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
ENCJOHLD_00426	7.69e-134	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
ENCJOHLD_00427	2.17e-222	-	-	-	S	-	-	-	Conserved hypothetical protein 698
ENCJOHLD_00428	2.06e-194	rlrG	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
ENCJOHLD_00429	0.0	tagE5	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
ENCJOHLD_00430	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
ENCJOHLD_00432	9.92e-88	-	-	-	M	-	-	-	LysM domain
ENCJOHLD_00433	1.6e-119	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
ENCJOHLD_00434	4.23e-215	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
ENCJOHLD_00435	2.26e-268	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
ENCJOHLD_00436	6.27e-166	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
ENCJOHLD_00437	1.16e-72	cmd	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
ENCJOHLD_00438	4.77e-100	yphH	-	-	S	-	-	-	Cupin domain
ENCJOHLD_00439	7.37e-103	-	-	-	K	-	-	-	transcriptional regulator, MerR family
ENCJOHLD_00440	1.3e-63	-	-	-	H	-	-	-	RibD C-terminal domain
ENCJOHLD_00442	1.46e-299	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
ENCJOHLD_00443	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
ENCJOHLD_00444	6.53e-134	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
ENCJOHLD_00445	1.74e-156	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
ENCJOHLD_00447	2.93e-151	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ENCJOHLD_00448	4.33e-139	thgA3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
ENCJOHLD_00449	1.03e-150	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
ENCJOHLD_00450	1.58e-146	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
ENCJOHLD_00451	9.82e-111	-	-	-	-	-	-	-	-
ENCJOHLD_00452	4.4e-112	yvbK	-	-	K	-	-	-	GNAT family
ENCJOHLD_00453	2.8e-49	-	-	-	-	-	-	-	-
ENCJOHLD_00454	2.81e-64	-	-	-	-	-	-	-	-
ENCJOHLD_00455	5.46e-145	pgm8	-	-	G	-	-	-	Histidine phosphatase superfamily (branch 1)
ENCJOHLD_00456	2.65e-78	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
ENCJOHLD_00457	1.57e-202	-	-	-	K	-	-	-	LysR substrate binding domain
ENCJOHLD_00458	2.53e-134	-	-	-	GM	-	-	-	NAD(P)H-binding
ENCJOHLD_00459	2.88e-248	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
ENCJOHLD_00460	5.85e-194	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
ENCJOHLD_00461	1.2e-181	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
ENCJOHLD_00462	4.83e-105	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
ENCJOHLD_00463	2.14e-98	-	-	-	C	-	-	-	Flavodoxin
ENCJOHLD_00464	2.78e-160	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	reductase
ENCJOHLD_00465	1.43e-114	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
ENCJOHLD_00466	7.8e-113	-	-	-	GM	-	-	-	NAD(P)H-binding
ENCJOHLD_00467	2.11e-132	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
ENCJOHLD_00468	5.63e-98	-	-	-	K	-	-	-	Transcriptional regulator
ENCJOHLD_00470	5.87e-31	-	-	-	C	-	-	-	Flavodoxin
ENCJOHLD_00471	1.69e-08	adhR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
ENCJOHLD_00472	9.99e-147	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
ENCJOHLD_00473	2.41e-165	-	-	-	C	-	-	-	Aldo keto reductase
ENCJOHLD_00474	4.02e-181	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
ENCJOHLD_00475	3.08e-178	-	-	-	EGP	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
ENCJOHLD_00476	5.55e-106	-	-	-	GM	-	-	-	NAD(P)H-binding
ENCJOHLD_00477	2.1e-99	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
ENCJOHLD_00478	1.04e-124	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
ENCJOHLD_00479	1.19e-160	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
ENCJOHLD_00480	1.12e-105	-	-	-	-	-	-	-	-
ENCJOHLD_00481	3.73e-131	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
ENCJOHLD_00482	3.45e-285	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
ENCJOHLD_00483	1.52e-131	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
ENCJOHLD_00484	4.96e-247	-	-	-	C	-	-	-	Aldo/keto reductase family
ENCJOHLD_00486	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
ENCJOHLD_00487	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
ENCJOHLD_00488	3.17e-314	-	-	-	EGP	-	-	-	Major Facilitator
ENCJOHLD_00491	6.17e-317	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
ENCJOHLD_00492	1.59e-143	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
ENCJOHLD_00493	6.88e-71	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
ENCJOHLD_00494	1.66e-199	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
ENCJOHLD_00495	1.06e-138	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
ENCJOHLD_00496	3.05e-126	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
ENCJOHLD_00497	9.53e-284	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
ENCJOHLD_00498	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
ENCJOHLD_00499	4.68e-190	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
ENCJOHLD_00500	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
ENCJOHLD_00501	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC
ENCJOHLD_00502	2.33e-265	-	-	-	EGP	-	-	-	Major facilitator Superfamily
ENCJOHLD_00503	2.67e-220	ropB	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
ENCJOHLD_00504	1.76e-298	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
ENCJOHLD_00505	0.0	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
ENCJOHLD_00506	1.36e-204	-	-	-	I	-	-	-	alpha/beta hydrolase fold
ENCJOHLD_00507	1.75e-168	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
ENCJOHLD_00508	0.0	-	-	-	-	-	-	-	-
ENCJOHLD_00509	2e-52	-	-	-	S	-	-	-	Cytochrome B5
ENCJOHLD_00510	5.02e-117	pts21A	-	-	G	ko:K02755	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
ENCJOHLD_00511	1.38e-277	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
ENCJOHLD_00512	2.82e-163	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
ENCJOHLD_00513	3.83e-135	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ENCJOHLD_00514	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
ENCJOHLD_00515	1.56e-108	-	-	-	-	-	-	-	-
ENCJOHLD_00516	5.97e-96	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
ENCJOHLD_00517	5.32e-242	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
ENCJOHLD_00518	2.09e-244	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ENCJOHLD_00519	3.7e-30	-	-	-	-	-	-	-	-
ENCJOHLD_00520	5.24e-134	-	-	-	-	-	-	-	-
ENCJOHLD_00521	5.12e-212	-	-	-	K	-	-	-	LysR substrate binding domain
ENCJOHLD_00522	1.24e-313	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
ENCJOHLD_00523	0.0	-	4.1.1.98	-	H	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
ENCJOHLD_00524	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
ENCJOHLD_00525	2.27e-181	-	-	-	S	-	-	-	zinc-ribbon domain
ENCJOHLD_00527	4.29e-50	-	-	-	-	-	-	-	-
ENCJOHLD_00528	1.48e-171	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
ENCJOHLD_00529	4.07e-232	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
ENCJOHLD_00530	0.0	-	-	-	I	-	-	-	acetylesterase activity
ENCJOHLD_00531	1.62e-296	-	-	-	M	-	-	-	Collagen binding domain
ENCJOHLD_00532	6.92e-206	yicL	-	-	EG	-	-	-	EamA-like transporter family
ENCJOHLD_00533	3.03e-166	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
ENCJOHLD_00534	1.44e-226	-	4.1.1.52	-	S	ko:K22213	-	ko00000,ko01000	Amidohydrolase
ENCJOHLD_00535	1.98e-142	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
ENCJOHLD_00536	8.76e-63	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
ENCJOHLD_00537	8.78e-206	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
ENCJOHLD_00538	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
ENCJOHLD_00539	6.37e-125	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
ENCJOHLD_00540	3.29e-153	ydgI3	-	-	C	-	-	-	Nitroreductase family
ENCJOHLD_00541	0.0	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
ENCJOHLD_00542	7.52e-139	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
ENCJOHLD_00543	2.76e-196	WQ51_06230	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
ENCJOHLD_00544	7.28e-218	XK27_00670	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
ENCJOHLD_00545	0.0	-	-	-	-	-	-	-	-
ENCJOHLD_00546	3.08e-80	-	-	-	-	-	-	-	-
ENCJOHLD_00547	7.52e-240	-	-	-	S	-	-	-	Cell surface protein
ENCJOHLD_00548	1.27e-137	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
ENCJOHLD_00549	1.91e-124	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
ENCJOHLD_00550	1.61e-157	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
ENCJOHLD_00551	1.28e-180	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
ENCJOHLD_00552	3.79e-192	livM	-	-	E	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
ENCJOHLD_00553	9.73e-197	livH	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
ENCJOHLD_00554	3.38e-261	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
ENCJOHLD_00556	4.69e-43	-	-	-	-	-	-	-	-
ENCJOHLD_00557	6.9e-168	zmp3	-	-	O	-	-	-	Zinc-dependent metalloprotease
ENCJOHLD_00558	2.88e-106	gtcA3	-	-	S	-	-	-	GtrA-like protein
ENCJOHLD_00559	4.08e-158	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
ENCJOHLD_00560	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
ENCJOHLD_00561	1.18e-94	usp2	-	-	T	-	-	-	Belongs to the universal stress protein A family
ENCJOHLD_00562	2.87e-61	-	-	-	-	-	-	-	-
ENCJOHLD_00563	1.81e-150	-	-	-	S	-	-	-	SNARE associated Golgi protein
ENCJOHLD_00564	8.58e-65	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
ENCJOHLD_00565	7.89e-124	-	-	-	P	-	-	-	Cadmium resistance transporter
ENCJOHLD_00566	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
ENCJOHLD_00567	9.99e-238	-	-	-	P	-	-	-	Concanavalin A-like lectin/glucanases superfamily
ENCJOHLD_00568	0.0	-	-	-	P	-	-	-	Concanavalin A-like lectin/glucanases superfamily
ENCJOHLD_00569	2.03e-84	-	-	-	-	-	-	-	-
ENCJOHLD_00570	1.93e-205	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
ENCJOHLD_00571	2.86e-72	-	-	-	-	-	-	-	-
ENCJOHLD_00572	1.02e-193	-	-	-	K	-	-	-	Helix-turn-helix domain
ENCJOHLD_00573	3.91e-100	pts23A	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
ENCJOHLD_00574	7.47e-70	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
ENCJOHLD_00575	0.0	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
ENCJOHLD_00576	0.0	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
ENCJOHLD_00577	7.48e-236	-	-	-	GM	-	-	-	Male sterility protein
ENCJOHLD_00578	4.4e-101	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
ENCJOHLD_00579	4.61e-101	-	-	-	M	-	-	-	LysM domain
ENCJOHLD_00580	3.03e-130	-	-	-	M	-	-	-	Lysin motif
ENCJOHLD_00581	1.4e-138	-	-	-	S	-	-	-	SdpI/YhfL protein family
ENCJOHLD_00582	2.63e-71	nudA	-	-	S	-	-	-	ASCH
ENCJOHLD_00583	5.76e-212	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
ENCJOHLD_00584	3.57e-120	-	-	-	-	-	-	-	-
ENCJOHLD_00585	1.92e-155	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
ENCJOHLD_00586	3.55e-281	-	-	-	T	-	-	-	diguanylate cyclase
ENCJOHLD_00587	7.43e-97	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
ENCJOHLD_00588	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
ENCJOHLD_00589	1.17e-214	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
ENCJOHLD_00590	2.14e-95	-	-	-	-	-	-	-	-
ENCJOHLD_00591	6.54e-168	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
ENCJOHLD_00592	5.37e-222	-	-	-	C	-	-	-	C4-dicarboxylate transmembrane transporter activity
ENCJOHLD_00593	2.51e-150	-	-	-	GM	-	-	-	NAD(P)H-binding
ENCJOHLD_00594	1.6e-118	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
ENCJOHLD_00595	5.51e-101	yphH	-	-	S	-	-	-	Cupin domain
ENCJOHLD_00596	2.06e-78	-	-	-	I	-	-	-	sulfurtransferase activity
ENCJOHLD_00597	5.44e-178	gdh	1.1.1.47, 1.1.1.53	-	IQ	ko:K00034,ko:K00038	ko00030,ko00140,ko01100,ko01120,ko01200,map00030,map00140,map01100,map01120,map01200	ko00000,ko00001,ko01000	reductase
ENCJOHLD_00598	8.38e-152	-	-	-	GM	-	-	-	NAD(P)H-binding
ENCJOHLD_00599	2.31e-277	-	-	-	-	-	-	-	-
ENCJOHLD_00600	0.0	-	-	-	V	ko:K06147,ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
ENCJOHLD_00601	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
ENCJOHLD_00602	1.51e-225	-	-	-	O	-	-	-	protein import
ENCJOHLD_00603	1.67e-292	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
ENCJOHLD_00604	2.43e-208	yhxD	-	-	IQ	-	-	-	KR domain
ENCJOHLD_00606	9.38e-91	-	-	-	-	-	-	-	-
ENCJOHLD_00607	1.74e-185	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
ENCJOHLD_00608	0.0	-	-	-	E	-	-	-	Amino Acid
ENCJOHLD_00609	1.67e-86	lysM	-	-	M	-	-	-	LysM domain
ENCJOHLD_00610	4.2e-286	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
ENCJOHLD_00611	6.8e-272	adhC	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
ENCJOHLD_00612	0.0	copA	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
ENCJOHLD_00613	3.65e-59	-	-	-	S	-	-	-	Cupredoxin-like domain
ENCJOHLD_00614	1.36e-84	-	-	-	S	-	-	-	Cupredoxin-like domain
ENCJOHLD_00615	0.0	aapA	-	-	M	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
ENCJOHLD_00616	2.81e-181	-	-	-	K	-	-	-	Helix-turn-helix domain
ENCJOHLD_00617	1.47e-51	-	-	-	S	ko:K07343	-	ko00000	TfoX C-terminal domain
ENCJOHLD_00618	3.05e-289	hpk9	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
ENCJOHLD_00619	0.0	-	-	-	-	-	-	-	-
ENCJOHLD_00620	1.56e-98	-	-	-	-	-	-	-	-
ENCJOHLD_00621	1.11e-240	-	-	-	S	-	-	-	Cell surface protein
ENCJOHLD_00622	6.02e-137	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
ENCJOHLD_00623	9.33e-226	-	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
ENCJOHLD_00624	1.22e-88	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
ENCJOHLD_00625	3.33e-149	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
ENCJOHLD_00626	1.59e-243	ynjC	-	-	S	-	-	-	Cell surface protein
ENCJOHLD_00627	2.7e-131	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
ENCJOHLD_00628	1.47e-83	-	-	-	-	-	-	-	-
ENCJOHLD_00629	8.34e-311	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
ENCJOHLD_00630	4.13e-157	-	-	-	-	-	-	-	-
ENCJOHLD_00631	4.31e-149	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
ENCJOHLD_00632	3.25e-81	ytcD	-	-	K	-	-	-	Transcriptional regulator, HxlR family
ENCJOHLD_00633	1.81e-272	-	-	-	EGP	-	-	-	Major Facilitator
ENCJOHLD_00634	7.81e-148	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
ENCJOHLD_00635	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
ENCJOHLD_00636	8.01e-174	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
ENCJOHLD_00637	1.77e-282	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
ENCJOHLD_00638	1.59e-130	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
ENCJOHLD_00639	2.18e-215	-	-	-	GM	-	-	-	NmrA-like family
ENCJOHLD_00640	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
ENCJOHLD_00641	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
ENCJOHLD_00642	1.62e-62	-	-	-	S	-	-	-	Domain of unknown function (DUF1905)
ENCJOHLD_00643	2.56e-83	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
ENCJOHLD_00644	2.69e-169	-	-	-	S	-	-	-	KR domain
ENCJOHLD_00645	5.79e-126	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
ENCJOHLD_00646	5.76e-243	-	1.1.1.219	-	GM	ko:K00091	-	ko00000,ko01000	Male sterility protein
ENCJOHLD_00647	7.34e-129	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
ENCJOHLD_00648	6.6e-228	ydhF	-	-	S	-	-	-	Aldo keto reductase
ENCJOHLD_00649	0.0	yfjF	-	-	U	-	-	-	Sugar (and other) transporter
ENCJOHLD_00650	1.08e-140	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
ENCJOHLD_00651	7.05e-219	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
ENCJOHLD_00652	6.37e-188	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
ENCJOHLD_00653	1.81e-228	fhuB	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ENCJOHLD_00654	1.35e-218	fhuG	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ENCJOHLD_00655	3.74e-120	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
ENCJOHLD_00656	3.2e-209	-	-	-	GM	-	-	-	NmrA-like family
ENCJOHLD_00657	2.47e-168	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
ENCJOHLD_00658	9.43e-95	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
ENCJOHLD_00659	1.83e-194	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
ENCJOHLD_00660	3.86e-85	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
ENCJOHLD_00661	9.53e-273	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
ENCJOHLD_00662	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
ENCJOHLD_00663	1.32e-138	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
ENCJOHLD_00664	4.33e-72	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
ENCJOHLD_00665	1.87e-107	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
ENCJOHLD_00666	1.86e-265	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
ENCJOHLD_00667	1.97e-151	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
ENCJOHLD_00668	0.0	lepA2	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
ENCJOHLD_00669	0.0	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
ENCJOHLD_00670	4.54e-202	-	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NADH pyrophosphatase zinc ribbon domain
ENCJOHLD_00671	2.72e-208	-	-	-	K	-	-	-	LysR substrate binding domain
ENCJOHLD_00672	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
ENCJOHLD_00673	0.0	-	-	-	S	-	-	-	MucBP domain
ENCJOHLD_00674	2.72e-126	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
ENCJOHLD_00675	1.46e-60	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
ENCJOHLD_00676	1.05e-179	-	-	-	K	-	-	-	DeoR C terminal sensor domain
ENCJOHLD_00677	1.97e-228	rhaR	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
ENCJOHLD_00678	4.67e-314	iolF	-	-	P	ko:K06610	-	ko00000,ko02000	Sugar (and other) transporter
ENCJOHLD_00679	0.0	rhaB	2.7.1.5	-	F	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
ENCJOHLD_00680	4.22e-74	rhaM	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Involved in the anomeric conversion of L-rhamnose
ENCJOHLD_00681	0.0	rhaA	2.7.1.5, 5.3.1.14	-	G	ko:K00848,ko:K01813	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	L-rhamnose isomerase (RhaA)
ENCJOHLD_00682	1.31e-210	rhaD	4.1.2.19	-	H	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
ENCJOHLD_00683	1.45e-162	-	-	-	S	-	-	-	Membrane
ENCJOHLD_00684	4.04e-94	yueI	-	-	S	-	-	-	Protein of unknown function (DUF1694)
ENCJOHLD_00685	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
ENCJOHLD_00686	5.03e-95	-	-	-	K	-	-	-	Transcriptional regulator
ENCJOHLD_00687	0.0	pox4	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
ENCJOHLD_00688	1.97e-256	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
ENCJOHLD_00690	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
ENCJOHLD_00691	1.51e-85	-	-	-	KOT	ko:K07813	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01002	May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
ENCJOHLD_00692	9.62e-19	-	-	-	-	-	-	-	-
ENCJOHLD_00693	3.78e-212	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
ENCJOHLD_00694	4.29e-173	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
ENCJOHLD_00695	1.32e-101	nrp	-	-	K	ko:K16509	-	ko00000	ArsC family
ENCJOHLD_00696	0.0	katA	1.11.1.6	-	C	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	Belongs to the catalase family
ENCJOHLD_00697	1.96e-21	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
ENCJOHLD_00698	1.06e-16	-	-	-	-	-	-	-	-
ENCJOHLD_00699	1.22e-115	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
ENCJOHLD_00700	2.43e-91	-	-	-	S	-	-	-	Pyrimidine dimer DNA glycosylase
ENCJOHLD_00701	7.62e-290	-	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
ENCJOHLD_00702	5.02e-158	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
ENCJOHLD_00703	3.44e-262	araR	-	-	K	ko:K02103	-	ko00000,ko03000	Transcriptional regulator
ENCJOHLD_00704	0.0	araP	-	-	U	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
ENCJOHLD_00705	0.0	araB	2.7.1.16	-	G	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	carbohydrate kinase FGGY
ENCJOHLD_00706	1.06e-175	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
ENCJOHLD_00707	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
ENCJOHLD_00708	6.83e-133	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
ENCJOHLD_00709	1.73e-93	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
ENCJOHLD_00710	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
ENCJOHLD_00711	3.05e-161	-	-	-	K	ko:K02444	-	ko00000,ko03000	DeoR C terminal sensor domain
ENCJOHLD_00712	3.99e-106	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
ENCJOHLD_00713	6e-60	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
ENCJOHLD_00714	8.37e-296	gatC	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
ENCJOHLD_00715	5.26e-247	-	1.1.1.14	-	C	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
ENCJOHLD_00716	4.53e-146	gph3	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
ENCJOHLD_00717	0.0	-	-	-	G	ko:K03483	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
ENCJOHLD_00718	6.42e-101	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
ENCJOHLD_00719	8.52e-60	ulaB	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system galactitol-specific IIB component
ENCJOHLD_00720	1.17e-305	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
ENCJOHLD_00721	8.34e-147	tal	2.2.1.2	-	F	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ENCJOHLD_00722	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ENCJOHLD_00723	2.58e-186	yxeH	-	-	S	-	-	-	hydrolase
ENCJOHLD_00724	1.04e-223	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
ENCJOHLD_00726	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
ENCJOHLD_00727	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
ENCJOHLD_00728	1.08e-221	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
ENCJOHLD_00729	0.0	treP	2.4.1.64	GH65	G	ko:K05342	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
ENCJOHLD_00730	1.3e-203	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
ENCJOHLD_00731	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
ENCJOHLD_00732	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
ENCJOHLD_00733	0.0	pbg9	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
ENCJOHLD_00734	3.25e-252	-	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
ENCJOHLD_00735	8.71e-202	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ENCJOHLD_00736	0.0	pts32BC	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
ENCJOHLD_00737	1.73e-178	yleF	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
ENCJOHLD_00738	1.48e-103	-	2.7.1.208	-	G	ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
ENCJOHLD_00739	4.75e-96	-	-	-	G	ko:K11201	-	ko00000,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
ENCJOHLD_00740	0.0	pts31BC	-	-	G	ko:K11202,ko:K11203	-	ko00000,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
ENCJOHLD_00741	4.72e-286	malY	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
ENCJOHLD_00742	0.0	-	-	-	G	-	-	-	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
ENCJOHLD_00743	3.72e-200	bglG4	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
ENCJOHLD_00744	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
ENCJOHLD_00745	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
ENCJOHLD_00746	2.26e-269	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
ENCJOHLD_00747	1.76e-204	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
ENCJOHLD_00748	1.25e-211	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ENCJOHLD_00749	0.0	pts29C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
ENCJOHLD_00750	5.44e-174	-	-	-	K	-	-	-	UTRA domain
ENCJOHLD_00751	2.63e-200	estA	-	-	S	-	-	-	Putative esterase
ENCJOHLD_00752	2.09e-83	-	-	-	-	-	-	-	-
ENCJOHLD_00753	1.12e-262	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
ENCJOHLD_00754	1.73e-215	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
ENCJOHLD_00755	9.22e-211	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
ENCJOHLD_00756	1.64e-202	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
ENCJOHLD_00757	8.13e-206	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ENCJOHLD_00758	1.71e-207	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ENCJOHLD_00759	1.4e-282	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
ENCJOHLD_00760	4.62e-224	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
ENCJOHLD_00761	7.89e-213	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ENCJOHLD_00762	3.65e-172	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
ENCJOHLD_00763	1.23e-228	apbE3	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
ENCJOHLD_00764	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
ENCJOHLD_00765	4.07e-85	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
ENCJOHLD_00766	8.93e-249	tas3	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
ENCJOHLD_00767	3.69e-232	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
ENCJOHLD_00768	4.27e-253	galM3	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
ENCJOHLD_00769	0.0	lacP	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
ENCJOHLD_00770	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
ENCJOHLD_00771	2.72e-237	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
ENCJOHLD_00772	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
ENCJOHLD_00773	1.65e-286	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ENCJOHLD_00774	5.14e-245	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
ENCJOHLD_00775	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
ENCJOHLD_00776	1.19e-234	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
ENCJOHLD_00777	3.4e-100	-	-	-	K	ko:K07726	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
ENCJOHLD_00778	1.59e-129	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
ENCJOHLD_00779	7.48e-235	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
ENCJOHLD_00780	5.06e-298	-	-	-	P	ko:K06610	-	ko00000,ko02000	Major Facilitator Superfamily
ENCJOHLD_00781	0.0	ram2	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
ENCJOHLD_00782	3.03e-295	-	-	-	P	ko:K06610	-	ko00000,ko02000	Sugar (and other) transporter
ENCJOHLD_00783	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
ENCJOHLD_00784	4.73e-242	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
ENCJOHLD_00785	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
ENCJOHLD_00786	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
ENCJOHLD_00787	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
ENCJOHLD_00788	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
ENCJOHLD_00789	1.95e-140	aqpZ	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
ENCJOHLD_00790	4.03e-283	-	-	-	S	-	-	-	associated with various cellular activities
ENCJOHLD_00791	9.34e-317	-	-	-	S	-	-	-	Putative metallopeptidase domain
ENCJOHLD_00792	1.03e-65	-	-	-	-	-	-	-	-
ENCJOHLD_00793	1.72e-135	yezE	-	-	K	ko:K16137	-	ko00000,ko03000	Bacterial regulatory proteins, tetR family
ENCJOHLD_00794	7.83e-60	-	-	-	-	-	-	-	-
ENCJOHLD_00795	4.23e-129	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
ENCJOHLD_00796	2.48e-159	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
ENCJOHLD_00797	1.83e-235	-	-	-	S	-	-	-	Cell surface protein
ENCJOHLD_00798	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
ENCJOHLD_00799	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
ENCJOHLD_00800	5.23e-107	yoaA	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ENCJOHLD_00801	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
ENCJOHLD_00802	1.82e-152	rcfA	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
ENCJOHLD_00803	2.98e-44	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
ENCJOHLD_00804	7.94e-124	dpsB	-	-	P	-	-	-	Belongs to the Dps family
ENCJOHLD_00805	1.01e-26	-	-	-	-	-	-	-	-
ENCJOHLD_00806	4.82e-55	yrkD	-	-	S	-	-	-	Metal-sensitive transcriptional repressor
ENCJOHLD_00807	5.73e-73	trxA3	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin-like domain
ENCJOHLD_00808	8.08e-184	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
ENCJOHLD_00809	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
ENCJOHLD_00810	3.28e-231	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
ENCJOHLD_00811	1.44e-163	-	-	-	S	-	-	-	Gram-negative-bacterium-type cell wall biogenesis
ENCJOHLD_00812	8.41e-175	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
ENCJOHLD_00813	1.69e-230	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
ENCJOHLD_00814	1.72e-129	-	-	-	K	-	-	-	transcriptional regulator
ENCJOHLD_00815	4.61e-204	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
ENCJOHLD_00816	1.22e-68	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2316)
ENCJOHLD_00817	5.13e-138	-	-	-	-	-	-	-	-
ENCJOHLD_00819	5.77e-81	-	-	-	-	-	-	-	-
ENCJOHLD_00820	2.15e-71	-	-	-	-	-	-	-	-
ENCJOHLD_00821	1.44e-107	-	-	-	M	-	-	-	PFAM NLP P60 protein
ENCJOHLD_00822	0.0	gadB	4.1.1.15, 4.1.2.27	-	E	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Belongs to the group II decarboxylase family
ENCJOHLD_00823	4.45e-38	-	-	-	-	-	-	-	-
ENCJOHLD_00824	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
ENCJOHLD_00825	3.81e-150	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
ENCJOHLD_00826	5.33e-114	-	-	-	K	-	-	-	Winged helix DNA-binding domain
ENCJOHLD_00827	3.15e-174	yesN	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
ENCJOHLD_00828	5.48e-171	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
ENCJOHLD_00829	1.36e-245	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
ENCJOHLD_00830	0.0	-	-	-	-	-	-	-	-
ENCJOHLD_00831	3.42e-212	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
ENCJOHLD_00832	1.58e-66	-	-	-	-	-	-	-	-
ENCJOHLD_00833	6.47e-124	-	-	-	K	ko:K22041	-	ko00000,ko03000	transcriptional regulator
ENCJOHLD_00834	6.94e-117	ymdB	-	-	S	-	-	-	Macro domain protein
ENCJOHLD_00835	5.43e-190	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
ENCJOHLD_00836	3.68e-57	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
ENCJOHLD_00837	2.07e-102	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
ENCJOHLD_00838	2.57e-171	-	-	-	S	-	-	-	Putative threonine/serine exporter
ENCJOHLD_00839	1.36e-209	yvgN	-	-	C	-	-	-	Aldo keto reductase
ENCJOHLD_00840	2.8e-205	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
ENCJOHLD_00841	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
ENCJOHLD_00842	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
ENCJOHLD_00843	1.14e-110	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
ENCJOHLD_00844	6.1e-101	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
ENCJOHLD_00845	5.99e-231	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
ENCJOHLD_00846	2.52e-282	mdtG	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
ENCJOHLD_00847	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
ENCJOHLD_00848	8.75e-85	-	-	-	S	-	-	-	Protein of unknown function (DUF1398)
ENCJOHLD_00849	2.55e-65	-	-	-	-	-	-	-	-
ENCJOHLD_00850	7.21e-35	-	-	-	-	-	-	-	-
ENCJOHLD_00851	1.77e-314	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
ENCJOHLD_00852	2.83e-95	-	-	-	S	-	-	-	COG NOG18757 non supervised orthologous group
ENCJOHLD_00853	4.26e-54	-	-	-	-	-	-	-	-
ENCJOHLD_00854	4.83e-98	copR	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
ENCJOHLD_00855	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
ENCJOHLD_00856	4.38e-243	pva2	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
ENCJOHLD_00857	2.55e-145	-	-	-	S	-	-	-	VIT family
ENCJOHLD_00858	2.66e-155	-	-	-	S	-	-	-	membrane
ENCJOHLD_00859	1.63e-203	-	-	-	EG	-	-	-	EamA-like transporter family
ENCJOHLD_00860	2.52e-107	-	-	-	S	ko:K02348	-	ko00000	GNAT family
ENCJOHLD_00861	3.57e-150	-	-	-	GM	-	-	-	NmrA-like family
ENCJOHLD_00862	4.79e-21	-	-	-	-	-	-	-	-
ENCJOHLD_00863	9.27e-74	-	-	-	-	-	-	-	-
ENCJOHLD_00864	4.58e-103	hsp3	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
ENCJOHLD_00865	1.11e-111	-	-	-	-	-	-	-	-
ENCJOHLD_00866	2.11e-82	-	-	-	-	-	-	-	-
ENCJOHLD_00867	7.08e-275	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
ENCJOHLD_00868	1.7e-70	-	-	-	-	-	-	-	-
ENCJOHLD_00869	1.41e-86	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
ENCJOHLD_00870	9.97e-94	spxA	-	-	P	ko:K16509	-	ko00000	ArsC family
ENCJOHLD_00871	2.14e-86	-	-	-	K	ko:K22296	-	ko00000,ko03000	Winged helix DNA-binding domain
ENCJOHLD_00872	1.12e-208	-	-	-	GM	-	-	-	NmrA-like family
ENCJOHLD_00873	1.65e-112	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
ENCJOHLD_00874	2.48e-215	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
ENCJOHLD_00875	9.04e-317	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
ENCJOHLD_00876	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
ENCJOHLD_00877	3.58e-36	-	-	-	S	-	-	-	Belongs to the LOG family
ENCJOHLD_00878	5.32e-12	-	-	-	S	-	-	-	Short C-terminal domain
ENCJOHLD_00881	2.3e-226	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyltransferase like family 2
ENCJOHLD_00882	3.26e-88	-	-	-	-	-	-	-	-
ENCJOHLD_00883	1.01e-100	-	-	-	-	-	-	-	-
ENCJOHLD_00884	6.62e-278	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
ENCJOHLD_00885	1.83e-121	-	-	-	-	-	-	-	-
ENCJOHLD_00886	7.22e-149	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ENCJOHLD_00887	7.68e-48	ynzC	-	-	S	-	-	-	UPF0291 protein
ENCJOHLD_00888	3.96e-44	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
ENCJOHLD_00889	1.71e-152	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
ENCJOHLD_00890	3.65e-172	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
ENCJOHLD_00891	1.02e-66	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
ENCJOHLD_00892	1.92e-239	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ENCJOHLD_00893	2.92e-172	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
ENCJOHLD_00894	6.33e-185	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
ENCJOHLD_00895	1.55e-193	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ENCJOHLD_00896	3.01e-165	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
ENCJOHLD_00897	1.98e-112	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
ENCJOHLD_00898	3.17e-190	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ENCJOHLD_00899	1.13e-175	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
ENCJOHLD_00900	4.64e-294	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
ENCJOHLD_00901	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
ENCJOHLD_00902	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ENCJOHLD_00903	9.74e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
ENCJOHLD_00904	4.46e-275	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
ENCJOHLD_00905	2.95e-65	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
ENCJOHLD_00906	3.28e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
ENCJOHLD_00907	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ENCJOHLD_00908	3.04e-71	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ENCJOHLD_00909	0.0	-	-	-	G	-	-	-	Major Facilitator
ENCJOHLD_00910	6.08e-274	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ENCJOHLD_00911	2.71e-120	-	-	-	-	-	-	-	-
ENCJOHLD_00912	6.72e-302	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
ENCJOHLD_00913	5.99e-246	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
ENCJOHLD_00914	1.45e-114	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ENCJOHLD_00915	6.29e-221	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ENCJOHLD_00916	7.56e-242	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
ENCJOHLD_00917	1.19e-169	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
ENCJOHLD_00918	4.42e-248	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
ENCJOHLD_00919	4.52e-111	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ENCJOHLD_00920	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
ENCJOHLD_00921	2.54e-266	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
ENCJOHLD_00922	8.49e-266	pbpX2	-	-	V	-	-	-	Beta-lactamase
ENCJOHLD_00923	8.59e-27	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
ENCJOHLD_00924	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ENCJOHLD_00925	1.14e-297	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
ENCJOHLD_00926	5.75e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ENCJOHLD_00927	1.68e-312	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
ENCJOHLD_00928	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
ENCJOHLD_00929	1.73e-67	-	-	-	-	-	-	-	-
ENCJOHLD_00930	4.78e-65	-	-	-	-	-	-	-	-
ENCJOHLD_00931	1.11e-147	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
ENCJOHLD_00932	2.04e-226	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
ENCJOHLD_00933	3.13e-172	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
ENCJOHLD_00934	2.56e-76	-	-	-	-	-	-	-	-
ENCJOHLD_00935	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ENCJOHLD_00936	8.2e-102	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
ENCJOHLD_00937	1.35e-147	yjcF	-	-	J	-	-	-	HAD-hyrolase-like
ENCJOHLD_00938	2.65e-213	-	-	-	G	-	-	-	Fructosamine kinase
ENCJOHLD_00939	2.83e-200	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
ENCJOHLD_00940	2.47e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
ENCJOHLD_00941	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
ENCJOHLD_00942	2.15e-131	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ENCJOHLD_00943	4.35e-204	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ENCJOHLD_00944	1.84e-284	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
ENCJOHLD_00945	1.42e-217	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ENCJOHLD_00946	3.65e-166	-	-	-	C	-	-	-	Enoyl-(Acyl carrier protein) reductase
ENCJOHLD_00947	2.32e-194	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
ENCJOHLD_00948	1.09e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
ENCJOHLD_00949	9.21e-94	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
ENCJOHLD_00950	9.71e-229	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
ENCJOHLD_00951	7.7e-110	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ENCJOHLD_00952	1.15e-94	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
ENCJOHLD_00953	7.92e-217	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ENCJOHLD_00954	2.84e-189	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
ENCJOHLD_00955	8.64e-224	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
ENCJOHLD_00956	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
ENCJOHLD_00957	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
ENCJOHLD_00958	1.74e-251	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
ENCJOHLD_00959	1.18e-85	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
ENCJOHLD_00960	2.45e-213	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
ENCJOHLD_00961	2.59e-256	-	-	-	-	-	-	-	-
ENCJOHLD_00962	1.74e-252	-	-	-	-	-	-	-	-
ENCJOHLD_00963	2.11e-170	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
ENCJOHLD_00964	4.36e-208	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
ENCJOHLD_00965	0.000138	yjdF	-	-	S	-	-	-	Protein of unknown function (DUF2992)
ENCJOHLD_00966	1.28e-148	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
ENCJOHLD_00967	3.89e-94	-	-	-	K	-	-	-	MarR family
ENCJOHLD_00968	6.64e-109	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
ENCJOHLD_00970	3.43e-203	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
ENCJOHLD_00971	1.27e-174	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
ENCJOHLD_00972	2.08e-265	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
ENCJOHLD_00973	1.11e-134	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
ENCJOHLD_00974	0.0	nox4	-	-	C	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
ENCJOHLD_00976	9.29e-222	cryZ	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
ENCJOHLD_00977	5.72e-207	-	-	-	K	-	-	-	Transcriptional regulator
ENCJOHLD_00978	2.12e-102	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2255)
ENCJOHLD_00979	3.55e-146	-	-	-	GM	-	-	-	NmrA-like family
ENCJOHLD_00980	2.63e-206	-	-	-	S	-	-	-	Alpha beta hydrolase
ENCJOHLD_00981	3.69e-169	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
ENCJOHLD_00982	2.31e-132	thgA3	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
ENCJOHLD_00983	7.51e-147	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
ENCJOHLD_00984	8.34e-36	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
ENCJOHLD_00985	8.13e-90	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
ENCJOHLD_00986	1.55e-07	-	-	-	K	-	-	-	transcriptional regulator
ENCJOHLD_00987	1.12e-273	-	-	-	S	-	-	-	membrane
ENCJOHLD_00988	6.13e-105	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
ENCJOHLD_00989	0.0	-	-	-	S	-	-	-	Zinc finger, swim domain protein
ENCJOHLD_00990	5.7e-146	-	-	-	GM	-	-	-	epimerase
ENCJOHLD_00991	1.56e-90	-	-	-	S	-	-	-	Protein of unknown function (DUF1722)
ENCJOHLD_00992	2.65e-93	spx2	-	-	P	ko:K16509	-	ko00000	ArsC family
ENCJOHLD_00993	1.25e-140	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
ENCJOHLD_00994	1.68e-176	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
ENCJOHLD_00995	0.0	nox	-	-	P	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
ENCJOHLD_00996	6.66e-235	tanA	-	-	S	-	-	-	alpha beta
ENCJOHLD_00997	6.46e-265	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
ENCJOHLD_00998	4.38e-102	-	-	-	K	-	-	-	Transcriptional regulator
ENCJOHLD_00999	1.26e-304	-	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Major Facilitator Superfamily
ENCJOHLD_01000	1.81e-309	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
ENCJOHLD_01001	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
ENCJOHLD_01002	1.51e-232	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
ENCJOHLD_01003	6.09e-281	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
ENCJOHLD_01004	5.78e-268	-	-	-	-	-	-	-	-
ENCJOHLD_01005	7.43e-119	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
ENCJOHLD_01006	1.94e-83	-	-	-	P	-	-	-	Rhodanese Homology Domain
ENCJOHLD_01007	0.0	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
ENCJOHLD_01008	2.74e-112	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
ENCJOHLD_01009	9.06e-208	drrA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
ENCJOHLD_01010	8.81e-166	drrB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
ENCJOHLD_01011	4.8e-293	-	-	-	M	-	-	-	O-Antigen ligase
ENCJOHLD_01012	8.34e-165	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
ENCJOHLD_01013	6.55e-251	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ENCJOHLD_01014	3.17e-299	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
ENCJOHLD_01015	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
ENCJOHLD_01016	2.02e-39	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
ENCJOHLD_01017	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
ENCJOHLD_01018	8.69e-230	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
ENCJOHLD_01019	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
ENCJOHLD_01020	2.51e-98	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
ENCJOHLD_01021	7.94e-218	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
ENCJOHLD_01022	3.13e-211	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
ENCJOHLD_01023	3.99e-92	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
ENCJOHLD_01024	7.1e-176	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ENCJOHLD_01025	1.3e-132	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ENCJOHLD_01026	2.69e-167	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
ENCJOHLD_01027	2.24e-126	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
ENCJOHLD_01028	2.78e-251	-	-	-	S	-	-	-	Helix-turn-helix domain
ENCJOHLD_01029	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
ENCJOHLD_01030	1.25e-39	-	-	-	M	-	-	-	Lysin motif
ENCJOHLD_01031	2.1e-150	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
ENCJOHLD_01032	1.98e-281	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
ENCJOHLD_01033	4.84e-313	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
ENCJOHLD_01034	5.57e-55	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
ENCJOHLD_01035	2.89e-291	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
ENCJOHLD_01036	9.1e-193	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
ENCJOHLD_01037	5.66e-185	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
ENCJOHLD_01038	3.65e-291	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
ENCJOHLD_01039	6.46e-109	-	-	-	-	-	-	-	-
ENCJOHLD_01040	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
ENCJOHLD_01041	4.04e-242	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ENCJOHLD_01042	3e-118	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ENCJOHLD_01043	2.03e-189	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
ENCJOHLD_01044	1.02e-209	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
ENCJOHLD_01045	3.29e-147	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
ENCJOHLD_01046	9.33e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
ENCJOHLD_01047	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
ENCJOHLD_01048	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
ENCJOHLD_01049	4.11e-251	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
ENCJOHLD_01050	1.75e-160	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
ENCJOHLD_01051	1.27e-222	-	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
ENCJOHLD_01052	1.22e-219	cpsY	-	-	K	-	-	-	Transcriptional regulator, LysR family
ENCJOHLD_01053	5.13e-292	XK27_05470	-	-	E	-	-	-	Methionine synthase
ENCJOHLD_01054	1.85e-206	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ENCJOHLD_01055	2.04e-175	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ENCJOHLD_01056	8.11e-203	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
ENCJOHLD_01057	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ENCJOHLD_01058	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
ENCJOHLD_01059	1.5e-227	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
ENCJOHLD_01060	6.84e-121	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ENCJOHLD_01061	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ENCJOHLD_01062	3.64e-217	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
ENCJOHLD_01063	2.4e-137	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
ENCJOHLD_01064	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
ENCJOHLD_01065	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
ENCJOHLD_01066	3.82e-228	-	-	-	K	-	-	-	Transcriptional regulator
ENCJOHLD_01067	3.91e-216	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
ENCJOHLD_01068	3.8e-105	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
ENCJOHLD_01069	9.17e-126	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ENCJOHLD_01070	1.07e-43	-	-	-	S	-	-	-	YozE SAM-like fold
ENCJOHLD_01071	5.1e-204	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
ENCJOHLD_01072	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ENCJOHLD_01073	1.96e-309	-	-	-	M	-	-	-	Glycosyl transferase family group 2
ENCJOHLD_01074	3.81e-64	-	-	-	-	-	-	-	-
ENCJOHLD_01075	7.91e-305	gshR1	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
ENCJOHLD_01076	1.6e-93	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
ENCJOHLD_01077	2.53e-37	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
ENCJOHLD_01078	2.06e-57	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
ENCJOHLD_01079	0.0	tarL	2.7.8.14, 2.7.8.47	-	H	ko:K18704	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
ENCJOHLD_01080	1.66e-249	tarK	2.7.8.14, 2.7.8.46, 2.7.8.47	-	H	ko:K18704,ko:K21592	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
ENCJOHLD_01081	1.47e-243	tarJ	1.1.1.137, 1.1.1.405	-	E	ko:K05352,ko:K21680	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
ENCJOHLD_01082	7.15e-165	tarI	2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21030	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
ENCJOHLD_01083	7.87e-289	-	-	-	-	-	-	-	-
ENCJOHLD_01084	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
ENCJOHLD_01085	7.79e-78	-	-	-	-	-	-	-	-
ENCJOHLD_01086	2.79e-181	-	-	-	-	-	-	-	-
ENCJOHLD_01087	2.14e-312	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
ENCJOHLD_01088	2.59e-177	XK27_00890	-	-	S	ko:K08974	-	ko00000	Domain of unknown function (DUF368)
ENCJOHLD_01089	6.02e-166	yejC	-	-	S	-	-	-	Protein of unknown function (DUF1003)
ENCJOHLD_01090	1.33e-67	XK27_08430	-	-	S	-	-	-	Staphylococcal protein of unknown function (DUF960)
ENCJOHLD_01092	6e-268	pmrB	-	-	EGP	-	-	-	Major Facilitator Superfamily
ENCJOHLD_01093	2.82e-190	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
ENCJOHLD_01094	2.37e-65	-	-	-	-	-	-	-	-
ENCJOHLD_01095	4.74e-39	-	-	-	-	-	-	-	-
ENCJOHLD_01096	2.9e-170	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
ENCJOHLD_01097	2.47e-101	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
ENCJOHLD_01098	1.11e-205	-	-	-	S	-	-	-	EDD domain protein, DegV family
ENCJOHLD_01099	1.97e-87	-	-	-	K	-	-	-	Transcriptional regulator
ENCJOHLD_01100	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
ENCJOHLD_01101	2.42e-71	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
ENCJOHLD_01102	5.37e-117	-	-	-	F	-	-	-	NUDIX domain
ENCJOHLD_01104	2.31e-174	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2087)
ENCJOHLD_01105	8.49e-92	-	-	-	S	-	-	-	LuxR family transcriptional regulator
ENCJOHLD_01106	7.51e-166	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	Chloramphenicol acetyltransferase
ENCJOHLD_01108	1.83e-91	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
ENCJOHLD_01109	2.01e-145	-	-	-	G	-	-	-	Phosphoglycerate mutase family
ENCJOHLD_01110	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
ENCJOHLD_01111	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
ENCJOHLD_01112	4.89e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
ENCJOHLD_01113	1.1e-114	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ENCJOHLD_01114	7.98e-224	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
ENCJOHLD_01115	1.65e-97	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ENCJOHLD_01116	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
ENCJOHLD_01117	5.89e-81	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
ENCJOHLD_01118	3.28e-87	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
ENCJOHLD_01119	2.44e-267	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	FAD dependent oxidoreductase
ENCJOHLD_01120	3.69e-187	-	-	-	S	-	-	-	hydrolase activity, acting on ester bonds
ENCJOHLD_01121	6.79e-249	-	-	-	-	-	-	-	-
ENCJOHLD_01122	1.9e-156	-	-	-	P	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
ENCJOHLD_01123	5.46e-157	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
ENCJOHLD_01124	8.41e-97	XK27_05710	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
ENCJOHLD_01125	1.44e-234	-	-	-	V	-	-	-	LD-carboxypeptidase
ENCJOHLD_01126	5.01e-311	-	-	-	M	ko:K07273	-	ko00000	hydrolase, family 25
ENCJOHLD_01127	1.64e-62	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
ENCJOHLD_01128	9.52e-265	mccF	-	-	V	-	-	-	LD-carboxypeptidase
ENCJOHLD_01129	1.59e-254	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
ENCJOHLD_01130	2.26e-95	-	-	-	S	-	-	-	SnoaL-like domain
ENCJOHLD_01131	1.7e-185	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
ENCJOHLD_01132	1.14e-257	-	-	-	P	-	-	-	Major Facilitator Superfamily
ENCJOHLD_01133	1.26e-61	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
ENCJOHLD_01134	4.11e-282	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
ENCJOHLD_01136	9.98e-75	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
ENCJOHLD_01137	2.12e-142	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
ENCJOHLD_01138	3.6e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
ENCJOHLD_01139	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
ENCJOHLD_01140	8.37e-231	phnT	3.6.3.30	-	P	ko:K02010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
ENCJOHLD_01141	4.86e-235	ftpB	-	-	P	ko:K02012	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
ENCJOHLD_01142	4.58e-48	ftpA	-	-	P	ko:K02011	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
ENCJOHLD_01143	3.49e-312	ftpA	-	-	P	ko:K02011	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
ENCJOHLD_01144	1.31e-109	-	-	-	T	-	-	-	Universal stress protein family
ENCJOHLD_01145	5.51e-204	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
ENCJOHLD_01146	2.45e-142	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
ENCJOHLD_01147	9.85e-240	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ENCJOHLD_01149	1.13e-165	dnaD	-	-	L	ko:K02086	-	ko00000	Replication initiation and membrane attachment
ENCJOHLD_01150	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
ENCJOHLD_01151	3.1e-289	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
ENCJOHLD_01152	2.53e-107	ypmB	-	-	S	-	-	-	protein conserved in bacteria
ENCJOHLD_01153	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
ENCJOHLD_01154	6.01e-217	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
ENCJOHLD_01155	1.1e-230	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
ENCJOHLD_01156	1.77e-262	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
ENCJOHLD_01157	8.61e-251	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
ENCJOHLD_01158	9.23e-245	galM2	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
ENCJOHLD_01159	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
ENCJOHLD_01160	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
ENCJOHLD_01161	2.06e-158	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
ENCJOHLD_01162	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
ENCJOHLD_01163	3.86e-192	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
ENCJOHLD_01164	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
ENCJOHLD_01165	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ENCJOHLD_01166	2.12e-57	-	-	-	-	-	-	-	-
ENCJOHLD_01167	1.52e-67	-	-	-	-	-	-	-	-
ENCJOHLD_01168	5.03e-182	-	-	-	U	ko:K10716	-	ko00000,ko02000	Ion channel
ENCJOHLD_01169	1.04e-218	-	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
ENCJOHLD_01170	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
ENCJOHLD_01171	4.87e-37	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
ENCJOHLD_01172	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
ENCJOHLD_01173	1.06e-53	-	-	-	-	-	-	-	-
ENCJOHLD_01174	4e-40	-	-	-	S	-	-	-	CsbD-like
ENCJOHLD_01175	2.22e-55	-	-	-	S	-	-	-	transglycosylase associated protein
ENCJOHLD_01176	5.79e-21	-	-	-	-	-	-	-	-
ENCJOHLD_01177	1.51e-48	-	-	-	-	-	-	-	-
ENCJOHLD_01178	1.79e-211	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
ENCJOHLD_01179	3.92e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
ENCJOHLD_01180	3.05e-99	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
ENCJOHLD_01181	4.09e-106	tspO	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	TspO/MBR family
ENCJOHLD_01182	2.05e-55	-	-	-	-	-	-	-	-
ENCJOHLD_01183	3.16e-64	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
ENCJOHLD_01184	9.96e-147	-	1.14.99.53	AA10	S	ko:K21713	-	ko00000,ko01000	Lytic polysaccharide mono-oxygenase, cellulose-degrading
ENCJOHLD_01185	1.69e-276	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
ENCJOHLD_01186	1.42e-39	-	-	-	-	-	-	-	-
ENCJOHLD_01187	2.1e-71	-	-	-	-	-	-	-	-
ENCJOHLD_01189	1.19e-13	-	-	-	-	-	-	-	-
ENCJOHLD_01193	9.59e-45	-	-	-	L	-	-	-	Pfam:Integrase_AP2
ENCJOHLD_01194	6.56e-193	-	-	-	O	-	-	-	Band 7 protein
ENCJOHLD_01195	0.0	-	-	-	EGP	-	-	-	Major Facilitator
ENCJOHLD_01196	6.56e-35	-	-	-	K	-	-	-	transcriptional regulator
ENCJOHLD_01197	3.11e-62	-	-	-	K	-	-	-	transcriptional regulator
ENCJOHLD_01198	2.66e-247	rsgA_2	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
ENCJOHLD_01199	4.94e-114	ykhA	-	-	I	-	-	-	Thioesterase superfamily
ENCJOHLD_01200	1.07e-206	-	-	-	K	-	-	-	LysR substrate binding domain
ENCJOHLD_01201	3.64e-162	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
ENCJOHLD_01202	1.01e-128	-	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
ENCJOHLD_01203	5.4e-174	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
ENCJOHLD_01204	1.96e-178	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
ENCJOHLD_01205	2.62e-202	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ENCJOHLD_01206	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
ENCJOHLD_01207	7.23e-93	fabZ2	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
ENCJOHLD_01208	5.25e-96	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
ENCJOHLD_01209	5.38e-290	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
ENCJOHLD_01210	1.26e-162	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
ENCJOHLD_01211	1.72e-215	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
ENCJOHLD_01212	6.16e-48	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ENCJOHLD_01213	1.97e-230	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ENCJOHLD_01214	8.55e-99	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
ENCJOHLD_01215	8.02e-230	yneE	-	-	K	-	-	-	Transcriptional regulator
ENCJOHLD_01216	2.79e-185	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
ENCJOHLD_01217	2.12e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
ENCJOHLD_01218	5.64e-152	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
ENCJOHLD_01219	1.23e-86	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
ENCJOHLD_01220	5.61e-273	hipO1	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	Peptidase family M20/M25/M40
ENCJOHLD_01221	1.62e-276	-	-	-	E	-	-	-	glutamate:sodium symporter activity
ENCJOHLD_01222	1.95e-88	ybbJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
ENCJOHLD_01223	3.53e-227	-	1.6.5.5	-	C	ko:K00344	-	ko00000,ko01000	Zinc-binding dehydrogenase
ENCJOHLD_01224	4.14e-126	entB	-	-	Q	-	-	-	Isochorismatase family
ENCJOHLD_01225	4.82e-183	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
ENCJOHLD_01226	1.79e-287	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
ENCJOHLD_01227	1.51e-140	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
ENCJOHLD_01228	6.06e-159	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
ENCJOHLD_01229	1.42e-224	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ENCJOHLD_01230	8.08e-135	trpG	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Peptidase C26
ENCJOHLD_01231	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Anthranilate synthase component I, N terminal region
ENCJOHLD_01233	0.0	XK27_00765	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
ENCJOHLD_01234	2.05e-179	ecsA_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
ENCJOHLD_01235	1.1e-112	-	-	-	-	-	-	-	-
ENCJOHLD_01236	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
ENCJOHLD_01237	1.03e-66	-	-	-	-	-	-	-	-
ENCJOHLD_01238	3.15e-78	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
ENCJOHLD_01239	1.57e-179	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
ENCJOHLD_01240	2.24e-123	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ENCJOHLD_01241	9.99e-53	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
ENCJOHLD_01242	1.6e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
ENCJOHLD_01243	5.23e-291	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ENCJOHLD_01244	1.46e-77	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
ENCJOHLD_01245	6.32e-297	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
ENCJOHLD_01246	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
ENCJOHLD_01247	4.49e-167	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
ENCJOHLD_01248	3.33e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ENCJOHLD_01249	1.79e-243	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
ENCJOHLD_01250	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ENCJOHLD_01251	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
ENCJOHLD_01252	7.09e-76	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
ENCJOHLD_01253	1.61e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
ENCJOHLD_01254	2.61e-160	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
ENCJOHLD_01255	2.22e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
ENCJOHLD_01256	9.9e-209	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
ENCJOHLD_01257	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
ENCJOHLD_01258	1.62e-173	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
ENCJOHLD_01259	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ENCJOHLD_01260	1.49e-224	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ENCJOHLD_01261	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ENCJOHLD_01262	5.04e-278	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ENCJOHLD_01263	3.93e-41	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
ENCJOHLD_01264	6.96e-145	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
ENCJOHLD_01265	2.38e-72	-	-	-	-	-	-	-	-
ENCJOHLD_01266	1.36e-136	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
ENCJOHLD_01267	3.8e-224	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
ENCJOHLD_01268	7.11e-135	opuCB	-	-	E	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
ENCJOHLD_01269	4.51e-284	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
ENCJOHLD_01270	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
ENCJOHLD_01271	5.28e-100	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
ENCJOHLD_01272	4.49e-192	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
ENCJOHLD_01273	7.79e-205	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
ENCJOHLD_01274	7.55e-44	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
ENCJOHLD_01275	3.99e-313	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
ENCJOHLD_01276	4.82e-194	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ENCJOHLD_01277	5.46e-89	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ENCJOHLD_01278	1.7e-96	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
ENCJOHLD_01279	1.43e-129	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ENCJOHLD_01280	6.04e-249	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
ENCJOHLD_01281	2.33e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
ENCJOHLD_01282	4.62e-70	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
ENCJOHLD_01283	1.55e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
ENCJOHLD_01284	6.69e-124	-	-	-	K	-	-	-	Transcriptional regulator
ENCJOHLD_01285	9.81e-27	-	-	-	-	-	-	-	-
ENCJOHLD_01288	2.97e-41	-	-	-	-	-	-	-	-
ENCJOHLD_01289	1.87e-74	-	-	-	-	-	-	-	-
ENCJOHLD_01290	3.55e-127	-	-	-	S	-	-	-	Protein conserved in bacteria
ENCJOHLD_01291	1.34e-232	-	-	-	-	-	-	-	-
ENCJOHLD_01292	1.77e-205	-	-	-	-	-	-	-	-
ENCJOHLD_01293	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
ENCJOHLD_01294	7.79e-85	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
ENCJOHLD_01295	2.29e-225	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ENCJOHLD_01296	1.83e-177	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
ENCJOHLD_01297	1.44e-31	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
ENCJOHLD_01298	6.68e-89	yqhL	-	-	P	-	-	-	Rhodanese-like protein
ENCJOHLD_01299	5.43e-140	pepE	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
ENCJOHLD_01300	2.6e-231	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
ENCJOHLD_01301	6.33e-46	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
ENCJOHLD_01302	2.47e-153	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
ENCJOHLD_01303	3.24e-132	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ENCJOHLD_01304	5.33e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
ENCJOHLD_01305	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
ENCJOHLD_01306	0.0	-	-	-	S	-	-	-	membrane
ENCJOHLD_01307	1.09e-07	-	-	-	L	ko:K07487	-	ko00000	Transposase
ENCJOHLD_01308	1.71e-87	gcsH1	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Glycine cleavage H-protein
ENCJOHLD_01309	1.01e-225	-	-	-	-	-	-	-	-
ENCJOHLD_01310	6.88e-170	-	-	-	-	-	-	-	-
ENCJOHLD_01311	0.0	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
ENCJOHLD_01312	2.03e-75	-	-	-	-	-	-	-	-
ENCJOHLD_01313	9.17e-285	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ENCJOHLD_01314	2.55e-100	-	-	-	S	ko:K02348	-	ko00000	GNAT family
ENCJOHLD_01315	1.24e-99	-	-	-	K	-	-	-	Transcriptional regulator
ENCJOHLD_01316	9.59e-288	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
ENCJOHLD_01317	6.01e-51	-	-	-	-	-	-	-	-
ENCJOHLD_01319	1.04e-35	-	-	-	-	-	-	-	-
ENCJOHLD_01320	8.05e-33	-	-	-	U	-	-	-	Preprotein translocase subunit SecB
ENCJOHLD_01321	5.3e-265	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
ENCJOHLD_01322	9.24e-180	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
ENCJOHLD_01323	3.14e-190	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
ENCJOHLD_01324	5.09e-263	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
ENCJOHLD_01325	4.3e-124	-	-	-	K	-	-	-	Cupin domain
ENCJOHLD_01326	8.08e-110	-	-	-	S	-	-	-	ASCH
ENCJOHLD_01327	1.88e-111	-	-	-	K	-	-	-	GNAT family
ENCJOHLD_01328	2.14e-117	-	-	-	K	-	-	-	acetyltransferase
ENCJOHLD_01329	2.06e-30	-	-	-	-	-	-	-	-
ENCJOHLD_01330	5.05e-79	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
ENCJOHLD_01331	1.85e-208	-	-	-	V	ko:K01990,ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
ENCJOHLD_01332	1.08e-243	-	-	-	-	-	-	-	-
ENCJOHLD_01333	0.0	acdH	1.1.1.1, 1.2.1.10, 1.2.1.87	-	C	ko:K04072,ko:K13922	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
ENCJOHLD_01334	8.16e-207	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
ENCJOHLD_01336	2.36e-305	xylP1	-	-	G	-	-	-	MFS/sugar transport protein
ENCJOHLD_01337	4.09e-170	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
ENCJOHLD_01338	3.48e-40	-	-	-	-	-	-	-	-
ENCJOHLD_01339	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
ENCJOHLD_01340	6.4e-54	-	-	-	-	-	-	-	-
ENCJOHLD_01341	1.54e-123	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
ENCJOHLD_01342	5.83e-225	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
ENCJOHLD_01343	1.45e-79	-	-	-	S	-	-	-	CHY zinc finger
ENCJOHLD_01344	1.06e-143	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
ENCJOHLD_01345	7.98e-158	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ENCJOHLD_01346	5.18e-115	metP_2	-	-	U	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
ENCJOHLD_01347	5.67e-187	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ENCJOHLD_01348	2.25e-286	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
ENCJOHLD_01349	1.1e-280	-	-	-	-	-	-	-	-
ENCJOHLD_01350	8.13e-199	tagG	-	-	U	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
ENCJOHLD_01351	9.42e-258	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
ENCJOHLD_01352	1.13e-58	-	-	-	-	-	-	-	-
ENCJOHLD_01353	1.18e-121	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
ENCJOHLD_01354	0.0	-	-	-	P	-	-	-	Major Facilitator Superfamily
ENCJOHLD_01355	3.5e-307	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
ENCJOHLD_01356	3.66e-226	hicD1	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
ENCJOHLD_01357	8.95e-60	-	-	-	-	-	-	-	-
ENCJOHLD_01358	1.05e-132	zmp1	-	-	O	-	-	-	Zinc-dependent metalloprotease
ENCJOHLD_01359	1.19e-153	rpiA2	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
ENCJOHLD_01360	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
ENCJOHLD_01361	5.34e-72	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
ENCJOHLD_01362	1.31e-124	yxkA	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
ENCJOHLD_01363	1.61e-294	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
ENCJOHLD_01364	8.37e-108	-	-	-	K	-	-	-	Winged helix-turn-helix transcription repressor, HrcA DNA-binding
ENCJOHLD_01365	2.16e-103	-	-	-	-	-	-	-	-
ENCJOHLD_01366	2.43e-103	accB3	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
ENCJOHLD_01367	4.27e-223	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
ENCJOHLD_01368	2.82e-206	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
ENCJOHLD_01369	1.17e-101	-	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA-DNA hybrid ribonuclease activity
ENCJOHLD_01370	0.0	proWX	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
ENCJOHLD_01371	2.7e-230	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
ENCJOHLD_01372	0.0	gshR	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
ENCJOHLD_01373	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ENCJOHLD_01374	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
ENCJOHLD_01375	2.14e-174	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
ENCJOHLD_01376	0.0	-	-	-	M	-	-	-	domain protein
ENCJOHLD_01377	2.11e-76	-	-	-	M	-	-	-	dTDP-4-dehydrorhamnose reductase activity
ENCJOHLD_01378	7.12e-226	-	-	-	-	-	-	-	-
ENCJOHLD_01379	6.97e-45	-	-	-	-	-	-	-	-
ENCJOHLD_01380	5.32e-51	-	-	-	-	-	-	-	-
ENCJOHLD_01381	9.2e-154	lacA	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
ENCJOHLD_01382	1.68e-257	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
ENCJOHLD_01383	4.15e-188	-	3.1.3.102, 3.1.3.104, 3.1.3.23	-	G	ko:K07757,ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
ENCJOHLD_01384	2.35e-212	-	-	-	K	-	-	-	Transcriptional regulator
ENCJOHLD_01385	8.38e-192	-	-	-	S	-	-	-	hydrolase
ENCJOHLD_01386	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
ENCJOHLD_01387	9.82e-262	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
ENCJOHLD_01390	1.09e-149	-	-	-	-	-	-	-	-
ENCJOHLD_01391	1.22e-36	-	-	-	-	-	-	-	-
ENCJOHLD_01392	2.23e-24	plnA	-	-	-	-	-	-	-
ENCJOHLD_01393	2.08e-301	plnB	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
ENCJOHLD_01394	2.48e-172	sppR	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
ENCJOHLD_01395	1.05e-173	plnD	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
ENCJOHLD_01396	1.35e-165	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
ENCJOHLD_01397	1.93e-31	plnF	-	-	-	-	-	-	-
ENCJOHLD_01398	8.82e-32	-	-	-	-	-	-	-	-
ENCJOHLD_01399	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
ENCJOHLD_01400	1.49e-309	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
ENCJOHLD_01401	3.26e-124	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
ENCJOHLD_01402	5.04e-155	plnU	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
ENCJOHLD_01403	2.75e-145	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
ENCJOHLD_01404	3.34e-147	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
ENCJOHLD_01405	1.85e-40	-	-	-	-	-	-	-	-
ENCJOHLD_01406	0.0	-	-	-	L	-	-	-	DNA helicase
ENCJOHLD_01407	3.54e-182	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
ENCJOHLD_01408	8.19e-244	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
ENCJOHLD_01409	2.69e-166	-	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
ENCJOHLD_01410	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
ENCJOHLD_01411	9.68e-34	-	-	-	-	-	-	-	-
ENCJOHLD_01412	7.17e-99	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
ENCJOHLD_01413	0.0	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
ENCJOHLD_01414	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
ENCJOHLD_01415	4.21e-210	-	-	-	GK	-	-	-	ROK family
ENCJOHLD_01416	9.75e-175	yecA	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
ENCJOHLD_01417	5.68e-242	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ENCJOHLD_01418	4.1e-261	-	-	-	-	-	-	-	-
ENCJOHLD_01419	5.08e-194	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
ENCJOHLD_01420	1.36e-214	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
ENCJOHLD_01421	1.32e-288	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
ENCJOHLD_01422	1.82e-226	-	-	-	-	-	-	-	-
ENCJOHLD_01423	1.24e-170	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
ENCJOHLD_01424	3.74e-204	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
ENCJOHLD_01425	4.64e-92	-	-	-	F	-	-	-	DNA mismatch repair protein MutT
ENCJOHLD_01426	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ENCJOHLD_01427	4.08e-270	-	-	-	EGP	ko:K02030	-	ko00000,ko00002,ko02000	Drug resistance transporter Bcr CflA subfamily
ENCJOHLD_01428	6.64e-187	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
ENCJOHLD_01429	1.6e-127	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
ENCJOHLD_01430	2.5e-203	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
ENCJOHLD_01431	6.87e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
ENCJOHLD_01432	5.32e-208	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ENCJOHLD_01433	1.9e-230	-	-	-	S	ko:K06889	-	ko00000	Prolyl oligopeptidase family
ENCJOHLD_01434	8.05e-166	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
ENCJOHLD_01435	6.39e-169	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
ENCJOHLD_01436	2.77e-55	-	-	-	S	-	-	-	ankyrin repeats
ENCJOHLD_01437	5.3e-49	-	-	-	-	-	-	-	-
ENCJOHLD_01438	1.96e-189	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
ENCJOHLD_01439	3.28e-298	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ENCJOHLD_01440	9.06e-193	bla1	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
ENCJOHLD_01441	3.26e-228	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ENCJOHLD_01442	1.15e-235	-	-	-	S	-	-	-	DUF218 domain
ENCJOHLD_01443	7.12e-178	-	-	-	-	-	-	-	-
ENCJOHLD_01444	4.15e-191	yxeH	-	-	S	-	-	-	hydrolase
ENCJOHLD_01445	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
ENCJOHLD_01446	6.05e-198	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
ENCJOHLD_01447	2.87e-101	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
ENCJOHLD_01448	2.96e-89	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
ENCJOHLD_01449	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
ENCJOHLD_01450	5.84e-312	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ENCJOHLD_01451	2.28e-290	sdaC	-	-	E	ko:K03837	-	ko00000,ko02000	amino acid
ENCJOHLD_01452	1.25e-157	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
ENCJOHLD_01453	2.81e-202	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
ENCJOHLD_01454	1.89e-169	-	-	-	S	-	-	-	YheO-like PAS domain
ENCJOHLD_01455	2.41e-37	-	-	-	-	-	-	-	-
ENCJOHLD_01456	2.08e-302	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ENCJOHLD_01457	6.26e-306	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ENCJOHLD_01458	1.91e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
ENCJOHLD_01459	1.49e-273	-	-	-	J	-	-	-	translation release factor activity
ENCJOHLD_01460	3.14e-164	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
ENCJOHLD_01461	5.35e-121	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
ENCJOHLD_01462	1.13e-194	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
ENCJOHLD_01463	1.84e-189	-	-	-	-	-	-	-	-
ENCJOHLD_01464	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
ENCJOHLD_01465	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
ENCJOHLD_01466	9.32e-81	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
ENCJOHLD_01467	4.11e-274	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ENCJOHLD_01468	2.58e-85	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
ENCJOHLD_01469	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
ENCJOHLD_01470	1.37e-248	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	ABC transporter, substratebinding protein
ENCJOHLD_01471	4.3e-202	-	-	-	U	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
ENCJOHLD_01472	2.02e-171	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
ENCJOHLD_01473	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
ENCJOHLD_01474	1.51e-259	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
ENCJOHLD_01475	9.93e-242	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ENCJOHLD_01476	1.38e-293	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ENCJOHLD_01477	2.36e-166	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
ENCJOHLD_01478	4.47e-276	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine
ENCJOHLD_01479	3.07e-240	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ENCJOHLD_01480	5.3e-110	queT	-	-	S	-	-	-	QueT transporter
ENCJOHLD_01481	4.87e-148	-	-	-	S	-	-	-	(CBS) domain
ENCJOHLD_01482	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
ENCJOHLD_01483	2.79e-226	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
ENCJOHLD_01484	1.43e-129	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
ENCJOHLD_01485	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ENCJOHLD_01486	0.0	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
ENCJOHLD_01487	7.72e-57	yabO	-	-	J	-	-	-	S4 domain protein
ENCJOHLD_01489	2.02e-83	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
ENCJOHLD_01490	1.07e-103	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
ENCJOHLD_01491	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
ENCJOHLD_01492	4.3e-124	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
ENCJOHLD_01493	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ENCJOHLD_01494	1.93e-209	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ENCJOHLD_01495	5.33e-243	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ENCJOHLD_01496	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
ENCJOHLD_01497	7.98e-80	-	-	-	M	-	-	-	Lysin motif
ENCJOHLD_01498	2.75e-156	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
ENCJOHLD_01499	1.13e-171	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
ENCJOHLD_01500	4.87e-156	vex2	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
ENCJOHLD_01501	1.84e-295	vex3	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
ENCJOHLD_01502	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
ENCJOHLD_01503	8.31e-139	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
ENCJOHLD_01504	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
ENCJOHLD_01505	1.17e-135	-	-	-	K	-	-	-	transcriptional regulator
ENCJOHLD_01506	2.04e-158	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
ENCJOHLD_01507	1.49e-63	-	-	-	-	-	-	-	-
ENCJOHLD_01508	0.0	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
ENCJOHLD_01509	1.76e-236	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
ENCJOHLD_01510	2.87e-56	-	-	-	-	-	-	-	-
ENCJOHLD_01511	3.35e-75	-	-	-	-	-	-	-	-
ENCJOHLD_01512	6.86e-311	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
ENCJOHLD_01513	1.96e-167	yidA	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
ENCJOHLD_01514	2.42e-65	-	-	-	-	-	-	-	-
ENCJOHLD_01515	2.31e-166	rrp2	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
ENCJOHLD_01516	0.0	hpk2	-	-	T	-	-	-	Histidine kinase
ENCJOHLD_01517	2.2e-86	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
ENCJOHLD_01518	0.0	ydiC	-	-	EGP	-	-	-	Major Facilitator
ENCJOHLD_01519	1.55e-55	-	-	-	-	-	-	-	-
ENCJOHLD_01520	2.81e-55	-	-	-	-	-	-	-	-
ENCJOHLD_01521	2.6e-149	-	-	-	-	-	-	-	-
ENCJOHLD_01522	4.02e-301	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
ENCJOHLD_01523	5.2e-156	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
ENCJOHLD_01524	8.9e-96	ywnA	-	-	K	-	-	-	Transcriptional regulator
ENCJOHLD_01525	7.84e-92	-	-	-	-	-	-	-	-
ENCJOHLD_01526	6.2e-129	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
ENCJOHLD_01527	2.6e-185	-	-	-	-	-	-	-	-
ENCJOHLD_01528	0.0	pts5ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
ENCJOHLD_01529	0.0	pts4ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
ENCJOHLD_01530	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
ENCJOHLD_01531	1.68e-166	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
ENCJOHLD_01532	2.21e-56	-	-	-	-	-	-	-	-
ENCJOHLD_01533	7.55e-58	-	-	-	S	-	-	-	Protein of unknown function (DUF2089)
ENCJOHLD_01534	1.27e-181	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
ENCJOHLD_01535	6.72e-203	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
ENCJOHLD_01536	1.3e-211	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
ENCJOHLD_01537	5.78e-268	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
ENCJOHLD_01538	4.3e-124	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Bacterial transferase hexapeptide (six repeats)
ENCJOHLD_01539	1.82e-126	-	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
ENCJOHLD_01540	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
ENCJOHLD_01541	2.41e-106	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
ENCJOHLD_01542	2.98e-90	-	-	-	-	-	-	-	-
ENCJOHLD_01543	1.22e-125	-	-	-	-	-	-	-	-
ENCJOHLD_01544	3.43e-66	-	-	-	-	-	-	-	-
ENCJOHLD_01545	4.81e-76	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
ENCJOHLD_01546	1.21e-111	-	-	-	-	-	-	-	-
ENCJOHLD_01547	1.06e-281	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
ENCJOHLD_01548	1.53e-102	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
ENCJOHLD_01549	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
ENCJOHLD_01550	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
ENCJOHLD_01551	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
ENCJOHLD_01552	7.02e-126	-	-	-	K	-	-	-	Helix-turn-helix domain
ENCJOHLD_01553	7.88e-283	-	-	-	C	-	-	-	FAD dependent oxidoreductase
ENCJOHLD_01554	2.22e-221	-	-	-	P	-	-	-	Major Facilitator Superfamily
ENCJOHLD_01555	3.16e-170	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
ENCJOHLD_01556	2.32e-43	ygzD	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional
ENCJOHLD_01557	1.2e-91	-	-	-	-	-	-	-	-
ENCJOHLD_01558	3.68e-102	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
ENCJOHLD_01559	2.16e-201	dkgB	-	-	S	-	-	-	reductase
ENCJOHLD_01560	5.84e-115	gpo	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
ENCJOHLD_01561	1.43e-131	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC transporter permease
ENCJOHLD_01562	0.0	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
ENCJOHLD_01563	1.75e-149	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
ENCJOHLD_01565	0.0	-	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
ENCJOHLD_01566	5.66e-74	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ENCJOHLD_01567	6.41e-77	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ENCJOHLD_01568	3.81e-18	-	-	-	-	-	-	-	-
ENCJOHLD_01569	1.29e-278	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ENCJOHLD_01570	8.83e-208	fbpA	-	-	K	-	-	-	Domain of unknown function (DUF814)
ENCJOHLD_01571	1.15e-79	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
ENCJOHLD_01572	6.33e-46	-	-	-	-	-	-	-	-
ENCJOHLD_01573	2.49e-229	yghZ	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
ENCJOHLD_01574	2.73e-147	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
ENCJOHLD_01575	1.24e-259	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ENCJOHLD_01576	1.45e-278	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ENCJOHLD_01577	9.25e-103	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
ENCJOHLD_01578	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
ENCJOHLD_01579	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
ENCJOHLD_01580	1.03e-201	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
ENCJOHLD_01582	0.0	-	-	-	M	-	-	-	domain protein
ENCJOHLD_01583	5.99e-213	mleR	-	-	K	-	-	-	LysR substrate binding domain
ENCJOHLD_01584	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
ENCJOHLD_01585	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
ENCJOHLD_01586	9.92e-212	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
ENCJOHLD_01587	0.0	-	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
ENCJOHLD_01588	2.4e-230	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
ENCJOHLD_01589	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
ENCJOHLD_01590	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
ENCJOHLD_01591	1.8e-215	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
ENCJOHLD_01592	1.17e-60	ygbF	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
ENCJOHLD_01593	0.0	-	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 85
ENCJOHLD_01594	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
ENCJOHLD_01595	2.44e-267	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
ENCJOHLD_01596	0.0	malS	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Glycogen debranching enzyme, glucanotransferase domain
ENCJOHLD_01597	1.01e-190	malA	-	-	S	-	-	-	maltodextrose utilization protein MalA
ENCJOHLD_01598	2.83e-206	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
ENCJOHLD_01599	3.74e-302	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
ENCJOHLD_01600	4.69e-299	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
ENCJOHLD_01601	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
ENCJOHLD_01602	1.83e-231	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
ENCJOHLD_01603	2.65e-245	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
ENCJOHLD_01604	4e-172	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
ENCJOHLD_01605	6.76e-75	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
ENCJOHLD_01606	2.75e-131	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
ENCJOHLD_01607	9.52e-240	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
ENCJOHLD_01608	2.35e-243	dhaK2	2.7.1.28, 2.7.1.29, 4.6.1.15	-	G	ko:K00863	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	ko00000,ko00001,ko00002,ko01000	Dak1 domain
ENCJOHLD_01609	1.85e-121	XK27_02085	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
ENCJOHLD_01611	2.04e-99	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
ENCJOHLD_01612	0.0	etfA	1.3.1.108	-	C	ko:K03522,ko:K22432	-	ko00000,ko01000,ko04147	Electron transfer flavoprotein FAD-binding domain
ENCJOHLD_01613	1.39e-151	-	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
ENCJOHLD_01614	0.0	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
ENCJOHLD_01615	3.49e-217	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
ENCJOHLD_01616	7.14e-185	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
ENCJOHLD_01617	3.37e-115	-	-	-	-	-	-	-	-
ENCJOHLD_01618	3.69e-190	-	-	-	-	-	-	-	-
ENCJOHLD_01619	2.69e-183	-	-	-	-	-	-	-	-
ENCJOHLD_01620	4.14e-72	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
ENCJOHLD_01621	4.37e-167	-	-	-	K	ko:K03492	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
ENCJOHLD_01623	2.57e-128	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
ENCJOHLD_01624	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
ENCJOHLD_01625	3.28e-193	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
ENCJOHLD_01626	6.49e-268	-	-	-	C	-	-	-	Oxidoreductase
ENCJOHLD_01627	0.0	-	-	-	-	-	-	-	-
ENCJOHLD_01628	3.3e-131	-	-	-	-	-	-	-	-
ENCJOHLD_01629	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
ENCJOHLD_01630	7.84e-106	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase like
ENCJOHLD_01631	6.75e-212	-	1.1.1.65	-	C	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	ko00000,ko00001,ko01000	Aldo keto reductase
ENCJOHLD_01632	2.52e-203	morA	-	-	S	-	-	-	reductase
ENCJOHLD_01634	2.79e-274	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
ENCJOHLD_01635	3.98e-68	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
ENCJOHLD_01636	5.38e-290	-	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
ENCJOHLD_01637	3.73e-104	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
ENCJOHLD_01638	3.99e-96	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
ENCJOHLD_01639	2.57e-98	-	-	-	K	-	-	-	Transcriptional regulator
ENCJOHLD_01640	2.01e-141	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
ENCJOHLD_01641	2.92e-38	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
ENCJOHLD_01642	0.0	pacL1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
ENCJOHLD_01643	2.94e-191	-	-	-	I	-	-	-	Alpha/beta hydrolase family
ENCJOHLD_01644	4.08e-156	-	-	-	-	-	-	-	-
ENCJOHLD_01645	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
ENCJOHLD_01646	3.55e-109	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
ENCJOHLD_01647	0.0	-	-	-	L	-	-	-	HIRAN domain
ENCJOHLD_01648	1.02e-175	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
ENCJOHLD_01649	1.97e-259	thiP	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
ENCJOHLD_01650	2.68e-143	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
ENCJOHLD_01651	3.03e-191	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
ENCJOHLD_01652	3.77e-175	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
ENCJOHLD_01653	3.94e-224	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
ENCJOHLD_01654	6.38e-194	larE	-	-	S	ko:K06864	-	ko00000	NAD synthase
ENCJOHLD_01655	1.19e-170	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
ENCJOHLD_01656	6.32e-99	larC2	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Protein of unknown function DUF111
ENCJOHLD_01657	2.03e-179	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
ENCJOHLD_01658	2.65e-162	larB	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
ENCJOHLD_01659	7.9e-306	larA	5.1.2.1	-	S	ko:K22373	ko00620,map00620	ko00000,ko00001,ko01000	Domain of unknown function (DUF2088)
ENCJOHLD_01660	1.39e-156	rcfB	-	-	K	-	-	-	Crp-like helix-turn-helix domain
ENCJOHLD_01661	1.84e-235	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
ENCJOHLD_01662	9.79e-192	-	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
ENCJOHLD_01663	7.11e-165	-	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
ENCJOHLD_01664	1.67e-54	-	-	-	-	-	-	-	-
ENCJOHLD_01665	1.25e-140	ant1	2.7.7.47	-	H	ko:K00984	-	ko00000,ko01000,ko01504	Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
ENCJOHLD_01666	4.07e-05	-	-	-	-	-	-	-	-
ENCJOHLD_01667	4.85e-180	-	-	-	-	-	-	-	-
ENCJOHLD_01668	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
ENCJOHLD_01669	2.38e-99	-	-	-	-	-	-	-	-
ENCJOHLD_01670	9.06e-180	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
ENCJOHLD_01671	6.34e-215	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
ENCJOHLD_01672	6.97e-301	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
ENCJOHLD_01673	1.92e-67	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
ENCJOHLD_01674	3.14e-230	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
ENCJOHLD_01675	1.4e-162	-	-	-	S	-	-	-	DJ-1/PfpI family
ENCJOHLD_01676	7.65e-121	yfbM	-	-	K	-	-	-	FR47-like protein
ENCJOHLD_01677	4.28e-195	-	-	-	EG	-	-	-	EamA-like transporter family
ENCJOHLD_01678	1.9e-79	-	-	-	S	-	-	-	Protein of unknown function
ENCJOHLD_01679	7.44e-51	-	-	-	S	-	-	-	Protein of unknown function
ENCJOHLD_01680	0.0	fusA1	-	-	J	-	-	-	elongation factor G
ENCJOHLD_01681	6.04e-217	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
ENCJOHLD_01682	1.22e-126	-	-	-	C	-	-	-	Nitroreductase family
ENCJOHLD_01683	1.23e-228	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
ENCJOHLD_01684	3.45e-209	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ENCJOHLD_01685	2.2e-157	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
ENCJOHLD_01686	1.22e-200	ccpB	-	-	K	-	-	-	lacI family
ENCJOHLD_01687	4.16e-150	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
ENCJOHLD_01688	1.18e-225	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
ENCJOHLD_01689	8.97e-253	yhhX	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
ENCJOHLD_01690	0.0	nhaP2	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
ENCJOHLD_01691	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ENCJOHLD_01692	9.38e-139	pncA	-	-	Q	-	-	-	Isochorismatase family
ENCJOHLD_01693	2.18e-171	-	-	-	-	-	-	-	-
ENCJOHLD_01694	5e-162	skfE	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
ENCJOHLD_01695	8.34e-86	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
ENCJOHLD_01696	7.2e-61	-	-	-	S	-	-	-	Enterocin A Immunity
ENCJOHLD_01697	3.25e-223	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
ENCJOHLD_01698	0.0	pepF2	-	-	E	-	-	-	Oligopeptidase F
ENCJOHLD_01699	1.4e-95	-	-	-	K	-	-	-	Transcriptional regulator
ENCJOHLD_01700	1.86e-210	-	-	-	-	-	-	-	-
ENCJOHLD_01701	1.23e-75	-	-	-	-	-	-	-	-
ENCJOHLD_01702	4.83e-64	-	-	-	-	-	-	-	-
ENCJOHLD_01703	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
ENCJOHLD_01704	1.17e-88	-	-	-	-	-	-	-	-
ENCJOHLD_01705	1.19e-186	-	-	-	S	ko:K06889	-	ko00000	Dienelactone hydrolase family
ENCJOHLD_01706	9.89e-74	ytpP	-	-	CO	-	-	-	Thioredoxin
ENCJOHLD_01707	3.18e-261	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
ENCJOHLD_01708	3.89e-62	-	-	-	-	-	-	-	-
ENCJOHLD_01709	2.16e-63	-	-	-	-	-	-	-	-
ENCJOHLD_01710	6.94e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF2798)
ENCJOHLD_01711	4.05e-98	-	-	-	-	-	-	-	-
ENCJOHLD_01712	4.15e-78	-	-	-	-	-	-	-	-
ENCJOHLD_01713	4.26e-250	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
ENCJOHLD_01714	0.0	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Bacterial SH3 domain
ENCJOHLD_01715	1.02e-102	uspA3	-	-	T	-	-	-	universal stress protein
ENCJOHLD_01716	8.36e-202	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
ENCJOHLD_01717	2.73e-24	-	-	-	-	-	-	-	-
ENCJOHLD_01718	1.09e-55	-	-	-	S	-	-	-	zinc-ribbon domain
ENCJOHLD_01719	9.66e-97	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
ENCJOHLD_01720	4.05e-64	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
ENCJOHLD_01721	3.96e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
ENCJOHLD_01722	1.85e-285	-	-	-	M	-	-	-	Glycosyl transferases group 1
ENCJOHLD_01723	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
ENCJOHLD_01724	2.25e-206	-	-	-	S	-	-	-	Putative esterase
ENCJOHLD_01725	3.53e-169	-	-	-	K	-	-	-	Transcriptional regulator
ENCJOHLD_01726	6.74e-117	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ENCJOHLD_01727	1.67e-176	-	-	-	-	-	-	-	-
ENCJOHLD_01728	1.97e-150	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
ENCJOHLD_01729	8.05e-179	rrp8	-	-	K	-	-	-	LytTr DNA-binding domain
ENCJOHLD_01730	1.7e-118	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
ENCJOHLD_01731	1.55e-79	-	-	-	-	-	-	-	-
ENCJOHLD_01732	2.61e-96	hsp2	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
ENCJOHLD_01733	2.97e-76	-	-	-	-	-	-	-	-
ENCJOHLD_01734	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
ENCJOHLD_01735	1.18e-114	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
ENCJOHLD_01736	0.0	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
ENCJOHLD_01737	3.36e-270	yttB	-	-	EGP	-	-	-	Major Facilitator
ENCJOHLD_01738	1.92e-80	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
ENCJOHLD_01739	6.27e-220	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
ENCJOHLD_01740	4.71e-74	-	-	-	S	-	-	-	SdpI/YhfL protein family
ENCJOHLD_01741	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ENCJOHLD_01742	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	Bacterial regulatory proteins, gntR family
ENCJOHLD_01743	2.91e-277	araT2	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
ENCJOHLD_01744	1.84e-204	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ENCJOHLD_01745	3.59e-26	-	-	-	-	-	-	-	-
ENCJOHLD_01746	2.09e-169	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
ENCJOHLD_01747	5.73e-208	mleR	-	-	K	-	-	-	LysR family
ENCJOHLD_01748	1.29e-148	-	-	-	GM	-	-	-	NAD(P)H-binding
ENCJOHLD_01749	3.86e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
ENCJOHLD_01750	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
ENCJOHLD_01751	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
ENCJOHLD_01752	4.54e-216	oroP	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
ENCJOHLD_01753	6.64e-146	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ENCJOHLD_01754	1.09e-161	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
ENCJOHLD_01755	4.24e-218	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
ENCJOHLD_01756	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
ENCJOHLD_01757	1.37e-271	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
ENCJOHLD_01758	2.38e-310	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
ENCJOHLD_01759	1.42e-219	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
ENCJOHLD_01760	7.13e-123	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ENCJOHLD_01761	0.0	pucR_2	-	-	QT	ko:K09684	-	ko00000,ko03000	Purine catabolism regulatory protein-like family
ENCJOHLD_01762	4.41e-305	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
ENCJOHLD_01763	5.67e-280	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
ENCJOHLD_01764	4.71e-208	-	-	-	GM	-	-	-	NmrA-like family
ENCJOHLD_01765	1.25e-199	-	-	-	T	-	-	-	EAL domain
ENCJOHLD_01766	1.85e-121	-	-	-	-	-	-	-	-
ENCJOHLD_01767	0.0	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
ENCJOHLD_01768	3.85e-159	-	-	-	E	-	-	-	Methionine synthase
ENCJOHLD_01769	6.66e-281	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
ENCJOHLD_01770	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
ENCJOHLD_01771	1.79e-131	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ENCJOHLD_01772	1.04e-243	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
ENCJOHLD_01773	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ENCJOHLD_01774	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ENCJOHLD_01775	2.82e-163	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ENCJOHLD_01776	1.17e-55	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ENCJOHLD_01777	3.39e-168	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
ENCJOHLD_01778	3.35e-269	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ENCJOHLD_01779	3.77e-104	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ENCJOHLD_01780	7.9e-305	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
ENCJOHLD_01781	9.92e-143	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
ENCJOHLD_01782	1.16e-242	lplL	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Bacterial lipoate protein ligase C-terminus
ENCJOHLD_01783	2.04e-189	ptp3	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
ENCJOHLD_01784	3.44e-152	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
ENCJOHLD_01785	4.15e-191	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
ENCJOHLD_01786	3.7e-233	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
ENCJOHLD_01787	2.05e-178	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
ENCJOHLD_01788	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
ENCJOHLD_01789	4.76e-56	-	-	-	-	-	-	-	-
ENCJOHLD_01790	8.2e-81	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
ENCJOHLD_01791	7.89e-212	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
ENCJOHLD_01792	5.66e-189	-	-	-	-	-	-	-	-
ENCJOHLD_01793	2.7e-104	usp5	-	-	T	-	-	-	universal stress protein
ENCJOHLD_01794	1.08e-47	-	-	-	-	-	-	-	-
ENCJOHLD_01795	4.02e-95	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
ENCJOHLD_01796	1.02e-113	-	-	-	-	-	-	-	-
ENCJOHLD_01797	1.4e-65	-	-	-	-	-	-	-	-
ENCJOHLD_01798	4.79e-13	-	-	-	-	-	-	-	-
ENCJOHLD_01799	8.68e-299	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
ENCJOHLD_01800	1.16e-110	-	-	-	F	-	-	-	belongs to the nudix hydrolase family
ENCJOHLD_01801	1.52e-151	-	-	-	-	-	-	-	-
ENCJOHLD_01802	1.21e-69	-	-	-	-	-	-	-	-
ENCJOHLD_01804	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
ENCJOHLD_01805	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
ENCJOHLD_01806	1.1e-184	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
ENCJOHLD_01807	2.38e-37	-	-	-	S	-	-	-	Pentapeptide repeats (8 copies)
ENCJOHLD_01808	1.76e-143	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
ENCJOHLD_01809	5.38e-131	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
ENCJOHLD_01810	2.26e-91	-	-	-	FG	-	-	-	Scavenger mRNA decapping enzyme C-term binding
ENCJOHLD_01811	1.62e-173	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
ENCJOHLD_01812	3.94e-49	XK27_01315	-	-	S	-	-	-	Protein of unknown function (DUF2829)
ENCJOHLD_01813	6.01e-270	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
ENCJOHLD_01814	4.43e-294	-	-	-	S	-	-	-	Sterol carrier protein domain
ENCJOHLD_01815	7.54e-115	yrxA	-	-	S	ko:K07105	-	ko00000	3H domain
ENCJOHLD_01816	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ENCJOHLD_01817	2.13e-152	-	-	-	K	-	-	-	Transcriptional regulator
ENCJOHLD_01818	9.76e-234	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
ENCJOHLD_01819	4.29e-173	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
ENCJOHLD_01820	9.53e-317	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
ENCJOHLD_01821	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
ENCJOHLD_01822	0.0	pbg5	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
ENCJOHLD_01823	2.73e-73	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
ENCJOHLD_01824	1.86e-64	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
ENCJOHLD_01825	6.37e-169	gntR	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
ENCJOHLD_01826	1.4e-181	epsV	-	-	S	-	-	-	glycosyl transferase family 2
ENCJOHLD_01827	1.75e-156	pgm7	-	-	G	-	-	-	Phosphoglycerate mutase family
ENCJOHLD_01828	7.63e-107	-	-	-	-	-	-	-	-
ENCJOHLD_01829	5.06e-196	-	-	-	S	-	-	-	hydrolase
ENCJOHLD_01830	1.51e-235	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ENCJOHLD_01831	2.8e-204	-	-	-	EG	-	-	-	EamA-like transporter family
ENCJOHLD_01832	4.12e-226	serA1	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
ENCJOHLD_01833	3.78e-132	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
ENCJOHLD_01834	0.0	-	-	-	-	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	-
ENCJOHLD_01835	1.17e-101	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
ENCJOHLD_01836	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
ENCJOHLD_01837	0.0	-	-	-	M	-	-	-	Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
ENCJOHLD_01838	4.3e-44	-	-	-	-	-	-	-	-
ENCJOHLD_01839	2.89e-165	aroC1	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Type I 3-dehydroquinase
ENCJOHLD_01840	0.0	ycaM	-	-	E	-	-	-	amino acid
ENCJOHLD_01841	2.45e-101	-	-	-	K	-	-	-	Winged helix DNA-binding domain
ENCJOHLD_01842	1.42e-212	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
ENCJOHLD_01843	5.11e-208	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
ENCJOHLD_01844	1.3e-209	-	-	-	K	-	-	-	Transcriptional regulator
ENCJOHLD_01857	3.26e-119	-	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Phosphoribosyl transferase domain
ENCJOHLD_01858	5.46e-238	-	-	-	P	ko:K06901	-	ko00000,ko02000	secondary active sulfate transmembrane transporter activity
ENCJOHLD_01859	1.25e-124	-	-	-	-	-	-	-	-
ENCJOHLD_01860	1.58e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
ENCJOHLD_01861	2.07e-200	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
ENCJOHLD_01863	1.33e-292	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
ENCJOHLD_01864	2.53e-240	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
ENCJOHLD_01865	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
ENCJOHLD_01866	7.89e-216	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
ENCJOHLD_01867	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
ENCJOHLD_01868	3.21e-155	-	-	-	-	-	-	-	-
ENCJOHLD_01869	2.78e-273	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ENCJOHLD_01870	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
ENCJOHLD_01871	1.44e-294	-	-	-	N	-	-	-	Cell shape-determining protein MreB
ENCJOHLD_01872	5.9e-255	-	-	-	S	-	-	-	Pfam Methyltransferase
ENCJOHLD_01873	0.0	tagE2	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
ENCJOHLD_01874	0.0	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
ENCJOHLD_01875	9.32e-40	-	-	-	-	-	-	-	-
ENCJOHLD_01876	3.03e-122	mraW1	-	-	J	-	-	-	Putative rRNA methylase
ENCJOHLD_01877	2.95e-160	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
ENCJOHLD_01878	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
ENCJOHLD_01879	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
ENCJOHLD_01880	5.04e-176	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
ENCJOHLD_01881	5.24e-194	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ENCJOHLD_01882	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
ENCJOHLD_01883	2.52e-108	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
ENCJOHLD_01884	1.24e-259	ugpC	3.6.3.20	-	E	ko:K05816,ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the ABC transporter superfamily
ENCJOHLD_01885	3.93e-222	ugpA	-	-	U	ko:K02025,ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
ENCJOHLD_01886	3.05e-193	ugpE	-	-	G	ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
ENCJOHLD_01887	6.59e-72	ugpB	-	-	G	ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
ENCJOHLD_01888	4.7e-224	ugpB	-	-	G	ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
ENCJOHLD_01889	3.67e-147	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
ENCJOHLD_01890	2.07e-155	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
ENCJOHLD_01891	3.55e-72	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
ENCJOHLD_01892	1.48e-315	XK27_06930	-	-	V	ko:K01421	-	ko00000	domain protein
ENCJOHLD_01894	4.24e-163	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
ENCJOHLD_01895	3.06e-201	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
ENCJOHLD_01896	2.57e-226	-	-	-	K	ko:K01990	-	ko00000,ko00002,ko02000	LytTr DNA-binding domain
ENCJOHLD_01898	6.68e-196	mrsA1	1.8.4.11	-	O	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ENCJOHLD_01899	5.2e-85	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
ENCJOHLD_01900	1.64e-151	-	-	-	GM	-	-	-	NAD(P)H-binding
ENCJOHLD_01901	9.36e-205	ydeD	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
ENCJOHLD_01902	1.14e-190	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
ENCJOHLD_01903	7.83e-140	-	-	-	-	-	-	-	-
ENCJOHLD_01904	8.83e-285	pltK	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
ENCJOHLD_01905	9.01e-179	agrA	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
ENCJOHLD_01906	5.37e-74	-	-	-	-	-	-	-	-
ENCJOHLD_01907	4.56e-78	-	-	-	-	-	-	-	-
ENCJOHLD_01908	1.06e-146	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
ENCJOHLD_01909	2.2e-111	ohrR	-	-	K	ko:K18906	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
ENCJOHLD_01910	8.82e-119	-	-	-	-	-	-	-	-
ENCJOHLD_01911	7.12e-62	-	-	-	-	-	-	-	-
ENCJOHLD_01912	0.0	uvrA2	-	-	L	-	-	-	ABC transporter
ENCJOHLD_01914	2.27e-268	-	-	-	S	-	-	-	Phage integrase family
ENCJOHLD_01920	1.92e-101	-	-	-	K	-	-	-	Peptidase S24-like
ENCJOHLD_01921	2.06e-46	-	-	-	S	-	-	-	sequence-specific DNA binding
ENCJOHLD_01922	2.77e-86	-	-	-	S	-	-	-	DNA binding
ENCJOHLD_01923	2.69e-77	-	-	-	S	-	-	-	Domain of unknown function (DUF771)
ENCJOHLD_01926	3.04e-29	-	-	-	-	-	-	-	-
ENCJOHLD_01928	9.04e-120	-	-	-	S	-	-	-	Bacteriophage Mu Gam like protein
ENCJOHLD_01929	1.89e-149	-	-	-	S	-	-	-	AAA domain
ENCJOHLD_01930	2.52e-133	-	-	-	S	-	-	-	Protein of unknown function (DUF669)
ENCJOHLD_01931	8.39e-167	-	-	-	S	-	-	-	Putative HNHc nuclease
ENCJOHLD_01932	2.18e-93	-	-	-	L	-	-	-	DnaD domain protein
ENCJOHLD_01933	9.77e-50	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
ENCJOHLD_01934	3.79e-88	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
ENCJOHLD_01936	2.49e-63	-	-	-	-	-	-	-	-
ENCJOHLD_01937	1.01e-20	-	-	-	-	-	-	-	-
ENCJOHLD_01940	4.05e-34	-	-	-	S	-	-	-	YopX protein
ENCJOHLD_01941	0.000334	-	-	-	S	-	-	-	Protein of unknown function (DUF1642)
ENCJOHLD_01943	3.02e-21	-	-	-	-	-	-	-	-
ENCJOHLD_01944	7.39e-98	-	-	-	S	-	-	-	Transcriptional regulator, RinA family
ENCJOHLD_01946	1.1e-16	-	-	-	V	-	-	-	HNH nucleases
ENCJOHLD_01947	3.87e-115	-	-	-	L	-	-	-	HNH nucleases
ENCJOHLD_01948	4.52e-101	-	-	-	L	-	-	-	Phage terminase, small subunit
ENCJOHLD_01949	0.0	-	-	-	S	-	-	-	Phage Terminase
ENCJOHLD_01951	2.05e-235	-	-	-	S	-	-	-	Phage portal protein
ENCJOHLD_01952	2.98e-101	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
ENCJOHLD_01953	8.53e-89	-	-	-	S	-	-	-	Phage capsid family
ENCJOHLD_01954	1.6e-66	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
ENCJOHLD_01955	4.24e-33	-	-	-	S	-	-	-	Phage head-tail joining protein
ENCJOHLD_01956	6.59e-51	-	-	-	-	-	-	-	-
ENCJOHLD_01958	1.22e-89	-	-	-	S	-	-	-	Phage tail tube protein
ENCJOHLD_01960	5.58e-06	-	-	-	-	-	-	-	-
ENCJOHLD_01961	0.0	-	-	-	S	-	-	-	peptidoglycan catabolic process
ENCJOHLD_01962	3.16e-297	-	-	-	S	-	-	-	Phage tail protein
ENCJOHLD_01963	0.0	-	-	-	S	-	-	-	Phage minor structural protein
ENCJOHLD_01964	2.94e-125	-	-	-	-	-	-	-	-
ENCJOHLD_01967	1.8e-62	-	-	-	-	-	-	-	-
ENCJOHLD_01968	7.61e-208	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
ENCJOHLD_01969	4.53e-50	-	-	-	S	-	-	-	Haemolysin XhlA
ENCJOHLD_01971	2.15e-27	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
ENCJOHLD_01973	4.29e-87	-	-	-	-	-	-	-	-
ENCJOHLD_01974	9.03e-16	-	-	-	-	-	-	-	-
ENCJOHLD_01975	3.89e-237	-	-	-	-	-	-	-	-
ENCJOHLD_01976	4.91e-117	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
ENCJOHLD_01977	8.01e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1516)
ENCJOHLD_01978	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
ENCJOHLD_01979	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ENCJOHLD_01980	0.0	-	-	-	S	-	-	-	Protein conserved in bacteria
ENCJOHLD_01981	7.32e-292	sat	2.7.7.4	-	H	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
ENCJOHLD_01982	2.24e-146	cysC	2.7.1.25	-	F	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
ENCJOHLD_01983	5.68e-233	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
ENCJOHLD_01984	0.0	astA	2.8.2.22	-	M	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
ENCJOHLD_01985	0.0	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
ENCJOHLD_01986	2.69e-316	dinF	-	-	V	-	-	-	MatE
ENCJOHLD_01987	1.79e-42	-	-	-	-	-	-	-	-
ENCJOHLD_01990	7.02e-103	yybD	-	-	S	ko:K02348	-	ko00000	Acetyltransferase (GNAT) domain
ENCJOHLD_01991	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
ENCJOHLD_01992	3.81e-105	-	-	-	-	-	-	-	-
ENCJOHLD_01993	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
ENCJOHLD_01994	6.25e-138	-	-	-	-	-	-	-	-
ENCJOHLD_01995	0.0	celR	-	-	K	-	-	-	PRD domain
ENCJOHLD_01996	1.34e-104	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
ENCJOHLD_01997	2.37e-68	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
ENCJOHLD_01998	4.9e-64	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
ENCJOHLD_01999	1.02e-285	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
ENCJOHLD_02000	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
ENCJOHLD_02001	1.14e-191	-	-	-	EGP	ko:K08218	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Major facilitator Superfamily
ENCJOHLD_02002	1.1e-70	-	-	-	EGP	ko:K08218	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Major facilitator Superfamily
ENCJOHLD_02003	1.72e-148	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
ENCJOHLD_02004	1.65e-46	dltC2	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ENCJOHLD_02005	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	Alanine-glyoxylate amino-transferase
ENCJOHLD_02006	3.29e-132	argO	-	-	S	ko:K06895	-	ko00000,ko02000	LysE type translocator
ENCJOHLD_02007	9.65e-272	arcT	-	-	E	-	-	-	Aminotransferase
ENCJOHLD_02008	2.07e-102	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
ENCJOHLD_02009	2.43e-18	-	-	-	-	-	-	-	-
ENCJOHLD_02010	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
ENCJOHLD_02011	9.94e-71	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
ENCJOHLD_02012	5e-293	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
ENCJOHLD_02013	0.0	yhaN	-	-	L	-	-	-	AAA domain
ENCJOHLD_02014	1.03e-240	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
ENCJOHLD_02015	2.24e-277	-	-	-	-	-	-	-	-
ENCJOHLD_02016	4.86e-233	-	-	-	M	-	-	-	Peptidase family S41
ENCJOHLD_02017	1.9e-148	-	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
ENCJOHLD_02018	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
ENCJOHLD_02019	9.2e-317	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
ENCJOHLD_02020	2.09e-85	-	-	-	-	-	-	-	-
ENCJOHLD_02021	5.15e-16	-	-	-	-	-	-	-	-
ENCJOHLD_02022	5.61e-54	pcaC	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
ENCJOHLD_02023	4.83e-31	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
ENCJOHLD_02024	5.98e-85	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
ENCJOHLD_02025	3.31e-281	-	-	-	S	-	-	-	Membrane
ENCJOHLD_02026	1.04e-59	-	-	-	S	-	-	-	Protein of unknown function (DUF3781)
ENCJOHLD_02027	5.35e-139	yoaZ	-	-	S	-	-	-	intracellular protease amidase
ENCJOHLD_02028	1.35e-55	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
ENCJOHLD_02029	9.66e-77	-	-	-	-	-	-	-	-
ENCJOHLD_02030	2.06e-81	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
ENCJOHLD_02031	5.31e-66	-	-	-	K	-	-	-	Helix-turn-helix domain
ENCJOHLD_02032	9.09e-260	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
ENCJOHLD_02033	3.64e-47	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
ENCJOHLD_02034	1.44e-148	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
ENCJOHLD_02035	8.09e-142	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
ENCJOHLD_02036	1.93e-139	-	-	-	GM	-	-	-	NAD(P)H-binding
ENCJOHLD_02037	5.35e-102	-	-	-	GM	-	-	-	SnoaL-like domain
ENCJOHLD_02038	0.0	qacA	-	-	EGP	-	-	-	Fungal trichothecene efflux pump (TRI12)
ENCJOHLD_02039	2.52e-85	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
ENCJOHLD_02040	7.9e-136	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
ENCJOHLD_02041	1.34e-05	-	-	-	L	ko:K07483	-	ko00000	transposase activity
ENCJOHLD_02042	8.53e-45	-	-	-	L	ko:K07483	-	ko00000	transposase activity
ENCJOHLD_02044	6.79e-53	-	-	-	-	-	-	-	-
ENCJOHLD_02045	5.06e-168	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ENCJOHLD_02046	9.26e-233	ydbI	-	-	K	-	-	-	AI-2E family transporter
ENCJOHLD_02047	7.62e-270	xylR	-	-	GK	-	-	-	ROK family
ENCJOHLD_02048	4.93e-149	-	-	-	-	-	-	-	-
ENCJOHLD_02049	3.66e-295	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
ENCJOHLD_02050	2e-211	-	-	-	-	-	-	-	-
ENCJOHLD_02051	1.94e-258	pkn2	-	-	KLT	-	-	-	Protein tyrosine kinase
ENCJOHLD_02052	5.03e-37	-	-	-	S	-	-	-	Protein of unknown function (DUF4064)
ENCJOHLD_02053	2.47e-125	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
ENCJOHLD_02054	9.69e-99	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
ENCJOHLD_02056	5.01e-71	-	-	-	-	-	-	-	-
ENCJOHLD_02057	1.37e-140	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
ENCJOHLD_02058	5.93e-73	-	-	-	S	-	-	-	branched-chain amino acid
ENCJOHLD_02059	2.05e-167	-	-	-	E	-	-	-	branched-chain amino acid
ENCJOHLD_02060	1.66e-116	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
ENCJOHLD_02061	4.4e-304	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
ENCJOHLD_02062	5.61e-273	hpk31	-	-	T	-	-	-	Histidine kinase
ENCJOHLD_02063	1.14e-159	vanR	-	-	K	-	-	-	response regulator
ENCJOHLD_02064	9.76e-159	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
ENCJOHLD_02065	2.22e-206	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
ENCJOHLD_02066	3.49e-270	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
ENCJOHLD_02067	3.49e-160	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
ENCJOHLD_02068	2.68e-254	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
ENCJOHLD_02069	1.4e-40	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
ENCJOHLD_02070	6.14e-202	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
ENCJOHLD_02071	1.01e-175	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
ENCJOHLD_02072	7.39e-192	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
ENCJOHLD_02073	1.81e-168	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
ENCJOHLD_02074	3.35e-288	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Nucleoside
ENCJOHLD_02075	3.45e-198	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
ENCJOHLD_02076	2.12e-188	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
ENCJOHLD_02077	1.37e-215	-	-	-	K	-	-	-	LysR substrate binding domain
ENCJOHLD_02078	1.2e-301	-	-	-	EK	-	-	-	Aminotransferase, class I
ENCJOHLD_02079	1.11e-169	fliY	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
ENCJOHLD_02080	2.11e-158	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
ENCJOHLD_02081	3.02e-176	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
ENCJOHLD_02082	1.26e-161	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
ENCJOHLD_02083	8.83e-127	-	-	-	KT	-	-	-	response to antibiotic
ENCJOHLD_02084	8.52e-70	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator
ENCJOHLD_02085	4.95e-132	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
ENCJOHLD_02086	1.53e-198	-	-	-	S	-	-	-	Putative adhesin
ENCJOHLD_02087	0.0	pts26BCA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
ENCJOHLD_02088	0.0	malL	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
ENCJOHLD_02089	2.6e-233	purR2	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
ENCJOHLD_02090	2.51e-261	-	-	-	S	-	-	-	DUF218 domain
ENCJOHLD_02091	2.44e-165	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
ENCJOHLD_02092	2.93e-151	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
ENCJOHLD_02093	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ENCJOHLD_02094	6.26e-101	-	-	-	-	-	-	-	-
ENCJOHLD_02095	6.9e-197	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
ENCJOHLD_02096	3.03e-191	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
ENCJOHLD_02097	1.29e-115	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
ENCJOHLD_02098	0.0	mngB	3.2.1.170	GH38	G	ko:K15524	-	ko00000,ko01000	Glycosyl hydrolases family 38 N-terminal domain
ENCJOHLD_02099	6.69e-155	fptC	-	-	U	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase system, EIIC
ENCJOHLD_02100	2.52e-35	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
ENCJOHLD_02101	5.55e-22	-	-	-	G	ko:K11203	-	ko00000,ko00002,ko02000	PTS system, fructose subfamily
ENCJOHLD_02102	2.11e-104	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
ENCJOHLD_02103	4.08e-101	-	-	-	K	-	-	-	MerR family regulatory protein
ENCJOHLD_02104	2.16e-199	-	-	-	GM	-	-	-	NmrA-like family
ENCJOHLD_02105	0.0	pts28ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
ENCJOHLD_02106	1.25e-164	nth2	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
ENCJOHLD_02108	8.66e-130	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
ENCJOHLD_02109	6.93e-303	-	-	-	S	-	-	-	module of peptide synthetase
ENCJOHLD_02110	3.32e-135	-	-	-	-	-	-	-	-
ENCJOHLD_02111	1.28e-113	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
ENCJOHLD_02112	1.28e-77	-	-	-	S	-	-	-	Enterocin A Immunity
ENCJOHLD_02113	6.46e-49	-	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
ENCJOHLD_02114	4.59e-216	-	3.1.4.17, 3.1.4.53	-	S	ko:K01120,ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
ENCJOHLD_02115	2.8e-135	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
ENCJOHLD_02116	4.14e-84	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
ENCJOHLD_02117	2.88e-164	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
ENCJOHLD_02118	3.84e-186	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
ENCJOHLD_02119	1.03e-34	-	-	-	-	-	-	-	-
ENCJOHLD_02120	1.48e-152	yugP	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
ENCJOHLD_02121	0.0	-	1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31	-	Q	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	ko00000,ko00001,ko01000	Flavin containing amine oxidoreductase
ENCJOHLD_02122	1.04e-212	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Squalene/phytoene synthase
ENCJOHLD_02123	4.68e-235	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
ENCJOHLD_02124	5.81e-251	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
ENCJOHLD_02125	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
ENCJOHLD_02126	2.49e-73	-	-	-	S	-	-	-	Enterocin A Immunity
ENCJOHLD_02127	7.41e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ENCJOHLD_02128	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ENCJOHLD_02129	7.21e-236	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
ENCJOHLD_02130	1.45e-187	ptp2	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
ENCJOHLD_02131	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ENCJOHLD_02133	9.48e-57	-	-	-	-	-	-	-	-
ENCJOHLD_02134	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	C-terminus of AA_permease
ENCJOHLD_02136	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
ENCJOHLD_02137	1.07e-211	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ENCJOHLD_02138	1.54e-228	ydbI	-	-	K	-	-	-	AI-2E family transporter
ENCJOHLD_02139	1.01e-277	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
ENCJOHLD_02140	1.15e-77	-	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
ENCJOHLD_02141	1.97e-60	qacH	-	-	U	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
ENCJOHLD_02142	2.94e-149	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
ENCJOHLD_02143	7.27e-73	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
ENCJOHLD_02144	1.3e-207	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
ENCJOHLD_02145	1.63e-133	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
ENCJOHLD_02147	2.77e-30	-	-	-	-	-	-	-	-
ENCJOHLD_02149	3.91e-124	tag2	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
ENCJOHLD_02150	1.95e-271	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
ENCJOHLD_02151	1.47e-136	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
ENCJOHLD_02152	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
ENCJOHLD_02153	1.8e-134	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
ENCJOHLD_02154	1.59e-121	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
ENCJOHLD_02155	9.61e-84	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ENCJOHLD_02156	4.26e-109	cvpA	-	-	S	-	-	-	Colicin V production protein
ENCJOHLD_02157	5.61e-216	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
ENCJOHLD_02158	4.41e-316	-	-	-	EGP	-	-	-	Major Facilitator
ENCJOHLD_02160	4.54e-54	-	-	-	-	-	-	-	-
ENCJOHLD_02161	3.93e-99	-	-	-	T	-	-	-	Universal stress protein family
ENCJOHLD_02162	5.73e-316	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
ENCJOHLD_02163	5.54e-210	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
ENCJOHLD_02165	7.62e-97	-	-	-	-	-	-	-	-
ENCJOHLD_02166	2.9e-139	-	-	-	-	-	-	-	-
ENCJOHLD_02167	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
ENCJOHLD_02168	1.15e-281	pbpX	-	-	V	-	-	-	Beta-lactamase
ENCJOHLD_02169	4.75e-267	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
ENCJOHLD_02170	1.01e-199	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
ENCJOHLD_02171	3.98e-169	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
ENCJOHLD_02172	1.43e-277	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
ENCJOHLD_02176	3.58e-126	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
ENCJOHLD_02177	3.06e-58	-	-	-	M	-	-	-	group 2 family protein
ENCJOHLD_02178	7.34e-128	cps2G	-	-	M	-	-	-	Stealth protein CR2, conserved region 2
ENCJOHLD_02179	8.71e-112	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
ENCJOHLD_02180	8.59e-47	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
ENCJOHLD_02181	8.35e-217	-	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
ENCJOHLD_02182	4.12e-115	-	-	-	M	-	-	-	Parallel beta-helix repeats
ENCJOHLD_02183	7.98e-202	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
ENCJOHLD_02184	9.23e-130	-	-	-	L	-	-	-	Integrase
ENCJOHLD_02185	2.36e-170	epsB	-	-	M	-	-	-	biosynthesis protein
ENCJOHLD_02186	7.38e-167	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
ENCJOHLD_02187	1.62e-182	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
ENCJOHLD_02188	5.41e-226	cps2D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
ENCJOHLD_02189	1.39e-158	tuaA	-	-	M	-	-	-	Bacterial sugar transferase
ENCJOHLD_02190	1.1e-255	cps4F	-	-	M	-	-	-	Glycosyl transferases group 1
ENCJOHLD_02191	6.22e-243	cps4G	-	-	M	-	-	-	Glycosyltransferase Family 4
ENCJOHLD_02192	5.37e-214	-	-	-	-	-	-	-	-
ENCJOHLD_02193	4.86e-152	cps4I	-	-	M	-	-	-	Glycosyltransferase like family 2
ENCJOHLD_02194	1.37e-50	-	-	-	M	-	-	-	PFAM Glycosyl transferase family 2
ENCJOHLD_02195	1.47e-97	cps2J	-	-	S	-	-	-	Polysaccharide biosynthesis protein
ENCJOHLD_02196	2.91e-23	cps2K	-	-	L	ko:K07473	-	ko00000,ko02048	bacterial-type proximal promoter sequence-specific DNA binding
ENCJOHLD_02198	2.94e-61	-	-	-	S	-	-	-	Tetratricopeptide repeat
ENCJOHLD_02199	3.21e-109	-	-	-	L	-	-	-	AAA ATPase domain
ENCJOHLD_02200	5.77e-111	-	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	UvrD/REP helicase N-terminal domain
ENCJOHLD_02201	4.54e-22	-	-	-	-	-	-	-	-
ENCJOHLD_02202	2.91e-74	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
ENCJOHLD_02205	1.83e-26	-	-	-	M	-	-	-	domain protein
ENCJOHLD_02206	8.71e-33	-	-	-	M	-	-	-	dTDP-4-dehydrorhamnose reductase activity
ENCJOHLD_02209	1.04e-218	-	-	-	-	-	-	-	-
ENCJOHLD_02210	1.44e-104	-	-	-	-	-	-	-	-
ENCJOHLD_02212	7.76e-17	-	-	-	-	-	-	-	-
ENCJOHLD_02213	4.33e-61	-	-	-	-	-	-	-	-
ENCJOHLD_02216	2.91e-32	-	-	-	S	-	-	-	Barstar (barnase inhibitor)
ENCJOHLD_02218	5.05e-70	-	-	-	S	-	-	-	SMI1-KNR4 cell-wall
ENCJOHLD_02220	1.17e-156	CP_1020	-	-	S	-	-	-	zinc ion binding
ENCJOHLD_02221	9.99e-216	cps3A	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
ENCJOHLD_02222	3.28e-229	cps3B	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
ENCJOHLD_02223	6.91e-283	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
ENCJOHLD_02224	4.58e-259	cps3D	-	-	-	-	-	-	-
ENCJOHLD_02225	1.69e-144	cps3E	-	-	-	-	-	-	-
ENCJOHLD_02226	4.03e-207	cps3F	-	-	-	-	-	-	-
ENCJOHLD_02227	3.9e-251	cps3H	-	-	-	-	-	-	-
ENCJOHLD_02228	1.14e-256	cps3I	-	-	G	-	-	-	Acyltransferase family
ENCJOHLD_02229	3.43e-189	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
ENCJOHLD_02230	6.86e-175	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
ENCJOHLD_02231	0.0	-	-	-	M	-	-	-	domain protein
ENCJOHLD_02232	5.36e-97	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
ENCJOHLD_02233	0.0	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
ENCJOHLD_02234	1.38e-155	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
ENCJOHLD_02235	1.06e-68	-	-	-	-	-	-	-	-
ENCJOHLD_02236	1.04e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
ENCJOHLD_02237	1.95e-41	-	-	-	-	-	-	-	-
ENCJOHLD_02238	1.64e-35	-	-	-	-	-	-	-	-
ENCJOHLD_02239	4.14e-132	-	-	-	K	-	-	-	DNA-templated transcription, initiation
ENCJOHLD_02240	1.9e-168	-	-	-	-	-	-	-	-
ENCJOHLD_02241	1.01e-181	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
ENCJOHLD_02242	6.62e-138	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
ENCJOHLD_02243	4.09e-172	lytE	-	-	M	-	-	-	NlpC/P60 family
ENCJOHLD_02244	8.01e-64	-	-	-	K	-	-	-	sequence-specific DNA binding
ENCJOHLD_02245	7.17e-39	-	-	-	S	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
ENCJOHLD_02246	1.67e-166	pbpX	-	-	V	-	-	-	Beta-lactamase
ENCJOHLD_02247	7.3e-216	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
ENCJOHLD_02248	1.13e-257	yueF	-	-	S	-	-	-	AI-2E family transporter
ENCJOHLD_02249	2.46e-93	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
ENCJOHLD_02250	7.89e-290	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
ENCJOHLD_02251	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
ENCJOHLD_02252	3.36e-216	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
ENCJOHLD_02253	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
ENCJOHLD_02254	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ENCJOHLD_02255	0.0	-	-	-	-	-	-	-	-
ENCJOHLD_02256	1.49e-252	-	-	-	M	-	-	-	MucBP domain
ENCJOHLD_02257	3.89e-208	lysR5	-	-	K	-	-	-	LysR substrate binding domain
ENCJOHLD_02258	1.01e-172	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
ENCJOHLD_02259	3.85e-76	ywjH	-	-	S	-	-	-	Protein of unknown function (DUF1634)
ENCJOHLD_02260	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
ENCJOHLD_02261	3.44e-210	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ENCJOHLD_02262	3.59e-241	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ENCJOHLD_02263	4.86e-258	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
ENCJOHLD_02264	5.67e-231	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
ENCJOHLD_02265	3.4e-85	-	-	-	K	-	-	-	Winged helix DNA-binding domain
ENCJOHLD_02266	2.5e-132	-	-	-	L	-	-	-	Integrase
ENCJOHLD_02267	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
ENCJOHLD_02268	5.6e-41	-	-	-	-	-	-	-	-
ENCJOHLD_02269	1.24e-52	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
ENCJOHLD_02270	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ENCJOHLD_02271	6.12e-72	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
ENCJOHLD_02272	5.72e-99	-	-	-	K	-	-	-	LytTr DNA-binding domain
ENCJOHLD_02273	9.72e-146	-	-	-	S	-	-	-	membrane
ENCJOHLD_02274	1.09e-105	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
ENCJOHLD_02275	7.5e-146	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
ENCJOHLD_02276	6.11e-249	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ENCJOHLD_02277	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
ENCJOHLD_02278	6.88e-257	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ENCJOHLD_02279	1.09e-83	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
ENCJOHLD_02280	1.72e-120	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
ENCJOHLD_02281	4.46e-179	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ENCJOHLD_02282	5.58e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
ENCJOHLD_02283	1.4e-208	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
ENCJOHLD_02284	1.21e-129	-	-	-	S	-	-	-	SdpI/YhfL protein family
ENCJOHLD_02285	2.36e-289	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
ENCJOHLD_02286	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
ENCJOHLD_02287	1.93e-218	ubiA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
ENCJOHLD_02288	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
ENCJOHLD_02289	1.38e-155	csrR	-	-	K	-	-	-	response regulator
ENCJOHLD_02290	3.12e-311	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
ENCJOHLD_02291	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ENCJOHLD_02292	8.93e-223	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ENCJOHLD_02293	1.3e-125	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
ENCJOHLD_02294	3.66e-127	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
ENCJOHLD_02295	3.55e-279	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
ENCJOHLD_02296	6.65e-180	yqeM	-	-	Q	-	-	-	Methyltransferase
ENCJOHLD_02297	1.06e-76	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
ENCJOHLD_02298	1.71e-149	yqeK	-	-	H	-	-	-	Hydrolase, HD family
ENCJOHLD_02299	4.19e-153	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ENCJOHLD_02300	2.19e-67	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
ENCJOHLD_02301	3.81e-276	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
ENCJOHLD_02302	5.7e-127	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
ENCJOHLD_02303	4.76e-110	-	-	-	-	-	-	-	-
ENCJOHLD_02304	9.51e-317	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
ENCJOHLD_02305	2.39e-175	racD	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
ENCJOHLD_02306	1.64e-83	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
ENCJOHLD_02307	7.09e-252	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
ENCJOHLD_02308	8.2e-306	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
ENCJOHLD_02309	2.76e-74	-	-	-	-	-	-	-	-
ENCJOHLD_02310	6.88e-73	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ENCJOHLD_02311	6.92e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
ENCJOHLD_02312	2.37e-109	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ENCJOHLD_02313	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ENCJOHLD_02314	6.05e-221	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
ENCJOHLD_02315	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
ENCJOHLD_02316	1.58e-117	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ENCJOHLD_02317	3.88e-133	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ENCJOHLD_02318	3.19e-202	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
ENCJOHLD_02319	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ENCJOHLD_02320	8.51e-155	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
ENCJOHLD_02321	1.04e-141	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
ENCJOHLD_02322	4.07e-60	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
ENCJOHLD_02323	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
ENCJOHLD_02324	2.71e-108	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
ENCJOHLD_02325	1.83e-298	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ENCJOHLD_02326	8.63e-310	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
ENCJOHLD_02327	1.1e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
ENCJOHLD_02328	2.87e-47	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
ENCJOHLD_02329	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
ENCJOHLD_02330	3.04e-29	-	-	-	S	-	-	-	Virus attachment protein p12 family
ENCJOHLD_02331	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
ENCJOHLD_02332	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
ENCJOHLD_02333	1.69e-144	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
ENCJOHLD_02334	1.7e-70	ytzB	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
ENCJOHLD_02335	4.7e-156	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
ENCJOHLD_02336	7.24e-197	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
ENCJOHLD_02337	8.17e-285	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
ENCJOHLD_02338	1.1e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
ENCJOHLD_02339	3.6e-106	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
ENCJOHLD_02340	7.9e-72	-	-	-	-	-	-	-	-
ENCJOHLD_02341	1.09e-196	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
ENCJOHLD_02342	5.76e-135	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
ENCJOHLD_02343	2.82e-138	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
ENCJOHLD_02344	3.36e-248	-	-	-	S	-	-	-	Fn3-like domain
ENCJOHLD_02345	4.75e-80	-	-	-	-	-	-	-	-
ENCJOHLD_02346	0.0	-	-	-	-	-	-	-	-
ENCJOHLD_02347	5.19e-309	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
ENCJOHLD_02348	4.89e-146	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
ENCJOHLD_02349	2.71e-150	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
ENCJOHLD_02350	3.39e-138	-	-	-	-	-	-	-	-
ENCJOHLD_02351	5.21e-137	-	-	-	S	ko:K09962	-	ko00000	Nucleotidyltransferase
ENCJOHLD_02352	1.23e-106	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
ENCJOHLD_02353	2.08e-284	ribA	3.5.4.25, 4.1.99.12	-	H	ko:K02858,ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
ENCJOHLD_02354	8.71e-111	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
ENCJOHLD_02355	4.26e-218	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ENCJOHLD_02356	0.0	-	-	-	S	-	-	-	membrane
ENCJOHLD_02357	2.24e-87	-	-	-	S	-	-	-	NUDIX domain
ENCJOHLD_02358	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ENCJOHLD_02359	3.85e-234	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
ENCJOHLD_02360	0.0	-	-	-	L	-	-	-	MutS domain V
ENCJOHLD_02361	0.0	-	-	-	L	-	-	-	ATPase domain of DNA mismatch repair MUTS family
ENCJOHLD_02362	4.09e-253	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
ENCJOHLD_02363	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
ENCJOHLD_02364	1.81e-64	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
ENCJOHLD_02365	6.28e-69	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
ENCJOHLD_02366	1.41e-58	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
ENCJOHLD_02367	8.65e-126	fusA1	-	-	J	-	-	-	elongation factor G
ENCJOHLD_02368	1.34e-151	azoR	-	-	C	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ENCJOHLD_02369	1.67e-220	-	-	-	K	-	-	-	WYL domain
ENCJOHLD_02370	3.06e-165	-	-	-	F	-	-	-	glutamine amidotransferase
ENCJOHLD_02371	1.65e-106	-	-	-	S	-	-	-	ASCH
ENCJOHLD_02372	0.0	hpaH	1.14.14.8, 1.14.14.9	-	Q	ko:K00483,ko:K16901	ko00350,ko00380,ko01120,ko01220,map00350,map00380,map01120,map01220	ko00000,ko00001,ko01000	4-hydroxyphenylacetate
ENCJOHLD_02373	3.97e-174	ptp1	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
ENCJOHLD_02374	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
ENCJOHLD_02375	1.54e-248	pva1	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
ENCJOHLD_02376	3.83e-155	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
ENCJOHLD_02377	0.0	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
ENCJOHLD_02378	5.07e-157	ydgI	-	-	C	-	-	-	Nitroreductase family
ENCJOHLD_02379	5.74e-204	adc	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
ENCJOHLD_02380	4.06e-211	-	-	-	S	-	-	-	KR domain
ENCJOHLD_02381	4.48e-98	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ENCJOHLD_02382	2.49e-95	-	-	-	C	-	-	-	FMN binding
ENCJOHLD_02383	1.46e-204	-	-	-	K	-	-	-	LysR family
ENCJOHLD_02384	0.0	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
ENCJOHLD_02385	0.0	-	-	-	C	-	-	-	FMN_bind
ENCJOHLD_02386	1.51e-148	-	-	-	S	-	-	-	Elongation factor G-binding protein, N-terminal
ENCJOHLD_02387	2.02e-85	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
ENCJOHLD_02388	2.24e-155	pnb	-	-	C	-	-	-	nitroreductase
ENCJOHLD_02389	3.46e-156	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
ENCJOHLD_02390	0.0	-	-	-	C	-	-	-	Belongs to the aldehyde dehydrogenase family
ENCJOHLD_02391	3.46e-124	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
ENCJOHLD_02392	1.74e-106	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ENCJOHLD_02393	1.5e-253	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
ENCJOHLD_02394	1.71e-200	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
ENCJOHLD_02395	3.54e-195	yycI	-	-	S	-	-	-	YycH protein
ENCJOHLD_02396	1.02e-312	yycH	-	-	S	-	-	-	YycH protein
ENCJOHLD_02397	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
ENCJOHLD_02398	2.22e-169	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
ENCJOHLD_02400	1.28e-53	-	-	-	-	-	-	-	-
ENCJOHLD_02401	2.54e-42	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
ENCJOHLD_02402	4.43e-74	-	-	-	-	-	-	-	-
ENCJOHLD_02403	2.79e-54	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
ENCJOHLD_02404	8e-268	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
ENCJOHLD_02405	2.6e-257	-	-	-	S	-	-	-	Phage portal protein
ENCJOHLD_02406	0.000703	-	-	-	-	-	-	-	-
ENCJOHLD_02407	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
ENCJOHLD_02408	2.22e-108	-	-	-	L	-	-	-	overlaps another CDS with the same product name
ENCJOHLD_02409	1.89e-91	-	-	-	L	ko:K07451	-	ko00000,ko01000,ko02048	Phage-associated protein
ENCJOHLD_02410	3.11e-64	-	-	-	S	-	-	-	Head-tail joining protein
ENCJOHLD_02412	2.14e-83	-	-	-	-	-	-	-	-
ENCJOHLD_02413	0.0	-	-	-	S	-	-	-	Virulence-associated protein E
ENCJOHLD_02414	5.42e-165	-	-	-	L	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
ENCJOHLD_02415	2.75e-33	-	-	-	-	-	-	-	-
ENCJOHLD_02416	6.6e-12	-	-	-	-	-	-	-	-
ENCJOHLD_02418	6.7e-09	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
ENCJOHLD_02419	1.72e-291	sip	-	-	L	-	-	-	Belongs to the 'phage' integrase family
ENCJOHLD_02420	2.54e-50	-	-	-	-	-	-	-	-
ENCJOHLD_02421	4.37e-43	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein domain
ENCJOHLD_02422	2.64e-103	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase
ENCJOHLD_02423	0.0	trePP	2.4.1.216, 2.4.1.8	GH65	G	ko:K00691,ko:K03731	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65 central catalytic domain
ENCJOHLD_02424	1.1e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
ENCJOHLD_02425	8.38e-184	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
ENCJOHLD_02427	0.0	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
ENCJOHLD_02428	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
ENCJOHLD_02429	0.0	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
ENCJOHLD_02430	3.49e-269	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
ENCJOHLD_02431	6.65e-282	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ENCJOHLD_02432	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ENCJOHLD_02434	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
ENCJOHLD_02436	3.25e-292	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ENCJOHLD_02437	9e-184	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ENCJOHLD_02438	4.96e-289	yttB	-	-	EGP	-	-	-	Major Facilitator
ENCJOHLD_02439	8.77e-317	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
ENCJOHLD_02440	3.44e-95	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
ENCJOHLD_02441	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
ENCJOHLD_02442	2.69e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ENCJOHLD_02443	1.68e-108	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
ENCJOHLD_02444	5.95e-65	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
ENCJOHLD_02445	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ENCJOHLD_02446	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ENCJOHLD_02447	7.24e-263	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ENCJOHLD_02448	3.82e-51	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
ENCJOHLD_02449	8.19e-267	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
ENCJOHLD_02450	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ENCJOHLD_02451	3.74e-75	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
ENCJOHLD_02452	1.55e-158	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
ENCJOHLD_02453	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
ENCJOHLD_02454	2.26e-306	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
ENCJOHLD_02455	2.37e-173	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
ENCJOHLD_02456	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ENCJOHLD_02457	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
ENCJOHLD_02458	1.31e-143	-	-	-	S	-	-	-	Cell surface protein
ENCJOHLD_02459	2.23e-211	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
ENCJOHLD_02461	0.0	-	-	-	-	-	-	-	-
ENCJOHLD_02462	7.66e-292	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ENCJOHLD_02463	1.75e-275	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
ENCJOHLD_02464	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
ENCJOHLD_02465	5.28e-105	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
ENCJOHLD_02466	2.15e-137	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ENCJOHLD_02467	4.02e-145	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
ENCJOHLD_02468	2.82e-105	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
ENCJOHLD_02469	1.51e-140	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
ENCJOHLD_02470	4.54e-59	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
ENCJOHLD_02471	2.28e-287	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
ENCJOHLD_02472	3.43e-55	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
ENCJOHLD_02473	5.82e-139	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose fructose sorbose family IID component
ENCJOHLD_02474	4.54e-132	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
ENCJOHLD_02475	3.79e-85	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
ENCJOHLD_02476	1.31e-119	-	-	-	K	-	-	-	Periplasmic binding proteins and sugar binding domain of LacI family
ENCJOHLD_02477	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
ENCJOHLD_02478	7.27e-303	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
ENCJOHLD_02479	1.34e-52	-	-	-	-	-	-	-	-
ENCJOHLD_02480	2.37e-107	uspA	-	-	T	-	-	-	universal stress protein
ENCJOHLD_02481	1.91e-259	bla2	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
ENCJOHLD_02482	4.7e-207	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
ENCJOHLD_02483	0.0	glpQ3	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
ENCJOHLD_02484	6.54e-273	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
ENCJOHLD_02485	7.55e-242	-	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
ENCJOHLD_02486	1.88e-226	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
ENCJOHLD_02487	3.34e-215	hicD3	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
ENCJOHLD_02488	1.23e-190	metQ	-	-	M	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
ENCJOHLD_02489	2.1e-151	metI	-	-	U	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
ENCJOHLD_02490	2.24e-239	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ENCJOHLD_02491	3.2e-64	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
ENCJOHLD_02492	2.15e-280	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
ENCJOHLD_02493	2.54e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
ENCJOHLD_02494	1.52e-57	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
ENCJOHLD_02495	1.44e-230	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
ENCJOHLD_02496	1.68e-132	-	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
ENCJOHLD_02497	2.94e-315	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ENCJOHLD_02498	5.95e-74	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
ENCJOHLD_02499	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ENCJOHLD_02500	9.14e-213	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ENCJOHLD_02501	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ENCJOHLD_02502	2.03e-118	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ENCJOHLD_02503	5.41e-77	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ENCJOHLD_02504	1.81e-37	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ENCJOHLD_02505	4.82e-165	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
ENCJOHLD_02506	2.49e-294	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
ENCJOHLD_02507	7.81e-148	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ENCJOHLD_02508	3.04e-297	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ENCJOHLD_02509	4.39e-244	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
ENCJOHLD_02510	5.96e-205	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
ENCJOHLD_02511	1.88e-251	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ENCJOHLD_02512	1.54e-141	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
ENCJOHLD_02513	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
ENCJOHLD_02514	1.83e-175	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
ENCJOHLD_02515	4.95e-250	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
ENCJOHLD_02516	1.12e-246	ampC	-	-	V	-	-	-	Beta-lactamase
ENCJOHLD_02517	8.57e-41	-	-	-	-	-	-	-	-
ENCJOHLD_02518	1.9e-260	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
ENCJOHLD_02519	1.33e-77	-	-	-	-	-	-	-	-
ENCJOHLD_02520	5.37e-182	-	-	-	-	-	-	-	-
ENCJOHLD_02521	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
ENCJOHLD_02522	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
ENCJOHLD_02523	1.81e-85	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
ENCJOHLD_02524	2.96e-182	icaB	-	-	G	-	-	-	Polysaccharide deacetylase
ENCJOHLD_02527	2.82e-80	-	-	-	K	-	-	-	IrrE N-terminal-like domain
ENCJOHLD_02529	1.82e-54	-	-	-	S	-	-	-	Bacteriophage holin
ENCJOHLD_02530	4.55e-64	-	-	-	-	-	-	-	-
ENCJOHLD_02531	2.62e-263	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
ENCJOHLD_02533	8.44e-91	-	-	-	S	-	-	-	Protein of unknown function (DUF1617)
ENCJOHLD_02534	0.0	-	-	-	LM	-	-	-	DNA recombination
ENCJOHLD_02535	7.67e-80	-	-	-	-	-	-	-	-
ENCJOHLD_02536	0.0	-	-	-	D	-	-	-	domain protein
ENCJOHLD_02537	1.42e-83	-	-	-	-	-	-	-	-
ENCJOHLD_02538	7.42e-102	-	-	-	S	-	-	-	Phage tail tube protein, TTP
ENCJOHLD_02539	2.26e-59	-	-	-	-	-	-	-	-
ENCJOHLD_02540	9.24e-116	-	-	-	-	-	-	-	-
ENCJOHLD_02541	1.55e-67	-	-	-	-	-	-	-	-
ENCJOHLD_02542	2.9e-68	-	-	-	-	-	-	-	-
ENCJOHLD_02544	2.08e-222	-	-	-	S	-	-	-	Phage major capsid protein E
ENCJOHLD_02545	5.72e-64	-	-	-	-	-	-	-	-
ENCJOHLD_02548	3.05e-41	-	-	-	-	-	-	-	-
ENCJOHLD_02549	0.0	-	-	-	S	-	-	-	Phage Mu protein F like protein
ENCJOHLD_02550	4.98e-51	-	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
ENCJOHLD_02551	0.0	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
ENCJOHLD_02552	3.6e-305	-	-	-	S	-	-	-	Terminase-like family
ENCJOHLD_02553	3.4e-82	-	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
ENCJOHLD_02554	3.99e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF2829)
ENCJOHLD_02558	3.86e-107	-	-	-	S	-	-	-	Phage transcriptional regulator, ArpU family
ENCJOHLD_02559	9.86e-08	-	-	-	-	-	-	-	-
ENCJOHLD_02560	4.69e-86	-	-	-	L	-	-	-	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
ENCJOHLD_02561	2.6e-80	-	-	-	-	-	-	-	-
ENCJOHLD_02562	1.81e-82	-	-	-	K	ko:K07741	-	ko00000	AntA/AntB antirepressor
ENCJOHLD_02565	6.09e-101	-	-	-	-	-	-	-	-
ENCJOHLD_02566	1.56e-70	-	-	-	-	-	-	-	-
ENCJOHLD_02568	2.06e-50	-	-	-	K	-	-	-	Helix-turn-helix
ENCJOHLD_02569	2.67e-80	-	-	-	K	-	-	-	Helix-turn-helix domain
ENCJOHLD_02570	2.73e-97	-	-	-	E	-	-	-	IrrE N-terminal-like domain
ENCJOHLD_02571	1.74e-108	-	-	-	-	-	-	-	-
ENCJOHLD_02573	7.9e-74	-	-	-	-	-	-	-	-
ENCJOHLD_02576	1.12e-252	-	-	-	S	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
ENCJOHLD_02580	3.14e-277	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
ENCJOHLD_02582	1.98e-40	-	-	-	-	-	-	-	-
ENCJOHLD_02584	1.28e-51	-	-	-	-	-	-	-	-
ENCJOHLD_02585	9.28e-58	-	-	-	-	-	-	-	-
ENCJOHLD_02586	5.18e-109	-	-	-	K	-	-	-	MarR family
ENCJOHLD_02587	0.0	-	-	-	D	-	-	-	nuclear chromosome segregation
ENCJOHLD_02588	0.0	inlJ	-	-	M	-	-	-	MucBP domain
ENCJOHLD_02589	6.58e-24	-	-	-	-	-	-	-	-
ENCJOHLD_02590	3.26e-24	-	-	-	-	-	-	-	-
ENCJOHLD_02591	1.56e-22	-	-	-	-	-	-	-	-
ENCJOHLD_02592	1.07e-26	-	-	-	-	-	-	-	-
ENCJOHLD_02593	9.35e-24	-	-	-	-	-	-	-	-
ENCJOHLD_02594	9.35e-24	-	-	-	-	-	-	-	-
ENCJOHLD_02595	9.35e-24	-	-	-	-	-	-	-	-
ENCJOHLD_02596	2.16e-26	-	-	-	-	-	-	-	-
ENCJOHLD_02597	4.63e-24	-	-	-	-	-	-	-	-
ENCJOHLD_02598	0.0	-	3.6.3.44	-	P	ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter transmembrane region
ENCJOHLD_02599	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
ENCJOHLD_02600	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
ENCJOHLD_02601	2.1e-33	-	-	-	-	-	-	-	-
ENCJOHLD_02602	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
ENCJOHLD_02603	2.51e-200	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
ENCJOHLD_02604	5.23e-277	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
ENCJOHLD_02605	0.0	yclK	-	-	T	-	-	-	Histidine kinase
ENCJOHLD_02606	3.41e-172	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
ENCJOHLD_02607	2.12e-308	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
ENCJOHLD_02608	6.12e-51	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
ENCJOHLD_02609	2.55e-218	-	-	-	EG	-	-	-	EamA-like transporter family
ENCJOHLD_02611	6.24e-120	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
ENCJOHLD_02612	1.31e-64	-	-	-	-	-	-	-	-
ENCJOHLD_02613	6.83e-274	yceI	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major Facilitator
ENCJOHLD_02614	8.05e-178	-	-	-	F	-	-	-	NUDIX domain
ENCJOHLD_02615	2.68e-32	-	-	-	-	-	-	-	-
ENCJOHLD_02617	8.16e-207	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
ENCJOHLD_02618	4.27e-223	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	NlpC/P60 family
ENCJOHLD_02619	4.17e-107	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
ENCJOHLD_02620	2.29e-48	-	-	-	-	-	-	-	-
ENCJOHLD_02621	1.11e-45	-	-	-	-	-	-	-	-
ENCJOHLD_02622	4.86e-279	-	-	-	T	-	-	-	diguanylate cyclase
ENCJOHLD_02623	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
ENCJOHLD_02624	9.24e-140	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
ENCJOHLD_02625	5.76e-107	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
ENCJOHLD_02626	9.2e-62	-	-	-	-	-	-	-	-
ENCJOHLD_02627	0.0	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
ENCJOHLD_02628	1.46e-239	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ENCJOHLD_02629	3.45e-209	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
ENCJOHLD_02630	1.01e-293	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
ENCJOHLD_02631	6.08e-312	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
ENCJOHLD_02632	8.88e-213	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
ENCJOHLD_02633	9.31e-225	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
ENCJOHLD_02634	6.03e-196	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
ENCJOHLD_02635	1.38e-180	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
ENCJOHLD_02636	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
ENCJOHLD_02637	3.32e-203	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
ENCJOHLD_02638	1.01e-176	yceF	-	-	P	ko:K05794	-	ko00000	membrane
ENCJOHLD_02639	7.09e-125	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
ENCJOHLD_02640	2.13e-255	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ENCJOHLD_02641	1.07e-68	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
ENCJOHLD_02642	6.12e-78	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ENCJOHLD_02643	1.27e-172	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
ENCJOHLD_02644	6.84e-166	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ENCJOHLD_02645	2.23e-142	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ENCJOHLD_02646	2.46e-139	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
ENCJOHLD_02647	1.57e-298	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ENCJOHLD_02648	1.69e-151	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
ENCJOHLD_02649	8.01e-276	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ENCJOHLD_02650	6.46e-208	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphate phosphatase, HisJ
ENCJOHLD_02651	3.72e-283	ysaA	-	-	V	-	-	-	RDD family
ENCJOHLD_02652	1.03e-212	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
ENCJOHLD_02653	6.7e-74	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
ENCJOHLD_02654	4.73e-118	rmeB	-	-	K	-	-	-	transcriptional regulator, MerR family
ENCJOHLD_02655	1.01e-189	-	-	-	GM	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
ENCJOHLD_02656	4.54e-126	-	-	-	J	-	-	-	glyoxalase III activity
ENCJOHLD_02657	1.69e-255	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ENCJOHLD_02658	2.83e-238	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
ENCJOHLD_02659	1.45e-46	-	-	-	-	-	-	-	-
ENCJOHLD_02660	1.26e-143	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
ENCJOHLD_02661	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
ENCJOHLD_02662	0.0	-	-	-	M	-	-	-	domain protein
ENCJOHLD_02663	3e-98	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
ENCJOHLD_02664	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
ENCJOHLD_02665	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
ENCJOHLD_02666	4.01e-236	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
ENCJOHLD_02667	2.14e-183	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
ENCJOHLD_02670	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
ENCJOHLD_02671	1.5e-194	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
ENCJOHLD_02674	4.58e-230	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
ENCJOHLD_02676	1.08e-104	-	-	-	S	-	-	-	Phage regulatory protein Rha (Phage_pRha)
ENCJOHLD_02677	1.6e-55	-	-	-	-	-	-	-	-
ENCJOHLD_02678	1.15e-05	-	-	-	-	-	-	-	-
ENCJOHLD_02681	2.71e-38	-	-	-	-	-	-	-	-
ENCJOHLD_02682	1.08e-172	-	-	-	L	-	-	-	Primase C terminal 1 (PriCT-1)
ENCJOHLD_02683	0.0	-	-	-	S	-	-	-	Virulence-associated protein E
ENCJOHLD_02684	1.85e-82	-	-	-	-	-	-	-	-
ENCJOHLD_02685	1.25e-93	-	-	-	-	-	-	-	-
ENCJOHLD_02687	1.57e-62	-	-	-	-	-	-	-	-
ENCJOHLD_02688	1.96e-224	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
ENCJOHLD_02689	0.0	ybeC	-	-	E	-	-	-	amino acid
ENCJOHLD_02690	2.01e-132	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
ENCJOHLD_02691	8.34e-60	-	-	-	L	ko:K07482	-	ko00000	Integrase core domain
ENCJOHLD_02694	9.02e-66	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
ENCJOHLD_02695	1.38e-71	-	-	-	S	-	-	-	Cupin domain
ENCJOHLD_02696	1.31e-213	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
ENCJOHLD_02697	1.2e-242	ysdE	-	-	P	-	-	-	Citrate transporter
ENCJOHLD_02698	1.06e-195	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
ENCJOHLD_02699	5.35e-175	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ENCJOHLD_02700	2.92e-280	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ENCJOHLD_02701	5.41e-160	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
ENCJOHLD_02702	3.99e-177	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
ENCJOHLD_02703	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ENCJOHLD_02704	5.27e-197	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
ENCJOHLD_02705	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
ENCJOHLD_02706	6.3e-95	-	-	-	-	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	-
ENCJOHLD_02707	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
ENCJOHLD_02708	6.25e-106	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
ENCJOHLD_02709	1.71e-302	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
ENCJOHLD_02710	9.81e-201	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
ENCJOHLD_02712	1e-200	-	-	-	G	-	-	-	Peptidase_C39 like family
ENCJOHLD_02713	6.46e-218	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
ENCJOHLD_02714	4.51e-172	manM	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
ENCJOHLD_02715	1.87e-219	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
ENCJOHLD_02716	9.05e-85	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
ENCJOHLD_02717	0.0	levR	-	-	K	-	-	-	Sigma-54 interaction domain
ENCJOHLD_02718	7.19e-94	levD	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11194	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
ENCJOHLD_02719	1.83e-112	manX	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
ENCJOHLD_02720	3.15e-229	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ENCJOHLD_02721	9.24e-85	accB1	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin-requiring enzyme
ENCJOHLD_02722	4.82e-315	accC1	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase C-terminal domain
ENCJOHLD_02723	6.33e-185	accD1	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ENCJOHLD_02724	1.23e-177	accA1	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
ENCJOHLD_02725	2.29e-234	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
ENCJOHLD_02726	7.53e-215	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
ENCJOHLD_02727	6.04e-227	-	-	-	EG	-	-	-	EamA-like transporter family
ENCJOHLD_02728	1.11e-164	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ENCJOHLD_02729	1.12e-147	zmp2	-	-	O	-	-	-	Zinc-dependent metalloprotease
ENCJOHLD_02730	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
ENCJOHLD_02731	1.62e-158	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ENCJOHLD_02732	5.96e-69	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
ENCJOHLD_02733	9.43e-127	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
ENCJOHLD_02734	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ENCJOHLD_02735	4.91e-265	yacL	-	-	S	-	-	-	domain protein
ENCJOHLD_02736	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ENCJOHLD_02737	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
ENCJOHLD_02738	1.35e-92	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
ENCJOHLD_02739	1.49e-177	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ENCJOHLD_02740	1.75e-126	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
ENCJOHLD_02741	1.12e-130	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Sigma-70 region 2
ENCJOHLD_02742	4.55e-31	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
ENCJOHLD_02743	1e-39	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
ENCJOHLD_02744	1.89e-128	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
ENCJOHLD_02745	2.81e-202	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
ENCJOHLD_02746	9.76e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ENCJOHLD_02747	2.69e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
ENCJOHLD_02748	3.72e-105	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ENCJOHLD_02749	2.76e-74	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
ENCJOHLD_02751	2.95e-282	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
ENCJOHLD_02752	6.19e-15	-	-	-	-	-	-	-	-
ENCJOHLD_02753	6.35e-16	-	-	-	-	-	-	-	-
ENCJOHLD_02760	1.32e-06	-	-	-	K	ko:K07729	-	ko00000,ko03000	DNA-binding helix-turn-helix protein
ENCJOHLD_02768	3.66e-127	-	-	-	-	-	-	-	-
ENCJOHLD_02772	4.5e-299	gshF	6.3.2.2	-	H	ko:K01919,ko:K16786,ko:K16787	ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the glutamate--cysteine ligase type 1 family
ENCJOHLD_02773	3.56e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ENCJOHLD_02774	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
ENCJOHLD_02775	9.36e-317	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
ENCJOHLD_02776	1.15e-150	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
ENCJOHLD_02777	1.74e-211	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
ENCJOHLD_02778	3.76e-184	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
ENCJOHLD_02779	9.47e-115	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
ENCJOHLD_02780	5.41e-150	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
ENCJOHLD_02781	1.23e-187	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
ENCJOHLD_02782	1.89e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
ENCJOHLD_02783	3.17e-149	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
ENCJOHLD_02784	2.61e-199	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
ENCJOHLD_02785	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
ENCJOHLD_02786	8.72e-297	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
ENCJOHLD_02787	0.0	ymfH	-	-	S	-	-	-	Peptidase M16
ENCJOHLD_02788	5.74e-172	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
ENCJOHLD_02789	1.92e-127	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ENCJOHLD_02790	2.21e-294	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
ENCJOHLD_02791	2.43e-264	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ENCJOHLD_02792	6.57e-291	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
ENCJOHLD_02793	6.18e-197	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	YmdB-like protein
ENCJOHLD_02794	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ENCJOHLD_02795	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ENCJOHLD_02796	1.35e-93	-	-	-	-	-	-	-	-
ENCJOHLD_02797	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
ENCJOHLD_02798	2.07e-118	-	-	-	-	-	-	-	-
ENCJOHLD_02799	2.33e-137	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
ENCJOHLD_02800	2.62e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
ENCJOHLD_02801	5.87e-256	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ENCJOHLD_02802	9.91e-289	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
ENCJOHLD_02803	1.03e-60	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
ENCJOHLD_02804	2.48e-276	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ENCJOHLD_02805	8.32e-227	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
ENCJOHLD_02806	1.86e-316	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
ENCJOHLD_02807	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ENCJOHLD_02808	5e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
ENCJOHLD_02809	5.39e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ENCJOHLD_02810	1.31e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
ENCJOHLD_02811	1.06e-49	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
ENCJOHLD_02812	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
ENCJOHLD_02813	3e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
ENCJOHLD_02814	1.45e-161	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
ENCJOHLD_02815	8.74e-195	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
ENCJOHLD_02816	8.49e-144	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ENCJOHLD_02817	4.53e-122	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
ENCJOHLD_02818	7.94e-114	ykuL	-	-	S	-	-	-	(CBS) domain
ENCJOHLD_02819	2.29e-112	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
ENCJOHLD_02820	7.85e-288	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
ENCJOHLD_02821	2.31e-202	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
ENCJOHLD_02822	1.88e-75	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
ENCJOHLD_02823	1.6e-96	-	-	-	-	-	-	-	-
ENCJOHLD_02824	1.84e-105	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
ENCJOHLD_02825	1.55e-275	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
ENCJOHLD_02826	5.44e-232	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
ENCJOHLD_02827	7.88e-211	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
ENCJOHLD_02828	2.44e-65	-	-	-	S	ko:K09004	-	ko00000	DsrE/DsrF-like family
ENCJOHLD_02829	2.21e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
ENCJOHLD_02830	2.06e-205	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ENCJOHLD_02831	1.27e-224	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
ENCJOHLD_02832	6.2e-242	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
ENCJOHLD_02833	1.97e-72	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
ENCJOHLD_02834	1.75e-107	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
ENCJOHLD_02835	3.03e-27	-	-	-	-	ko:K02671	-	ko00000,ko02035,ko02044	-
ENCJOHLD_02836	6.46e-113	-	-	-	S	-	-	-	Prokaryotic N-terminal methylation motif
ENCJOHLD_02838	1.56e-236	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
ENCJOHLD_02839	1.91e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ENCJOHLD_02840	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
ENCJOHLD_02841	5.77e-151	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
ENCJOHLD_02842	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
ENCJOHLD_02843	1.96e-116	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
ENCJOHLD_02844	7.18e-189	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
ENCJOHLD_02845	4.69e-151	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
ENCJOHLD_02846	7.18e-153	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
ENCJOHLD_02847	5.16e-141	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ENCJOHLD_02848	2e-98	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	general stress protein
ENCJOHLD_02849	1.11e-84	-	-	-	-	-	-	-	-
ENCJOHLD_02850	6.21e-39	-	-	-	-	-	-	-	-
ENCJOHLD_02851	2.43e-240	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
ENCJOHLD_02852	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ENCJOHLD_02853	4.86e-45	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
ENCJOHLD_02854	6.45e-111	-	-	-	-	-	-	-	-
ENCJOHLD_02855	2.29e-131	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
ENCJOHLD_02856	1.21e-268	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
ENCJOHLD_02857	6.35e-230	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
ENCJOHLD_02858	2.36e-285	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
ENCJOHLD_02859	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
ENCJOHLD_02860	1.24e-208	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	L-malate dehydrogenase activity
ENCJOHLD_02861	6.24e-61	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
ENCJOHLD_02862	1.23e-177	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
ENCJOHLD_02863	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
ENCJOHLD_02864	6.34e-257	-	-	-	-	-	-	-	-
ENCJOHLD_02865	9.51e-135	-	-	-	-	-	-	-	-
ENCJOHLD_02866	0.0	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
ENCJOHLD_02867	0.0	-	-	-	-	-	-	-	-
ENCJOHLD_02868	2.51e-261	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
ENCJOHLD_02869	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
ENCJOHLD_02870	1.91e-66	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
ENCJOHLD_02871	6.06e-132	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
ENCJOHLD_02872	2.56e-110	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ENCJOHLD_02873	8.61e-251	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
ENCJOHLD_02874	3.85e-157	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
ENCJOHLD_02875	7.1e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
ENCJOHLD_02876	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
ENCJOHLD_02877	2.07e-240	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
ENCJOHLD_02878	1.18e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
ENCJOHLD_02879	2.9e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ENCJOHLD_02880	6.08e-259	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
ENCJOHLD_02881	1.29e-200	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ENCJOHLD_02882	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ENCJOHLD_02883	5.89e-204	-	-	-	S	-	-	-	Tetratricopeptide repeat
ENCJOHLD_02884	4.38e-286	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ENCJOHLD_02885	6.48e-288	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
ENCJOHLD_02886	7.8e-300	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ENCJOHLD_02887	9.6e-143	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
ENCJOHLD_02888	1.3e-65	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
ENCJOHLD_02889	6.47e-95	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
ENCJOHLD_02890	5.12e-31	-	-	-	-	-	-	-	-
ENCJOHLD_02891	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
ENCJOHLD_02892	3.97e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
ENCJOHLD_02893	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
ENCJOHLD_02894	8.45e-162	epsB	-	-	M	-	-	-	biosynthesis protein
ENCJOHLD_02895	4.97e-157	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
ENCJOHLD_02896	5.54e-189	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
ENCJOHLD_02897	8.71e-231	cps4D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
ENCJOHLD_02898	5.49e-163	tuaA	-	-	M	-	-	-	Bacterial sugar transferase
ENCJOHLD_02899	1.4e-259	cps4F	-	-	M	-	-	-	Glycosyl transferases group 1
ENCJOHLD_02900	3.84e-235	cps4G	-	-	M	-	-	-	Glycosyltransferase Family 4
ENCJOHLD_02901	1.01e-292	-	-	-	-	-	-	-	-
ENCJOHLD_02902	2.39e-228	cps4I	-	-	M	-	-	-	Glycosyltransferase like family 2
ENCJOHLD_02903	0.0	cps4J	-	-	S	-	-	-	MatE
ENCJOHLD_02904	3.28e-68	-	3.1.4.53	-	S	ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
ENCJOHLD_02905	2.4e-219	-	3.1.4.53	-	S	ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
ENCJOHLD_02906	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
ENCJOHLD_02907	1.73e-217	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
ENCJOHLD_02908	3.02e-175	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
ENCJOHLD_02909	1.55e-311	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ENCJOHLD_02910	6.62e-62	-	-	-	-	-	-	-	-
ENCJOHLD_02911	3.4e-227	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
ENCJOHLD_02912	7.09e-180	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
ENCJOHLD_02913	1.84e-67	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
ENCJOHLD_02914	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
ENCJOHLD_02915	1.52e-120	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ENCJOHLD_02916	7.9e-136	-	-	-	K	-	-	-	Helix-turn-helix domain
ENCJOHLD_02917	2.87e-270	-	-	-	EGP	-	-	-	Major facilitator Superfamily
ENCJOHLD_02918	2.84e-75	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
ENCJOHLD_02919	1.14e-180	-	-	-	Q	-	-	-	Methyltransferase
ENCJOHLD_02920	1.75e-43	-	-	-	-	-	-	-	-
ENCJOHLD_02923	8.56e-74	-	-	-	S	-	-	-	Phage integrase family
ENCJOHLD_02924	2.87e-42	-	-	-	L	ko:K07483	-	ko00000	transposase activity
ENCJOHLD_02925	2.14e-53	-	-	-	L	-	-	-	HTH-like domain
ENCJOHLD_02926	5.48e-05	-	-	-	S	-	-	-	Short C-terminal domain
ENCJOHLD_02927	1.66e-22	-	-	-	S	-	-	-	Short C-terminal domain
ENCJOHLD_02928	1.6e-221	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ENCJOHLD_02929	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
ENCJOHLD_02930	1.02e-155	-	-	-	S	-	-	-	repeat protein
ENCJOHLD_02931	2.41e-157	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
ENCJOHLD_02932	0.0	-	-	-	N	-	-	-	domain, Protein
ENCJOHLD_02933	4.08e-247	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
ENCJOHLD_02934	5.92e-153	-	-	-	N	-	-	-	WxL domain surface cell wall-binding
ENCJOHLD_02935	4.64e-150	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
ENCJOHLD_02936	9.64e-307	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
ENCJOHLD_02937	3.19e-285	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
ENCJOHLD_02938	4.94e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
ENCJOHLD_02939	3.69e-278	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
ENCJOHLD_02940	5.85e-158	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ENCJOHLD_02941	7.74e-47	-	-	-	-	-	-	-	-
ENCJOHLD_02942	3.51e-125	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
ENCJOHLD_02943	3.46e-242	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ENCJOHLD_02944	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ENCJOHLD_02945	6.52e-124	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
ENCJOHLD_02946	2.06e-187	ylmH	-	-	S	-	-	-	S4 domain protein
ENCJOHLD_02947	6.45e-49	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
ENCJOHLD_02948	1.56e-93	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
ENCJOHLD_02949	9.39e-295	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ENCJOHLD_02950	1.44e-311	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
ENCJOHLD_02951	2.34e-208	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
ENCJOHLD_02952	5e-253	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ENCJOHLD_02953	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ENCJOHLD_02954	2.81e-231	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ENCJOHLD_02955	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
ENCJOHLD_02956	7.01e-76	ftsL	-	-	D	-	-	-	Cell division protein FtsL
ENCJOHLD_02957	2.58e-226	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
ENCJOHLD_02958	1.35e-100	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
ENCJOHLD_02959	3.22e-82	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
ENCJOHLD_02960	4.99e-224	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
ENCJOHLD_02961	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
ENCJOHLD_02962	4.97e-124	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
ENCJOHLD_02963	1.76e-147	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
ENCJOHLD_02964	8.82e-302	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
ENCJOHLD_02966	4.55e-207	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
ENCJOHLD_02967	4.82e-55	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ENCJOHLD_02968	9.52e-264	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
ENCJOHLD_02969	1.55e-74	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
ENCJOHLD_02970	1.6e-246	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
ENCJOHLD_02971	2.51e-150	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
ENCJOHLD_02972	1.09e-222	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
ENCJOHLD_02973	1.29e-193	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ENCJOHLD_02974	9.08e-157	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
ENCJOHLD_02975	2.24e-148	yjbH	-	-	Q	-	-	-	Thioredoxin
ENCJOHLD_02976	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
ENCJOHLD_02977	7.52e-263	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
ENCJOHLD_02978	7.12e-170	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
ENCJOHLD_02979	5.37e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
ENCJOHLD_02980	2.81e-178	yhfI	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
ENCJOHLD_02981	1.08e-117	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
ENCJOHLD_03002	2.76e-141	sip3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
ENCJOHLD_03004	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
ENCJOHLD_03005	1.67e-79	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
ENCJOHLD_03006	4.02e-203	degV1	-	-	S	-	-	-	DegV family
ENCJOHLD_03007	3.66e-113	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
ENCJOHLD_03008	3.79e-181	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
ENCJOHLD_03009	2.71e-135	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
ENCJOHLD_03010	7.43e-130	padR	-	-	K	-	-	-	Virulence activator alpha C-term
ENCJOHLD_03011	2.51e-103	-	-	-	T	-	-	-	Universal stress protein family
ENCJOHLD_03012	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
ENCJOHLD_03013	4.04e-241	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
ENCJOHLD_03014	3.87e-210	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ENCJOHLD_03015	4.99e-88	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
ENCJOHLD_03016	2.53e-209	rbsU	-	-	U	ko:K06216	-	ko00000,ko02000	ribose uptake protein RbsU
ENCJOHLD_03017	2.21e-185	srlD2	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
ENCJOHLD_03018	0.0	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
ENCJOHLD_03019	3.33e-113	srlM1	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
ENCJOHLD_03020	1.23e-129	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
ENCJOHLD_03021	2.5e-234	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
ENCJOHLD_03022	6.96e-83	pts38A	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
ENCJOHLD_03023	1.91e-201	lrp	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
ENCJOHLD_03024	1.48e-247	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
ENCJOHLD_03025	0.0	yknV	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
ENCJOHLD_03026	0.0	mdlA2	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
ENCJOHLD_03027	2.72e-199	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
ENCJOHLD_03028	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain
ENCJOHLD_03029	1.29e-231	ypdA	-	-	U	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
ENCJOHLD_03030	6.47e-213	lplC	-	-	U	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
ENCJOHLD_03031	0.0	ypcG	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Domain of unknown function (DUF3502)
ENCJOHLD_03032	0.0	dexB	3.2.1.70	-	G	ko:K01215	-	ko00000,ko01000	Alpha amylase, catalytic domain protein
ENCJOHLD_03033	1.71e-139	ypcB	-	-	S	-	-	-	integral membrane protein
ENCJOHLD_03034	0.0	-	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
ENCJOHLD_03035	0.0	-	-	-	K	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
ENCJOHLD_03036	3.76e-212	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
ENCJOHLD_03037	1.09e-275	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
ENCJOHLD_03038	0.0	ypdD	-	-	G	-	-	-	Glycosyl hydrolase family 92
ENCJOHLD_03039	1.54e-247	-	-	-	K	-	-	-	Transcriptional regulator
ENCJOHLD_03040	0.0	-	-	-	S	ko:K09704	-	ko00000	Metal-independent alpha-mannosidase (GH125)
ENCJOHLD_03041	0.0	-	2.3.1.204, 3.2.1.170, 3.2.1.24	GH38	G	ko:K01191,ko:K15524,ko:K16869	ko00511,map00511	ko00000,ko00001,ko01000,ko04131	Glycosyl hydrolases family 38 N-terminal domain
ENCJOHLD_03042	4.02e-205	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
ENCJOHLD_03043	0.0	bgl	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
ENCJOHLD_03044	6.56e-28	-	-	-	-	-	-	-	-
ENCJOHLD_03045	3.95e-92	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
ENCJOHLD_03046	1.28e-35	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
ENCJOHLD_03047	1.09e-122	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
ENCJOHLD_03049	3.38e-230	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
ENCJOHLD_03050	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
ENCJOHLD_03051	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
ENCJOHLD_03052	8.08e-122	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
ENCJOHLD_03053	4.54e-207	mleR2	-	-	K	-	-	-	LysR family transcriptional regulator
ENCJOHLD_03054	6.5e-215	mleR	-	-	K	-	-	-	LysR family
ENCJOHLD_03055	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
ENCJOHLD_03056	2.6e-212	mleP2	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
ENCJOHLD_03057	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
ENCJOHLD_03058	4.37e-128	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
ENCJOHLD_03059	6.07e-33	-	-	-	-	-	-	-	-
ENCJOHLD_03060	0.0	-	-	-	S	ko:K06889	-	ko00000	Alpha beta
ENCJOHLD_03061	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
ENCJOHLD_03062	7.76e-234	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
ENCJOHLD_03063	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
ENCJOHLD_03064	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ENCJOHLD_03065	1.89e-208	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
ENCJOHLD_03066	2.11e-233	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
ENCJOHLD_03067	8.5e-213	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
ENCJOHLD_03068	9.47e-236	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
ENCJOHLD_03069	2.92e-147	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
ENCJOHLD_03070	2.01e-134	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
ENCJOHLD_03071	2.67e-119	yebE	-	-	S	-	-	-	UPF0316 protein
ENCJOHLD_03072	1.39e-279	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ENCJOHLD_03073	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
ENCJOHLD_03074	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ENCJOHLD_03075	9.48e-263	camS	-	-	S	-	-	-	sex pheromone
ENCJOHLD_03076	5.11e-67	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ENCJOHLD_03077	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
ENCJOHLD_03078	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ENCJOHLD_03079	1.59e-242	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
ENCJOHLD_03080	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ENCJOHLD_03081	5.56e-130	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
ENCJOHLD_03082	0.0	yfgQ	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
ENCJOHLD_03083	7.06e-307	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
ENCJOHLD_03084	2.87e-215	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
ENCJOHLD_03085	5.63e-196	gntR	-	-	K	-	-	-	rpiR family
ENCJOHLD_03086	6.64e-187	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
ENCJOHLD_03087	7.34e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
ENCJOHLD_03088	6.22e-43	cspP	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
ENCJOHLD_03089	1.94e-245	mocA	-	-	S	-	-	-	Oxidoreductase
ENCJOHLD_03090	4.68e-315	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
ENCJOHLD_03092	2.61e-205	XK27_10395	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ENCJOHLD_03093	1.06e-138	-	-	-	L	-	-	-	Resolvase, N terminal domain
ENCJOHLD_03094	6.35e-147	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
ENCJOHLD_03095	3.29e-232	-	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleotide reductase, small chain
ENCJOHLD_03096	5.59e-220	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleotide reductase, small chain
ENCJOHLD_03097	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ENCJOHLD_03098	7.07e-106	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
ENCJOHLD_03099	1.98e-06	-	3.3.1.1	-	H	ko:K01251	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	adenosylhomocysteinase activity
ENCJOHLD_03100	4.28e-81	ypgQ	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
ENCJOHLD_03101	5.82e-124	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
ENCJOHLD_03102	8.23e-218	-	-	-	L	ko:K07482	-	ko00000	Transposase and inactivated derivatives, IS30 family
ENCJOHLD_03103	4.36e-148	-	-	-	EGP	-	-	-	Transmembrane secretion effector
ENCJOHLD_03104	2.34e-90	thiF	2.7.7.73	-	H	ko:K03148	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	ThiF family
ENCJOHLD_03106	1.49e-73	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
ENCJOHLD_03107	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
ENCJOHLD_03108	2.64e-126	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
ENCJOHLD_03109	1.04e-243	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
ENCJOHLD_03110	3.68e-87	-	3.1.11.5	-	L	ko:K03581,ko:K07452,ko:K09384	ko03440,map03440	ko00000,ko00001,ko01000,ko02048,ko03400	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ENCJOHLD_03111	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
ENCJOHLD_03112	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
ENCJOHLD_03113	4.86e-104	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
ENCJOHLD_03114	7.12e-256	glmS2	-	-	M	-	-	-	SIS domain
ENCJOHLD_03115	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ENCJOHLD_03116	5.51e-284	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
ENCJOHLD_03117	4.21e-158	-	-	-	S	-	-	-	YjbR
ENCJOHLD_03119	0.0	cadA	-	-	P	-	-	-	P-type ATPase
ENCJOHLD_03120	0.0	-	-	-	U	ko:K03451	-	ko00000	Belongs to the BCCT transporter (TC 2.A.15) family
ENCJOHLD_03121	1.3e-157	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
ENCJOHLD_03122	4.29e-101	-	-	-	-	-	-	-	-
ENCJOHLD_03123	5.09e-51	-	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
ENCJOHLD_03124	3.23e-73	-	-	-	FG	-	-	-	HIT domain
ENCJOHLD_03125	1.66e-40	-	-	-	FG	-	-	-	HIT domain
ENCJOHLD_03126	1.05e-223	ydhF	-	-	S	-	-	-	Aldo keto reductase
ENCJOHLD_03127	8.93e-71	-	-	-	S	-	-	-	Pfam:DUF59
ENCJOHLD_03128	1.12e-206	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ENCJOHLD_03129	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
ENCJOHLD_03130	1.87e-249	-	-	-	V	-	-	-	Beta-lactamase
ENCJOHLD_03131	3.74e-125	-	-	-	V	-	-	-	VanZ like family
ENCJOHLD_03132	9.44e-243	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
ENCJOHLD_03133	4.53e-45	-	-	-	-	-	-	-	-
ENCJOHLD_03134	0.0	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
ENCJOHLD_03135	0.0	-	-	-	L	-	-	-	MobA MobL family protein
ENCJOHLD_03136	1.69e-37	-	-	-	-	-	-	-	-
ENCJOHLD_03137	1.03e-55	-	-	-	-	-	-	-	-
ENCJOHLD_03138	5.24e-73	-	-	-	L	-	-	-	Transposase DDE domain
ENCJOHLD_03139	6.98e-211	-	-	-	P	-	-	-	CorA-like Mg2+ transporter protein
ENCJOHLD_03140	1.79e-63	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
ENCJOHLD_03141	6.99e-109	-	-	-	-	-	-	-	-
ENCJOHLD_03142	2.83e-58	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
ENCJOHLD_03144	6.13e-127	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
ENCJOHLD_03146	1.96e-225	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
ENCJOHLD_03147	1.71e-241	-	-	-	L	-	-	-	PFAM Integrase catalytic region
ENCJOHLD_03148	9.17e-126	gbuC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
ENCJOHLD_03149	1.14e-143	gbuB	-	-	E	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
ENCJOHLD_03150	5.99e-234	gbuA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
ENCJOHLD_03151	7.09e-149	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
ENCJOHLD_03152	3.15e-26	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
ENCJOHLD_03153	9.07e-22	-	-	-	L	ko:K07487	-	ko00000	Transposase
ENCJOHLD_03154	2.12e-27	-	-	-	L	ko:K07487	-	ko00000	Transposase
ENCJOHLD_03156	2.72e-70	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
ENCJOHLD_03158	3.07e-06	-	-	-	D	-	-	-	Mycoplasma protein of unknown function, DUF285
ENCJOHLD_03160	2.15e-17	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
ENCJOHLD_03161	2.28e-22	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
ENCJOHLD_03162	4.32e-16	-	-	-	L	-	-	-	Helix-turn-helix domain
ENCJOHLD_03163	2.03e-12	-	-	-	L	-	-	-	Helix-turn-helix domain
ENCJOHLD_03166	2.76e-28	-	-	-	S	-	-	-	Cell surface protein
ENCJOHLD_03167	1.08e-208	-	-	-	-	-	-	-	-
ENCJOHLD_03169	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
ENCJOHLD_03170	1.56e-46	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
ENCJOHLD_03171	5.8e-291	araT	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
ENCJOHLD_03172	6.56e-292	dacA2	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
ENCJOHLD_03173	8.79e-241	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ENCJOHLD_03174	2.04e-254	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
ENCJOHLD_03175	1.41e-285	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
ENCJOHLD_03176	1.02e-226	-	-	-	K	-	-	-	LysR substrate binding domain
ENCJOHLD_03177	9.9e-144	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
ENCJOHLD_03178	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
ENCJOHLD_03179	4.43e-129	-	-	-	-	-	-	-	-
ENCJOHLD_03180	1.17e-100	-	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside 2-deoxyribosyltransferase
ENCJOHLD_03181	2.68e-71	-	-	-	M	-	-	-	domain protein
ENCJOHLD_03182	7.43e-28	-	-	-	M	-	-	-	domain protein
ENCJOHLD_03183	1.87e-139	-	-	-	L	-	-	-	Integrase
ENCJOHLD_03184	4.17e-55	-	-	-	K	-	-	-	prlF antitoxin for toxin YhaV_toxin
ENCJOHLD_03185	1.03e-77	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
ENCJOHLD_03186	0.0	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
ENCJOHLD_03188	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
ENCJOHLD_03191	7.81e-247	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
ENCJOHLD_03192	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
ENCJOHLD_03193	5.12e-112	-	-	-	-	-	-	-	-
ENCJOHLD_03194	5.47e-167	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
ENCJOHLD_03195	4.76e-181	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
ENCJOHLD_03197	3.33e-27	-	-	-	M	-	-	-	domain protein
ENCJOHLD_03198	4.04e-62	-	-	-	M	-	-	-	domain protein
ENCJOHLD_03199	4.59e-201	-	-	-	L	-	-	-	DnaD domain protein
ENCJOHLD_03200	2.8e-70	-	-	-	S	-	-	-	Bacteriophage Mu Gam like protein
ENCJOHLD_03201	3.13e-99	-	-	-	L	-	-	-	Transposase DDE domain
ENCJOHLD_03202	3.33e-89	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
ENCJOHLD_03203	8.27e-89	-	-	-	L	-	-	-	manually curated
ENCJOHLD_03204	3.88e-20	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
ENCJOHLD_03205	3.51e-27	-	-	-	-	-	-	-	-
ENCJOHLD_03206	3.97e-30	-	-	-	-	-	-	-	-
ENCJOHLD_03207	4.02e-73	-	-	-	L	-	-	-	Initiator Replication protein
ENCJOHLD_03208	4.9e-39	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
ENCJOHLD_03209	4.1e-15	-	-	-	S	-	-	-	Haemolysin XhlA
ENCJOHLD_03211	2.15e-65	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
ENCJOHLD_03213	5.47e-70	-	-	-	L	-	-	-	Transposase
ENCJOHLD_03214	2.24e-33	mob	-	-	D	-	-	-	Plasmid recombination enzyme
ENCJOHLD_03216	3.31e-32	-	-	-	-	-	-	-	-
ENCJOHLD_03217	1.98e-54	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties