ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
HEGIFEPM_00001 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HEGIFEPM_00002 3.74e-75 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HEGIFEPM_00003 1.55e-158 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HEGIFEPM_00004 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HEGIFEPM_00005 2.26e-306 - - - Q - - - Imidazolonepropionase and related amidohydrolases
HEGIFEPM_00006 2.37e-173 jag - - S ko:K06346 - ko00000 R3H domain protein
HEGIFEPM_00007 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HEGIFEPM_00008 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HEGIFEPM_00009 1.31e-143 - - - S - - - Cell surface protein
HEGIFEPM_00010 5.92e-168 - - - S - - - Bacterial protein of unknown function (DUF916)
HEGIFEPM_00012 0.0 - - - - - - - -
HEGIFEPM_00013 1.12e-140 sip3 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HEGIFEPM_00015 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
HEGIFEPM_00016 2.38e-79 - - - K - - - Bacteriophage CI repressor helix-turn-helix domain
HEGIFEPM_00017 4.02e-203 degV1 - - S - - - DegV family
HEGIFEPM_00018 3.66e-113 - - - K - - - Acetyltransferase (GNAT) domain
HEGIFEPM_00019 4.62e-182 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
HEGIFEPM_00020 2.71e-135 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
HEGIFEPM_00021 7.43e-130 padR - - K - - - Virulence activator alpha C-term
HEGIFEPM_00022 2.51e-103 - - - T - - - Universal stress protein family
HEGIFEPM_00023 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
HEGIFEPM_00024 2.78e-247 xylP - - G ko:K03292 - ko00000 MFS/sugar transport protein
HEGIFEPM_00025 0.0 yicI 3.2.1.177 GH31 G ko:K01811 - ko00000,ko01000 Belongs to the glycosyl hydrolase 31 family
HEGIFEPM_00026 1.68e-169 xylR - - GK - - - ROK family
HEGIFEPM_00027 7.2e-315 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
HEGIFEPM_00028 5.01e-258 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Xylulose kinase
HEGIFEPM_00029 4.04e-241 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HEGIFEPM_00030 9.52e-211 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HEGIFEPM_00031 2.03e-87 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HEGIFEPM_00032 2.83e-206 rbsU - - U ko:K06216 - ko00000,ko02000 ribose uptake protein RbsU
HEGIFEPM_00033 1.47e-115 yveB - - I - - - PAP2 superfamily
HEGIFEPM_00034 8.33e-53 licB2 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HEGIFEPM_00035 1.24e-199 - - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEGIFEPM_00036 7.39e-43 - 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
HEGIFEPM_00037 8.65e-148 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
HEGIFEPM_00038 4.31e-208 - - - K - - - helix_turn_helix gluconate operon transcriptional repressor
HEGIFEPM_00039 0.0 yknV - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HEGIFEPM_00040 0.0 mdlA2 - - V ko:K06147 - ko00000,ko02000 ABC transporter
HEGIFEPM_00041 7.25e-152 - - - K - - - helix_turn_helix, arabinose operon control protein
HEGIFEPM_00042 0.0 - 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 Glycosyl hydrolase family 20, catalytic domain
HEGIFEPM_00043 3.69e-231 ypdA - - U ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HEGIFEPM_00044 6.47e-213 lplC - - U ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HEGIFEPM_00045 0.0 ypcG - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Domain of unknown function (DUF3502)
HEGIFEPM_00046 0.0 dexB 3.2.1.70 - G ko:K01215 - ko00000,ko01000 Alpha amylase, catalytic domain protein
HEGIFEPM_00047 1.71e-139 ypcB - - S - - - integral membrane protein
HEGIFEPM_00048 0.0 - 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HEGIFEPM_00049 0.0 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
HEGIFEPM_00050 3.76e-212 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
HEGIFEPM_00051 1.09e-275 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HEGIFEPM_00052 0.0 ypdD - - G - - - Glycosyl hydrolase family 92
HEGIFEPM_00053 2.66e-248 - - - K - - - Transcriptional regulator
HEGIFEPM_00054 0.0 - - - S ko:K09704 - ko00000 Metal-independent alpha-mannosidase (GH125)
HEGIFEPM_00055 0.0 - 2.3.1.204, 3.2.1.170, 3.2.1.24 GH38 G ko:K01191,ko:K15524,ko:K16869 ko00511,map00511 ko00000,ko00001,ko01000,ko04131 Glycosyl hydrolases family 38 N-terminal domain
HEGIFEPM_00056 1.4e-205 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
HEGIFEPM_00057 0.0 bgl 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HEGIFEPM_00058 5.18e-186 srlD 1.1.1.140 - IQ ko:K00068 ko00051,map00051 ko00000,ko00001,ko01000 NAD dependent epimerase/dehydratase family
HEGIFEPM_00059 0.0 srlM - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
HEGIFEPM_00060 4.71e-119 srlM1 - - K - - - Glucitol operon activator protein (GutM)
HEGIFEPM_00061 1.88e-131 srlA - - G ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko02000 PTS system enzyme II sorbitol-specific factor
HEGIFEPM_00062 2.19e-227 srlE 2.7.1.198 - G ko:K02782,ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Sorbitol phosphotransferase enzyme II N-terminus
HEGIFEPM_00063 5.31e-82 pts38A 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
HEGIFEPM_00064 1.69e-148 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
HEGIFEPM_00065 1.44e-228 - - - F ko:K01250 - ko00000,ko01000 Inosine-uridine preferring nucleoside hydrolase
HEGIFEPM_00066 1.6e-220 - - - C - - - Alcohol dehydrogenase GroES-like domain
HEGIFEPM_00067 7.45e-108 - - - S - - - Haem-degrading
HEGIFEPM_00068 1.87e-246 - 1.1.1.18, 1.1.1.361, 1.1.1.369 - S ko:K00010,ko:K18652 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
HEGIFEPM_00069 0.0 iolT - - EGP ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HEGIFEPM_00070 6.56e-252 idhA 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
HEGIFEPM_00071 3.39e-226 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HEGIFEPM_00072 2.4e-258 iolG 1.1.1.18, 1.1.1.369 - C ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HEGIFEPM_00073 1.01e-252 iolG2 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
HEGIFEPM_00074 0.0 - - - EGP - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HEGIFEPM_00075 5.04e-173 - 4.1.2.17 - G ko:K01628 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 Class II Aldolase and Adducin N-terminal domain
HEGIFEPM_00077 0.0 pts36C - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
HEGIFEPM_00078 2.47e-68 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HEGIFEPM_00079 3.71e-105 pts36A 2.7.1.200 - G ko:K02773 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HEGIFEPM_00080 4.28e-179 - - - K - - - DeoR C terminal sensor domain
HEGIFEPM_00081 1.44e-230 rhaR - - K - - - helix_turn_helix, arabinose operon control protein
HEGIFEPM_00082 4.04e-315 iolF - - P ko:K06610 - ko00000,ko02000 Sugar (and other) transporter
HEGIFEPM_00083 0.0 rhaB 2.7.1.5 - F ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HEGIFEPM_00084 4.22e-74 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
HEGIFEPM_00085 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 L-rhamnose isomerase (RhaA)
HEGIFEPM_00086 1.31e-210 rhaD 4.1.2.19 - H ko:K01629 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
HEGIFEPM_00087 1.45e-162 - - - S - - - Membrane
HEGIFEPM_00088 1.65e-93 yueI - - S - - - Protein of unknown function (DUF1694)
HEGIFEPM_00089 0.0 spxB 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
HEGIFEPM_00090 5.03e-95 - - - K - - - Transcriptional regulator
HEGIFEPM_00091 0.0 pox4 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
HEGIFEPM_00092 8.03e-256 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HEGIFEPM_00094 0.0 clpL - - O ko:K04086 - ko00000,ko03110 C-terminal, D2-small domain, of ClpB protein
HEGIFEPM_00095 2.91e-125 - - - KOT ko:K07813 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01002 May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
HEGIFEPM_00096 3.82e-24 - - - - - - - -
HEGIFEPM_00097 7.01e-286 blpH 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
HEGIFEPM_00098 3.67e-174 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
HEGIFEPM_00099 1.32e-101 nrp - - K ko:K16509 - ko00000 ArsC family
HEGIFEPM_00100 0.0 katA 1.11.1.6 - C ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 Belongs to the catalase family
HEGIFEPM_00101 1.96e-21 ytgB - - S - - - Transglycosylase associated protein
HEGIFEPM_00102 1.06e-16 - - - - - - - -
HEGIFEPM_00103 2.1e-116 - - - T - - - ECF transporter, substrate-specific component
HEGIFEPM_00104 2.43e-91 - - - S - - - Pyrimidine dimer DNA glycosylase
HEGIFEPM_00105 5.6e-292 - - - S - - - Pyridine nucleotide-disulphide oxidoreductase
HEGIFEPM_00106 5.39e-153 nanE 5.1.3.9 - G ko:K01788 ko00520,map00520 ko00000,ko00001,ko01000 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HEGIFEPM_00107 7.98e-125 icaA - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyltransferases, probably involved in cell wall biogenesis
HEGIFEPM_00109 1.85e-61 icaB - - G ko:K21478 - ko00000,ko01000 Polysaccharide deacetylase
HEGIFEPM_00110 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
HEGIFEPM_00111 3.05e-161 - - - K ko:K02444 - ko00000,ko03000 DeoR C terminal sensor domain
HEGIFEPM_00112 3.99e-106 - 2.7.1.200, 2.7.1.204 - G ko:K02773,ko:K20112 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HEGIFEPM_00113 6e-60 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HEGIFEPM_00114 8.37e-296 gatC - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
HEGIFEPM_00115 5.26e-247 - 1.1.1.14 - C ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Zinc-binding dehydrogenase
HEGIFEPM_00116 4.53e-146 gph3 - - S - - - Haloacid dehalogenase-like hydrolase
HEGIFEPM_00117 6.28e-56 - - - G ko:K03483 - ko00000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HEGIFEPM_00118 0.0 - - - G ko:K03483 - ko00000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HEGIFEPM_00119 1.58e-101 - 2.7.1.194 - G ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HEGIFEPM_00120 7.29e-61 ulaB 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase system galactitol-specific IIB component
HEGIFEPM_00121 1.56e-09 ulaA - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
HEGIFEPM_00122 8.12e-261 ulaA - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
HEGIFEPM_00123 7.45e-150 tal 2.2.1.2 - F ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HEGIFEPM_00124 0.0 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HEGIFEPM_00125 6.33e-187 yxeH - - S - - - hydrolase
HEGIFEPM_00126 8.11e-237 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HEGIFEPM_00128 0.0 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
HEGIFEPM_00129 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
HEGIFEPM_00130 2.66e-222 cytR - - K ko:K02529,ko:K03604 - ko00000,ko03000 Transcriptional regulator, LacI family
HEGIFEPM_00131 0.0 treP 2.4.1.64 GH65 G ko:K05342 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
HEGIFEPM_00132 1.3e-203 bglG5 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
HEGIFEPM_00133 0.0 pts33BCA - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HEGIFEPM_00134 1.49e-11 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HEGIFEPM_00135 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HEGIFEPM_00136 0.0 pbg9 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HEGIFEPM_00137 5.63e-253 - 4.2.1.126 - S ko:K07106,ko:K09963 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Bacterial protein of unknown function (DUF871)
HEGIFEPM_00138 8.71e-202 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HEGIFEPM_00139 0.0 pts32BC 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HEGIFEPM_00140 1.96e-191 yleF - - K - - - Helix-turn-helix domain, rpiR family
HEGIFEPM_00141 5.18e-104 - 2.7.1.208 - G ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HEGIFEPM_00142 2.02e-97 - - - G ko:K11201 - ko00000,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HEGIFEPM_00143 0.0 pts31BC - - G ko:K11202,ko:K11203 - ko00000,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HEGIFEPM_00144 4.72e-286 malY 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase class I and II
HEGIFEPM_00145 0.0 - - - G - - - Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HEGIFEPM_00146 3.72e-200 bglG4 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
HEGIFEPM_00147 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HEGIFEPM_00148 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HEGIFEPM_00149 7.57e-268 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
HEGIFEPM_00150 3.71e-206 - - - G - - - BadF/BadG/BcrA/BcrD ATPase family
HEGIFEPM_00151 5.01e-210 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HEGIFEPM_00152 8.41e-316 pts29C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEGIFEPM_00153 5.44e-174 - - - K - - - UTRA domain
HEGIFEPM_00154 2.63e-200 estA - - S - - - Putative esterase
HEGIFEPM_00155 2.09e-83 - - - - - - - -
HEGIFEPM_00156 1.12e-262 - - - EGP - - - Major Facilitator Superfamily
HEGIFEPM_00157 1.73e-215 - - - K - - - Transcriptional regulator, LysR family
HEGIFEPM_00158 5.56e-212 - - - G - - - Xylose isomerase-like TIM barrel
HEGIFEPM_00159 1.64e-202 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
HEGIFEPM_00160 3.31e-205 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HEGIFEPM_00161 2.83e-206 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HEGIFEPM_00162 1.33e-61 - - - EGP - - - Major Facilitator Superfamily
HEGIFEPM_00163 3.98e-207 - - - EGP - - - Major Facilitator Superfamily
HEGIFEPM_00164 4.62e-224 - - - K - - - Transcriptional regulator, LysR family
HEGIFEPM_00165 7.89e-213 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HEGIFEPM_00166 3.65e-172 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HEGIFEPM_00167 1.23e-228 apbE3 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HEGIFEPM_00168 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
HEGIFEPM_00169 2.02e-85 - - - S - - - pyridoxamine 5-phosphate
HEGIFEPM_00170 5.16e-248 tas3 - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
HEGIFEPM_00171 3.69e-232 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HEGIFEPM_00172 1.67e-250 galM3 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
HEGIFEPM_00173 0.0 lacP - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
HEGIFEPM_00174 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
HEGIFEPM_00175 6.68e-238 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
HEGIFEPM_00176 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
HEGIFEPM_00177 1.65e-286 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HEGIFEPM_00178 1.26e-245 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
HEGIFEPM_00179 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
HEGIFEPM_00180 1.19e-234 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HEGIFEPM_00181 3.4e-100 - - - K ko:K07726 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
HEGIFEPM_00182 1.12e-142 fic - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
HEGIFEPM_00183 3.71e-235 - - - K - - - helix_turn_helix, arabinose operon control protein
HEGIFEPM_00184 5.06e-298 - - - P ko:K06610 - ko00000,ko02000 Major Facilitator Superfamily
HEGIFEPM_00185 0.0 ram2 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HEGIFEPM_00186 3.03e-295 - - - P ko:K06610 - ko00000,ko02000 Sugar (and other) transporter
HEGIFEPM_00187 0.0 - 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HEGIFEPM_00188 6.72e-242 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HEGIFEPM_00189 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
HEGIFEPM_00190 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
HEGIFEPM_00191 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HEGIFEPM_00192 0.0 ubiB - - S ko:K03688 - ko00000 ABC1 family
HEGIFEPM_00193 1.95e-140 aqpZ - - U ko:K06188 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HEGIFEPM_00194 4.03e-283 - - - S - - - associated with various cellular activities
HEGIFEPM_00195 1.21e-315 - - - S - - - Putative metallopeptidase domain
HEGIFEPM_00196 1.03e-65 - - - - - - - -
HEGIFEPM_00197 1.72e-135 yezE - - K ko:K16137 - ko00000,ko03000 Bacterial regulatory proteins, tetR family
HEGIFEPM_00198 7.83e-60 - - - - - - - -
HEGIFEPM_00199 4.23e-129 - - - S - - - WxL domain surface cell wall-binding
HEGIFEPM_00200 7.12e-159 - - - S - - - WxL domain surface cell wall-binding
HEGIFEPM_00201 1.83e-235 - - - S - - - Cell surface protein
HEGIFEPM_00202 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
HEGIFEPM_00203 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
HEGIFEPM_00204 5.23e-107 yoaA - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HEGIFEPM_00205 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
HEGIFEPM_00206 1.82e-152 rcfA - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
HEGIFEPM_00207 2.98e-44 copZ - - P - - - Heavy-metal-associated domain
HEGIFEPM_00208 4.27e-126 dpsB - - P - - - Belongs to the Dps family
HEGIFEPM_00209 1.01e-26 - - - - - - - -
HEGIFEPM_00210 4.82e-55 yrkD - - S - - - Metal-sensitive transcriptional repressor
HEGIFEPM_00211 5.73e-73 trxA3 - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Thioredoxin-like domain
HEGIFEPM_00212 5.69e-184 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HEGIFEPM_00213 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
HEGIFEPM_00214 1.77e-235 - - - E - - - GDSL-like Lipase/Acylhydrolase family
HEGIFEPM_00215 7.76e-168 - - - S - - - Gram-negative-bacterium-type cell wall biogenesis
HEGIFEPM_00216 5.92e-175 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HEGIFEPM_00217 1.19e-230 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
HEGIFEPM_00218 1.37e-135 - - - K - - - transcriptional regulator
HEGIFEPM_00219 5.87e-207 - - - S ko:K07045 - ko00000 Amidohydrolase
HEGIFEPM_00220 1.43e-67 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2316)
HEGIFEPM_00221 5.13e-138 - - - - - - - -
HEGIFEPM_00223 5.77e-81 - - - - - - - -
HEGIFEPM_00224 6.18e-71 - - - - - - - -
HEGIFEPM_00225 2.04e-107 - - - M - - - PFAM NLP P60 protein
HEGIFEPM_00226 0.0 gadB 4.1.1.15, 4.1.2.27 - E ko:K01580,ko:K01634 ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940 ko00000,ko00001,ko00002,ko01000 Belongs to the group II decarboxylase family
HEGIFEPM_00227 4.45e-38 - - - - - - - -
HEGIFEPM_00228 0.0 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
HEGIFEPM_00229 3.81e-150 - - - K - - - Bacterial regulatory proteins, tetR family
HEGIFEPM_00230 1.31e-114 - - - K - - - Winged helix DNA-binding domain
HEGIFEPM_00231 1.63e-176 yesN - - T ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
HEGIFEPM_00232 5.48e-171 - - - S - - - WxL domain surface cell wall-binding
HEGIFEPM_00233 1.36e-245 - - - S - - - Bacterial protein of unknown function (DUF916)
HEGIFEPM_00234 0.0 - - - - - - - -
HEGIFEPM_00235 2.41e-212 - - - S - - - Protein of unknown function (DUF1002)
HEGIFEPM_00236 1.58e-66 - - - - - - - -
HEGIFEPM_00237 6.47e-124 - - - K ko:K22041 - ko00000,ko03000 transcriptional regulator
HEGIFEPM_00238 2.42e-117 ymdB - - S - - - Macro domain protein
HEGIFEPM_00239 2.69e-190 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HEGIFEPM_00240 1.05e-56 - - - S - - - Protein of unknown function (DUF1093)
HEGIFEPM_00241 2.07e-102 - - - S - - - Threonine/Serine exporter, ThrE
HEGIFEPM_00242 2.11e-170 - - - S - - - Putative threonine/serine exporter
HEGIFEPM_00243 1.36e-209 yvgN - - C - - - Aldo keto reductase
HEGIFEPM_00244 2.8e-205 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
HEGIFEPM_00245 0.0 yfkN 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HEGIFEPM_00246 0.0 pacL3 3.6.3.8 - P ko:K01537 - ko00000,ko01000 Cation transporter/ATPase, N-terminus
HEGIFEPM_00247 1.14e-110 - - - F - - - Nucleoside 2-deoxyribosyltransferase
HEGIFEPM_00248 6.1e-101 - - - K - - - Domain of unknown function (DUF1836)
HEGIFEPM_00249 4.21e-231 ybcH - - D ko:K06889 - ko00000 Alpha beta
HEGIFEPM_00250 1.77e-282 mdtG - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
HEGIFEPM_00251 0.0 - - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
HEGIFEPM_00252 1.02e-83 - - - S - - - Protein of unknown function (DUF1398)
HEGIFEPM_00253 8.55e-64 - - - - - - - -
HEGIFEPM_00254 7.21e-35 - - - - - - - -
HEGIFEPM_00255 2.52e-314 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
HEGIFEPM_00256 2.07e-97 - - - S - - - COG NOG18757 non supervised orthologous group
HEGIFEPM_00257 4.26e-54 - - - - - - - -
HEGIFEPM_00258 4.83e-98 copR - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
HEGIFEPM_00259 0.0 copB 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
HEGIFEPM_00260 5.12e-242 pva2 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
HEGIFEPM_00261 2.55e-145 - - - S - - - VIT family
HEGIFEPM_00262 2.66e-155 - - - S - - - membrane
HEGIFEPM_00263 1.63e-203 - - - EG - - - EamA-like transporter family
HEGIFEPM_00264 2.52e-107 - - - S ko:K02348 - ko00000 GNAT family
HEGIFEPM_00265 3.57e-150 - - - GM - - - NmrA-like family
HEGIFEPM_00266 4.79e-21 - - - - - - - -
HEGIFEPM_00267 2.27e-74 - - - - - - - -
HEGIFEPM_00268 3.22e-103 hsp3 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HEGIFEPM_00269 1.36e-112 - - - - - - - -
HEGIFEPM_00270 2.11e-82 - - - - - - - -
HEGIFEPM_00271 4.98e-275 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific adenine glycosylase
HEGIFEPM_00272 1.7e-70 - - - - - - - -
HEGIFEPM_00273 3.46e-87 yeaO - - S - - - Protein of unknown function, DUF488
HEGIFEPM_00274 9.97e-94 spxA - - P ko:K16509 - ko00000 ArsC family
HEGIFEPM_00275 2.71e-89 - - - K ko:K22296 - ko00000,ko03000 Winged helix DNA-binding domain
HEGIFEPM_00276 9.19e-208 - - - GM - - - NmrA-like family
HEGIFEPM_00277 1.25e-107 pgpA - - I - - - Phosphatidylglycerophosphatase A
HEGIFEPM_00278 3.61e-213 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HEGIFEPM_00279 4.2e-17 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
HEGIFEPM_00280 5.04e-258 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
HEGIFEPM_00281 6.91e-314 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
HEGIFEPM_00282 2.17e-35 - - - S - - - Belongs to the LOG family
HEGIFEPM_00283 5.01e-256 glmS2 - - M - - - SIS domain
HEGIFEPM_00284 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HEGIFEPM_00285 9.53e-285 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
HEGIFEPM_00286 9.84e-162 - - - S - - - YjbR
HEGIFEPM_00288 0.0 cadA - - P - - - P-type ATPase
HEGIFEPM_00289 0.0 - - - U ko:K03451 - ko00000 Belongs to the BCCT transporter (TC 2.A.15) family
HEGIFEPM_00290 1.3e-157 - - - E - - - GDSL-like Lipase/Acylhydrolase family
HEGIFEPM_00291 4.29e-101 - - - - - - - -
HEGIFEPM_00292 5.09e-51 - - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
HEGIFEPM_00293 2.42e-127 - - - FG - - - HIT domain
HEGIFEPM_00294 7.39e-224 ydhF - - S - - - Aldo keto reductase
HEGIFEPM_00295 5.17e-70 - - - S - - - Pfam:DUF59
HEGIFEPM_00296 1.12e-206 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HEGIFEPM_00297 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
HEGIFEPM_00298 1.87e-249 - - - V - - - Beta-lactamase
HEGIFEPM_00299 2.16e-124 - - - V - - - VanZ like family
HEGIFEPM_00300 1.35e-55 - - - S - - - COG NOG38524 non supervised orthologous group
HEGIFEPM_00301 1.3e-53 - - - - - - - -
HEGIFEPM_00303 8.83e-317 - - - EGP - - - Major Facilitator
HEGIFEPM_00304 5.61e-216 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HEGIFEPM_00305 4.26e-109 cvpA - - S - - - Colicin V production protein
HEGIFEPM_00306 9.61e-84 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HEGIFEPM_00307 1.59e-121 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HEGIFEPM_00308 1.8e-134 folE 2.7.6.3, 3.5.4.16 - F ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase 1
HEGIFEPM_00309 0.0 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
HEGIFEPM_00310 4.4e-138 folQ 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
HEGIFEPM_00311 4.79e-272 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 dihydropteroate synthase
HEGIFEPM_00312 3.91e-124 tag2 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
HEGIFEPM_00313 8.03e-28 - - - - - - - -
HEGIFEPM_00315 1.34e-132 - - - K - - - Helix-turn-helix XRE-family like proteins
HEGIFEPM_00316 1.3e-207 czcD - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
HEGIFEPM_00317 7.27e-73 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
HEGIFEPM_00318 2.94e-149 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
HEGIFEPM_00319 2.8e-60 qacH - - U ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
HEGIFEPM_00320 1.15e-77 - - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
HEGIFEPM_00321 6.83e-276 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
HEGIFEPM_00322 1.54e-228 ydbI - - K - - - AI-2E family transporter
HEGIFEPM_00323 1.07e-211 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HEGIFEPM_00324 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
HEGIFEPM_00326 0.0 yhdG - - E ko:K03294 - ko00000 C-terminus of AA_permease
HEGIFEPM_00327 1.88e-106 - - - - - - - -
HEGIFEPM_00329 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HEGIFEPM_00330 2.5e-188 ptp2 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
HEGIFEPM_00331 0.0 amiA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
HEGIFEPM_00332 0.0 amiC - - U ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HEGIFEPM_00333 6.22e-201 - - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEGIFEPM_00334 4.72e-244 oppD - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HEGIFEPM_00335 5.45e-182 amiF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Oligopeptide/dipeptide transporter, C-terminal region
HEGIFEPM_00336 7.21e-236 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HEGIFEPM_00337 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HEGIFEPM_00338 2.14e-314 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HEGIFEPM_00339 2.49e-73 - - - S - - - Enterocin A Immunity
HEGIFEPM_00340 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
HEGIFEPM_00341 4.27e-253 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
HEGIFEPM_00342 9.07e-233 - - - D ko:K06889 - ko00000 Alpha beta
HEGIFEPM_00343 1.04e-212 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Squalene/phytoene synthase
HEGIFEPM_00344 0.0 - 1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31 - Q ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 ko00000,ko00001,ko01000 Flavin containing amine oxidoreductase
HEGIFEPM_00345 3.06e-58 - - - L - - - Belongs to the 'phage' integrase family
HEGIFEPM_00350 5.86e-31 - - - - - - - -
HEGIFEPM_00354 2.05e-105 - - - K - - - Peptidase S24-like
HEGIFEPM_00356 3.9e-49 - - - S - - - ORF6C domain
HEGIFEPM_00357 2.05e-31 - - - S - - - DNA binding
HEGIFEPM_00368 4.82e-134 - - - L - - - DnaD domain protein
HEGIFEPM_00369 4.05e-209 pi346 - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
HEGIFEPM_00371 5.61e-64 - - - - - - - -
HEGIFEPM_00373 1.75e-21 - - - - - - - -
HEGIFEPM_00375 5.82e-26 - - - S - - - YopX protein
HEGIFEPM_00376 2.67e-24 - - - - - - - -
HEGIFEPM_00377 1.38e-83 - - - S - - - Transcriptional regulator, RinA family
HEGIFEPM_00381 7.06e-20 - - - - - - - -
HEGIFEPM_00384 1.21e-79 - - - V - - - HNH nucleases
HEGIFEPM_00385 1.8e-50 - - - L - - - Phage terminase, small subunit
HEGIFEPM_00386 0.0 terL - - S - - - overlaps another CDS with the same product name
HEGIFEPM_00388 1.72e-180 - - - S - - - Phage portal protein
HEGIFEPM_00389 4.7e-100 - 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
HEGIFEPM_00390 6.65e-148 - - - S - - - Phage capsid family
HEGIFEPM_00391 5.83e-31 - - - S - - - Phage gp6-like head-tail connector protein
HEGIFEPM_00392 3.13e-17 - - - S - - - Phage head-tail joining protein
HEGIFEPM_00393 4.57e-37 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
HEGIFEPM_00394 8.79e-31 - - - S - - - Protein of unknown function (DUF806)
HEGIFEPM_00395 5.65e-94 - - - S - - - Phage tail tube protein
HEGIFEPM_00396 5.31e-19 - - - S - - - Phage tail assembly chaperone proteins, TAC
HEGIFEPM_00398 1.21e-257 - - - L - - - Phage tail tape measure protein TP901
HEGIFEPM_00399 1.17e-285 - - - S - - - Phage tail protein
HEGIFEPM_00400 0.0 - - - S - - - Phage minor structural protein
HEGIFEPM_00401 2.1e-122 - - - - - - - -
HEGIFEPM_00404 6.33e-74 - - - - - - - -
HEGIFEPM_00405 8.25e-225 - - - M - - - Glycosyl hydrolases family 25
HEGIFEPM_00406 3.19e-50 - - - S - - - Haemolysin XhlA
HEGIFEPM_00408 1.48e-152 yugP - - S ko:K06973 - ko00000 Putative neutral zinc metallopeptidase
HEGIFEPM_00409 1.03e-34 - - - - - - - -
HEGIFEPM_00410 3.84e-186 WQ51_01275 - - S - - - EDD domain protein, DegV family
HEGIFEPM_00411 2.88e-164 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 LrgB-like family
HEGIFEPM_00412 4.14e-84 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 LrgA family
HEGIFEPM_00413 2.8e-135 - - - J - - - Acetyltransferase (GNAT) domain
HEGIFEPM_00414 4.06e-180 - 3.1.4.17, 3.1.4.53 - S ko:K01120,ko:K03651 ko00230,ko02025,map00230,map02025 ko00000,ko00001,ko01000 Calcineurin-like phosphoesterase
HEGIFEPM_00415 6.46e-49 - - - S - - - Phospholipase_D-nuclease N-terminal
HEGIFEPM_00416 2.13e-76 - - - S - - - Enterocin A Immunity
HEGIFEPM_00417 1.55e-114 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
HEGIFEPM_00418 3.32e-135 - - - - - - - -
HEGIFEPM_00419 8.44e-304 - - - S - - - module of peptide synthetase
HEGIFEPM_00420 8.66e-130 - - - S - - - NADPH-dependent FMN reductase
HEGIFEPM_00422 1.25e-164 nth2 - - L ko:K07457 - ko00000 Base excision DNA repair protein, HhH-GPD family
HEGIFEPM_00423 0.0 pts28ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HEGIFEPM_00424 2.16e-199 - - - GM - - - NmrA-like family
HEGIFEPM_00425 4.08e-101 - - - K - - - MerR family regulatory protein
HEGIFEPM_00427 1.27e-89 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HEGIFEPM_00428 5.55e-22 - - - G ko:K11203 - ko00000,ko00002,ko02000 PTS system, fructose subfamily
HEGIFEPM_00429 2.52e-35 - 2.7.1.202 - G ko:K02769 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HEGIFEPM_00430 6.69e-155 fptC - - U ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 Phosphotransferase system, EIIC
HEGIFEPM_00431 0.0 mngB 3.2.1.170 GH38 G ko:K15524 - ko00000,ko01000 Glycosyl hydrolases family 38 N-terminal domain
HEGIFEPM_00432 1.29e-115 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
HEGIFEPM_00433 6.12e-191 - - - S - - - haloacid dehalogenase-like hydrolase
HEGIFEPM_00434 6.9e-197 qorB 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NmrA-like family
HEGIFEPM_00435 6.26e-101 - - - - - - - -
HEGIFEPM_00436 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HEGIFEPM_00437 2.93e-151 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HEGIFEPM_00438 2.44e-165 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
HEGIFEPM_00439 3.73e-263 - - - S - - - DUF218 domain
HEGIFEPM_00440 2.6e-233 purR2 - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
HEGIFEPM_00441 0.0 malL 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
HEGIFEPM_00442 1.53e-244 pts26BCA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HEGIFEPM_00443 1.27e-164 pts26BCA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HEGIFEPM_00444 1.53e-198 - - - S - - - Putative adhesin
HEGIFEPM_00445 6.03e-133 - - - S - - - Protein of unknown function (DUF1700)
HEGIFEPM_00446 8.52e-70 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator
HEGIFEPM_00447 8.83e-127 - - - KT - - - response to antibiotic
HEGIFEPM_00448 1.26e-161 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
HEGIFEPM_00449 3.02e-176 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HEGIFEPM_00450 2.11e-158 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HEGIFEPM_00451 1.11e-169 fliY - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
HEGIFEPM_00452 1.2e-301 - - - EK - - - Aminotransferase, class I
HEGIFEPM_00453 1.37e-215 - - - K - - - LysR substrate binding domain
HEGIFEPM_00454 4.99e-187 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HEGIFEPM_00455 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
HEGIFEPM_00456 1.66e-288 nupG - - F ko:K16323 - ko00000,ko02000 Nucleoside
HEGIFEPM_00457 1.81e-168 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
HEGIFEPM_00458 7.39e-192 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HEGIFEPM_00459 1.01e-175 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
HEGIFEPM_00460 6.14e-202 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HEGIFEPM_00461 4.02e-40 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
HEGIFEPM_00462 6.6e-255 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HEGIFEPM_00463 3.49e-160 - - - S - - - Protein of unknown function (DUF1129)
HEGIFEPM_00464 4.08e-269 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HEGIFEPM_00465 3.84e-207 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HEGIFEPM_00466 2.4e-161 - - - S - - - Protein of unknown function (DUF1275)
HEGIFEPM_00467 6.6e-159 vanR - - K - - - response regulator
HEGIFEPM_00468 5.61e-273 hpk31 - - T - - - Histidine kinase
HEGIFEPM_00469 5.36e-305 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HEGIFEPM_00470 1.66e-116 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
HEGIFEPM_00471 2.05e-167 - - - E - - - branched-chain amino acid
HEGIFEPM_00472 5.93e-73 - - - S - - - branched-chain amino acid
HEGIFEPM_00473 1.18e-141 - - - S ko:K07090 - ko00000 membrane transporter protein
HEGIFEPM_00474 2.12e-72 - - - - - - - -
HEGIFEPM_00475 9.69e-99 - - - S - - - Psort location Cytoplasmic, score
HEGIFEPM_00476 2.47e-125 - - - S - - - Domain of unknown function (DUF4352)
HEGIFEPM_00477 5.03e-37 - - - S - - - Protein of unknown function (DUF4064)
HEGIFEPM_00478 1.66e-259 pkn2 - - KLT - - - Protein tyrosine kinase
HEGIFEPM_00479 1.41e-211 - - - - - - - -
HEGIFEPM_00480 3.66e-295 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
HEGIFEPM_00481 4.93e-149 - - - - - - - -
HEGIFEPM_00482 7.62e-270 xylR - - GK - - - ROK family
HEGIFEPM_00483 9.26e-233 ydbI - - K - - - AI-2E family transporter
HEGIFEPM_00484 5.06e-168 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HEGIFEPM_00485 6.79e-53 - - - - - - - -
HEGIFEPM_00487 8.53e-45 - - - L ko:K07483 - ko00000 transposase activity
HEGIFEPM_00488 1.34e-05 - - - L ko:K07483 - ko00000 transposase activity
HEGIFEPM_00489 7.9e-136 - - - K - - - Bacterial regulatory proteins, tetR family
HEGIFEPM_00490 2.52e-85 - - - S - - - Domain of unknown function (DUF4440)
HEGIFEPM_00491 0.0 qacA - - EGP - - - Fungal trichothecene efflux pump (TRI12)
HEGIFEPM_00492 5.35e-102 - - - GM - - - SnoaL-like domain
HEGIFEPM_00493 1.93e-139 - - - GM - - - NAD(P)H-binding
HEGIFEPM_00494 8.09e-142 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
HEGIFEPM_00495 1.44e-148 yciB - - M - - - ErfK YbiS YcfS YnhG
HEGIFEPM_00496 3.64e-47 - - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HEGIFEPM_00497 9.09e-260 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
HEGIFEPM_00498 5.31e-66 - - - K - - - Helix-turn-helix domain
HEGIFEPM_00499 2.06e-81 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
HEGIFEPM_00500 7.55e-76 - - - - - - - -
HEGIFEPM_00501 1.35e-55 - - - K - - - HxlR-like helix-turn-helix
HEGIFEPM_00502 5.35e-139 yoaZ - - S - - - intracellular protease amidase
HEGIFEPM_00503 2.97e-59 - - - S - - - Protein of unknown function (DUF3781)
HEGIFEPM_00504 8.12e-282 - - - S - - - Membrane
HEGIFEPM_00505 5.98e-85 - - - S - - - Protein of unknown function (DUF1093)
HEGIFEPM_00506 4.83e-31 - - - K - - - helix_turn_helix, mercury resistance
HEGIFEPM_00507 5.61e-54 pcaC 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
HEGIFEPM_00508 5.15e-16 - - - - - - - -
HEGIFEPM_00509 2.09e-85 - - - - - - - -
HEGIFEPM_00510 1.47e-315 celD - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEGIFEPM_00511 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HEGIFEPM_00512 1.9e-148 - - - K ko:K03489 - ko00000,ko03000 UTRA
HEGIFEPM_00513 9.82e-111 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
HEGIFEPM_00514 0.0 - - - S - - - MucBP domain
HEGIFEPM_00515 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
HEGIFEPM_00516 1.16e-209 - - - K - - - LysR substrate binding domain
HEGIFEPM_00517 3.73e-201 - 3.6.1.22 - L ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 ko00000,ko00001,ko01000 NADH pyrophosphatase zinc ribbon domain
HEGIFEPM_00518 4.99e-238 nhaP4 - - P ko:K03316 - ko00000 Sodium proton antiporter
HEGIFEPM_00519 1.97e-111 nhaP4 - - P ko:K03316 - ko00000 Sodium proton antiporter
HEGIFEPM_00520 0.0 lepA2 - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HEGIFEPM_00521 2.4e-152 - - - K - - - Bacterial regulatory proteins, tetR family
HEGIFEPM_00522 1.23e-268 - - - NU - - - Mycoplasma protein of unknown function, DUF285
HEGIFEPM_00523 1.1e-115 - - - S - - - WxL domain surface cell wall-binding
HEGIFEPM_00524 2.22e-235 - - - S - - - Bacterial protein of unknown function (DUF916)
HEGIFEPM_00525 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
HEGIFEPM_00526 3.86e-85 - - - K - - - helix_turn_helix, mercury resistance
HEGIFEPM_00527 6.38e-195 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
HEGIFEPM_00528 1.4e-96 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
HEGIFEPM_00529 2.47e-168 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HEGIFEPM_00530 6.73e-211 - - - GM - - - NmrA-like family
HEGIFEPM_00531 3.74e-120 - - - K - - - Bacterial regulatory proteins, tetR family
HEGIFEPM_00532 2.34e-219 fhuG - - U ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEGIFEPM_00533 1.81e-228 fhuB - - U ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEGIFEPM_00534 6.37e-188 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HEGIFEPM_00535 1.22e-219 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
HEGIFEPM_00536 2.64e-141 - - - K - - - Bacterial regulatory proteins, tetR family
HEGIFEPM_00537 0.0 yfjF - - U - - - Sugar (and other) transporter
HEGIFEPM_00538 1.97e-229 ydhF - - S - - - Aldo keto reductase
HEGIFEPM_00539 1.09e-130 - - - S - - - Protein of unknown function (DUF1211)
HEGIFEPM_00540 3.47e-244 - 1.1.1.219 - GM ko:K00091 - ko00000,ko01000 Male sterility protein
HEGIFEPM_00541 1.17e-125 - - - K - - - Bacterial regulatory proteins, tetR family
HEGIFEPM_00542 1.22e-165 - - - S - - - KR domain
HEGIFEPM_00543 3.36e-74 - - - K - - - HxlR-like helix-turn-helix
HEGIFEPM_00544 1.62e-62 - - - S - - - Domain of unknown function (DUF1905)
HEGIFEPM_00545 1.18e-15 - - - M - - - Glycosyl hydrolases family 25
HEGIFEPM_00546 0.0 - - - M - - - Glycosyl hydrolases family 25
HEGIFEPM_00547 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HEGIFEPM_00548 2.65e-216 - - - GM - - - NmrA-like family
HEGIFEPM_00549 1.59e-130 - - - K - - - Bacterial regulatory proteins, tetR family
HEGIFEPM_00550 3.51e-212 blpH 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
HEGIFEPM_00551 1.38e-174 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
HEGIFEPM_00552 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
HEGIFEPM_00553 7.81e-148 - - - M - - - ErfK YbiS YcfS YnhG
HEGIFEPM_00554 1.81e-272 - - - EGP - - - Major Facilitator
HEGIFEPM_00555 3.25e-81 ytcD - - K - - - Transcriptional regulator, HxlR family
HEGIFEPM_00556 4.31e-149 - - - S - - - Haloacid dehalogenase-like hydrolase
HEGIFEPM_00557 4.13e-157 - - - - - - - -
HEGIFEPM_00558 1.95e-288 - - - NU - - - Mycoplasma protein of unknown function, DUF285
HEGIFEPM_00559 1.56e-129 - - - S - - - WxL domain surface cell wall-binding
HEGIFEPM_00560 1.59e-243 ynjC - - S - - - Cell surface protein
HEGIFEPM_00561 2.4e-123 - - - S - - - GyrI-like small molecule binding domain
HEGIFEPM_00562 1.27e-90 - - - S - - - Iron-sulphur cluster biosynthesis
HEGIFEPM_00563 1.88e-225 - - - C - - - Alcohol dehydrogenase GroES-like domain
HEGIFEPM_00564 3.48e-136 - - - S - - - WxL domain surface cell wall-binding
HEGIFEPM_00565 2.07e-240 - - - S - - - Cell surface protein
HEGIFEPM_00566 3.15e-98 - - - - - - - -
HEGIFEPM_00567 0.0 - - - - - - - -
HEGIFEPM_00568 3.05e-289 hpk9 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
HEGIFEPM_00569 1.47e-51 - - - S ko:K07343 - ko00000 TfoX C-terminal domain
HEGIFEPM_00570 2.81e-181 - - - K - - - Helix-turn-helix domain
HEGIFEPM_00571 0.0 aapA - - M - - - Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HEGIFEPM_00572 1.36e-84 - - - S - - - Cupredoxin-like domain
HEGIFEPM_00573 7.11e-57 - - - S - - - Cupredoxin-like domain
HEGIFEPM_00574 0.0 copA 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
HEGIFEPM_00575 1.13e-270 adhC 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
HEGIFEPM_00576 6.97e-285 dhaT 1.1.1.202 - C ko:K00086 ko00561,ko00640,map00561,map00640 ko00000,ko00001,ko01000 Dehydrogenase
HEGIFEPM_00577 1.67e-86 lysM - - M - - - LysM domain
HEGIFEPM_00578 0.0 - - - E - - - Amino Acid
HEGIFEPM_00579 5.2e-187 - - - K - - - Helix-turn-helix XRE-family like proteins
HEGIFEPM_00580 5.65e-92 - - - - - - - -
HEGIFEPM_00582 8.48e-209 yhxD - - IQ - - - KR domain
HEGIFEPM_00583 3.23e-290 amd - - E - - - Peptidase family M20/M25/M40
HEGIFEPM_00584 1.3e-226 - - - O - - - protein import
HEGIFEPM_00585 0.0 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HEGIFEPM_00586 0.0 - - - V ko:K06147,ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HEGIFEPM_00587 2.31e-277 - - - - - - - -
HEGIFEPM_00588 3.41e-151 - - - GM - - - NAD(P)H-binding
HEGIFEPM_00589 3.83e-178 gdh 1.1.1.47, 1.1.1.53 - IQ ko:K00034,ko:K00038 ko00030,ko00140,ko01100,ko01120,ko01200,map00030,map00140,map01100,map01120,map01200 ko00000,ko00001,ko01000 reductase
HEGIFEPM_00590 3.55e-79 - - - I - - - sulfurtransferase activity
HEGIFEPM_00591 6.7e-102 yphH - - S - - - Cupin domain
HEGIFEPM_00592 1.17e-120 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
HEGIFEPM_00593 3.57e-150 - - - GM - - - NAD(P)H-binding
HEGIFEPM_00594 1.88e-222 - - - C - - - C4-dicarboxylate transmembrane transporter activity
HEGIFEPM_00595 6.54e-168 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HEGIFEPM_00596 4.63e-91 - - - - - - - -
HEGIFEPM_00597 2.02e-215 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
HEGIFEPM_00598 0.0 umuC - - L ko:K03502 - ko00000,ko03400 impB/mucB/samB family C-terminal domain
HEGIFEPM_00599 7.43e-97 - - - S - - - Psort location Cytoplasmic, score
HEGIFEPM_00600 3.55e-281 - - - T - - - diguanylate cyclase
HEGIFEPM_00601 2.72e-155 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Methyladenine glycosylase
HEGIFEPM_00602 2.06e-119 - - - - - - - -
HEGIFEPM_00603 5.76e-212 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HEGIFEPM_00604 1.58e-72 nudA - - S - - - ASCH
HEGIFEPM_00605 1.91e-136 - - - S - - - SdpI/YhfL protein family
HEGIFEPM_00606 3.03e-130 - - - M - - - Lysin motif
HEGIFEPM_00607 4.61e-101 - - - M - - - LysM domain
HEGIFEPM_00608 2.1e-99 - - - K - - - helix_turn_helix, mercury resistance
HEGIFEPM_00609 1.57e-237 - - - GM - - - Male sterility protein
HEGIFEPM_00610 0.0 pbg6 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HEGIFEPM_00611 0.0 pts23C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEGIFEPM_00612 7.47e-70 ptcB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HEGIFEPM_00613 3.91e-100 pts23A - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HEGIFEPM_00614 1.24e-194 - - - K - - - Helix-turn-helix domain
HEGIFEPM_00615 1.72e-73 - - - - - - - -
HEGIFEPM_00616 7.85e-205 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
HEGIFEPM_00617 2.03e-84 - - - - - - - -
HEGIFEPM_00618 0.0 - - - P - - - Concanavalin A-like lectin/glucanases superfamily
HEGIFEPM_00619 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HEGIFEPM_00620 4.57e-123 - - - P - - - Cadmium resistance transporter
HEGIFEPM_00621 8.58e-65 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
HEGIFEPM_00622 1.81e-150 - - - S - - - SNARE associated Golgi protein
HEGIFEPM_00623 7.03e-62 - - - - - - - -
HEGIFEPM_00624 2.94e-83 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HEGIFEPM_00625 4.78e-109 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HEGIFEPM_00626 1.48e-107 - - - K - - - Helix-turn-helix XRE-family like proteins
HEGIFEPM_00627 2.88e-106 gtcA3 - - S - - - GtrA-like protein
HEGIFEPM_00628 2.93e-169 zmp3 - - O - - - Zinc-dependent metalloprotease
HEGIFEPM_00629 1.15e-43 - - - - - - - -
HEGIFEPM_00631 1.04e-269 livJ - - E ko:K01999 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Receptor family ligand binding region
HEGIFEPM_00632 1.96e-196 livH - - U ko:K01997 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
HEGIFEPM_00633 1.88e-192 livM - - E ko:K01997,ko:K01998 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
HEGIFEPM_00634 1.28e-180 livG - - E ko:K01995 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid ATP-binding cassette transporter
HEGIFEPM_00635 2.78e-158 livF - - E ko:K01996 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
HEGIFEPM_00636 4.5e-123 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
HEGIFEPM_00637 1.27e-137 - - - S - - - WxL domain surface cell wall-binding
HEGIFEPM_00638 4.54e-241 - - - S - - - Cell surface protein
HEGIFEPM_00639 1.4e-82 - - - - - - - -
HEGIFEPM_00640 0.0 - - - - - - - -
HEGIFEPM_00641 7.28e-218 XK27_00670 - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
HEGIFEPM_00642 2.48e-199 WQ51_06230 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HEGIFEPM_00643 6.24e-152 - - - S ko:K05833 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HEGIFEPM_00644 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.208 - G ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
HEGIFEPM_00645 8.08e-154 ydgI3 - - C - - - Nitroreductase family
HEGIFEPM_00646 1.9e-126 - - - K - - - Transcriptional regulator, MarR family
HEGIFEPM_00647 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
HEGIFEPM_00648 3.73e-207 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
HEGIFEPM_00649 8.76e-63 - - - K - - - HxlR-like helix-turn-helix
HEGIFEPM_00650 6.17e-146 - - - K - - - Transcriptional regulator C-terminal region
HEGIFEPM_00651 1.44e-226 - 4.1.1.52 - S ko:K22213 - ko00000,ko01000 Amidohydrolase
HEGIFEPM_00652 3.03e-166 - - - E - - - lipolytic protein G-D-S-L family
HEGIFEPM_00653 3.43e-206 yicL - - EG - - - EamA-like transporter family
HEGIFEPM_00654 1.21e-298 - - - M - - - Collagen binding domain
HEGIFEPM_00655 0.0 - - - I - - - acetylesterase activity
HEGIFEPM_00656 4.07e-232 - - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
HEGIFEPM_00657 7.11e-173 - - - S ko:K06889 - ko00000 Alpha/beta hydrolase family
HEGIFEPM_00658 4.29e-50 - - - - - - - -
HEGIFEPM_00660 3.93e-182 - - - S - - - zinc-ribbon domain
HEGIFEPM_00661 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
HEGIFEPM_00662 0.0 - 4.1.1.98 - H ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HEGIFEPM_00663 4.34e-314 - - - P - - - Sodium:sulfate symporter transmembrane region
HEGIFEPM_00664 5.12e-212 - - - K - - - LysR substrate binding domain
HEGIFEPM_00665 1.84e-134 - - - - - - - -
HEGIFEPM_00666 3.7e-30 - - - - - - - -
HEGIFEPM_00667 1.26e-245 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HEGIFEPM_00668 3.21e-243 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HEGIFEPM_00669 5.97e-96 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
HEGIFEPM_00670 1.56e-108 - - - - - - - -
HEGIFEPM_00671 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
HEGIFEPM_00672 3.83e-135 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HEGIFEPM_00673 3.1e-54 - - - T - - - Putative diguanylate phosphodiesterase
HEGIFEPM_00674 1.11e-95 - - - T - - - Putative diguanylate phosphodiesterase
HEGIFEPM_00675 2.05e-279 - - - T - - - Diguanylate cyclase, GGDEF domain
HEGIFEPM_00676 8.68e-118 pts21A - - G ko:K02755 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HEGIFEPM_00677 2e-52 - - - S - - - Cytochrome B5
HEGIFEPM_00678 0.0 - - - - - - - -
HEGIFEPM_00679 5.86e-167 treR - - K ko:K03486 - ko00000,ko03000 UTRA
HEGIFEPM_00680 1.58e-203 - - - I - - - alpha/beta hydrolase fold
HEGIFEPM_00681 0.0 npp - - S - - - type I phosphodiesterase nucleotide pyrophosphatase
HEGIFEPM_00682 2.06e-297 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
HEGIFEPM_00683 0.0 - - - E ko:K03294 - ko00000 Amino acid permease
HEGIFEPM_00684 1.18e-225 - 3.4.11.5 - I ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
HEGIFEPM_00685 2.78e-222 ropB - - K - - - Helix-turn-helix XRE-family like proteins
HEGIFEPM_00686 2.54e-269 - - - EGP - - - Major facilitator Superfamily
HEGIFEPM_00687 0.0 uvrA3 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC
HEGIFEPM_00688 0.0 - - - S - - - Predicted membrane protein (DUF2207)
HEGIFEPM_00689 4.68e-190 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
HEGIFEPM_00690 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
HEGIFEPM_00691 9.53e-284 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HEGIFEPM_00692 1.31e-120 - - - M - - - Phosphotransferase enzyme family
HEGIFEPM_00693 7.2e-125 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HEGIFEPM_00694 3.69e-139 yokL3 - - J - - - Acetyltransferase (GNAT) domain
HEGIFEPM_00695 1.66e-199 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
HEGIFEPM_00696 6.88e-71 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HEGIFEPM_00697 1.59e-143 - - - K - - - Transcriptional regulator (TetR family)
HEGIFEPM_00698 2.85e-231 yhgE - - V ko:K01421 - ko00000 domain protein
HEGIFEPM_00701 8.96e-317 - - - EGP - - - Major Facilitator
HEGIFEPM_00702 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HEGIFEPM_00703 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HEGIFEPM_00705 5.17e-249 - - - C - - - Aldo/keto reductase family
HEGIFEPM_00706 1.86e-132 - - - M - - - Protein of unknown function (DUF3737)
HEGIFEPM_00707 3.31e-283 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
HEGIFEPM_00708 9.15e-132 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
HEGIFEPM_00709 1.03e-40 - - - - - - - -
HEGIFEPM_00710 7.47e-164 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
HEGIFEPM_00711 1.04e-124 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
HEGIFEPM_00712 8.55e-99 - - - T - - - Belongs to the universal stress protein A family
HEGIFEPM_00714 5.85e-194 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
HEGIFEPM_00715 2.03e-248 adh2 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
HEGIFEPM_00716 8.81e-135 - - - GM - - - NAD(P)H-binding
HEGIFEPM_00717 0.0 - - - L ko:K07487 - ko00000 Transposase
HEGIFEPM_00718 6.67e-204 - - - K - - - LysR substrate binding domain
HEGIFEPM_00719 1.49e-83 - - - S - - - Domain of unknown function (DUF4440)
HEGIFEPM_00720 5.46e-145 pgm8 - - G - - - Histidine phosphatase superfamily (branch 1)
HEGIFEPM_00721 2.81e-64 - - - - - - - -
HEGIFEPM_00722 2.8e-49 - - - - - - - -
HEGIFEPM_00723 4.4e-112 yvbK - - K - - - GNAT family
HEGIFEPM_00724 4.68e-109 - - - - - - - -
HEGIFEPM_00725 1.52e-144 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HEGIFEPM_00726 2.44e-149 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HEGIFEPM_00727 5.27e-140 thgA3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
HEGIFEPM_00728 2.93e-151 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HEGIFEPM_00730 2.03e-155 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HEGIFEPM_00731 0.0 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
HEGIFEPM_00732 5.3e-302 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
HEGIFEPM_00733 1.27e-103 - - - K - - - transcriptional regulator, MerR family
HEGIFEPM_00734 4.77e-100 yphH - - S - - - Cupin domain
HEGIFEPM_00735 2e-73 cmd 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
HEGIFEPM_00736 6.27e-166 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HEGIFEPM_00737 6.76e-270 natB - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HEGIFEPM_00738 4.23e-215 natA - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HEGIFEPM_00739 3.92e-120 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Methyltransferase
HEGIFEPM_00740 2.72e-90 - - - M - - - LysM domain
HEGIFEPM_00741 1.14e-79 - - - M - - - LysM domain protein
HEGIFEPM_00742 0.0 tagE6 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HEGIFEPM_00743 0.0 tagE5 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Poly(Glycerol-phosphate) alpha-glucosyltransferase
HEGIFEPM_00744 2.06e-194 rlrG - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
HEGIFEPM_00745 4.38e-222 - - - S - - - Conserved hypothetical protein 698
HEGIFEPM_00746 1.49e-131 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HEGIFEPM_00747 4.03e-104 - - - S - - - Domain of unknown function (DUF4811)
HEGIFEPM_00748 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
HEGIFEPM_00749 7.22e-163 - 3.8.1.2 - S ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
HEGIFEPM_00750 7.15e-260 - - - EGP - - - Major Facilitator Superfamily
HEGIFEPM_00751 4.86e-56 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Fumarase C C-terminus
HEGIFEPM_00752 9.98e-256 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Fumarase C C-terminus
HEGIFEPM_00753 2.11e-199 mleP3 - - S ko:K07088 - ko00000 Membrane transport protein
HEGIFEPM_00754 9.01e-155 - - - S - - - Membrane
HEGIFEPM_00755 1.14e-257 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HEGIFEPM_00756 5.04e-127 ywjB - - H - - - RibD C-terminal domain
HEGIFEPM_00757 5.72e-238 iunH3 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Inosine-uridine preferring nucleoside hydrolase
HEGIFEPM_00758 1.12e-116 - - - T ko:K16923 - ko00000,ko00002,ko02000 phosphorelay sensor kinase activity
HEGIFEPM_00759 7.14e-157 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HEGIFEPM_00760 1.63e-238 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
HEGIFEPM_00761 1.86e-123 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
HEGIFEPM_00762 3.41e-295 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HEGIFEPM_00763 9.38e-189 - - - KT - - - helix_turn_helix, mercury resistance
HEGIFEPM_00764 3.38e-150 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
HEGIFEPM_00765 1.04e-120 - - - S - - - Protein of unknown function (DUF1694)
HEGIFEPM_00766 1.57e-184 - - - S - - - Peptidase_C39 like family
HEGIFEPM_00767 1.08e-243 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
HEGIFEPM_00768 1.54e-144 - - - - - - - -
HEGIFEPM_00769 1.21e-306 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HEGIFEPM_00770 1.97e-110 - - - S - - - Pfam:DUF3816
HEGIFEPM_00771 1.35e-55 - - - S - - - COG NOG38524 non supervised orthologous group
HEGIFEPM_00773 5.3e-209 - - - K - - - Transcriptional regulator
HEGIFEPM_00774 5.11e-208 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
HEGIFEPM_00775 8.21e-212 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 Oxidoreductase, aldo keto reductase family protein
HEGIFEPM_00776 2e-100 - - - K - - - Winged helix DNA-binding domain
HEGIFEPM_00777 0.0 ycaM - - E - - - amino acid
HEGIFEPM_00778 5.59e-163 aroC1 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Type I 3-dehydroquinase
HEGIFEPM_00779 4.3e-44 - - - - - - - -
HEGIFEPM_00780 0.0 - - - M - - - Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
HEGIFEPM_00781 1.08e-81 - - - M - - - Domain of unknown function (DUF5011)
HEGIFEPM_00782 0.0 - - - M - - - Domain of unknown function (DUF5011)
HEGIFEPM_00783 1.17e-101 fld - - C ko:K03839 - ko00000 Flavodoxin
HEGIFEPM_00784 0.0 - - - - ko:K21471 - ko00000,ko01000,ko01002,ko01011 -
HEGIFEPM_00785 3.78e-132 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
HEGIFEPM_00786 4.12e-226 serA1 - - EH - - - D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HEGIFEPM_00787 3.26e-203 - - - EG - - - EamA-like transporter family
HEGIFEPM_00788 1.51e-235 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HEGIFEPM_00789 5.06e-196 - - - S - - - hydrolase
HEGIFEPM_00790 7.63e-107 - - - - - - - -
HEGIFEPM_00791 1.75e-156 pgm7 - - G - - - Phosphoglycerate mutase family
HEGIFEPM_00792 1.4e-181 epsV - - S - - - glycosyl transferase family 2
HEGIFEPM_00793 7.44e-168 gntR - - K ko:K03489 - ko00000,ko03000 UTRA
HEGIFEPM_00794 1.86e-64 pts20B 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HEGIFEPM_00795 6.7e-74 celC 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose Cellobiose specific IIA subunit
HEGIFEPM_00796 0.0 pbg5 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HEGIFEPM_00797 0.0 pbg4 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HEGIFEPM_00798 4.77e-316 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
HEGIFEPM_00799 4.29e-173 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
HEGIFEPM_00800 9.76e-234 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
HEGIFEPM_00801 2.13e-152 - - - K - - - Transcriptional regulator
HEGIFEPM_00802 0.0 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HEGIFEPM_00803 3.74e-115 yrxA - - S ko:K07105 - ko00000 3H domain
HEGIFEPM_00804 4.54e-285 - - - EGP - - - Transmembrane secretion effector
HEGIFEPM_00805 4.43e-294 - - - S - - - Sterol carrier protein domain
HEGIFEPM_00806 9.97e-269 ybhE - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
HEGIFEPM_00807 3.94e-49 XK27_01315 - - S - - - Protein of unknown function (DUF2829)
HEGIFEPM_00808 1.62e-173 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
HEGIFEPM_00809 2.26e-91 - - - FG - - - Scavenger mRNA decapping enzyme C-term binding
HEGIFEPM_00810 2.28e-132 - 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
HEGIFEPM_00811 1.76e-143 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
HEGIFEPM_00812 1.68e-37 - - - S - - - Pentapeptide repeats (8 copies)
HEGIFEPM_00813 4.65e-186 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
HEGIFEPM_00814 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
HEGIFEPM_00815 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
HEGIFEPM_00817 1.21e-69 - - - - - - - -
HEGIFEPM_00818 1.52e-151 - - - - - - - -
HEGIFEPM_00819 1.16e-110 - - - F - - - belongs to the nudix hydrolase family
HEGIFEPM_00820 3.03e-299 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
HEGIFEPM_00821 4.79e-13 - - - - - - - -
HEGIFEPM_00822 4.87e-66 - - - - - - - -
HEGIFEPM_00823 1.76e-114 - - - - - - - -
HEGIFEPM_00824 4.02e-95 gtcA - - S - - - Teichoic acid glycosylation protein
HEGIFEPM_00825 7.35e-46 - - - - - - - -
HEGIFEPM_00826 2.7e-104 usp5 - - T - - - universal stress protein
HEGIFEPM_00827 3.41e-190 - - - - - - - -
HEGIFEPM_00828 7.89e-212 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HEGIFEPM_00829 8.2e-81 - - - K - - - Transcriptional regulator, GntR family
HEGIFEPM_00830 4.76e-56 - - - - - - - -
HEGIFEPM_00831 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
HEGIFEPM_00832 2.05e-178 cysA - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HEGIFEPM_00833 3.7e-233 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 Asparaginase
HEGIFEPM_00834 4.15e-191 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HEGIFEPM_00835 5.95e-153 cah 4.2.1.1 - P ko:K01674 ko00910,map00910 ko00000,ko00001,ko01000 Eukaryotic-type carbonic anhydrase
HEGIFEPM_00836 2.04e-189 ptp3 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
HEGIFEPM_00837 2.01e-243 lplL 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Bacterial lipoate protein ligase C-terminus
HEGIFEPM_00838 9.92e-143 - - - S - - - NADPH-dependent FMN reductase
HEGIFEPM_00839 1.31e-303 XK27_09615 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
HEGIFEPM_00840 3.77e-104 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HEGIFEPM_00841 2.87e-270 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HEGIFEPM_00842 3.39e-168 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
HEGIFEPM_00843 1.17e-55 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HEGIFEPM_00844 6.91e-164 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HEGIFEPM_00845 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HEGIFEPM_00846 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HEGIFEPM_00847 5.35e-246 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
HEGIFEPM_00848 5.35e-133 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HEGIFEPM_00849 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
HEGIFEPM_00850 2.71e-280 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
HEGIFEPM_00851 4.17e-163 - - - E - - - Methionine synthase
HEGIFEPM_00852 0.0 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
HEGIFEPM_00853 2.62e-121 - - - - - - - -
HEGIFEPM_00854 1.25e-199 - - - T - - - EAL domain
HEGIFEPM_00855 2.24e-206 - - - GM - - - NmrA-like family
HEGIFEPM_00856 2.31e-279 pbuG - - S ko:K06901 - ko00000,ko02000 Permease family
HEGIFEPM_00857 4.41e-305 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
HEGIFEPM_00858 0.0 pucR_2 - - QT ko:K09684 - ko00000,ko03000 Purine catabolism regulatory protein-like family
HEGIFEPM_00859 7.13e-123 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HEGIFEPM_00860 1.22e-220 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
HEGIFEPM_00861 2.38e-310 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HEGIFEPM_00862 2.76e-271 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
HEGIFEPM_00863 1.81e-109 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
HEGIFEPM_00864 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
HEGIFEPM_00865 6.03e-218 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HEGIFEPM_00866 1.09e-161 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HEGIFEPM_00867 6.64e-146 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HEGIFEPM_00868 9.03e-217 oroP - - S ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Putative inner membrane exporter, YdcZ
HEGIFEPM_00869 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HEGIFEPM_00870 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
HEGIFEPM_00871 2.24e-123 - - - K - - - Acetyltransferase (GNAT) family
HEGIFEPM_00872 1.29e-148 - - - GM - - - NAD(P)H-binding
HEGIFEPM_00873 5.73e-208 mleR - - K - - - LysR family
HEGIFEPM_00874 2.09e-169 - - - S ko:K07090 - ko00000 membrane transporter protein
HEGIFEPM_00875 3.59e-26 - - - - - - - -
HEGIFEPM_00876 1.84e-204 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HEGIFEPM_00877 1.02e-277 araT2 - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HEGIFEPM_00878 0.0 gabR - - K ko:K00375 - ko00000,ko03000 Bacterial regulatory proteins, gntR family
HEGIFEPM_00879 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HEGIFEPM_00880 4.71e-74 - - - S - - - SdpI/YhfL protein family
HEGIFEPM_00881 2.19e-220 - - - C - - - Zinc-binding dehydrogenase
HEGIFEPM_00882 2.84e-82 - - - K - - - helix_turn_helix, mercury resistance
HEGIFEPM_00883 1.17e-270 yttB - - EGP - - - Major Facilitator
HEGIFEPM_00884 0.0 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
HEGIFEPM_00885 1.18e-114 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
HEGIFEPM_00886 0.0 yhdP - - S - - - Transporter associated domain
HEGIFEPM_00887 2.97e-76 - - - - - - - -
HEGIFEPM_00888 2.61e-96 hsp2 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HEGIFEPM_00889 1.55e-79 - - - - - - - -
HEGIFEPM_00890 1.7e-118 - - - K - - - Domain of unknown function (DUF1836)
HEGIFEPM_00891 8.05e-179 rrp8 - - K - - - LytTr DNA-binding domain
HEGIFEPM_00892 1.97e-150 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HEGIFEPM_00893 6.08e-179 - - - - - - - -
HEGIFEPM_00894 4.75e-117 ybaK - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HEGIFEPM_00895 3.53e-169 - - - K - - - Transcriptional regulator
HEGIFEPM_00896 1.93e-207 - - - S - - - Putative esterase
HEGIFEPM_00897 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
HEGIFEPM_00898 1.85e-285 - - - M - - - Glycosyl transferases group 1
HEGIFEPM_00899 1.38e-30 - - - S - - - Protein of unknown function (DUF2929)
HEGIFEPM_00900 4.05e-64 - - - K - - - Cro/C1-type HTH DNA-binding domain
HEGIFEPM_00901 8.5e-98 tcaA - - S ko:K21463 - ko00000 response to antibiotic
HEGIFEPM_00902 1.09e-55 - - - S - - - zinc-ribbon domain
HEGIFEPM_00903 2.73e-24 - - - - - - - -
HEGIFEPM_00904 1.02e-202 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
HEGIFEPM_00905 1.02e-102 uspA3 - - T - - - universal stress protein
HEGIFEPM_00906 0.0 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Bacterial SH3 domain
HEGIFEPM_00907 4.26e-250 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
HEGIFEPM_00908 4.15e-78 - - - - - - - -
HEGIFEPM_00909 4.05e-98 - - - - - - - -
HEGIFEPM_00910 6.94e-106 - - - S - - - Protein of unknown function (DUF2798)
HEGIFEPM_00911 1.57e-71 - - - - - - - -
HEGIFEPM_00912 3.89e-62 - - - - - - - -
HEGIFEPM_00913 3.87e-262 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
HEGIFEPM_00914 9.89e-74 ytpP - - CO - - - Thioredoxin
HEGIFEPM_00915 1.19e-186 - - - S ko:K06889 - ko00000 Dienelactone hydrolase family
HEGIFEPM_00916 4.27e-89 - - - - - - - -
HEGIFEPM_00917 0.0 spxB 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
HEGIFEPM_00918 0.0 - - - L ko:K07487 - ko00000 Transposase
HEGIFEPM_00919 2.8e-63 - - - - - - - -
HEGIFEPM_00920 4.31e-76 - - - - - - - -
HEGIFEPM_00922 2.64e-210 - - - - - - - -
HEGIFEPM_00923 1.4e-95 - - - K - - - Transcriptional regulator
HEGIFEPM_00924 0.0 pepF2 - - E - - - Oligopeptidase F
HEGIFEPM_00925 3.25e-223 ybcH - - D ko:K06889 - ko00000 Alpha beta
HEGIFEPM_00926 2.07e-60 - - - S - - - Enterocin A Immunity
HEGIFEPM_00927 2.39e-85 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator, GntR family
HEGIFEPM_00928 5e-162 skfE - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HEGIFEPM_00929 1.54e-171 - - - - - - - -
HEGIFEPM_00930 9.38e-139 pncA - - Q - - - Isochorismatase family
HEGIFEPM_00931 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HEGIFEPM_00932 0.0 nhaP2 - - P ko:K03316 - ko00000 Sodium proton antiporter
HEGIFEPM_00933 1.55e-253 yhhX - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
HEGIFEPM_00934 1.18e-225 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
HEGIFEPM_00935 4.16e-150 - - - K - - - Helix-turn-helix domain, rpiR family
HEGIFEPM_00936 1.22e-200 ccpB - - K - - - lacI family
HEGIFEPM_00937 7.61e-154 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
HEGIFEPM_00938 3.45e-209 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HEGIFEPM_00939 1.23e-228 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
HEGIFEPM_00940 1.22e-126 - - - C - - - Nitroreductase family
HEGIFEPM_00941 6.04e-217 - - - S - - - Polyphosphate kinase 2 (PPK2)
HEGIFEPM_00942 7.24e-250 - - - S - - - domain, Protein
HEGIFEPM_00943 2.14e-183 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HEGIFEPM_00944 4.01e-236 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
HEGIFEPM_00945 0.0 glpQ4 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
HEGIFEPM_00946 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HEGIFEPM_00947 7.35e-99 yjcF - - S - - - Acetyltransferase (GNAT) domain
HEGIFEPM_00948 0.0 - - - M - - - domain protein
HEGIFEPM_00949 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
HEGIFEPM_00950 1.26e-143 - - - S - - - Protein of unknown function (DUF1211)
HEGIFEPM_00951 1.45e-46 - - - - - - - -
HEGIFEPM_00952 2.83e-238 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HEGIFEPM_00953 1.69e-255 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HEGIFEPM_00954 2.54e-17 rmeB - - K - - - transcriptional regulator, MerR family
HEGIFEPM_00955 1.71e-67 - - - S - - - Domain of unknown function (DU1801)
HEGIFEPM_00956 7.28e-213 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
HEGIFEPM_00957 3.05e-282 ysaA - - V - - - RDD family
HEGIFEPM_00958 6.46e-208 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Histidinol phosphate phosphatase, HisJ
HEGIFEPM_00959 1.33e-274 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HEGIFEPM_00960 3.98e-150 hisG 2.4.2.17 - F ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HEGIFEPM_00961 1.57e-298 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HEGIFEPM_00962 1e-138 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
HEGIFEPM_00963 2.23e-142 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HEGIFEPM_00964 6.84e-166 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HEGIFEPM_00965 1.05e-171 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HEGIFEPM_00966 2.49e-77 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HEGIFEPM_00967 1.07e-68 hisE 3.6.1.31 - E ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 phosphoribosyl-ATP diphosphatase activity
HEGIFEPM_00968 4.04e-81 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HEGIFEPM_00969 1.5e-161 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HEGIFEPM_00970 1.64e-96 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
HEGIFEPM_00971 1.01e-176 yceF - - P ko:K05794 - ko00000 membrane
HEGIFEPM_00972 2.34e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 Dehydrogenase
HEGIFEPM_00973 0.0 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
HEGIFEPM_00974 1.32e-178 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HEGIFEPM_00975 6.03e-196 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HEGIFEPM_00976 2.29e-225 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
HEGIFEPM_00977 1.26e-212 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
HEGIFEPM_00978 1.43e-310 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
HEGIFEPM_00979 1.46e-80 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Homoserine dehydrogenase
HEGIFEPM_00980 8.59e-196 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Homoserine dehydrogenase
HEGIFEPM_00981 2.84e-208 - - - S - - - Uncharacterised protein, DegV family COG1307
HEGIFEPM_00982 4.37e-241 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HEGIFEPM_00983 8.22e-178 nagE 2.7.1.193, 2.7.1.199, 2.7.1.208 - G ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
HEGIFEPM_00984 7.42e-262 nagE 2.7.1.193, 2.7.1.199, 2.7.1.208 - G ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
HEGIFEPM_00985 9.2e-62 - - - - - - - -
HEGIFEPM_00986 5.76e-107 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEGIFEPM_00987 9.24e-140 - - - K ko:K06977 - ko00000 acetyltransferase
HEGIFEPM_00988 0.0 - - - S - - - ABC transporter, ATP-binding protein
HEGIFEPM_00989 2.81e-278 - - - T - - - diguanylate cyclase
HEGIFEPM_00990 1.11e-45 - - - - - - - -
HEGIFEPM_00991 2.29e-48 - - - - - - - -
HEGIFEPM_00992 4.17e-107 - - - K ko:K03719 - ko00000,ko03000,ko03036 AsnC family
HEGIFEPM_00993 4.27e-223 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 NlpC/P60 family
HEGIFEPM_00994 8.16e-207 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HEGIFEPM_00996 2.68e-32 - - - - - - - -
HEGIFEPM_00997 8.05e-178 - - - F - - - NUDIX domain
HEGIFEPM_00998 6.83e-274 yceI - - EGP ko:K08369 - ko00000,ko02000 Major Facilitator
HEGIFEPM_00999 5.34e-64 - - - - - - - -
HEGIFEPM_01000 6.24e-120 - - - S - - - ECF-type riboflavin transporter, S component
HEGIFEPM_01002 1.26e-218 - - - EG - - - EamA-like transporter family
HEGIFEPM_01003 1.06e-51 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
HEGIFEPM_01004 2.12e-308 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
HEGIFEPM_01005 1.45e-173 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
HEGIFEPM_01006 0.0 yclK - - T - - - Histidine kinase
HEGIFEPM_01007 5.23e-277 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 S-adenosylmethionine-dependent methyltransferase
HEGIFEPM_01008 2.51e-200 glcU - - U ko:K05340 - ko00000,ko02000 sugar transport
HEGIFEPM_01009 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
HEGIFEPM_01010 2.1e-33 - - - - - - - -
HEGIFEPM_01011 3.13e-15 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HEGIFEPM_01012 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HEGIFEPM_01013 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HEGIFEPM_01014 0.0 - 3.6.3.44 - P ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter transmembrane region
HEGIFEPM_01015 4.63e-24 - - - - - - - -
HEGIFEPM_01016 2.16e-26 - - - - - - - -
HEGIFEPM_01017 9.35e-24 - - - - - - - -
HEGIFEPM_01018 9.35e-24 - - - - - - - -
HEGIFEPM_01019 9.35e-24 - - - - - - - -
HEGIFEPM_01020 1.07e-26 - - - - - - - -
HEGIFEPM_01021 1.56e-22 - - - - - - - -
HEGIFEPM_01022 3.26e-24 - - - - - - - -
HEGIFEPM_01023 6.58e-24 - - - - - - - -
HEGIFEPM_01024 0.0 inlJ - - M - - - MucBP domain
HEGIFEPM_01025 0.0 - - - D - - - nuclear chromosome segregation
HEGIFEPM_01026 1.56e-50 - - - K - - - MarR family
HEGIFEPM_01027 0.0 - - - L ko:K07487 - ko00000 Transposase
HEGIFEPM_01028 9.28e-58 - - - - - - - -
HEGIFEPM_01029 1.28e-51 - - - - - - - -
HEGIFEPM_01031 1.98e-40 - - - - - - - -
HEGIFEPM_01033 3.82e-278 int3 - - L - - - Belongs to the 'phage' integrase family
HEGIFEPM_01035 2.07e-43 - - - - - - - -
HEGIFEPM_01039 1.52e-16 - - - M - - - LysM domain
HEGIFEPM_01042 1.91e-17 - - - S ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
HEGIFEPM_01043 8.96e-68 - - - - - - - -
HEGIFEPM_01044 4.17e-60 - - - S - - - Domain of unknown function (DUF5067)
HEGIFEPM_01045 2.64e-202 - - - J - - - Domain of unknown function (DUF4041)
HEGIFEPM_01046 6.69e-98 - - - E - - - IrrE N-terminal-like domain
HEGIFEPM_01047 1.32e-80 - - - K - - - Helix-turn-helix domain
HEGIFEPM_01048 6.7e-36 - - - K - - - Helix-turn-helix
HEGIFEPM_01050 5.68e-40 - - - K - - - Cro/C1-type HTH DNA-binding domain
HEGIFEPM_01051 4.61e-36 - - - K - - - Cro/C1-type HTH DNA-binding domain
HEGIFEPM_01053 6.59e-72 - - - - - - - -
HEGIFEPM_01054 7.73e-104 - - - - - - - -
HEGIFEPM_01055 5.03e-91 - - - - - - - -
HEGIFEPM_01056 5.03e-197 - - - L ko:K07455 - ko00000,ko03400 RecT family
HEGIFEPM_01057 5.04e-166 pi112 - - L - - - PDDEXK-like domain of unknown function (DUF3799)
HEGIFEPM_01058 7.92e-147 - - - L - - - DnaD domain protein
HEGIFEPM_01059 1.35e-42 - - - L - - - DnaD domain protein
HEGIFEPM_01060 1.27e-64 - - - - - - - -
HEGIFEPM_01061 1.23e-71 - - - - - - - -
HEGIFEPM_01062 1.29e-83 - - - L - - - Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HEGIFEPM_01063 5.95e-06 - - - - - - - -
HEGIFEPM_01065 6.18e-18 - - - - - - - -
HEGIFEPM_01067 3.86e-107 - - - S - - - Phage transcriptional regulator, ArpU family
HEGIFEPM_01070 1.94e-17 - - - - - - - -
HEGIFEPM_01071 5.06e-84 - - - L ko:K07474 - ko00000 Terminase small subunit
HEGIFEPM_01072 1.78e-305 - - - S - - - Terminase-like family
HEGIFEPM_01073 0.0 - - - S - - - Phage portal protein, SPP1 Gp6-like
HEGIFEPM_01074 4.98e-51 - - - J ko:K07584 - ko00000 Cysteine protease Prp
HEGIFEPM_01075 0.0 - - - S - - - Phage Mu protein F like protein
HEGIFEPM_01076 3.05e-41 - - - - - - - -
HEGIFEPM_01079 1.16e-63 - - - - - - - -
HEGIFEPM_01080 2.08e-222 - - - S - - - Phage major capsid protein E
HEGIFEPM_01082 2.9e-68 - - - - - - - -
HEGIFEPM_01083 9.63e-68 - - - - - - - -
HEGIFEPM_01084 5.34e-115 - - - - - - - -
HEGIFEPM_01085 3.49e-72 - - - - - - - -
HEGIFEPM_01086 7.42e-102 - - - S - - - Phage tail tube protein, TTP
HEGIFEPM_01087 1.42e-83 - - - - - - - -
HEGIFEPM_01088 3.76e-32 - - - - - - - -
HEGIFEPM_01089 0.0 - - - D - - - domain protein
HEGIFEPM_01090 2.29e-81 - - - - - - - -
HEGIFEPM_01091 0.0 - - - LM - - - DNA recombination
HEGIFEPM_01092 5.63e-33 - - - S - - - Protein of unknown function (DUF1617)
HEGIFEPM_01093 6.76e-35 - - - S - - - Protein of unknown function (DUF1617)
HEGIFEPM_01095 7.37e-231 lysA2 - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
HEGIFEPM_01096 9.2e-64 - - - - - - - -
HEGIFEPM_01097 5.28e-58 - - - S - - - Bacteriophage holin
HEGIFEPM_01099 2.96e-182 icaB - - G - - - Polysaccharide deacetylase
HEGIFEPM_01100 1.81e-85 yxeA - - S - - - Protein of unknown function (DUF1093)
HEGIFEPM_01101 0.0 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
HEGIFEPM_01102 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
HEGIFEPM_01103 5.37e-182 - - - - - - - -
HEGIFEPM_01104 1.33e-77 - - - - - - - -
HEGIFEPM_01105 1.9e-260 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
HEGIFEPM_01106 2.1e-41 - - - - - - - -
HEGIFEPM_01107 4.39e-244 ampC - - V - - - Beta-lactamase
HEGIFEPM_01108 4.95e-250 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
HEGIFEPM_01109 1.83e-175 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
HEGIFEPM_01110 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
HEGIFEPM_01111 5e-141 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
HEGIFEPM_01112 1.88e-251 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HEGIFEPM_01113 5.96e-205 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HEGIFEPM_01114 1.79e-243 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HEGIFEPM_01115 3.04e-297 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HEGIFEPM_01116 7.81e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HEGIFEPM_01117 1.44e-293 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
HEGIFEPM_01118 4.82e-165 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
HEGIFEPM_01119 1.81e-37 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HEGIFEPM_01120 5.41e-77 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HEGIFEPM_01121 2.03e-118 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HEGIFEPM_01122 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HEGIFEPM_01123 1.3e-212 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HEGIFEPM_01124 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HEGIFEPM_01125 5.95e-74 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
HEGIFEPM_01126 2.94e-315 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HEGIFEPM_01127 1.68e-132 - - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HEGIFEPM_01128 1.44e-230 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
HEGIFEPM_01129 1.52e-57 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
HEGIFEPM_01130 2.54e-46 - - - S - - - Protein of unknown function (DUF2969)
HEGIFEPM_01131 2.15e-280 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
HEGIFEPM_01132 3.2e-64 gcsH2 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 glycine cleavage
HEGIFEPM_01133 2.24e-239 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HEGIFEPM_01134 2.1e-151 metI - - U ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HEGIFEPM_01135 1.7e-164 metQ - - M ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
HEGIFEPM_01136 3.34e-215 hicD3 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
HEGIFEPM_01137 1.88e-226 - - - S - - - Protein of unknown function (DUF2785)
HEGIFEPM_01138 7.55e-242 - 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HEGIFEPM_01139 6.54e-273 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
HEGIFEPM_01140 6.45e-111 glpQ3 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
HEGIFEPM_01141 4.7e-240 glpQ3 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
HEGIFEPM_01142 3.41e-16 - - - K - - - Helix-turn-helix XRE-family like proteins
HEGIFEPM_01143 1.19e-175 - - - K - - - Helix-turn-helix XRE-family like proteins
HEGIFEPM_01144 1.91e-259 bla2 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
HEGIFEPM_01145 2.37e-107 uspA - - T - - - universal stress protein
HEGIFEPM_01146 1.34e-52 - - - - - - - -
HEGIFEPM_01147 2.96e-302 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
HEGIFEPM_01148 0.0 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
HEGIFEPM_01149 1.31e-119 - - - K - - - Periplasmic binding proteins and sugar binding domain of LacI family
HEGIFEPM_01150 3.79e-85 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
HEGIFEPM_01151 4.54e-132 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
HEGIFEPM_01152 5.82e-139 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose fructose sorbose family IID component
HEGIFEPM_01153 3.43e-55 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
HEGIFEPM_01154 7.24e-291 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
HEGIFEPM_01155 3.74e-58 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HEGIFEPM_01156 6.4e-142 - - - S - - - Protein of unknown function (DUF1648)
HEGIFEPM_01157 2.82e-105 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
HEGIFEPM_01158 4.02e-145 yktB - - S - - - Belongs to the UPF0637 family
HEGIFEPM_01159 2.15e-137 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HEGIFEPM_01160 1.07e-104 yebR 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
HEGIFEPM_01161 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HEGIFEPM_01163 7.42e-277 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
HEGIFEPM_01164 7.66e-292 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HEGIFEPM_01165 3.3e-301 gshF 6.3.2.2 - H ko:K01919,ko:K16786,ko:K16787 ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the glutamate--cysteine ligase type 1 family
HEGIFEPM_01166 3.56e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HEGIFEPM_01167 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HEGIFEPM_01168 9.36e-317 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
HEGIFEPM_01169 1.15e-150 radC - - L ko:K03630 - ko00000 DNA repair protein
HEGIFEPM_01170 1.74e-211 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
HEGIFEPM_01171 3.76e-184 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
HEGIFEPM_01172 9.47e-115 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
HEGIFEPM_01173 3.81e-150 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HEGIFEPM_01174 1.23e-187 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
HEGIFEPM_01175 1.09e-140 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
HEGIFEPM_01176 3.17e-149 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HEGIFEPM_01177 1.51e-198 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
HEGIFEPM_01178 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HEGIFEPM_01179 2.33e-84 ymfF - - S - - - Peptidase M16 inactive domain protein
HEGIFEPM_01180 1.09e-197 ymfF - - S - - - Peptidase M16 inactive domain protein
HEGIFEPM_01181 0.0 ymfH - - S - - - Peptidase M16
HEGIFEPM_01182 5.74e-172 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
HEGIFEPM_01183 1.92e-127 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HEGIFEPM_01184 2.7e-295 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
HEGIFEPM_01185 2.43e-264 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HEGIFEPM_01186 6.57e-291 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
HEGIFEPM_01187 6.18e-197 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 YmdB-like protein
HEGIFEPM_01188 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HEGIFEPM_01189 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HEGIFEPM_01190 1.35e-93 - - - - - - - -
HEGIFEPM_01191 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
HEGIFEPM_01192 4.02e-114 - - - - - - - -
HEGIFEPM_01193 2.83e-138 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HEGIFEPM_01194 2.62e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HEGIFEPM_01195 5.87e-256 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HEGIFEPM_01196 9.91e-289 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HEGIFEPM_01197 1.32e-63 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
HEGIFEPM_01198 2.48e-276 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HEGIFEPM_01199 8.32e-227 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
HEGIFEPM_01200 2.79e-316 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HEGIFEPM_01201 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HEGIFEPM_01202 5e-57 yrzL - - S - - - Belongs to the UPF0297 family
HEGIFEPM_01203 5.39e-96 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HEGIFEPM_01204 1.31e-63 yrzB - - S - - - Belongs to the UPF0473 family
HEGIFEPM_01205 1.06e-49 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HEGIFEPM_01206 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HEGIFEPM_01207 3e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
HEGIFEPM_01208 1.45e-161 yslB - - S - - - Protein of unknown function (DUF2507)
HEGIFEPM_01209 5.06e-194 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
HEGIFEPM_01210 8.49e-144 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HEGIFEPM_01211 4.03e-125 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
HEGIFEPM_01212 7.94e-114 ykuL - - S - - - (CBS) domain
HEGIFEPM_01213 2.29e-112 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HEGIFEPM_01214 7.85e-288 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HEGIFEPM_01215 2.31e-202 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
HEGIFEPM_01216 1.88e-75 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HEGIFEPM_01217 1.6e-96 - - - - - - - -
HEGIFEPM_01218 1.29e-105 - - - K - - - helix_turn_helix, mercury resistance
HEGIFEPM_01219 5.18e-274 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
HEGIFEPM_01220 5.44e-232 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
HEGIFEPM_01221 4.56e-210 - - - G - - - Xylose isomerase domain protein TIM barrel
HEGIFEPM_01222 2.34e-63 - - - S ko:K09004 - ko00000 DsrE/DsrF-like family
HEGIFEPM_01223 2.21e-168 yebC - - K - - - Transcriptional regulatory protein
HEGIFEPM_01224 2.06e-205 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HEGIFEPM_01225 1.55e-225 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
HEGIFEPM_01226 5.94e-240 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
HEGIFEPM_01227 1.97e-72 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
HEGIFEPM_01228 4.29e-108 - - - NU ko:K02246 - ko00000,ko00002,ko02044 general secretion pathway protein
HEGIFEPM_01229 3.03e-27 - - - - ko:K02671 - ko00000,ko02035,ko02044 -
HEGIFEPM_01230 1.85e-112 - - - S - - - Prokaryotic N-terminal methylation motif
HEGIFEPM_01232 6.37e-236 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
HEGIFEPM_01233 4.7e-282 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HEGIFEPM_01234 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
HEGIFEPM_01235 5.77e-151 - - - S - - - Calcineurin-like phosphoesterase
HEGIFEPM_01236 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HEGIFEPM_01237 6.53e-115 yutD - - S - - - Protein of unknown function (DUF1027)
HEGIFEPM_01238 7.18e-189 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HEGIFEPM_01239 5.39e-74 - - - S - - - Protein of unknown function (DUF1461)
HEGIFEPM_01240 8.65e-41 - - - S - - - Protein of unknown function (DUF1461)
HEGIFEPM_01241 7.18e-153 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
HEGIFEPM_01242 5.16e-141 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HEGIFEPM_01243 2e-98 yugI - - J ko:K07570,ko:K07571 - ko00000 general stress protein
HEGIFEPM_01244 1.11e-84 - - - - - - - -
HEGIFEPM_01245 1.35e-55 - - - S - - - COG NOG38524 non supervised orthologous group
HEGIFEPM_01267 1.08e-117 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
HEGIFEPM_01268 3.28e-177 yhfI - - S - - - Metallo-beta-lactamase superfamily
HEGIFEPM_01269 9.28e-89 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HEGIFEPM_01270 7.12e-170 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HEGIFEPM_01271 2.34e-266 coiA - - S ko:K06198 - ko00000 Competence protein
HEGIFEPM_01272 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
HEGIFEPM_01273 2.24e-148 yjbH - - Q - - - Thioredoxin
HEGIFEPM_01274 2.6e-156 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
HEGIFEPM_01275 1.29e-193 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HEGIFEPM_01276 1.09e-222 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HEGIFEPM_01277 7.21e-150 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
HEGIFEPM_01278 1.6e-246 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
HEGIFEPM_01279 2.68e-75 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
HEGIFEPM_01280 9.52e-264 XK27_05220 - - S - - - AI-2E family transporter
HEGIFEPM_01281 4.82e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HEGIFEPM_01282 1.62e-71 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
HEGIFEPM_01283 8.93e-120 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
HEGIFEPM_01285 6.93e-299 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HEGIFEPM_01286 2.5e-147 - - - S ko:K07118 - ko00000 NAD(P)H-binding
HEGIFEPM_01287 4.97e-124 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HEGIFEPM_01288 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
HEGIFEPM_01289 4.99e-224 - - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
HEGIFEPM_01290 3.22e-82 - - - S - - - Protein of unknown function (DUF3397)
HEGIFEPM_01291 1.35e-100 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
HEGIFEPM_01292 2.12e-225 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HEGIFEPM_01293 7.01e-76 ftsL - - D - - - Cell division protein FtsL
HEGIFEPM_01294 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HEGIFEPM_01295 2.81e-231 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HEGIFEPM_01296 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HEGIFEPM_01297 6.49e-130 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HEGIFEPM_01298 4.99e-79 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HEGIFEPM_01299 2.34e-208 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HEGIFEPM_01300 3.55e-312 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HEGIFEPM_01301 9.39e-295 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HEGIFEPM_01302 1.56e-93 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HEGIFEPM_01303 6.45e-49 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
HEGIFEPM_01304 2.06e-187 ylmH - - S - - - S4 domain protein
HEGIFEPM_01305 6.52e-124 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
HEGIFEPM_01306 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HEGIFEPM_01307 4.22e-243 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HEGIFEPM_01308 8.62e-126 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
HEGIFEPM_01309 7.74e-47 - - - - - - - -
HEGIFEPM_01310 2.04e-158 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HEGIFEPM_01311 6.38e-279 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
HEGIFEPM_01312 4.94e-75 XK27_04120 - - S - - - Putative amino acid metabolism
HEGIFEPM_01313 6.7e-285 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HEGIFEPM_01314 9.64e-307 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
HEGIFEPM_01315 4.64e-150 ktrA - - P ko:K03499 - ko00000,ko02000 domain protein
HEGIFEPM_01316 4.17e-153 - - - N - - - WxL domain surface cell wall-binding
HEGIFEPM_01317 1.22e-248 - - - S - - - Bacterial protein of unknown function (DUF916)
HEGIFEPM_01318 0.0 - - - N - - - domain, Protein
HEGIFEPM_01319 2.41e-157 pgm6 - - G - - - phosphoglycerate mutase
HEGIFEPM_01320 1.02e-155 - - - S - - - repeat protein
HEGIFEPM_01321 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HEGIFEPM_01322 7.6e-220 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HEGIFEPM_01323 3.15e-159 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
HEGIFEPM_01324 3.76e-206 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HEGIFEPM_01325 6.21e-39 - - - - - - - -
HEGIFEPM_01326 2.43e-240 ytlR - - I - - - Diacylglycerol kinase catalytic domain
HEGIFEPM_01327 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HEGIFEPM_01328 4.86e-45 ykzG - - S - - - Belongs to the UPF0356 family
HEGIFEPM_01329 6.45e-111 - - - - - - - -
HEGIFEPM_01330 3.95e-132 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HEGIFEPM_01331 1.21e-268 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
HEGIFEPM_01332 6.35e-230 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
HEGIFEPM_01333 2.36e-285 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HEGIFEPM_01334 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
HEGIFEPM_01335 2.15e-209 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 L-malate dehydrogenase activity
HEGIFEPM_01336 2.64e-62 yktA - - S - - - Belongs to the UPF0223 family
HEGIFEPM_01337 1.23e-177 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
HEGIFEPM_01338 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
HEGIFEPM_01339 1.1e-257 - - - - - - - -
HEGIFEPM_01340 1.92e-134 - - - - - - - -
HEGIFEPM_01341 0.0 icaA - - M - - - Glycosyl transferase family group 2
HEGIFEPM_01342 0.0 - - - - - - - -
HEGIFEPM_01343 2.51e-261 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
HEGIFEPM_01344 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HEGIFEPM_01345 1.91e-66 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
HEGIFEPM_01346 4.98e-131 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
HEGIFEPM_01347 2.99e-109 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HEGIFEPM_01348 1.05e-251 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
HEGIFEPM_01349 3.52e-90 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
HEGIFEPM_01350 7.1e-116 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
HEGIFEPM_01351 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
HEGIFEPM_01352 1.7e-239 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
HEGIFEPM_01353 1.18e-46 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
HEGIFEPM_01354 2.9e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HEGIFEPM_01355 2.22e-261 - - - EGP - - - Major Facilitator Superfamily
HEGIFEPM_01356 1.29e-200 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HEGIFEPM_01357 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HEGIFEPM_01358 3.4e-203 - - - S - - - Tetratricopeptide repeat
HEGIFEPM_01359 4.38e-286 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HEGIFEPM_01360 6.48e-288 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HEGIFEPM_01361 7.8e-300 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HEGIFEPM_01362 9.6e-143 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
HEGIFEPM_01363 1.3e-65 - - - S - - - mazG nucleotide pyrophosphohydrolase
HEGIFEPM_01364 3.75e-94 - - - S - - - Iron-sulphur cluster biosynthesis
HEGIFEPM_01365 5.12e-31 - - - - - - - -
HEGIFEPM_01366 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
HEGIFEPM_01367 3.97e-173 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HEGIFEPM_01368 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HEGIFEPM_01369 8.45e-162 epsB - - M - - - biosynthesis protein
HEGIFEPM_01370 4.97e-157 ywqD - - D - - - Capsular exopolysaccharide family
HEGIFEPM_01371 5.54e-189 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
HEGIFEPM_01372 8.71e-231 cps4D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
HEGIFEPM_01373 1.91e-163 tuaA - - M - - - Bacterial sugar transferase
HEGIFEPM_01374 1.4e-259 cps4F - - M - - - Glycosyl transferases group 1
HEGIFEPM_01375 3.84e-235 cps4G - - M - - - Glycosyltransferase Family 4
HEGIFEPM_01376 5.23e-295 - - - - - - - -
HEGIFEPM_01377 2.05e-229 cps4I - - M - - - Glycosyltransferase like family 2
HEGIFEPM_01378 0.0 cps4J - - S - - - MatE
HEGIFEPM_01379 0.0 - 3.1.4.53 - S ko:K03651 ko00230,ko02025,map00230,map02025 ko00000,ko00001,ko01000 Calcineurin-like phosphoesterase
HEGIFEPM_01380 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
HEGIFEPM_01381 7.34e-219 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HEGIFEPM_01382 3.02e-175 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
HEGIFEPM_01383 8.98e-311 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HEGIFEPM_01384 6.62e-62 - - - - - - - -
HEGIFEPM_01385 8.34e-228 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HEGIFEPM_01386 7.09e-180 - - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
HEGIFEPM_01387 1.84e-67 - - - S - - - Lipopolysaccharide assembly protein A domain
HEGIFEPM_01388 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
HEGIFEPM_01389 1.52e-120 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HEGIFEPM_01390 7.9e-136 - - - K - - - Helix-turn-helix domain
HEGIFEPM_01391 2.87e-270 - - - EGP - - - Major facilitator Superfamily
HEGIFEPM_01392 2.84e-75 ybjQ - - S - - - Belongs to the UPF0145 family
HEGIFEPM_01393 2.81e-181 - - - Q - - - Methyltransferase
HEGIFEPM_01394 1.75e-43 - - - - - - - -
HEGIFEPM_01395 2.41e-05 - - - L ko:K07483 - ko00000 transposase activity
HEGIFEPM_01396 2.74e-43 - 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Hydrolase, nudix family
HEGIFEPM_01398 2.38e-294 rodA - - D ko:K05837 - ko00000,ko03036 Cell cycle protein
HEGIFEPM_01399 9.94e-296 - - - P ko:K02050 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HEGIFEPM_01400 1.1e-183 - - - P ko:K02049 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HEGIFEPM_01401 1.89e-282 ywtF_2 - - K - - - Cell envelope-related transcriptional attenuator domain
HEGIFEPM_01402 6.27e-131 - - - L - - - Helix-turn-helix domain
HEGIFEPM_01403 2.3e-226 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 Glycosyltransferase like family 2
HEGIFEPM_01405 3.81e-87 - - - - - - - -
HEGIFEPM_01406 1.01e-100 - - - - - - - -
HEGIFEPM_01407 1.1e-276 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
HEGIFEPM_01408 5.49e-123 - - - - - - - -
HEGIFEPM_01409 2.16e-55 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HEGIFEPM_01410 1.16e-28 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HEGIFEPM_01411 7.68e-48 ynzC - - S - - - UPF0291 protein
HEGIFEPM_01412 3.96e-44 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
HEGIFEPM_01413 1.46e-153 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
HEGIFEPM_01414 9.34e-175 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
HEGIFEPM_01415 4.67e-63 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
HEGIFEPM_01416 7.5e-237 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEGIFEPM_01417 7.68e-245 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HEGIFEPM_01418 2.92e-172 - - - S ko:K07025 - ko00000 Haloacid dehalogenase-like hydrolase
HEGIFEPM_01419 6.33e-185 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
HEGIFEPM_01420 1.88e-194 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HEGIFEPM_01421 3.01e-165 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
HEGIFEPM_01422 9.83e-113 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HEGIFEPM_01423 3.71e-189 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HEGIFEPM_01424 1.13e-175 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
HEGIFEPM_01425 4.64e-294 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
HEGIFEPM_01426 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HEGIFEPM_01427 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HEGIFEPM_01428 9.74e-108 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
HEGIFEPM_01429 4.46e-275 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
HEGIFEPM_01430 2.95e-65 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
HEGIFEPM_01431 3.28e-63 ylxQ - - J - - - ribosomal protein
HEGIFEPM_01432 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HEGIFEPM_01433 3.04e-71 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HEGIFEPM_01434 0.0 - - - G - - - Major Facilitator
HEGIFEPM_01435 3.67e-275 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HEGIFEPM_01436 1.63e-121 - - - - - - - -
HEGIFEPM_01437 4.53e-300 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HEGIFEPM_01438 2.44e-245 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
HEGIFEPM_01439 3.99e-112 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HEGIFEPM_01440 8.94e-221 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HEGIFEPM_01441 1.53e-241 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
HEGIFEPM_01442 1.19e-169 budA 4.1.1.5 - Q ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
HEGIFEPM_01443 4.42e-248 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HEGIFEPM_01444 4.52e-111 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HEGIFEPM_01445 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
HEGIFEPM_01446 2.54e-266 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HEGIFEPM_01447 4.21e-266 pbpX2 - - V - - - Beta-lactamase
HEGIFEPM_01448 8.59e-27 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
HEGIFEPM_01449 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEGIFEPM_01450 1.14e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
HEGIFEPM_01451 5.75e-47 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEGIFEPM_01452 1.68e-312 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HEGIFEPM_01453 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HEGIFEPM_01454 1.73e-67 - - - - - - - -
HEGIFEPM_01455 4.78e-65 - - - - - - - -
HEGIFEPM_01456 1.11e-147 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
HEGIFEPM_01457 2.04e-226 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
HEGIFEPM_01458 3.13e-172 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HEGIFEPM_01459 2.56e-76 - - - - - - - -
HEGIFEPM_01460 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HEGIFEPM_01461 4.75e-101 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HEGIFEPM_01462 1.35e-147 yjcF - - J - - - HAD-hyrolase-like
HEGIFEPM_01463 1.87e-213 - - - G - - - Fructosamine kinase
HEGIFEPM_01464 2.83e-200 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 N-acetylmuramoyl-L-alanine amidase
HEGIFEPM_01465 1.43e-309 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
HEGIFEPM_01466 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HEGIFEPM_01467 2.61e-132 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HEGIFEPM_01468 4.35e-204 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
HEGIFEPM_01469 1.92e-286 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HEGIFEPM_01470 7.36e-220 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HEGIFEPM_01471 2.72e-41 - - - C - - - Enoyl-(Acyl carrier protein) reductase
HEGIFEPM_01472 7.92e-101 - - - C - - - Enoyl-(Acyl carrier protein) reductase
HEGIFEPM_01473 2.32e-194 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HEGIFEPM_01474 1.09e-30 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
HEGIFEPM_01475 9.21e-94 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
HEGIFEPM_01476 4.81e-229 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
HEGIFEPM_01477 7.7e-110 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HEGIFEPM_01478 1.15e-94 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
HEGIFEPM_01479 7.92e-217 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HEGIFEPM_01480 2.84e-189 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
HEGIFEPM_01481 8.64e-224 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
HEGIFEPM_01482 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
HEGIFEPM_01483 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HEGIFEPM_01484 1.74e-251 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HEGIFEPM_01485 1.18e-85 ytrA - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
HEGIFEPM_01486 8.41e-51 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HEGIFEPM_01487 3.09e-142 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HEGIFEPM_01488 1.56e-257 - - - - - - - -
HEGIFEPM_01489 5.21e-254 - - - - - - - -
HEGIFEPM_01490 3.5e-169 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HEGIFEPM_01491 1.25e-207 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HEGIFEPM_01492 0.000138 yjdF - - S - - - Protein of unknown function (DUF2992)
HEGIFEPM_01493 1.28e-148 - - - S - - - Psort location CytoplasmicMembrane, score
HEGIFEPM_01494 5.9e-103 - - - K - - - MarR family
HEGIFEPM_01495 6.64e-109 - - - K ko:K03827 - ko00000,ko01000 Acetyltransferase (GNAT) domain
HEGIFEPM_01497 4.17e-204 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HEGIFEPM_01498 1.27e-174 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
HEGIFEPM_01499 1.03e-265 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HEGIFEPM_01500 2.72e-135 desR - - K ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, Lux Regulon
HEGIFEPM_01501 1.24e-297 nox4 - - C - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HEGIFEPM_01503 7.96e-223 cryZ 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
HEGIFEPM_01504 1.41e-207 - - - K - - - Transcriptional regulator
HEGIFEPM_01505 2.12e-102 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2255)
HEGIFEPM_01506 1.76e-146 - - - GM - - - NmrA-like family
HEGIFEPM_01507 3.2e-207 - - - S - - - Alpha beta hydrolase
HEGIFEPM_01508 2.49e-167 - - - K - - - Helix-turn-helix domain, rpiR family
HEGIFEPM_01509 2.31e-132 thgA3 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
HEGIFEPM_01510 7.51e-147 - 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 haloacid dehalogenase-like hydrolase
HEGIFEPM_01511 4.22e-35 pts14C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEGIFEPM_01512 8.13e-90 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HEGIFEPM_01513 2.15e-07 - - - K - - - transcriptional regulator
HEGIFEPM_01514 1.86e-272 - - - S - - - membrane
HEGIFEPM_01515 6.13e-105 - - - K - - - Bacterial regulatory proteins, tetR family
HEGIFEPM_01516 0.0 - - - S - - - Zinc finger, swim domain protein
HEGIFEPM_01517 8.09e-146 - - - GM - - - epimerase
HEGIFEPM_01518 6.34e-90 - - - S - - - Protein of unknown function (DUF1722)
HEGIFEPM_01519 2.65e-93 spx2 - - P ko:K16509 - ko00000 ArsC family
HEGIFEPM_01520 1.4e-137 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
HEGIFEPM_01521 1.68e-176 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
HEGIFEPM_01522 0.0 nox - - P - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HEGIFEPM_01523 2.25e-265 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
HEGIFEPM_01524 4.38e-102 - - - K - - - Transcriptional regulator
HEGIFEPM_01525 3.1e-305 - - - U ko:K18926 - ko00000,ko00002,ko02000 Major Facilitator Superfamily
HEGIFEPM_01526 8.96e-310 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HEGIFEPM_01527 0.0 - - - P - - - Cation transporter/ATPase, N-terminus
HEGIFEPM_01528 1.51e-232 - - - C - - - Zinc-binding dehydrogenase
HEGIFEPM_01529 4.28e-281 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
HEGIFEPM_01530 7.94e-237 - - - - - - - -
HEGIFEPM_01531 7.43e-119 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
HEGIFEPM_01532 1.94e-83 - - - P - - - Rhodanese Homology Domain
HEGIFEPM_01533 0.0 pps 2.7.9.2 - H ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HEGIFEPM_01534 2.74e-112 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HEGIFEPM_01535 3.85e-209 drrA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HEGIFEPM_01536 8.81e-166 drrB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
HEGIFEPM_01537 1.37e-292 - - - M - - - O-Antigen ligase
HEGIFEPM_01538 8.34e-165 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
HEGIFEPM_01539 3.25e-251 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HEGIFEPM_01540 3.17e-299 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
HEGIFEPM_01541 0.0 clpB - - O ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HEGIFEPM_01542 7.03e-40 - - - S - - - Protein of unknown function (DUF2929)
HEGIFEPM_01543 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
HEGIFEPM_01544 8.69e-230 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HEGIFEPM_01545 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
HEGIFEPM_01546 2.51e-98 ytwI - - S - - - Protein of unknown function (DUF441)
HEGIFEPM_01547 7.94e-218 yitL - - S ko:K00243 - ko00000 S1 domain
HEGIFEPM_01548 3.13e-211 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
HEGIFEPM_01549 3.99e-92 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEGIFEPM_01550 7.1e-176 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HEGIFEPM_01551 1.3e-132 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HEGIFEPM_01552 2.69e-167 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HEGIFEPM_01553 2.24e-126 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HEGIFEPM_01554 5.38e-249 - - - S - - - Helix-turn-helix domain
HEGIFEPM_01555 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
HEGIFEPM_01556 1.25e-39 - - - M - - - Lysin motif
HEGIFEPM_01557 1.27e-151 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
HEGIFEPM_01558 1.98e-281 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
HEGIFEPM_01559 2.06e-314 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
HEGIFEPM_01560 5.57e-55 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HEGIFEPM_01561 7.1e-292 XK27_05225 - - S - - - Tetratricopeptide repeat protein
HEGIFEPM_01562 1.29e-192 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
HEGIFEPM_01563 5.66e-185 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HEGIFEPM_01564 8.58e-290 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HEGIFEPM_01565 6.46e-109 - - - - - - - -
HEGIFEPM_01566 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
HEGIFEPM_01567 4.04e-242 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HEGIFEPM_01568 1.8e-119 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HEGIFEPM_01569 2.03e-189 WQ51_01275 - - S - - - EDD domain protein, DegV family
HEGIFEPM_01570 1.02e-209 XK27_03630 - - E - - - GDSL-like Lipase/Acylhydrolase
HEGIFEPM_01571 3.29e-147 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
HEGIFEPM_01572 9.33e-48 yozE - - S - - - Belongs to the UPF0346 family
HEGIFEPM_01573 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
HEGIFEPM_01574 0.0 qacA - - EGP - - - Major Facilitator
HEGIFEPM_01575 2.48e-252 XK27_00915 - - C - - - Luciferase-like monooxygenase
HEGIFEPM_01576 1.23e-160 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
HEGIFEPM_01577 1.22e-219 cpsY - - K - - - Transcriptional regulator, LysR family
HEGIFEPM_01578 5.13e-292 XK27_05470 - - E - - - Methionine synthase
HEGIFEPM_01580 2.25e-207 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HEGIFEPM_01581 5e-176 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HEGIFEPM_01582 8.11e-203 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
HEGIFEPM_01583 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HEGIFEPM_01584 0.0 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HEGIFEPM_01585 1.5e-227 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
HEGIFEPM_01586 6.84e-121 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HEGIFEPM_01587 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HEGIFEPM_01588 2.1e-216 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
HEGIFEPM_01589 2.4e-137 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HEGIFEPM_01590 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HEGIFEPM_01591 1.28e-191 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HEGIFEPM_01592 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HEGIFEPM_01593 3.82e-228 - - - K - - - Transcriptional regulator
HEGIFEPM_01594 3.91e-216 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
HEGIFEPM_01595 3.8e-105 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
HEGIFEPM_01596 9.17e-126 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HEGIFEPM_01597 1.07e-43 - - - S - - - YozE SAM-like fold
HEGIFEPM_01598 6.94e-202 - - - L - - - Phage integrase, N-terminal SAM-like domain
HEGIFEPM_01599 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HEGIFEPM_01600 1.06e-313 - - - M - - - Glycosyl transferase family group 2
HEGIFEPM_01601 1.98e-66 - - - - - - - -
HEGIFEPM_01602 1.86e-303 gshR1 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
HEGIFEPM_01603 1.6e-93 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HEGIFEPM_01604 1.34e-120 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
HEGIFEPM_01605 0.0 tarL 2.7.8.14, 2.7.8.47 - H ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HEGIFEPM_01606 3.5e-251 tarK 2.7.8.14, 2.7.8.46, 2.7.8.47 - H ko:K18704,ko:K21592 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HEGIFEPM_01607 3.61e-244 tarJ 1.1.1.137, 1.1.1.405 - E ko:K05352,ko:K21680 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
HEGIFEPM_01608 7.15e-165 tarI 2.7.7.40, 2.7.7.60 - I ko:K00991,ko:K21030 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
HEGIFEPM_01609 6.75e-290 - - - - - - - -
HEGIFEPM_01610 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
HEGIFEPM_01611 7.79e-78 - - - - - - - -
HEGIFEPM_01612 1.07e-173 - - - - - - - -
HEGIFEPM_01613 1.23e-311 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
HEGIFEPM_01614 2.59e-177 XK27_00890 - - S ko:K08974 - ko00000 Domain of unknown function (DUF368)
HEGIFEPM_01615 9.3e-167 yejC - - S - - - Protein of unknown function (DUF1003)
HEGIFEPM_01616 5.42e-67 XK27_08430 - - S - - - Staphylococcal protein of unknown function (DUF960)
HEGIFEPM_01618 4.93e-267 pmrB - - EGP - - - Major Facilitator Superfamily
HEGIFEPM_01619 2.32e-189 - - - C - - - Domain of unknown function (DUF4931)
HEGIFEPM_01620 1.23e-63 - - - - - - - -
HEGIFEPM_01621 2.38e-39 - - - - - - - -
HEGIFEPM_01622 2.9e-170 - - - S - - - Protein of unknown function (DUF975)
HEGIFEPM_01623 2.47e-101 yjcF 3.5.4.33, 4.4.1.8 - K ko:K02348,ko:K11991,ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007,ko03016 protein acetylation
HEGIFEPM_01624 9.14e-205 - - - S - - - EDD domain protein, DegV family
HEGIFEPM_01625 1.97e-87 - - - K - - - Transcriptional regulator
HEGIFEPM_01626 0.0 FbpA - - K - - - Fibronectin-binding protein
HEGIFEPM_01627 9.28e-171 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HEGIFEPM_01628 5.3e-209 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HEGIFEPM_01629 5.37e-117 - - - F - - - NUDIX domain
HEGIFEPM_01631 2.31e-174 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2087)
HEGIFEPM_01632 8.49e-92 - - - S - - - LuxR family transcriptional regulator
HEGIFEPM_01633 1.62e-86 cat 2.3.1.28 - V ko:K19271 - br01600,ko00000,ko01000,ko01504 Chloramphenicol acetyltransferase
HEGIFEPM_01634 3.51e-59 cat 2.3.1.28 - V ko:K19271 - br01600,ko00000,ko01000,ko01504 Chloramphenicol acetyltransferase
HEGIFEPM_01636 6.38e-92 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
HEGIFEPM_01637 2.01e-145 - - - G - - - Phosphoglycerate mutase family
HEGIFEPM_01638 0.0 - - - S - - - Bacterial membrane protein, YfhO
HEGIFEPM_01639 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
HEGIFEPM_01640 4.89e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
HEGIFEPM_01641 1.9e-115 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HEGIFEPM_01642 9.72e-225 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HEGIFEPM_01643 1.65e-97 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HEGIFEPM_01644 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
HEGIFEPM_01645 5.04e-82 esbA - - S - - - Family of unknown function (DUF5322)
HEGIFEPM_01646 3.28e-87 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
HEGIFEPM_01647 1.47e-268 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 FAD dependent oxidoreductase
HEGIFEPM_01648 3.69e-187 - - - S - - - hydrolase activity, acting on ester bonds
HEGIFEPM_01649 6.79e-249 - - - - - - - -
HEGIFEPM_01650 3.99e-158 - - - P ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HEGIFEPM_01651 1.71e-160 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
HEGIFEPM_01652 1.68e-233 - - - V - - - LD-carboxypeptidase
HEGIFEPM_01653 3.03e-312 - - - M ko:K07273 - ko00000 hydrolase, family 25
HEGIFEPM_01654 1.66e-101 - - - K - - - Acetyltransferase (GNAT) domain
HEGIFEPM_01655 9.93e-267 mccF - - V - - - LD-carboxypeptidase
HEGIFEPM_01656 5.54e-255 - - - M - - - Glycosyltransferase, group 2 family protein
HEGIFEPM_01657 7.86e-96 - - - S - - - SnoaL-like domain
HEGIFEPM_01658 4.17e-186 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
HEGIFEPM_01659 7.09e-187 - - - P - - - Major Facilitator Superfamily
HEGIFEPM_01660 3.26e-103 - - - P - - - Major Facilitator Superfamily
HEGIFEPM_01661 1.26e-61 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HEGIFEPM_01662 1.44e-282 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
HEGIFEPM_01664 9.98e-75 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HEGIFEPM_01665 2.12e-142 ypsA - - S - - - Belongs to the UPF0398 family
HEGIFEPM_01666 3.6e-152 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HEGIFEPM_01667 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
HEGIFEPM_01668 8.37e-231 phnT 3.6.3.30 - P ko:K02010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
HEGIFEPM_01669 4.86e-235 ftpB - - P ko:K02012 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HEGIFEPM_01670 0.0 ftpA - - P ko:K02011 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HEGIFEPM_01671 7.56e-109 - - - T - - - Universal stress protein family
HEGIFEPM_01672 3.19e-203 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
HEGIFEPM_01673 1.41e-141 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HEGIFEPM_01674 2.32e-238 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HEGIFEPM_01675 1.13e-165 dnaD - - L ko:K02086 - ko00000 Replication initiation and membrane attachment
HEGIFEPM_01676 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
HEGIFEPM_01677 3.1e-289 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
HEGIFEPM_01678 2.53e-107 ypmB - - S - - - protein conserved in bacteria
HEGIFEPM_01679 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
HEGIFEPM_01680 2.98e-217 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
HEGIFEPM_01681 1.1e-230 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
HEGIFEPM_01682 1.2e-260 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
HEGIFEPM_01683 4.98e-250 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HEGIFEPM_01684 3.36e-247 galM2 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
HEGIFEPM_01685 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
HEGIFEPM_01686 0.0 malT - - G ko:K16211 - ko00000,ko02000 Major Facilitator
HEGIFEPM_01688 4.17e-151 - - - S - - - Domain of unknown function (DUF4767)
HEGIFEPM_01689 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
HEGIFEPM_01690 3.86e-192 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
HEGIFEPM_01691 0.0 - - - E ko:K03294 - ko00000 Amino Acid
HEGIFEPM_01692 0.0 gabT 2.6.1.19, 5.1.1.21 - E ko:K00823,ko:K20708 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HEGIFEPM_01693 3.23e-58 - - - - - - - -
HEGIFEPM_01694 1.25e-66 - - - - - - - -
HEGIFEPM_01695 5.03e-182 - - - U ko:K10716 - ko00000,ko02000 Ion channel
HEGIFEPM_01696 1.04e-218 - 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 UbiA prenyltransferase family
HEGIFEPM_01697 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HEGIFEPM_01698 4.87e-37 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
HEGIFEPM_01699 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HEGIFEPM_01700 1.06e-53 - - - - - - - -
HEGIFEPM_01701 4e-40 - - - S - - - CsbD-like
HEGIFEPM_01702 1.29e-54 - - - S - - - transglycosylase associated protein
HEGIFEPM_01703 5.79e-21 - - - - - - - -
HEGIFEPM_01704 1.51e-48 - - - - - - - -
HEGIFEPM_01705 7.27e-211 - - - I - - - Diacylglycerol kinase catalytic domain
HEGIFEPM_01706 3.92e-87 - - - S - - - Protein of unknown function (DUF805)
HEGIFEPM_01707 5.28e-100 - - - T - - - Belongs to the universal stress protein A family
HEGIFEPM_01708 6.05e-108 tspO - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 TspO/MBR family
HEGIFEPM_01709 2.05e-55 - - - - - - - -
HEGIFEPM_01710 6.15e-62 ycnE - - S - - - Antibiotic biosynthesis monooxygenase
HEGIFEPM_01711 9.96e-147 - 1.14.99.53 AA10 S ko:K21713 - ko00000,ko01000 Lytic polysaccharide mono-oxygenase, cellulose-degrading
HEGIFEPM_01712 1.69e-276 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
HEGIFEPM_01713 2.02e-39 - - - - - - - -
HEGIFEPM_01714 1.48e-71 - - - - - - - -
HEGIFEPM_01715 1.14e-193 - - - O - - - Band 7 protein
HEGIFEPM_01716 0.0 - - - EGP - - - Major Facilitator
HEGIFEPM_01717 8.6e-121 - - - K - - - transcriptional regulator
HEGIFEPM_01718 2.66e-247 rsgA_2 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HEGIFEPM_01719 4.94e-114 ykhA - - I - - - Thioesterase superfamily
HEGIFEPM_01720 4.35e-206 - - - K - - - LysR substrate binding domain
HEGIFEPM_01721 3.64e-162 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
HEGIFEPM_01722 1.75e-129 - - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
HEGIFEPM_01723 2.29e-175 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
HEGIFEPM_01724 4.82e-179 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
HEGIFEPM_01725 6.43e-203 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HEGIFEPM_01726 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
HEGIFEPM_01727 1.71e-91 fabZ2 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
HEGIFEPM_01728 2.14e-95 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HEGIFEPM_01729 1.54e-289 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HEGIFEPM_01730 1.26e-162 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
HEGIFEPM_01731 4.05e-214 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
HEGIFEPM_01732 1.06e-48 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
HEGIFEPM_01733 2.3e-229 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HEGIFEPM_01734 8.55e-99 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HEGIFEPM_01735 8.02e-230 yneE - - K - - - Transcriptional regulator
HEGIFEPM_01736 3.39e-186 yneD - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HEGIFEPM_01737 3.12e-79 - - - S - - - Protein of unknown function (DUF1648)
HEGIFEPM_01738 2.3e-253 adhB 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
HEGIFEPM_01739 2.78e-273 hipO1 - - E ko:K21613 - ko00000,ko01000,ko01002 Peptidase family M20/M25/M40
HEGIFEPM_01740 1.98e-152 - - - E - - - glutamate:sodium symporter activity
HEGIFEPM_01741 4.58e-73 - - - E - - - glutamate:sodium symporter activity
HEGIFEPM_01742 1.95e-88 ybbJ - - K - - - Acetyltransferase (GNAT) family
HEGIFEPM_01743 5.45e-231 - 1.6.5.5 - C ko:K00344 - ko00000,ko01000 Zinc-binding dehydrogenase
HEGIFEPM_01744 1.02e-126 entB - - Q - - - Isochorismatase family
HEGIFEPM_01745 4.82e-183 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HEGIFEPM_01746 4.21e-286 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HEGIFEPM_01747 1.24e-139 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
HEGIFEPM_01748 1.28e-160 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
HEGIFEPM_01749 2.86e-224 trpD 2.4.2.18, 4.1.3.27 - F ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HEGIFEPM_01750 8.08e-135 trpG 4.1.3.27 - EH ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Peptidase C26
HEGIFEPM_01751 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Anthranilate synthase component I, N terminal region
HEGIFEPM_01753 0.0 XK27_00765 - - - ko:K01992 - ko00000,ko00002,ko02000 -
HEGIFEPM_01754 2.05e-179 ecsA_2 - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
HEGIFEPM_01755 9.06e-112 - - - - - - - -
HEGIFEPM_01756 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
HEGIFEPM_01757 1.03e-66 - - - - - - - -
HEGIFEPM_01758 3.15e-78 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HEGIFEPM_01759 1.57e-179 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
HEGIFEPM_01760 2.24e-123 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HEGIFEPM_01761 9.99e-53 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
HEGIFEPM_01762 1.6e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
HEGIFEPM_01763 7.69e-300 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HEGIFEPM_01764 1.46e-77 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HEGIFEPM_01765 2.85e-293 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HEGIFEPM_01766 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
HEGIFEPM_01767 4.49e-167 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HEGIFEPM_01768 3.33e-47 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
HEGIFEPM_01769 2.17e-244 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HEGIFEPM_01770 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HEGIFEPM_01771 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
HEGIFEPM_01772 7.09e-76 yloU - - S - - - Asp23 family, cell envelope-related function
HEGIFEPM_01773 1.61e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
HEGIFEPM_01774 3.05e-159 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
HEGIFEPM_01775 2.22e-151 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
HEGIFEPM_01776 4.91e-209 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HEGIFEPM_01777 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
HEGIFEPM_01778 1.62e-173 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
HEGIFEPM_01779 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HEGIFEPM_01780 1.49e-224 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HEGIFEPM_01781 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HEGIFEPM_01782 2.05e-277 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HEGIFEPM_01783 3.93e-41 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HEGIFEPM_01784 6.96e-145 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
HEGIFEPM_01785 8.28e-73 - - - - - - - -
HEGIFEPM_01786 1.36e-136 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HEGIFEPM_01787 3.8e-224 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HEGIFEPM_01788 7.11e-135 opuCB - - E ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HEGIFEPM_01789 4.51e-284 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HEGIFEPM_01790 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
HEGIFEPM_01791 5.28e-100 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
HEGIFEPM_01792 4.49e-192 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
HEGIFEPM_01793 3.17e-204 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HEGIFEPM_01794 7.55e-44 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HEGIFEPM_01795 2.81e-313 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HEGIFEPM_01796 4.82e-194 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HEGIFEPM_01797 9.43e-90 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HEGIFEPM_01798 1.7e-96 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
HEGIFEPM_01799 1.43e-129 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HEGIFEPM_01800 3.49e-248 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
HEGIFEPM_01801 2.33e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
HEGIFEPM_01802 4.62e-70 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
HEGIFEPM_01803 1.55e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
HEGIFEPM_01804 8.15e-125 - - - K - - - Transcriptional regulator
HEGIFEPM_01805 9.81e-27 - - - - - - - -
HEGIFEPM_01808 2.97e-41 - - - - - - - -
HEGIFEPM_01809 1.87e-74 - - - - - - - -
HEGIFEPM_01810 3.55e-127 - - - S - - - Protein conserved in bacteria
HEGIFEPM_01811 1.34e-232 - - - - - - - -
HEGIFEPM_01812 1.77e-205 - - - - - - - -
HEGIFEPM_01813 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
HEGIFEPM_01814 7.79e-85 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 Transcriptional regulator
HEGIFEPM_01815 2.29e-225 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HEGIFEPM_01816 7.77e-179 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
HEGIFEPM_01817 1.44e-31 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
HEGIFEPM_01818 1.15e-89 yqhL - - P - - - Rhodanese-like protein
HEGIFEPM_01819 6.61e-141 pepE 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
HEGIFEPM_01820 2.6e-231 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
HEGIFEPM_01821 6.33e-46 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
HEGIFEPM_01822 3.52e-153 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
HEGIFEPM_01823 9.29e-132 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HEGIFEPM_01824 5.33e-30 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HEGIFEPM_01825 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HEGIFEPM_01826 0.0 - - - S - - - membrane
HEGIFEPM_01827 4.78e-302 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HEGIFEPM_01828 3.79e-224 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HEGIFEPM_01829 3.06e-124 - - - S - - - Peptidase propeptide and YPEB domain
HEGIFEPM_01830 1.49e-126 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
HEGIFEPM_01831 4.32e-280 ylbM - - S - - - Belongs to the UPF0348 family
HEGIFEPM_01832 3.3e-180 yqeM - - Q - - - Methyltransferase
HEGIFEPM_01833 1.06e-76 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HEGIFEPM_01834 1.71e-149 yqeK - - H - - - Hydrolase, HD family
HEGIFEPM_01835 4.19e-153 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HEGIFEPM_01836 2.19e-67 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
HEGIFEPM_01837 2.21e-275 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
HEGIFEPM_01838 5.7e-127 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
HEGIFEPM_01839 6.32e-114 - - - - - - - -
HEGIFEPM_01840 9.51e-317 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
HEGIFEPM_01841 4.31e-119 racD 5.1.1.13 - G ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
HEGIFEPM_01842 1.64e-83 ydeP - - K - - - Transcriptional regulator, HxlR family
HEGIFEPM_01843 2.03e-251 qor 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HEGIFEPM_01844 7.03e-307 - - - L ko:K07478 - ko00000 AAA C-terminal domain
HEGIFEPM_01845 2.76e-74 - - - - - - - -
HEGIFEPM_01846 6.88e-73 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HEGIFEPM_01847 6.92e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
HEGIFEPM_01848 2.37e-109 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HEGIFEPM_01849 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HEGIFEPM_01850 6.05e-221 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
HEGIFEPM_01851 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
HEGIFEPM_01852 1.58e-117 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HEGIFEPM_01853 1.92e-133 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HEGIFEPM_01854 3.19e-202 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HEGIFEPM_01855 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HEGIFEPM_01856 8.51e-155 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
HEGIFEPM_01857 6.66e-39 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
HEGIFEPM_01858 1.79e-125 - - - S - - - Protein of unknown function (DUF2975)
HEGIFEPM_01859 4.4e-97 - - - - - - - -
HEGIFEPM_01860 1.1e-228 - - - - - - - -
HEGIFEPM_01861 1.89e-158 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase
HEGIFEPM_01862 2.1e-129 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 Nitrate reductase delta subunit
HEGIFEPM_01863 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
HEGIFEPM_01864 0.0 narZ 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HEGIFEPM_01865 8.23e-247 moeB 2.7.7.80 - H ko:K21029 ko04122,map04122 ko00000,ko00001,ko01000 ThiF family
HEGIFEPM_01866 5.46e-108 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
HEGIFEPM_01867 7.39e-294 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 MoeA N-terminal region (domain I and II)
HEGIFEPM_01868 9.62e-116 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
HEGIFEPM_01869 7.04e-108 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HEGIFEPM_01870 2.65e-127 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HEGIFEPM_01871 8.84e-52 - - - - - - - -
HEGIFEPM_01872 3e-98 - 2.7.13.3 - T ko:K07683,ko:K10851 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 phosphoenolpyruvate-protein phosphotransferase activity
HEGIFEPM_01873 1.21e-243 nreB 2.7.13.3 - F ko:K07683 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Sensor histidine kinase
HEGIFEPM_01874 5.46e-152 nreC - - K ko:K07696 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 PFAM regulatory protein LuxR
HEGIFEPM_01875 3.67e-65 - - - - - - - -
HEGIFEPM_01876 4.32e-233 - - - - - - - -
HEGIFEPM_01877 4.87e-205 - - - H - - - geranyltranstransferase activity
HEGIFEPM_01878 7.79e-203 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
HEGIFEPM_01879 4.08e-78 - - - S - - - Iron-sulfur cluster assembly protein
HEGIFEPM_01880 1.98e-278 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 Transporter, major facilitator family protein
HEGIFEPM_01881 3.23e-247 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HEGIFEPM_01882 7.86e-46 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 ThiS family
HEGIFEPM_01883 6.26e-92 moaE 2.8.1.12 - H ko:K03635,ko:K21142 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 MoaE protein
HEGIFEPM_01884 6.7e-107 - - - C - - - Flavodoxin
HEGIFEPM_01885 2.79e-212 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEGIFEPM_01886 3.26e-177 fecE 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
HEGIFEPM_01887 1.06e-239 fecB - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
HEGIFEPM_01888 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
HEGIFEPM_01889 2.71e-108 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
HEGIFEPM_01890 9.08e-299 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HEGIFEPM_01891 5.21e-311 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
HEGIFEPM_01892 1.1e-184 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
HEGIFEPM_01893 2.87e-47 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain
HEGIFEPM_01894 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
HEGIFEPM_01895 3.04e-29 - - - S - - - Virus attachment protein p12 family
HEGIFEPM_01896 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
HEGIFEPM_01897 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
HEGIFEPM_01898 4.5e-149 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HEGIFEPM_01899 2.94e-71 ytzB - - S - - - Peptidase propeptide and YPEB domain
HEGIFEPM_01900 4.7e-156 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HEGIFEPM_01901 2.14e-159 ytmP - - M - - - Choline/ethanolamine kinase
HEGIFEPM_01902 4.08e-12 ytmP - - M - - - Choline/ethanolamine kinase
HEGIFEPM_01903 2.01e-285 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
HEGIFEPM_01904 1.1e-174 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HEGIFEPM_01905 2.96e-105 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
HEGIFEPM_01906 6.76e-73 - - - - - - - -
HEGIFEPM_01907 1.09e-196 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HEGIFEPM_01908 5.76e-135 - - - S - - - WxL domain surface cell wall-binding
HEGIFEPM_01909 6.93e-139 - - - S - - - WxL domain surface cell wall-binding
HEGIFEPM_01910 3.36e-248 - - - S - - - Fn3-like domain
HEGIFEPM_01911 1.16e-80 - - - - - - - -
HEGIFEPM_01912 0.0 - - - - - - - -
HEGIFEPM_01913 3e-308 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
HEGIFEPM_01914 4.89e-146 - - - K - - - Bacterial regulatory proteins, tetR family
HEGIFEPM_01915 3.3e-151 crp2 - - K ko:K10914,ko:K21562 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
HEGIFEPM_01916 3.39e-138 - - - - - - - -
HEGIFEPM_01917 5.21e-137 - - - S ko:K09962 - ko00000 Nucleotidyltransferase
HEGIFEPM_01918 1.05e-107 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HEGIFEPM_01919 1.86e-287 ribA 3.5.4.25, 4.1.99.12 - H ko:K02858,ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HEGIFEPM_01920 8.71e-111 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
HEGIFEPM_01921 1.22e-217 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HEGIFEPM_01922 0.0 - - - S - - - membrane
HEGIFEPM_01923 8.12e-90 - - - S - - - NUDIX domain
HEGIFEPM_01924 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HEGIFEPM_01925 1.91e-234 ykoT - - M - - - Glycosyl transferase family 2
HEGIFEPM_01926 0.0 - - - L - - - MutS domain V
HEGIFEPM_01927 0.0 - - - L - - - ATPase domain of DNA mismatch repair MUTS family
HEGIFEPM_01928 2.36e-252 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HEGIFEPM_01929 0.0 - - - P - - - Cation transporter/ATPase, N-terminus
HEGIFEPM_01930 1.81e-64 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HEGIFEPM_01931 6.28e-69 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HEGIFEPM_01932 7.13e-59 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HEGIFEPM_01933 6.42e-168 - - - M - - - domain protein
HEGIFEPM_01934 1.78e-72 - - - M - - - domain protein
HEGIFEPM_01935 2.36e-100 - 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside 2-deoxyribosyltransferase
HEGIFEPM_01936 4.43e-129 - - - - - - - -
HEGIFEPM_01937 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
HEGIFEPM_01938 9.9e-144 - - - S - - - NADPH-dependent FMN reductase
HEGIFEPM_01939 1.09e-225 - - - K - - - LysR substrate binding domain
HEGIFEPM_01940 2.81e-232 - - - M - - - Peptidase family S41
HEGIFEPM_01941 2.14e-275 - - - - - - - -
HEGIFEPM_01942 1.03e-240 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
HEGIFEPM_01943 0.0 yhaN - - L - - - AAA domain
HEGIFEPM_01944 4.47e-296 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
HEGIFEPM_01945 5.76e-70 yheA - - S - - - Belongs to the UPF0342 family
HEGIFEPM_01946 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HEGIFEPM_01947 2.43e-18 - - - - - - - -
HEGIFEPM_01948 2.07e-102 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
HEGIFEPM_01949 3.23e-270 arcT - - E - - - Aminotransferase
HEGIFEPM_01950 8.08e-133 argO - - S ko:K06895 - ko00000,ko02000 LysE type translocator
HEGIFEPM_01951 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 Alanine-glyoxylate amino-transferase
HEGIFEPM_01952 1.65e-46 dltC2 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEGIFEPM_01953 1.72e-148 yciB - - M - - - ErfK YbiS YcfS YnhG
HEGIFEPM_01954 1.28e-263 - - - EGP ko:K08218 ko01501,map01501 ko00000,ko00001,ko00002,ko02000 Major facilitator Superfamily
HEGIFEPM_01955 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HEGIFEPM_01956 4.29e-310 - - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEGIFEPM_01957 4.9e-64 - 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HEGIFEPM_01958 5.81e-69 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
HEGIFEPM_01959 2.7e-104 - - - S - - - Domain of unknown function (DUF3284)
HEGIFEPM_01960 1.12e-131 celR - - K - - - PRD domain
HEGIFEPM_01961 0.0 celR - - K - - - PRD domain
HEGIFEPM_01962 6.25e-138 - - - - - - - -
HEGIFEPM_01963 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
HEGIFEPM_01964 2.91e-109 - - - - - - - -
HEGIFEPM_01965 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
HEGIFEPM_01966 7.02e-103 yybD - - S ko:K02348 - ko00000 Acetyltransferase (GNAT) domain
HEGIFEPM_01969 1.79e-42 - - - - - - - -
HEGIFEPM_01970 2.69e-316 dinF - - V - - - MatE
HEGIFEPM_01971 0.0 - - - P - - - Sodium:sulfate symporter transmembrane region
HEGIFEPM_01972 0.0 astA 2.8.2.22 - M ko:K01023 - ko00000,ko01000 Arylsulfotransferase Ig-like domain
HEGIFEPM_01973 6.91e-234 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain
HEGIFEPM_01974 2.24e-146 cysC 2.7.1.25 - F ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
HEGIFEPM_01975 1.8e-292 sat 2.7.7.4 - H ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
HEGIFEPM_01976 0.0 - - - S - - - Protein conserved in bacteria
HEGIFEPM_01977 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HEGIFEPM_01978 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HEGIFEPM_01979 8.01e-77 - - - S - - - Protein of unknown function (DUF1516)
HEGIFEPM_01980 4.91e-117 gtcA1 - - S - - - Teichoic acid glycosylation protein
HEGIFEPM_01981 5.3e-235 - - - - - - - -
HEGIFEPM_01982 9.03e-16 - - - - - - - -
HEGIFEPM_01983 4.29e-87 - - - - - - - -
HEGIFEPM_01986 2.8e-77 uvrA2 - - L - - - ABC transporter
HEGIFEPM_01987 0.0 uvrA2 - - L - - - ABC transporter
HEGIFEPM_01988 7.12e-62 - - - - - - - -
HEGIFEPM_01989 8.82e-119 - - - - - - - -
HEGIFEPM_01990 2.2e-111 ohrR - - K ko:K18906 - ko00000,ko00002,ko01504,ko03000 helix_turn_helix multiple antibiotic resistance protein
HEGIFEPM_01991 4.31e-146 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
HEGIFEPM_01992 4.56e-78 - - - - - - - -
HEGIFEPM_01993 5.37e-74 - - - - - - - -
HEGIFEPM_01994 9.01e-179 agrA - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
HEGIFEPM_01995 1.78e-284 pltK 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
HEGIFEPM_01996 7.83e-140 - - - - - - - -
HEGIFEPM_01997 4.65e-190 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
HEGIFEPM_01998 7.69e-204 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HEGIFEPM_01999 1.64e-151 - - - GM - - - NAD(P)H-binding
HEGIFEPM_02000 5.2e-85 - - - K - - - helix_turn_helix, mercury resistance
HEGIFEPM_02001 2.95e-199 mrsA1 1.8.4.11 - O ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HEGIFEPM_02002 1.49e-225 - - - K ko:K01990 - ko00000,ko00002,ko02000 LytTr DNA-binding domain
HEGIFEPM_02003 4.86e-198 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HEGIFEPM_02004 6.73e-160 - - - V ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
HEGIFEPM_02006 8.46e-317 XK27_06930 - - V ko:K01421 - ko00000 domain protein
HEGIFEPM_02007 3.55e-72 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HEGIFEPM_02008 2.07e-155 dgk2 - - F - - - deoxynucleoside kinase
HEGIFEPM_02009 7.74e-162 glpQ1 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
HEGIFEPM_02010 0.0 ugpB - - G ko:K05813 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HEGIFEPM_02011 3.05e-193 ugpE - - G ko:K05815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HEGIFEPM_02012 2.27e-221 ugpA - - U ko:K02025,ko:K05814 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HEGIFEPM_02013 1.02e-258 ugpC 3.6.3.20 - E ko:K05816,ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the ABC transporter superfamily
HEGIFEPM_02014 2.16e-109 - - - T - - - Belongs to the universal stress protein A family
HEGIFEPM_02015 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
HEGIFEPM_02016 7.77e-196 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HEGIFEPM_02017 5.04e-176 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HEGIFEPM_02018 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
HEGIFEPM_02019 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
HEGIFEPM_02020 1.03e-160 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
HEGIFEPM_02021 3.03e-122 mraW1 - - J - - - Putative rRNA methylase
HEGIFEPM_02022 9.32e-40 - - - - - - - -
HEGIFEPM_02023 0.0 tagE3 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HEGIFEPM_02024 0.0 tagE2 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HEGIFEPM_02025 7.22e-256 - - - S - - - Pfam Methyltransferase
HEGIFEPM_02026 1.46e-260 - - - N - - - Cell shape-determining protein MreB
HEGIFEPM_02027 0.0 mdr - - EGP - - - Major Facilitator
HEGIFEPM_02028 2.78e-273 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HEGIFEPM_02029 2.75e-156 - - - - - - - -
HEGIFEPM_02030 5.45e-168 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HEGIFEPM_02031 1.97e-179 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HEGIFEPM_02032 4.76e-217 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
HEGIFEPM_02033 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
HEGIFEPM_02034 3.59e-240 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
HEGIFEPM_02035 8.01e-294 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HEGIFEPM_02037 8.44e-200 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
HEGIFEPM_02038 1.58e-122 - - - K - - - Acetyltransferase (GNAT) domain
HEGIFEPM_02039 1.25e-124 - - - - - - - -
HEGIFEPM_02040 5.46e-238 - - - P ko:K06901 - ko00000,ko02000 secondary active sulfate transmembrane transporter activity
HEGIFEPM_02041 3.26e-119 - 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Phosphoribosyl transferase domain
HEGIFEPM_02053 1.35e-55 - - - S - - - COG NOG38524 non supervised orthologous group
HEGIFEPM_02056 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HEGIFEPM_02057 1.56e-46 ykuJ - - S - - - Protein of unknown function (DUF1797)
HEGIFEPM_02058 5.8e-291 araT - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HEGIFEPM_02059 6.56e-292 dacA2 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HEGIFEPM_02060 2.16e-241 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HEGIFEPM_02061 2.04e-254 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
HEGIFEPM_02062 2.34e-284 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
HEGIFEPM_02063 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HEGIFEPM_02064 1.24e-52 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
HEGIFEPM_02065 5.6e-41 - - - - - - - -
HEGIFEPM_02066 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
HEGIFEPM_02067 1.45e-131 - - - L - - - Integrase
HEGIFEPM_02068 3.4e-85 - - - K - - - Winged helix DNA-binding domain
HEGIFEPM_02069 5.67e-231 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HEGIFEPM_02070 4.86e-258 oppD - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HEGIFEPM_02071 3.59e-241 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEGIFEPM_02072 3.44e-210 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEGIFEPM_02073 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HEGIFEPM_02074 3.85e-76 ywjH - - S - - - Protein of unknown function (DUF1634)
HEGIFEPM_02075 1.01e-172 - - - S ko:K07090 - ko00000 membrane transporter protein
HEGIFEPM_02076 1.36e-208 lysR5 - - K - - - LysR substrate binding domain
HEGIFEPM_02077 4.99e-251 - - - M - - - MucBP domain
HEGIFEPM_02078 0.0 - - - - - - - -
HEGIFEPM_02079 4.5e-183 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HEGIFEPM_02080 7.08e-180 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HEGIFEPM_02081 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
HEGIFEPM_02082 1.22e-218 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
HEGIFEPM_02083 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
HEGIFEPM_02084 7.89e-290 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
HEGIFEPM_02085 6.04e-94 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Glycerol-3-phosphate cytidylyltransferase
HEGIFEPM_02086 1.13e-257 yueF - - S - - - AI-2E family transporter
HEGIFEPM_02087 7.3e-216 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
HEGIFEPM_02088 1.67e-166 pbpX - - V - - - Beta-lactamase
HEGIFEPM_02089 7.17e-39 - - - S - - - Antitoxin component of a toxin-antitoxin (TA) module
HEGIFEPM_02090 8.01e-64 - - - K - - - sequence-specific DNA binding
HEGIFEPM_02091 3.93e-172 lytE - - M - - - NlpC/P60 family
HEGIFEPM_02092 6.62e-138 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
HEGIFEPM_02093 1.01e-181 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
HEGIFEPM_02094 1.9e-168 - - - - - - - -
HEGIFEPM_02095 6.87e-131 - - - K - - - DNA-templated transcription, initiation
HEGIFEPM_02096 1.35e-34 - - - - - - - -
HEGIFEPM_02097 1.95e-41 - - - - - - - -
HEGIFEPM_02098 1.04e-45 - - - S - - - Protein of unknown function (DUF2922)
HEGIFEPM_02099 9.02e-70 - - - - - - - -
HEGIFEPM_02100 1.38e-155 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
HEGIFEPM_02101 3.65e-227 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
HEGIFEPM_02102 2.94e-190 cps3J - - M - - - Domain of unknown function (DUF4422)
HEGIFEPM_02103 5.67e-257 cps3I - - G - - - Acyltransferase family
HEGIFEPM_02104 1.24e-256 cps3H - - - - - - -
HEGIFEPM_02105 2.71e-199 cps3F - - - - - - -
HEGIFEPM_02106 1.45e-145 cps3E - - - - - - -
HEGIFEPM_02107 4.14e-260 cps3D - - - - - - -
HEGIFEPM_02108 1.15e-281 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
HEGIFEPM_02109 7.72e-228 cps3B - - S ko:K07011 - ko00000 Glycosyltransferase like family 2
HEGIFEPM_02110 3.86e-167 cps3A - - S ko:K07011 - ko00000 Glycosyltransferase like family 2
HEGIFEPM_02111 2.29e-24 cps2K - - L ko:K07473 - ko00000,ko02048 bacterial-type proximal promoter sequence-specific DNA binding
HEGIFEPM_02112 4.47e-40 - - - G - - - Acyltransferase family
HEGIFEPM_02113 9.96e-139 - - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
HEGIFEPM_02114 7.12e-23 - - - M - - - Glycosyltransferase like family 2
HEGIFEPM_02115 2.9e-14 - - - S - - - Glycosyltransferase like family 2
HEGIFEPM_02116 9.28e-43 - - - S - - - Core-2/I-Branching enzyme
HEGIFEPM_02117 2.38e-52 tagB 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HEGIFEPM_02118 8.59e-18 tagB 2.7.8.12 - M ko:K09809 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HEGIFEPM_02120 1.99e-70 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Glycerol-3-phosphate cytidylyltransferase
HEGIFEPM_02121 1.32e-110 - - - M - - - Glycosyl transferase family 2
HEGIFEPM_02122 1.1e-155 tuaA - - M - - - Bacterial sugar transferase
HEGIFEPM_02123 5.41e-226 cps2D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
HEGIFEPM_02124 5.21e-179 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
HEGIFEPM_02125 1.74e-165 ywqD - - D - - - Capsular exopolysaccharide family
HEGIFEPM_02126 1.42e-171 epsB - - M - - - biosynthesis protein
HEGIFEPM_02127 2.65e-129 - - - L - - - Integrase
HEGIFEPM_02128 3.61e-198 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HEGIFEPM_02129 2.33e-95 - - - M - - - KxYKxGKxW signal domain protein
HEGIFEPM_02131 6.58e-87 icaB - - G ko:K21478 - ko00000,ko01000 Polysaccharide deacetylase
HEGIFEPM_02132 6.04e-42 - - - G - - - Acyltransferase family
HEGIFEPM_02133 8.45e-228 cps2J - - S - - - Polysaccharide biosynthesis protein
HEGIFEPM_02134 8.38e-45 - - - S - - - Polysaccharide pyruvyl transferase
HEGIFEPM_02135 5.02e-82 - - - M - - - Glycosyltransferase like family 2
HEGIFEPM_02136 1.49e-133 - - - P ko:K19419 - ko00000,ko02000 EpsG family
HEGIFEPM_02137 1.44e-76 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HEGIFEPM_02138 2.25e-50 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HEGIFEPM_02139 6.98e-83 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HEGIFEPM_02140 5.11e-74 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HEGIFEPM_02141 1.36e-79 - 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase-like
HEGIFEPM_02142 3.23e-75 - - - S - - - Glycosyltransferase family 28 C-terminal domain
HEGIFEPM_02143 5.24e-97 - - - M - - - Oligosaccharide biosynthesis protein Alg14 like
HEGIFEPM_02144 8.13e-118 - - - M - - - Parallel beta-helix repeats
HEGIFEPM_02145 3.13e-05 pbpX2 - - V - - - Beta-lactamase
HEGIFEPM_02146 4.35e-12 - - - DM - - - AAA domain
HEGIFEPM_02147 1.27e-58 - - - M - - - biosynthesis protein
HEGIFEPM_02148 8.03e-169 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HEGIFEPM_02149 1.23e-200 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
HEGIFEPM_02150 2.74e-266 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HEGIFEPM_02151 1.63e-281 pbpX - - V - - - Beta-lactamase
HEGIFEPM_02152 0.0 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
HEGIFEPM_02153 2.9e-139 - - - - - - - -
HEGIFEPM_02154 7.62e-97 - - - - - - - -
HEGIFEPM_02156 1.93e-210 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HEGIFEPM_02157 6.59e-315 pts14C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEGIFEPM_02158 3.93e-99 - - - T - - - Universal stress protein family
HEGIFEPM_02160 3.03e-313 yfmL - - L - - - DEAD DEAH box helicase
HEGIFEPM_02161 1.94e-245 mocA - - S - - - Oxidoreductase
HEGIFEPM_02162 6.22e-43 cspP - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
HEGIFEPM_02163 8.58e-82 - - - S - - - Domain of unknown function (DUF4828)
HEGIFEPM_02164 4.68e-187 lys - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
HEGIFEPM_02165 5.63e-196 gntR - - K - - - rpiR family
HEGIFEPM_02166 2.87e-215 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HEGIFEPM_02167 7.06e-307 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEGIFEPM_02168 0.0 yfgQ - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
HEGIFEPM_02169 5.56e-130 yobS - - K - - - Bacterial regulatory proteins, tetR family
HEGIFEPM_02170 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HEGIFEPM_02171 1.59e-242 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
HEGIFEPM_02172 4.32e-256 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HEGIFEPM_02173 4.54e-77 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HEGIFEPM_02174 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HEGIFEPM_02175 5.11e-67 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HEGIFEPM_02176 9.48e-263 camS - - S - - - sex pheromone
HEGIFEPM_02177 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HEGIFEPM_02178 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
HEGIFEPM_02179 1.39e-279 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HEGIFEPM_02180 2.67e-119 yebE - - S - - - UPF0316 protein
HEGIFEPM_02181 2.01e-134 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HEGIFEPM_02182 2.92e-147 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
HEGIFEPM_02183 9.47e-236 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
HEGIFEPM_02184 8.5e-213 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
HEGIFEPM_02185 2.81e-201 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HEGIFEPM_02186 1.89e-208 - - - S - - - L,D-transpeptidase catalytic domain
HEGIFEPM_02187 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HEGIFEPM_02188 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HEGIFEPM_02189 7.76e-234 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
HEGIFEPM_02190 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
HEGIFEPM_02191 0.0 - - - S ko:K06889 - ko00000 Alpha beta
HEGIFEPM_02192 6.07e-33 - - - - - - - -
HEGIFEPM_02193 4.37e-128 - - - S - - - ECF transporter, substrate-specific component
HEGIFEPM_02194 0.0 - - - E ko:K03294 - ko00000 Amino Acid
HEGIFEPM_02195 3.7e-212 mleP2 - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
HEGIFEPM_02196 0.0 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
HEGIFEPM_02197 5.21e-81 mleR - - K - - - LysR family
HEGIFEPM_02198 1.99e-107 mleR - - K - - - LysR family
HEGIFEPM_02199 4.54e-207 mleR2 - - K - - - LysR family transcriptional regulator
HEGIFEPM_02200 1.98e-122 citX 2.7.7.61 - HI ko:K05964 ko02020,map02020 ko00000,ko00001,ko01000 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HEGIFEPM_02201 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
HEGIFEPM_02202 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HEGIFEPM_02203 3.04e-274 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HEGIFEPM_02204 4.91e-19 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HEGIFEPM_02208 6.7e-104 - - - K - - - sequence-specific DNA binding
HEGIFEPM_02209 4.11e-217 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
HEGIFEPM_02210 0.0 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
HEGIFEPM_02211 9.11e-208 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
HEGIFEPM_02212 1.23e-58 citD - - C ko:K01646 ko02020,map02020 ko00000,ko00001 Covalent carrier of the coenzyme of citrate lyase
HEGIFEPM_02213 5.31e-242 citC 6.2.1.22 - H ko:K01910 ko02020,map02020 ko00000,ko00001,ko01000 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HEGIFEPM_02214 3.19e-263 mae 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme, NAD binding domain
HEGIFEPM_02215 8.69e-230 citR - - K - - - sugar-binding domain protein
HEGIFEPM_02216 0.0 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
HEGIFEPM_02217 7.56e-214 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HEGIFEPM_02218 1.18e-66 - - - - - - - -
HEGIFEPM_02219 8.6e-222 mntA - - P ko:K19975,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HEGIFEPM_02220 3.54e-180 mtsB - - U ko:K19972,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
HEGIFEPM_02221 2.04e-170 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HEGIFEPM_02222 2.23e-196 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HEGIFEPM_02223 1.55e-254 - - - K - - - Helix-turn-helix domain
HEGIFEPM_02224 2.1e-211 ttdA 4.2.1.32 - C ko:K03779 ko00630,map00630 ko00000,ko00001,ko01000 Fumarate hydratase (Fumerase)
HEGIFEPM_02225 1.41e-147 - 4.2.1.2, 4.2.1.32 - C ko:K01676,ko:K03780 ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible hydration of fumarate to (S)- malate
HEGIFEPM_02226 1.51e-69 yitW - - S - - - Iron-sulfur cluster assembly protein
HEGIFEPM_02227 0.0 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
HEGIFEPM_02228 8.14e-51 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HEGIFEPM_02229 8.1e-179 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HEGIFEPM_02230 3.3e-235 aroF 2.5.1.54 - E ko:K03856 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 DAHP synthetase I family
HEGIFEPM_02231 2.45e-213 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HEGIFEPM_02232 0.0 tkt2 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HEGIFEPM_02233 1.35e-261 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
HEGIFEPM_02234 8.22e-234 - - - S - - - Membrane
HEGIFEPM_02235 8.51e-210 yitS - - S - - - Uncharacterised protein, DegV family COG1307
HEGIFEPM_02236 0.0 sthIR 3.1.21.5 - S ko:K01156 - ko00000,ko01000,ko02048 Type III restriction
HEGIFEPM_02237 1.49e-26 - 2.1.1.72 - L ko:K07316 - ko00000,ko01000,ko02048 DNA methylase
HEGIFEPM_02238 4.48e-175 - 2.1.1.72 - L ko:K00571,ko:K07316 - ko00000,ko01000,ko02048 DNA methylase
HEGIFEPM_02239 1.22e-105 - 2.1.1.72 - L ko:K07316 - ko00000,ko01000,ko02048 DNA methylase
HEGIFEPM_02242 2.29e-72 - - - - - - - -
HEGIFEPM_02243 6.78e-248 - - - - - - - -
HEGIFEPM_02244 8.27e-160 - - - O - - - RNA helicase
HEGIFEPM_02245 3.43e-21 - - - S - - - Helix-turn-helix domain
HEGIFEPM_02246 1.35e-16 int - - L - - - Phage integrase family
HEGIFEPM_02247 1.03e-193 int - - L - - - Belongs to the 'phage' integrase family
HEGIFEPM_02248 8.98e-86 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
HEGIFEPM_02249 4.58e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HEGIFEPM_02250 3.06e-194 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HEGIFEPM_02251 5.35e-125 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEGIFEPM_02252 3.47e-212 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEGIFEPM_02253 1.98e-197 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEGIFEPM_02254 1.07e-264 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HEGIFEPM_02255 9.15e-194 - - - S - - - FMN_bind
HEGIFEPM_02256 0.0 ndh 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HEGIFEPM_02257 2.19e-111 - - - S - - - NusG domain II
HEGIFEPM_02258 1.41e-122 hepA 2.5.1.30 - S ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase component I
HEGIFEPM_02259 1.19e-232 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HEGIFEPM_02260 7.76e-81 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
HEGIFEPM_02261 2.19e-220 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEGIFEPM_02262 7.71e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HEGIFEPM_02263 9.65e-79 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HEGIFEPM_02264 9.87e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HEGIFEPM_02265 1.84e-160 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HEGIFEPM_02266 5.95e-300 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HEGIFEPM_02267 1.09e-90 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
HEGIFEPM_02268 8.44e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
HEGIFEPM_02269 5.32e-109 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HEGIFEPM_02270 1.75e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HEGIFEPM_02271 2.14e-123 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HEGIFEPM_02272 4.99e-88 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HEGIFEPM_02273 3.53e-123 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HEGIFEPM_02274 4.1e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HEGIFEPM_02275 2.98e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HEGIFEPM_02276 1.96e-54 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HEGIFEPM_02277 1.11e-33 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
HEGIFEPM_02278 8.29e-100 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HEGIFEPM_02279 5.46e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HEGIFEPM_02280 3.59e-69 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HEGIFEPM_02281 1.85e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HEGIFEPM_02282 6.61e-193 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HEGIFEPM_02283 2.27e-59 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HEGIFEPM_02284 9.83e-141 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
HEGIFEPM_02285 4.34e-145 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HEGIFEPM_02286 4.46e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
HEGIFEPM_02287 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HEGIFEPM_02288 1.19e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HEGIFEPM_02289 4.19e-92 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HEGIFEPM_02290 6.04e-149 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
HEGIFEPM_02291 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEGIFEPM_02292 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEGIFEPM_02293 1.16e-140 - - - K - - - Bacterial regulatory proteins, tetR family
HEGIFEPM_02294 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HEGIFEPM_02295 9.78e-102 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
HEGIFEPM_02303 1.62e-294 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HEGIFEPM_02304 1.11e-148 dgk2 - - F - - - deoxynucleoside kinase
HEGIFEPM_02305 5.9e-100 dacB 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
HEGIFEPM_02306 0.0 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
HEGIFEPM_02307 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
HEGIFEPM_02308 1.7e-118 - - - K - - - Transcriptional regulator
HEGIFEPM_02309 3.03e-129 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HEGIFEPM_02310 2.24e-197 - - - I - - - alpha/beta hydrolase fold
HEGIFEPM_02311 2.05e-153 - - - I - - - phosphatase
HEGIFEPM_02312 2.34e-242 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HEGIFEPM_02313 7.76e-100 - - - S - - - Threonine/Serine exporter, ThrE
HEGIFEPM_02314 2.66e-168 - - - S - - - Putative threonine/serine exporter
HEGIFEPM_02315 1.78e-42 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
HEGIFEPM_02316 7.39e-139 mntR - - K ko:K03709 - ko00000,ko03000 iron dependent repressor
HEGIFEPM_02317 1.36e-77 - - - - - - - -
HEGIFEPM_02318 7.79e-112 - - - K - - - MerR HTH family regulatory protein
HEGIFEPM_02319 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
HEGIFEPM_02320 2.72e-152 - - - S - - - Domain of unknown function (DUF4811)
HEGIFEPM_02321 9.04e-179 - - - - - - - -
HEGIFEPM_02322 1.75e-47 - - - K - - - MerR HTH family regulatory protein
HEGIFEPM_02323 1.43e-155 azlC - - E - - - branched-chain amino acid
HEGIFEPM_02324 2.41e-66 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
HEGIFEPM_02325 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
HEGIFEPM_02326 1.2e-281 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Amino acid kinase family
HEGIFEPM_02327 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HEGIFEPM_02328 0.0 xylP2 - - G - - - symporter
HEGIFEPM_02329 3.48e-245 - - - I - - - alpha/beta hydrolase fold
HEGIFEPM_02330 3.33e-64 - - - - - - - -
HEGIFEPM_02331 1.91e-272 gudD 4.2.1.40 - M ko:K01706 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain
HEGIFEPM_02332 4.58e-90 - - - K - - - LysR substrate binding domain
HEGIFEPM_02333 4.77e-161 - 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HEGIFEPM_02334 2.1e-215 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
HEGIFEPM_02335 1.82e-185 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
HEGIFEPM_02336 7.18e-219 dgoD 4.2.1.6, 4.2.1.8 - M ko:K01684,ko:K08323 ko00040,ko00052,ko01100,ko01120,map00040,map00052,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Mandelate racemase muconate lactonizing enzyme
HEGIFEPM_02337 1.03e-183 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
HEGIFEPM_02338 1.5e-156 gpm5 - - G - - - Phosphoglycerate mutase family
HEGIFEPM_02339 4.09e-131 - - - K - - - FR47-like protein
HEGIFEPM_02340 8.44e-163 yibF - - S - - - overlaps another CDS with the same product name
HEGIFEPM_02341 3.42e-280 yibE - - S - - - overlaps another CDS with the same product name
HEGIFEPM_02342 6.48e-243 - - - - - - - -
HEGIFEPM_02343 1.44e-179 - - - S - - - NADPH-dependent FMN reductase
HEGIFEPM_02344 1.19e-66 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HEGIFEPM_02345 1.36e-208 rluD2 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HEGIFEPM_02346 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
HEGIFEPM_02347 4.95e-44 - - - L - - - leucine-zipper of insertion element IS481
HEGIFEPM_02348 5.44e-56 - - - - - - - -
HEGIFEPM_02349 8.91e-289 - - - L - - - DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HEGIFEPM_02350 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HEGIFEPM_02351 3.39e-255 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
HEGIFEPM_02352 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
HEGIFEPM_02353 4.71e-149 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HEGIFEPM_02354 6.11e-106 - - - K - - - Transcriptional regulator
HEGIFEPM_02356 0.0 - - - C - - - FMN_bind
HEGIFEPM_02357 1.6e-219 - - - K - - - Transcriptional regulator
HEGIFEPM_02358 1.09e-123 - - - K - - - Helix-turn-helix domain
HEGIFEPM_02359 1.83e-180 - - - K - - - sequence-specific DNA binding
HEGIFEPM_02360 1.42e-112 - - - S - - - AAA domain
HEGIFEPM_02361 1.42e-08 - - - - - - - -
HEGIFEPM_02362 0.0 - - - M - - - MucBP domain
HEGIFEPM_02363 1.39e-118 XK27_09665 - - G ko:K15640 - ko00000 Phosphoglycerate mutase family
HEGIFEPM_02365 9.26e-98 - - - L - - - PFAM Integrase catalytic region
HEGIFEPM_02366 9.03e-73 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
HEGIFEPM_02367 0.000211 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
HEGIFEPM_02368 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
HEGIFEPM_02369 2.66e-132 - - - G - - - Glycogen debranching enzyme
HEGIFEPM_02370 5.21e-62 - 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
HEGIFEPM_02371 3.27e-215 yjdB - - S - - - Domain of unknown function (DUF4767)
HEGIFEPM_02372 1.31e-188 yisK 3.7.1.5, 4.1.1.68 - Q ko:K05921,ko:K16164 ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Fumarylacetoacetate (FAA) hydrolase family
HEGIFEPM_02373 1.04e-94 asp2 - - S - - - Asp23 family, cell envelope-related function
HEGIFEPM_02374 1.1e-93 asp1 - - S - - - Asp23 family, cell envelope-related function
HEGIFEPM_02375 5.74e-32 - - - - - - - -
HEGIFEPM_02376 1.95e-116 - - - - - - - -
HEGIFEPM_02377 1.81e-50 ydaS - - S - - - Transglycosylase associated protein
HEGIFEPM_02378 0.0 XK27_09800 - - I - - - Acyltransferase family
HEGIFEPM_02379 6.66e-57 - - - S - - - MORN repeat
HEGIFEPM_02380 1.07e-295 - - - S - - - Cysteine-rich secretory protein family
HEGIFEPM_02381 4.73e-302 yceJ - - EGP ko:K08221 - ko00000,ko02000 transporter
HEGIFEPM_02382 1.85e-75 - - - K - - - HxlR-like helix-turn-helix
HEGIFEPM_02383 2.01e-149 XK27_07075 - - V ko:K07052 - ko00000 CAAX protease self-immunity
HEGIFEPM_02384 0.0 - - - L - - - AAA domain
HEGIFEPM_02385 2.27e-82 - - - K - - - Helix-turn-helix domain
HEGIFEPM_02386 1.08e-71 - - - - - - - -
HEGIFEPM_02387 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
HEGIFEPM_02388 3.69e-230 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
HEGIFEPM_02389 1.46e-211 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Nitronate monooxygenase
HEGIFEPM_02390 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
HEGIFEPM_02391 1.35e-144 - - - S ko:K03975 - ko00000 SNARE associated Golgi protein
HEGIFEPM_02392 5.06e-228 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
HEGIFEPM_02393 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
HEGIFEPM_02394 9.61e-14 gpm2 - - G - - - Phosphoglycerate mutase family
HEGIFEPM_02395 3.67e-115 gpm2 - - G - - - Phosphoglycerate mutase family
HEGIFEPM_02396 2.61e-163 pgm3 - - G - - - Phosphoglycerate mutase family
HEGIFEPM_02397 1.61e-36 - - - - - - - -
HEGIFEPM_02398 3.5e-64 sugE - - U ko:K11741 - ko00000,ko02000 Multidrug resistance protein
HEGIFEPM_02399 1.13e-102 rppH3 - - F - - - NUDIX domain
HEGIFEPM_02400 2.42e-299 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HEGIFEPM_02401 1.05e-127 - - - K - - - Bacterial regulatory proteins, tetR family
HEGIFEPM_02402 2.93e-109 - - - S ko:K07090 - ko00000 membrane transporter protein
HEGIFEPM_02403 2.27e-269 - - - EGP - - - Major Facilitator Superfamily
HEGIFEPM_02404 5.4e-44 - - - K - - - MarR family
HEGIFEPM_02405 1.1e-18 - - - K - - - MarR family
HEGIFEPM_02406 2.97e-189 - - - S - - - Sulfite exporter TauE/SafE
HEGIFEPM_02407 3.1e-96 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HEGIFEPM_02408 0.0 steT - - E ko:K03294 - ko00000 amino acid
HEGIFEPM_02409 1.57e-182 - 3.5.1.105 - G ko:K03478 - ko00000,ko01000 YdjC-like protein
HEGIFEPM_02410 0.0 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
HEGIFEPM_02411 1.1e-196 - - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
HEGIFEPM_02412 2.1e-109 - - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HEGIFEPM_02413 1.27e-141 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HEGIFEPM_02414 3.14e-140 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HEGIFEPM_02415 3.39e-190 glnH - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HEGIFEPM_02416 2.3e-172 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HEGIFEPM_02418 1.28e-54 - - - - - - - -
HEGIFEPM_02419 2.95e-217 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEGIFEPM_02420 7.9e-269 aspC 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HEGIFEPM_02421 6.94e-146 gph1 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 HAD hydrolase, family IA, variant
HEGIFEPM_02422 1.01e-188 - - - - - - - -
HEGIFEPM_02423 8.84e-18 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
HEGIFEPM_02424 2.02e-106 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
HEGIFEPM_02425 7.32e-136 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
HEGIFEPM_02426 1.48e-27 - - - - - - - -
HEGIFEPM_02427 7.48e-96 - - - F - - - Nudix hydrolase
HEGIFEPM_02428 4.49e-192 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
HEGIFEPM_02429 6.12e-115 - - - - - - - -
HEGIFEPM_02430 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
HEGIFEPM_02431 1.21e-63 - - - - - - - -
HEGIFEPM_02432 2.68e-90 - - - O - - - OsmC-like protein
HEGIFEPM_02433 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HEGIFEPM_02434 0.0 oatA - - I - - - Acyltransferase
HEGIFEPM_02435 1.23e-229 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HEGIFEPM_02436 3.45e-231 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
HEGIFEPM_02437 0.0 pox2 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
HEGIFEPM_02438 4.49e-197 ribC1 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
HEGIFEPM_02439 0.0 pox1 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
HEGIFEPM_02440 1.79e-287 pbuG - - S ko:K06901 - ko00000,ko02000 permease
HEGIFEPM_02441 1.36e-27 - - - - - - - -
HEGIFEPM_02442 6.16e-107 - - - K - - - Transcriptional regulator
HEGIFEPM_02443 6.68e-197 licD - - M ko:K07271 - ko00000,ko01000 LicD family
HEGIFEPM_02444 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
HEGIFEPM_02445 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HEGIFEPM_02446 4.45e-226 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
HEGIFEPM_02447 7.51e-104 - - - EGP - - - Major Facilitator
HEGIFEPM_02448 7.31e-84 - - - EGP - - - Major Facilitator
HEGIFEPM_02449 4.2e-117 - - - V - - - VanZ like family
HEGIFEPM_02450 3.88e-46 - - - - - - - -
HEGIFEPM_02451 5.45e-94 spx1 - - P ko:K16509 - ko00000 ArsC family
HEGIFEPM_02453 1.68e-181 - - - - - - - -
HEGIFEPM_02454 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HEGIFEPM_02455 2.09e-42 - - - G ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
HEGIFEPM_02456 1.73e-178 - - - EGP - - - Transmembrane secretion effector
HEGIFEPM_02457 7.06e-169 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
HEGIFEPM_02458 2.49e-95 - - - - - - - -
HEGIFEPM_02459 3.38e-70 - - - - - - - -
HEGIFEPM_02460 5.93e-263 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
HEGIFEPM_02461 2.01e-134 - - - K - - - Bacterial regulatory proteins, tetR family
HEGIFEPM_02462 6.61e-189 - 3.1.3.23 - S ko:K07757 - ko00000,ko01000 Sucrose-6F-phosphate phosphohydrolase
HEGIFEPM_02463 3.15e-158 - - - T - - - EAL domain
HEGIFEPM_02464 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HEGIFEPM_02465 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HEGIFEPM_02466 2.18e-182 ybbR - - S - - - YbbR-like protein
HEGIFEPM_02467 8.33e-192 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HEGIFEPM_02468 5.68e-156 - - - S - - - Protein of unknown function (DUF1361)
HEGIFEPM_02469 3.07e-119 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HEGIFEPM_02470 0.0 yvgP - - P ko:K03316 - ko00000 Sodium proton antiporter
HEGIFEPM_02471 6.24e-214 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
HEGIFEPM_02472 1.71e-210 ysjB - - S ko:K03810 - ko00000 Oxidoreductase family, NAD-binding Rossmann fold
HEGIFEPM_02473 1.03e-197 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
HEGIFEPM_02474 2.41e-129 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
HEGIFEPM_02475 2.52e-114 - - - J - - - Acetyltransferase (GNAT) domain
HEGIFEPM_02476 1.29e-105 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
HEGIFEPM_02477 1.23e-227 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
HEGIFEPM_02478 1.4e-174 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HEGIFEPM_02479 1.98e-199 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
HEGIFEPM_02480 6.57e-136 - - - - - - - -
HEGIFEPM_02481 9.36e-171 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HEGIFEPM_02482 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HEGIFEPM_02483 0.0 - - - M - - - Domain of unknown function (DUF5011)
HEGIFEPM_02484 2.4e-107 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HEGIFEPM_02485 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HEGIFEPM_02486 6.62e-180 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Serine aminopeptidase, S33
HEGIFEPM_02487 1.76e-43 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
HEGIFEPM_02488 0.0 eriC - - P ko:K03281 - ko00000 chloride
HEGIFEPM_02489 5.11e-171 - - - - - - - -
HEGIFEPM_02490 0.0 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HEGIFEPM_02491 7.15e-179 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HEGIFEPM_02492 1.31e-285 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
HEGIFEPM_02493 2.02e-245 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HEGIFEPM_02494 5.75e-242 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
HEGIFEPM_02495 1.14e-311 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 Sigma-54 factor, core binding domain
HEGIFEPM_02497 5.11e-133 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HEGIFEPM_02498 7.35e-224 - 1.1.1.26 - CH ko:K00015 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEGIFEPM_02499 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HEGIFEPM_02500 7e-215 whiA - - K ko:K09762 - ko00000 May be required for sporulation
HEGIFEPM_02501 4.56e-243 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
HEGIFEPM_02502 1.71e-207 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
HEGIFEPM_02503 1.71e-107 - - - S - - - Short repeat of unknown function (DUF308)
HEGIFEPM_02504 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
HEGIFEPM_02505 7.5e-302 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
HEGIFEPM_02506 2.21e-113 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HEGIFEPM_02507 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HEGIFEPM_02508 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HEGIFEPM_02509 9.45e-152 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
HEGIFEPM_02510 8.83e-267 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 transporter
HEGIFEPM_02511 1.89e-134 aad 3.4.13.22 - E ko:K08641 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HEGIFEPM_02512 0.0 nox2 - - S - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HEGIFEPM_02513 5.9e-170 - - - T - - - Putative diguanylate phosphodiesterase
HEGIFEPM_02514 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HEGIFEPM_02515 4.44e-27 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HEGIFEPM_02516 7.54e-99 - - - S - - - Protein of unknown function (DUF3290)
HEGIFEPM_02517 4.31e-141 yviA - - S - - - Protein of unknown function (DUF421)
HEGIFEPM_02518 8.65e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HEGIFEPM_02519 7.91e-172 - - - T - - - diguanylate cyclase activity
HEGIFEPM_02520 0.0 - - - S - - - Bacterial cellulose synthase subunit
HEGIFEPM_02521 7.92e-214 ydaM - - M - - - Glycosyl transferase family group 2
HEGIFEPM_02522 2.39e-256 - - - S - - - Protein conserved in bacteria
HEGIFEPM_02523 4.95e-310 - - - - - - - -
HEGIFEPM_02524 1.85e-81 ydaJ - - G - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
HEGIFEPM_02525 5.78e-80 ydaJ - - G - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
HEGIFEPM_02526 0.0 nox - - C - - - NADH oxidase
HEGIFEPM_02527 6.37e-160 - - - T - - - Putative diguanylate phosphodiesterase
HEGIFEPM_02528 1.13e-218 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
HEGIFEPM_02529 2.82e-235 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
HEGIFEPM_02530 1.04e-211 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HEGIFEPM_02531 2.55e-225 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HEGIFEPM_02532 2.36e-70 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
HEGIFEPM_02533 7.97e-65 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 positive regulation of macromolecule biosynthetic process
HEGIFEPM_02534 1.55e-150 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
HEGIFEPM_02535 2.31e-179 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HEGIFEPM_02536 9.78e-190 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HEGIFEPM_02537 5.04e-200 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
HEGIFEPM_02538 2.22e-206 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
HEGIFEPM_02539 6.91e-201 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
HEGIFEPM_02540 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HEGIFEPM_02541 1.49e-170 phoP - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
HEGIFEPM_02542 5.22e-276 minJ - - O - - - Domain present in PSD-95, Dlg, and ZO-1/2.
HEGIFEPM_02543 8.03e-256 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HEGIFEPM_02544 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HEGIFEPM_02545 1.27e-129 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HEGIFEPM_02546 2.82e-162 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
HEGIFEPM_02547 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
HEGIFEPM_02548 3.7e-149 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
HEGIFEPM_02549 6.57e-199 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
HEGIFEPM_02550 7.29e-247 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
HEGIFEPM_02551 0.0 ydaO - - E - - - amino acid
HEGIFEPM_02552 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HEGIFEPM_02553 9.82e-55 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HEGIFEPM_02554 2.38e-140 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
HEGIFEPM_02555 0.0 - - - L ko:K07487 - ko00000 Transposase
HEGIFEPM_02556 3.67e-154 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HEGIFEPM_02557 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
HEGIFEPM_02558 6.01e-248 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HEGIFEPM_02559 5.74e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HEGIFEPM_02560 4.66e-131 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
HEGIFEPM_02561 6.84e-167 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
HEGIFEPM_02562 2.33e-240 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter
HEGIFEPM_02563 9.33e-177 phnC 3.6.3.28 - P ko:K02041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HEGIFEPM_02564 5.35e-177 phnE2 - - U ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter permease
HEGIFEPM_02565 6.72e-184 phnE1 - - U ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HEGIFEPM_02566 1.78e-128 phnX 3.11.1.1 - E ko:K05306 ko00440,ko01100,ko01120,map00440,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the HAD-like hydrolase superfamily. PhnX family
HEGIFEPM_02567 2.38e-47 phnX 3.11.1.1 - E ko:K05306 ko00440,ko01100,ko01120,map00440,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the HAD-like hydrolase superfamily. PhnX family
HEGIFEPM_02568 9.25e-271 phnW 2.6.1.37 - E ko:K03430 ko00440,ko01100,ko01120,map00440,map01100,map01120 ko00000,ko00001,ko01000,ko01007 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
HEGIFEPM_02569 4.95e-246 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
HEGIFEPM_02570 3.17e-191 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
HEGIFEPM_02571 2.64e-213 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HEGIFEPM_02572 8.46e-77 yabA - - L - - - Involved in initiation control of chromosome replication
HEGIFEPM_02573 2.33e-239 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
HEGIFEPM_02574 1.39e-70 yaaQ - - S - - - Cyclic-di-AMP receptor
HEGIFEPM_02575 2.22e-153 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HEGIFEPM_02576 1.01e-51 yaaL - - S - - - Protein of unknown function (DUF2508)
HEGIFEPM_02577 6.22e-140 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HEGIFEPM_02578 2.05e-62 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HEGIFEPM_02579 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HEGIFEPM_02580 7.57e-119 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HEGIFEPM_02581 6.7e-141 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
HEGIFEPM_02582 8.42e-50 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
HEGIFEPM_02583 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEGIFEPM_02584 2.47e-253 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEGIFEPM_02585 2.37e-140 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
HEGIFEPM_02586 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HEGIFEPM_02587 1.78e-88 - - - L - - - nuclease
HEGIFEPM_02588 1.01e-226 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
HEGIFEPM_02589 2.76e-74 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HEGIFEPM_02590 3.72e-105 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HEGIFEPM_02591 2.69e-158 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HEGIFEPM_02592 9.76e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HEGIFEPM_02593 2.81e-202 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HEGIFEPM_02594 1.89e-128 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
HEGIFEPM_02595 1e-39 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HEGIFEPM_02596 4.55e-31 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HEGIFEPM_02597 1.12e-130 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Sigma-70 region 2
HEGIFEPM_02598 1.75e-126 yacP - - S ko:K06962 - ko00000 YacP-like NYN domain
HEGIFEPM_02599 1.49e-177 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HEGIFEPM_02600 1.35e-92 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HEGIFEPM_02601 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HEGIFEPM_02602 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HEGIFEPM_02603 4.91e-265 yacL - - S - - - domain protein
HEGIFEPM_02604 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HEGIFEPM_02605 9.43e-127 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
HEGIFEPM_02606 5.96e-69 yjdJ - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
HEGIFEPM_02607 1.62e-158 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HEGIFEPM_02608 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
HEGIFEPM_02609 1.12e-147 zmp2 - - O - - - Zinc-dependent metalloprotease
HEGIFEPM_02610 1.11e-164 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HEGIFEPM_02611 6.04e-227 - - - EG - - - EamA-like transporter family
HEGIFEPM_02612 7.53e-215 mleP2 - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
HEGIFEPM_02613 2.29e-234 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HEGIFEPM_02614 2.89e-176 accA1 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
HEGIFEPM_02615 2.58e-184 accD1 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HEGIFEPM_02616 3.78e-316 accC1 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase C-terminal domain
HEGIFEPM_02617 9.24e-85 accB1 - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin-requiring enzyme
HEGIFEPM_02618 3.15e-229 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HEGIFEPM_02619 4.5e-113 manX 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
HEGIFEPM_02620 7.19e-94 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
HEGIFEPM_02621 0.0 levR - - K - - - Sigma-54 interaction domain
HEGIFEPM_02622 9.05e-85 manO - - S - - - Domain of unknown function (DUF956)
HEGIFEPM_02623 1.87e-219 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
HEGIFEPM_02624 4.51e-172 manM - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
HEGIFEPM_02625 6.46e-218 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
HEGIFEPM_02626 3.4e-206 - - - G - - - Peptidase_C39 like family
HEGIFEPM_02628 4.52e-19 - - - - - - - -
HEGIFEPM_02632 8.77e-204 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HEGIFEPM_02633 1.71e-302 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
HEGIFEPM_02634 7.59e-107 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
HEGIFEPM_02635 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
HEGIFEPM_02636 2.57e-94 - - - - ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 -
HEGIFEPM_02637 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
HEGIFEPM_02638 2.15e-196 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HEGIFEPM_02639 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HEGIFEPM_02640 6.9e-178 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HEGIFEPM_02641 5.41e-160 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
HEGIFEPM_02642 2.92e-280 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
HEGIFEPM_02643 5.35e-175 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HEGIFEPM_02644 6.15e-195 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
HEGIFEPM_02645 9.2e-247 ysdE - - P - - - Citrate transporter
HEGIFEPM_02646 1.31e-213 pphA 3.1.3.16 - T ko:K07313 - ko00000,ko01000 Calcineurin-like phosphoesterase
HEGIFEPM_02647 1.38e-71 - - - S - - - Cupin domain
HEGIFEPM_02648 9.02e-66 - - - S - - - Cupin 2, conserved barrel domain protein
HEGIFEPM_02652 1.5e-194 - - - S - - - Calcineurin-like phosphoesterase
HEGIFEPM_02653 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
HEGIFEPM_02656 1.35e-55 - - - S - - - COG NOG38524 non supervised orthologous group
HEGIFEPM_02659 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
HEGIFEPM_02660 5.33e-243 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HEGIFEPM_02661 1.93e-209 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HEGIFEPM_02662 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HEGIFEPM_02663 4.3e-124 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
HEGIFEPM_02664 1.99e-80 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HEGIFEPM_02665 4.31e-224 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HEGIFEPM_02666 2.51e-102 yabR - - J ko:K07571 - ko00000 RNA binding
HEGIFEPM_02667 2.02e-83 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
HEGIFEPM_02669 7.72e-57 yabO - - J - - - S4 domain protein
HEGIFEPM_02670 0.0 yabM - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
HEGIFEPM_02671 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HEGIFEPM_02672 8.29e-129 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HEGIFEPM_02673 2.79e-226 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HEGIFEPM_02674 0.0 - - - S - - - Putative peptidoglycan binding domain
HEGIFEPM_02675 4.87e-148 - - - S - - - (CBS) domain
HEGIFEPM_02676 1.3e-110 queT - - S - - - QueT transporter
HEGIFEPM_02677 2.63e-241 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HEGIFEPM_02678 1.9e-277 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine
HEGIFEPM_02679 2.36e-166 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
HEGIFEPM_02680 3.39e-294 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HEGIFEPM_02681 3.61e-244 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HEGIFEPM_02682 1.3e-105 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
HEGIFEPM_02683 3.58e-122 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
HEGIFEPM_02684 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
HEGIFEPM_02685 2.02e-171 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
HEGIFEPM_02686 3.03e-202 - - - U ko:K02050 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HEGIFEPM_02687 1.37e-248 - - - P ko:K02051 - ko00000,ko00002,ko02000 ABC transporter, substratebinding protein
HEGIFEPM_02688 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
HEGIFEPM_02689 4.28e-84 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
HEGIFEPM_02690 5e-275 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HEGIFEPM_02691 9.32e-81 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HEGIFEPM_02692 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HEGIFEPM_02693 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HEGIFEPM_02694 1.84e-189 - - - - - - - -
HEGIFEPM_02695 9.24e-194 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
HEGIFEPM_02696 5.35e-121 lemA - - S ko:K03744 - ko00000 LemA family
HEGIFEPM_02697 3.14e-164 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
HEGIFEPM_02698 2.57e-274 - - - J - - - translation release factor activity
HEGIFEPM_02699 1.91e-55 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
HEGIFEPM_02700 1.79e-305 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HEGIFEPM_02701 2.08e-302 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HEGIFEPM_02702 4.01e-36 - - - - - - - -
HEGIFEPM_02703 6.59e-170 - - - S - - - YheO-like PAS domain
HEGIFEPM_02704 2.81e-202 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HEGIFEPM_02705 7.51e-159 sdhB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
HEGIFEPM_02706 2.28e-290 sdaC - - E ko:K03837 - ko00000,ko02000 amino acid
HEGIFEPM_02707 5.84e-312 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HEGIFEPM_02708 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HEGIFEPM_02709 2.96e-89 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HEGIFEPM_02710 2.87e-101 ywiB - - S - - - Domain of unknown function (DUF1934)
HEGIFEPM_02711 4.97e-197 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 biotin lipoate A B protein ligase
HEGIFEPM_02712 0.0 ywfO - - S ko:K06885 - ko00000 HD domain protein
HEGIFEPM_02713 1.45e-191 yxeH - - S - - - hydrolase
HEGIFEPM_02714 0.0 - - - L ko:K07487 - ko00000 Transposase
HEGIFEPM_02715 8.69e-179 - - - - - - - -
HEGIFEPM_02716 1.15e-235 - - - S - - - DUF218 domain
HEGIFEPM_02717 5.41e-227 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HEGIFEPM_02718 3.16e-193 bla1 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
HEGIFEPM_02719 3.28e-298 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HEGIFEPM_02720 1.96e-189 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
HEGIFEPM_02721 6.39e-169 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
HEGIFEPM_02722 8.05e-166 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HEGIFEPM_02723 1.9e-230 - - - S ko:K06889 - ko00000 Prolyl oligopeptidase family
HEGIFEPM_02724 2.26e-209 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HEGIFEPM_02725 6.87e-50 veg - - S - - - Biofilm formation stimulator VEG
HEGIFEPM_02726 2.1e-151 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HEGIFEPM_02727 5.87e-39 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HEGIFEPM_02728 1.02e-55 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HEGIFEPM_02729 1.63e-187 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
HEGIFEPM_02730 4.08e-270 - - - EGP ko:K02030 - ko00000,ko00002,ko02000 Drug resistance transporter Bcr CflA subfamily
HEGIFEPM_02731 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HEGIFEPM_02732 4.64e-92 - - - F - - - DNA mismatch repair protein MutT
HEGIFEPM_02733 1.12e-205 yunF - - F - - - Protein of unknown function DUF72
HEGIFEPM_02734 8.73e-171 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
HEGIFEPM_02735 4.65e-229 - - - - - - - -
HEGIFEPM_02736 1.37e-290 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
HEGIFEPM_02737 1.36e-214 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
HEGIFEPM_02738 5.08e-194 - - - S - - - Psort location Cytoplasmic, score
HEGIFEPM_02739 8.64e-263 - - - - - - - -
HEGIFEPM_02740 5.93e-244 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HEGIFEPM_02741 9.75e-175 yecA - - K - - - Helix-turn-helix domain, rpiR family
HEGIFEPM_02742 6.97e-209 - - - GK - - - ROK family
HEGIFEPM_02743 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HEGIFEPM_02744 0.0 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEGIFEPM_02745 3.55e-99 - - - S - - - Domain of unknown function (DUF3284)
HEGIFEPM_02746 9.68e-34 - - - - - - - -
HEGIFEPM_02747 0.0 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEGIFEPM_02748 2.69e-166 - - - K - - - UbiC transcription regulator-associated domain protein
HEGIFEPM_02749 8.19e-244 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HEGIFEPM_02750 5.63e-179 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
HEGIFEPM_02751 0.0 - - - L - - - DNA helicase
HEGIFEPM_02752 4.23e-64 axe - - K ko:K21498 - ko00000,ko02048 Helix-turn-helix XRE-family like proteins
HEGIFEPM_02753 3.12e-48 - - - S ko:K07334 - ko00000,ko02048 RelE-like toxin of type II toxin-antitoxin system HigB
HEGIFEPM_02754 3.9e-146 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HEGIFEPM_02755 1.25e-141 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
HEGIFEPM_02756 2.3e-151 plnU - - S ko:K07052 - ko00000 CAAX protease self-immunity
HEGIFEPM_02757 8.7e-139 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HEGIFEPM_02758 3.36e-306 mesE - - M ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 Transport protein ComB
HEGIFEPM_02759 0.0 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HEGIFEPM_02760 8.82e-32 - - - - - - - -
HEGIFEPM_02761 7.89e-31 plnF - - - - - - -
HEGIFEPM_02762 1.64e-166 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HEGIFEPM_02763 2.04e-171 plnD - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
HEGIFEPM_02764 8.37e-151 sppR - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
HEGIFEPM_02765 9.65e-291 plnB 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
HEGIFEPM_02766 1.9e-25 plnA - - - - - - -
HEGIFEPM_02767 1.22e-36 - - - - - - - -
HEGIFEPM_02768 2.08e-160 plnP - - S - - - CAAX protease self-immunity
HEGIFEPM_02769 3.68e-74 - - - M - - - Glycosyl transferase family 2
HEGIFEPM_02770 2.26e-155 - - - M - - - Glycosyl transferase family 2
HEGIFEPM_02772 1.66e-38 - - - - - - - -
HEGIFEPM_02773 8.53e-34 plnJ - - - - - - -
HEGIFEPM_02774 3.29e-32 plnK - - - - - - -
HEGIFEPM_02775 9.76e-153 - - - - - - - -
HEGIFEPM_02776 6.24e-25 plnR - - - - - - -
HEGIFEPM_02777 7.81e-42 - - - - - - - -
HEGIFEPM_02779 8.8e-265 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HEGIFEPM_02780 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HEGIFEPM_02781 8.38e-192 - - - S - - - hydrolase
HEGIFEPM_02782 2.35e-212 - - - K - - - Transcriptional regulator
HEGIFEPM_02783 4.15e-188 - 3.1.3.102, 3.1.3.104, 3.1.3.23 - G ko:K07757,ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
HEGIFEPM_02784 1.48e-87 - - - EGP - - - Transporter, major facilitator family protein
HEGIFEPM_02785 4.78e-139 - - - EGP - - - Transporter, major facilitator family protein
HEGIFEPM_02786 9.2e-154 lacA 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
HEGIFEPM_02787 2.25e-52 - - - - - - - -
HEGIFEPM_02788 1.51e-17 - - - L - - - LXG domain of WXG superfamily
HEGIFEPM_02789 5.12e-92 - - - S - - - Immunity protein 63
HEGIFEPM_02790 2.05e-90 - - - - - - - -
HEGIFEPM_02791 5.52e-64 - - - U - - - nuclease activity
HEGIFEPM_02792 8.53e-28 - - - - - - - -
HEGIFEPM_02793 3.31e-52 - - - - - - - -
HEGIFEPM_02794 5.89e-131 - - - S - - - ankyrin repeats
HEGIFEPM_02795 1.24e-11 - - - S - - - Immunity protein 22
HEGIFEPM_02796 2.22e-229 - - - - - - - -
HEGIFEPM_02798 2.85e-53 - - - - - - - -
HEGIFEPM_02799 7.13e-54 - - - - - - - -
HEGIFEPM_02800 1.39e-87 - - - M - - - dTDP-4-dehydrorhamnose reductase activity
HEGIFEPM_02801 0.0 - - - M - - - domain protein
HEGIFEPM_02802 2.5e-173 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HEGIFEPM_02803 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 C-terminal domain of alpha-glycerophosphate oxidase
HEGIFEPM_02804 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HEGIFEPM_02805 0.0 gshR 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulphide oxidoreductase
HEGIFEPM_02806 2.7e-230 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HEGIFEPM_02807 0.0 proWX - - EM ko:K05845,ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HEGIFEPM_02808 1.94e-100 - 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA-DNA hybrid ribonuclease activity
HEGIFEPM_02809 1.11e-53 yneD - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HEGIFEPM_02810 3.02e-126 yneD - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HEGIFEPM_02811 8.62e-223 rihA 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
HEGIFEPM_02812 2.43e-103 accB3 - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HEGIFEPM_02813 2.16e-103 - - - - - - - -
HEGIFEPM_02814 5.89e-108 - - - K - - - Winged helix-turn-helix transcription repressor, HrcA DNA-binding
HEGIFEPM_02815 1.61e-294 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
HEGIFEPM_02816 1.31e-124 yxkA - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
HEGIFEPM_02817 5.34e-72 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
HEGIFEPM_02818 0.0 sufI - - Q - - - Multicopper oxidase
HEGIFEPM_02819 7.16e-155 rpiA2 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HEGIFEPM_02820 1.05e-132 zmp1 - - O - - - Zinc-dependent metalloprotease
HEGIFEPM_02821 8.95e-60 - - - - - - - -
HEGIFEPM_02822 1.95e-204 hicD1 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
HEGIFEPM_02823 1.05e-308 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
HEGIFEPM_02824 0.0 - - - P - - - Major Facilitator Superfamily
HEGIFEPM_02825 2.39e-121 - - - K - - - Transcriptional regulator PadR-like family
HEGIFEPM_02826 2.76e-59 - - - - - - - -
HEGIFEPM_02827 9.42e-258 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HEGIFEPM_02828 8.13e-199 tagG - - U ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
HEGIFEPM_02829 6.39e-280 - - - - - - - -
HEGIFEPM_02830 6.62e-286 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HEGIFEPM_02831 1.4e-81 - - - S - - - CHY zinc finger
HEGIFEPM_02832 1.49e-227 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HEGIFEPM_02833 1.54e-123 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
HEGIFEPM_02834 6.4e-54 - - - - - - - -
HEGIFEPM_02835 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HEGIFEPM_02836 7.28e-42 - - - - - - - -
HEGIFEPM_02837 1.43e-170 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
HEGIFEPM_02838 2.36e-305 xylP1 - - G - - - MFS/sugar transport protein
HEGIFEPM_02840 8.16e-207 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
HEGIFEPM_02841 0.0 acdH 1.1.1.1, 1.2.1.10, 1.2.1.87 - C ko:K04072,ko:K13922 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Aldehyde dehydrogenase family
HEGIFEPM_02842 1.08e-243 - - - - - - - -
HEGIFEPM_02843 1.85e-208 - - - V ko:K01990,ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HEGIFEPM_02844 5.05e-79 - - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
HEGIFEPM_02845 2.06e-30 - - - - - - - -
HEGIFEPM_02846 2.14e-117 - - - K - - - acetyltransferase
HEGIFEPM_02847 1.88e-111 - - - K - - - GNAT family
HEGIFEPM_02848 8.08e-110 - - - S - - - ASCH
HEGIFEPM_02849 1.5e-124 - - - K - - - Cupin domain
HEGIFEPM_02850 1.46e-262 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HEGIFEPM_02851 9e-190 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HEGIFEPM_02852 9.24e-180 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HEGIFEPM_02853 5.3e-265 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HEGIFEPM_02854 1.86e-31 - - - U - - - Preprotein translocase subunit SecB
HEGIFEPM_02855 1.04e-35 - - - - - - - -
HEGIFEPM_02857 6.01e-51 - - - - - - - -
HEGIFEPM_02858 9.59e-288 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HEGIFEPM_02859 1.24e-99 - - - K - - - Transcriptional regulator
HEGIFEPM_02860 9.81e-33 - - - S ko:K02348 - ko00000 GNAT family
HEGIFEPM_02861 3.74e-284 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HEGIFEPM_02862 2.03e-75 - - - - - - - -
HEGIFEPM_02863 0.0 uvrB3 3.1.12.1 - KL ko:K07464 - ko00000,ko01000,ko02048 DEAD_2
HEGIFEPM_02864 6.88e-170 - - - - - - - -
HEGIFEPM_02865 3.02e-227 - - - - - - - -
HEGIFEPM_02866 4.2e-88 gcsH1 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Glycine cleavage H-protein
HEGIFEPM_02867 1.43e-82 - - - M - - - LysM domain protein
HEGIFEPM_02868 7.98e-80 - - - M - - - Lysin motif
HEGIFEPM_02869 4.75e-157 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HEGIFEPM_02870 1.13e-171 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
HEGIFEPM_02871 4.87e-156 vex2 - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
HEGIFEPM_02872 3.71e-295 vex3 - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
HEGIFEPM_02873 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
HEGIFEPM_02874 1.61e-136 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
HEGIFEPM_02875 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
HEGIFEPM_02876 1.17e-135 - - - K - - - transcriptional regulator
HEGIFEPM_02877 2.04e-158 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
HEGIFEPM_02878 1.49e-63 - - - - - - - -
HEGIFEPM_02879 0.0 loxD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
HEGIFEPM_02880 7.18e-236 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HEGIFEPM_02881 2.87e-56 - - - - - - - -
HEGIFEPM_02882 3.35e-75 - - - - - - - -
HEGIFEPM_02883 6.86e-311 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEGIFEPM_02884 1.96e-167 yidA - - K - - - Helix-turn-helix domain, rpiR family
HEGIFEPM_02885 2.42e-65 - - - - - - - -
HEGIFEPM_02886 1.56e-164 rrp2 - - K - - - Transcriptional regulatory protein, C terminal
HEGIFEPM_02887 9.08e-317 hpk2 - - T - - - Histidine kinase
HEGIFEPM_02888 2.2e-86 - - - K - - - helix_turn_helix, mercury resistance
HEGIFEPM_02889 0.0 ydiC - - EGP - - - Major Facilitator
HEGIFEPM_02890 1.55e-55 - - - - - - - -
HEGIFEPM_02891 2.92e-57 - - - - - - - -
HEGIFEPM_02892 1.15e-152 - - - - - - - -
HEGIFEPM_02893 5.71e-301 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HEGIFEPM_02894 1.05e-155 - - - K - - - Bacterial regulatory proteins, tetR family
HEGIFEPM_02895 8.9e-96 ywnA - - K - - - Transcriptional regulator
HEGIFEPM_02896 9.53e-93 - - - - - - - -
HEGIFEPM_02897 2.01e-96 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HEGIFEPM_02898 2.51e-20 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HEGIFEPM_02899 2.6e-185 - - - - - - - -
HEGIFEPM_02900 0.0 pts5ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
HEGIFEPM_02901 0.0 pts4ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HEGIFEPM_02902 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
HEGIFEPM_02903 1.68e-166 treR - - K ko:K03486 - ko00000,ko03000 UTRA
HEGIFEPM_02904 2.21e-56 - - - - - - - -
HEGIFEPM_02905 7.55e-58 - - - S - - - Protein of unknown function (DUF2089)
HEGIFEPM_02906 1.27e-181 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
HEGIFEPM_02907 6.72e-203 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
HEGIFEPM_02908 2.91e-201 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HEGIFEPM_02909 4.75e-267 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HEGIFEPM_02910 1.5e-124 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Bacterial transferase hexapeptide (six repeats)
HEGIFEPM_02911 2.02e-245 - 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 pfkB family carbohydrate kinase
HEGIFEPM_02912 1.22e-166 - 4.1.2.14 - S ko:K17463 ko00030,ko01100,ko01120,map00030,map01100,map01120 ko00000,ko00001,ko00002,ko01000 KDGP aldolase
HEGIFEPM_02913 5.06e-259 selA 2.9.1.1 - H ko:K01042 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko01000 L-seryl-tRNA selenium transferase
HEGIFEPM_02914 3.63e-271 dho 3.5.2.3 - S ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Amidohydrolase family
HEGIFEPM_02915 7.59e-269 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
HEGIFEPM_02916 6.14e-53 - - - - - - - -
HEGIFEPM_02917 4.08e-291 pts3C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEGIFEPM_02918 1.89e-159 - - - K - - - helix_turn_helix gluconate operon transcriptional repressor
HEGIFEPM_02919 2.21e-127 - - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
HEGIFEPM_02920 0.0 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
HEGIFEPM_02921 2.41e-106 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
HEGIFEPM_02922 2.98e-90 - - - - - - - -
HEGIFEPM_02923 1.22e-125 - - - - - - - -
HEGIFEPM_02924 7.19e-68 - - - - - - - -
HEGIFEPM_02925 1.96e-75 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
HEGIFEPM_02926 1.21e-111 - - - - - - - -
HEGIFEPM_02927 5.27e-282 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
HEGIFEPM_02928 5.33e-103 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEGIFEPM_02929 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 Mga helix-turn-helix domain
HEGIFEPM_02930 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HEGIFEPM_02931 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HEGIFEPM_02933 3.16e-170 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HEGIFEPM_02934 1.2e-91 - - - - - - - -
HEGIFEPM_02935 1.28e-102 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HEGIFEPM_02936 5.3e-202 dkgB - - S - - - reductase
HEGIFEPM_02937 2.62e-116 gpo 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
HEGIFEPM_02938 1.43e-131 - - - S ko:K16925 - ko00000,ko00002,ko02000 ABC transporter permease
HEGIFEPM_02939 0.0 - - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HEGIFEPM_02940 2.13e-150 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
HEGIFEPM_02941 0.0 - - - S ko:K18231,ko:K19349 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ATPases associated with a variety of cellular activities
HEGIFEPM_02942 5.66e-74 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HEGIFEPM_02943 3.18e-77 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HEGIFEPM_02944 3.81e-18 - - - - - - - -
HEGIFEPM_02945 2.6e-278 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HEGIFEPM_02946 3.59e-207 fbpA - - K - - - Domain of unknown function (DUF814)
HEGIFEPM_02947 4.69e-79 - - - S - - - Domain of unknown function (DU1801)
HEGIFEPM_02948 6.33e-46 - - - - - - - -
HEGIFEPM_02949 4.12e-228 yghZ - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
HEGIFEPM_02950 6.7e-148 pgm1 - - G - - - phosphoglycerate mutase
HEGIFEPM_02951 1.24e-259 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HEGIFEPM_02952 1.45e-278 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEGIFEPM_02953 9.25e-103 yiaC - - K ko:K03826 - ko00000,ko01000 Acetyltransferase (GNAT) domain
HEGIFEPM_02954 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HEGIFEPM_02955 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HEGIFEPM_02956 1.03e-201 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
HEGIFEPM_02958 0.0 - - - M - - - domain protein
HEGIFEPM_02959 5.99e-213 mleR - - K - - - LysR substrate binding domain
HEGIFEPM_02960 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
HEGIFEPM_02961 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
HEGIFEPM_02962 1.16e-210 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
HEGIFEPM_02963 0.0 - 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
HEGIFEPM_02964 3.84e-99 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
HEGIFEPM_02965 8.78e-106 scrR - - K ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HEGIFEPM_02966 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
HEGIFEPM_02967 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HEGIFEPM_02968 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
HEGIFEPM_02969 1.54e-216 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
HEGIFEPM_02970 8.23e-61 ygbF - - S - - - Sugar efflux transporter for intercellular exchange
HEGIFEPM_02971 0.0 - 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Glycosyl hydrolase family 85
HEGIFEPM_02972 2.4e-170 - 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Glycosyl hydrolase family 85
HEGIFEPM_02973 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
HEGIFEPM_02974 2.44e-267 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HEGIFEPM_02975 0.0 malS 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Glycogen debranching enzyme, glucanotransferase domain
HEGIFEPM_02976 1.75e-191 malA - - S - - - maltodextrose utilization protein MalA
HEGIFEPM_02977 2.83e-206 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HEGIFEPM_02978 3.74e-302 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HEGIFEPM_02979 4.69e-299 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HEGIFEPM_02980 0.0 malA1 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
HEGIFEPM_02981 1.83e-231 yvdE - - K - - - helix_turn _helix lactose operon repressor
HEGIFEPM_02982 2.65e-245 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
HEGIFEPM_02983 4.67e-171 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HEGIFEPM_02984 6.76e-75 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 PTS system fructose IIA component
HEGIFEPM_02985 2.75e-131 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
HEGIFEPM_02986 3.88e-239 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
HEGIFEPM_02987 2.35e-243 dhaK2 2.7.1.28, 2.7.1.29, 4.6.1.15 - G ko:K00863 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 ko00000,ko00001,ko00002,ko01000 Dak1 domain
HEGIFEPM_02988 1.85e-121 XK27_02085 - - K - - - Bacterial regulatory proteins, tetR family
HEGIFEPM_02990 2.04e-99 - - - T - - - ECF transporter, substrate-specific component
HEGIFEPM_02991 0.0 etfA 1.3.1.108 - C ko:K03522,ko:K22432 - ko00000,ko01000,ko04147 Electron transfer flavoprotein FAD-binding domain
HEGIFEPM_02992 9.77e-152 - - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
HEGIFEPM_02993 0.0 - - - M ko:K01992 - ko00000,ko00002,ko02000 Exporter of polyketide antibiotics
HEGIFEPM_02994 1.73e-217 ybhF_1 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HEGIFEPM_02995 7.14e-185 dhrS4 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Oxidoreductase, short chain dehydrogenase reductase family protein
HEGIFEPM_02996 3.37e-115 - - - - - - - -
HEGIFEPM_02997 7.76e-192 - - - - - - - -
HEGIFEPM_02998 3.67e-181 - - - - - - - -
HEGIFEPM_02999 4.14e-72 - - - K - - - Transcriptional regulator PadR-like family
HEGIFEPM_03000 4.37e-167 - - - K ko:K03492 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
HEGIFEPM_03002 5.18e-128 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
HEGIFEPM_03003 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HEGIFEPM_03004 7.71e-192 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
HEGIFEPM_03005 6.22e-266 - - - C - - - Oxidoreductase
HEGIFEPM_03006 0.0 - - - - - - - -
HEGIFEPM_03007 1.83e-109 - - - - - - - -
HEGIFEPM_03008 0.0 l1n 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
HEGIFEPM_03009 4.54e-105 - - - F - - - Nucleoside 2-deoxyribosyltransferase like
HEGIFEPM_03010 8.21e-213 - 1.1.1.65 - C ko:K05275 ko00750,ko01100,ko01120,map00750,map01100,map01120 ko00000,ko00001,ko01000 Aldo keto reductase
HEGIFEPM_03011 7.24e-203 morA - - S - - - reductase
HEGIFEPM_03013 2.79e-274 yycB - - P ko:K03449 - ko00000,ko02000 Transporter, major facilitator family protein
HEGIFEPM_03014 7.71e-66 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HEGIFEPM_03015 2.19e-289 - - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
HEGIFEPM_03016 1.1e-93 hsp1 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HEGIFEPM_03017 1.27e-98 - - - K - - - Transcriptional regulator
HEGIFEPM_03018 5.13e-144 azo1 1.5.1.36, 1.7.1.6 - S ko:K03206,ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
HEGIFEPM_03019 2.92e-38 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
HEGIFEPM_03020 8.08e-185 - - - F - - - Phosphorylase superfamily
HEGIFEPM_03021 0.0 pacL1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
HEGIFEPM_03022 1.41e-126 - - - S - - - CRISPR-associated protein (Cas_Csn2)
HEGIFEPM_03023 1.98e-64 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HEGIFEPM_03024 1.85e-168 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HEGIFEPM_03025 1.61e-10 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HEGIFEPM_03026 0.0 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HEGIFEPM_03027 8.69e-184 - - - I - - - Alpha/beta hydrolase family
HEGIFEPM_03028 4.68e-146 - - - - - - - -
HEGIFEPM_03029 1.16e-35 yifK - - E ko:K03293 - ko00000 Amino acid permease
HEGIFEPM_03030 3.55e-109 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
HEGIFEPM_03031 0.0 - - - L - - - HIRAN domain
HEGIFEPM_03032 1.02e-175 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
HEGIFEPM_03033 3.56e-262 thiP - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
HEGIFEPM_03034 2.57e-141 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HEGIFEPM_03035 8.33e-189 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HEGIFEPM_03036 1.08e-174 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HEGIFEPM_03037 1.95e-224 - - - C - - - Zinc-binding dehydrogenase
HEGIFEPM_03038 6.38e-194 larE - - S ko:K06864 - ko00000 NAD synthase
HEGIFEPM_03039 2.4e-170 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HEGIFEPM_03040 6.32e-99 larC2 4.99.1.12 - S ko:K09121 - ko00000,ko01000 Protein of unknown function DUF111
HEGIFEPM_03041 2.03e-179 larC 4.99.1.12 - S ko:K09121 - ko00000,ko01000 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HEGIFEPM_03042 1.08e-161 larB - - S ko:K06898 - ko00000 AIR carboxylase
HEGIFEPM_03043 7.9e-306 larA 5.1.2.1 - S ko:K22373 ko00620,map00620 ko00000,ko00001,ko01000 Domain of unknown function (DUF2088)
HEGIFEPM_03044 1.39e-156 rcfB - - K - - - Crp-like helix-turn-helix domain
HEGIFEPM_03045 1.84e-235 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PDGLE domain
HEGIFEPM_03046 1.14e-190 - - - P ko:K02008 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
HEGIFEPM_03047 7.11e-165 - - - P ko:K02006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HEGIFEPM_03048 1.67e-54 - - - - - - - -
HEGIFEPM_03049 2.69e-182 ant1 2.7.7.47 - H ko:K00984 - ko00000,ko01000,ko01504 Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
HEGIFEPM_03050 6.76e-05 - - - - - - - -
HEGIFEPM_03051 4.85e-180 - - - - - - - -
HEGIFEPM_03052 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
HEGIFEPM_03053 2.38e-99 - - - - - - - -
HEGIFEPM_03054 9.06e-180 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
HEGIFEPM_03055 3.36e-215 pepI 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
HEGIFEPM_03056 5.98e-302 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
HEGIFEPM_03057 1.02e-63 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HEGIFEPM_03058 1.77e-236 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
HEGIFEPM_03059 5.69e-162 - - - S - - - DJ-1/PfpI family
HEGIFEPM_03060 7.65e-121 yfbM - - K - - - FR47-like protein
HEGIFEPM_03061 1.56e-197 - - - EG - - - EamA-like transporter family
HEGIFEPM_03062 2.44e-105 - - - S - - - Protein of unknown function
HEGIFEPM_03063 2.96e-38 - - - S - - - Protein of unknown function
HEGIFEPM_03064 0.0 fusA1 - - J - - - elongation factor G
HEGIFEPM_03065 6.65e-152 azoR - - C ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HEGIFEPM_03066 1.88e-216 - - - K - - - WYL domain
HEGIFEPM_03067 1.25e-164 - - - F - - - glutamine amidotransferase
HEGIFEPM_03068 1.65e-106 - - - S - - - ASCH
HEGIFEPM_03069 0.0 hpaH 1.14.14.8, 1.14.14.9 - Q ko:K00483,ko:K16901 ko00350,ko00380,ko01120,ko01220,map00350,map00380,map01120,map01220 ko00000,ko00001,ko01000 4-hydroxyphenylacetate
HEGIFEPM_03070 6.86e-175 ptp1 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
HEGIFEPM_03071 0.0 - - - S - - - Putative threonine/serine exporter
HEGIFEPM_03072 9.29e-250 pva1 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HEGIFEPM_03073 3.83e-155 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
HEGIFEPM_03075 0.0 - - - QT - - - PucR C-terminal helix-turn-helix domain
HEGIFEPM_03076 5.07e-157 ydgI - - C - - - Nitroreductase family
HEGIFEPM_03077 5.74e-204 adc 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
HEGIFEPM_03078 4.06e-211 - - - S - - - KR domain
HEGIFEPM_03079 4.48e-98 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HEGIFEPM_03080 2.49e-95 - - - C - - - FMN binding
HEGIFEPM_03081 1.46e-204 - - - K - - - LysR family
HEGIFEPM_03082 0.0 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
HEGIFEPM_03083 0.0 - - - C - - - FMN_bind
HEGIFEPM_03084 1.57e-150 - - - S - - - Elongation factor G-binding protein, N-terminal
HEGIFEPM_03085 4.95e-86 - 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 6-pyruvoyl tetrahydropterin synthase
HEGIFEPM_03086 8.12e-158 pnb - - C - - - nitroreductase
HEGIFEPM_03087 5.97e-157 ung2 - - L - - - Uracil-DNA glycosylase
HEGIFEPM_03088 0.0 - - - C - - - Belongs to the aldehyde dehydrogenase family
HEGIFEPM_03089 3.46e-124 - - - K - - - Bacterial regulatory proteins, tetR family
HEGIFEPM_03090 6.08e-107 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HEGIFEPM_03091 1.5e-253 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
HEGIFEPM_03092 1.71e-200 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
HEGIFEPM_03093 1.44e-194 yycI - - S - - - YycH protein
HEGIFEPM_03094 5.88e-312 yycH - - S - - - YycH protein
HEGIFEPM_03095 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HEGIFEPM_03096 4.31e-167 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
HEGIFEPM_03098 6.37e-49 - - - - - - - -
HEGIFEPM_03099 1.47e-41 cspA - - K ko:K03704 - ko00000,ko03000 Cold shock protein
HEGIFEPM_03100 2.09e-100 - - - S - - - Pyridoxamine 5'-phosphate oxidase
HEGIFEPM_03101 0.0 trePP 2.4.1.216, 2.4.1.8 GH65 G ko:K00691,ko:K03731 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycosyl hydrolase family 65 central catalytic domain
HEGIFEPM_03102 2.13e-152 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
HEGIFEPM_03103 2.81e-182 - - - S - - - haloacid dehalogenase-like hydrolase
HEGIFEPM_03105 0.0 malZ 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31 G ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
HEGIFEPM_03106 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HEGIFEPM_03107 0.0 glgA 2.4.1.21 GT5 F ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
HEGIFEPM_03108 3.49e-269 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
HEGIFEPM_03109 5.46e-281 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HEGIFEPM_03110 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HEGIFEPM_03112 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HEGIFEPM_03114 2.67e-291 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HEGIFEPM_03115 9e-184 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HEGIFEPM_03116 4.96e-289 yttB - - EGP - - - Major Facilitator
HEGIFEPM_03117 8.77e-317 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
HEGIFEPM_03118 1.52e-92 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
HEGIFEPM_03119 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
HEGIFEPM_03120 2.69e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HEGIFEPM_03121 1.68e-108 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HEGIFEPM_03122 5.95e-65 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
HEGIFEPM_03123 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HEGIFEPM_03124 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HEGIFEPM_03125 7.24e-263 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HEGIFEPM_03126 3.82e-51 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
HEGIFEPM_03127 8.19e-267 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)