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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
MDKIOEFL_00001	2.21e-42	csfB	-	-	S	-	-	-	Inhibitor of sigma-G Gin
MDKIOEFL_00002	3.15e-131	xpaC	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
MDKIOEFL_00003	3.15e-257	yaaN	-	-	P	-	-	-	Belongs to the TelA family
MDKIOEFL_00004	0.0	yaaO	-	-	E	-	-	-	Orn Lys Arg decarboxylase
MDKIOEFL_00005	1.1e-144	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MDKIOEFL_00006	1.02e-72	yaaQ	-	-	S	-	-	-	protein conserved in bacteria
MDKIOEFL_00007	1.26e-95	yaaR	-	-	S	ko:K09770	-	ko00000	protein conserved in bacteria
MDKIOEFL_00008	2.82e-235	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
MDKIOEFL_00009	6.33e-189	yaaT	-	-	S	-	-	-	stage 0 sporulation protein
MDKIOEFL_00010	1.53e-56	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
MDKIOEFL_00011	3.28e-177	yabB	2.1.1.223	-	S	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Conserved hypothetical protein 95
MDKIOEFL_00012	1.2e-64	yazA	-	-	L	ko:K07461	-	ko00000	endonuclease containing a URI domain
MDKIOEFL_00013	2.95e-207	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MDKIOEFL_00014	1.51e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	COG2002 Regulators of stationary sporulation gene expression
MDKIOEFL_00015	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MDKIOEFL_00016	5.9e-184	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD
MDKIOEFL_00017	4.1e-278	yabE	-	-	T	-	-	-	protein conserved in bacteria
MDKIOEFL_00018	2.03e-125	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MDKIOEFL_00019	5.87e-198	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MDKIOEFL_00020	1.11e-198	yabG	-	-	S	ko:K06436	-	ko00000	peptidase
MDKIOEFL_00021	5.32e-53	veg	-	-	S	-	-	-	protein conserved in bacteria
MDKIOEFL_00022	3.96e-37	sspF	-	-	S	ko:K06423	-	ko00000	DNA topological change
MDKIOEFL_00023	2.34e-207	ispE	2.7.1.148	-	I	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MDKIOEFL_00024	4.66e-196	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
MDKIOEFL_00025	3.45e-83	yabJ	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	translation initiation inhibitor, yjgF family
MDKIOEFL_00026	2.45e-63	spoVG	-	-	D	ko:K06412	-	ko00000	Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
MDKIOEFL_00027	3.66e-309	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MDKIOEFL_00028	1.22e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MDKIOEFL_00029	1.45e-136	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MDKIOEFL_00030	2.03e-135	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MDKIOEFL_00031	6.36e-54	yabK	-	-	S	-	-	-	Peptide ABC transporter permease
MDKIOEFL_00032	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MDKIOEFL_00033	5.88e-121	spoVT	-	-	K	ko:K04769	-	ko00000,ko03000	stage V sporulation protein
MDKIOEFL_00034	0.0	yabM	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MDKIOEFL_00035	0.0	yabN	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
MDKIOEFL_00036	4.22e-50	yabO	-	-	J	-	-	-	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
MDKIOEFL_00037	1.91e-66	yabP	-	-	S	-	-	-	Sporulation protein YabP
MDKIOEFL_00038	1.49e-137	yabQ	-	-	S	-	-	-	spore cortex biosynthesis protein
MDKIOEFL_00039	4.18e-75	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
MDKIOEFL_00040	2.49e-82	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
MDKIOEFL_00043	0.0	spoIIE	3.1.3.16	-	KT	ko:K06382	-	ko00000,ko01000	stage II sporulation protein E
MDKIOEFL_00044	5.61e-168	yabS	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
MDKIOEFL_00045	1.46e-237	yabT	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	serine threonine protein kinase
MDKIOEFL_00046	0.0	tilS	2.4.2.8, 6.3.4.19	-	D	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MDKIOEFL_00047	4.82e-121	hpt	2.4.2.8, 6.3.4.19	-	F	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Belongs to the purine pyrimidine phosphoribosyltransferase family
MDKIOEFL_00048	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MDKIOEFL_00049	6.92e-189	coaX	2.7.1.33	-	F	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MDKIOEFL_00050	1.58e-206	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MDKIOEFL_00051	1.4e-203	yacD	5.2.1.8	-	O	ko:K07533	-	ko00000,ko01000,ko03110	peptidyl-prolyl isomerase
MDKIOEFL_00052	1.54e-217	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
MDKIOEFL_00053	0.0	pabB	2.6.1.85	-	EH	ko:K01665	ko00790,map00790	ko00000,ko00001,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MDKIOEFL_00054	1.72e-136	pabA	2.6.1.85	-	EH	ko:K01664	ko00790,map00790	ko00000,ko00001,ko01000	Anthranilate synthase
MDKIOEFL_00055	6.25e-214	pabC	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	4-amino-4-deoxychorismate lyase
MDKIOEFL_00056	1.11e-203	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MDKIOEFL_00057	3.8e-80	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MDKIOEFL_00058	4.56e-115	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MDKIOEFL_00059	1.81e-41	yazB	-	-	K	-	-	-	transcriptional
MDKIOEFL_00060	1.59e-243	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MDKIOEFL_00061	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
MDKIOEFL_00062	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MDKIOEFL_00063	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MDKIOEFL_00064	1.25e-51	yaaB	-	-	S	-	-	-	Domain of unknown function (DUF370)
MDKIOEFL_00065	4.54e-264	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MDKIOEFL_00066	2.24e-45	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
MDKIOEFL_00067	1.71e-263	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MDKIOEFL_00068	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MDKIOEFL_00069	5.7e-71	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MDKIOEFL_00070	9.29e-179	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MDKIOEFL_00071	1.83e-141	jag	-	-	S	ko:K06346	-	ko00000	single-stranded nucleic acid binding R3H
MDKIOEFL_00072	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MDKIOEFL_00073	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MDKIOEFL_00074	1.68e-166	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
MDKIOEFL_00075	9e-193	noc	-	-	D	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
MDKIOEFL_00076	1.87e-97	-	-	-	S	-	-	-	Bacterial PH domain
MDKIOEFL_00077	4.79e-173	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	COG1192 ATPases involved in chromosome partitioning
MDKIOEFL_00078	3.96e-191	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
MDKIOEFL_00079	4.53e-145	yyaC	-	-	S	-	-	-	Sporulation protein YyaC
MDKIOEFL_00080	5.34e-227	yyaD	-	-	S	-	-	-	Membrane
MDKIOEFL_00081	7.41e-45	yyzM	-	-	S	-	-	-	protein conserved in bacteria
MDKIOEFL_00082	0.0	yyaE	-	-	C	-	-	-	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MDKIOEFL_00083	5.65e-256	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MDKIOEFL_00084	1.01e-61	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
MDKIOEFL_00085	1.81e-103	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MDKIOEFL_00086	4.25e-49	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MDKIOEFL_00087	4.01e-185	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
MDKIOEFL_00088	2.49e-229	ccpB	-	-	K	-	-	-	Transcriptional regulator
MDKIOEFL_00089	1.02e-89	yyaH	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MDKIOEFL_00090	2.2e-128	vatD	2.3.1.28, 2.3.1.79	-	S	ko:K00638,ko:K00661,ko:K18234	-	br01600,ko00000,ko01000,ko01504	Bacterial transferase hexapeptide (six repeats)
MDKIOEFL_00091	0.0	-	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major facilitator superfamily
MDKIOEFL_00092	5.15e-216	yyaK	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MDKIOEFL_00093	0.0	yyaL	-	-	O	ko:K06888	-	ko00000	COG1331 Highly conserved protein containing a thioredoxin domain
MDKIOEFL_00094	1.86e-106	-	-	-	E	-	-	-	Transglutaminase-like superfamily
MDKIOEFL_00096	4.36e-20	-	-	-	L	-	-	-	Recombinase
MDKIOEFL_00099	6.81e-134	yyaP	-	-	H	-	-	-	RibD C-terminal domain
MDKIOEFL_00100	7.13e-84	-	-	-	S	-	-	-	YjbR
MDKIOEFL_00101	9.87e-122	-	-	-	K	ko:K19273	-	ko00000,ko01000,ko01504	Acetyltransferase (GNAT) domain
MDKIOEFL_00102	1.05e-125	yyaS	-	-	S	ko:K07149	-	ko00000	Membrane
MDKIOEFL_00103	1.65e-92	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
MDKIOEFL_00104	4.54e-100	yybA	-	-	K	-	-	-	transcriptional
MDKIOEFL_00105	2.16e-164	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
MDKIOEFL_00106	1.22e-97	yybC	-	-	-	-	-	-	-
MDKIOEFL_00107	2.18e-101	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
MDKIOEFL_00108	1.25e-208	yybE	-	-	K	-	-	-	Transcriptional regulator
MDKIOEFL_00109	1.06e-277	yybF	-	-	EGP	ko:K08224	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MDKIOEFL_00110	3.13e-159	yybG	-	-	S	-	-	-	Pentapeptide repeat-containing protein
MDKIOEFL_00111	2.91e-86	-	-	-	S	-	-	-	SnoaL-like domain
MDKIOEFL_00112	6.85e-182	-	-	-	-	-	-	-	-
MDKIOEFL_00113	2.07e-140	-	-	-	K	-	-	-	TipAS antibiotic-recognition domain
MDKIOEFL_00114	1.01e-307	yybO	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MDKIOEFL_00116	7.84e-91	-	-	-	-	-	-	-	-
MDKIOEFL_00117	5.7e-209	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	Inorganic pyrophosphatase
MDKIOEFL_00118	6.68e-90	yybR	-	-	K	-	-	-	Transcriptional regulator
MDKIOEFL_00119	2.89e-110	cotF	-	-	M	ko:K06329	-	ko00000	Spore coat protein
MDKIOEFL_00121	2.56e-145	yybS	-	-	S	-	-	-	membrane
MDKIOEFL_00122	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
MDKIOEFL_00123	6.45e-95	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
MDKIOEFL_00124	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MDKIOEFL_00125	4.68e-280	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	COG2807 Cyanate permease
MDKIOEFL_00126	1.89e-22	yycC	-	-	K	-	-	-	YycC-like protein
MDKIOEFL_00128	3.48e-40	yycD	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
MDKIOEFL_00129	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
MDKIOEFL_00130	2.71e-98	yycE	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MDKIOEFL_00131	1.29e-314	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MDKIOEFL_00136	1.45e-172	yycF	-	-	T	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MDKIOEFL_00137	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MDKIOEFL_00138	0.0	yycH	-	-	S	-	-	-	protein conserved in bacteria
MDKIOEFL_00139	1.2e-200	yycI	-	-	S	-	-	-	protein conserved in bacteria
MDKIOEFL_00140	4.68e-190	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
MDKIOEFL_00141	2.82e-280	yyxA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MDKIOEFL_00142	0.0	rocR	-	-	KT	ko:K06714	-	ko00000,ko03000	COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
MDKIOEFL_00143	9.68e-293	rocD	2.6.1.13	-	E	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Catalyzes the interconversion of ornithine to glutamate semialdehyde
MDKIOEFL_00144	0.0	rocE	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MDKIOEFL_00145	3.22e-213	rocF	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
MDKIOEFL_00147	4.12e-237	-	-	-	S	-	-	-	aspartate phosphatase
MDKIOEFL_00148	8.71e-110	yycN	-	-	K	-	-	-	Acetyltransferase
MDKIOEFL_00149	6.83e-169	yycO	-	-	S	-	-	-	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MDKIOEFL_00150	1.31e-267	yycP	-	-	-	-	-	-	-
MDKIOEFL_00151	1.92e-42	yycQ	-	-	S	-	-	-	Protein of unknown function (DUF2651)
MDKIOEFL_00153	1.01e-294	yycR	1.1.1.1, 1.1.1.284, 1.2.1.46	-	E	ko:K00121,ko:K00148	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MDKIOEFL_00154	3.31e-89	-	-	-	-	-	-	-	-
MDKIOEFL_00156	5e-106	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MDKIOEFL_00159	1.49e-165	-	-	-	S	-	-	-	AIPR protein
MDKIOEFL_00160	9.2e-24	-	-	-	S	-	-	-	Fusaric acid resistance protein-like
MDKIOEFL_00161	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Firmicute fructose-1,6-bisphosphatase
MDKIOEFL_00162	8.12e-17	-	-	-	-	-	-	-	-
MDKIOEFL_00163	7.8e-237	-	-	-	S	-	-	-	Radical SAM superfamily
MDKIOEFL_00164	3.65e-172	-	-	-	O	ko:K16922	-	ko00000,ko01002	Peptidase M50
MDKIOEFL_00165	8.4e-143	-	-	-	P	ko:K16917	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MDKIOEFL_00166	3.18e-151	-	-	-	S	ko:K16916	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
MDKIOEFL_00167	1.44e-24	-	-	-	-	-	-	-	-
MDKIOEFL_00168	3.37e-160	yydK	-	-	K	ko:K03489	-	ko00000,ko03000	Transcriptional regulator
MDKIOEFL_00169	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MDKIOEFL_00170	1.58e-237	-	-	-	S	-	-	-	Polysaccharide pyruvyl transferase
MDKIOEFL_00171	0.0	ahpF	-	-	O	ko:K03387	-	ko00000,ko01000	Alkyl hydroperoxide reductase
MDKIOEFL_00172	9.33e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Alkyl hydroperoxide reductase
MDKIOEFL_00173	0.0	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MDKIOEFL_00174	1.68e-294	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
MDKIOEFL_00175	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
MDKIOEFL_00176	3.63e-163	gntR	-	-	K	ko:K11476	-	ko00000,ko03000	transcriptional
MDKIOEFL_00177	6.4e-261	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
MDKIOEFL_00178	3.62e-245	-	-	-	GM	ko:K19426	-	ko00000,ko01000	Polysaccharide pyruvyl transferase
MDKIOEFL_00179	5.16e-152	yxaC	-	-	M	-	-	-	effector of murein hydrolase
MDKIOEFL_00180	8.4e-76	-	-	-	S	ko:K06518	-	ko00000,ko02000	LrgA family
MDKIOEFL_00181	6.83e-94	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MDKIOEFL_00182	1.23e-254	yxnA	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
MDKIOEFL_00183	3.22e-129	yxaF	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
MDKIOEFL_00184	1.05e-250	-	1.13.11.24	-	S	ko:K07155	-	ko00000,ko01000	AraC-like ligand binding domain
MDKIOEFL_00185	1.25e-284	-	-	-	P	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
MDKIOEFL_00186	4.03e-99	yxaI	-	-	S	-	-	-	membrane protein domain
MDKIOEFL_00187	3.11e-80	-	-	-	S	-	-	-	Family of unknown function (DUF5391)
MDKIOEFL_00188	8.6e-136	yxaL	-	-	S	-	-	-	PQQ-like domain
MDKIOEFL_00189	2.01e-37	yxaI	-	-	S	-	-	-	membrane protein domain
MDKIOEFL_00190	1.39e-312	aldX	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MDKIOEFL_00191	1.08e-267	yxbF	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MDKIOEFL_00192	4.15e-193	yxbG	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
MDKIOEFL_00194	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Molecular chaperone. Has ATPase activity
MDKIOEFL_00195	1.45e-313	csbC	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MDKIOEFL_00196	9.41e-105	-	-	-	T	-	-	-	HPP family
MDKIOEFL_00197	1.1e-114	-	-	-	S	-	-	-	CGNR zinc finger
MDKIOEFL_00198	1.01e-64	yxcD	-	-	S	-	-	-	Protein of unknown function (DUF2653)
MDKIOEFL_00200	1.43e-223	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
MDKIOEFL_00201	1.56e-177	iolR	-	-	K	ko:K06608,ko:K11534	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
MDKIOEFL_00202	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MDKIOEFL_00203	1.41e-199	iolB	5.3.1.30	-	G	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
MDKIOEFL_00204	1.75e-227	iolC	2.7.1.92	-	G	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
MDKIOEFL_00205	0.0	iolD	3.7.1.22	-	E	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
MDKIOEFL_00206	4.99e-222	iolE	4.2.1.44	-	G	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
MDKIOEFL_00207	3.44e-297	iolF	-	-	EGP	ko:K06610	-	ko00000,ko02000	Major facilitator superfamily
MDKIOEFL_00208	4.44e-251	iolG	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
MDKIOEFL_00209	6.24e-212	iolH	-	-	G	ko:K06605	-	ko00000	Xylose isomerase-like TIM barrel
MDKIOEFL_00210	4.62e-193	iolI	5.3.99.11	-	G	ko:K06606	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
MDKIOEFL_00211	4.69e-203	fbaA	4.1.2.13, 4.1.2.29	-	F	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
MDKIOEFL_00212	2.8e-160	yxdJ	-	-	T	ko:K02483,ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MDKIOEFL_00213	2.7e-231	yxdK	2.7.13.3	-	T	ko:K11633	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MDKIOEFL_00214	4.46e-180	yxdL	-	-	V	ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MDKIOEFL_00215	0.0	yxdM	-	-	V	ko:K11636	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
MDKIOEFL_00216	4.9e-76	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
MDKIOEFL_00217	4.99e-225	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MDKIOEFL_00218	9.65e-91	-	-	-	-	-	-	-	-
MDKIOEFL_00219	7.57e-28	yxeD	-	-	-	-	-	-	-
MDKIOEFL_00220	7.32e-42	yxeE	-	-	-	-	-	-	-
MDKIOEFL_00223	2.71e-192	yxeH	-	-	S	-	-	-	hydrolases of the HAD superfamily
MDKIOEFL_00224	6.15e-234	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
MDKIOEFL_00225	0.0	yxeK	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MDKIOEFL_00226	1.54e-121	yxeL	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MDKIOEFL_00227	1.44e-184	yxeM	-	-	M	ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
MDKIOEFL_00228	3e-148	yxeN	-	-	P	ko:K10009,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
MDKIOEFL_00229	1.67e-171	yxeO	-	-	P	ko:K16960,ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MDKIOEFL_00230	1.95e-270	yxeP	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	hydrolase activity
MDKIOEFL_00231	9.34e-317	yxeQ	-	-	S	-	-	-	MmgE/PrpD family
MDKIOEFL_00232	2.21e-255	eutH	-	-	E	ko:K04023	-	ko00000	Ethanolamine utilisation protein, EutH
MDKIOEFL_00233	4.33e-196	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1206)
MDKIOEFL_00234	4.26e-222	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MDKIOEFL_00235	8.3e-150	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MDKIOEFL_00236	2.72e-263	nupC	-	-	F	ko:K11535	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MDKIOEFL_00237	6.66e-298	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	phosphorylase
MDKIOEFL_00238	0.0	ybgF	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MDKIOEFL_00239	7.71e-228	hutG	3.5.3.8	-	E	ko:K01479	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
MDKIOEFL_00240	4.32e-297	hutI	3.5.2.7	-	Q	ko:K01468	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Imidazolone-5-propionate hydrolase
MDKIOEFL_00241	0.0	hutU	4.2.1.49	-	E	ko:K01712	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MDKIOEFL_00242	0.0	hutH	4.3.1.3	-	E	ko:K01745	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Histidine ammonia-lyase
MDKIOEFL_00243	7.02e-103	hutP	-	-	K	ko:K09683	-	ko00000,ko03000	Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
MDKIOEFL_00244	0.0	yxiA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
MDKIOEFL_00245	5.38e-37	-	-	-	S	-	-	-	Domain of unknown function (DUF5082)
MDKIOEFL_00246	1.33e-52	yxiC	-	-	S	-	-	-	Family of unknown function (DUF5344)
MDKIOEFL_00247	2.99e-275	-	-	-	S	ko:K21493	-	ko00000,ko01000,ko02048	nuclease activity
MDKIOEFL_00248	5.41e-73	-	-	-	-	-	-	-	-
MDKIOEFL_00249	1.37e-53	-	-	-	-	-	-	-	-
MDKIOEFL_00250	6.38e-37	-	-	-	-	-	-	-	-
MDKIOEFL_00251	4.47e-76	-	-	-	-	-	-	-	-
MDKIOEFL_00253	1.6e-53	-	-	-	-	-	-	-	-
MDKIOEFL_00254	6.12e-24	-	-	-	-	-	-	-	-
MDKIOEFL_00255	1.52e-23	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2247)
MDKIOEFL_00256	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MDKIOEFL_00257	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MDKIOEFL_00258	8.5e-95	yxiE	-	-	T	-	-	-	Belongs to the universal stress protein A family
MDKIOEFL_00259	2.74e-158	-	1.14.11.45	-	E	ko:K20418	-	ko00000,ko01000	2OG-Fe dioxygenase
MDKIOEFL_00260	5.76e-162	bacC	1.1.1.385	-	IQ	ko:K19548	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MDKIOEFL_00261	1.7e-209	yxxF	-	-	EG	-	-	-	EamA-like transporter family
MDKIOEFL_00263	3.63e-48	-	-	-	-	-	-	-	-
MDKIOEFL_00264	2.81e-90	yxiG	-	-	-	-	-	-	-
MDKIOEFL_00265	4.73e-175	-	-	-	-	-	-	-	-
MDKIOEFL_00266	2.47e-99	yxiI	-	-	S	-	-	-	Protein of unknown function (DUF2716)
MDKIOEFL_00267	6.49e-55	yxiJ	-	-	S	-	-	-	YxiJ-like protein
MDKIOEFL_00270	5.65e-80	-	-	-	S	-	-	-	Protein of unknown function (DUF2812)
MDKIOEFL_00271	7e-70	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
MDKIOEFL_00272	7.94e-271	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MDKIOEFL_00273	0.0	dbpA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
MDKIOEFL_00274	3.64e-290	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	COG2270 Permeases of the major facilitator superfamily
MDKIOEFL_00275	2.75e-145	-	-	-	-	-	-	-	-
MDKIOEFL_00276	5.66e-193	licT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
MDKIOEFL_00277	1.77e-183	bglS	-	-	M	-	-	-	licheninase activity
MDKIOEFL_00278	4.7e-283	citH	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
MDKIOEFL_00279	0.0	katE	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
MDKIOEFL_00280	2.28e-63	yxiS	-	-	-	-	-	-	-
MDKIOEFL_00281	1.78e-134	-	-	-	T	-	-	-	Domain of unknown function (DUF4163)
MDKIOEFL_00282	2.1e-269	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MDKIOEFL_00283	2.67e-189	yxjB	2.1.1.187	-	Q	ko:K00563	-	ko00000,ko01000,ko03009	Methyltransferase domain
MDKIOEFL_00284	0.0	yxjC	-	-	EG	-	-	-	COG2610 H gluconate symporter and related permeases
MDKIOEFL_00285	5.43e-167	scoA	2.8.3.5	-	I	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MDKIOEFL_00286	5.91e-151	scoB	2.8.3.5	-	I	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MDKIOEFL_00287	1.67e-175	yxjF	1.1.1.30	-	IQ	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
MDKIOEFL_00288	1.81e-274	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
MDKIOEFL_00289	3.53e-276	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
MDKIOEFL_00290	8.27e-111	yxjI	-	-	S	-	-	-	LURP-one-related
MDKIOEFL_00292	2.22e-298	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
MDKIOEFL_00293	3.52e-144	-	-	-	K	ko:K02479	-	ko00000,ko02022	helix_turn_helix, Lux Regulon
MDKIOEFL_00294	4.91e-243	-	-	-	T	-	-	-	Signal transduction histidine kinase
MDKIOEFL_00295	2.68e-100	-	-	-	S	-	-	-	Protein of unknown function (DUF1453)
MDKIOEFL_00296	2.11e-251	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
MDKIOEFL_00297	4.99e-100	yxkC	-	-	S	-	-	-	Domain of unknown function (DUF4352)
MDKIOEFL_00298	2.29e-188	yxkD	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MDKIOEFL_00299	0.0	aldY	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MDKIOEFL_00300	7.85e-210	lrp	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
MDKIOEFL_00301	3.44e-261	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MDKIOEFL_00302	5.28e-199	yxkH	-	-	G	-	-	-	Polysaccharide deacetylase
MDKIOEFL_00304	0.0	-	-	-	O	-	-	-	Peptidase family M48
MDKIOEFL_00305	2.67e-308	cimH	-	-	C	-	-	-	COG3493 Na citrate symporter
MDKIOEFL_00306	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
MDKIOEFL_00307	4.74e-243	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase, subunit II
MDKIOEFL_00308	0.0	cydC	-	-	V	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding
MDKIOEFL_00309	0.0	cydD	-	-	V	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding protein
MDKIOEFL_00310	6.19e-201	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MDKIOEFL_00311	0.0	yxlA	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
MDKIOEFL_00312	9.06e-125	sigY	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MDKIOEFL_00313	1.3e-60	yxlC	-	-	S	-	-	-	Family of unknown function (DUF5345)
MDKIOEFL_00314	1.63e-39	-	-	-	-	-	-	-	-
MDKIOEFL_00315	2.17e-39	yxlE	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
MDKIOEFL_00316	2.45e-212	yxlF	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MDKIOEFL_00317	1.33e-177	yxlG	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MDKIOEFL_00318	8.28e-273	yxlH	-	-	EGP	-	-	-	Major Facilitator Superfamily
MDKIOEFL_00319	0.0	katX	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
MDKIOEFL_00320	3.23e-145	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
MDKIOEFL_00321	8.94e-28	yxzF	-	-	-	-	-	-	-
MDKIOEFL_00322	0.0	licR	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
MDKIOEFL_00323	1.89e-67	licB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	transporter subunit IIB
MDKIOEFL_00324	0.0	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDKIOEFL_00325	1.58e-50	licA	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MDKIOEFL_00326	0.0	licH	3.2.1.86	GT4	G	ko:K01222	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MDKIOEFL_00327	1.07e-263	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
MDKIOEFL_00328	2.91e-178	dltE	-	-	M	ko:K14189	-	ko00000,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
MDKIOEFL_00329	4.09e-294	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MDKIOEFL_00330	6.83e-50	dltC	6.1.1.13	-	IQ	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDKIOEFL_00331	1.14e-297	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	membrane protein involved in D-alanine export
MDKIOEFL_00332	0.0	dltA	6.1.1.13	-	Q	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDKIOEFL_00333	5.1e-213	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
MDKIOEFL_00334	2.52e-149	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	protein conserved in bacteria
MDKIOEFL_00335	2.14e-162	-	-	-	EGP	-	-	-	Permeases of the major facilitator superfamily
MDKIOEFL_00336	7.93e-64	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
MDKIOEFL_00337	5.05e-117	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MDKIOEFL_00338	1.83e-316	ywaD	3.4.11.10, 3.4.11.6	-	S	ko:K19701	-	ko00000,ko01000,ko01002	PA domain
MDKIOEFL_00339	2.59e-296	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MDKIOEFL_00340	1.46e-113	ywaE	-	-	K	-	-	-	Transcriptional regulator
MDKIOEFL_00341	1.17e-156	ywaF	-	-	S	-	-	-	Integral membrane protein
MDKIOEFL_00342	1.87e-216	gspA	-	-	M	-	-	-	General stress
MDKIOEFL_00343	2.6e-195	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
MDKIOEFL_00344	1.45e-312	sacX	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MDKIOEFL_00345	0.0	epr	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MDKIOEFL_00346	4.68e-315	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDKIOEFL_00347	4.15e-160	ywbB	-	-	S	-	-	-	Protein of unknown function (DUF2711)
MDKIOEFL_00348	5.44e-122	-	-	-	N	-	-	-	domain, Protein
MDKIOEFL_00349	5.7e-87	ywbC	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	glyoxalase
MDKIOEFL_00350	4.67e-279	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
MDKIOEFL_00351	6.33e-38	ywbE	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2196)
MDKIOEFL_00352	3.04e-277	ywbF	-	-	EGP	ko:K05820	-	ko00000,ko02000	Nucleoside H+ symporter
MDKIOEFL_00353	1.21e-143	ywbG	-	-	M	-	-	-	effector of murein hydrolase
MDKIOEFL_00354	1.56e-76	ywbH	-	-	S	ko:K06518	-	ko00000,ko02000	Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
MDKIOEFL_00355	2.7e-203	ywbI	-	-	K	-	-	-	Transcriptional regulator
MDKIOEFL_00356	1.32e-184	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MDKIOEFL_00357	4.27e-147	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MDKIOEFL_00358	0.0	-	-	-	P	ko:K07243	-	ko00000,ko02000	COG0672 High-affinity Fe2 Pb2 permease
MDKIOEFL_00359	9.83e-246	ycdO	-	-	P	ko:K07224	-	ko00000,ko02000	periplasmic lipoprotein involved in iron transport
MDKIOEFL_00360	2.65e-309	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Dyp-type peroxidase family protein
MDKIOEFL_00361	1.32e-143	ywbO	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
MDKIOEFL_00362	0.0	ywcA	-	-	S	ko:K14393	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MDKIOEFL_00363	6.1e-64	ywcB	-	-	S	-	-	-	Protein of unknown function, DUF485
MDKIOEFL_00365	3.42e-158	ywcC	-	-	K	-	-	-	transcriptional regulator
MDKIOEFL_00366	3.33e-77	gtcA	-	-	S	-	-	-	GtrA-like protein
MDKIOEFL_00367	4.38e-288	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MDKIOEFL_00368	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
MDKIOEFL_00369	5.11e-49	ydaS	-	-	S	-	-	-	membrane
MDKIOEFL_00370	6.94e-226	qoxA	1.10.3.12	-	C	ko:K02826	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
MDKIOEFL_00371	0.0	qoxB	1.10.3.12	-	C	ko:K02827	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MDKIOEFL_00372	1.2e-144	qoxC	1.10.3.12	-	C	ko:K02828	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
MDKIOEFL_00373	1.12e-83	qoxD	1.10.3.12	-	C	ko:K02829	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
MDKIOEFL_00374	6.61e-52	ywcE	-	-	S	-	-	-	Required for proper spore morphogenesis. Important for spore germination
MDKIOEFL_00375	1.26e-268	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
MDKIOEFL_00376	3.28e-178	nfrA1	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	Oxidoreductase
MDKIOEFL_00377	3.44e-238	ywcH	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MDKIOEFL_00378	0.0	prtS	3.4.21.110, 3.4.21.96	-	O	ko:K01361,ko:K08652,ko:K14647	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MDKIOEFL_00380	1.29e-193	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
MDKIOEFL_00381	6.85e-179	-	-	-	P	ko:K02598	-	ko00000,ko02000	Formate/nitrite transporter
MDKIOEFL_00382	0.0	sacP	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MDKIOEFL_00383	0.0	sacA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
MDKIOEFL_00384	6.19e-39	ywdA	-	-	-	-	-	-	-
MDKIOEFL_00385	1.28e-186	pdxK	2.7.1.35, 2.7.1.49, 2.7.4.7	-	H	ko:K00868,ko:K00941	ko00730,ko00750,ko01100,map00730,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
MDKIOEFL_00386	7.92e-76	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
MDKIOEFL_00387	8.74e-146	ywdD	-	-	-	-	-	-	-
MDKIOEFL_00389	4.68e-192	ywdF	-	-	S	-	-	-	Glycosyltransferase like family 2
MDKIOEFL_00390	9.47e-166	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MDKIOEFL_00391	0.0	ywdH	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MDKIOEFL_00392	2.18e-63	ywdI	-	-	S	-	-	-	Family of unknown function (DUF5327)
MDKIOEFL_00393	1.86e-303	ywdJ	-	-	F	-	-	-	Xanthine uracil
MDKIOEFL_00394	1.59e-78	ywdK	-	-	S	-	-	-	small membrane protein
MDKIOEFL_00395	3.62e-112	gerQ	-	-	S	ko:K06305	-	ko00000	Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
MDKIOEFL_00396	1.15e-186	spsA	-	-	M	-	-	-	Spore Coat
MDKIOEFL_00397	0.0	spsB	-	-	M	-	-	-	Capsule polysaccharide biosynthesis protein
MDKIOEFL_00398	1.07e-283	spsC	2.6.1.102	-	E	ko:K13010	ko00520,map00520	ko00000,ko00001,ko01000,ko01005,ko01007	Belongs to the DegT DnrJ EryC1 family
MDKIOEFL_00399	2.44e-209	spsD	2.3.1.210	-	K	ko:K16704	-	ko00000,ko01000	Spore Coat
MDKIOEFL_00400	4.59e-270	pseI	2.5.1.56, 2.5.1.97	-	M	ko:K01654,ko:K15898	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	acid synthase
MDKIOEFL_00401	8.63e-165	spsF	-	-	M	ko:K07257	-	ko00000	Spore Coat
MDKIOEFL_00402	1.16e-239	spsG	-	-	M	-	-	-	Spore Coat
MDKIOEFL_00403	6.13e-177	spsI	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MDKIOEFL_00404	3.7e-233	spsJ	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MDKIOEFL_00405	3.57e-201	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MDKIOEFL_00406	1.52e-112	spsL	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Spore Coat
MDKIOEFL_00407	6.13e-100	-	-	-	-	-	-	-	-
MDKIOEFL_00408	2.11e-310	rocG	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
MDKIOEFL_00409	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
MDKIOEFL_00410	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
MDKIOEFL_00411	1.77e-316	rocC	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MDKIOEFL_00412	6.3e-274	ywfA	-	-	EGP	-	-	-	-transporter
MDKIOEFL_00413	5.11e-146	bacA	4.1.1.100	-	E	ko:K19546	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
MDKIOEFL_00414	1.24e-175	bacB	5.3.3.19	-	S	ko:K19547	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
MDKIOEFL_00415	1.33e-179	bacC	1.1.1.385	-	IQ	ko:K19548	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MDKIOEFL_00416	0.0	bacD	6.3.2.49	-	F	ko:K13037	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
MDKIOEFL_00417	1.52e-265	bacE	-	-	EGP	ko:K19552	-	ko00000,ko02000	Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
MDKIOEFL_00418	7.09e-294	ywfG	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
MDKIOEFL_00419	1.13e-174	ywfH	-	-	IQ	ko:K19550	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Enoyl-(Acyl carrier protein) reductase
MDKIOEFL_00420	3.43e-187	ywfI	-	-	C	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko01000	May function as heme-dependent peroxidase
MDKIOEFL_00421	1.67e-224	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	In Salmonella this enzyme is required for ethanolamine catabolism
MDKIOEFL_00422	3.73e-209	cysL	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
MDKIOEFL_00423	1.77e-198	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
MDKIOEFL_00424	3.55e-201	ywfM	-	-	EG	ko:K03298	-	ko00000,ko02000	EamA-like transporter family
MDKIOEFL_00425	6.58e-146	rsfA_1	-	-	-	ko:K06314	-	ko00000,ko03000	-
MDKIOEFL_00426	8.55e-49	ywzC	-	-	S	-	-	-	Belongs to the UPF0741 family
MDKIOEFL_00427	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	COG1078 HD superfamily phosphohydrolases
MDKIOEFL_00428	1.47e-115	ywgA	-	-	-	ko:K09388	-	ko00000	-
MDKIOEFL_00429	7.42e-102	yffB	-	-	K	-	-	-	Transcriptional regulator
MDKIOEFL_00430	5.54e-303	mmr	-	-	U	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
MDKIOEFL_00432	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MDKIOEFL_00433	1.76e-94	ywhA	-	-	K	-	-	-	Transcriptional regulator
MDKIOEFL_00434	1.43e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	4-oxalocrotonate tautomerase
MDKIOEFL_00435	3.29e-154	ywhC	-	-	S	-	-	-	Peptidase family M50
MDKIOEFL_00436	2.62e-121	ywhD	-	-	S	-	-	-	YwhD family
MDKIOEFL_00437	0.0	pbpG	2.4.1.129, 3.4.16.4	GT51	M	ko:K21464	ko00550,map00550	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
MDKIOEFL_00438	1.93e-204	speE	2.5.1.16	-	E	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MDKIOEFL_00439	2.1e-215	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
MDKIOEFL_00441	1.4e-74	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MDKIOEFL_00444	1.3e-10	-	-	-	-	-	-	-	-
MDKIOEFL_00447	9.28e-99	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
MDKIOEFL_00448	9.47e-275	ywhK	-	-	CO	-	-	-	amine dehydrogenase activity
MDKIOEFL_00449	9.08e-317	ywhL	-	-	CO	-	-	-	amine dehydrogenase activity
MDKIOEFL_00451	1.09e-313	-	-	-	L	-	-	-	Peptidase, M16
MDKIOEFL_00452	6.93e-276	-	2.7.1.26, 2.7.7.2	-	L	ko:K07263,ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01002	Peptidase, M16
MDKIOEFL_00453	1.14e-295	mgtA	3.6.3.2	-	P	ko:K01531,ko:K16905	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPase, P-type transporting, HAD superfamily, subfamily IC
MDKIOEFL_00454	6.11e-169	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
MDKIOEFL_00456	0.0	-	-	-	C	ko:K22227	-	ko00000	Fe-S oxidoreductases
MDKIOEFL_00457	3.71e-12	-	-	-	S	-	-	-	Bacteriocin subtilosin A
MDKIOEFL_00458	4.64e-96	ywiB	-	-	S	-	-	-	protein conserved in bacteria
MDKIOEFL_00459	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
MDKIOEFL_00460	1.2e-273	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
MDKIOEFL_00461	3.27e-168	fnr	-	-	K	-	-	-	helix_turn_helix, cAMP Regulatory protein
MDKIOEFL_00462	3.71e-179	ywiC	-	-	S	-	-	-	YwiC-like protein
MDKIOEFL_00463	1.44e-109	arfM	-	-	T	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	cyclic nucleotide binding
MDKIOEFL_00464	0.0	narG	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MDKIOEFL_00465	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase, beta
MDKIOEFL_00466	5.36e-120	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase
MDKIOEFL_00467	1.02e-159	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase (gamma
MDKIOEFL_00468	0.0	ywiE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MDKIOEFL_00469	0.0	ywjA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
MDKIOEFL_00470	5.49e-124	ywjB	-	-	H	-	-	-	RibD C-terminal domain
MDKIOEFL_00471	1.32e-57	ywjC	-	-	-	-	-	-	-
MDKIOEFL_00472	2.82e-235	uvsE	-	-	L	ko:K13281	-	ko00000,ko01000	Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
MDKIOEFL_00473	1.59e-285	clsB	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the phospholipase D family. Cardiolipin synthase subfamily
MDKIOEFL_00474	0.0	ywjF	-	-	C	-	-	-	COG0247 Fe-S oxidoreductase
MDKIOEFL_00475	2.98e-269	acdA	-	-	I	-	-	-	acyl-CoA dehydrogenase
MDKIOEFL_00476	1.03e-82	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MDKIOEFL_00477	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MDKIOEFL_00478	9.11e-118	ywjG	-	-	S	-	-	-	Domain of unknown function (DUF2529)
MDKIOEFL_00479	1.07e-81	spo0F	-	-	T	ko:K02490	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG0784 FOG CheY-like receiver
MDKIOEFL_00480	7.82e-204	fbaA	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Aldolase
MDKIOEFL_00481	5.69e-147	tal	2.2.1.2	-	G	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MDKIOEFL_00482	2.26e-303	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MDKIOEFL_00483	3.51e-225	glpX	3.1.3.11	-	G	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	fructose-1,6-bisphosphatase
MDKIOEFL_00484	5.53e-303	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MDKIOEFL_00485	7e-45	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
MDKIOEFL_00486	9.96e-135	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
MDKIOEFL_00487	0.0	ykwA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
MDKIOEFL_00488	3.24e-204	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
MDKIOEFL_00489	2.93e-108	racA	-	-	K	ko:K11686	-	ko00000,ko03036	Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
MDKIOEFL_00490	4.84e-89	ywkD	-	-	E	ko:K08234	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MDKIOEFL_00491	9.95e-245	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MDKIOEFL_00492	8.46e-205	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MDKIOEFL_00494	9.69e-74	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
MDKIOEFL_00495	9.35e-152	spoIIR	-	-	S	ko:K06387	-	ko00000	stage II sporulation protein R
MDKIOEFL_00496	1.79e-100	ywlB	-	-	E	-	-	-	Belongs to the acetyltransferase family. ArgA subfamily
MDKIOEFL_00497	7.37e-251	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MDKIOEFL_00498	4.56e-117	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
MDKIOEFL_00499	1.58e-100	ywlE	3.1.3.48, 3.9.1.2	-	T	ko:K01104,ko:K20201	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MDKIOEFL_00500	2.35e-106	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase
MDKIOEFL_00501	2.49e-123	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
MDKIOEFL_00502	4.36e-303	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MDKIOEFL_00503	5.5e-148	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MDKIOEFL_00504	1.91e-81	atpI	-	-	S	ko:K02116	-	ko00000,ko00194	ATP synthase
MDKIOEFL_00505	6.06e-167	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
MDKIOEFL_00506	3.01e-36	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MDKIOEFL_00507	2.62e-79	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MDKIOEFL_00508	7.94e-116	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MDKIOEFL_00509	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MDKIOEFL_00510	4.46e-195	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MDKIOEFL_00511	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MDKIOEFL_00512	3.89e-72	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
MDKIOEFL_00513	6.12e-115	ywmA	-	-	-	-	-	-	-
MDKIOEFL_00514	4.54e-45	ywzB	-	-	S	-	-	-	membrane
MDKIOEFL_00515	1.97e-173	ywmB	-	-	S	-	-	-	TATA-box binding
MDKIOEFL_00516	4.96e-306	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MDKIOEFL_00517	1.69e-234	spoIID	-	-	D	ko:K06381	-	ko00000	Stage II sporulation protein D
MDKIOEFL_00518	2.21e-156	ywmC	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
MDKIOEFL_00519	1.02e-155	ywmD	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
MDKIOEFL_00521	2.22e-187	fdhD	-	-	C	ko:K02379	-	ko00000	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MDKIOEFL_00522	1.08e-245	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MDKIOEFL_00523	3.1e-129	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
MDKIOEFL_00525	7.7e-110	ywmF	-	-	S	-	-	-	Peptidase M50
MDKIOEFL_00526	1.11e-21	csbD	-	-	K	-	-	-	CsbD-like
MDKIOEFL_00528	2.16e-27	-	-	-	E	ko:K11963	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
MDKIOEFL_00529	9.59e-67	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease gamma subunit family
MDKIOEFL_00530	1.85e-82	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease beta subunit family
MDKIOEFL_00531	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
MDKIOEFL_00532	4.58e-85	ywnA	-	-	K	-	-	-	Transcriptional regulator
MDKIOEFL_00533	1.19e-144	ywnB	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
MDKIOEFL_00534	1.24e-77	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
MDKIOEFL_00535	2.81e-183	mta	-	-	K	ko:K21743	-	ko00000,ko03000	transcriptional
MDKIOEFL_00536	0.0	ywnE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MDKIOEFL_00537	7.07e-92	ywnF	-	-	S	-	-	-	Family of unknown function (DUF5392)
MDKIOEFL_00538	6.95e-21	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
MDKIOEFL_00539	1.49e-114	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	COG1247 Sortase and related acyltransferases
MDKIOEFL_00540	1.85e-161	spoIIQ	-	-	M	ko:K06386	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
MDKIOEFL_00541	1.21e-134	bcrC	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	COG0671 Membrane-associated phospholipid phosphatase
MDKIOEFL_00542	4.51e-77	nrgB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Belongs to the P(II) protein family
MDKIOEFL_00543	6.5e-288	nrgA	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium transporter
MDKIOEFL_00544	5.04e-101	-	-	-	-	-	-	-	-
MDKIOEFL_00545	1.48e-133	yjgF	-	-	Q	-	-	-	Isochorismatase family
MDKIOEFL_00546	1.27e-305	ywoD	-	-	EGP	-	-	-	Major facilitator superfamily
MDKIOEFL_00547	0.0	-	-	-	FH	ko:K03457,ko:K10975	-	ko00000,ko02000	COG1953 Cytosine uracil thiamine allantoin permeases
MDKIOEFL_00548	1.97e-310	ywoF	-	-	P	-	-	-	Right handed beta helix region
MDKIOEFL_00549	1.37e-269	ywoG	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MDKIOEFL_00550	8.45e-92	-	-	-	K	-	-	-	COG1846 Transcriptional regulators
MDKIOEFL_00551	4.88e-59	spoIIID	-	-	K	ko:K06283	-	ko00000,ko03000	Stage III sporulation protein D
MDKIOEFL_00552	1.75e-231	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein
MDKIOEFL_00553	1.77e-172	flhO	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
MDKIOEFL_00554	1.17e-181	flhP	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
MDKIOEFL_00555	1.5e-254	rapD	-	-	S	ko:K06362	-	ko00000,ko01000	aspartate phosphatase
MDKIOEFL_00556	8.05e-106	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MDKIOEFL_00557	1.61e-77	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MDKIOEFL_00558	0.0	ywpD	-	-	T	-	-	-	Histidine kinase
MDKIOEFL_00559	1.68e-221	M1-574	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
MDKIOEFL_00560	0.0	-	-	-	M	-	-	-	cell wall anchor domain
MDKIOEFL_00561	7.14e-108	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
MDKIOEFL_00562	8.81e-89	ywpF	-	-	S	-	-	-	YwpF-like protein
MDKIOEFL_00563	5.26e-88	ywpG	-	-	-	-	-	-	-
MDKIOEFL_00564	8.53e-76	ssbB	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
MDKIOEFL_00565	4.82e-180	glcR	-	-	K	ko:K22103	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
MDKIOEFL_00566	7.2e-200	ywpJ	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
MDKIOEFL_00567	0.0	ywqA	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
MDKIOEFL_00568	0.0	ywqB	-	-	S	-	-	-	SWIM zinc finger
MDKIOEFL_00569	3.6e-25	-	-	-	-	-	-	-	-
MDKIOEFL_00570	5.33e-163	ywqC	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
MDKIOEFL_00571	1.06e-152	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
MDKIOEFL_00572	2.39e-178	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	COG4464 Capsular polysaccharide biosynthesis protein
MDKIOEFL_00573	1.63e-313	ywqF	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MDKIOEFL_00574	2.08e-196	ywqG	-	-	S	-	-	-	Domain of unknown function (DUF1963)
MDKIOEFL_00576	8.84e-52	ywqI	-	-	S	-	-	-	Family of unknown function (DUF5344)
MDKIOEFL_00577	1.76e-303	ywqJ	-	-	S	-	-	-	Pre-toxin TG
MDKIOEFL_00579	2.92e-148	nfi	3.1.21.7	-	L	ko:K05982	-	ko00000,ko01000,ko03400	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
MDKIOEFL_00580	6.07e-114	ywrA	-	-	P	ko:K07240	-	ko00000,ko02000	COG2059 Chromate transport protein ChrA
MDKIOEFL_00581	4.53e-132	ywrB	-	-	P	ko:K07240	-	ko00000,ko02000	Chromate transporter
MDKIOEFL_00582	2.79e-107	ywrC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
MDKIOEFL_00583	0.0	ywrD	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
MDKIOEFL_00584	5.61e-71	-	-	-	S	-	-	-	Domain of unknown function (DUF4181)
MDKIOEFL_00585	7.22e-142	ywrF	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MDKIOEFL_00586	1.03e-17	-	-	-	-	-	-	-	-
MDKIOEFL_00587	2.08e-265	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
MDKIOEFL_00588	6.97e-172	cotB	-	-	-	ko:K06325	-	ko00000	-
MDKIOEFL_00589	1.06e-162	ywrJ	-	-	-	-	-	-	-
MDKIOEFL_00590	1.32e-278	ywrK	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MDKIOEFL_00591	3.36e-218	alsR	-	-	K	-	-	-	LysR substrate binding domain
MDKIOEFL_00592	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
MDKIOEFL_00593	1.51e-186	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
MDKIOEFL_00594	3.57e-125	ywrO	-	-	S	-	-	-	NADPH-quinone reductase (modulator of drug activity B)
MDKIOEFL_00595	3.75e-63	ywsA	-	-	S	-	-	-	Protein of unknown function (DUF3892)
MDKIOEFL_00596	3.97e-119	batE	-	-	T	-	-	-	Sh3 type 3 domain protein
MDKIOEFL_00597	3.68e-203	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	COG1879 ABC-type sugar transport system, periplasmic component
MDKIOEFL_00598	3.35e-203	rbsC	-	-	G	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MDKIOEFL_00599	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
MDKIOEFL_00600	5.39e-83	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MDKIOEFL_00601	2.94e-203	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MDKIOEFL_00602	2.68e-227	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
MDKIOEFL_00603	1.46e-283	capB	-	-	M	ko:K01932	-	ko00000,ko01000	COG0769 UDP-N-acetylmuramyl tripeptide synthase
MDKIOEFL_00604	8.44e-91	capC	-	-	S	ko:K22116	-	ko00000	biosynthesis protein
MDKIOEFL_00605	1.1e-276	capA	-	-	M	ko:K07282	-	ko00000	enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
MDKIOEFL_00606	2.29e-29	ywtC	-	-	-	-	-	-	-
MDKIOEFL_00607	2.27e-303	pgdS	-	-	M	-	-	-	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MDKIOEFL_00608	4.02e-202	ywtE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
MDKIOEFL_00609	1.29e-180	ywtF_2	-	-	K	-	-	-	Transcriptional regulator
MDKIOEFL_00610	9.1e-315	ywtG	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MDKIOEFL_00611	1.95e-251	gerBC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination protein
MDKIOEFL_00612	2.06e-239	gerBB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
MDKIOEFL_00613	5.41e-311	gerBA	-	-	EG	ko:K06291,ko:K06310	-	ko00000	Spore germination protein
MDKIOEFL_00614	2.62e-238	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
MDKIOEFL_00615	0.0	lytD	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MDKIOEFL_00616	4.99e-236	tarL	2.7.8.14, 2.7.8.47	-	M	ko:K18704	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MDKIOEFL_00617	6.69e-110	tarK	2.7.8.14, 2.7.8.46, 2.7.8.47	-	M	ko:K18704,ko:K21592	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MDKIOEFL_00618	5.68e-186	tarJ	1.1.1.137, 1.1.1.405	-	E	ko:K05352,ko:K21680	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
MDKIOEFL_00619	2.07e-134	tarI	2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21030	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
MDKIOEFL_00620	5.44e-117	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MDKIOEFL_00621	6.82e-111	tagA	2.4.1.187	GT26	M	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MDKIOEFL_00622	1.32e-73	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Cytidylyltransferase
MDKIOEFL_00623	6.53e-180	tagF	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MDKIOEFL_00624	2.07e-106	-	-	-	M	-	-	-	Glycosyltransferase like family 2
MDKIOEFL_00625	1.07e-248	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MDKIOEFL_00626	1.9e-68	-	-	-	-	-	-	-	-
MDKIOEFL_00627	1.43e-102	-	-	-	-	-	-	-	-
MDKIOEFL_00628	1.37e-167	tagG	-	-	GM	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
MDKIOEFL_00629	0.0	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MDKIOEFL_00630	2.74e-208	gtaB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
MDKIOEFL_00632	3.05e-119	-	-	-	M	-	-	-	Glycosyl transferases group 1
MDKIOEFL_00633	1.48e-103	-	-	-	M	-	-	-	Glycosyltransferase like family 2
MDKIOEFL_00634	3.14e-276	mnaA	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MDKIOEFL_00635	1.16e-211	lytR	-	-	K	-	-	-	May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
MDKIOEFL_00636	9.07e-16	-	-	-	-	-	-	-	-
MDKIOEFL_00637	0.0	lytB	-	-	D	-	-	-	Stage II sporulation protein
MDKIOEFL_00638	5.81e-261	lytC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
MDKIOEFL_00639	1.78e-108	-	-	-	M	-	-	-	Glycosyltransferase like family 2
MDKIOEFL_00640	1.49e-143	tuaA	-	-	M	-	-	-	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MDKIOEFL_00641	3.44e-316	tuaB	-	-	S	ko:K03328,ko:K16694,ko:K16695	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MDKIOEFL_00642	9.81e-280	tuaC	-	GT4	GM	ko:K16697	-	ko00000,ko01000,ko01003	Teichuronic acid
MDKIOEFL_00643	0.0	tuaD	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MDKIOEFL_00644	0.0	tuaE	-	-	M	ko:K16705	-	ko00000	Teichuronic acid biosynthesis protein
MDKIOEFL_00645	5.79e-147	tuaF	-	-	M	ko:K16706	-	ko00000	protein involved in exopolysaccharide biosynthesis
MDKIOEFL_00646	2.41e-186	tuaG	-	GT2	M	ko:K16698	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
MDKIOEFL_00647	2.39e-296	tuaH	-	-	M	ko:K16699	-	ko00000,ko01000,ko01003	Teichuronic acid biosynthesis glycosyltransferase tuaH
MDKIOEFL_00648	2.1e-231	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
MDKIOEFL_00649	9.37e-224	yvhJ	-	-	K	-	-	-	Transcriptional regulator
MDKIOEFL_00650	2.41e-155	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	Domain of unknown function (DUF1949)
MDKIOEFL_00651	2.94e-247	degS	2.7.13.3	-	T	ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
MDKIOEFL_00652	7.16e-163	degU	-	-	KT	ko:K02479,ko:K07692	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MDKIOEFL_00653	2.51e-198	degV	-	-	S	-	-	-	protein conserved in bacteria
MDKIOEFL_00654	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MDKIOEFL_00655	1.26e-61	comFB	-	-	S	ko:K02241	-	ko00000,ko00002,ko02044	Late competence development protein ComFB
MDKIOEFL_00656	2.26e-162	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Phosphoribosyl transferase domain
MDKIOEFL_00657	1.83e-96	yvyF	-	-	S	-	-	-	flagellar protein
MDKIOEFL_00658	8.4e-51	flgM	-	-	KNU	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	ko00000,ko00001,ko02035	Negative regulator of flagellin synthesis
MDKIOEFL_00659	5.8e-101	yvyG	-	-	NOU	-	-	-	FlgN protein
MDKIOEFL_00660	0.0	flgK	-	-	N	ko:K02396	ko02040,map02040	ko00000,ko00001,ko02035	flagellar hook-associated protein
MDKIOEFL_00661	3.8e-197	flgL	-	-	N	ko:K02397	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the bacterial flagellin family
MDKIOEFL_00662	6.92e-92	yviE	-	-	-	-	-	-	-
MDKIOEFL_00663	1.23e-96	fliW	-	-	S	ko:K13626	-	ko00000,ko02035	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
MDKIOEFL_00664	3.02e-40	csrA	-	-	T	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	ko00000,ko00001,ko03019	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
MDKIOEFL_00665	8.01e-202	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MDKIOEFL_00666	1.1e-76	flaG	-	-	N	ko:K06603	-	ko00000,ko02035	flagellar protein FlaG
MDKIOEFL_00667	0.0	fliD	-	-	N	ko:K02407	ko02040,map02040	ko00000,ko00001,ko02035	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MDKIOEFL_00668	5.15e-91	fliS	-	-	N	ko:K02422	ko02040,map02040	ko00000,ko00001,ko02035	flagellar protein FliS
MDKIOEFL_00669	8.69e-09	fliT	-	-	S	ko:K02423	ko02040,map02040	ko00000,ko00001,ko02035	bacterial-type flagellum organization
MDKIOEFL_00670	7.52e-87	-	-	-	-	-	-	-	-
MDKIOEFL_00671	1.73e-132	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MDKIOEFL_00672	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MDKIOEFL_00673	2e-232	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MDKIOEFL_00674	1.53e-183	yvjA	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MDKIOEFL_00675	4.42e-73	cccB	-	-	C	ko:K12263,ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
MDKIOEFL_00676	1.5e-159	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
MDKIOEFL_00677	5.45e-199	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
MDKIOEFL_00678	0.0	ctpB	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
MDKIOEFL_00679	1.38e-73	swrA	-	-	S	-	-	-	Swarming motility protein
MDKIOEFL_00680	3.17e-280	minJ	-	-	O	-	-	-	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MDKIOEFL_00681	1.23e-294	yvkA	-	-	P	-	-	-	-transporter
MDKIOEFL_00682	1.43e-131	yvkB	-	-	K	-	-	-	Transcriptional regulator
MDKIOEFL_00683	0.0	yvkC	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Phosphotransferase
MDKIOEFL_00684	2.54e-42	csbA	-	-	S	-	-	-	protein conserved in bacteria
MDKIOEFL_00685	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MDKIOEFL_00686	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MDKIOEFL_00687	3.5e-102	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MDKIOEFL_00688	6.45e-45	yvkN	-	-	-	-	-	-	-
MDKIOEFL_00689	3.3e-64	yvlA	-	-	-	-	-	-	-
MDKIOEFL_00690	9.59e-220	yvlB	-	-	S	-	-	-	Putative adhesin
MDKIOEFL_00691	1.5e-36	yvlC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
MDKIOEFL_00692	3.8e-66	yvlD	-	-	S	ko:K08972	-	ko00000	Membrane
MDKIOEFL_00693	2.46e-271	yvmA	-	-	EGP	-	-	-	Major Facilitator Superfamily
MDKIOEFL_00694	6.2e-114	yvmB	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MDKIOEFL_00695	8.35e-176	yvmC	2.3.2.22	-	S	ko:K17485	-	ko00000,ko01000	Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
MDKIOEFL_00696	2.45e-288	cypX	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
MDKIOEFL_00697	4.06e-94	yvnA	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MDKIOEFL_00698	0.0	yvnB	-	-	Q	-	-	-	Calcineurin-like phosphoesterase
MDKIOEFL_00699	3.02e-171	yvoA	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
MDKIOEFL_00700	2.21e-168	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MDKIOEFL_00701	9.81e-279	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MDKIOEFL_00702	3.62e-217	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MDKIOEFL_00703	2.61e-194	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MDKIOEFL_00704	8.38e-208	yvoD	-	-	P	-	-	-	COG0370 Fe2 transport system protein B
MDKIOEFL_00705	3.05e-153	ppaX	3.6.1.1	-	S	ko:K06019	ko00190,map00190	ko00000,ko00001,ko01000	Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
MDKIOEFL_00706	3.58e-119	yvoF	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
MDKIOEFL_00707	1.05e-151	-	4.2.2.10, 4.2.2.2	-	G	ko:K19551	ko00040,map00040	ko00000,ko00001,ko01000	Pectate lyase
MDKIOEFL_00708	6.12e-179	yvpB	-	-	NU	-	-	-	protein conserved in bacteria
MDKIOEFL_00709	5.69e-280	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MDKIOEFL_00710	1.06e-147	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MDKIOEFL_00711	5.2e-292	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MDKIOEFL_00712	4.96e-139	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
MDKIOEFL_00713	1.1e-144	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MDKIOEFL_00714	1.04e-163	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MDKIOEFL_00715	2.29e-175	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MDKIOEFL_00716	1.7e-142	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the PRA-CH family
MDKIOEFL_00717	1.29e-111	-	-	-	-	-	-	-	-
MDKIOEFL_00718	0.0	-	-	-	-	-	-	-	-
MDKIOEFL_00720	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
MDKIOEFL_00721	0.0	yvcD	-	-	S	-	-	-	COG0457 FOG TPR repeat
MDKIOEFL_00722	4.97e-188	spl	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	protein conserved in bacteria
MDKIOEFL_00723	1.18e-225	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MDKIOEFL_00724	2.39e-117	yvcI	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
MDKIOEFL_00725	8.53e-213	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
MDKIOEFL_00726	6.72e-227	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
MDKIOEFL_00727	1.04e-219	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
MDKIOEFL_00728	3.92e-50	crh	-	-	G	ko:K11184	-	ko00000	Phosphocarrier protein Chr
MDKIOEFL_00729	5.2e-179	yvcN	2.3.1.118	-	Q	ko:K00675	-	ko00000,ko01000	Belongs to the arylamine N-acetyltransferase family
MDKIOEFL_00730	5.4e-43	-	-	-	-	-	-	-	-
MDKIOEFL_00731	3.84e-171	yvcP	-	-	T	ko:K02483,ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MDKIOEFL_00732	2.28e-250	yvcQ	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
MDKIOEFL_00733	4.46e-181	yxdL_2	-	-	V	ko:K02003,ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MDKIOEFL_00734	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
MDKIOEFL_00735	2.7e-233	yvcT	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MDKIOEFL_00736	8.79e-136	yvdA	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
MDKIOEFL_00737	0.0	yvdB	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
MDKIOEFL_00738	7.84e-71	yvdC	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
MDKIOEFL_00739	5.37e-137	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
MDKIOEFL_00740	6.28e-221	yvdE	-	-	K	-	-	-	Transcriptional regulator
MDKIOEFL_00741	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, N-terminal ig-like domain
MDKIOEFL_00742	5.95e-302	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
MDKIOEFL_00743	2.37e-308	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
MDKIOEFL_00744	1.96e-189	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
MDKIOEFL_00745	1.34e-200	malA	-	-	S	-	-	-	Protein of unknown function (DUF1189)
MDKIOEFL_00746	0.0	yvdK	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycoside hydrolase, family 65
MDKIOEFL_00747	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
MDKIOEFL_00748	5.57e-149	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
MDKIOEFL_00749	8.17e-135	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MDKIOEFL_00751	1.12e-121	yvdQ	-	-	S	-	-	-	Protein of unknown function (DUF3231)
MDKIOEFL_00752	5.98e-66	yvdR	-	-	P	ko:K11741	-	ko00000,ko02000	Small Multidrug Resistance protein
MDKIOEFL_00753	2.57e-67	yvdS	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
MDKIOEFL_00754	4.76e-137	yvdT_1	-	-	K	-	-	-	Transcriptional regulator
MDKIOEFL_00755	0.0	ybeC	-	-	E	-	-	-	amino acid
MDKIOEFL_00756	0.0	sacC3	3.2.1.65	GH32	G	ko:K01212	ko00500,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
MDKIOEFL_00757	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	levansucrase activity
MDKIOEFL_00758	7.19e-86	-	-	-	-	-	-	-	-
MDKIOEFL_00759	0.0	pbpE	-	-	V	-	-	-	Beta-lactamase
MDKIOEFL_00760	2.06e-161	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
MDKIOEFL_00761	1.75e-93	-	-	-	S	-	-	-	Protein of unknown function (DUF3237)
MDKIOEFL_00762	5.4e-120	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
MDKIOEFL_00764	0.0	pnbA	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
MDKIOEFL_00765	3.57e-98	-	-	-	K	ko:K19417	-	ko00000,ko03000	transcriptional
MDKIOEFL_00766	1.61e-157	epsA	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
MDKIOEFL_00767	7.94e-150	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
MDKIOEFL_00768	0.0	capD	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
MDKIOEFL_00769	7.45e-280	epsD	-	GT4	M	ko:K19422	-	ko00000,ko01000	Glycosyl transferase 4-like
MDKIOEFL_00770	1.25e-201	epsE	-	GT2	M	ko:K19423	-	ko00000,ko01000,ko01003	COG0463 Glycosyltransferases involved in cell wall biogenesis
MDKIOEFL_00771	1.28e-277	epsF	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
MDKIOEFL_00772	8.82e-265	epsG	-	-	S	ko:K19419	-	ko00000,ko02000	EpsG family
MDKIOEFL_00773	4.97e-248	epsH	-	GT2	S	ko:K19425	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
MDKIOEFL_00774	1.57e-258	epsI	-	-	GM	ko:K19426	-	ko00000,ko01000	pyruvyl transferase
MDKIOEFL_00775	4.76e-246	epsJ	-	GT2	S	ko:K19427	-	ko00000,ko01000	COG0463 Glycosyltransferases involved in cell wall biogenesis
MDKIOEFL_00776	0.0	epsK	-	-	S	ko:K19418	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MDKIOEFL_00777	9.14e-139	epsL	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MDKIOEFL_00778	8.22e-77	epsM	-	-	GM	ko:K19429	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
MDKIOEFL_00779	8.7e-278	epsN	-	-	E	ko:K19430	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
MDKIOEFL_00780	1.46e-238	epsO	-	-	GM	ko:K19431	-	ko00000,ko01000	Exopolysaccharide biosynthesis protein
MDKIOEFL_00781	5.69e-44	yvfG	-	-	S	-	-	-	YvfG protein
MDKIOEFL_00782	1.36e-303	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
MDKIOEFL_00783	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
MDKIOEFL_00784	6.85e-146	yvfI	-	-	K	ko:K05799	-	ko00000,ko03000	COG2186 Transcriptional regulators
MDKIOEFL_00785	6.96e-237	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
MDKIOEFL_00786	4.62e-292	cycB	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
MDKIOEFL_00787	2.15e-300	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
MDKIOEFL_00788	3.82e-194	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
MDKIOEFL_00789	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	beta-galactosidase
MDKIOEFL_00790	0.0	ganB	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
MDKIOEFL_00791	2.06e-263	-	3.1.3.3	-	T	ko:K07315	-	ko00000,ko01000,ko03021	response regulator
MDKIOEFL_00792	1.46e-200	rsbQ	-	-	S	ko:K19707	-	ko00000,ko03021	Alpha/beta hydrolase family
MDKIOEFL_00794	7.76e-205	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
MDKIOEFL_00795	2.04e-170	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
MDKIOEFL_00796	1.41e-247	yvfT	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MDKIOEFL_00797	2.07e-134	desR	-	-	T	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MDKIOEFL_00798	9.08e-175	lutA	-	-	C	ko:K18928	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MDKIOEFL_00799	0.0	lutB	-	-	C	ko:K18929	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
MDKIOEFL_00800	1.39e-170	lutC	-	-	S	ko:K00782	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MDKIOEFL_00801	6.04e-249	-	-	-	S	-	-	-	Glycosyl hydrolase
MDKIOEFL_00802	7.07e-307	yvbW	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
MDKIOEFL_00803	1.6e-197	yvbV	-	-	EG	-	-	-	EamA-like transporter family
MDKIOEFL_00804	4.9e-206	yvbU	-	-	K	-	-	-	Transcriptional regulator
MDKIOEFL_00805	1.04e-245	yvbT	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MDKIOEFL_00806	1.51e-258	araR	-	-	K	ko:K02103	-	ko00000,ko03000	transcriptional
MDKIOEFL_00807	0.0	araE	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MDKIOEFL_00808	2.42e-237	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MDKIOEFL_00809	5.72e-238	gapA	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MDKIOEFL_00810	1.97e-277	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
MDKIOEFL_00811	2.12e-176	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MDKIOEFL_00812	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and
MDKIOEFL_00813	1.38e-309	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MDKIOEFL_00814	9.77e-106	yvbK	-	-	K	-	-	-	acetyltransferase
MDKIOEFL_00815	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
MDKIOEFL_00816	2.28e-156	yvbI	-	-	M	-	-	-	Membrane
MDKIOEFL_00817	2.96e-145	yvbH	-	-	S	-	-	-	YvbH-like oligomerisation region
MDKIOEFL_00818	2.77e-135	yvbG	-	-	U	ko:K05595	-	ko00000,ko02000	UPF0056 membrane protein
MDKIOEFL_00819	8.29e-129	yvbF	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
MDKIOEFL_00820	5.58e-270	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MDKIOEFL_00821	5.63e-145	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
MDKIOEFL_00822	3.52e-221	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MDKIOEFL_00823	2.28e-135	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
MDKIOEFL_00824	9.42e-122	yvbF	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
MDKIOEFL_00825	3.64e-271	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MDKIOEFL_00826	3.65e-141	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
MDKIOEFL_00827	7.93e-219	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MDKIOEFL_00828	2.48e-134	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
MDKIOEFL_00829	6.45e-231	-	-	-	S	-	-	-	Lantibiotic dehydratase, C terminus
MDKIOEFL_00830	8.57e-193	-	-	-	V	ko:K06147,ko:K06148,ko:K20485	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	ABC transporter
MDKIOEFL_00831	3.32e-97	spaC1	-	-	V	ko:K20484	ko02020,ko02024,map02020,map02024	ko00000,ko00001	Lanthionine synthetase C-like protein
MDKIOEFL_00834	7.1e-131	spaF	-	-	V	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MDKIOEFL_00835	1.67e-110	spaE	-	-	S	ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
MDKIOEFL_00836	2.99e-103	spaG	-	-	S	ko:K20492	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
MDKIOEFL_00837	1.41e-135	spaR	-	-	K	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
MDKIOEFL_00838	1.03e-194	spaK	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
MDKIOEFL_00839	0.0	yvaQ	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MDKIOEFL_00840	3.85e-72	yvaP	-	-	K	-	-	-	transcriptional
MDKIOEFL_00841	9.82e-92	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
MDKIOEFL_00842	2.36e-91	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	transcriptional
MDKIOEFL_00843	4.9e-48	yvzC	-	-	K	-	-	-	transcriptional
MDKIOEFL_00844	2.33e-195	yvaM	1.11.1.10	-	S	ko:K00433	-	ko00000,ko01000	Serine aminopeptidase, S33
MDKIOEFL_00845	1.87e-35	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit SecG
MDKIOEFL_00846	3.43e-183	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Carboxylesterase
MDKIOEFL_00847	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MDKIOEFL_00848	2.4e-107	smpB	-	-	O	ko:K03664	-	ko00000	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MDKIOEFL_00851	4.89e-22	-	-	-	-	-	-	-	-
MDKIOEFL_00852	3.96e-182	yvaG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
MDKIOEFL_00853	5.77e-127	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MDKIOEFL_00854	4.12e-70	yvaE	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
MDKIOEFL_00855	3.35e-96	yvaD	-	-	S	-	-	-	Family of unknown function (DUF5360)
MDKIOEFL_00856	0.0	-	-	-	S	-	-	-	Fusaric acid resistance protein-like
MDKIOEFL_00857	2.08e-153	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MDKIOEFL_00858	1.99e-247	yvaA	1.1.1.371	-	S	ko:K16044	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
MDKIOEFL_00859	6.89e-65	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	transcriptional
MDKIOEFL_00860	3.66e-41	copZ	-	-	P	ko:K07213	ko04978,map04978	ko00000,ko00001	Copper resistance protein CopZ
MDKIOEFL_00861	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
MDKIOEFL_00862	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
MDKIOEFL_00863	3.45e-137	bdbD	-	-	O	-	-	-	Thioredoxin
MDKIOEFL_00864	1.99e-95	bdbC	-	-	O	ko:K03611	-	ko00000,ko03110	Required for disulfide bond formation in some proteins
MDKIOEFL_00865	2.34e-139	yvgT	-	-	S	-	-	-	membrane
MDKIOEFL_00867	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
MDKIOEFL_00868	0.0	cysJ	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MDKIOEFL_00869	0.0	cysI	1.8.1.2, 1.8.7.1	-	P	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
MDKIOEFL_00870	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	COG0025 NhaP-type Na H and K H antiporters
MDKIOEFL_00871	9.32e-112	yvgO	-	-	-	-	-	-	-
MDKIOEFL_00872	1.77e-200	yvgN	-	-	S	-	-	-	reductase
MDKIOEFL_00873	1.74e-153	modB	-	-	P	ko:K02018	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4149 ABC-type molybdate transport system, permease component
MDKIOEFL_00874	2.11e-175	modA	-	-	P	ko:K02020	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0725 ABC-type molybdate transport system, periplasmic component
MDKIOEFL_00875	1.21e-212	yvgK	-	-	P	ko:K07219	-	ko00000	COG1910 Periplasmic molybdate-binding protein domain
MDKIOEFL_00876	0.0	yvgJ	-	-	M	ko:K01138	-	ko00000,ko01000	Belongs to the LTA synthase family
MDKIOEFL_00877	2.38e-109	yvsG	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
MDKIOEFL_00878	9.37e-23	-	-	-	S	ko:K06427	-	ko00000	Small spore protein J (Spore_SspJ)
MDKIOEFL_00879	0.0	yvsH	-	-	E	ko:K03294,ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
MDKIOEFL_00881	6.32e-225	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MDKIOEFL_00882	1.21e-236	fhuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MDKIOEFL_00883	4.78e-226	fhuG	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MDKIOEFL_00884	2.92e-191	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MDKIOEFL_00885	8.47e-230	-	-	-	M	ko:K02005	-	ko00000	Efflux transporter rnd family, mfp subunit
MDKIOEFL_00886	3.82e-158	yvrO	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MDKIOEFL_00887	9.64e-272	yvrN	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
MDKIOEFL_00888	1.64e-84	yvrL	-	-	S	-	-	-	Regulatory protein YrvL
MDKIOEFL_00889	1.86e-291	oxdC	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
MDKIOEFL_00890	3.46e-26	-	-	-	S	-	-	-	YvrJ protein family
MDKIOEFL_00891	7.02e-128	yvrI	-	-	K	ko:K03093	-	ko00000,ko03021	RNA polymerase
MDKIOEFL_00892	6.16e-33	-	-	-	-	-	-	-	-
MDKIOEFL_00893	1.1e-170	yvrH	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MDKIOEFL_00894	0.0	yvrG	-	-	T	-	-	-	Histidine kinase
MDKIOEFL_00895	1.32e-219	yvrE	-	-	G	ko:K14274	ko00040,map00040	ko00000,ko00001,ko01000	SMP-30/Gluconolaconase/LRE-like region
MDKIOEFL_00896	1.23e-180	yvrD	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
MDKIOEFL_00897	2.98e-218	btuF	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
MDKIOEFL_00898	1.9e-236	btuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MDKIOEFL_00899	5.2e-309	yvrA	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
MDKIOEFL_00900	1.93e-131	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Adenosyltransferase
MDKIOEFL_00901	6.23e-286	yvqJ	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MDKIOEFL_00902	1.51e-82	liaI	-	-	S	ko:K11619	ko02020,map02020	ko00000,ko00001,ko00002	membrane
MDKIOEFL_00903	9.94e-143	liaH	-	-	KT	ko:K03969,ko:K11620	ko02020,map02020	ko00000,ko00001,ko00002	COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
MDKIOEFL_00904	2.19e-176	liaG	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
MDKIOEFL_00905	7.65e-164	-	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
MDKIOEFL_00906	4.06e-246	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MDKIOEFL_00907	4.46e-139	vraR	-	-	KT	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MDKIOEFL_00908	3.05e-243	gerAC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination B3/ GerAC like, C-terminal
MDKIOEFL_00909	3.94e-251	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
MDKIOEFL_00910	0.0	gerAA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
MDKIOEFL_00911	2.6e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF3970)
MDKIOEFL_00912	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MDKIOEFL_00913	3.06e-204	yuxN	-	-	K	-	-	-	Transcriptional regulator
MDKIOEFL_00914	2.77e-316	cssS	2.7.13.3	-	T	ko:K07650	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MDKIOEFL_00915	2.23e-164	cssR	-	-	T	ko:K07770	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MDKIOEFL_00916	7.9e-305	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MDKIOEFL_00917	2.15e-104	fri	-	-	P	ko:K04047	-	ko00000,ko03036	Ferritin-like domain
MDKIOEFL_00918	4.49e-196	yusZ	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
MDKIOEFL_00919	0.0	pepF2	-	-	E	-	-	-	COG1164 Oligoendopeptidase F
MDKIOEFL_00920	3.48e-88	-	-	-	S	-	-	-	YusW-like protein
MDKIOEFL_00921	1.24e-195	yusV	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MDKIOEFL_00922	3.99e-53	yusU	-	-	S	-	-	-	Protein of unknown function (DUF2573)
MDKIOEFL_00923	8.42e-204	gltR	-	-	K	ko:K21959	-	ko00000,ko03000	LysR substrate binding domain
MDKIOEFL_00924	1.22e-138	yusR	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
MDKIOEFL_00925	1.7e-84	yusQ	-	-	S	-	-	-	Tautomerase enzyme
MDKIOEFL_00926	0.0	yusP	-	-	P	-	-	-	Major facilitator superfamily
MDKIOEFL_00927	6.35e-98	yusO	-	-	K	-	-	-	Iron dependent repressor, N-terminal DNA binding domain
MDKIOEFL_00928	8.66e-70	yusN	-	-	M	-	-	-	Coat F domain
MDKIOEFL_00929	2.23e-54	-	-	-	-	-	-	-	-
MDKIOEFL_00930	1.58e-207	fadM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
MDKIOEFL_00931	1.11e-13	-	-	-	S	-	-	-	YuzL-like protein
MDKIOEFL_00932	0.0	fadN	1.1.1.35	-	I	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	ko00000,ko00001,ko00002,ko01000	3-hydroxyacyl-CoA dehydrogenase
MDKIOEFL_00933	1.34e-278	fadA	2.3.1.16	-	I	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the thiolase family
MDKIOEFL_00934	0.0	fadE	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
MDKIOEFL_00935	1.01e-83	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
MDKIOEFL_00936	5.91e-85	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
MDKIOEFL_00937	7.34e-54	yusG	-	-	S	-	-	-	Protein of unknown function (DUF2553)
MDKIOEFL_00938	2.18e-96	yusF	-	-	L	ko:K07476	-	ko00000	COG1658 Small primase-like proteins (Toprim domain)
MDKIOEFL_00939	5.73e-73	yusE	-	-	CO	-	-	-	Thioredoxin
MDKIOEFL_00940	1.53e-74	yusD	-	-	S	-	-	-	SCP-2 sterol transfer family
MDKIOEFL_00941	3.05e-236	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MDKIOEFL_00942	6.5e-126	metI	-	-	P	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2011 ABC-type metal ion transport system, permease component
MDKIOEFL_00943	5.86e-189	metQ	-	-	P	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
MDKIOEFL_00944	1.56e-80	yurZ	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MDKIOEFL_00945	4.46e-182	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
MDKIOEFL_00946	3.53e-311	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	assembly protein SufD
MDKIOEFL_00947	1.14e-298	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MDKIOEFL_00948	6.26e-101	nifU	-	-	C	ko:K04488	-	ko00000	COG0822 NifU homolog involved in Fe-S cluster formation
MDKIOEFL_00949	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	FeS cluster assembly
MDKIOEFL_00950	5.06e-86	yurT	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MDKIOEFL_00951	4.95e-51	-	-	-	-	-	-	-	-
MDKIOEFL_00953	1.59e-265	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	COG0665 Glycine D-amino acid oxidases (deaminating)
MDKIOEFL_00954	1.2e-87	yurQ	-	-	L	-	-	-	COG0322 Nuclease subunit of the excinuclease complex
MDKIOEFL_00955	5.27e-235	frlB	-	-	M	ko:K10708	-	ko00000,ko01000	Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
MDKIOEFL_00956	1.66e-306	yurO	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
MDKIOEFL_00957	3.54e-199	yurN	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MDKIOEFL_00958	1.94e-216	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
MDKIOEFL_00959	9.57e-209	-	2.7.1.218	-	G	ko:K10710	-	ko00000,ko01000	pfkB family carbohydrate kinase
MDKIOEFL_00960	8.71e-175	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
MDKIOEFL_00961	9.87e-262	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MDKIOEFL_00962	6.53e-218	bsn	-	-	L	-	-	-	Ribonuclease
MDKIOEFL_00963	3.39e-294	pucF	3.5.3.9	-	E	ko:K02083	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000,ko01002	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
MDKIOEFL_00964	3.87e-302	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
MDKIOEFL_00965	3.05e-235	pucA	1.17.1.4	-	O	ko:K00087,ko:K07402	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MDKIOEFL_00966	7.22e-142	pucB	1.17.1.4, 2.7.7.76	-	S	ko:K00087,ko:K07141	ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120	ko00000,ko00001,ko00002,ko01000	MobA-like NTP transferase domain
MDKIOEFL_00967	4.27e-188	pucC	1.17.1.4, 1.2.5.3	-	C	ko:K00087,ko:K03519	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
MDKIOEFL_00968	0.0	pucD	1.17.1.4	-	C	ko:K00087	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
MDKIOEFL_00969	4.02e-121	-	1.17.1.4, 1.2.5.3	-	C	ko:K00087,ko:K03518	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
MDKIOEFL_00970	0.000108	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
MDKIOEFL_00971	1.72e-71	pucM	3.5.2.17	-	S	ko:K07127	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
MDKIOEFL_00972	0.0	-	1.7.3.3, 4.1.1.97	-	Q	ko:K16838	ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
MDKIOEFL_00973	1.11e-283	pbuX	-	-	F	ko:K16169,ko:K16170	-	ko00000,ko02000	xanthine
MDKIOEFL_00974	1.81e-292	pbuX	-	-	F	ko:K03458,ko:K16169,ko:K16170	-	ko00000,ko02000	Permease family
MDKIOEFL_00975	0.0	pucR	-	-	QT	ko:K09684	-	ko00000,ko03000	COG2508 Regulator of polyketide synthase expression
MDKIOEFL_00976	0.0	allB	3.5.2.5	-	F	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
MDKIOEFL_00977	3.06e-79	yunG	-	-	-	-	-	-	-
MDKIOEFL_00978	4.26e-220	yunF	-	-	S	-	-	-	Protein of unknown function DUF72
MDKIOEFL_00979	6.51e-181	yunE	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MDKIOEFL_00980	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MDKIOEFL_00981	1.39e-64	yunC	-	-	S	-	-	-	Domain of unknown function (DUF1805)
MDKIOEFL_00982	3.49e-169	yunB	-	-	S	-	-	-	Sporulation protein YunB (Spo_YunB)
MDKIOEFL_00983	2.66e-252	lytH	-	-	M	ko:K21472	-	ko00000,ko01000,ko01002,ko01011	Peptidase, M23
MDKIOEFL_00984	1.37e-215	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MDKIOEFL_00985	1.34e-144	yutC	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MDKIOEFL_00986	3.2e-63	yutD	-	-	S	-	-	-	protein conserved in bacteria
MDKIOEFL_00987	2.38e-99	yutE	-	-	S	-	-	-	Protein of unknown function DUF86
MDKIOEFL_00988	2.13e-182	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MDKIOEFL_00989	2.26e-101	yutG	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
MDKIOEFL_00990	1.74e-252	yutH	-	-	S	-	-	-	Spore coat protein
MDKIOEFL_00991	1.67e-307	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
MDKIOEFL_00992	5.64e-252	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MDKIOEFL_00993	2.57e-221	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MDKIOEFL_00994	0.0	yuxL	3.4.19.1	-	EU	ko:K01303	-	ko00000,ko01000,ko01002	peptidase
MDKIOEFL_00995	1.26e-47	yutI	-	-	O	-	-	-	COG0694 Thioredoxin-like proteins and domains
MDKIOEFL_00996	2.7e-74	yuzD	-	-	S	-	-	-	protein conserved in bacteria
MDKIOEFL_00997	1.12e-253	yutJ	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
MDKIOEFL_00998	1.74e-52	yuzB	-	-	S	-	-	-	Belongs to the UPF0349 family
MDKIOEFL_00999	6.25e-270	yutK	-	-	F	ko:K03317	-	ko00000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MDKIOEFL_01000	2.25e-207	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MDKIOEFL_01001	6.81e-83	erpA	-	-	S	ko:K13628	-	ko00000,ko03016	Belongs to the HesB IscA family
MDKIOEFL_01002	6.88e-116	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MDKIOEFL_01003	8.15e-149	paiB	-	-	K	ko:K07734	-	ko00000,ko03000	Putative FMN-binding domain
MDKIOEFL_01004	5.26e-234	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MDKIOEFL_01006	1.16e-240	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	reductase
MDKIOEFL_01007	4.16e-301	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
MDKIOEFL_01008	9.78e-47	yuiB	-	-	S	-	-	-	Putative membrane protein
MDKIOEFL_01009	1.5e-149	yuiC	-	-	S	-	-	-	protein conserved in bacteria
MDKIOEFL_01010	8.63e-102	yuiD	-	-	S	ko:K09775	-	ko00000	protein conserved in bacteria
MDKIOEFL_01011	0.0	pepA	3.4.11.1	-	E	ko:K01255	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MDKIOEFL_01012	3.65e-279	yuiF	-	-	S	ko:K07084	-	ko00000,ko02000	antiporter
MDKIOEFL_01013	8.33e-125	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Biotin biosynthesis protein
MDKIOEFL_01014	2.36e-157	yuiH	-	-	S	-	-	-	Oxidoreductase molybdopterin binding domain
MDKIOEFL_01015	1.26e-211	eSD	-	-	S	ko:K07017	-	ko00000	Putative esterase
MDKIOEFL_01016	4.1e-178	dhbA	1.3.1.28	-	IQ	ko:K00216	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
MDKIOEFL_01017	2.99e-290	dhbC	5.4.4.2	-	HQ	ko:K02361	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
MDKIOEFL_01018	0.0	entE	2.7.7.58, 6.3.2.14	-	Q	ko:K02363,ko:K04783	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	2,3-dihydroxybenzoate-AMP ligase
MDKIOEFL_01019	1.1e-228	dhbB	3.3.2.1, 6.3.2.14	-	Q	ko:K01252	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	Isochorismatase family
MDKIOEFL_01020	0.0	dhbF	-	-	Q	ko:K04780	ko01053,map01053	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDKIOEFL_01021	2.02e-47	mbtH	-	-	S	ko:K05375	ko00261,ko01130,map00261,map01130	ko00000,ko00001,ko00002	MbtH-like protein
MDKIOEFL_01022	1.2e-168	yukJ	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2278)
MDKIOEFL_01023	1.64e-261	ald	1.4.1.1	-	E	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
MDKIOEFL_01024	4.7e-289	yukF	-	-	QT	-	-	-	Transcriptional regulator
MDKIOEFL_01025	3.93e-60	yukE	-	-	S	-	-	-	Belongs to the WXG100 family
MDKIOEFL_01026	1.93e-54	yukD	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukD
MDKIOEFL_01027	8.62e-271	essB	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
MDKIOEFL_01028	0.0	essC	-	-	D	ko:K03466	-	ko00000,ko03036	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MDKIOEFL_01029	0.0	yueB	-	-	S	-	-	-	type VII secretion protein EsaA
MDKIOEFL_01030	6.96e-94	yueC	-	-	S	-	-	-	Family of unknown function (DUF5383)
MDKIOEFL_01031	2.68e-100	yueD	1.1.1.320	-	IQ	ko:K16216	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MDKIOEFL_01032	1.57e-124	yueE	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
MDKIOEFL_01033	8.4e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF2642)
MDKIOEFL_01034	3.82e-91	-	-	-	S	-	-	-	Protein of unknown function (DUF2283)
MDKIOEFL_01035	1.35e-244	yueF	-	-	S	-	-	-	transporter activity
MDKIOEFL_01036	1.19e-41	yueG	-	-	S	ko:K06299	-	ko00000	Spore germination protein gerPA/gerPF
MDKIOEFL_01037	1.63e-52	yueH	-	-	S	-	-	-	YueH-like protein
MDKIOEFL_01038	3.64e-86	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
MDKIOEFL_01039	7.71e-133	pncA	-	-	Q	ko:K16788	-	ko00000,ko02000	COG1335 Amidases related to nicotinamidase
MDKIOEFL_01040	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MDKIOEFL_01041	2.92e-298	yuxH	-	-	T	-	-	-	signal transduction protein containing EAL and modified HD-GYP domains
MDKIOEFL_01042	4.38e-09	yuzC	-	-	-	-	-	-	-
MDKIOEFL_01043	6.29e-10	-	-	-	S	-	-	-	DegQ (SacQ) family
MDKIOEFL_01044	8.19e-169	comQ	-	-	H	ko:K02251	ko02024,map02024	ko00000,ko00001,ko02044	Belongs to the FPP GGPP synthase family
MDKIOEFL_01046	0.0	comP	2.7.13.3	-	T	ko:K07680	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MDKIOEFL_01047	2.06e-150	comA	-	-	K	ko:K07691	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MDKIOEFL_01048	1.58e-82	yuxO	-	-	Q	-	-	-	protein, possibly involved in aromatic compounds catabolism
MDKIOEFL_01049	8.49e-79	mrpG	-	-	P	ko:K05571	-	ko00000,ko02000	COG1320 Multisubunit Na H antiporter, MnhG subunit
MDKIOEFL_01050	2.23e-51	mrpF	-	-	P	ko:K05570	-	ko00000,ko02000	Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MDKIOEFL_01051	2.12e-102	mrpE	-	-	P	ko:K05569	-	ko00000,ko02000	Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MDKIOEFL_01052	0.0	mrpD	-	-	CP	ko:K05568	-	ko00000,ko02000	Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MDKIOEFL_01053	1.72e-66	mrpC	-	-	P	ko:K05567	-	ko00000,ko02000	Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MDKIOEFL_01054	7.66e-91	mrpB	-	-	P	ko:K05566	-	ko00000,ko02000	Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MDKIOEFL_01055	0.0	mrpA	-	-	CP	ko:K05565	-	ko00000,ko02000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MDKIOEFL_01056	1.73e-22	-	-	-	-	-	-	-	-
MDKIOEFL_01057	7.99e-309	malP	-	-	C	ko:K11616	ko02020,map02020	ko00000,ko00001	COG3493 Na citrate symporter
MDKIOEFL_01058	1.71e-215	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MDKIOEFL_01059	1.29e-236	yufP	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MDKIOEFL_01060	0.0	yufO	3.6.3.17	-	S	ko:K02056	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MDKIOEFL_01061	1.84e-246	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC-type transport system, periplasmic component surface lipoprotein
MDKIOEFL_01062	3.26e-162	dcuR	-	-	T	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
MDKIOEFL_01063	0.0	malK	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
MDKIOEFL_01064	4.19e-113	yufK	-	-	S	-	-	-	Family of unknown function (DUF5366)
MDKIOEFL_01065	1.92e-97	yuxK	-	-	S	-	-	-	protein conserved in bacteria
MDKIOEFL_01066	0.0	pbpD	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555,ko:K18770	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin-binding Protein
MDKIOEFL_01067	4.61e-244	yuxJ	-	-	EGP	-	-	-	Major facilitator superfamily
MDKIOEFL_01069	1.71e-149	kapD	-	-	L	ko:K06348	-	ko00000	the KinA pathway to sporulation
MDKIOEFL_01070	2.49e-91	kapB	-	-	G	ko:K06347	ko02020,map02020	ko00000,ko00001	Kinase associated protein B
MDKIOEFL_01071	3.54e-295	kinB2	2.7.13.3	-	T	ko:K07697	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MDKIOEFL_01072	1.65e-286	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
MDKIOEFL_01073	8.84e-52	yugE	-	-	S	-	-	-	Domain of unknown function (DUF1871)
MDKIOEFL_01074	6.68e-199	yugF	-	-	I	-	-	-	Hydrolase
MDKIOEFL_01075	6.74e-112	alaR	-	-	K	-	-	-	Transcriptional regulator
MDKIOEFL_01076	2.21e-254	yugH	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Aminotransferase
MDKIOEFL_01077	5e-83	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
MDKIOEFL_01078	2.21e-46	yuzA	-	-	S	ko:K09779	-	ko00000	Domain of unknown function (DUF378)
MDKIOEFL_01079	8.16e-287	yugJ	-	-	C	ko:K19955	-	ko00000,ko01000	oxidoreductases, Fe-dependent alcohol dehydrogenase family
MDKIOEFL_01080	9.22e-290	yugK	-	-	C	ko:K19955	-	ko00000,ko01000	Dehydrogenase
MDKIOEFL_01081	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
MDKIOEFL_01083	4.22e-95	yugN	-	-	S	-	-	-	YugN-like family
MDKIOEFL_01084	2.06e-232	yugO	-	-	P	ko:K10716	-	ko00000,ko02000	COG1226 Kef-type K transport systems
MDKIOEFL_01085	5.01e-69	mstX	-	-	S	-	-	-	Membrane-integrating protein Mistic
MDKIOEFL_01086	1.58e-50	-	-	-	-	-	-	-	-
MDKIOEFL_01087	4.8e-150	yugP	-	-	S	ko:K06973	-	ko00000	Zn-dependent protease
MDKIOEFL_01088	2.52e-300	yugS	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
MDKIOEFL_01089	0.0	yugT	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
MDKIOEFL_01090	3.63e-95	yugU	-	-	S	-	-	-	Uncharacterised protein family UPF0047
MDKIOEFL_01091	1.44e-47	-	-	-	-	-	-	-	-
MDKIOEFL_01092	6.15e-181	tgl	2.3.2.13	-	H	ko:K00686	-	ko00000,ko01000	Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
MDKIOEFL_01093	0.0	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MDKIOEFL_01094	1.14e-295	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MDKIOEFL_01095	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MDKIOEFL_01096	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MDKIOEFL_01097	0.0	yuxG	-	-	IQ	-	-	-	Class II Aldolase and Adducin N-terminal domain
MDKIOEFL_01098	1.42e-172	yulB	-	-	K	ko:K02530,ko:K22103	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
MDKIOEFL_01099	0.0	rhaB	2.7.1.5	-	G	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
MDKIOEFL_01100	2.86e-72	rhaM	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Involved in the anomeric conversion of L-rhamnose
MDKIOEFL_01101	0.0	rhaA	2.7.1.5, 5.3.1.14	-	G	ko:K00848,ko:K01813	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Belongs to the rhamnose isomerase family
MDKIOEFL_01102	1.06e-234	yulF	-	-	S	ko:K22230	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
MDKIOEFL_01103	1.55e-255	yubA	-	-	S	-	-	-	transporter activity
MDKIOEFL_01104	1.73e-182	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MDKIOEFL_01106	6.82e-114	cdoA	1.13.11.20	-	S	ko:K00456	ko00270,ko00430,ko01100,map00270,map00430,map01100	ko00000,ko00001,ko01000	Cysteine dioxygenase type I
MDKIOEFL_01107	0.0	yubD	-	-	P	-	-	-	Major Facilitator Superfamily
MDKIOEFL_01108	8.86e-195	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MDKIOEFL_01109	3.31e-52	yubF	-	-	S	-	-	-	yiaA/B two helix domain
MDKIOEFL_01110	4.17e-298	-	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium
MDKIOEFL_01111	1.06e-156	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
MDKIOEFL_01112	5.83e-118	yuaB	-	-	-	-	-	-	-
MDKIOEFL_01113	2.39e-121	yuaC	-	-	K	ko:K22109	-	ko00000,ko03000	Belongs to the GbsR family
MDKIOEFL_01114	0.0	gbsA	1.2.1.8	-	C	ko:K00130	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MDKIOEFL_01115	1e-290	gbsB	1.1.1.1	-	C	ko:K11440	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
MDKIOEFL_01116	5.8e-137	yuaD	-	-	-	-	-	-	-
MDKIOEFL_01117	1.95e-109	yuaE	-	-	S	-	-	-	DinB superfamily
MDKIOEFL_01118	1.68e-109	yuaF	-	-	OU	-	-	-	Membrane protein implicated in regulation of membrane protease activity
MDKIOEFL_01119	4.54e-258	yuaG	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	protein conserved in bacteria
MDKIOEFL_01120	1.64e-120	-	-	-	M	-	-	-	FR47-like protein
MDKIOEFL_01121	2.52e-122	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
MDKIOEFL_01122	5.3e-49	bofA	-	-	S	ko:K06317	-	ko00000	Sigma-K factor-processing regulatory protein BofA
MDKIOEFL_01123	1.55e-42	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
MDKIOEFL_01124	8.53e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MDKIOEFL_01125	8.75e-55	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MDKIOEFL_01126	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MDKIOEFL_01127	1.05e-108	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MDKIOEFL_01128	1.89e-123	yaaI	-	-	Q	-	-	-	COG1335 Amidases related to nicotinamidase
MDKIOEFL_01129	2.99e-275	yaaH	-	-	M	ko:K06306	-	ko00000	Glycoside Hydrolase Family
MDKIOEFL_01130	5.73e-149	dgk	2.7.1.113	-	F	ko:K15518	ko00230,map00230	ko00000,ko00001,ko01000	Deoxyguanosine kinase
MDKIOEFL_01131	3.72e-159	dck	2.7.1.74, 2.7.1.76	-	F	ko:K15519	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko01000	Deoxycytidine kinase
MDKIOEFL_01133	9.79e-296	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MDKIOEFL_01134	3.9e-137	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MDKIOEFL_01135	3.7e-202	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MDKIOEFL_01136	3.75e-316	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MDKIOEFL_01137	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MDKIOEFL_01138	4.23e-231	yaaC	-	-	S	-	-	-	YaaC-like Protein
MDKIOEFL_01139	8.72e-100	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
MDKIOEFL_01140	7.74e-257	mcsB	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
MDKIOEFL_01141	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
MDKIOEFL_01142	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MDKIOEFL_01143	3.8e-251	disA	2.7.7.85	-	L	ko:K07067	-	ko00000,ko01000	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
MDKIOEFL_01144	2.57e-252	yacL	-	-	S	-	-	-	COG4956 Integral membrane protein (PIN domain superfamily)
MDKIOEFL_01145	2.48e-160	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MDKIOEFL_01146	1.05e-111	ispF	2.7.7.60, 4.6.1.12	-	I	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MDKIOEFL_01147	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MDKIOEFL_01148	1.91e-152	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase
MDKIOEFL_01149	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MDKIOEFL_01150	2.04e-95	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MDKIOEFL_01151	3.52e-173	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MDKIOEFL_01152	3.31e-114	yacP	-	-	S	ko:K06962	-	ko00000	RNA-binding protein containing a PIN domain
MDKIOEFL_01153	3.27e-149	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
MDKIOEFL_01154	2.65e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MDKIOEFL_01155	1.37e-124	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
MDKIOEFL_01156	3.4e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MDKIOEFL_01157	1.82e-162	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MDKIOEFL_01158	4.03e-104	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MDKIOEFL_01159	2.84e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MDKIOEFL_01160	5.1e-140	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
MDKIOEFL_01161	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MDKIOEFL_01162	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MDKIOEFL_01163	1.99e-44	rplGB	-	-	J	ko:K07590	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the eukaryotic ribosomal protein eL8 family
MDKIOEFL_01164	6.67e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MDKIOEFL_01165	4.85e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MDKIOEFL_01166	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MDKIOEFL_01167	2.01e-287	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MDKIOEFL_01168	4.3e-229	ybaC	-	-	S	-	-	-	Alpha/beta hydrolase family
MDKIOEFL_01169	2.58e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
MDKIOEFL_01170	7.2e-144	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MDKIOEFL_01171	7.98e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
MDKIOEFL_01172	3.27e-58	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MDKIOEFL_01173	2.72e-200	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MDKIOEFL_01174	2.83e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MDKIOEFL_01175	9.23e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MDKIOEFL_01176	5.9e-152	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MDKIOEFL_01177	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MDKIOEFL_01178	1.88e-35	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
MDKIOEFL_01179	1.64e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MDKIOEFL_01180	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MDKIOEFL_01181	1.43e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MDKIOEFL_01182	7.72e-122	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MDKIOEFL_01183	1.43e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MDKIOEFL_01184	3.11e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MDKIOEFL_01185	4.47e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MDKIOEFL_01186	2.89e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MDKIOEFL_01187	9.16e-111	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MDKIOEFL_01188	1.59e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
MDKIOEFL_01189	7.32e-95	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
MDKIOEFL_01190	5.7e-298	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MDKIOEFL_01191	2.51e-157	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MDKIOEFL_01192	2.32e-182	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
MDKIOEFL_01193	2.92e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MDKIOEFL_01194	2.45e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
MDKIOEFL_01195	1.09e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MDKIOEFL_01196	3.24e-84	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MDKIOEFL_01197	7.01e-217	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MDKIOEFL_01198	4.27e-77	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
MDKIOEFL_01199	7.5e-200	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MDKIOEFL_01200	1.28e-195	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MDKIOEFL_01201	1.6e-177	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MDKIOEFL_01202	6.15e-182	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MDKIOEFL_01203	1.13e-102	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MDKIOEFL_01204	4.28e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
MDKIOEFL_01205	2.06e-184	ybaJ	-	-	Q	-	-	-	Methyltransferase domain
MDKIOEFL_01206	5.12e-91	ybaK	-	-	S	-	-	-	Protein of unknown function (DUF2521)
MDKIOEFL_01207	9.05e-170	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
MDKIOEFL_01208	1.1e-255	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MDKIOEFL_01209	1.04e-122	gerD	-	-	-	ko:K06294	-	ko00000	-
MDKIOEFL_01210	4.89e-132	kbaA	-	-	S	ko:K06349	-	ko00000	Involved in the activation of the KinB signaling pathway of sporulation
MDKIOEFL_01211	8.69e-181	pdaB	-	-	G	-	-	-	Polysaccharide deacetylase
MDKIOEFL_01222	1.23e-182	spo0M	-	-	S	ko:K06377	-	ko00000	COG4326 Sporulation control protein
MDKIOEFL_01223	1.58e-36	-	-	-	-	-	-	-	-
MDKIOEFL_01224	3.89e-137	ygaJ	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
MDKIOEFL_01225	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MDKIOEFL_01227	0.0	katA	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
MDKIOEFL_01228	9.01e-179	ssuB	-	-	P	ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
MDKIOEFL_01229	4.19e-218	ssuA	-	-	M	ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Sulfonate ABC transporter
MDKIOEFL_01230	5.86e-190	ssuC	-	-	P	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MDKIOEFL_01231	9.35e-276	ssuD	1.14.14.28, 1.14.14.5	-	C	ko:K04091,ko:K20938	ko00920,map00920	ko00000,ko00001,ko01000	Catalyzes the desulfonation of aliphatic sulfonates
MDKIOEFL_01233	4.82e-55	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MDKIOEFL_01234	7.69e-100	ygaO	-	-	-	-	-	-	-
MDKIOEFL_01235	1.48e-39	-	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional regulator
MDKIOEFL_01237	6.43e-146	yhzB	-	-	S	-	-	-	B3/4 domain
MDKIOEFL_01238	1.2e-283	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MDKIOEFL_01239	2.77e-225	yhbB	-	-	S	-	-	-	Putative amidase domain
MDKIOEFL_01240	6.53e-113	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MDKIOEFL_01241	3.4e-143	yhbD	-	-	K	-	-	-	Protein of unknown function (DUF4004)
MDKIOEFL_01242	1.32e-95	yhbE	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
MDKIOEFL_01243	9.07e-107	yhbF	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
MDKIOEFL_01244	0.0	prkA	-	-	T	ko:K07180	-	ko00000	Ser protein kinase
MDKIOEFL_01245	1.21e-286	yhbH	-	-	S	ko:K09786	-	ko00000	Belongs to the UPF0229 family
MDKIOEFL_01246	1.29e-101	yhbI	-	-	K	ko:K15973	-	ko00000,ko03000	DNA-binding transcription factor activity
MDKIOEFL_01247	2.67e-133	yhbJ	-	-	V	-	-	-	COG1566 Multidrug resistance efflux pump
MDKIOEFL_01248	0.0	yhcA	-	-	EGP	ko:K03446	-	ko00000,ko00002,ko02000	the major facilitator superfamily
MDKIOEFL_01249	4.87e-128	yhcB	1.6.5.2	-	S	ko:K03809	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	Belongs to the WrbA family
MDKIOEFL_01250	3.95e-59	yhcC	-	-	-	-	-	-	-
MDKIOEFL_01251	2.06e-69	-	-	-	-	-	-	-	-
MDKIOEFL_01252	1.67e-79	yhcF	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator
MDKIOEFL_01253	3.24e-156	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MDKIOEFL_01254	2.95e-209	yhcH	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MDKIOEFL_01255	1.15e-210	yhcI	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MDKIOEFL_01256	1.91e-42	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
MDKIOEFL_01257	4.49e-194	metQ_3	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
MDKIOEFL_01258	3.36e-249	yhcK	2.7.7.65	-	T	ko:K18967	-	ko00000,ko01000,ko02000	COG2199 FOG GGDEF domain
MDKIOEFL_01259	2.62e-301	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MDKIOEFL_01260	1.19e-114	-	-	-	S	-	-	-	Protein of unknown function (DUF2812)
MDKIOEFL_01261	3.22e-65	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
MDKIOEFL_01262	1.09e-61	yhcM	-	-	-	-	-	-	-
MDKIOEFL_01263	9.32e-108	yhcN	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MDKIOEFL_01264	2.67e-225	yhcP	-	-	-	-	-	-	-
MDKIOEFL_01265	1.68e-146	yhcQ	-	-	M	-	-	-	Spore coat protein
MDKIOEFL_01266	0.0	yhcR	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01081,ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MDKIOEFL_01267	5.1e-134	yhcS	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
MDKIOEFL_01268	4.78e-218	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
MDKIOEFL_01269	4.27e-89	yhcU	-	-	S	-	-	-	Family of unknown function (DUF5365)
MDKIOEFL_01270	1.76e-90	yhcV	-	-	S	-	-	-	COG0517 FOG CBS domain
MDKIOEFL_01271	2.5e-154	yhcW	-	-	S	ko:K07025	-	ko00000	hydrolase
MDKIOEFL_01272	0.0	yhcX	-	-	K	-	-	-	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MDKIOEFL_01273	0.0	yhxA	-	-	E	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MDKIOEFL_01274	5.35e-135	glpP	-	-	K	ko:K02443	-	ko00000,ko03000	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MDKIOEFL_01275	5.7e-196	glpF	-	-	G	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
MDKIOEFL_01276	0.0	glpK	2.7.1.30	-	C	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MDKIOEFL_01277	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MDKIOEFL_01278	0.0	pgcA	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase
MDKIOEFL_01279	2.56e-270	yhcY	2.7.13.3	-	T	ko:K02480	-	ko00000,ko01000,ko01001,ko02022	Histidine kinase
MDKIOEFL_01280	7.73e-144	yhcZ	-	-	K	ko:K02479	-	ko00000,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MDKIOEFL_01281	1.63e-116	yhdA	1.7.1.6	-	S	ko:K03206	-	ko00000,ko01000	NADPH-dependent FMN reductase
MDKIOEFL_01282	1.65e-51	yhdB	-	-	S	-	-	-	YhdB-like protein
MDKIOEFL_01283	1.02e-71	yhdC	-	-	S	-	-	-	Protein of unknown function (DUF3889)
MDKIOEFL_01284	2.79e-274	lytF	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
MDKIOEFL_01285	1.95e-99	nsrR	-	-	K	ko:K13771	ko05132,map05132	ko00000,ko00001,ko03000	Transcriptional regulator
MDKIOEFL_01286	1.44e-304	ygxB	-	-	M	-	-	-	Conserved TM helix
MDKIOEFL_01287	0.0	spoVR	-	-	S	ko:K06415	-	ko00000	Stage V sporulation protein R
MDKIOEFL_01288	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
MDKIOEFL_01289	1.45e-203	lytE	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
MDKIOEFL_01290	4.93e-210	citR	-	-	K	ko:K19242	-	ko00000,ko03000	Transcriptional regulator
MDKIOEFL_01291	7.18e-259	citA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
MDKIOEFL_01292	4.53e-205	yhdF	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MDKIOEFL_01293	7.15e-316	yhdG	-	-	E	ko:K03294	-	ko00000	amino acid
MDKIOEFL_01294	2.04e-308	yhdH	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MDKIOEFL_01295	0.0	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MDKIOEFL_01296	1.75e-100	-	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MDKIOEFL_01297	4.27e-59	yhdK	-	-	S	-	-	-	Sigma-M inhibitor protein
MDKIOEFL_01298	6.13e-258	yhdL	-	-	S	-	-	-	Sigma factor regulator N-terminal
MDKIOEFL_01299	3.24e-113	sigM	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MDKIOEFL_01300	1.56e-40	yhdN	-	-	C	-	-	-	Aldo keto reductase
MDKIOEFL_01301	6.82e-160	yhdN	-	-	C	-	-	-	Aldo keto reductase
MDKIOEFL_01302	3.9e-143	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MDKIOEFL_01303	2.18e-304	yhdP	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
MDKIOEFL_01304	3.44e-97	cueR	-	-	K	ko:K11923	-	ko00000,ko03000	transcriptional
MDKIOEFL_01305	1.7e-282	yhdR	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
MDKIOEFL_01306	0.0	yhdT	-	-	P	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
MDKIOEFL_01307	4.81e-64	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MDKIOEFL_01308	1.18e-86	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MDKIOEFL_01309	2.59e-172	yhdW	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
MDKIOEFL_01310	3.7e-09	yhdX	-	-	S	-	-	-	Uncharacterized protein YhdX
MDKIOEFL_01311	9.73e-239	yhdY	-	-	M	ko:K16052	-	ko00000,ko02000	Mechanosensitive ion channel
MDKIOEFL_01312	1.63e-177	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
MDKIOEFL_01313	3.54e-194	nodB1	-	-	G	-	-	-	deacetylase
MDKIOEFL_01314	1.1e-195	dat	2.6.1.21	-	E	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
MDKIOEFL_01315	2.43e-301	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
MDKIOEFL_01316	1.53e-108	nhaX	-	-	T	-	-	-	Belongs to the universal stress protein A family
MDKIOEFL_01317	0.0	yheI	-	-	V	ko:K18216,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
MDKIOEFL_01318	0.0	yheH	-	-	V	ko:K06147,ko:K18217,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
MDKIOEFL_01319	1.29e-140	yheG	-	-	GM	-	-	-	NAD(P)H-binding
MDKIOEFL_01320	1.25e-38	sspB	-	-	S	ko:K06418,ko:K06419,ko:K06420	-	ko00000	spore protein
MDKIOEFL_01321	2.27e-49	yheE	-	-	S	-	-	-	Family of unknown function (DUF5342)
MDKIOEFL_01322	0.0	yheD	-	-	HJ	-	-	-	YheC/D like ATP-grasp
MDKIOEFL_01323	1.32e-273	yheC	-	-	HJ	-	-	-	YheC/D like ATP-grasp
MDKIOEFL_01324	7.19e-260	yheB	-	-	S	-	-	-	Belongs to the UPF0754 family
MDKIOEFL_01325	7.46e-72	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
MDKIOEFL_01326	1.29e-261	yhaZ	-	-	L	-	-	-	DNA alkylation repair enzyme
MDKIOEFL_01327	8.7e-198	yhaX	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
MDKIOEFL_01328	0.0	hemZ	-	-	H	-	-	-	coproporphyrinogen III oxidase
MDKIOEFL_01329	1.85e-267	yhaU	-	-	P	ko:K03455	-	ko00000	COG0475 Kef-type K transport systems, membrane components
MDKIOEFL_01330	6.51e-114	-	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
MDKIOEFL_01332	1.79e-169	yhaR	-	-	I	-	-	-	enoyl-CoA hydratase
MDKIOEFL_01333	5.43e-35	-	-	-	S	-	-	-	YhzD-like protein
MDKIOEFL_01334	4.57e-214	yhaQ	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MDKIOEFL_01335	5.14e-272	yhaP	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	COG1668 ABC-type Na efflux pump, permease component
MDKIOEFL_01336	1.57e-299	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	DNA repair exonuclease
MDKIOEFL_01337	0.0	yhaN	-	-	L	-	-	-	AAA domain
MDKIOEFL_01338	5.22e-228	yhaM	-	-	L	ko:K03698	-	ko00000,ko01000,ko03019	Shows a 3'-5' exoribonuclease activity
MDKIOEFL_01339	1.88e-39	yhaL	-	-	S	-	-	-	Sporulation protein YhaL
MDKIOEFL_01340	2.14e-170	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MDKIOEFL_01341	1.4e-116	yhaK	-	-	S	-	-	-	Putative zincin peptidase
MDKIOEFL_01342	3.46e-72	yhaI	-	-	S	-	-	-	Protein of unknown function (DUF1878)
MDKIOEFL_01343	4.92e-148	hpr	-	-	K	ko:K09682	-	ko00000,ko03000	Negative regulator of protease production and sporulation
MDKIOEFL_01344	3.89e-54	yhaH	-	-	S	-	-	-	YtxH-like protein
MDKIOEFL_01345	9.66e-30	-	-	-	-	-	-	-	-
MDKIOEFL_01346	6.32e-104	trpP	-	-	S	-	-	-	Tryptophan transporter TrpP
MDKIOEFL_01347	7.5e-262	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MDKIOEFL_01348	3.5e-106	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
MDKIOEFL_01349	6.35e-175	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	transporter (ATP-binding protein)
MDKIOEFL_01350	1.41e-268	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
MDKIOEFL_01351	3.37e-160	ecsC	-	-	S	-	-	-	EcsC protein family
MDKIOEFL_01352	1.04e-289	yhaA	-	-	E	ko:K01436	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
MDKIOEFL_01353	4.67e-313	yhfA	-	-	C	-	-	-	membrane
MDKIOEFL_01354	1e-44	-	-	-	C	-	-	-	Rubrerythrin
MDKIOEFL_01355	1.31e-118	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
MDKIOEFL_01356	0.0	pbpF	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
MDKIOEFL_01357	2.14e-258	hemE	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MDKIOEFL_01358	3.99e-230	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
MDKIOEFL_01359	0.0	hemY	1.3.3.15, 1.3.3.4	-	H	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MDKIOEFL_01360	5.79e-132	yhgD	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
MDKIOEFL_01361	0.0	yhgE	-	-	S	ko:K01421	-	ko00000	YhgE Pip N-terminal domain protein
MDKIOEFL_01362	8.77e-237	fabHB	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MDKIOEFL_01363	2.2e-176	yhfC	-	-	S	-	-	-	Putative membrane peptidase family (DUF2324)
MDKIOEFL_01364	1.55e-252	yhfE	-	-	G	-	-	-	peptidase M42
MDKIOEFL_01365	1.79e-92	-	-	-	S	-	-	-	ASCH
MDKIOEFL_01366	4.77e-289	gltT	-	-	C	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MDKIOEFL_01367	5.93e-183	yhfI	-	-	S	-	-	-	COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
MDKIOEFL_01368	2.86e-245	lplJ	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
MDKIOEFL_01369	2.48e-142	yhfK	-	-	GM	-	-	-	NmrA-like family
MDKIOEFL_01370	0.0	yhfL	6.2.1.3	-	IQ	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
MDKIOEFL_01371	2.28e-84	yhfM	-	-	-	-	-	-	-
MDKIOEFL_01372	4.58e-306	yhfN	-	-	O	-	-	-	Peptidase M48
MDKIOEFL_01373	6.91e-260	aprE	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MDKIOEFL_01374	2.09e-100	-	-	-	K	-	-	-	acetyltransferase
MDKIOEFL_01375	2.4e-232	yhfP	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Quinone oxidoreductase
MDKIOEFL_01376	7.94e-223	yhfQ	-	-	M	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
MDKIOEFL_01377	3.23e-139	yhfR	5.4.2.12	-	G	ko:K15634,ko:K15640	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphoglycerate mutase family
MDKIOEFL_01378	1.05e-250	yhfS	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
MDKIOEFL_01379	0.0	vraA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
MDKIOEFL_01380	1.47e-118	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
MDKIOEFL_01381	7.51e-260	hemAT	-	-	NT	ko:K06595	-	ko00000,ko02035	chemotaxis protein
MDKIOEFL_01382	0.0	yhfW	-	-	CE	-	-	-	COG0665 Glycine D-amino acid oxidases (deaminating)
MDKIOEFL_01383	2.24e-203	yhxC	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MDKIOEFL_01384	9.84e-45	yhzC	-	-	S	-	-	-	IDEAL
MDKIOEFL_01385	6.29e-141	comK	-	-	K	ko:K02250	ko02024,map02024	ko00000,ko00001,ko02044,ko03000	Competence transcription factor
MDKIOEFL_01386	2.1e-215	yhxD	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
MDKIOEFL_01387	8.32e-56	yhjA	-	-	S	-	-	-	Excalibur calcium-binding domain
MDKIOEFL_01388	0.0	yhjB	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MDKIOEFL_01389	1.61e-36	yhjC	-	-	S	-	-	-	Protein of unknown function (DUF3311)
MDKIOEFL_01390	4.13e-78	yhjD	-	-	-	-	-	-	-
MDKIOEFL_01391	4.87e-141	yhjE	-	-	S	-	-	-	SNARE associated Golgi protein
MDKIOEFL_01392	3.09e-118	spsB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MDKIOEFL_01393	0.0	yhjG	-	-	CH	-	-	-	FAD binding domain
MDKIOEFL_01394	2.82e-122	yhjH	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MDKIOEFL_01397	3.13e-272	glcP	-	-	G	ko:K08174	-	ko00000,ko02000	Major Facilitator Superfamily
MDKIOEFL_01398	1.14e-256	-	1.1.1.18, 1.1.1.361, 1.1.1.369	-	S	ko:K00010,ko:K18652	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
MDKIOEFL_01399	1.07e-204	ntdB	3.1.3.24, 3.1.3.92	-	S	ko:K07024,ko:K18654	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose-6F-phosphate phosphohydrolase
MDKIOEFL_01400	0.0	-	2.6.1.104	-	E	ko:K18653	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
MDKIOEFL_01401	1.46e-237	yhjM	-	-	K	-	-	-	Transcriptional regulator
MDKIOEFL_01402	1.19e-257	yhjN	-	-	S	ko:K07120	-	ko00000	membrane
MDKIOEFL_01403	7.19e-263	-	-	-	EGP	-	-	-	Transmembrane secretion effector
MDKIOEFL_01404	0.0	-	-	-	S	-	-	-	Sugar transport-related sRNA regulator N-term
MDKIOEFL_01405	3.54e-77	yhjQ	-	-	C	-	-	-	COG1145 Ferredoxin
MDKIOEFL_01406	5.17e-99	yhjR	-	-	S	-	-	-	Rubrerythrin
MDKIOEFL_01407	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	ATP-dependent helicase deoxyribonuclease subunit B
MDKIOEFL_01408	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
MDKIOEFL_01409	1.98e-280	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MDKIOEFL_01410	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	COG0419 ATPase involved in DNA repair
MDKIOEFL_01411	6.4e-65	yisB	-	-	V	-	-	-	COG1403 Restriction endonuclease
MDKIOEFL_01412	3.3e-43	gerPF	-	-	S	ko:K06299,ko:K06304	-	ko00000	Spore germination protein gerPA/gerPF
MDKIOEFL_01413	1.12e-85	gerPE	-	-	S	ko:K06303	-	ko00000	Spore germination protein GerPE
MDKIOEFL_01414	6.07e-33	gerPD	-	-	S	ko:K06302	-	ko00000	Spore germination protein
MDKIOEFL_01415	3.34e-92	gerPC	-	-	S	ko:K06301	-	ko00000	Spore germination protein
MDKIOEFL_01416	3.87e-42	gerPB	-	-	S	ko:K06300	-	ko00000	cell differentiation
MDKIOEFL_01417	1.82e-45	gerPA	-	-	S	ko:K06299	-	ko00000	Spore germination protein
MDKIOEFL_01418	1.52e-32	yisI	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
MDKIOEFL_01419	4.62e-223	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
MDKIOEFL_01420	2.66e-219	yisK	-	-	Q	-	-	-	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
MDKIOEFL_01421	1.02e-74	yisL	-	-	S	-	-	-	UPF0344 protein
MDKIOEFL_01422	0.0	wprA	-	-	O	ko:K13274	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MDKIOEFL_01423	3.02e-131	yisN	-	-	S	-	-	-	Protein of unknown function (DUF2777)
MDKIOEFL_01424	0.0	asnO	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
MDKIOEFL_01425	1.07e-114	yizA	-	-	S	-	-	-	Damage-inducible protein DinB
MDKIOEFL_01426	1.42e-185	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	phytoene
MDKIOEFL_01427	1.01e-310	yisQ	-	-	V	-	-	-	Mate efflux family protein
MDKIOEFL_01428	1.41e-207	yisR	-	-	K	-	-	-	Transcriptional regulator
MDKIOEFL_01429	1.83e-235	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MDKIOEFL_01430	4.25e-248	yisS	1.1.1.18, 1.1.1.369, 1.1.1.370	-	S	ko:K00010,ko:K16043	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
MDKIOEFL_01431	1.65e-118	yisT	-	-	S	-	-	-	DinB family
MDKIOEFL_01432	2.37e-134	argO	-	-	S	ko:K06895	-	ko00000,ko02000	Lysine exporter protein LysE YggA
MDKIOEFL_01433	1.79e-164	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MDKIOEFL_01434	4.76e-146	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MDKIOEFL_01435	1.24e-95	yisX	-	-	S	-	-	-	Pentapeptide repeats (9 copies)
MDKIOEFL_01436	3.73e-198	yisY	1.11.1.10	-	I	ko:K00433	-	ko00000,ko01000	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MDKIOEFL_01437	4.06e-145	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
MDKIOEFL_01438	6.53e-294	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
MDKIOEFL_01439	4.35e-181	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
MDKIOEFL_01440	1.88e-153	-	3.1.3.71	-	H	ko:K05979	ko00680,ko01120,map00680,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the ComB family
MDKIOEFL_01441	7.15e-179	yitD	4.4.1.19	-	S	ko:K08097	ko00680,ko01120,map00680,map01120	ko00000,ko00001,ko00002,ko01000	synthase
MDKIOEFL_01442	6.77e-145	yitE	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MDKIOEFL_01443	6.13e-283	yitF	5.5.1.27	-	M	ko:K18983	ko00053,map00053	ko00000,ko00001,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
MDKIOEFL_01444	8.28e-291	yitG	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MDKIOEFL_01445	3.69e-196	yitH	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MDKIOEFL_01446	7.23e-92	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
MDKIOEFL_01447	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
MDKIOEFL_01448	1.75e-76	yitK	-	-	S	ko:K09767	-	ko00000	Belongs to the UPF0234 family
MDKIOEFL_01449	2.26e-203	yitL	-	-	S	ko:K00243	-	ko00000	protein conserved in bacteria
MDKIOEFL_01450	4.16e-122	-	-	-	-	-	-	-	-
MDKIOEFL_01451	1.42e-218	-	-	-	-	-	-	-	-
MDKIOEFL_01452	1.56e-125	-	-	-	S	-	-	-	Sporulation delaying protein SdpA
MDKIOEFL_01453	2.08e-77	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
MDKIOEFL_01454	5.02e-119	-	-	-	-	-	-	-	-
MDKIOEFL_01455	4.59e-59	yitR	-	-	S	-	-	-	Domain of unknown function (DUF3784)
MDKIOEFL_01456	0.0	nprB	3.4.24.28	-	E	ko:K01400,ko:K08777	ko02024,map02024	ko00000,ko00001,ko01000,ko01002	Peptidase M4
MDKIOEFL_01457	1.51e-200	yitS	-	-	S	-	-	-	protein conserved in bacteria
MDKIOEFL_01458	2.29e-189	yitT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MDKIOEFL_01459	1.96e-93	ipi	-	-	S	-	-	-	Intracellular proteinase inhibitor
MDKIOEFL_01460	1.01e-25	-	-	-	S	-	-	-	Protein of unknown function (DUF3813)
MDKIOEFL_01461	1.52e-198	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
MDKIOEFL_01462	1.02e-184	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
MDKIOEFL_01463	4.63e-68	yitW	-	-	S	-	-	-	metal-sulfur cluster biosynthetic enzyme
MDKIOEFL_01464	1.01e-30	-	-	-	S	-	-	-	Proteolipid membrane potential modulator
MDKIOEFL_01465	0.0	yitY	-	-	C	-	-	-	D-arabinono-1,4-lactone oxidase
MDKIOEFL_01466	3.24e-114	yitZ	-	-	G	-	-	-	Major Facilitator Superfamily
MDKIOEFL_01467	3.52e-253	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MDKIOEFL_01468	7.1e-293	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MDKIOEFL_01469	1.27e-175	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
MDKIOEFL_01470	9.37e-276	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
MDKIOEFL_01471	6.67e-262	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
MDKIOEFL_01472	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase ammonia chain
MDKIOEFL_01473	6.07e-225	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MDKIOEFL_01474	2.51e-39	yjzC	-	-	S	-	-	-	YjzC-like protein
MDKIOEFL_01475	2.17e-23	yjzD	-	-	S	-	-	-	Protein of unknown function (DUF2929)
MDKIOEFL_01476	2.42e-182	yjaU	-	-	I	-	-	-	carboxylic ester hydrolase activity
MDKIOEFL_01477	8.29e-129	yjaV	-	-	-	-	-	-	-
MDKIOEFL_01478	3.7e-234	med	-	-	S	ko:K05519,ko:K07335	-	ko00000,ko03000	Transcriptional activator protein med
MDKIOEFL_01479	1.07e-35	comZ	-	-	S	ko:K02254	-	ko00000,ko02044	ComZ
MDKIOEFL_01480	4.43e-30	yjzB	-	-	-	-	-	-	-
MDKIOEFL_01481	1.61e-221	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MDKIOEFL_01482	3.06e-302	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MDKIOEFL_01483	4.51e-191	yjaZ	-	-	O	-	-	-	Zn-dependent protease
MDKIOEFL_01484	3.56e-233	appD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MDKIOEFL_01485	2.42e-236	appF	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MDKIOEFL_01486	0.0	appA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
MDKIOEFL_01487	6.73e-216	appB	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MDKIOEFL_01488	3.64e-198	appC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MDKIOEFL_01489	3.18e-190	yjbA	-	-	S	-	-	-	Belongs to the UPF0736 family
MDKIOEFL_01490	1.24e-234	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
MDKIOEFL_01491	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MDKIOEFL_01492	3.44e-211	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MDKIOEFL_01493	1.07e-211	oppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MDKIOEFL_01494	3.22e-248	oppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MDKIOEFL_01495	1.27e-219	oppF	-	-	E	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MDKIOEFL_01496	7.88e-259	yjbB	-	-	EGP	-	-	-	Major Facilitator Superfamily
MDKIOEFL_01497	8.88e-132	yjbC	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MDKIOEFL_01498	1.01e-87	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MDKIOEFL_01499	7.1e-144	yjbE	-	-	P	-	-	-	Integral membrane protein TerC family
MDKIOEFL_01500	4.65e-149	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MDKIOEFL_01501	3.45e-279	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
MDKIOEFL_01502	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
MDKIOEFL_01503	2.68e-28	-	-	-	-	-	-	-	-
MDKIOEFL_01505	1.32e-218	yjbH	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
MDKIOEFL_01506	8.58e-94	yjbI	-	-	S	ko:K06886	-	ko00000	Bacterial-like globin
MDKIOEFL_01507	2.8e-126	yjbJ	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MDKIOEFL_01508	7.32e-130	yjbK	-	-	S	-	-	-	protein conserved in bacteria
MDKIOEFL_01509	1.87e-81	yjbL	-	-	S	-	-	-	Belongs to the UPF0738 family
MDKIOEFL_01510	5.06e-145	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	GTP pyrophosphokinase
MDKIOEFL_01511	2.94e-194	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MDKIOEFL_01512	1.49e-202	rluD	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
MDKIOEFL_01513	3.3e-180	prpE	3.1.3.16, 3.6.1.41	-	T	ko:K01090,ko:K01525	ko00230,map00230	ko00000,ko00001,ko01000	Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
MDKIOEFL_01514	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MDKIOEFL_01515	5.7e-177	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MDKIOEFL_01516	5.47e-137	tenI	5.3.99.10	-	H	ko:K10810	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Transcriptional regulator TenI
MDKIOEFL_01517	4.44e-275	thiO	1.4.3.19, 1.4.5.1	-	E	ko:K00285,ko:K03153	ko00360,ko00730,ko01100,map00360,map00730,map01100	ko00000,ko00001,ko01000	Glycine oxidase
MDKIOEFL_01518	8.9e-41	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	thiamine diphosphate biosynthetic process
MDKIOEFL_01519	6.78e-174	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
MDKIOEFL_01520	6.18e-238	thiF	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MDKIOEFL_01521	4.85e-191	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
MDKIOEFL_01522	1.23e-182	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
MDKIOEFL_01523	1.71e-102	yjbX	-	-	S	-	-	-	Spore coat protein
MDKIOEFL_01524	4.57e-108	cotZ	-	-	S	ko:K06344	-	ko00000	Spore coat protein
MDKIOEFL_01525	3.12e-124	cotY	-	-	S	ko:K06343	-	ko00000	Spore coat protein Z
MDKIOEFL_01526	3.55e-110	cotX	-	-	S	ko:K06342	-	ko00000	Spore Coat Protein X and V domain
MDKIOEFL_01527	1.08e-54	cotW	-	-	-	ko:K06341	-	ko00000	-
MDKIOEFL_01528	1.44e-72	cotV	-	-	S	ko:K06340	-	ko00000	Spore Coat Protein X and V domain
MDKIOEFL_01529	5.03e-75	yjcA	-	-	S	-	-	-	Protein of unknown function (DUF1360)
MDKIOEFL_01532	1.88e-52	spoVIF	-	-	S	-	-	-	Stage VI sporulation protein F
MDKIOEFL_01533	0.0	yjcD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
MDKIOEFL_01534	3.65e-50	-	-	-	-	-	-	-	-
MDKIOEFL_01535	7.75e-94	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MDKIOEFL_01536	1.2e-121	yjcG	-	-	J	-	-	-	Belongs to the 2H phosphoesterase superfamily. YjcG family
MDKIOEFL_01537	1.63e-178	yjcH	-	-	P	ko:K07214	-	ko00000	COG2382 Enterochelin esterase and related enzymes
MDKIOEFL_01538	1.98e-273	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
MDKIOEFL_01539	1.84e-280	metC	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
MDKIOEFL_01540	2.05e-127	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Alanine acetyltransferase
MDKIOEFL_01541	3.01e-273	yjcL	-	-	S	-	-	-	Protein of unknown function (DUF819)
MDKIOEFL_01543	1.26e-23	-	-	-	-	-	-	-	-
MDKIOEFL_01544	7.67e-50	-	-	-	-	-	-	-	-
MDKIOEFL_01546	5e-297	-	-	-	M	-	-	-	nucleic acid phosphodiester bond hydrolysis
MDKIOEFL_01550	4.81e-62	-	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
MDKIOEFL_01551	1.27e-61	yjcS	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
MDKIOEFL_01552	8.81e-61	yjcN	-	-	-	-	-	-	-
MDKIOEFL_01553	0.0	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	transcriptional antiterminator
MDKIOEFL_01554	0.0	manP	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MDKIOEFL_01555	4.19e-239	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
MDKIOEFL_01556	1.53e-74	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
MDKIOEFL_01557	1.03e-116	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
MDKIOEFL_01559	8.3e-105	ebsC	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MDKIOEFL_01560	6.12e-40	-	-	-	S	-	-	-	Domain of unknown function (DUF4177)
MDKIOEFL_01561	2.31e-69	yjdJ	-	-	S	-	-	-	Domain of unknown function (DUF4306)
MDKIOEFL_01562	3.07e-223	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MDKIOEFL_01564	0.0	yjeA	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
MDKIOEFL_01565	8.68e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF2690)
MDKIOEFL_01566	1.13e-29	yjfB	-	-	S	-	-	-	Putative motility protein
MDKIOEFL_01567	1.21e-214	yjfC	-	-	O	-	-	-	Predicted Zn-dependent protease (DUF2268)
MDKIOEFL_01568	1.38e-59	yjgA	-	-	T	-	-	-	Protein of unknown function (DUF2809)
MDKIOEFL_01569	5.79e-132	yjgB	-	-	S	-	-	-	Domain of unknown function (DUF4309)
MDKIOEFL_01570	0.0	yjgC	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase (NAD+) activity
MDKIOEFL_01571	1.6e-122	yjgD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
MDKIOEFL_01573	1.69e-143	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
MDKIOEFL_01575	6.72e-286	yjiB	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
MDKIOEFL_01576	2.92e-278	yjiC	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MDKIOEFL_01577	1.11e-41	-	-	-	-	-	-	-	-
MDKIOEFL_01578	8.69e-189	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
MDKIOEFL_01579	5.23e-155	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	transport system, permease component
MDKIOEFL_01580	2.3e-174	yjkB	-	-	P	ko:K02068	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MDKIOEFL_01581	8.95e-225	yjlA	-	-	EG	-	-	-	Putative multidrug resistance efflux transporter
MDKIOEFL_01582	4.08e-117	yjlB	-	-	S	-	-	-	Cupin domain
MDKIOEFL_01583	1.39e-87	yjlC	-	-	S	-	-	-	Protein of unknown function (DUF1641)
MDKIOEFL_01584	2.15e-280	yjlD	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
MDKIOEFL_01585	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
MDKIOEFL_01586	2.4e-311	-	-	-	G	ko:K03292	-	ko00000	symporter YjmB
MDKIOEFL_01587	8.13e-239	allD	1.1.1.350	-	C	ko:K00073	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000	Belongs to the LDH2 MDH2 oxidoreductase family
MDKIOEFL_01588	2.54e-243	yjmD	1.1.1.380	-	E	ko:K08322	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
MDKIOEFL_01589	9.24e-272	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
MDKIOEFL_01590	2.23e-195	yjmF	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
MDKIOEFL_01591	3.93e-289	exuT	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	Sugar (and other) transporter
MDKIOEFL_01592	1.15e-236	exuR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
MDKIOEFL_01593	0.0	uxaB	1.1.1.58	-	G	ko:K00041	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	tagaturonate reductase activity
MDKIOEFL_01594	0.0	uxaA	4.2.1.42, 4.2.1.7	-	G	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
MDKIOEFL_01595	4.56e-167	yjnA	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MDKIOEFL_01596	2.71e-103	yjoA	-	-	S	-	-	-	DinB family
MDKIOEFL_01597	1.75e-313	VCP	-	-	O	-	-	-	AAA domain (dynein-related subfamily)
MDKIOEFL_01598	8.59e-272	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
MDKIOEFL_01600	1.79e-55	-	-	-	S	-	-	-	YCII-related domain
MDKIOEFL_01601	1.26e-216	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
MDKIOEFL_01602	2.24e-79	yjqA	-	-	S	-	-	-	Bacterial PH domain
MDKIOEFL_01603	1.11e-138	yjqB	-	-	S	-	-	-	Pfam:DUF867
MDKIOEFL_01604	4.54e-204	yjqC	-	-	P	ko:K07217	-	ko00000	Catalase
MDKIOEFL_01605	1.79e-143	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
MDKIOEFL_01606	2.01e-74	xre	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MDKIOEFL_01608	1.07e-202	xkdB	-	-	K	-	-	-	sequence-specific DNA binding
MDKIOEFL_01609	7.48e-153	xkdC	-	-	L	-	-	-	Bacterial dnaA protein
MDKIOEFL_01613	7.79e-108	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
MDKIOEFL_01614	9.25e-177	xtmA	-	-	L	ko:K07474	-	ko00000	phage terminase small subunit
MDKIOEFL_01615	0.0	xtmB	-	-	S	ko:K06909	-	ko00000	phage terminase, large subunit
MDKIOEFL_01616	0.0	yqbA	-	-	S	-	-	-	portal protein
MDKIOEFL_01617	1.4e-176	xkdF3	-	-	L	-	-	-	Putative phage serine protease XkdF
MDKIOEFL_01618	3.91e-217	xkdG	-	-	S	-	-	-	Phage capsid family
MDKIOEFL_01619	1.63e-82	yqbG	-	-	S	-	-	-	Protein of unknown function (DUF3199)
MDKIOEFL_01620	1.44e-83	yqbH	-	-	S	-	-	-	Domain of unknown function (DUF3599)
MDKIOEFL_01621	2.38e-114	xkdI	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
MDKIOEFL_01622	2.87e-101	xkdJ	-	-	-	-	-	-	-
MDKIOEFL_01623	0.0	xkdK	-	-	S	-	-	-	Phage tail sheath C-terminal domain
MDKIOEFL_01624	6.01e-99	xkdM	-	-	S	-	-	-	Phage tail tube protein
MDKIOEFL_01625	9.21e-99	-	-	-	S	-	-	-	Phage XkdN-like tail assembly chaperone protein, TAC
MDKIOEFL_01647	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MDKIOEFL_01648	8.49e-265	glgC	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MDKIOEFL_01649	2.15e-237	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Glucose-1-phosphate adenylyltransferase, GlgD subunit
MDKIOEFL_01650	0.0	glgA	2.4.1.21	GT5	G	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
MDKIOEFL_01651	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MDKIOEFL_01652	1.9e-99	ytaB	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	membrane
MDKIOEFL_01653	1.29e-260	cotI	-	-	S	ko:K06331	-	ko00000	Spore coat protein
MDKIOEFL_01654	6.82e-274	cotSA	-	-	M	ko:K06338	-	ko00000	Glycosyl transferases group 1
MDKIOEFL_01655	2.82e-262	cotS	-	-	S	ko:K06337	-	ko00000	Seems to be required for the assembly of the CotSA protein in spores
MDKIOEFL_01657	6.86e-296	-	-	-	M	ko:K06338	-	ko00000	Glycosyltransferase Family 4
MDKIOEFL_01658	5.85e-226	ytcB	-	-	M	-	-	-	NAD-dependent epimerase dehydratase
MDKIOEFL_01659	2.27e-307	ytcA	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MDKIOEFL_01660	6.65e-194	ytdA	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
MDKIOEFL_01661	8.68e-169	yteA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
MDKIOEFL_01662	0.0	menF	5.4.4.2	-	HQ	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
MDKIOEFL_01663	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MDKIOEFL_01664	9.85e-197	menH	4.2.99.20	-	S	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
MDKIOEFL_01665	3.45e-200	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MDKIOEFL_01666	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MDKIOEFL_01667	4.09e-272	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
MDKIOEFL_01668	1.53e-216	troA	-	-	P	ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
MDKIOEFL_01669	1.97e-175	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K11710,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MDKIOEFL_01670	1.44e-293	mntC	-	-	P	ko:K11705,ko:K11708,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MDKIOEFL_01671	8.09e-176	mntD	-	-	P	ko:K11709,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
MDKIOEFL_01672	2.43e-34	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1540)
MDKIOEFL_01673	9.47e-238	ythB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG1294 Cytochrome bd-type quinol oxidase, subunit 2
MDKIOEFL_01674	1.03e-315	ythA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
MDKIOEFL_01675	5.02e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
MDKIOEFL_01676	3.65e-133	ytiB	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
MDKIOEFL_01677	8.36e-113	luxS	4.4.1.21	-	T	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MDKIOEFL_01678	4.78e-95	ytkA	-	-	S	-	-	-	YtkA-like
MDKIOEFL_01680	1.8e-99	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
MDKIOEFL_01681	3.2e-81	ytkC	-	-	S	-	-	-	Bacteriophage holin family
MDKIOEFL_01682	1.82e-112	ytkD	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
MDKIOEFL_01683	1.32e-183	ytlD	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MDKIOEFL_01684	6.12e-184	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MDKIOEFL_01685	1.87e-240	ytlA	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
MDKIOEFL_01686	3.86e-190	ytmA	-	-	E	-	-	-	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
MDKIOEFL_01687	2.85e-52	ytmB	-	-	S	-	-	-	Protein of unknown function (DUF2584)
MDKIOEFL_01688	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MDKIOEFL_01689	2.26e-286	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MDKIOEFL_01690	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
MDKIOEFL_01691	0.0	ytnA	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
MDKIOEFL_01692	3.4e-87	ytoA	-	-	S	-	-	-	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MDKIOEFL_01693	4.7e-192	ytpA	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Alpha beta hydrolase
MDKIOEFL_01694	4.81e-276	ytpB	4.2.3.130	-	S	ko:K16188	-	ko00000,ko01000	Tetraprenyl-beta-curcumene synthase
MDKIOEFL_01695	1.17e-133	ytqB	-	-	J	-	-	-	Putative rRNA methylase
MDKIOEFL_01696	2.35e-244	ytqA	-	-	S	ko:K07139	-	ko00000	Fe-S oxidoreductase
MDKIOEFL_01697	1.27e-55	ytzC	-	-	S	-	-	-	Protein of unknown function (DUF2524)
MDKIOEFL_01699	2.68e-87	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	GntR family transcriptional regulator
MDKIOEFL_01700	5.96e-207	ytrB	-	-	P	ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MDKIOEFL_01701	4.18e-216	-	-	-	P	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
MDKIOEFL_01702	2.26e-191	-	-	-	-	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	-
MDKIOEFL_01703	5.88e-163	ytrE	-	-	V	ko:K16920	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MDKIOEFL_01704	1.39e-296	ytrF	-	-	V	ko:K02004,ko:K16918	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
MDKIOEFL_01705	9.07e-167	graR	-	-	T	ko:K11630,ko:K19078	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01504,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MDKIOEFL_01706	1.02e-235	bceS	2.7.13.3	-	T	ko:K11629,ko:K19077	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	His Kinase A (phosphoacceptor) domain
MDKIOEFL_01707	3.83e-179	bceA	-	-	V	ko:K02003,ko:K11631,ko:K19079	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter, ATP-binding protein
MDKIOEFL_01708	0.0	bceB	-	-	V	ko:K11632,ko:K19080	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter (permease)
MDKIOEFL_01709	2.16e-75	yttA	-	-	S	-	-	-	Pfam Transposase IS66
MDKIOEFL_01710	3.47e-268	yttB	-	-	EGP	-	-	-	Major facilitator superfamily
MDKIOEFL_01711	2.21e-182	pfyP	-	-	T	-	-	-	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
MDKIOEFL_01712	3.63e-72	ytvB	-	-	S	-	-	-	Protein of unknown function (DUF4257)
MDKIOEFL_01713	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
MDKIOEFL_01714	4.98e-68	ytwF	-	-	P	-	-	-	Sulfurtransferase
MDKIOEFL_01715	0.0	melA	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
MDKIOEFL_01716	7.65e-186	amyC	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
MDKIOEFL_01717	1.66e-214	amyD	-	-	P	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MDKIOEFL_01718	7.08e-310	msmE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MDKIOEFL_01719	1.07e-242	msmR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
MDKIOEFL_01720	1.13e-219	-	-	-	S	-	-	-	Acetyl xylan esterase (AXE1)
MDKIOEFL_01721	4.34e-177	bioW	6.2.1.14	-	H	ko:K01906	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
MDKIOEFL_01722	0.0	bioA	2.6.1.105, 2.6.1.62	-	H	ko:K00833,ko:K19563	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
MDKIOEFL_01723	1.23e-273	bioF	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MDKIOEFL_01724	2.11e-156	bioD	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MDKIOEFL_01725	1.25e-241	bioB	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MDKIOEFL_01726	4.69e-281	bioI	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
MDKIOEFL_01727	2.21e-178	ytbQ	1.1.1.203, 1.1.1.388	-	GM	ko:K18981,ko:K19243	ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	NAD dependent epimerase/dehydratase family
MDKIOEFL_01728	2.52e-192	ytcP	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
MDKIOEFL_01729	0.0	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
MDKIOEFL_01730	0.0	ytdP	-	-	K	-	-	-	Transcriptional regulator
MDKIOEFL_01731	1.31e-220	lplB13	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4209 ABC-type polysaccharide transport system, permease component
MDKIOEFL_01732	1.96e-277	yteR	3.2.1.172	GH105	G	ko:K15532	-	ko00000,ko01000	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
MDKIOEFL_01733	2.27e-92	yteS	-	-	G	-	-	-	transport
MDKIOEFL_01734	6.02e-315	yteT	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
MDKIOEFL_01735	3.81e-150	yteU	-	-	S	-	-	-	Integral membrane protein
MDKIOEFL_01736	2.14e-36	yteV	-	-	S	-	-	-	Sporulation protein Cse60
MDKIOEFL_01737	0.0	opuD	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
MDKIOEFL_01738	1.41e-293	ytfP	-	-	S	ko:K07007	-	ko00000	HI0933-like protein
MDKIOEFL_01739	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MDKIOEFL_01740	2.13e-169	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MDKIOEFL_01741	4.46e-46	ytzE	-	-	K	-	-	-	COG1349 Transcriptional regulators of sugar metabolism
MDKIOEFL_01742	5.66e-168	ythP	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
MDKIOEFL_01743	1.17e-253	ythQ	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Bacterial ABC transporter protein EcsB
MDKIOEFL_01744	1.73e-288	pbuO	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MDKIOEFL_01745	0.0	ytjP	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Dipeptidase
MDKIOEFL_01746	3e-221	ytkP	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
MDKIOEFL_01747	2.04e-128	ytlP	3.1.4.58	-	J	ko:K01975	-	ko00000,ko01000,ko03016	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MDKIOEFL_01748	2e-211	ytlQ	-	-	-	-	-	-	-
MDKIOEFL_01749	2.22e-231	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
MDKIOEFL_01750	0.0	amyX	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
MDKIOEFL_01751	3.02e-192	ytmP	-	-	M	-	-	-	Phosphotransferase
MDKIOEFL_01752	9.51e-61	ytzH	-	-	S	-	-	-	YtzH-like protein
MDKIOEFL_01753	2.16e-156	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MDKIOEFL_01754	1.3e-191	ytnP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
MDKIOEFL_01755	0.0	malS	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
MDKIOEFL_01756	1.17e-67	ytzB	-	-	S	-	-	-	small secreted protein
MDKIOEFL_01757	3.71e-261	pepA	3.4.11.7	-	G	ko:K01261,ko:K01269	-	ko00000,ko01000,ko01002	COG1363 Cellulase M and related proteins
MDKIOEFL_01758	7.02e-103	ytoQ	-	-	S	-	-	-	Nucleoside 2-deoxyribosyltransferase YtoQ
MDKIOEFL_01759	3.17e-75	ytpP	-	-	CO	-	-	-	Thioredoxin
MDKIOEFL_01760	1.02e-191	ytpQ	-	-	S	-	-	-	Belongs to the UPF0354 family
MDKIOEFL_01761	1.78e-140	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MDKIOEFL_01762	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
MDKIOEFL_01763	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
MDKIOEFL_01764	2.38e-63	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MDKIOEFL_01765	3.17e-30	ytxH	-	-	S	-	-	-	COG4980 Gas vesicle protein
MDKIOEFL_01766	1.51e-69	ytxJ	-	-	O	-	-	-	Protein of unknown function (DUF2847)
MDKIOEFL_01767	7.64e-250	aroA	2.5.1.54, 5.4.99.5	-	E	ko:K03856,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
MDKIOEFL_01768	1.7e-234	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
MDKIOEFL_01769	6.84e-187	motP	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
MDKIOEFL_01770	1.6e-161	ytxE	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
MDKIOEFL_01771	1.49e-289	acuC	-	-	BQ	ko:K04768	-	ko00000	histone deacetylase
MDKIOEFL_01772	6.16e-152	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
MDKIOEFL_01773	2.43e-156	acuA	-	-	K	ko:K04766	-	ko00000,ko01000	Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
MDKIOEFL_01774	0.0	acsA	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MDKIOEFL_01775	5.31e-303	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MDKIOEFL_01777	2.01e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MDKIOEFL_01778	0.0	ytrP	-	-	T	-	-	-	COG2199 FOG GGDEF domain
MDKIOEFL_01779	1.13e-113	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
MDKIOEFL_01780	1.2e-141	yttP	-	-	K	-	-	-	Transcriptional regulator
MDKIOEFL_01781	7.52e-198	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	COG1387 Histidinol phosphatase and related hydrolases of the PHP family
MDKIOEFL_01782	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MDKIOEFL_01783	2.36e-304	braB	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
MDKIOEFL_01784	4.55e-265	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
MDKIOEFL_01785	2.55e-288	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MDKIOEFL_01786	2.12e-40	-	-	-	S	ko:K06418,ko:K06419,ko:K06420	-	ko00000	spore protein
MDKIOEFL_01787	0.0	ytcI	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MDKIOEFL_01788	0.0	ytcJ	-	-	S	-	-	-	amidohydrolase
MDKIOEFL_01789	1.69e-189	nadK2	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MDKIOEFL_01790	2.39e-230	sppA	-	-	OU	ko:K04773	-	ko00000,ko01000,ko01002	signal peptide peptidase SppA
MDKIOEFL_01791	2.36e-111	yteJ	-	-	S	-	-	-	RDD family
MDKIOEFL_01792	8.34e-149	ytfI	-	-	S	-	-	-	Protein of unknown function (DUF2953)
MDKIOEFL_01793	1.06e-94	ytfJ	-	-	S	-	-	-	Sporulation protein YtfJ
MDKIOEFL_01794	1.93e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MDKIOEFL_01795	1.26e-222	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
MDKIOEFL_01796	4.69e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MDKIOEFL_01797	9.12e-112	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
MDKIOEFL_01798	1.06e-297	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
MDKIOEFL_01799	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
MDKIOEFL_01801	1.98e-182	ytkK	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MDKIOEFL_01802	1.91e-166	ytkL	-	-	S	-	-	-	Belongs to the UPF0173 family
MDKIOEFL_01803	1.13e-308	ytoI	-	-	K	-	-	-	transcriptional regulator containing CBS domains
MDKIOEFL_01804	2.15e-63	ytpI	-	-	S	-	-	-	YtpI-like protein
MDKIOEFL_01805	1.24e-230	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	COG0618 Exopolyphosphatase-related proteins
MDKIOEFL_01806	1.15e-39	-	-	-	-	-	-	-	-
MDKIOEFL_01807	5.12e-112	ytrI	-	-	-	-	-	-	-
MDKIOEFL_01808	2.45e-75	ytrH	-	-	S	-	-	-	Sporulation protein YtrH
MDKIOEFL_01809	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
MDKIOEFL_01810	2.01e-285	ytsJ	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
MDKIOEFL_01811	1.25e-207	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MDKIOEFL_01812	9.82e-234	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
MDKIOEFL_01813	4.65e-229	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MDKIOEFL_01814	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
MDKIOEFL_01815	9.07e-80	fxsA	-	-	S	ko:K07113	-	ko00000	COG3030 Protein affecting phage T7 exclusion by the F plasmid
MDKIOEFL_01816	7.83e-245	ytvI	-	-	S	-	-	-	sporulation integral membrane protein YtvI
MDKIOEFL_01817	9.38e-95	ytwI	-	-	S	-	-	-	membrane
MDKIOEFL_01818	3.34e-267	citZ	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
MDKIOEFL_01819	2.28e-309	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	isocitrate
MDKIOEFL_01820	1.04e-217	mdh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible oxidation of malate to oxaloacetate
MDKIOEFL_01821	1.62e-169	phoP	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MDKIOEFL_01822	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase
MDKIOEFL_01823	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MDKIOEFL_01824	4.73e-201	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MDKIOEFL_01825	3.97e-137	ytaF	-	-	P	-	-	-	Probably functions as a manganese efflux pump
MDKIOEFL_01826	8.07e-126	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MDKIOEFL_01827	3.07e-203	ytbE	-	-	S	-	-	-	reductase
MDKIOEFL_01828	3.92e-255	ytbD	-	-	EGP	ko:K19577	-	ko00000,ko02000	-transporter
MDKIOEFL_01829	9.85e-88	ytcD	-	-	K	-	-	-	Transcriptional regulator
MDKIOEFL_01830	1.73e-246	gapB	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MDKIOEFL_01831	2.42e-88	speH	4.1.1.50	-	E	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MDKIOEFL_01832	2.42e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MDKIOEFL_01833	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	Membrane attachment protein
MDKIOEFL_01834	1e-219	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
MDKIOEFL_01835	1.33e-141	ytxB	-	-	S	-	-	-	SNARE associated Golgi protein
MDKIOEFL_01836	3.46e-205	ytxC	-	-	S	-	-	-	YtxC-like family
MDKIOEFL_01838	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MDKIOEFL_01839	1.98e-189	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
MDKIOEFL_01840	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MDKIOEFL_01841	1.96e-166	lytT	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
MDKIOEFL_01842	8.47e-85	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
MDKIOEFL_01843	5.34e-150	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
MDKIOEFL_01845	1.81e-111	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MDKIOEFL_01846	3.93e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
MDKIOEFL_01847	3.26e-76	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MDKIOEFL_01848	1.27e-59	ysdA	-	-	S	-	-	-	Membrane
MDKIOEFL_01849	2.29e-88	ysdB	-	-	S	-	-	-	Sigma-w pathway protein YsdB
MDKIOEFL_01850	6.18e-262	ysdC	-	-	G	-	-	-	COG1363 Cellulase M and related proteins
MDKIOEFL_01851	9.92e-242	-	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
MDKIOEFL_01852	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
MDKIOEFL_01853	0.0	araB	2.7.1.16	-	C	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Belongs to the ribulokinase family
MDKIOEFL_01854	1.7e-170	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
MDKIOEFL_01855	1e-185	araL	-	-	G	ko:K02101	-	ko00000	Haloacid dehalogenase-like hydrolase
MDKIOEFL_01856	5.51e-284	araM	1.1.1.261	-	I	ko:K00096	ko00564,map00564	ko00000,ko00001,ko01000	Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
MDKIOEFL_01857	0.0	araN	-	-	G	ko:K17234	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
MDKIOEFL_01858	1.94e-218	araP	-	-	G	ko:K17235	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
MDKIOEFL_01859	6.34e-192	araQ	-	-	G	ko:K17236	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport system permease
MDKIOEFL_01860	0.0	abfA	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	alpha-L-arabinofuranosidase activity
MDKIOEFL_01861	0.0	cstA	-	-	T	ko:K06200	-	ko00000	Carbon starvation protein
MDKIOEFL_01862	2.07e-69	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase-like domain
MDKIOEFL_01863	0.0	glcF	-	-	C	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	Glycolate oxidase
MDKIOEFL_01864	0.0	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Glycolate oxidase subunit
MDKIOEFL_01865	1.45e-259	cdaR_1	-	-	KT	ko:K02647	-	ko00000,ko03000	regulator
MDKIOEFL_01866	4.37e-43	sspI	-	-	S	ko:K06426	-	ko00000	Belongs to the SspI family
MDKIOEFL_01867	3.13e-171	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MDKIOEFL_01868	1.81e-250	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MDKIOEFL_01869	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MDKIOEFL_01870	8.48e-215	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MDKIOEFL_01871	1.04e-54	zapA	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MDKIOEFL_01872	3.12e-111	yshB	-	-	S	-	-	-	membrane protein, required for colicin V production
MDKIOEFL_01873	0.0	polX	-	-	L	ko:K02347	-	ko00000,ko03400	COG1796 DNA polymerase IV (family X)
MDKIOEFL_01874	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MDKIOEFL_01875	3.76e-89	yshE	-	-	S	ko:K08989	-	ko00000	membrane
MDKIOEFL_01876	0.0	lcfA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MDKIOEFL_01877	5.74e-129	fadR	-	-	K	ko:K13770	-	ko00000,ko03000	Transcriptional regulator
MDKIOEFL_01878	6.3e-176	fadB	4.2.1.17	-	I	ko:K13767	ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the enoyl-CoA hydratase isomerase family
MDKIOEFL_01879	3.01e-178	etfB	-	-	C	ko:K03521	-	ko00000	Electron transfer flavoprotein
MDKIOEFL_01880	8.29e-226	etfA	-	-	C	ko:K03522	-	ko00000,ko04147	Electron transfer flavoprotein
MDKIOEFL_01881	0.0	xsa	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
MDKIOEFL_01882	1.12e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
MDKIOEFL_01883	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MDKIOEFL_01884	3.96e-275	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
MDKIOEFL_01885	8.53e-104	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
MDKIOEFL_01886	1.35e-140	sdhC	-	-	C	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	succinate dehydrogenase
MDKIOEFL_01887	0.0	sdhA	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
MDKIOEFL_01888	2.33e-189	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
MDKIOEFL_01889	3.1e-101	ysmA	-	-	S	ko:K07107	-	ko00000,ko01000	thioesterase
MDKIOEFL_01890	1.81e-41	gerE	-	-	K	ko:K01994	-	ko00000,ko03000	Transcriptional regulator
MDKIOEFL_01891	1.6e-98	ysmB	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MDKIOEFL_01892	4.49e-194	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
MDKIOEFL_01893	5.65e-256	gerM	-	-	S	ko:K06298	-	ko00000	COG5401 Spore germination protein
MDKIOEFL_01894	3.53e-171	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MDKIOEFL_01895	3.05e-132	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MDKIOEFL_01896	2.34e-118	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
MDKIOEFL_01898	2.76e-182	ysnF	-	-	S	-	-	-	protein conserved in bacteria
MDKIOEFL_01899	1.32e-148	-	-	-	N	-	-	-	domain, Protein
MDKIOEFL_01900	4.03e-99	ysnE	-	-	K	ko:K03829	-	ko00000,ko01000	acetyltransferase
MDKIOEFL_01902	0.0	ilvB	2.2.1.6	-	E	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
MDKIOEFL_01903	5.05e-110	ilvN	2.2.1.6	-	E	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
MDKIOEFL_01904	7.88e-244	ilvC	1.1.1.86	-	EH	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MDKIOEFL_01905	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MDKIOEFL_01906	2.13e-255	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MDKIOEFL_01907	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MDKIOEFL_01908	4.4e-149	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MDKIOEFL_01909	7.51e-238	ysoA	-	-	H	-	-	-	Tetratricopeptide repeat
MDKIOEFL_01910	2.54e-286	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MDKIOEFL_01911	1.15e-296	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MDKIOEFL_01912	0.0	lonB	3.4.21.53	-	LO	ko:K04076	-	ko00000,ko01000,ko01002	Belongs to the peptidase S16 family
MDKIOEFL_01913	0.0	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MDKIOEFL_01914	7.6e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
MDKIOEFL_01915	4.77e-116	ysxD	-	-	-	-	-	-	-
MDKIOEFL_01916	1.92e-315	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MDKIOEFL_01917	6.56e-187	hemX	-	-	O	ko:K02497	-	ko00000	cytochrome C
MDKIOEFL_01918	8.91e-220	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
MDKIOEFL_01919	1.01e-183	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
MDKIOEFL_01920	3.7e-233	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the ALAD family
MDKIOEFL_01921	8.3e-311	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
MDKIOEFL_01922	5.71e-311	spoVID	-	-	M	ko:K06417	-	ko00000	stage VI sporulation protein D
MDKIOEFL_01923	1.61e-250	ysxE	-	-	S	-	-	-	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MDKIOEFL_01924	1.53e-35	-	-	-	-	-	-	-	-
MDKIOEFL_01925	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MDKIOEFL_01926	1.83e-314	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
MDKIOEFL_01927	6.04e-107	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
MDKIOEFL_01928	1.01e-209	spoIIB	-	-	S	ko:K06380	-	ko00000	Sporulation related domain
MDKIOEFL_01929	1e-131	maf	-	-	D	ko:K06287	-	ko00000	septum formation protein Maf
MDKIOEFL_01930	8.35e-163	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
MDKIOEFL_01931	5.26e-235	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein MreB
MDKIOEFL_01932	7.78e-202	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
MDKIOEFL_01933	2.5e-110	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	shape-determining protein
MDKIOEFL_01934	4.3e-158	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MDKIOEFL_01935	2.91e-186	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
MDKIOEFL_01936	5.24e-187	spoIVFA	-	-	M	ko:K06401	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
MDKIOEFL_01937	3.74e-208	spoIVFB	-	-	S	ko:K06402	-	ko00000,ko01000,ko01002	Stage IV sporulation protein
MDKIOEFL_01938	6.34e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
MDKIOEFL_01939	2.66e-74	ysxB	-	-	J	ko:K07584	-	ko00000	ribosomal protein
MDKIOEFL_01940	2.7e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
MDKIOEFL_01941	4.25e-139	spo0B	-	-	T	ko:K06375	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01000	Sporulation initiation phospho-transferase B, C-terminal
MDKIOEFL_01942	2.27e-307	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MDKIOEFL_01943	4.75e-96	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
MDKIOEFL_01944	1.18e-207	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
MDKIOEFL_01945	1.44e-122	yrxA	-	-	S	ko:K07105	-	ko00000	small molecule binding protein (contains 3H domain)
MDKIOEFL_01946	9.57e-277	nifS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
MDKIOEFL_01947	0.0	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
MDKIOEFL_01948	5.92e-201	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NadC ModD family
MDKIOEFL_01949	4.41e-270	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MDKIOEFL_01950	2.43e-217	safA	-	-	M	ko:K06370	-	ko00000	spore coat assembly protein SafA
MDKIOEFL_01951	2.55e-70	-	-	-	S	ko:K06345	-	ko00000	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MDKIOEFL_01952	3.51e-164	yebC	-	-	K	-	-	-	transcriptional regulatory protein
MDKIOEFL_01953	0.0	yrbD	-	-	E	ko:K03310	-	ko00000	Sodium alanine symporter
MDKIOEFL_01954	6.26e-68	-	-	-	S	-	-	-	Family of unknown function (DUF5412)
MDKIOEFL_01956	7.77e-151	yrzF	-	-	T	-	-	-	serine threonine protein kinase
MDKIOEFL_01957	2.77e-248	idhA	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
MDKIOEFL_01958	0.0	csbX	-	-	EGP	-	-	-	the major facilitator superfamily
MDKIOEFL_01959	6.46e-121	bofC	-	-	S	ko:K06318	-	ko00000	BofC C-terminal domain
MDKIOEFL_01960	2.84e-137	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MDKIOEFL_01961	9.14e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MDKIOEFL_01962	2.91e-30	yrzS	-	-	S	-	-	-	Protein of unknown function (DUF2905)
MDKIOEFL_01963	7.04e-247	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MDKIOEFL_01964	4.74e-292	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MDKIOEFL_01965	1.29e-52	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit YajC
MDKIOEFL_01966	1.2e-95	yrzE	-	-	S	-	-	-	Protein of unknown function (DUF3792)
MDKIOEFL_01967	5.83e-143	yrbG	-	-	S	-	-	-	membrane
MDKIOEFL_01968	0.0	spoVB	-	-	S	ko:K06409	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MDKIOEFL_01969	5.53e-65	yrzD	-	-	S	-	-	-	Post-transcriptional regulator
MDKIOEFL_01970	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MDKIOEFL_01971	2.97e-110	trkA1	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
MDKIOEFL_01972	1.07e-64	yrvD	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
MDKIOEFL_01973	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
MDKIOEFL_01974	2.53e-118	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MDKIOEFL_01975	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MDKIOEFL_01976	1.36e-90	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MDKIOEFL_01977	0.0	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	COG3103 SH3 domain protein
MDKIOEFL_01979	1.22e-309	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
MDKIOEFL_01980	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MDKIOEFL_01981	6.57e-176	yrvM	-	-	H	ko:K22132	-	ko00000,ko03016	COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
MDKIOEFL_01982	2.44e-303	rarA	-	-	L	ko:K07478	-	ko00000	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
MDKIOEFL_01983	8.12e-93	cymR	-	-	K	ko:K17472	-	ko00000,ko03000	Transcriptional regulator
MDKIOEFL_01984	2.98e-269	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
MDKIOEFL_01985	5.64e-279	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MDKIOEFL_01986	1.02e-38	yrrB	-	-	S	-	-	-	COG0457 FOG TPR repeat
MDKIOEFL_01987	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MDKIOEFL_01988	1.44e-107	yrrD	-	-	S	-	-	-	protein conserved in bacteria
MDKIOEFL_01989	8.4e-42	yrzR	-	-	-	-	-	-	-
MDKIOEFL_01990	5.38e-12	-	-	-	S	-	-	-	Protein of unknown function (DUF3918)
MDKIOEFL_01991	9.26e-140	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MDKIOEFL_01992	3.24e-139	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MDKIOEFL_01993	1.01e-184	glnH	-	-	ET	ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
MDKIOEFL_01994	2.21e-168	glnQ	-	-	E	ko:K09972,ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
MDKIOEFL_01995	1.25e-241	yrrI	-	-	S	-	-	-	AI-2E family transporter
MDKIOEFL_01996	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MDKIOEFL_01997	2.22e-55	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
MDKIOEFL_01998	5.49e-93	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MDKIOEFL_01999	2.94e-60	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
MDKIOEFL_02000	4.17e-241	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MDKIOEFL_02001	1.98e-154	yrrM	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-methyltransferase
MDKIOEFL_02002	3.64e-221	yrrN	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
MDKIOEFL_02003	4.62e-313	yrrO	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	COG0826 Collagenase and related proteases
MDKIOEFL_02004	4.51e-148	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
MDKIOEFL_02005	1.14e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MDKIOEFL_02006	0.0	pbpI	-	-	M	ko:K21468	-	ko00000,ko01011	Penicillin-binding Protein
MDKIOEFL_02007	8.2e-102	yrrS	-	-	S	-	-	-	Protein of unknown function (DUF1510)
MDKIOEFL_02008	4.94e-36	yrzA	-	-	S	-	-	-	Protein of unknown function (DUF2536)
MDKIOEFL_02009	3.44e-153	yrrT	-	-	Q	ko:K17462	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Could be a S-adenosyl-L-methionine-dependent methyltransferase
MDKIOEFL_02010	5.64e-161	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MDKIOEFL_02011	3.91e-215	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Cysteine synthase
MDKIOEFL_02012	4.95e-268	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
MDKIOEFL_02013	6.93e-49	yrhC	-	-	S	-	-	-	YrhC-like protein
MDKIOEFL_02014	6.05e-103	yrhD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
MDKIOEFL_02015	0.0	yjgC	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase (NAD+) activity
MDKIOEFL_02016	4.41e-80	yrhF	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
MDKIOEFL_02017	1.38e-183	yrhG	-	-	P	ko:K21993	-	ko00000,ko02000	Formate nitrite
MDKIOEFL_02019	9.39e-08	-	-	-	S	-	-	-	Probable sporulation protein (Bac_small_yrzI)
MDKIOEFL_02020	6.1e-124	yrhH	-	-	Q	-	-	-	methyltransferase
MDKIOEFL_02021	2.26e-135	-	-	-	K	ko:K22106	-	ko00000,ko03000	Tetracycline repressor, C-terminal all-alpha domain
MDKIOEFL_02022	0.0	yrhJ	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
MDKIOEFL_02023	6.32e-59	yrhK	-	-	S	-	-	-	YrhK-like protein
MDKIOEFL_02024	0.0	oatA	-	-	I	-	-	-	Acyltransferase family
MDKIOEFL_02025	1.43e-190	rsiV	-	-	S	-	-	-	Protein of unknown function (DUF3298)
MDKIOEFL_02026	9.97e-114	sigV	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MDKIOEFL_02027	1.19e-193	yrhO	-	-	K	-	-	-	Archaeal transcriptional regulator TrmB
MDKIOEFL_02028	3.26e-136	yrhP	-	-	E	-	-	-	LysE type translocator
MDKIOEFL_02029	0.0	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
MDKIOEFL_02030	0.0	levR	-	-	K	-	-	-	PTS system fructose IIA component
MDKIOEFL_02031	2.66e-97	levD	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11194	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
MDKIOEFL_02032	7.63e-107	ptnA	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11195	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system mannose fructose sorbose family
MDKIOEFL_02033	2.79e-166	levF	-	-	G	ko:K02746,ko:K02795,ko:K11196	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
MDKIOEFL_02034	1.39e-192	levG	-	-	G	ko:K02771,ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
MDKIOEFL_02035	0.0	sacC	3.2.1.80	-	G	ko:K03332	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
MDKIOEFL_02036	1.58e-116	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
MDKIOEFL_02037	1.61e-251	adhA	-	-	C	ko:K13979	-	ko00000,ko01000	alcohol dehydrogenase
MDKIOEFL_02038	1.86e-24	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	peroxiredoxin activity
MDKIOEFL_02039	1.83e-67	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
MDKIOEFL_02040	7.23e-66	yraD	-	-	M	ko:K06439	-	ko00000	Spore coat protein
MDKIOEFL_02041	1.23e-35	yraE	-	-	-	ko:K06440	-	ko00000	-
MDKIOEFL_02042	2.8e-278	adhB	1.1.1.1, 1.1.1.284, 1.2.1.46	-	E	ko:K00121,ko:K00148	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MDKIOEFL_02043	9.61e-84	yraF	-	-	M	-	-	-	Spore coat protein
MDKIOEFL_02044	4.19e-50	yraG	-	-	-	ko:K06440	-	ko00000	-
MDKIOEFL_02045	6.62e-87	-	-	-	E	-	-	-	Glyoxalase-like domain
MDKIOEFL_02046	2.92e-81	-	-	-	T	-	-	-	sh3 domain protein
MDKIOEFL_02047	6.61e-80	-	-	-	T	-	-	-	sh3 domain protein
MDKIOEFL_02048	5.9e-192	-	-	-	S	-	-	-	Alpha beta hydrolase
MDKIOEFL_02049	5.07e-56	yraL	-	-	S	-	-	-	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MDKIOEFL_02050	2.57e-192	csn	3.2.1.132	-	M	ko:K01233	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
MDKIOEFL_02051	1.15e-260	yraM	-	-	S	-	-	-	PrpF protein
MDKIOEFL_02052	7e-209	yraN	-	-	K	-	-	-	Transcriptional regulator
MDKIOEFL_02053	2.06e-283	yraO	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
MDKIOEFL_02054	4.03e-238	yrpG	-	-	C	-	-	-	Aldo/keto reductase family
MDKIOEFL_02055	2.5e-121	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MDKIOEFL_02056	4.22e-164	zinT	-	-	S	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
MDKIOEFL_02057	1.51e-85	napB	-	-	K	-	-	-	MarR family transcriptional regulator
MDKIOEFL_02058	7.88e-281	yfjF	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily
MDKIOEFL_02060	2.22e-175	-	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	COG3959 Transketolase, N-terminal subunit
MDKIOEFL_02061	6.83e-191	-	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transketolase, pyrimidine binding domain
MDKIOEFL_02062	1.7e-145	-	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MDKIOEFL_02063	2.76e-266	-	-	-	P	-	-	-	Major Facilitator Superfamily
MDKIOEFL_02065	2.34e-128	-	-	-	K	ko:K05799	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
MDKIOEFL_02066	2.39e-162	yrpD	-	-	S	-	-	-	Domain of unknown function, YrpD
MDKIOEFL_02067	8.38e-189	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
MDKIOEFL_02068	1.04e-246	npd	1.13.12.16	-	S	ko:K00459	ko00910,map00910	ko00000,ko00001,ko01000	COG2070 Dioxygenases related to 2-nitropropane dioxygenase
MDKIOEFL_02069	1.48e-212	aadK	-	-	G	ko:K05593	-	ko00000,ko01000,ko01504	Streptomycin adenylyltransferase
MDKIOEFL_02070	1.42e-118	yrdA	-	-	S	-	-	-	DinB family
MDKIOEFL_02071	1.48e-71	-	-	-	S	-	-	-	Protein of unknown function (DUF2568)
MDKIOEFL_02072	6.06e-130	yrdC	-	-	Q	-	-	-	Isochorismatase family
MDKIOEFL_02073	7.64e-290	cypA	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
MDKIOEFL_02074	7.91e-55	yrdF	-	-	K	ko:K03623	-	ko00000	ribonuclease inhibitor
MDKIOEFL_02075	4.82e-103	bkdR	-	-	K	-	-	-	helix_turn_helix ASNC type
MDKIOEFL_02076	3.8e-175	azlC	-	-	E	-	-	-	AzlC protein
MDKIOEFL_02077	1.97e-66	azlD	-	-	E	-	-	-	Branched-chain amino acid transport protein (AzlD)
MDKIOEFL_02078	2.88e-291	brnQ	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
MDKIOEFL_02080	6e-213	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	COG1230 Co Zn Cd efflux system component
MDKIOEFL_02081	1.01e-252	trkA	-	-	P	ko:K07222	-	ko00000	Oxidoreductase
MDKIOEFL_02082	1.64e-202	-	-	-	K	-	-	-	Transcriptional regulator
MDKIOEFL_02083	4.91e-216	yrdR	-	-	EG	-	-	-	EamA-like transporter family
MDKIOEFL_02084	7.04e-23	-	-	-	S	-	-	-	YrzO-like protein
MDKIOEFL_02085	2.4e-296	yrkA	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
MDKIOEFL_02086	6.19e-108	bltD	2.3.1.57	-	K	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	FR47-like protein
MDKIOEFL_02087	6.23e-268	blt	-	-	EGP	ko:K08153,ko:K19578	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
MDKIOEFL_02088	3.56e-194	bltR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MDKIOEFL_02089	7.4e-137	yrkC	-	-	G	-	-	-	Cupin domain
MDKIOEFL_02090	2.7e-27	-	-	-	-	-	-	-	-
MDKIOEFL_02091	4.38e-52	yrkD	-	-	S	-	-	-	protein conserved in bacteria
MDKIOEFL_02092	6.83e-109	yrkE	-	-	O	-	-	-	DsrE/DsrF/DrsH-like family
MDKIOEFL_02093	3.95e-127	yrkF	-	-	OP	-	-	-	Belongs to the sulfur carrier protein TusA family
MDKIOEFL_02094	0.000112	perX	-	-	S	-	-	-	DsrE/DsrF-like family
MDKIOEFL_02095	1.78e-264	yrkH	-	-	P	-	-	-	Rhodanese Homology Domain
MDKIOEFL_02096	6.46e-49	yrkI	-	-	O	-	-	-	Belongs to the sulfur carrier protein TusA family
MDKIOEFL_02097	3.24e-159	yrkJ	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MDKIOEFL_02098	3.13e-104	-	-	-	S	-	-	-	Protein of unknown function with HXXEE motif
MDKIOEFL_02099	5.71e-126	yrkL	-	-	S	ko:K11748	-	ko00000,ko02000	Flavodoxin-like fold
MDKIOEFL_02100	7.39e-132	yrkN	-	-	K	-	-	-	Acetyltransferase (GNAT) family
MDKIOEFL_02101	1.52e-282	yrkO	-	-	P	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
MDKIOEFL_02102	7.15e-164	yrkP	-	-	T	ko:K02483	-	ko00000,ko02022	Transcriptional regulator
MDKIOEFL_02103	4.23e-305	yrkQ	-	-	T	-	-	-	Histidine kinase
MDKIOEFL_02104	2.15e-90	psiE	-	-	S	ko:K13256	-	ko00000	Protein PsiE homolog
MDKIOEFL_02105	4.46e-79	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MDKIOEFL_02106	1.85e-121	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
MDKIOEFL_02107	3.25e-55	-	-	-	S	-	-	-	Putative small multi-drug export protein
MDKIOEFL_02108	6.53e-85	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MDKIOEFL_02110	1.88e-42	-	-	-	K	-	-	-	sequence-specific DNA binding
MDKIOEFL_02111	1.02e-24	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
MDKIOEFL_02113	4.26e-133	-	-	-	-	-	-	-	-
MDKIOEFL_02117	4.58e-220	yqaJ	-	-	L	-	-	-	YqaJ-like viral recombinase domain
MDKIOEFL_02118	4.62e-191	recT	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
MDKIOEFL_02119	8.41e-153	yqaL	-	-	L	-	-	-	DnaD domain protein
MDKIOEFL_02120	2.61e-209	yqaM	-	-	L	-	-	-	IstB-like ATP binding protein
MDKIOEFL_02122	1.89e-95	rusA	-	-	L	-	-	-	Endodeoxyribonuclease RusA
MDKIOEFL_02123	1.02e-42	yqaO	-	-	S	-	-	-	Phage-like element PBSX protein XtrA
MDKIOEFL_02125	7.61e-60	-	-	-	M	-	-	-	ArpU family transcriptional regulator
MDKIOEFL_02126	3.16e-91	-	-	-	LU	-	-	-	DNA recombination-mediator protein A
MDKIOEFL_02129	3.62e-139	yqaS	-	-	L	-	-	-	DNA packaging
MDKIOEFL_02130	1.62e-313	yqaT	-	-	S	ko:K06909	-	ko00000	phage terminase, large subunit
MDKIOEFL_02131	0.0	yqbA	-	-	S	-	-	-	portal protein
MDKIOEFL_02132	1.15e-190	-	-	-	S	-	-	-	Phage Mu protein F like protein
MDKIOEFL_02133	6.28e-91	-	-	-	S	-	-	-	Phage Mu protein F like protein
MDKIOEFL_02134	1.11e-162	yqbD	-	-	L	-	-	-	Putative phage serine protease XkdF
MDKIOEFL_02135	4.37e-214	xkdG	-	-	S	-	-	-	Phage capsid family
MDKIOEFL_02136	1.55e-62	-	-	-	S	-	-	-	YqbF, hypothetical protein domain
MDKIOEFL_02137	7.09e-88	-	-	-	S	-	-	-	Protein of unknown function (DUF3199)
MDKIOEFL_02138	1.13e-81	yqbH	-	-	S	-	-	-	Domain of unknown function (DUF3599)
MDKIOEFL_02139	2.64e-114	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
MDKIOEFL_02140	1.73e-97	yqbJ	-	-	-	-	-	-	-
MDKIOEFL_02141	8.49e-35	-	-	-	-	-	-	-	-
MDKIOEFL_02142	0.0	xkdK	-	-	S	-	-	-	Phage tail sheath C-terminal domain
MDKIOEFL_02143	4.23e-99	xkdM	-	-	S	-	-	-	Phage tail tube protein
MDKIOEFL_02144	3.71e-87	-	-	-	S	-	-	-	Phage XkdN-like tail assembly chaperone protein, TAC
MDKIOEFL_02145	0.0	xkdO	-	-	L	-	-	-	Transglycosylase SLT domain
MDKIOEFL_02146	4e-155	xkdP	-	-	S	-	-	-	Lysin motif
MDKIOEFL_02147	3.13e-226	xkdQ	-	-	G	-	-	-	NLP P60 protein
MDKIOEFL_02148	4.04e-42	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
MDKIOEFL_02149	8.65e-87	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
MDKIOEFL_02150	7.78e-238	-	-	-	S	-	-	-	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
MDKIOEFL_02151	2.85e-128	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2313)
MDKIOEFL_02152	9.33e-49	-	-	-	-	-	-	-	-
MDKIOEFL_02153	1.01e-274	-	-	-	-	-	-	-	-
MDKIOEFL_02154	4.8e-72	xkdW	-	-	S	-	-	-	XkdW protein
MDKIOEFL_02155	4.17e-27	-	-	-	-	-	-	-	-
MDKIOEFL_02156	1.3e-208	xepA	-	-	-	-	-	-	-
MDKIOEFL_02157	9.76e-88	-	-	-	S	-	-	-	Bacteriophage holin family
MDKIOEFL_02158	2.01e-163	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
MDKIOEFL_02160	0.0	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	nucleic acid phosphodiester bond hydrolysis
MDKIOEFL_02162	3.5e-119	-	-	-	S	-	-	-	Tetratricopeptide repeat
MDKIOEFL_02163	7.7e-138	-	-	-	K	ko:K05799	-	ko00000,ko03000	FCD
MDKIOEFL_02164	8.16e-242	yycB1	-	-	P	ko:K03449	-	ko00000,ko02000	COG2807 Cyanate permease
MDKIOEFL_02166	2.17e-107	-	-	-	E	-	-	-	LysE type translocator
MDKIOEFL_02167	3.84e-184	-	-	-	K	-	-	-	LysR substrate binding domain
MDKIOEFL_02168	1.38e-178	gmT1	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MDKIOEFL_02169	2.85e-224	-	-	-	KT	-	-	-	Transcriptional regulator
MDKIOEFL_02170	1.58e-193	-	5.1.1.4	-	E	ko:K01777	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Proline racemase
MDKIOEFL_02171	1.19e-248	-	-	-	E	-	-	-	Amino acid permease
MDKIOEFL_02172	3.95e-176	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	Ornithine cyclodeaminase/mu-crystallin family
MDKIOEFL_02173	8.45e-196	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MDKIOEFL_02174	8.93e-258	cypA	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
MDKIOEFL_02175	1.62e-82	bltR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MDKIOEFL_02176	4.88e-126	-	-	-	K	-	-	-	QacR-like protein, C-terminal region
MDKIOEFL_02177	1.36e-90	-	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MDKIOEFL_02178	4.78e-105	ybfM	-	-	S	-	-	-	SNARE associated Golgi protein
MDKIOEFL_02179	5.15e-261	-	-	-	EGP	-	-	-	Transmembrane secretion effector
MDKIOEFL_02181	0.0	-	-	-	L	ko:K06400	-	ko00000	Recombinase
MDKIOEFL_02182	1.1e-72	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MDKIOEFL_02183	2.53e-97	nucB	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
MDKIOEFL_02184	6.34e-169	-	-	-	-	-	-	-	-
MDKIOEFL_02185	8.54e-214	yqeC	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconate dehydrogenase
MDKIOEFL_02186	3.81e-134	yqeD	-	-	S	-	-	-	SNARE associated Golgi protein
MDKIOEFL_02187	5.03e-178	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
MDKIOEFL_02188	6.41e-182	yqeF	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MDKIOEFL_02190	2.17e-123	yqeG	-	-	S	ko:K07015	-	ko00000	hydrolase of the HAD superfamily
MDKIOEFL_02191	4.78e-273	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
MDKIOEFL_02192	1.4e-199	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MDKIOEFL_02193	8.95e-61	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein containing KH domain, possibly ribosomal protein
MDKIOEFL_02194	2.47e-141	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MDKIOEFL_02195	3.95e-132	yqeK	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
MDKIOEFL_02196	9.39e-80	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MDKIOEFL_02197	5.67e-178	yqeM	-	-	Q	-	-	-	Methyltransferase
MDKIOEFL_02198	4.46e-188	comER	-	-	E	ko:K02239	-	ko00000,ko00002,ko02044	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MDKIOEFL_02199	1.5e-134	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	COG1555 DNA uptake protein and related DNA-binding proteins
MDKIOEFL_02200	3.25e-137	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
MDKIOEFL_02201	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
MDKIOEFL_02202	2.36e-22	-	-	-	S	-	-	-	YqzM-like protein
MDKIOEFL_02203	2.35e-243	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
MDKIOEFL_02204	4e-49	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
MDKIOEFL_02205	9.8e-258	gpr	3.4.24.78	-	C	ko:K06012	-	ko00000,ko01000,ko01002	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MDKIOEFL_02206	2.73e-283	spoIIP	-	-	M	ko:K06385	-	ko00000	stage II sporulation protein P
MDKIOEFL_02207	1.67e-68	yqxA	-	-	S	-	-	-	Protein of unknown function (DUF3679)
MDKIOEFL_02208	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MDKIOEFL_02209	2.9e-276	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
MDKIOEFL_02210	1.65e-241	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MDKIOEFL_02211	4.36e-116	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MDKIOEFL_02212	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
MDKIOEFL_02213	3.41e-257	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MDKIOEFL_02214	5.63e-226	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Methylates ribosomal protein L11
MDKIOEFL_02215	6.85e-179	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MDKIOEFL_02216	0.0	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	ribosomal protein S12 methylthiotransferase
MDKIOEFL_02217	4.02e-201	yqeW	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
MDKIOEFL_02218	1.03e-26	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
MDKIOEFL_02219	2.25e-90	yqeY	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
MDKIOEFL_02220	7.62e-290	yqeZ	-	-	O	ko:K07403	-	ko00000	COG1030 Membrane-bound serine protease (ClpP class)
MDKIOEFL_02221	4.35e-192	yqfA	-	-	S	-	-	-	UPF0365 protein
MDKIOEFL_02222	2.57e-78	yqfB	-	-	-	-	-	-	-
MDKIOEFL_02223	2.07e-60	yqfC	-	-	S	-	-	-	sporulation protein YqfC
MDKIOEFL_02224	1.21e-241	yqfD	-	-	S	ko:K06438	-	ko00000	Stage IV sporulation
MDKIOEFL_02225	4.99e-224	phoH	-	-	T	ko:K06217	-	ko00000	Phosphate starvation-inducible protein PhoH
MDKIOEFL_02227	0.0	yqfF	-	-	S	ko:K07037	-	ko00000	membrane-associated HD superfamily hydrolase
MDKIOEFL_02228	8.68e-106	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MDKIOEFL_02229	4.75e-80	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
MDKIOEFL_02230	6.71e-93	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
MDKIOEFL_02231	9.98e-215	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MDKIOEFL_02232	5.29e-27	-	-	-	S	-	-	-	YqzL-like protein
MDKIOEFL_02233	6.15e-186	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
MDKIOEFL_02234	2.12e-222	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
MDKIOEFL_02235	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
MDKIOEFL_02236	3.29e-144	ccpN	-	-	K	-	-	-	CBS domain
MDKIOEFL_02237	6.38e-191	yqfL	2.7.11.33, 2.7.4.28	-	S	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MDKIOEFL_02238	6.03e-114	yqxD	-	-	S	ko:K09768	-	ko00000	Belongs to the UPF0178 family
MDKIOEFL_02239	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MDKIOEFL_02240	2.79e-254	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MDKIOEFL_02241	1.61e-81	cccA	-	-	C	ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
MDKIOEFL_02242	9.4e-148	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
MDKIOEFL_02243	2.54e-267	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MDKIOEFL_02244	1.75e-226	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MDKIOEFL_02245	1.05e-48	yqfQ	-	-	S	-	-	-	YqfQ-like protein
MDKIOEFL_02246	1.09e-310	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MDKIOEFL_02247	1.04e-214	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MDKIOEFL_02248	3.01e-49	yqfT	-	-	S	-	-	-	Protein of unknown function (DUF2624)
MDKIOEFL_02249	3.83e-199	yqfU	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MDKIOEFL_02250	8.59e-107	zur	-	-	P	ko:K02076	-	ko00000,ko03000	Belongs to the Fur family
MDKIOEFL_02251	4.78e-141	yqfW	-	-	S	ko:K05967	-	ko00000	Belongs to the 5'(3')-deoxyribonucleotidase family
MDKIOEFL_02252	2.04e-81	yqfX	-	-	S	-	-	-	membrane
MDKIOEFL_02253	5.22e-257	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MDKIOEFL_02254	1.35e-61	yqfZ	-	-	M	ko:K06417	-	ko00000	LysM domain
MDKIOEFL_02255	1.58e-167	yqgB	-	-	S	-	-	-	Protein of unknown function (DUF1189)
MDKIOEFL_02256	8.25e-101	yqgC	-	-	S	ko:K09793	-	ko00000	protein conserved in bacteria
MDKIOEFL_02257	1.59e-148	sodA	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	radicals which are normally produced within the cells and which are toxic to biological systems
MDKIOEFL_02258	1.61e-292	yqgE	-	-	EGP	ko:K08222	-	ko00000,ko02000	Major facilitator superfamily
MDKIOEFL_02259	0.0	pbpA	-	-	M	ko:K21465,ko:K21466	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
MDKIOEFL_02260	2.61e-205	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
MDKIOEFL_02261	7.11e-203	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
MDKIOEFL_02262	1.51e-201	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
MDKIOEFL_02263	9.78e-190	pstBA	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MDKIOEFL_02264	1.57e-186	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MDKIOEFL_02265	1.09e-93	yqzC	-	-	S	-	-	-	YceG-like family
MDKIOEFL_02266	3.42e-68	yqzD	-	-	-	-	-	-	-
MDKIOEFL_02268	3.92e-248	yqgM	2.4.1.250	-	M	ko:K15521	-	ko00000,ko01000	Glycosyl transferases group 1
MDKIOEFL_02269	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
MDKIOEFL_02270	9.33e-136	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MDKIOEFL_02271	3.38e-14	yqgO	-	-	-	-	-	-	-
MDKIOEFL_02272	0.0	gluP	3.4.21.105	-	O	ko:K19225	-	ko00000,ko01000,ko01002	membrane protein (homolog of Drosophila rhomboid)
MDKIOEFL_02273	2.19e-44	yqgQ	-	-	S	-	-	-	Protein conserved in bacteria
MDKIOEFL_02274	2.31e-230	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
MDKIOEFL_02275	0.0	yqgS	2.7.8.20	-	M	ko:K01138,ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
MDKIOEFL_02276	1.19e-280	yqgT	3.4.19.11	-	E	ko:K01308	-	ko00000,ko01000,ko01002	Gamma-D-glutamyl-L-diamino acid endopeptidase
MDKIOEFL_02277	2.69e-256	yqgU	-	-	-	-	-	-	-
MDKIOEFL_02278	7.34e-66	yqgV	-	-	S	-	-	-	Thiamine-binding protein
MDKIOEFL_02279	1.91e-31	yqgW	-	-	S	-	-	-	Protein of unknown function (DUF2759)
MDKIOEFL_02280	1.3e-156	yqgX	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	COG0491 Zn-dependent hydrolases, including glyoxylases
MDKIOEFL_02281	1.46e-50	yqgY	-	-	S	-	-	-	Protein of unknown function (DUF2626)
MDKIOEFL_02282	7.79e-85	yqgZ	1.20.4.1	-	P	ko:K00537,ko:K16509	-	ko00000,ko01000	Belongs to the ArsC family
MDKIOEFL_02284	8.33e-191	yqhA	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MDKIOEFL_02285	2.01e-305	yqhB	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
MDKIOEFL_02286	1.51e-233	yqxL	-	-	P	-	-	-	Mg2 transporter protein
MDKIOEFL_02287	7.5e-06	-	-	-	S	-	-	-	Domain in cystathionine beta-synthase and other proteins.
MDKIOEFL_02288	5.23e-256	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MDKIOEFL_02289	2.5e-218	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	COG1459 Type II secretory pathway, component PulF
MDKIOEFL_02290	5.33e-63	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	Required for transformation and DNA binding
MDKIOEFL_02291	5.81e-86	gspH	-	-	NU	ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02035,ko02044	protein transport across the cell outer membrane
MDKIOEFL_02292	1.77e-78	comGE	-	-	-	ko:K02247	-	ko00000,ko00002,ko02044	-
MDKIOEFL_02293	7.11e-47	comGF	-	-	U	ko:K02246,ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
MDKIOEFL_02294	1.08e-56	-	-	-	S	ko:K02249	-	ko00000,ko00002,ko02044	ComG operon protein 7
MDKIOEFL_02295	4.9e-37	yqzE	-	-	S	-	-	-	YqzE-like protein
MDKIOEFL_02296	3.05e-69	yqzG	-	-	S	-	-	-	Protein of unknown function (DUF3889)
MDKIOEFL_02297	3.47e-150	yqxM	-	-	-	ko:K19433	-	ko00000	-
MDKIOEFL_02298	7.4e-98	sipW	3.4.21.89	-	U	ko:K13280	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase
MDKIOEFL_02299	1.28e-181	tasA_1	-	-	S	ko:K06336	-	ko00000,ko01002	Cell division protein FtsN
MDKIOEFL_02300	3.69e-72	sinR	-	-	K	ko:K19449	-	ko00000,ko03000	transcriptional
MDKIOEFL_02301	1.39e-33	sinI	-	-	S	ko:K06372	-	ko00000	Anti-repressor SinI
MDKIOEFL_02302	2.07e-193	yqhG	-	-	S	-	-	-	Bacterial protein YqhG of unknown function
MDKIOEFL_02303	0.0	yqhH	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
MDKIOEFL_02304	3.31e-262	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine
MDKIOEFL_02305	0.0	gcvPA	1.4.4.2	-	E	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MDKIOEFL_02306	0.0	gcvPB	1.4.4.2	-	E	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MDKIOEFL_02307	7.5e-83	yqhL	-	-	P	-	-	-	COG0607 Rhodanese-related sulfurtransferase
MDKIOEFL_02308	1.07e-202	lipM	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
MDKIOEFL_02309	1.97e-97	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
MDKIOEFL_02310	1.21e-210	yqhO	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
MDKIOEFL_02311	5.18e-81	yqhP	-	-	-	-	-	-	-
MDKIOEFL_02312	2.98e-220	yqhQ	-	-	S	-	-	-	Protein of unknown function (DUF1385)
MDKIOEFL_02313	8.02e-121	yqhR	-	-	S	-	-	-	Conserved membrane protein YqhR
MDKIOEFL_02314	1.17e-101	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
MDKIOEFL_02315	2.99e-249	yqhT	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
MDKIOEFL_02316	4.8e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MDKIOEFL_02317	6.96e-50	yqhV	-	-	S	-	-	-	Protein of unknown function (DUF2619)
MDKIOEFL_02318	8.22e-217	spoIIIAA	-	-	S	ko:K06390	-	ko00000	stage III sporulation protein AA
MDKIOEFL_02319	3.29e-110	spoIIIAB	-	-	S	ko:K06391	-	ko00000	Stage III sporulation protein
MDKIOEFL_02320	1.63e-39	spoIIIAC	-	-	S	ko:K06392	-	ko00000	stage III sporulation protein AC
MDKIOEFL_02321	1.93e-77	spoIIIAD	-	-	S	ko:K06393	-	ko00000	Stage III sporulation protein AD
MDKIOEFL_02322	2.19e-256	spoIIIAE	-	-	S	ko:K06394	-	ko00000	stage III sporulation protein AE
MDKIOEFL_02323	1.28e-131	spoIIIAF	-	-	S	ko:K06395	-	ko00000	Stage III sporulation protein AF (Spore_III_AF)
MDKIOEFL_02324	1.08e-148	spoIIIAG	-	-	S	ko:K06396	-	ko00000	stage III sporulation protein AG
MDKIOEFL_02325	9.92e-135	spoIIIAH	-	-	S	ko:K06397	-	ko00000	SpoIIIAH-like protein
MDKIOEFL_02326	3.21e-93	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MDKIOEFL_02327	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
MDKIOEFL_02328	1.65e-88	yqhY	-	-	S	-	-	-	protein conserved in bacteria
MDKIOEFL_02329	4.8e-86	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MDKIOEFL_02330	1.07e-200	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MDKIOEFL_02331	3.55e-312	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MDKIOEFL_02332	1.09e-51	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MDKIOEFL_02333	4.2e-209	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MDKIOEFL_02334	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MDKIOEFL_02335	1.77e-198	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	rRNA methylase
MDKIOEFL_02336	1.53e-102	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
MDKIOEFL_02337	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
MDKIOEFL_02338	1.26e-303	spoIVB	3.4.21.116	-	M	ko:K06399	-	ko00000,ko01000,ko01002	Stage IV sporulation protein B
MDKIOEFL_02339	1.89e-186	spo0A	-	-	KT	ko:K07699	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
MDKIOEFL_02341	1.15e-272	yqiG	-	-	C	-	-	-	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
MDKIOEFL_02342	2.26e-37	-	-	-	-	-	-	-	-
MDKIOEFL_02343	5.67e-139	lytC_1	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Cell wall hydrolase autolysin
MDKIOEFL_02344	3.39e-168	yqiK	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
MDKIOEFL_02345	1.91e-279	mmgA	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
MDKIOEFL_02346	2.69e-196	mmgB	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	Dehydrogenase
MDKIOEFL_02347	7.02e-268	mmgC	-	-	I	ko:K18244	-	ko00000,ko01000	acyl-CoA dehydrogenase
MDKIOEFL_02348	1.52e-263	mmgD	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
MDKIOEFL_02349	0.0	prpD	4.2.1.79	-	S	ko:K01720	ko00640,map00640	ko00000,ko00001,ko01000	2-methylcitrate dehydratase
MDKIOEFL_02350	5.09e-208	prpB	4.1.3.30, 5.4.2.9	-	G	ko:K01841,ko:K03417	ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MDKIOEFL_02351	1.56e-46	yqzF	-	-	S	-	-	-	Protein of unknown function (DUF2627)
MDKIOEFL_02352	0.0	bkdR	-	-	KT	-	-	-	Transcriptional regulator
MDKIOEFL_02353	5e-198	ptb	2.3.1.19	-	C	ko:K00634	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	phosphate butyryltransferase
MDKIOEFL_02354	1.92e-262	ldh	1.4.1.9	-	E	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
MDKIOEFL_02355	4.82e-255	buk	2.7.2.7	-	C	ko:K00929	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Belongs to the acetokinase family
MDKIOEFL_02356	0.0	bfmBC	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MDKIOEFL_02357	1.11e-237	bfmBAA	1.2.4.4	-	C	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MDKIOEFL_02358	4e-234	bfmBAB	1.2.4.4	-	C	ko:K00167,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MDKIOEFL_02359	1.47e-285	bkdB	2.3.1.12, 2.3.1.168	-	C	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MDKIOEFL_02360	6.38e-195	-	-	-	K	ko:K19575	-	ko00000,ko00002,ko03000	helix_turn_helix, mercury resistance
MDKIOEFL_02361	3.6e-266	norA	-	-	EGP	ko:K08153,ko:K19576,ko:K19578	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
MDKIOEFL_02362	1.21e-213	bmrU	-	-	I	-	-	-	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MDKIOEFL_02363	3.79e-101	yqiW	-	-	S	-	-	-	Belongs to the UPF0403 family
MDKIOEFL_02364	1.18e-174	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
MDKIOEFL_02365	8.94e-143	artQ	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
MDKIOEFL_02366	5.2e-166	artM	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
MDKIOEFL_02367	4.07e-220	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
MDKIOEFL_02368	9.84e-128	yqjB	-	-	S	-	-	-	protein conserved in bacteria
MDKIOEFL_02370	5.45e-94	mce	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0346 Lactoylglutathione lyase and related lyases
MDKIOEFL_02371	0.0	yqjD	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MDKIOEFL_02372	5.26e-259	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	COG2195 Di- and tripeptidases
MDKIOEFL_02373	1.57e-177	yqjF	-	-	S	ko:K09166	-	ko00000	Uncharacterized conserved protein (COG2071)
MDKIOEFL_02374	7.27e-179	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MDKIOEFL_02375	1.77e-32	yqzJ	-	-	-	-	-	-	-
MDKIOEFL_02376	1.84e-299	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MDKIOEFL_02377	0.0	gnd	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MDKIOEFL_02378	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MDKIOEFL_02379	6.29e-221	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MDKIOEFL_02380	8.59e-27	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
MDKIOEFL_02381	1.29e-186	yqjL	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MDKIOEFL_02382	1.21e-245	namA	1.6.99.1	-	C	ko:K00354	-	ko00000,ko01000	Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
MDKIOEFL_02383	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
MDKIOEFL_02384	1.13e-188	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MDKIOEFL_02385	1.33e-228	yqjP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
MDKIOEFL_02386	5.66e-184	yqjQ	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
MDKIOEFL_02387	0.0	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
MDKIOEFL_02388	5.43e-228	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
MDKIOEFL_02389	5.43e-95	yqjT	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MDKIOEFL_02391	3.24e-286	yqjV	-	-	G	-	-	-	Major Facilitator Superfamily
MDKIOEFL_02393	4.03e-304	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MDKIOEFL_02394	9.27e-66	yqiX	-	-	S	-	-	-	YolD-like protein
MDKIOEFL_02395	5.46e-113	yqjY	-	-	K	ko:K06977	-	ko00000	acetyltransferase
MDKIOEFL_02396	6.7e-73	yqjZ	-	-	S	-	-	-	enzyme involved in biosynthesis of extracellular polysaccharides
MDKIOEFL_02397	1.13e-248	yqkA	-	-	K	-	-	-	GrpB protein
MDKIOEFL_02398	6.17e-73	yqkB	-	-	S	-	-	-	Belongs to the HesB IscA family
MDKIOEFL_02399	1.12e-53	yqkC	-	-	S	-	-	-	Protein of unknown function (DUF2552)
MDKIOEFL_02400	1.25e-219	yqkD	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
MDKIOEFL_02401	6.61e-26	yqkE	-	-	S	-	-	-	Protein of unknown function (DUF3886)
MDKIOEFL_02402	1.04e-214	yqkF	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
MDKIOEFL_02403	8.21e-10	-	-	-	S	-	-	-	Protein of unknown function (DUF3936)
MDKIOEFL_02404	4.07e-120	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
MDKIOEFL_02405	2.93e-280	yqxK	-	-	L	-	-	-	DNA helicase
MDKIOEFL_02406	3.18e-77	ansR	-	-	K	-	-	-	Transcriptional regulator
MDKIOEFL_02407	1.77e-238	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase
MDKIOEFL_02408	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Aspartate ammonia-lyase
MDKIOEFL_02409	0.0	mleN	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
MDKIOEFL_02410	3.95e-309	mleA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
MDKIOEFL_02411	7.27e-42	yqkK	-	-	-	-	-	-	-
MDKIOEFL_02412	5.61e-139	spoIIM	-	-	S	ko:K06384	-	ko00000	Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
MDKIOEFL_02413	2.26e-104	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
MDKIOEFL_02414	2.73e-50	-	-	-	S	-	-	-	Protein of unknown function (DUF4227)
MDKIOEFL_02415	2.26e-213	xerD	-	-	L	ko:K04763	-	ko00000,ko03036	recombinase XerD
MDKIOEFL_02416	6.8e-294	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
MDKIOEFL_02417	5.66e-190	punA	2.4.2.1, 2.4.2.28	-	F	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	ko00000,ko00001,ko00002,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MDKIOEFL_02418	9.65e-271	dacF	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MDKIOEFL_02419	1.22e-75	spoIIAA	-	-	T	ko:K06378	-	ko00000	Belongs to the anti-sigma-factor antagonist family
MDKIOEFL_02420	6.78e-100	spoIIAB	2.7.11.1	-	F	ko:K06379	-	ko00000,ko01000	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
MDKIOEFL_02421	1.18e-174	sigF	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MDKIOEFL_02422	1.15e-143	spoVAA	-	-	S	ko:K06403	-	ko00000	Stage V sporulation protein AA
MDKIOEFL_02423	5.43e-90	spoVAB	-	-	S	ko:K06404	-	ko00000	Stage V sporulation protein AB
MDKIOEFL_02424	6.71e-102	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
MDKIOEFL_02425	6.02e-246	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
MDKIOEFL_02426	2.15e-75	spoVAEB	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
MDKIOEFL_02427	1.85e-143	-	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
MDKIOEFL_02428	0.0	spoVAF	-	-	EG	ko:K06408	-	ko00000	Stage V sporulation protein AF
MDKIOEFL_02429	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MDKIOEFL_02430	3.12e-192	ypuA	-	-	S	-	-	-	Secreted protein
MDKIOEFL_02431	1.23e-105	ppiB	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MDKIOEFL_02437	2.61e-34	ppiB	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MDKIOEFL_02439	6.11e-44	ypzJ	-	-	S	ko:K07069	-	ko00000	nucleic-acid-binding protein containing a Zn-ribbon domain
MDKIOEFL_02440	1.18e-132	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MDKIOEFL_02441	5.98e-72	ypuD	-	-	-	-	-	-	-
MDKIOEFL_02442	2.07e-260	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MDKIOEFL_02443	2.5e-147	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
MDKIOEFL_02444	1.48e-290	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MDKIOEFL_02445	8.41e-107	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MDKIOEFL_02446	1.12e-83	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MDKIOEFL_02447	1.45e-119	ypuF	-	-	S	ko:K09763	-	ko00000	Domain of unknown function (DUF309)
MDKIOEFL_02448	1.33e-167	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MDKIOEFL_02449	2e-135	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MDKIOEFL_02450	2.92e-126	ypuI	-	-	S	-	-	-	Protein of unknown function (DUF3907)
MDKIOEFL_02451	1.18e-272	dacB	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MDKIOEFL_02452	7.57e-135	spmA	-	-	S	ko:K06373	-	ko00000	Spore maturation protein
MDKIOEFL_02453	8.62e-114	spmB	-	-	S	ko:K06374	-	ko00000	Spore maturation protein
MDKIOEFL_02454	4.45e-169	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MDKIOEFL_02455	2.05e-126	resA	-	-	CO	-	-	-	Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
MDKIOEFL_02456	0.0	resB	-	-	O	ko:K07399	-	ko00000	COG1333 ResB protein required for cytochrome c biosynthesis
MDKIOEFL_02457	1.1e-277	resC	-	-	O	-	-	-	'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
MDKIOEFL_02458	1.69e-171	resD	-	-	T	ko:K07775	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MDKIOEFL_02459	0.0	resE	2.7.13.3	-	T	ko:K07651	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MDKIOEFL_02460	1.08e-133	sigX	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MDKIOEFL_02461	5.59e-236	rsiX	-	-	-	-	-	-	-
MDKIOEFL_02462	1.32e-171	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MDKIOEFL_02463	0.0	serA	1.1.1.399, 1.1.1.95	-	E	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MDKIOEFL_02464	3.07e-122	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MDKIOEFL_02465	8.35e-55	fer	-	-	C	ko:K05337	-	ko00000	Ferredoxin
MDKIOEFL_02466	2.03e-251	ypbB	5.1.3.1	-	S	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	protein conserved in bacteria
MDKIOEFL_02467	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
MDKIOEFL_02468	2.92e-127	ypbD	-	-	S	ko:K07052	-	ko00000	metal-dependent membrane protease
MDKIOEFL_02469	1.18e-122	ypbE	-	-	M	-	-	-	Lysin motif
MDKIOEFL_02470	1.42e-106	ypbF	-	-	S	-	-	-	Protein of unknown function (DUF2663)
MDKIOEFL_02471	4.33e-188	ypbG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
MDKIOEFL_02472	5.56e-136	mecB	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MDKIOEFL_02473	1.42e-308	gudB	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
MDKIOEFL_02474	1.48e-223	ypdA	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	COG0492 Thioredoxin reductase
MDKIOEFL_02475	4.33e-154	prsW	-	-	S	-	-	-	Involved in the degradation of specific anti-sigma factors
MDKIOEFL_02476	6.93e-208	sleB	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Spore cortex-lytic enzyme
MDKIOEFL_02477	0.0	ypeB	-	-	H	ko:K06313	-	ko00000	sporulation protein
MDKIOEFL_02478	1.81e-141	ypfA	-	-	M	-	-	-	Flagellar protein YcgR
MDKIOEFL_02479	2.48e-32	-	-	-	S	-	-	-	Family of unknown function (DUF5359)
MDKIOEFL_02480	7.9e-144	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
MDKIOEFL_02481	7.8e-262	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
MDKIOEFL_02482	3.28e-235	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MDKIOEFL_02483	1.13e-11	-	-	-	S	-	-	-	YpzI-like protein
MDKIOEFL_02484	4.52e-133	yphA	-	-	-	-	-	-	-
MDKIOEFL_02485	4.35e-207	yphB	-	-	S	ko:K05739	-	ko00000	YIEGIA protein
MDKIOEFL_02486	5.91e-38	ypzH	-	-	-	-	-	-	-
MDKIOEFL_02487	1.72e-315	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
MDKIOEFL_02488	1.05e-229	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
MDKIOEFL_02489	7.09e-27	yphE	-	-	S	-	-	-	Protein of unknown function (DUF2768)
MDKIOEFL_02490	4.31e-176	yphF	-	-	-	-	-	-	-
MDKIOEFL_02491	0.0	spoIVA	-	-	S	ko:K06398	-	ko00000	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MDKIOEFL_02492	1.07e-57	hbs	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MDKIOEFL_02493	4.41e-131	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
MDKIOEFL_02494	5.13e-46	mtrB	-	-	K	ko:K06285	-	ko00000,ko03000	Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
MDKIOEFL_02495	8.72e-178	hepS	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
MDKIOEFL_02496	1.34e-169	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MDKIOEFL_02497	4.09e-249	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MDKIOEFL_02498	2.17e-104	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
MDKIOEFL_02499	5.03e-181	cheR	2.1.1.80	-	NT	ko:K00575	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko01000,ko02035	COG1352 Methylase of chemotaxis methyl-accepting proteins
MDKIOEFL_02500	1.44e-277	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MDKIOEFL_02501	5.72e-263	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MDKIOEFL_02502	9.82e-84	aroH	5.4.99.5	-	E	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
MDKIOEFL_02503	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MDKIOEFL_02504	5e-229	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MDKIOEFL_02505	4.88e-144	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
MDKIOEFL_02506	1.57e-150	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
MDKIOEFL_02507	3.64e-292	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MDKIOEFL_02508	1.82e-184	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MDKIOEFL_02509	1.44e-255	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MDKIOEFL_02510	1.21e-264	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
MDKIOEFL_02511	1.35e-299	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MDKIOEFL_02512	7.18e-297	ypiA	-	-	S	-	-	-	COG0457 FOG TPR repeat
MDKIOEFL_02513	7.45e-129	ypiB	-	-	S	-	-	-	Belongs to the UPF0302 family
MDKIOEFL_02514	5.55e-100	ypiF	-	-	S	-	-	-	Protein of unknown function (DUF2487)
MDKIOEFL_02515	3.35e-126	qcrA	-	-	C	ko:K03886	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Menaquinol-cytochrome c reductase
MDKIOEFL_02516	8.76e-166	qcrB	-	-	C	ko:K03887	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	COG1290 Cytochrome b subunit of the bc complex
MDKIOEFL_02517	5.71e-191	qcrC	-	-	C	ko:K03888	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Menaquinol-cytochrome c reductase cytochrome b c subunit
MDKIOEFL_02518	1.2e-127	ypjA	-	-	S	-	-	-	membrane
MDKIOEFL_02519	2.79e-182	ypjB	-	-	S	-	-	-	sporulation protein
MDKIOEFL_02520	3.7e-200	ypjC	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MDKIOEFL_02521	1.01e-73	ypjD	-	-	S	-	-	-	Nucleotide pyrophosphohydrolase
MDKIOEFL_02522	5.66e-188	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MDKIOEFL_02523	1.03e-92	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
MDKIOEFL_02524	1.89e-166	bshB1	-	-	S	ko:K01463	-	ko00000,ko01000	proteins, LmbE homologs
MDKIOEFL_02525	8.18e-266	bshA	-	GT4	M	ko:K00754	-	ko00000,ko01000	N-acetyl-alpha-D-glucosaminyl L-malate synthase
MDKIOEFL_02526	4.32e-278	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MDKIOEFL_02527	4.87e-234	birA	6.3.4.15	-	K	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MDKIOEFL_02528	1.98e-193	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
MDKIOEFL_02529	5.47e-200	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MDKIOEFL_02530	4.16e-85	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MDKIOEFL_02531	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
MDKIOEFL_02532	1.52e-32	ypmA	-	-	S	-	-	-	Protein of unknown function (DUF4264)
MDKIOEFL_02533	2.66e-102	ypmB	-	-	S	-	-	-	protein conserved in bacteria
MDKIOEFL_02534	2.08e-283	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
MDKIOEFL_02535	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	asparaginyl-tRNA
MDKIOEFL_02536	1.56e-163	dnaD	-	-	L	ko:K02086	-	ko00000	DNA replication protein DnaD
MDKIOEFL_02537	3.57e-158	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MDKIOEFL_02538	1.67e-120	ypoC	-	-	-	-	-	-	-
MDKIOEFL_02539	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
MDKIOEFL_02540	3.2e-150	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MDKIOEFL_02541	1.7e-236	yppC	-	-	S	-	-	-	Protein of unknown function (DUF2515)
MDKIOEFL_02544	7.9e-10	yppE	-	-	S	-	-	-	Bacterial domain of unknown function (DUF1798)
MDKIOEFL_02545	9.21e-11	-	-	-	S	-	-	-	YppF-like protein
MDKIOEFL_02546	1.45e-66	yppG	-	-	S	-	-	-	YppG-like protein
MDKIOEFL_02547	2.06e-93	hspX	-	-	O	ko:K06335,ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
MDKIOEFL_02548	5.3e-110	ypqE	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	COG2190 Phosphotransferase system IIA components
MDKIOEFL_02549	0.0	yprA	-	-	L	ko:K06877	-	ko00000	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
MDKIOEFL_02550	5.68e-298	yprB	-	-	L	ko:K07502	-	ko00000	RNase_H superfamily
MDKIOEFL_02551	2.4e-128	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
MDKIOEFL_02552	2.97e-60	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MDKIOEFL_02553	1.16e-285	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
MDKIOEFL_02555	0.0	ypvA	3.6.4.12	-	KL	ko:K03722	-	ko00000,ko01000,ko03400	COG1199 Rad3-related DNA helicases
MDKIOEFL_02556	5.63e-177	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MDKIOEFL_02557	2.96e-203	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
MDKIOEFL_02558	7.8e-238	kdgR	-	-	K	ko:K02525	-	ko00000,ko03000	transcriptional
MDKIOEFL_02559	2.83e-237	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0524 Sugar kinases, ribokinase family
MDKIOEFL_02560	1.71e-131	kdgA	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	2-dehydro-3-deoxy-phosphogluconate aldolase
MDKIOEFL_02561	4.09e-224	kdgT	-	-	P	ko:K02526	-	ko00000,ko02000	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
MDKIOEFL_02562	0.0	ypwA	3.4.17.19	-	E	ko:K01299	-	ko00000,ko01000,ko01002	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MDKIOEFL_02563	2.73e-127	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MDKIOEFL_02564	8.24e-290	pbuX	-	-	F	ko:K03458,ko:K16169,ko:K16170	-	ko00000,ko02000	xanthine
MDKIOEFL_02565	2.63e-265	bcsA	-	-	Q	ko:K16167	-	ko00000,ko01008	Naringenin-chalcone synthase
MDKIOEFL_02566	3.33e-113	ypbQ	-	-	S	ko:K16168	-	ko00000,ko01008	protein conserved in bacteria
MDKIOEFL_02568	0.0	ypbR	-	-	S	-	-	-	Dynamin family
MDKIOEFL_02569	6.77e-51	ypbS	-	-	S	-	-	-	Protein of unknown function (DUF2533)
MDKIOEFL_02570	1.08e-11	-	-	-	-	-	-	-	-
MDKIOEFL_02571	2.26e-213	ypcP	-	-	L	-	-	-	5'3' exonuclease
MDKIOEFL_02572	5.23e-05	-	-	-	-	ko:K06429	-	ko00000	-
MDKIOEFL_02573	7.64e-88	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease
MDKIOEFL_02574	2.12e-155	ypdP	-	-	S	ko:K09125	-	ko00000	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MDKIOEFL_02575	1.1e-160	ypeP	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	COG0328 Ribonuclease HI
MDKIOEFL_02576	1.54e-37	ypeQ	-	-	S	-	-	-	Zinc-finger
MDKIOEFL_02577	1.05e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF2564)
MDKIOEFL_02578	1.17e-22	degR	-	-	-	-	-	-	-
MDKIOEFL_02579	5.12e-42	cspD	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
MDKIOEFL_02580	1.28e-276	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
MDKIOEFL_02581	1.23e-224	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MDKIOEFL_02582	9.67e-113	bsaA	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
MDKIOEFL_02583	1.99e-139	yagB	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
MDKIOEFL_02584	4.68e-203	ypgR	-	-	C	-	-	-	COG0694 Thioredoxin-like proteins and domains
MDKIOEFL_02585	0.0	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
MDKIOEFL_02586	9.69e-99	yphP	-	-	S	-	-	-	Belongs to the UPF0403 family
MDKIOEFL_02587	3.56e-186	ypiP	-	-	AJ	-	-	-	Putative SAM-dependent methyltransferase
MDKIOEFL_02588	3.47e-148	ypjP	-	-	S	-	-	-	YpjP-like protein
MDKIOEFL_02589	1.27e-120	ltrC	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
MDKIOEFL_02590	3.9e-121	dfrA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MDKIOEFL_02591	7.48e-140	ypkP	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MDKIOEFL_02592	8.03e-143	yplQ	-	-	S	ko:K11068	-	ko00000,ko02042	protein, Hemolysin III
MDKIOEFL_02593	1.57e-233	yplP	-	-	K	-	-	-	Transcriptional regulator
MDKIOEFL_02594	3.64e-310	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MDKIOEFL_02595	1.75e-52	ypmP	-	-	S	-	-	-	Protein of unknown function (DUF2535)
MDKIOEFL_02596	5.58e-140	ypmQ	-	-	S	ko:K07152	-	ko00000,ko03029	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
MDKIOEFL_02597	2.58e-178	ypmR	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MDKIOEFL_02598	5.59e-128	ypmS	-	-	S	-	-	-	protein conserved in bacteria
MDKIOEFL_02599	8.69e-40	ypmT	-	-	S	-	-	-	Uncharacterized ympT
MDKIOEFL_02600	7.03e-290	mepA	-	-	V	-	-	-	MATE efflux family protein
MDKIOEFL_02601	4.14e-94	ypoP	-	-	K	-	-	-	transcriptional
MDKIOEFL_02602	8.09e-132	msrB	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MDKIOEFL_02603	2.9e-102	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
MDKIOEFL_02604	1.66e-157	-	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
MDKIOEFL_02605	9.41e-279	phy	3.1.3.8	-	I	ko:K01083	ko00562,map00562	ko00000,ko00001,ko01000	Myo-inositol-hexaphosphate 3-phosphohydrolase
MDKIOEFL_02606	2.69e-227	cgeB	-	-	S	ko:K06320	-	ko00000	Spore maturation protein
MDKIOEFL_02607	1.79e-82	cgeA	-	-	-	ko:K06319	-	ko00000	-
MDKIOEFL_02608	1.45e-57	cgeC	-	-	-	ko:K06321	-	ko00000	-
MDKIOEFL_02609	0.0	cgeD	-	-	M	ko:K06322	-	ko00000	maturation of the outermost layer of the spore
MDKIOEFL_02610	3.27e-183	yiiD	-	-	K	ko:K06323	-	ko00000	acetyltransferase
MDKIOEFL_02612	9.36e-317	yodT	-	-	H	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MDKIOEFL_02613	1.97e-160	atoD	2.8.3.8, 2.8.3.9	-	I	ko:K01034	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MDKIOEFL_02614	9.44e-153	atoA	2.8.3.8, 2.8.3.9	-	I	ko:K01035	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MDKIOEFL_02615	0.0	yodQ	3.5.1.16, 3.5.1.18	-	E	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetylornithine deacetylase
MDKIOEFL_02616	5.27e-197	yodP	2.3.1.264	-	K	ko:K21935	-	ko00000,ko01000	Acetyltransferase (GNAT) family
MDKIOEFL_02617	0.0	kamA	5.4.3.2	-	E	ko:K01843	ko00310,map00310	ko00000,ko00001,ko01000	lysine 2,3-aminomutase
MDKIOEFL_02618	3.44e-63	yokU	-	-	S	-	-	-	YokU-like protein, putative antitoxin
MDKIOEFL_02619	7.3e-50	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
MDKIOEFL_02620	7.44e-159	yodN	-	-	-	-	-	-	-
MDKIOEFL_02622	5.18e-34	yozD	-	-	S	-	-	-	YozD-like protein
MDKIOEFL_02623	1.35e-136	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
MDKIOEFL_02624	1.17e-71	yodL	-	-	S	-	-	-	YodL-like
MDKIOEFL_02625	2.08e-12	-	-	-	-	-	-	-	-
MDKIOEFL_02626	1.68e-163	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
MDKIOEFL_02627	1.33e-189	yodJ	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
MDKIOEFL_02628	4.86e-41	yodI	-	-	-	-	-	-	-
MDKIOEFL_02629	3.03e-166	yodH	-	-	Q	-	-	-	Methyltransferase
MDKIOEFL_02630	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
MDKIOEFL_02631	0.0	yodF	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MDKIOEFL_02632	2.36e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF3311)
MDKIOEFL_02633	1.38e-222	yodE	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
MDKIOEFL_02634	2.64e-146	yahD	-	-	S	ko:K06999	-	ko00000	Carboxylesterase
MDKIOEFL_02635	1.11e-139	yodC	-	-	C	-	-	-	nitroreductase
MDKIOEFL_02636	2.63e-73	yodB	-	-	K	-	-	-	transcriptional
MDKIOEFL_02637	3.97e-84	iolK	-	-	S	-	-	-	tautomerase
MDKIOEFL_02638	7.59e-289	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
MDKIOEFL_02639	5.59e-14	-	-	-	-	-	-	-	-
MDKIOEFL_02640	2.88e-103	yozR	-	-	S	-	-	-	COG0071 Molecular chaperone (small heat shock protein)
MDKIOEFL_02641	2.33e-207	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	-transporter
MDKIOEFL_02642	1.85e-58	-	-	-	-	-	-	-	-
MDKIOEFL_02643	2.32e-79	yojF	-	-	S	-	-	-	Protein of unknown function (DUF1806)
MDKIOEFL_02644	3.71e-161	yojG	-	-	S	ko:K22135	-	ko00000,ko01000	deacetylase
MDKIOEFL_02645	6.85e-192	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MDKIOEFL_02646	2.06e-313	norM	-	-	V	ko:K03327	-	ko00000,ko02000	Multidrug efflux pump
MDKIOEFL_02648	3.54e-140	dacB	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MDKIOEFL_02649	7.66e-292	yojK	-	-	CG	-	-	-	UDP-glucoronosyl and UDP-glucosyl transferase
MDKIOEFL_02650	1.07e-266	-	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
MDKIOEFL_02651	3.62e-142	sodC	1.15.1.1	-	P	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	ko00000,ko00001,ko01000	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MDKIOEFL_02652	1.33e-207	yojN	-	-	S	ko:K04748	-	ko00000	ATPase family associated with various cellular activities (AAA)
MDKIOEFL_02653	0.0	yojO	-	-	P	-	-	-	Von Willebrand factor
MDKIOEFL_02654	0.0	odhA	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
MDKIOEFL_02655	2.59e-264	odhB	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
MDKIOEFL_02656	3.31e-214	yocS	-	-	S	ko:K03453	-	ko00000	-transporter
MDKIOEFL_02657	4.35e-300	yocR	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MDKIOEFL_02658	3.91e-211	sodF	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Superoxide dismutase
MDKIOEFL_02659	0.0	sqhC	4.2.1.137	-	I	ko:K18115	-	ko00000,ko01000	COG1657 Squalene cyclase
MDKIOEFL_02660	0.0	dhaS	1.2.1.3, 1.2.1.39	-	C	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MDKIOEFL_02661	1.91e-42	yozC	-	-	-	-	-	-	-
MDKIOEFL_02662	2.17e-74	yozO	-	-	S	-	-	-	Bacterial PH domain
MDKIOEFL_02663	1.83e-49	yocN	-	-	-	-	-	-	-
MDKIOEFL_02664	2.94e-55	yozN	-	-	-	-	-	-	-
MDKIOEFL_02665	5.43e-114	yocM	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
MDKIOEFL_02666	3.93e-41	-	-	-	-	-	-	-	-
MDKIOEFL_02667	4.29e-70	yocL	-	-	-	-	-	-	-
MDKIOEFL_02668	2.87e-107	yocK	-	-	T	-	-	-	general stress protein
MDKIOEFL_02669	1.46e-147	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MDKIOEFL_02670	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
MDKIOEFL_02671	6.78e-174	yocH	-	-	M	-	-	-	COG1388 FOG LysM repeat
MDKIOEFL_02672	4.71e-135	desR	-	-	T	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MDKIOEFL_02673	4.09e-251	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MDKIOEFL_02674	3.99e-258	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
MDKIOEFL_02675	2.25e-239	yocD	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	peptidase S66
MDKIOEFL_02676	1.32e-122	yocC	-	-	-	-	-	-	-
MDKIOEFL_02677	2.6e-185	-	-	-	-	-	-	-	-
MDKIOEFL_02678	3.97e-119	yozB	-	-	S	ko:K08976	-	ko00000	membrane
MDKIOEFL_02679	9.39e-157	yocA	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MDKIOEFL_02680	8.12e-69	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	transcriptional
MDKIOEFL_02681	5.2e-121	yobW	-	-	-	-	-	-	-
MDKIOEFL_02682	5.81e-222	yobV	-	-	K	-	-	-	WYL domain
MDKIOEFL_02683	8.64e-112	-	-	-	K	-	-	-	Bacterial transcription activator, effector binding domain
MDKIOEFL_02684	4.49e-168	yobT	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
MDKIOEFL_02685	1.53e-127	yobS	-	-	K	-	-	-	Transcriptional regulator
MDKIOEFL_02686	7.42e-176	-	-	-	J	-	-	-	FR47-like protein
MDKIOEFL_02687	3.96e-170	yobQ	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
MDKIOEFL_02688	9e-72	csaA	-	-	J	ko:K06878	-	ko00000	tRNA-binding protein
MDKIOEFL_02689	0.0	iaaM	1.4.3.4	-	E	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	ko00000,ko00001,ko00002,ko01000	COG1231 Monoamine oxidase
MDKIOEFL_02690	9e-116	yokH	-	-	G	-	-	-	SMI1 / KNR4 family
MDKIOEFL_02691	3.28e-21	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MDKIOEFL_02692	1.95e-26	-	-	-	-	-	-	-	-
MDKIOEFL_02694	7.88e-135	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
MDKIOEFL_02696	4.46e-23	-	-	-	-	-	-	-	-
MDKIOEFL_02697	1.32e-85	yoaQ	-	-	S	-	-	-	Evidence 4 Homologs of previously reported genes of
MDKIOEFL_02698	1.8e-97	-	-	-	-	-	-	-	-
MDKIOEFL_02700	2.46e-10	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
MDKIOEFL_02701	2.88e-105	yoaW	-	-	-	-	-	-	-
MDKIOEFL_02702	4.01e-36	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
MDKIOEFL_02703	6.23e-131	-	-	-	S	-	-	-	Domain of unknown function (DUF3885)
MDKIOEFL_02704	1.32e-66	ynaF	-	-	-	-	-	-	-
MDKIOEFL_02706	2.45e-11	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
MDKIOEFL_02711	1.83e-64	-	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
MDKIOEFL_02712	4.54e-48	-	-	-	-	-	-	-	-
MDKIOEFL_02714	2.11e-49	-	-	-	S	-	-	-	TM2 domain
MDKIOEFL_02715	7.53e-157	xlnB	3.2.1.8	-	G	ko:K01181	-	ko00000,ko01000	Glycosyl hydrolases family 11
MDKIOEFL_02716	0.0	pps	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphoenolpyruvate synthase
MDKIOEFL_02719	1.04e-214	penP	3.5.2.6	-	V	ko:K17836,ko:K18766	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	beta-lactamase
MDKIOEFL_02720	3.43e-147	lin0465	-	-	S	-	-	-	DJ-1/PfpI family
MDKIOEFL_02721	3.26e-101	yoaW	-	-	-	-	-	-	-
MDKIOEFL_02722	2.6e-201	yoaV	-	-	EG	-	-	-	EamA-like transporter family
MDKIOEFL_02723	2.23e-201	yoaU	-	-	K	-	-	-	LysR substrate binding domain
MDKIOEFL_02724	9.84e-192	yoaT	-	-	S	-	-	-	Protein of unknown function (DUF817)
MDKIOEFL_02725	4.17e-40	yozG	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
MDKIOEFL_02726	9.24e-98	yoaS	-	-	S	-	-	-	Protein of unknown function (DUF2975)
MDKIOEFL_02727	1.04e-217	yoaR	-	-	V	-	-	-	vancomycin resistance protein
MDKIOEFL_02728	1.53e-112	-	-	-	-	-	-	-	-
MDKIOEFL_02729	3.64e-23	yoaP	-	-	K	-	-	-	YoaP-like
MDKIOEFL_02731	3.62e-292	oxdD	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
MDKIOEFL_02734	5.08e-171	yoqW	-	-	S	-	-	-	Belongs to the SOS response-associated peptidase family
MDKIOEFL_02735	5e-253	-	4.2.2.10	-	G	ko:K01732	-	ko00000,ko01000	Amb_all
MDKIOEFL_02736	1.79e-145	yoaK	-	-	S	-	-	-	Membrane
MDKIOEFL_02737	2.61e-171	yoaJ	-	-	G	ko:K20628	-	ko00000	Endoglucanase C-terminal domain subunit and related proteins
MDKIOEFL_02738	0.0	yoaI	1.14.14.9	-	Q	ko:K00483	ko00350,ko01120,ko01220,map00350,map01120,map01220	ko00000,ko00001,ko01000	COG2368 Aromatic ring hydroxylase
MDKIOEFL_02739	3.89e-283	yoaH	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	methyl-accepting chemotaxis protein
MDKIOEFL_02740	2.99e-55	-	-	-	S	-	-	-	Protein of unknown function (DUF4025)
MDKIOEFL_02741	1.25e-20	-	-	-	-	-	-	-	-
MDKIOEFL_02742	1.17e-12	-	-	-	-	-	-	-	-
MDKIOEFL_02743	3.99e-114	degA	-	-	K	-	-	-	Transcriptional regulator
MDKIOEFL_02744	3.73e-193	-	4.2.1.44	-	G	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Xylose isomerase-like TIM barrel
MDKIOEFL_02745	3.41e-259	-	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
MDKIOEFL_02746	4.76e-215	-	-	-	EGP	ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MDKIOEFL_02747	3.48e-43	yoaF	-	-	-	-	-	-	-
MDKIOEFL_02748	0.0	yoaE	-	-	C	-	-	-	belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MDKIOEFL_02749	1.37e-233	yoaD	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MDKIOEFL_02750	0.0	lsrK	2.7.1.189	-	G	ko:K11216	ko02024,map02024	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
MDKIOEFL_02751	2.24e-300	yoaB	-	-	EGP	-	-	-	the major facilitator superfamily
MDKIOEFL_02752	6.7e-104	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MDKIOEFL_02753	7.41e-179	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
MDKIOEFL_02754	1.02e-120	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
MDKIOEFL_02755	1.2e-165	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
MDKIOEFL_02756	1.83e-119	yoaA	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MDKIOEFL_02757	1.48e-173	yoxB	-	-	-	-	-	-	-
MDKIOEFL_02758	9.43e-52	yoxC	-	-	S	-	-	-	Bacterial protein of unknown function (DUF948)
MDKIOEFL_02759	2.28e-159	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
MDKIOEFL_02760	5.37e-79	rtp	-	-	K	-	-	-	Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
MDKIOEFL_02761	2.72e-185	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MDKIOEFL_02762	5.49e-261	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MDKIOEFL_02763	2.61e-205	gltC	-	-	K	ko:K09681	-	ko00000,ko03000	Transcriptional regulator
MDKIOEFL_02764	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
MDKIOEFL_02765	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
MDKIOEFL_02766	1.14e-176	yogA	-	-	C	ko:K13955	-	ko00000	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
MDKIOEFL_02767	1.41e-29	yogA	-	-	C	ko:K13955	-	ko00000	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
MDKIOEFL_02768	3.99e-197	gltR1	-	-	K	ko:K21959	-	ko00000,ko03000	Transcriptional regulator
MDKIOEFL_02769	0.0	ggt	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
MDKIOEFL_02770	1.92e-46	yoeD	-	-	G	-	-	-	Helix-turn-helix domain
MDKIOEFL_02771	1.14e-124	-	-	-	L	-	-	-	Integrase
MDKIOEFL_02773	7.14e-128	yoeB	-	-	S	-	-	-	IseA DL-endopeptidase inhibitor
MDKIOEFL_02774	9.8e-313	yoeA	-	-	V	-	-	-	MATE efflux family protein
MDKIOEFL_02775	5.75e-242	yoxA	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
MDKIOEFL_02776	0.0	dacC	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
MDKIOEFL_02777	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDKIOEFL_02778	0.0	-	-	-	Q	ko:K15665	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDKIOEFL_02779	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDKIOEFL_02780	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDKIOEFL_02781	0.0	-	6.3.2.14	-	Q	ko:K02364,ko:K15656,ko:K15668	ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024	ko00000,ko00001,ko01000,ko01008	amino acid activation for nonribosomal peptide biosynthetic process
MDKIOEFL_02782	2.89e-82	yngL	-	-	S	-	-	-	Protein of unknown function (DUF1360)
MDKIOEFL_02783	0.0	yngK	-	-	T	-	-	-	Glycosyl hydrolase-like 10
MDKIOEFL_02784	2.12e-31	-	-	-	S	-	-	-	Family of unknown function (DUF5367)
MDKIOEFL_02785	3.09e-267	yngJ	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
MDKIOEFL_02786	0.0	yngI	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MDKIOEFL_02787	8.43e-316	yngH	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase
MDKIOEFL_02788	2.4e-41	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin carboxyl carrier protein
MDKIOEFL_02789	9.56e-212	yngG	4.1.3.4	-	E	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA lyase
MDKIOEFL_02790	1.42e-173	yngF	-	-	I	-	-	-	Belongs to the enoyl-CoA hydratase isomerase family
MDKIOEFL_02791	0.0	yngE	-	-	I	-	-	-	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MDKIOEFL_02792	1.28e-296	yngD	-	-	S	ko:K07097	-	ko00000	phosphohydrolase (DHH superfamily)
MDKIOEFL_02793	2.01e-134	yngC	-	-	S	-	-	-	membrane-associated protein
MDKIOEFL_02794	2.74e-210	yngB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
MDKIOEFL_02795	1.72e-103	yngA	-	-	S	-	-	-	membrane
MDKIOEFL_02796	0.0	xynD	3.2.1.55	CBM6,GH43	G	ko:K15921	ko00520,map00520	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
MDKIOEFL_02797	9.85e-317	ynfF	3.2.1.136	GH5	M	ko:K15924	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 30 family
MDKIOEFL_02799	0.0	bglC5	3.2.1.4	GH5,GH9	G	ko:K01179	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	PFAM glycoside hydrolase family 5
MDKIOEFL_02800	0.0	alsT	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
MDKIOEFL_02801	8.74e-75	ynfC	-	-	-	-	-	-	-
MDKIOEFL_02802	1.82e-18	-	-	-	-	-	-	-	-
MDKIOEFL_02803	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MDKIOEFL_02804	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MDKIOEFL_02805	1.21e-90	yneT	-	-	S	ko:K06929	-	ko00000	CoA-binding protein
MDKIOEFL_02806	5.48e-122	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MDKIOEFL_02807	8.97e-65	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
MDKIOEFL_02808	9.46e-71	yneQ	-	-	-	-	-	-	-
MDKIOEFL_02809	4.02e-95	yneP	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
MDKIOEFL_02810	3.83e-47	tlp	-	-	S	ko:K06434	-	ko00000	Belongs to the Tlp family
MDKIOEFL_02812	9.26e-10	-	-	-	S	-	-	-	Fur-regulated basic protein B
MDKIOEFL_02813	7.25e-118	yneN	-	-	CO	-	-	-	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MDKIOEFL_02814	0.0	citB	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MDKIOEFL_02815	3.27e-21	sspO	-	-	S	ko:K06432	-	ko00000	Belongs to the SspO family
MDKIOEFL_02816	5.65e-27	sspP	-	-	S	ko:K06433	-	ko00000	Belongs to the SspP family
MDKIOEFL_02817	1.36e-83	cotM	-	-	O	ko:K06335	-	ko00000	Spore coat protein
MDKIOEFL_02818	2.79e-97	yneK	-	-	S	-	-	-	Protein of unknown function (DUF2621)
MDKIOEFL_02819	3.57e-98	yneJ	-	-	O	-	-	-	COG4846 Membrane protein involved in cytochrome C biogenesis
MDKIOEFL_02820	2.12e-77	ccdB	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
MDKIOEFL_02821	1.18e-164	ccdA	-	-	O	ko:K06196	-	ko00000,ko02000	cytochrome c biogenesis protein
MDKIOEFL_02822	4.59e-21	ynzD	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
MDKIOEFL_02823	4.36e-39	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
MDKIOEFL_02824	3.09e-106	yneE	-	-	S	-	-	-	Sporulation inhibitor of replication protein sirA
MDKIOEFL_02825	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MDKIOEFL_02826	1.15e-43	ynzC	-	-	S	-	-	-	UPF0291 protein
MDKIOEFL_02827	3.97e-145	yneB	-	-	L	-	-	-	resolvase
MDKIOEFL_02828	3.46e-64	yneA	-	-	D	-	-	-	Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
MDKIOEFL_02829	7.22e-142	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MDKIOEFL_02830	3.01e-102	fosB	-	-	H	ko:K11210,ko:K21252	-	ko00000,ko01000,ko01504	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
MDKIOEFL_02831	1.32e-96	yndM	-	-	S	-	-	-	Protein of unknown function (DUF2512)
MDKIOEFL_02832	6.31e-173	yndL	-	-	S	-	-	-	Replication protein
MDKIOEFL_02834	0.0	yndJ	-	-	S	-	-	-	YndJ-like protein
MDKIOEFL_02835	1.41e-148	-	-	-	S	-	-	-	Domain of unknown function (DUF4166)
MDKIOEFL_02836	1.7e-194	yndG	-	-	S	-	-	-	DoxX-like family
MDKIOEFL_02837	1.26e-285	-	-	-	S	ko:K06293,ko:K06312	-	ko00000	Spore germination protein
MDKIOEFL_02838	3.94e-250	yndE7	-	-	U	ko:K06311	-	ko00000,ko02000	Spore germination
MDKIOEFL_02839	0.0	yndD1	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
MDKIOEFL_02842	1.81e-103	yndB	-	-	S	-	-	-	Activator of Hsp90 ATPase homolog 1-like protein
MDKIOEFL_02843	1.04e-94	-	-	-	-	-	-	-	-
MDKIOEFL_02844	2.37e-34	tatA	-	-	U	ko:K03116,ko:K03117,ko:K03646	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02000,ko02044	protein secretion
MDKIOEFL_02847	5.34e-166	-	-	-	S	-	-	-	Domain of unknown function, YrpD
MDKIOEFL_02849	8.27e-40	-	-	-	-	-	-	-	-
MDKIOEFL_02850	3.21e-209	-	-	-	S	-	-	-	Thymidylate synthase
MDKIOEFL_02853	4.27e-102	yncF	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Deoxyuridine 5'-triphosphate
MDKIOEFL_02854	9.48e-108	-	-	-	S	-	-	-	Protein of unknown function (DUF2691)
MDKIOEFL_02856	2.51e-280	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MDKIOEFL_02857	0.0	-	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MDKIOEFL_02858	7.18e-145	yokF	3.1.31.1	-	L	ko:K01174	-	ko00000,ko01000	RNA catabolic process
MDKIOEFL_02859	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	xylulose kinase
MDKIOEFL_02860	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
MDKIOEFL_02861	1.44e-274	xylR	-	-	GK	-	-	-	ROK family
MDKIOEFL_02862	0.0	xynB	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
MDKIOEFL_02863	0.0	xynP	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
MDKIOEFL_02864	1.28e-102	-	-	-	E	-	-	-	phosphoribosylanthranilate isomerase activity
MDKIOEFL_02866	2.36e-53	ynaF	-	-	-	-	-	-	-
MDKIOEFL_02867	1.04e-145	-	-	-	S	-	-	-	Domain of unknown function (DUF3885)
MDKIOEFL_02868	9.72e-31	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
MDKIOEFL_02869	2.38e-11	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
MDKIOEFL_02870	2.62e-92	-	-	-	S	-	-	-	CAAX protease self-immunity
MDKIOEFL_02871	6.31e-121	ynaD	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
MDKIOEFL_02872	7.38e-273	-	-	-	H	-	-	-	N-terminal domain of galactosyltransferase
MDKIOEFL_02873	6.78e-245	-	-	-	M	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
MDKIOEFL_02874	1.66e-155	-	-	-	H	-	-	-	Methionine biosynthesis protein MetW
MDKIOEFL_02875	4.06e-119	-	-	-	M	-	-	-	Glycosyltransferase like family
MDKIOEFL_02876	3e-67	-	-	-	Q	-	-	-	Collagen triple helix repeat (20 copies)
MDKIOEFL_02879	4.02e-201	ydhU	-	-	P	ko:K07217	-	ko00000	Catalase
MDKIOEFL_02880	2.64e-268	ydhT1	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 26 family
MDKIOEFL_02881	1.64e-236	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
MDKIOEFL_02882	1.65e-212	gmuE	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	COG1940 Transcriptional regulator sugar kinase
MDKIOEFL_02883	7.75e-171	ydhQ	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
MDKIOEFL_02884	0.0	ydhP	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MDKIOEFL_02885	2.27e-305	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDKIOEFL_02886	3.39e-67	ydhN3	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MDKIOEFL_02887	1.88e-63	ydhM	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MDKIOEFL_02888	1.27e-254	ydhL	-	-	EGP	ko:K18567	-	ko00000,ko02000	COG2814 Arabinose efflux permease
MDKIOEFL_02889	4.3e-125	ydhK	-	-	M	-	-	-	Protein of unknown function (DUF1541)
MDKIOEFL_02890	7.41e-229	ydhJ	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
MDKIOEFL_02891	6.96e-41	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MDKIOEFL_02892	1.21e-82	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
MDKIOEFL_02893	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
MDKIOEFL_02894	5.89e-145	-	-	-	-	-	-	-	-
MDKIOEFL_02895	1.18e-274	ydhE	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MDKIOEFL_02896	1.53e-285	ydhD	-	-	M	-	-	-	Glycosyl hydrolase
MDKIOEFL_02897	6.31e-150	ydhC	-	-	K	-	-	-	FCD
MDKIOEFL_02898	1.39e-152	ydhB	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MDKIOEFL_02899	3.68e-261	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
MDKIOEFL_02901	6.42e-57	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
MDKIOEFL_02902	7.48e-124	-	-	-	E	-	-	-	branched-chain amino acid
MDKIOEFL_02903	1.42e-120	puuR1	-	-	K	-	-	-	Cupin domain
MDKIOEFL_02904	1.28e-87	-	-	-	K	-	-	-	Winged helix DNA-binding domain
MDKIOEFL_02905	7.5e-146	ydgI	-	-	C	-	-	-	nitroreductase
MDKIOEFL_02906	1.34e-155	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
MDKIOEFL_02907	5.13e-97	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MDKIOEFL_02908	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	drug exporters of the RND superfamily
MDKIOEFL_02909	8.12e-104	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MDKIOEFL_02910	3.44e-117	-	-	-	S	-	-	-	DinB family
MDKIOEFL_02911	0.0	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
MDKIOEFL_02912	0.0	expZ	-	-	S	ko:K18231	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ABC transporter
MDKIOEFL_02913	4.66e-110	yycN	-	-	K	-	-	-	Acetyltransferase
MDKIOEFL_02914	2.35e-69	-	-	-	S	-	-	-	DoxX-like family
MDKIOEFL_02915	2.85e-126	ydgC	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MDKIOEFL_02916	8.97e-47	ydgB	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
MDKIOEFL_02917	1.53e-47	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
MDKIOEFL_02918	1.81e-89	cotP	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
MDKIOEFL_02919	1.6e-138	ydfS	-	-	S	-	-	-	Protein of unknown function (DUF421)
MDKIOEFL_02920	8.71e-104	ydfR	-	-	S	-	-	-	Protein of unknown function (DUF421)
MDKIOEFL_02922	1.59e-40	-	-	-	-	-	-	-	-
MDKIOEFL_02923	2.4e-21	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
MDKIOEFL_02924	3.11e-73	ydfQ	-	-	CO	-	-	-	Thioredoxin
MDKIOEFL_02925	8.02e-84	ydfP	-	-	S	ko:K15977	-	ko00000	DoxX
MDKIOEFL_02926	1.11e-237	ydfO	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
MDKIOEFL_02927	8.74e-139	ydfN	-	-	C	ko:K15976	-	ko00000,ko01000	nitroreductase
MDKIOEFL_02928	5.22e-199	ydfM	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MDKIOEFL_02929	8.33e-187	-	-	-	K	-	-	-	Bacterial transcription activator, effector binding domain
MDKIOEFL_02930	2.27e-150	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
MDKIOEFL_02931	0.0	ydfJ	-	-	S	ko:K06994,ko:K11625	ko02020,map02020	ko00000,ko00001	drug exporters of the RND superfamily
MDKIOEFL_02932	1.33e-141	ydfI	-	-	K	ko:K11624	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MDKIOEFL_02933	1.31e-249	ydfH	2.7.13.3	-	T	ko:K11623	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MDKIOEFL_02935	3.92e-104	-	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MDKIOEFL_02936	6.11e-158	ydfF	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
MDKIOEFL_02937	4.04e-149	ydfE	-	-	S	-	-	-	Flavin reductase like domain
MDKIOEFL_02938	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MDKIOEFL_02939	2.68e-188	-	-	-	EG	-	-	-	EamA-like transporter family
MDKIOEFL_02940	9.3e-159	-	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
MDKIOEFL_02941	3.09e-278	-	-	-	T	-	-	-	GHKL domain
MDKIOEFL_02942	1.34e-198	-	-	-	-	-	-	-	-
MDKIOEFL_02943	8.39e-157	nodB1	-	-	G	-	-	-	deacetylase
MDKIOEFL_02944	4.58e-189	-	-	-	K	-	-	-	Transcriptional regulator
MDKIOEFL_02945	1.28e-183	-	-	-	J	-	-	-	GNAT acetyltransferase
MDKIOEFL_02946	1.75e-294	arsB	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MDKIOEFL_02947	3e-75	arsR	-	-	K	ko:K03892,ko:K22043	-	ko00000,ko03000	transcriptional
MDKIOEFL_02948	6.56e-194	ydeO	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MDKIOEFL_02949	3.03e-74	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
MDKIOEFL_02950	2.81e-134	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
MDKIOEFL_02951	4.3e-96	ydeM1	-	-	I	-	-	-	N-terminal half of MaoC dehydratase
MDKIOEFL_02952	0.0	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MDKIOEFL_02953	1.49e-193	ydeK	-	-	EG	-	-	-	-transporter
MDKIOEFL_02954	1.96e-146	-	-	-	-	-	-	-	-
MDKIOEFL_02955	4.53e-132	ydeI	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
MDKIOEFL_02956	7.89e-71	ydeH	-	-	-	-	-	-	-
MDKIOEFL_02957	6.57e-278	ydeG	-	-	EGP	-	-	-	Major facilitator superfamily
MDKIOEFL_02958	0.0	-	-	-	K	-	-	-	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MDKIOEFL_02959	3.34e-212	ydeE	-	-	K	ko:K13653	-	ko00000,ko03000	AraC family transcriptional regulator
MDKIOEFL_02960	2.37e-222	ydeD	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MDKIOEFL_02961	5.13e-208	-	-	-	K	-	-	-	AraC-like ligand binding domain
MDKIOEFL_02962	6.72e-41	ydzE	-	-	EG	-	-	-	spore germination
MDKIOEFL_02963	3.57e-103	ydeB	-	-	K	ko:K07736	-	ko00000,ko03000	Transcription factor
MDKIOEFL_02964	4.22e-41	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
MDKIOEFL_02965	4.75e-245	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
MDKIOEFL_02966	2.89e-84	-	-	-	L	-	-	-	HNH nucleases
MDKIOEFL_02967	9.58e-288	ydeG3	-	-	EGP	-	-	-	Major Facilitator Superfamily
MDKIOEFL_02968	2.71e-184	yddR	-	-	S	-	-	-	Zn-dependent hydrolases of the beta-lactamase fold
MDKIOEFL_02969	1.62e-128	yddQ	-	-	Q	-	-	-	Isochorismatase family
MDKIOEFL_02970	1.26e-101	lrpB	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	transcriptional
MDKIOEFL_02971	8.15e-94	lrpA	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	transcriptional
MDKIOEFL_02972	9.91e-241	-	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MDKIOEFL_02980	3.74e-108	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
MDKIOEFL_02981	0.0	tex	-	-	K	ko:K06959	-	ko00000	COG2183 Transcriptional accessory protein
MDKIOEFL_02982	1.79e-100	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MDKIOEFL_02983	3.11e-105	ydcG	-	-	S	-	-	-	EVE domain
MDKIOEFL_02986	2.17e-140	rsbX	3.1.3.3	-	KT	ko:K05518	-	ko00000,ko01000,ko03021	Sigma factor PP2C-like phosphatases
MDKIOEFL_02987	1.55e-178	sigB	-	-	K	ko:K03090	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MDKIOEFL_02988	8.3e-110	rsbW	2.7.11.1	-	F	ko:K04757	-	ko00000,ko01000,ko01001,ko03021	Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
MDKIOEFL_02989	3.98e-70	rsbV	-	-	T	ko:K04749	-	ko00000,ko03021	Belongs to the anti-sigma-factor antagonist family
MDKIOEFL_02990	1.08e-242	rsbU	3.1.3.3	-	KT	ko:K07315	-	ko00000,ko01000,ko03021	phosphatase
MDKIOEFL_02991	2.45e-89	rsbT	2.7.11.1	-	T	ko:K17752	-	ko00000,ko01000,ko01001,ko03021	COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
MDKIOEFL_02992	1.8e-74	rsbS	-	-	T	ko:K17762	-	ko00000,ko03021	antagonist
MDKIOEFL_02993	8.58e-184	rsbR	-	-	T	ko:K17763	-	ko00000,ko03021	Positive regulator of sigma-B
MDKIOEFL_02994	4.34e-75	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
MDKIOEFL_02995	9.49e-57	ndoAI	-	-	K	ko:K07723	-	ko00000,ko02048,ko03000	transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
MDKIOEFL_02996	4.17e-281	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MDKIOEFL_02997	1.9e-233	ydcC	-	-	M	-	-	-	COG2834 Outer membrane lipoprotein-sorting protein
MDKIOEFL_02998	1.6e-77	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MDKIOEFL_02999	2.53e-139	ydcA	-	-	S	-	-	-	membrane protein (homolog of Drosophila rhomboid)
MDKIOEFL_03000	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Membrane
MDKIOEFL_03001	2.12e-107	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
MDKIOEFL_03002	0.0	cshA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MDKIOEFL_03003	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MDKIOEFL_03004	4.18e-256	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
MDKIOEFL_03005	4.19e-75	ydbP	-	-	CO	-	-	-	Thioredoxin
MDKIOEFL_03006	2.72e-202	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MDKIOEFL_03007	2.1e-11	-	-	-	S	-	-	-	Fur-regulated basic protein A
MDKIOEFL_03008	1.49e-26	-	-	-	S	-	-	-	Fur-regulated basic protein B
MDKIOEFL_03009	6.12e-279	ydbM	-	-	I	-	-	-	acyl-CoA dehydrogenase
MDKIOEFL_03010	9.32e-70	ydbL	-	-	-	-	-	-	-
MDKIOEFL_03011	2.99e-159	ydbK	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MDKIOEFL_03012	4.59e-219	ydbJ	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MDKIOEFL_03013	1.32e-230	ydbI	-	-	S	-	-	-	AI-2E family transporter
MDKIOEFL_03014	3.64e-289	dctA	-	-	U	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MDKIOEFL_03015	2.79e-154	dctR	-	-	T	ko:K02475,ko:K11692	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
MDKIOEFL_03016	0.0	dctS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
MDKIOEFL_03017	3.66e-253	dctB	-	-	G	-	-	-	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
MDKIOEFL_03018	1.35e-198	ydbD	-	-	P	ko:K07217	-	ko00000	Catalase
MDKIOEFL_03019	5.41e-84	ydbC	-	-	S	-	-	-	Domain of unknown function (DUF4937
MDKIOEFL_03020	7.58e-79	ydbB	-	-	G	-	-	-	Cupin domain
MDKIOEFL_03021	3.3e-10	gsiB	-	-	S	ko:K06884	-	ko00000	general stress protein
MDKIOEFL_03022	2.49e-189	ydbA	-	-	P	-	-	-	EcsC protein family
MDKIOEFL_03023	2.25e-100	ydaT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
MDKIOEFL_03024	1.67e-42	ydaS	-	-	S	-	-	-	membrane
MDKIOEFL_03025	3.9e-286	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
MDKIOEFL_03026	6.14e-53	-	-	-	-	-	-	-	-
MDKIOEFL_03027	0.0	ydaP	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
MDKIOEFL_03028	5.12e-101	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
MDKIOEFL_03029	0.0	ydaO	-	-	E	-	-	-	amino acid
MDKIOEFL_03030	0.0	ydaN	-	-	S	-	-	-	Bacterial cellulose synthase subunit
MDKIOEFL_03031	1.12e-303	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
MDKIOEFL_03032	0.0	ydaL	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2334)
MDKIOEFL_03033	4.28e-191	ydaK	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
MDKIOEFL_03034	8.13e-263	ydaJ	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
MDKIOEFL_03035	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MDKIOEFL_03036	3.95e-98	lrpC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
MDKIOEFL_03037	3.12e-61	ydzA	-	-	EGP	-	-	-	Domain of unknown function (DUF3817)
MDKIOEFL_03038	1.31e-178	amj	-	-	U	-	-	-	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
MDKIOEFL_03039	5.24e-101	ydaG	-	-	S	-	-	-	general stress protein
MDKIOEFL_03040	1.1e-132	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MDKIOEFL_03041	2.36e-126	ydaE	5.3.1.15	-	S	ko:K09988	ko00040,map00040	ko00000,ko00001,ko01000	Cupin 2, conserved barrel domain protein
MDKIOEFL_03042	1.07e-206	ydaD	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MDKIOEFL_03043	1e-127	ydaC	-	-	Q	-	-	-	Methyltransferase domain
MDKIOEFL_03044	0.0	ydaB	-	-	IQ	-	-	-	acyl-CoA ligase
MDKIOEFL_03045	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	transcriptional regulator, MtlR
MDKIOEFL_03046	1.49e-220	ycsN	-	-	S	-	-	-	Oxidoreductase
MDKIOEFL_03047	0.0	pbpC	3.4.16.4	-	M	ko:K02545,ko:K21467	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	Penicillin-binding Protein
MDKIOEFL_03048	1.81e-64	yczJ	-	-	S	-	-	-	biosynthesis
MDKIOEFL_03050	4.5e-149	ycsK	-	-	E	-	-	-	anatomical structure formation involved in morphogenesis
MDKIOEFL_03051	1.55e-170	kipR	-	-	K	-	-	-	Transcriptional regulator
MDKIOEFL_03052	3.31e-237	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
MDKIOEFL_03053	2.3e-169	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
MDKIOEFL_03054	6.72e-188	ycsI	-	-	S	-	-	-	Belongs to the D-glutamate cyclase family
MDKIOEFL_03055	2.78e-273	ycsG	-	-	P	-	-	-	COG1914 Mn2 and Fe2 transporters of the NRAMP family
MDKIOEFL_03056	3.14e-180	ycsF	-	-	S	ko:K07160	-	ko00000	Belongs to the UPF0271 (lamB) family
MDKIOEFL_03057	1.9e-177	ycsE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
MDKIOEFL_03059	9.34e-88	ycsD	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
MDKIOEFL_03060	3.32e-141	-	-	-	Q	-	-	-	COG0412 Dienelactone hydrolase and related enzymes
MDKIOEFL_03061	5.1e-96	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MDKIOEFL_03063	1.01e-256	ycsA	1.1.1.83, 1.1.1.93, 4.1.1.73	-	CE	ko:K07246	ko00630,ko00650,map00630,map00650	ko00000,ko00001,ko01000	Tartrate dehydrogenase
MDKIOEFL_03064	1.53e-268	mtlD	1.1.1.17	-	G	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	COG0246 Mannitol-1-phosphate altronate dehydrogenases
MDKIOEFL_03065	8.3e-95	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
MDKIOEFL_03066	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG2213 Phosphotransferase system, mannitol-specific IIBC component
MDKIOEFL_03067	5.46e-74	-	-	-	-	-	-	-	-
MDKIOEFL_03068	4.09e-136	ycnK	-	-	K	ko:K21601	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
MDKIOEFL_03069	0.0	ycnJ	-	-	P	ko:K14166	-	ko00000,ko02000	protein, homolog of Cu resistance protein CopC
MDKIOEFL_03070	3.99e-134	ycnI	-	-	S	-	-	-	protein conserved in bacteria
MDKIOEFL_03071	5.9e-187	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MDKIOEFL_03072	1.67e-190	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	Glucose uptake
MDKIOEFL_03073	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MDKIOEFL_03074	9.35e-311	gabT	2.6.1.19, 2.6.1.22	-	E	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MDKIOEFL_03075	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MDKIOEFL_03076	6.51e-69	yczG	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
MDKIOEFL_03077	1.68e-60	ycnE	-	-	S	-	-	-	Monooxygenase
MDKIOEFL_03078	8.65e-174	-	1.5.1.39	-	C	ko:K10678,ko:K19286	ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120	ko00000,ko00001,ko01000	Oxidoreductase
MDKIOEFL_03079	2.91e-198	ycnC	-	-	K	-	-	-	Transcriptional regulator
MDKIOEFL_03080	0.0	ycnB	-	-	EGP	-	-	-	the major facilitator superfamily
MDKIOEFL_03081	6.67e-212	yclQ	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4607 ABC-type enterochelin transport system, periplasmic component
MDKIOEFL_03082	2.29e-175	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MDKIOEFL_03083	9.06e-209	yclO	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MDKIOEFL_03084	1.09e-205	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MDKIOEFL_03085	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
MDKIOEFL_03086	7.93e-06	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
MDKIOEFL_03087	1.58e-05	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
MDKIOEFL_03089	2.18e-97	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
MDKIOEFL_03090	0.0	yclK	-	-	T	-	-	-	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
MDKIOEFL_03091	6.39e-165	yclJ	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MDKIOEFL_03092	6.2e-277	yclI	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease) YclI
MDKIOEFL_03093	1.18e-155	yclH	-	-	P	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
MDKIOEFL_03094	1.93e-246	gerKB	-	-	F	ko:K06296	-	ko00000,ko02000	Spore germination protein
MDKIOEFL_03095	3.21e-285	gerKC	-	-	S	ko:K06297	-	ko00000	spore germination
MDKIOEFL_03096	0.0	gerKA	-	-	EG	ko:K06295,ko:K06307	-	ko00000	Spore germination protein
MDKIOEFL_03098	0.0	yclG	-	-	M	-	-	-	Pectate lyase superfamily protein
MDKIOEFL_03099	0.0	dtpT	-	-	E	ko:K03305	-	ko00000	amino acid peptide transporter
MDKIOEFL_03100	4.71e-203	yclE	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Alpha beta hydrolase
MDKIOEFL_03101	1.45e-107	yclD	-	-	-	-	-	-	-
MDKIOEFL_03102	1.15e-51	-	4.1.1.61	-	S	ko:K21759	ko00627,ko01120,ko01220,map00627,map01120,map01220	ko00000,ko00001,ko01000	response to toxic substance
MDKIOEFL_03103	0.0	yclC	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
MDKIOEFL_03104	2.24e-140	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
MDKIOEFL_03105	5.32e-209	yclA	-	-	K	ko:K21755	-	ko00000,ko03000	LysR substrate binding domain
MDKIOEFL_03106	3.54e-187	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
MDKIOEFL_03107	4.6e-157	tcyB	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
MDKIOEFL_03108	7.11e-172	tcyC	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
MDKIOEFL_03109	8.71e-148	yczE	-	-	S	ko:K07149	-	ko00000	membrane
MDKIOEFL_03110	2.02e-146	sfp	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
MDKIOEFL_03111	0.0	ycxD	-	-	K	-	-	-	GntR family transcriptional regulator
MDKIOEFL_03112	2.68e-204	ycxC	-	-	EG	-	-	-	EamA-like transporter family
MDKIOEFL_03113	3.35e-119	-	-	-	S	-	-	-	YcxB-like protein
MDKIOEFL_03114	3.32e-283	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MDKIOEFL_03115	1.63e-179	srfAD	-	-	Q	ko:K15657	ko02024,map02024	ko00000,ko00001,ko01008	thioesterase
MDKIOEFL_03116	0.0	srfAC	-	-	Q	ko:K15656,ko:K16121	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	COG1020 Non-ribosomal peptide synthetase modules and related proteins
MDKIOEFL_03117	0.0	srfAB	-	-	Q	ko:K15654,ko:K15655,ko:K16120	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDKIOEFL_03118	0.0	srfAA	-	-	Q	ko:K15654,ko:K15655,ko:K16119	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDKIOEFL_03119	6.05e-86	hxlR	-	-	K	-	-	-	transcriptional
MDKIOEFL_03120	3.97e-137	hxlA	4.1.2.43	-	G	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	3-hexulose-6-phosphate synthase
MDKIOEFL_03121	5.38e-125	hxlB	5.3.1.27	-	G	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	SIS domain
MDKIOEFL_03122	5.32e-268	tlpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MDKIOEFL_03123	7.94e-100	nucA	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
MDKIOEFL_03124	5.81e-92	nin	-	-	S	-	-	-	Competence protein J (ComJ)
MDKIOEFL_03125	0.0	yckE	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MDKIOEFL_03126	1.01e-68	yckD	-	-	S	-	-	-	Protein of unknown function (DUF2680)
MDKIOEFL_03127	1.64e-98	yckC	-	-	S	-	-	-	membrane
MDKIOEFL_03129	3.09e-186	yckB	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
MDKIOEFL_03130	2.99e-149	yckA	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
MDKIOEFL_03131	9.24e-289	yciC	-	-	S	-	-	-	GTPases (G3E family)
MDKIOEFL_03132	7.04e-139	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
MDKIOEFL_03133	1.67e-219	folE2	3.5.4.16	-	S	ko:K09007	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Converts GTP to 7,8-dihydroneopterin triphosphate
MDKIOEFL_03134	3.18e-282	nasA	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
MDKIOEFL_03135	0.0	nasB	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Assimilatory nitrate reductase (electron transfer subunit)
MDKIOEFL_03136	0.0	nasC	-	-	C	ko:K00372	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MDKIOEFL_03137	0.0	nasD	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MDKIOEFL_03138	1.2e-74	nasE	1.7.1.15	-	P	ko:K00363	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Nitrite reductase
MDKIOEFL_03139	0.0	nasF	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
MDKIOEFL_03140	5.3e-239	ycgT	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
MDKIOEFL_03141	2.95e-203	ycgS	-	-	I	-	-	-	alpha/beta hydrolase fold
MDKIOEFL_03142	9.14e-187	ycgR	-	-	S	ko:K07089	-	ko00000	permeases
MDKIOEFL_03143	2.88e-190	ycgQ	-	-	S	ko:K08986	-	ko00000	membrane
MDKIOEFL_03144	3.92e-288	ycgP	-	-	QT	-	-	-	COG2508 Regulator of polyketide synthase expression
MDKIOEFL_03145	0.0	putP	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MDKIOEFL_03146	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
MDKIOEFL_03147	3.63e-218	ycgM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
MDKIOEFL_03148	9.06e-186	ycgL	-	-	S	ko:K07074	-	ko00000	Predicted nucleotidyltransferase
MDKIOEFL_03149	3.84e-232	cah	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	Acetyl xylan esterase (AXE1)
MDKIOEFL_03150	1.33e-226	ycgK	-	-	K	ko:K04761	ko02026,map02026	ko00000,ko00001,ko03000	LysR substrate binding domain
MDKIOEFL_03151	4.15e-183	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
MDKIOEFL_03152	4.28e-136	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MDKIOEFL_03153	2.09e-137	tmrB	-	-	S	-	-	-	AAA domain
MDKIOEFL_03154	1.83e-191	nadE	6.3.1.5	-	H	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MDKIOEFL_03155	7.6e-145	ycgI	-	-	S	ko:K09967	-	ko00000	Domain of unknown function (DUF1989)
MDKIOEFL_03156	0.0	ycgH	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
MDKIOEFL_03157	6.94e-193	yqcI	-	-	S	ko:K09190	-	ko00000	YqcI/YcgG family
MDKIOEFL_03158	6.42e-147	ycgF	-	-	E	-	-	-	Lysine exporter protein LysE YggA
MDKIOEFL_03159	2.14e-100	ycgE	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MDKIOEFL_03160	0.0	mdr	-	-	EGP	-	-	-	the major facilitator superfamily
MDKIOEFL_03161	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
MDKIOEFL_03162	2.93e-233	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
MDKIOEFL_03163	0.0	amyE	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	alpha-amylase
MDKIOEFL_03164	3.86e-105	ycgB	-	-	-	-	-	-	-
MDKIOEFL_03165	0.0	ycgA	-	-	S	-	-	-	Membrane
MDKIOEFL_03166	2.4e-277	amhX	-	-	S	ko:K14665	-	ko00000,ko01000,ko01002	amidohydrolase
MDKIOEFL_03167	2.01e-210	opuAC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
MDKIOEFL_03168	2.1e-186	opuAB	-	-	P	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
MDKIOEFL_03169	8.99e-293	opuAA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
MDKIOEFL_03170	4.82e-61	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
MDKIOEFL_03171	0.0	-	-	-	S	ko:K19175	-	ko00000,ko02048	Domain of unknown function DUF87
MDKIOEFL_03172	2.19e-86	-	-	-	-	ko:K19174	-	ko00000,ko02048	-
MDKIOEFL_03173	6.83e-132	-	-	-	V	ko:K19173	-	ko00000,ko02048	Type I site-specific restriction-modification system, R (Restriction) subunit and related
MDKIOEFL_03174	2.86e-193	-	-	-	S	ko:K19169	-	ko00000,ko02048	DNA-sulfur modification-associated
MDKIOEFL_03175	8.5e-272	-	-	-	EH	ko:K19170	-	ko00000,ko02048	COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase and related enzymes
MDKIOEFL_03176	3.14e-187	-	-	-	EL	ko:K19171	-	ko00000,ko02048	AAA domain
MDKIOEFL_03177	1.9e-41	-	-	-	S	-	-	-	DNA sulphur modification protein DndE
MDKIOEFL_03178	8.04e-181	-	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class-V
MDKIOEFL_03179	6.41e-251	-	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
MDKIOEFL_03180	1.56e-277	yceI	-	-	P	ko:K08369	-	ko00000,ko02000	Uncharacterised MFS-type transporter YbfB
MDKIOEFL_03181	2.96e-245	yceH	-	-	P	-	-	-	Belongs to the TelA family
MDKIOEFL_03182	0.0	yceG	-	-	S	-	-	-	Putative component of 'biosynthetic module'
MDKIOEFL_03183	1.18e-175	yceF	-	-	P	ko:K05794	-	ko00000	Protein of unknown function (DUF475)
MDKIOEFL_03184	2.87e-137	yceE	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
MDKIOEFL_03185	8.9e-137	yceD	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
MDKIOEFL_03186	3.75e-141	yceC	3.5.4.33	-	T	ko:K11991	-	ko00000,ko01000,ko03016	proteins involved in stress response, homologs of TerZ and
MDKIOEFL_03187	1.4e-236	yceB	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MDKIOEFL_03188	4.63e-173	adcB	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MDKIOEFL_03189	2.32e-169	adcC	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MDKIOEFL_03190	1.95e-221	adcA	-	-	P	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
MDKIOEFL_03191	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
MDKIOEFL_03192	3.26e-178	-	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
MDKIOEFL_03193	3.33e-247	rapJ	-	-	S	ko:K06368	-	ko00000,ko01000	Response regulator aspartate phosphatase
MDKIOEFL_03194	4.4e-122	-	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
MDKIOEFL_03195	0.0	ycdC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MDKIOEFL_03196	0.0	ycdB	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MDKIOEFL_03197	1.35e-241	ycdA	-	-	S	-	-	-	Domain of unknown function (DUF5105)
MDKIOEFL_03198	1.37e-221	yccK	-	-	C	-	-	-	Aldo keto reductase
MDKIOEFL_03199	2.56e-253	-	-	-	CP	ko:K09696	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
MDKIOEFL_03200	8.97e-170	natA	3.6.3.7	-	CP	ko:K01990,ko:K09697	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
MDKIOEFL_03201	6.58e-161	natR	-	-	T	ko:K02477,ko:K11641	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
MDKIOEFL_03202	1.42e-202	natK	2.7.13.3	-	T	ko:K11640	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
MDKIOEFL_03203	2.9e-254	yccF	-	-	K	ko:K07039	-	ko00000	SEC-C motif
MDKIOEFL_03204	1.33e-72	-	-	-	S	-	-	-	RDD family
MDKIOEFL_03205	1.63e-146	-	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MDKIOEFL_03206	1.69e-257	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
MDKIOEFL_03207	2.67e-131	lmrA	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
MDKIOEFL_03208	1.24e-302	lmrB	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	the major facilitator superfamily
MDKIOEFL_03209	2.52e-261	ycbU	-	-	E	-	-	-	Selenocysteine lyase
MDKIOEFL_03210	1.4e-153	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MDKIOEFL_03211	3.09e-159	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MDKIOEFL_03212	3.12e-38	tatAD	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MDKIOEFL_03213	0.0	phoD	3.1.3.1	-	P	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG3540 Phosphodiesterase alkaline phosphatase D
MDKIOEFL_03214	2.7e-174	ycbR	-	-	T	-	-	-	vWA found in TerF C terminus
MDKIOEFL_03215	5.22e-102	cwlJ	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell wall
MDKIOEFL_03216	2.21e-76	ycbP	-	-	S	-	-	-	Protein of unknown function (DUF2512)
MDKIOEFL_03217	3.34e-147	-	-	-	S	-	-	-	ABC-2 family transporter protein
MDKIOEFL_03218	1.86e-213	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MDKIOEFL_03219	2.26e-216	ycbM	-	-	T	-	-	-	Histidine kinase
MDKIOEFL_03220	1.84e-160	ycbL	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MDKIOEFL_03221	1.41e-215	eamA1	-	-	EG	-	-	-	spore germination
MDKIOEFL_03222	8.73e-33	rtpA	-	-	K	-	-	-	Tryptophan RNA-binding attenuator protein inhibitory protein
MDKIOEFL_03223	6.07e-223	ycbJ	-	-	S	ko:K06979	-	br01600,ko00000,ko00002,ko01504	Macrolide 2'-phosphotransferase
MDKIOEFL_03224	0.0	garD	4.2.1.42, 4.2.1.7	-	G	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
MDKIOEFL_03225	7.68e-160	ycbG	-	-	K	ko:K05799	-	ko00000,ko03000	FCD
MDKIOEFL_03226	0.0	gudD	4.2.1.40	-	M	ko:K01706	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
MDKIOEFL_03227	0.0	gudP	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MDKIOEFL_03228	0.0	ycbD	-	-	C	ko:K22187	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MDKIOEFL_03229	4.1e-222	ycbC	4.2.1.41	-	EM	ko:K01707	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	5-dehydro-4-deoxyglucarate dehydratase activity
MDKIOEFL_03230	4.94e-217	glnL	-	-	T	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Regulator
MDKIOEFL_03231	2.05e-293	glnJ	2.7.13.3	-	T	ko:K07717	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MDKIOEFL_03232	3.06e-238	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
MDKIOEFL_03233	0.0	agcS	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
MDKIOEFL_03234	1.29e-233	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine
MDKIOEFL_03235	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MDKIOEFL_03236	1.34e-258	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
MDKIOEFL_03238	2.91e-165	-	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
MDKIOEFL_03239	5e-173	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MDKIOEFL_03240	0.0	ptsG	2.7.1.199	-	G	ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MDKIOEFL_03241	6.04e-273	gltP	-	-	C	ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MDKIOEFL_03242	1.16e-244	ybfQ	-	-	S	ko:K07146	-	ko00000	Belongs to the UPF0176 family
MDKIOEFL_03243	9.32e-317	-	-	-	S	ko:K06880	-	ko00000,ko01000,ko01504	Erythromycin esterase
MDKIOEFL_03244	1.58e-59	ybfN	-	-	-	-	-	-	-
MDKIOEFL_03245	2.06e-188	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
MDKIOEFL_03246	7.07e-112	ybfM	-	-	S	-	-	-	SNARE associated Golgi protein
MDKIOEFL_03247	1.15e-122	pssA	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MDKIOEFL_03248	2.17e-211	-	-	-	S	-	-	-	Alpha/beta hydrolase family
MDKIOEFL_03250	5.04e-230	mpr	-	-	M	-	-	-	Belongs to the peptidase S1B family
MDKIOEFL_03251	4.41e-269	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MDKIOEFL_03252	1.17e-89	-	-	-	M	-	-	-	nucleic acid phosphodiester bond hydrolysis
MDKIOEFL_03253	3.82e-185	draG	-	-	O	-	-	-	ADP-ribosylglycohydrolase
MDKIOEFL_03254	7.08e-186	ybfI	-	-	K	-	-	-	AraC-like ligand binding domain
MDKIOEFL_03255	2.4e-204	ybfH	-	-	EG	-	-	-	EamA-like transporter family
MDKIOEFL_03256	0.0	ybfG	-	-	M	-	-	-	Domain of unknown function (DUF1906)
MDKIOEFL_03258	5.31e-284	ybfB	-	-	G	-	-	-	COG0477 Permeases of the major facilitator superfamily
MDKIOEFL_03259	1.22e-217	ybfA	-	-	K	-	-	-	FR47-like protein
MDKIOEFL_03260	1.02e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2651)
MDKIOEFL_03261	0.0	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	-transporter
MDKIOEFL_03262	1.3e-206	glpQ	3.1.3.1, 3.1.4.46	-	C	ko:K01113,ko:K01126	ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	glycerophosphoryl diester phosphodiesterase
MDKIOEFL_03263	0.0	ybeC	-	-	E	-	-	-	amino acid
MDKIOEFL_03264	1.11e-54	ybyB	-	-	-	-	-	-	-
MDKIOEFL_03265	3.8e-314	cypC	1.11.2.4	-	Q	ko:K15629	-	ko00000,ko00199,ko01000	Cytochrome P450
MDKIOEFL_03266	5.05e-191	ybxI	3.5.2.6	-	V	ko:K17838	ko01501,map01501	ko00000,ko00001,ko01000	beta-lactamase
MDKIOEFL_03267	6.92e-41	ybxH	-	-	S	-	-	-	Family of unknown function (DUF5370)
MDKIOEFL_03268	5.46e-51	csgA	-	-	S	-	-	-	Sigma-G-dependent sporulation-specific SASP protein
MDKIOEFL_03269	0.0	ybxG	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
MDKIOEFL_03270	8.6e-272	ybdO	-	-	S	-	-	-	Domain of unknown function (DUF4885)
MDKIOEFL_03271	4.28e-192	ybdN	-	-	-	-	-	-	-
MDKIOEFL_03272	3.4e-179	ybdM	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
MDKIOEFL_03274	4.61e-218	-	-	-	T	-	-	-	His Kinase A (phospho-acceptor) domain
MDKIOEFL_03275	9.8e-158	-	-	-	T	ko:K02483	-	ko00000,ko02022	Transcriptional regulatory protein, C terminal
MDKIOEFL_03276	4.47e-230	-	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MDKIOEFL_03277	3.35e-73	-	-	-	-	-	-	-	-
MDKIOEFL_03278	8.96e-256	ybcL	-	-	EGP	ko:K08164	-	ko00000,ko02000	COG2814 Arabinose efflux permease
MDKIOEFL_03279	9.45e-67	-	-	-	K	-	-	-	Helix-turn-helix domain
MDKIOEFL_03280	3.6e-80	ybcI	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
MDKIOEFL_03281	4.6e-63	-	-	-	-	-	-	-	-
MDKIOEFL_03283	4.01e-120	ybcF	-	-	P	-	-	-	carbonic anhydrase
MDKIOEFL_03284	0.0	ybcC	-	-	S	ko:K09822	-	ko00000	Belongs to the UPF0753 family
MDKIOEFL_03285	0.0	ndhF	1.6.5.3	-	CP	ko:K05577	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MDKIOEFL_03286	2.5e-125	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MDKIOEFL_03287	8.81e-153	adaA	-	-	K	ko:K13530	-	ko00000,ko01000,ko03000,ko03400	Transcriptional regulator
MDKIOEFL_03288	3.24e-221	alkA	3.2.2.21	-	L	ko:K01247,ko:K13529	ko03410,map03410	ko00000,ko00001,ko01000,ko03000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MDKIOEFL_03289	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MDKIOEFL_03290	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MDKIOEFL_03291	3.55e-291	ybbR	-	-	S	-	-	-	protein conserved in bacteria
MDKIOEFL_03292	5.43e-189	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MDKIOEFL_03293	1.3e-150	rsiW	-	-	K	-	-	-	Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
MDKIOEFL_03294	4.59e-127	sigW	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MDKIOEFL_03300	2.43e-100	ybbK	-	-	S	-	-	-	Protein of unknown function (DUF523)
MDKIOEFL_03301	5.2e-113	ybbJ	-	-	J	-	-	-	acetyltransferase
MDKIOEFL_03302	1.64e-210	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MDKIOEFL_03303	1.56e-193	ybbH	-	-	K	-	-	-	transcriptional
MDKIOEFL_03304	5.99e-303	ybbF	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MDKIOEFL_03305	0.0	ybbE	3.4.16.4	-	V	ko:K21469	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the UPF0214 family
MDKIOEFL_03306	0.0	ybbD	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 3 family
MDKIOEFL_03307	1.41e-303	ybbC	-	-	S	-	-	-	protein conserved in bacteria
MDKIOEFL_03308	0.0	ybbB	-	-	K	ko:K21701	-	ko00000,ko03000	COG2207 AraC-type DNA-binding domain-containing proteins
MDKIOEFL_03309	3.6e-216	feuA	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Iron-uptake system-binding protein
MDKIOEFL_03310	1.17e-225	feuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MDKIOEFL_03311	3.51e-228	feuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MDKIOEFL_03312	5.87e-177	ybbA	-	-	S	ko:K07017	-	ko00000	Putative esterase
MDKIOEFL_03313	4.71e-203	ybaS	-	-	S	-	-	-	Na -dependent transporter
MDKIOEFL_03315	0.0	ybaR	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
MDKIOEFL_03316	8.23e-215	ygxA	-	-	S	-	-	-	Nucleotidyltransferase-like
MDKIOEFL_03317	3.38e-73	ygzB	-	-	S	-	-	-	UPF0295 protein
MDKIOEFL_03318	2.37e-104	perR	-	-	P	ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
MDKIOEFL_03319	1.69e-112	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Peroxiredoxin
MDKIOEFL_03320	3.26e-312	gsaB	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
MDKIOEFL_03321	1.87e-238	ygaE	-	-	S	-	-	-	Membrane
MDKIOEFL_03322	0.0	ygaD	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
MDKIOEFL_03323	8.1e-136	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
MDKIOEFL_03324	8.19e-49	ygaB	-	-	S	-	-	-	YgaB-like protein
MDKIOEFL_03325	2.35e-14	sspE	-	-	S	ko:K06422	-	ko00000	Small, acid-soluble spore protein, gamma-type
MDKIOEFL_03326	3.13e-172	fabL	1.3.1.104	-	IQ	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MDKIOEFL_03327	1.73e-48	yfhS	-	-	-	-	-	-	-
MDKIOEFL_03328	7.55e-265	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific
MDKIOEFL_03329	2.07e-236	yfhP	-	-	S	ko:K07038	-	ko00000	membrane-bound metal-dependent
MDKIOEFL_03330	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
MDKIOEFL_03331	3.43e-236	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
MDKIOEFL_03332	6.53e-217	yfhM	3.8.1.5	-	S	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Alpha beta hydrolase
MDKIOEFL_03333	3.65e-65	yfhL	-	-	S	-	-	-	SdpI/YhfL protein family
MDKIOEFL_03334	1.11e-113	yfhK	-	-	T	-	-	-	Bacterial SH3 domain homologues
MDKIOEFL_03335	8.95e-60	yfhJ	-	-	S	-	-	-	WVELL protein
MDKIOEFL_03336	2.25e-27	sspK	-	-	S	ko:K06428	-	ko00000	reproduction
MDKIOEFL_03337	2.45e-268	yfhI	-	-	EGP	-	-	-	-transporter
MDKIOEFL_03339	4.58e-69	yfhH	-	-	S	-	-	-	Protein of unknown function (DUF1811)
MDKIOEFL_03340	5.39e-180	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
MDKIOEFL_03341	1.54e-219	yfhF	-	-	S	ko:K07071	-	ko00000	nucleoside-diphosphate sugar epimerase
MDKIOEFL_03343	8.86e-35	yfhD	-	-	S	-	-	-	YfhD-like protein
MDKIOEFL_03344	2.87e-138	yfhC	-	-	C	-	-	-	nitroreductase
MDKIOEFL_03345	1.21e-211	yfhB	-	-	S	-	-	-	PhzF family
MDKIOEFL_03346	7.36e-229	yfhA	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MDKIOEFL_03347	2.55e-224	yfiZ	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MDKIOEFL_03348	3.83e-231	yfiY	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MDKIOEFL_03349	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MDKIOEFL_03350	2.11e-103	yfiV	-	-	K	-	-	-	transcriptional
MDKIOEFL_03351	0.0	yfiU	-	-	EGP	-	-	-	the major facilitator superfamily
MDKIOEFL_03352	8.07e-128	yfiT	-	-	S	-	-	-	Belongs to the metal hydrolase YfiT family
MDKIOEFL_03353	7.67e-252	yfiQ	-	-	G	ko:K21462	-	ko00000	COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
MDKIOEFL_03354	7.87e-128	lip	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MDKIOEFL_03355	1.89e-128	padR	-	-	K	-	-	-	transcriptional
MDKIOEFL_03356	1.15e-260	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
MDKIOEFL_03357	1.2e-263	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
MDKIOEFL_03358	5.33e-215	drrA	-	-	V	ko:K01990,ko:K09695	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MDKIOEFL_03359	8.27e-144	yfiK	-	-	KT	ko:K02479	-	ko00000,ko02022	LuxR family transcriptional regulator
MDKIOEFL_03360	4.15e-240	baeS	-	-	T	-	-	-	Histidine kinase
MDKIOEFL_03361	2.85e-206	yfiE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
MDKIOEFL_03362	4.74e-83	yfiD3	-	-	S	-	-	-	DoxX
MDKIOEFL_03363	0.0	yfiC3	-	-	V	ko:K06147	-	ko00000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
MDKIOEFL_03364	0.0	yfiB3	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
MDKIOEFL_03365	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MDKIOEFL_03366	5.03e-180	-	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
MDKIOEFL_03367	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MDKIOEFL_03368	1.6e-60	yfjA	-	-	S	-	-	-	Belongs to the WXG100 family
MDKIOEFL_03369	1.12e-269	yfjB	-	-	-	-	-	-	-
MDKIOEFL_03370	2.5e-185	yfjC	-	-	-	-	-	-	-
MDKIOEFL_03371	6.08e-131	yfjD	-	-	S	-	-	-	Family of unknown function (DUF5381)
MDKIOEFL_03372	1.3e-101	-	-	-	S	-	-	-	Family of unknown function (DUF5381)
MDKIOEFL_03373	3.03e-74	yfjF	-	-	S	ko:K09771	-	ko00000,ko02000	UPF0060 membrane protein
MDKIOEFL_03374	8.16e-36	sspH	-	-	S	ko:K06425	-	ko00000	Belongs to the SspH family
MDKIOEFL_03375	0.0	acoR	-	-	KQ	ko:K21405	-	ko00000,ko03000	COG3284 Transcriptional activator of acetoin glycerol metabolism
MDKIOEFL_03376	0.0	acoL	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MDKIOEFL_03377	1.63e-262	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MDKIOEFL_03378	1.59e-243	acoB	-	-	C	ko:K21417	-	ko00000,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MDKIOEFL_03379	1.36e-244	acoA	-	-	C	ko:K21416	-	ko00000,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MDKIOEFL_03381	3.74e-108	yfjM	-	-	S	-	-	-	Psort location Cytoplasmic, score
MDKIOEFL_03382	4.72e-241	yfjN	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MDKIOEFL_03383	3.04e-59	-	-	-	S	-	-	-	YfzA-like protein
MDKIOEFL_03384	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MDKIOEFL_03385	2.76e-214	yfjP	3.2.2.21	-	L	ko:K01247	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MDKIOEFL_03386	7.8e-237	corA	-	-	P	ko:K03284	-	ko00000,ko02000	Mediates influx of magnesium ions
MDKIOEFL_03387	4.43e-190	yfjR	-	-	I	-	-	-	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
MDKIOEFL_03388	7.24e-198	pdaA	-	-	G	ko:K01567	-	ko00000,ko01000	deacetylase
MDKIOEFL_03389	3.26e-36	yfjT	-	-	-	-	-	-	-
MDKIOEFL_03390	1.76e-283	yfkA	-	-	S	-	-	-	YfkB-like domain
MDKIOEFL_03391	4.44e-191	yfkC	-	-	M	-	-	-	Mechanosensitive ion channel
MDKIOEFL_03392	3.69e-189	yfkD	-	-	S	-	-	-	YfkD-like protein
MDKIOEFL_03393	1.34e-235	cax	-	-	P	ko:K07300	-	ko00000,ko02000	COG0387 Ca2 H antiporter
MDKIOEFL_03394	1.9e-278	yfkF	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MDKIOEFL_03395	1.64e-12	-	-	-	-	-	-	-	-
MDKIOEFL_03396	9.64e-184	yihY	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
MDKIOEFL_03397	1.03e-66	yfkI	-	-	S	-	-	-	gas vesicle protein
MDKIOEFL_03398	9.78e-107	yfkJ	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MDKIOEFL_03399	5.99e-41	yfkK	-	-	S	-	-	-	Belongs to the UPF0435 family
MDKIOEFL_03400	6.21e-266	ydiN3	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MDKIOEFL_03401	1.11e-113	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
MDKIOEFL_03402	0.0	yfkN	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MDKIOEFL_03403	6.16e-160	frp	-	-	C	-	-	-	nitroreductase
MDKIOEFL_03404	1.24e-172	treR	-	-	K	ko:K03486	-	ko00000,ko03000	transcriptional
MDKIOEFL_03405	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
MDKIOEFL_03406	0.0	treP	2.7.1.201	-	G	ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MDKIOEFL_03407	0.0	yfkQ	-	-	EG	ko:K06295,ko:K06307	-	ko00000	Spore germination protein
MDKIOEFL_03408	1.26e-268	yfkR	-	-	S	ko:K06297,ko:K06308	-	ko00000	spore germination
MDKIOEFL_03410	7.02e-246	yfkT	-	-	E	ko:K06309	-	ko00000	Spore germination protein
MDKIOEFL_03411	0.0	yflA	-	-	E	ko:K03310	-	ko00000	Sodium alanine symporter
MDKIOEFL_03412	2.2e-86	ydhN1	-	-	S	-	-	-	Domain of unknown function (DUF1992)
MDKIOEFL_03413	0.0	yflE	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
MDKIOEFL_03414	0.0	nagE	2.7.1.193, 2.7.1.199	-	G	ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
MDKIOEFL_03415	1.14e-178	yflG	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
MDKIOEFL_03416	3.63e-66	yflH	-	-	S	-	-	-	Protein of unknown function (DUF3243)
MDKIOEFL_03417	6.9e-27	yflI	-	-	-	-	-	-	-
MDKIOEFL_03418	3.16e-25	yflJ	-	-	S	-	-	-	Protein of unknown function (DUF2639)
MDKIOEFL_03419	1.83e-135	yflK	-	-	S	-	-	-	protein conserved in bacteria
MDKIOEFL_03420	2.97e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
MDKIOEFL_03421	1.95e-275	nos	1.14.14.47	-	C	ko:K00491	ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
MDKIOEFL_03422	9.84e-192	yflN	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
MDKIOEFL_03423	5.35e-288	citM	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
MDKIOEFL_03424	5.66e-230	yflP	-	-	S	-	-	-	Tripartite tricarboxylate transporter family receptor
MDKIOEFL_03425	9.33e-153	citT	-	-	T	ko:K11638	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
MDKIOEFL_03426	1.64e-251	citS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
MDKIOEFL_03427	1.25e-101	citS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
MDKIOEFL_03428	0.0	yflS	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
MDKIOEFL_03429	7.03e-307	pel	4.2.2.2	-	G	ko:K01728	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectate lyase
MDKIOEFL_03430	1.71e-76	yflT	-	-	S	-	-	-	Heat induced stress protein YflT
MDKIOEFL_03431	1.06e-31	-	-	-	S	-	-	-	Protein of unknown function (DUF3212)
MDKIOEFL_03432	6.5e-218	yfmC	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
MDKIOEFL_03433	8.17e-221	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MDKIOEFL_03434	8.54e-223	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MDKIOEFL_03435	1.4e-192	fhuC	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
MDKIOEFL_03436	1.92e-238	yfmJ	-	-	S	ko:K07119	-	ko00000	N-terminal domain of oxidoreductase
MDKIOEFL_03437	3.75e-98	yfmK	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	acetyltransferase
MDKIOEFL_03438	7.25e-264	yfmL	-	-	L	-	-	-	COG0513 Superfamily II DNA and RNA helicases
MDKIOEFL_03439	0.0	yheS_1	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MDKIOEFL_03440	3.95e-74	-	-	-	-	-	-	-	-
MDKIOEFL_03442	9.1e-23	-	-	-	-	-	-	-	-
MDKIOEFL_03443	4.96e-64	-	-	-	O	-	-	-	Subtilase family
MDKIOEFL_03444	2.42e-263	yfmO	-	-	EGP	ko:K08221	-	ko00000,ko02000	Major facilitator superfamily
MDKIOEFL_03445	1.44e-89	yfmP	-	-	K	ko:K21902	-	ko00000,ko03000	transcriptional
MDKIOEFL_03446	7.28e-96	yfmQ	-	-	S	-	-	-	Uncharacterised protein from bacillus cereus group
MDKIOEFL_03447	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MDKIOEFL_03448	5.14e-161	yfmS	-	-	NT	-	-	-	chemotaxis protein
MDKIOEFL_03449	0.0	yfmT	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MDKIOEFL_03450	3.41e-312	yfnA	-	-	E	ko:K03294	-	ko00000	amino acid
MDKIOEFL_03451	1.06e-167	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
MDKIOEFL_03452	6.21e-268	fsr	-	-	P	ko:K08223	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MDKIOEFL_03453	1.11e-241	yfnD	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
MDKIOEFL_03454	2.84e-285	yfnE	-	-	S	-	-	-	Glycosyltransferase like family 2
MDKIOEFL_03455	1.82e-227	yfnF	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
MDKIOEFL_03456	1.37e-219	yfnG	4.2.1.45, 4.2.1.46	-	M	ko:K01709,ko:K01710	ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	dehydratase
MDKIOEFL_03457	4.01e-186	yfnH	2.7.7.33	-	JM	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	ko00000,ko00001,ko01000	Nucleotidyl transferase
MDKIOEFL_03458	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
MDKIOEFL_03459	0.0	cypD	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
MDKIOEFL_03460	1.88e-249	yetN	-	-	S	-	-	-	Protein of unknown function (DUF3900)
MDKIOEFL_03462	1.78e-265	yetM	-	-	CH	-	-	-	FAD binding domain
MDKIOEFL_03463	1.86e-114	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MDKIOEFL_03464	2.04e-08	-	-	-	EG	-	-	-	EamA-like transporter family
MDKIOEFL_03465	2.55e-135	yetJ	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
MDKIOEFL_03466	3.81e-28	yezD	-	-	S	-	-	-	Uncharacterized small protein (DUF2292)
MDKIOEFL_03467	4.37e-185	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MDKIOEFL_03468	1.75e-44	-	-	-	-	-	-	-	-
MDKIOEFL_03469	2.47e-85	yetH	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MDKIOEFL_03470	4.67e-73	yetG	1.14.99.48	-	S	ko:K07145	ko00860,ko01110,map00860,map01110	ko00000,ko00001,ko01000	Antibiotic biosynthesis monooxygenase
MDKIOEFL_03471	1.81e-157	yetF	-	-	S	-	-	-	membrane
MDKIOEFL_03472	0.0	-	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
MDKIOEFL_03473	1.58e-208	-	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MDKIOEFL_03474	9.71e-226	lplB	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4209 ABC-type polysaccharide transport system, permease component
MDKIOEFL_03475	0.0	lplA	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MDKIOEFL_03476	0.0	yetA	-	-	-	-	-	-	-
MDKIOEFL_03477	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase activity
MDKIOEFL_03478	7.51e-159	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MDKIOEFL_03479	0.0	yesX	4.2.2.23, 4.2.2.24	PL11	E	ko:K18197,ko:K18198	-	ko00000,ko01000	cell wall organization
MDKIOEFL_03480	0.0	-	4.2.2.23, 4.2.2.24	PL11	E	ko:K18197,ko:K18198	-	ko00000,ko01000	cell wall organization
MDKIOEFL_03481	1.99e-145	-	-	-	S	-	-	-	Protein of unknown function, DUF624
MDKIOEFL_03482	3.58e-163	yesU	-	-	S	-	-	-	Domain of unknown function (DUF1961)
MDKIOEFL_03483	1.75e-162	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MDKIOEFL_03484	0.0	yesS	-	-	K	-	-	-	Transcriptional regulator
MDKIOEFL_03485	2.79e-254	-	3.2.1.172	GH105	S	ko:K15532	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
MDKIOEFL_03486	5.33e-212	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MDKIOEFL_03487	2.02e-218	yesP	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MDKIOEFL_03488	1.18e-313	yesO	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MDKIOEFL_03489	2.81e-257	-	-	-	K	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
MDKIOEFL_03490	0.0	yesM	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MDKIOEFL_03491	4.8e-133	yesL	-	-	S	-	-	-	Protein of unknown function, DUF624
MDKIOEFL_03493	8.04e-129	yesJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
MDKIOEFL_03494	1.04e-133	cotJC	-	-	P	ko:K06334	-	ko00000	Spore Coat
MDKIOEFL_03495	2.31e-61	cotJB	-	-	S	ko:K06333	-	ko00000	CotJB protein
MDKIOEFL_03496	3.8e-60	cotJA	-	-	S	ko:K06332	-	ko00000	Spore coat associated protein JA (CotJA)
MDKIOEFL_03497	3.37e-193	yesF	-	-	GM	-	-	-	NAD(P)H-binding
MDKIOEFL_03498	1.94e-104	yesE	-	-	S	ko:K06893	-	ko00000	SnoaL-like domain
MDKIOEFL_03499	1.16e-128	dhaR3	-	-	K	ko:K16137	-	ko00000,ko03000	Transcriptional regulator
MDKIOEFL_03501	1.48e-160	yeeN	-	-	K	-	-	-	transcriptional regulatory protein
MDKIOEFL_03503	5.56e-268	rapH	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Tetratricopeptide repeat
MDKIOEFL_03504	4.59e-15	-	-	-	S	-	-	-	Lysozyme inhibitor LprI
MDKIOEFL_03505	3.72e-211	-	-	-	S	-	-	-	amine dehydrogenase activity
MDKIOEFL_03506	2.3e-125	-	-	-	L	-	-	-	endonuclease activity
MDKIOEFL_03508	1.09e-230	-	-	-	S	-	-	-	Bacterial EndoU nuclease
MDKIOEFL_03509	8.47e-55	-	-	-	S	-	-	-	Immunity protein 22
MDKIOEFL_03511	4.21e-122	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
MDKIOEFL_03513	0.0	-	-	-	L	-	-	-	DEAD-like helicases superfamily
MDKIOEFL_03514	7.04e-111	-	-	-	-	-	-	-	-
MDKIOEFL_03515	0.0	rlmCD	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MDKIOEFL_03516	1.8e-218	dagK	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MDKIOEFL_03517	0.0	swrC	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MDKIOEFL_03518	4.03e-188	yerO	-	-	K	-	-	-	Transcriptional regulator
MDKIOEFL_03519	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MDKIOEFL_03521	7.37e-61	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MDKIOEFL_03522	0.0	putP	-	-	E	ko:K03307,ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MDKIOEFL_03523	2.29e-160	sapB	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
MDKIOEFL_03524	4.95e-250	yerI	-	-	S	-	-	-	homoserine kinase type II (protein kinase fold)
MDKIOEFL_03525	3.57e-281	camS	-	-	S	-	-	-	COG4851 Protein involved in sex pheromone biosynthesis
MDKIOEFL_03526	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MDKIOEFL_03527	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
MDKIOEFL_03528	1.1e-161	pcrB	-	-	I	ko:K07094	-	ko00000,ko01000	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
MDKIOEFL_03530	0.0	yerD	1.4.7.1	-	E	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	ko00000,ko00001,ko01000	Belongs to the glutamate synthase family
MDKIOEFL_03531	7.62e-68	yerC	-	-	S	-	-	-	protein conserved in bacteria
MDKIOEFL_03532	8.2e-245	yerB	-	-	S	-	-	-	Protein of unknown function (DUF3048) C-terminal domain
MDKIOEFL_03533	0.0	yerA	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	adenine deaminase
MDKIOEFL_03534	3.45e-37	-	-	-	S	-	-	-	Protein of unknown function (DUF2892)
MDKIOEFL_03535	4.11e-292	-	-	-	E	ko:K16263	-	ko00000,ko02000	Amino acid permease
MDKIOEFL_03536	1.45e-93	-	-	-	K	-	-	-	helix_turn_helix ASNC type
MDKIOEFL_03537	2.32e-297	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
MDKIOEFL_03538	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
MDKIOEFL_03539	1.04e-136	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MDKIOEFL_03540	9.88e-240	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
MDKIOEFL_03541	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MDKIOEFL_03542	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MDKIOEFL_03543	1.15e-167	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MDKIOEFL_03544	3.79e-52	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MDKIOEFL_03545	1.44e-168	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
MDKIOEFL_03546	2.81e-314	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MDKIOEFL_03547	7.15e-276	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MDKIOEFL_03548	2.28e-108	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MDKIOEFL_03549	3.13e-38	yebG	-	-	S	-	-	-	NETI protein
MDKIOEFL_03550	1.08e-119	yebE	-	-	S	-	-	-	UPF0316 protein
MDKIOEFL_03552	8.31e-165	yebC	-	-	M	-	-	-	Membrane
MDKIOEFL_03553	2.41e-283	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MDKIOEFL_03554	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4179)
MDKIOEFL_03555	1.05e-109	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MDKIOEFL_03556	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
MDKIOEFL_03557	0.0	yebA	-	-	E	-	-	-	COG1305 Transglutaminase-like enzymes
MDKIOEFL_03558	2.63e-284	yeaD	-	-	S	-	-	-	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
MDKIOEFL_03559	3.96e-226	yeaC	-	-	S	ko:K03924	-	ko00000,ko01000	COG0714 MoxR-like ATPases
MDKIOEFL_03560	8.34e-197	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MDKIOEFL_03561	0.0	gabP	-	-	E	ko:K11735	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
MDKIOEFL_03562	0.0	cotA	1.16.3.3	-	Q	ko:K06324	-	ko00000,ko01000	multicopper oxidases
MDKIOEFL_03563	1.27e-224	yeaA	-	-	S	-	-	-	Protein of unknown function (DUF4003)
MDKIOEFL_03564	2.33e-198	-	-	-	I	-	-	-	Alpha/beta hydrolase family
MDKIOEFL_03565	8.2e-48	ydjO	-	-	S	-	-	-	Cold-inducible protein YdjO
MDKIOEFL_03567	2.31e-207	ydjN	-	-	U	-	-	-	Involved in the tonB-independent uptake of proteins
MDKIOEFL_03568	1.79e-84	ydjM	-	-	M	-	-	-	Lytic transglycolase
MDKIOEFL_03569	3.5e-249	ydjL	1.1.1.264, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00098	ko00650,map00650	ko00000,ko00001,ko01000	Dehydrogenase
MDKIOEFL_03570	0.0	iolT	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MDKIOEFL_03571	4.59e-247	-	-	-	S	-	-	-	Ion transport 2 domain protein
MDKIOEFL_03572	1.71e-201	ydjI	-	-	S	-	-	-	virion core protein (lumpy skin disease virus)
MDKIOEFL_03573	4.44e-174	ydjH	-	-	S	ko:K06872	-	ko00000	COG1512 Beta-propeller domains of methanol dehydrogenase type
MDKIOEFL_03574	4.25e-227	ydjG	-	-	L	-	-	-	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MDKIOEFL_03575	3.1e-147	pspA	-	-	KT	ko:K03969	-	ko00000	Phage shock protein A
MDKIOEFL_03576	1.73e-220	ydjE	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
MDKIOEFL_03577	0.0	gutP	-	-	G	ko:K03292,ko:K16248	-	ko00000,ko02000	MFS/sugar transport protein
MDKIOEFL_03578	4.32e-258	gutB	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
MDKIOEFL_03579	0.0	gutR	-	-	K	ko:K16247	-	ko00000,ko03000	NB-ARC domain
MDKIOEFL_03580	2.31e-194	ydjC	-	-	S	-	-	-	Abhydrolase domain containing 18
MDKIOEFL_03581	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MDKIOEFL_03582	2.14e-58	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MDKIOEFL_03583	3e-167	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MDKIOEFL_03584	3.2e-37	ydiK	-	-	S	-	-	-	Domain of unknown function (DUF4305)
MDKIOEFL_03585	3.55e-161	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MDKIOEFL_03586	5.48e-31	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MDKIOEFL_03587	2.14e-148	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MDKIOEFL_03588	1.46e-117	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
MDKIOEFL_03589	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
MDKIOEFL_03590	1.34e-240	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MDKIOEFL_03591	1.41e-108	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MDKIOEFL_03592	3.27e-159	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	COG1214 Inactive homolog of metal-dependent proteases
MDKIOEFL_03593	2.13e-111	ydiB	-	-	S	ko:K06925	-	ko00000,ko03016	ATPase or kinase
MDKIOEFL_03594	2.59e-229	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MDKIOEFL_03599	4.94e-13	-	-	-	-	-	-	-	-
MDKIOEFL_03600	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
MDKIOEFL_03601	4.05e-89	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	transcriptional
MDKIOEFL_03602	1.67e-310	ynbB	-	-	P	-	-	-	COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
MDKIOEFL_03603	6.07e-292	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MDKIOEFL_03604	2.29e-226	spoVK	-	-	O	ko:K06413	-	ko00000	stage V sporulation protein K
MDKIOEFL_03605	2.72e-148	cwlC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
MDKIOEFL_03606	3.05e-139	-	-	-	-	-	-	-	-
MDKIOEFL_03607	1.65e-243	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MDKIOEFL_03608	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MDKIOEFL_03609	5.01e-66	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
MDKIOEFL_03610	1.2e-30	ymzA	-	-	-	-	-	-	-
MDKIOEFL_03611	9.4e-31	-	-	-	-	-	-	-	-
MDKIOEFL_03612	1.28e-45	hfq	-	-	J	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	ko00000,ko00001,ko03019,ko03036	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
MDKIOEFL_03613	1.38e-223	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MDKIOEFL_03614	5.41e-76	ymaF	-	-	S	-	-	-	YmaF family
MDKIOEFL_03616	2.02e-66	ebrA	-	-	P	ko:K11814	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
MDKIOEFL_03617	1.57e-73	ebrB	-	-	P	ko:K03297,ko:K11814,ko:K11815	-	ko00000,ko00002,ko02000	COG2076 Membrane transporters of cations and cationic drugs
MDKIOEFL_03618	1.71e-104	ymaD	-	-	O	-	-	-	redox protein, regulator of disulfide bond formation
MDKIOEFL_03619	3.96e-163	ymaC	-	-	S	-	-	-	Replication protein
MDKIOEFL_03621	0.0	aprX	-	-	O	ko:K17734	-	ko00000,ko01000,ko01002	Belongs to the peptidase S8 family
MDKIOEFL_03622	8.93e-206	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
MDKIOEFL_03623	8.03e-81	ymzB	-	-	-	-	-	-	-
MDKIOEFL_03624	1.02e-134	pksA	-	-	K	-	-	-	Transcriptional regulator
MDKIOEFL_03625	9.3e-126	ymcC	-	-	S	-	-	-	Membrane
MDKIOEFL_03627	1.35e-89	-	-	-	S	-	-	-	Regulatory protein YrvL
MDKIOEFL_03628	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MDKIOEFL_03629	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MDKIOEFL_03630	1.74e-119	cotE	-	-	S	ko:K06328	-	ko00000	Spore coat protein
MDKIOEFL_03631	1.27e-89	ymcA	3.6.3.21	-	S	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	Belongs to the UPF0342 family
MDKIOEFL_03632	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MDKIOEFL_03633	1.69e-277	kbl	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MDKIOEFL_03634	7.97e-251	tdh	1.1.1.103	-	C	ko:K00060	ko00260,map00260	ko00000,ko00001,ko01000	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
MDKIOEFL_03635	2.44e-49	spoVS	-	-	S	ko:K06416	-	ko00000	Stage V sporulation protein S
MDKIOEFL_03636	6.18e-195	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	protein conserved in bacteria
MDKIOEFL_03637	4.25e-306	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
MDKIOEFL_03638	1.1e-277	pbpX	-	-	V	-	-	-	Beta-lactamase
MDKIOEFL_03639	4.7e-239	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MDKIOEFL_03640	3.71e-300	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
MDKIOEFL_03641	3.34e-132	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MDKIOEFL_03642	8.75e-177	ymfM	-	-	S	ko:K15539	-	ko00000	protein conserved in bacteria
MDKIOEFL_03643	3.91e-183	ymfK	-	-	S	-	-	-	Protein of unknown function (DUF3388)
MDKIOEFL_03644	5.13e-55	ymfJ	-	-	S	-	-	-	Protein of unknown function (DUF3243)
MDKIOEFL_03645	3.01e-166	ymfI	1.1.1.100	-	S	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
MDKIOEFL_03646	4.79e-309	ymfH	-	-	S	-	-	-	zinc protease
MDKIOEFL_03647	3.17e-297	albE	-	-	S	-	-	-	Peptidase M16
MDKIOEFL_03648	5.1e-266	ymfD	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MDKIOEFL_03649	1.28e-171	ymfC	-	-	K	ko:K03710	-	ko00000,ko03000	Transcriptional regulator
MDKIOEFL_03650	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
MDKIOEFL_03651	4.94e-44	-	-	-	S	-	-	-	YlzJ-like protein
MDKIOEFL_03652	5.01e-171	tepA	-	-	OU	-	-	-	COG0740 Protease subunit of ATP-dependent Clp proteases
MDKIOEFL_03653	0.0	rnjB	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MDKIOEFL_03654	6.39e-201	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MDKIOEFL_03655	4.9e-283	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
MDKIOEFL_03656	1.66e-247	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MDKIOEFL_03657	8.17e-141	spoVFB	-	-	H	ko:K06411	-	ko00000	Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
MDKIOEFL_03658	2.16e-207	dpaA	-	-	CH	ko:K06410	-	ko00000	Dipicolinate synthase subunit A
MDKIOEFL_03659	1.53e-56	ymxH	-	-	S	-	-	-	YlmC YmxH family
MDKIOEFL_03660	1.62e-295	mlpA	-	-	S	-	-	-	Belongs to the peptidase M16 family
MDKIOEFL_03661	2.4e-231	ylxY	-	-	G	-	-	-	Sporulation protein, polysaccharide deacetylase
MDKIOEFL_03662	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MDKIOEFL_03663	7.11e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MDKIOEFL_03664	9.42e-232	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
MDKIOEFL_03665	7.05e-219	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MDKIOEFL_03666	3.29e-75	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MDKIOEFL_03667	1.11e-59	ylxP	-	-	S	ko:K09764	-	ko00000	protein conserved in bacteria
MDKIOEFL_03668	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MDKIOEFL_03669	6.16e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
MDKIOEFL_03670	2.01e-57	ylxR	-	-	K	ko:K07742	-	ko00000	nucleic-acid-binding protein implicated in transcription termination
MDKIOEFL_03671	5.49e-261	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
MDKIOEFL_03672	1.34e-104	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
MDKIOEFL_03673	2.24e-58	-	-	-	V	ko:K20484	ko02020,ko02024,map02020,map02024	ko00000,ko00001	PFAM Lanthionine synthetase
MDKIOEFL_03674	5.12e-144	-	-	-	V	ko:K06147,ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC superfamily ATP binding cassette transporter, ABC
MDKIOEFL_03675	3.11e-158	bsaB	-	-	S	ko:K20483	ko02020,ko02024,map02020,map02024	ko00000,ko00001	Lantibiotic dehydratase, C terminus
MDKIOEFL_03677	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MDKIOEFL_03678	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MDKIOEFL_03679	4.72e-285	rasP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
MDKIOEFL_03680	1.39e-276	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MDKIOEFL_03681	1.65e-178	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
MDKIOEFL_03682	3.84e-187	uppS	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MDKIOEFL_03683	9.6e-119	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MDKIOEFL_03684	5.82e-163	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
MDKIOEFL_03685	9.82e-202	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MDKIOEFL_03686	1.49e-168	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
MDKIOEFL_03687	4e-100	ylxL	-	-	-	-	-	-	-
MDKIOEFL_03688	1.33e-175	sigD	-	-	K	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	ko00000,ko00001,ko02035,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MDKIOEFL_03689	3.34e-112	cheD	3.5.1.44	-	NT	ko:K03411	ko02030,map02030	ko00000,ko00001,ko01000,ko02035	Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
MDKIOEFL_03690	5.06e-144	cheC	-	-	NT	ko:K03410	ko02030,map02030	ko00000,ko00001,ko02035	COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
MDKIOEFL_03691	1.56e-103	cheW	-	-	NT	ko:K03408	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	COG0835 Chemotaxis signal transduction protein
MDKIOEFL_03692	0.0	cheA	2.7.13.3	-	NT	ko:K03407	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	COG0643 Chemotaxis protein histidine kinase and related kinases
MDKIOEFL_03693	1.81e-252	cheB	3.1.1.61, 3.5.1.44	-	NT	ko:K03412	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
MDKIOEFL_03694	3.14e-200	ylxH	-	-	D	ko:K04562	-	ko00000,ko02035	Belongs to the ParA family
MDKIOEFL_03695	5.65e-256	flhF	-	-	N	ko:K02404	-	ko00000,ko02035	Flagellar biosynthesis regulator FlhF
MDKIOEFL_03696	0.0	flhA	-	-	N	ko:K02400	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MDKIOEFL_03697	3.89e-244	flhB	-	-	N	ko:K02401	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MDKIOEFL_03698	1.47e-170	fliR	-	-	N	ko:K02421	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthetic protein FliR
MDKIOEFL_03699	5.23e-50	fliQ	-	-	N	ko:K02420	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Role in flagellar biosynthesis
MDKIOEFL_03700	1.21e-141	fliP	-	-	N	ko:K02419	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Plays a role in the flagellum-specific transport system
MDKIOEFL_03701	1.07e-134	fliZ	-	-	N	ko:K02418	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthesis protein, FliO
MDKIOEFL_03702	1.22e-76	cheY	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	response regulator
MDKIOEFL_03703	1.38e-253	fliY	-	-	N	ko:K02417	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035,ko02044	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MDKIOEFL_03704	6.61e-231	fliM	-	-	N	ko:K02416	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MDKIOEFL_03705	5.59e-78	fliL	-	-	N	ko:K02415	-	ko00000,ko02035	Controls the rotational direction of flagella during chemotaxis
MDKIOEFL_03706	1.09e-179	flgG	-	-	N	ko:K02390	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod
MDKIOEFL_03707	2.81e-96	flgD	-	-	N	ko:K02389	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod modification protein
MDKIOEFL_03708	3.71e-304	fliK	-	-	N	ko:K02414	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-length control protein
MDKIOEFL_03709	1.51e-78	ylxF	-	-	S	-	-	-	MgtE intracellular N domain
MDKIOEFL_03710	1.79e-91	fliJ	-	-	N	ko:K02413	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar biosynthesis chaperone
MDKIOEFL_03711	4.08e-306	fliI	3.6.3.14	-	NU	ko:K02412	ko02040,map02040	ko00000,ko00001,ko01000,ko02035,ko02044	COG1157 Flagellar biosynthesis type III secretory pathway ATPase
MDKIOEFL_03712	1.92e-144	fliH	-	-	NU	ko:K02411	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	COG1317 Flagellar biosynthesis type III secretory pathway protein
MDKIOEFL_03713	6.08e-230	fliG	-	-	N	ko:K02410	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MDKIOEFL_03714	0.0	fliF	-	-	N	ko:K02409	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	The M ring may be actively involved in energy transduction
MDKIOEFL_03715	5.5e-53	fliE	-	-	N	ko:K02408	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-basal body
MDKIOEFL_03716	8.81e-98	flgC	-	-	N	ko:K02388	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the flagella basal body rod proteins family
MDKIOEFL_03717	1.62e-83	flgB	-	-	N	ko:K02387	ko02040,map02040	ko00000,ko00001,ko02035	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
MDKIOEFL_03718	1.95e-175	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MDKIOEFL_03719	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MDKIOEFL_03720	3.01e-120	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MDKIOEFL_03721	1.13e-217	xerC	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	tyrosine recombinase XerC
MDKIOEFL_03722	2.22e-313	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MDKIOEFL_03723	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MDKIOEFL_03724	3.62e-215	dprA	-	-	LU	ko:K04096	-	ko00000	Rossmann fold nucleotide-binding protein involved in DNA uptake
MDKIOEFL_03725	3.09e-213	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MDKIOEFL_03726	6.77e-269	sucC	6.2.1.5	-	C	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MDKIOEFL_03727	1.7e-59	ylqH	-	-	S	ko:K04061	-	ko00000,ko02044	homolog of the cytoplasmic domain of flagellar protein FhlB
MDKIOEFL_03728	0.0	ylqG	-	-	-	-	-	-	-
MDKIOEFL_03729	2.04e-175	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MDKIOEFL_03730	5.7e-200	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MDKIOEFL_03731	8.14e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MDKIOEFL_03732	2.41e-177	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
MDKIOEFL_03733	1.84e-122	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MDKIOEFL_03734	3.41e-80	ylqD	-	-	S	-	-	-	YlqD protein
MDKIOEFL_03735	1.2e-49	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
MDKIOEFL_03736	1.13e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
MDKIOEFL_03737	3.95e-308	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MDKIOEFL_03738	8.01e-66	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MDKIOEFL_03739	1.67e-114	-	-	-	-	-	-	-	-
MDKIOEFL_03740	3.38e-227	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MDKIOEFL_03741	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
MDKIOEFL_03742	2.12e-174	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MDKIOEFL_03743	1.15e-43	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MDKIOEFL_03744	3.5e-167	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
MDKIOEFL_03745	7.58e-218	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
MDKIOEFL_03746	8.33e-230	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MDKIOEFL_03747	6.22e-121	fapR	-	-	K	-	-	-	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
MDKIOEFL_03748	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MDKIOEFL_03749	3.4e-201	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
MDKIOEFL_03750	5.89e-153	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
MDKIOEFL_03751	0.0	yloV	-	-	S	ko:K07030	-	ko00000	kinase related to dihydroxyacetone kinase
MDKIOEFL_03752	3.65e-78	yloU	-	-	S	-	-	-	protein conserved in bacteria
MDKIOEFL_03753	7.06e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
MDKIOEFL_03754	1.64e-156	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
MDKIOEFL_03755	4.68e-153	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
MDKIOEFL_03756	4.57e-214	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MDKIOEFL_03757	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
MDKIOEFL_03758	3.54e-180	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
MDKIOEFL_03759	3.07e-263	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MDKIOEFL_03760	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MDKIOEFL_03761	1.49e-224	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MDKIOEFL_03762	4.8e-109	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MDKIOEFL_03763	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MDKIOEFL_03764	7.28e-286	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MDKIOEFL_03765	6.21e-39	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MDKIOEFL_03766	5.73e-143	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
MDKIOEFL_03767	3.97e-54	ylzA	-	-	S	ko:K09777	-	ko00000	Belongs to the UPF0296 family
MDKIOEFL_03768	8.41e-202	yloC	-	-	S	-	-	-	stress-induced protein
MDKIOEFL_03769	0.0	yloB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	COG0474 Cation transport ATPase
MDKIOEFL_03770	0.0	FbpA	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
MDKIOEFL_03771	4.41e-106	sirC	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Siroheme synthase
MDKIOEFL_03772	3.41e-186	sirB	4.99.1.4	-	S	ko:K03794	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sirohydrochlorin ferrochelatase
MDKIOEFL_03773	5.9e-185	cobA	2.1.1.107	-	H	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
MDKIOEFL_03774	1.59e-141	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
MDKIOEFL_03775	2.15e-284	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
MDKIOEFL_03776	1.04e-229	cysP	-	-	P	ko:K16331	-	ko00000,ko02000	phosphate transporter
MDKIOEFL_03777	5.95e-182	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
MDKIOEFL_03778	8.96e-149	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MDKIOEFL_03779	6.56e-164	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MDKIOEFL_03780	4.26e-221	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MDKIOEFL_03781	4.31e-182	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
MDKIOEFL_03782	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarB family
MDKIOEFL_03783	1.31e-269	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
MDKIOEFL_03784	0.0	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MDKIOEFL_03785	4.4e-215	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
MDKIOEFL_03786	2.24e-295	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Xanthine uracil
MDKIOEFL_03787	4.45e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MDKIOEFL_03788	3.52e-225	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MDKIOEFL_03789	2.71e-103	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MDKIOEFL_03790	3.74e-82	ylyA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
MDKIOEFL_03791	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MDKIOEFL_03792	6.44e-100	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	Cell division initiation protein
MDKIOEFL_03793	4.28e-178	ylmH	-	-	S	-	-	-	conserved protein, contains S4-like domain
MDKIOEFL_03794	1.74e-53	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	membrane
MDKIOEFL_03795	4.47e-87	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MDKIOEFL_03796	9.03e-162	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MDKIOEFL_03797	9.17e-204	ylmD	-	-	S	ko:K05810	-	ko00000,ko01000	Belongs to the multicopper oxidase YfiH RL5 family
MDKIOEFL_03798	3.58e-51	ylmC	-	-	S	-	-	-	sporulation protein
MDKIOEFL_03799	0.0	argE	-	-	E	ko:K20895	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Acetylornithine deacetylase
MDKIOEFL_03800	1.29e-187	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
MDKIOEFL_03801	7.99e-180	sigG	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MDKIOEFL_03802	1.48e-160	sigE	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MDKIOEFL_03803	7.14e-219	spoIIGA	-	-	M	ko:K06383	-	ko00000,ko01000,ko01002	aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
MDKIOEFL_03804	0.0	bpr	-	-	O	ko:K13276	-	ko00000,ko01000,ko01002,ko03110	COG1404 Subtilisin-like serine proteases
MDKIOEFL_03805	1.84e-260	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MDKIOEFL_03806	4.88e-299	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MDKIOEFL_03807	5.37e-76	sbp	-	-	S	-	-	-	small basic protein
MDKIOEFL_03808	1.23e-131	ylxX	-	-	S	-	-	-	protein conserved in bacteria
MDKIOEFL_03809	2.23e-142	ylxW	-	-	S	-	-	-	protein conserved in bacteria
MDKIOEFL_03810	3.37e-178	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MDKIOEFL_03811	3.74e-211	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	cell wall formation
MDKIOEFL_03812	4.48e-256	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MDKIOEFL_03813	6.64e-237	spoVE	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
MDKIOEFL_03814	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MDKIOEFL_03815	9.59e-220	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MDKIOEFL_03816	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MDKIOEFL_03817	0.0	spoVD	-	-	M	ko:K08384	ko00550,map00550	ko00000,ko00001,ko01011	stage V sporulation protein D
MDKIOEFL_03818	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MDKIOEFL_03819	3.42e-68	ftsL	-	-	D	-	-	-	Essential cell division protein
MDKIOEFL_03820	1.66e-218	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MDKIOEFL_03821	4e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
MDKIOEFL_03822	0.0	bshC	-	-	S	ko:K22136	-	ko00000	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
MDKIOEFL_03823	1.66e-216	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MDKIOEFL_03824	1.33e-115	ylbP	-	-	K	-	-	-	n-acetyltransferase
MDKIOEFL_03825	4.72e-107	ylbO	-	-	S	ko:K06314	-	ko00000,ko03000	SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
MDKIOEFL_03826	1.71e-37	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
MDKIOEFL_03827	6.94e-117	ylbN	-	-	S	ko:K07040	-	ko00000	metal-binding, possibly nucleic acid-binding protein
MDKIOEFL_03829	8.29e-292	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
MDKIOEFL_03830	7.81e-239	ylbL	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
MDKIOEFL_03831	1.48e-175	ylbK	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
MDKIOEFL_03832	1.84e-280	ylbJ	-	-	S	-	-	-	Sporulation integral membrane protein YlbJ
MDKIOEFL_03833	3.8e-111	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MDKIOEFL_03834	6.07e-126	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Methyltransferase
MDKIOEFL_03835	4.36e-52	ylbG	-	-	S	-	-	-	UPF0298 protein
MDKIOEFL_03836	2.34e-97	ylbF	-	-	S	-	-	-	Belongs to the UPF0342 family
MDKIOEFL_03837	1.73e-48	ylbE	-	-	S	-	-	-	YlbE-like protein
MDKIOEFL_03838	3.24e-89	ylbD	-	-	S	-	-	-	Putative coat protein
MDKIOEFL_03839	3.09e-256	ylbC	-	-	S	-	-	-	protein with SCP PR1 domains
MDKIOEFL_03840	1.08e-97	ylbB	-	-	T	-	-	-	COG0517 FOG CBS domain
MDKIOEFL_03841	1.61e-81	ylbA	-	-	S	-	-	-	YugN-like family
MDKIOEFL_03842	1.21e-213	ctaG	-	-	S	ko:K02862	-	ko00000	cytochrome c oxidase
MDKIOEFL_03843	6.09e-70	ctaF	1.9.3.1	-	C	ko:K02277	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
MDKIOEFL_03844	1.84e-145	ctaE	1.9.3.1	-	C	ko:K02276	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
MDKIOEFL_03845	0.0	ctaD	1.9.3.1	-	C	ko:K02274	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MDKIOEFL_03846	2.38e-252	ctaC	1.9.3.1	-	C	ko:K02275	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
MDKIOEFL_03847	1.7e-208	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MDKIOEFL_03848	2.85e-212	ctaA	-	-	O	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	ko00000,ko00001,ko00002,ko03029	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
MDKIOEFL_03849	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MDKIOEFL_03850	7.05e-271	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
MDKIOEFL_03851	6.94e-59	ylaN	-	-	S	-	-	-	Belongs to the UPF0358 family
MDKIOEFL_03852	2.87e-218	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
MDKIOEFL_03853	9.32e-112	ylaL	-	-	S	-	-	-	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MDKIOEFL_03854	4.7e-316	ylaK	-	-	T	ko:K07175	-	ko00000	ATPase related to phosphate starvation-inducible protein PhoH
MDKIOEFL_03855	1.64e-124	ylaJ	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MDKIOEFL_03856	8.92e-44	ylaI	-	-	S	-	-	-	protein conserved in bacteria
MDKIOEFL_03857	8.88e-63	ylaH	-	-	S	-	-	-	YlaH-like protein
MDKIOEFL_03858	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
MDKIOEFL_03859	2.21e-30	-	-	-	S	-	-	-	Family of unknown function (DUF5325)
MDKIOEFL_03860	5.7e-56	ylaE	-	-	-	-	-	-	-
MDKIOEFL_03862	8.39e-114	ylaC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MDKIOEFL_03863	1.18e-55	ylaB	-	-	-	-	-	-	-
MDKIOEFL_03864	0.0	ylaA	-	-	-	-	-	-	-
MDKIOEFL_03865	0.0	mpl	3.4.24.28, 3.4.24.29	-	E	ko:K01400,ko:K01401,ko:K19351	ko01503,ko05150,map01503,map05150	ko00000,ko00001,ko01000,ko01002	Peptidase M4
MDKIOEFL_03866	1.17e-219	-	-	-	Q	-	-	-	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MDKIOEFL_03867	4.07e-98	ykzC	-	-	S	-	-	-	Acetyltransferase (GNAT) family
MDKIOEFL_03868	2.61e-192	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase
MDKIOEFL_03869	4.48e-35	ykzI	-	-	-	-	-	-	-
MDKIOEFL_03870	2.15e-151	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
MDKIOEFL_03871	6.37e-55	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
MDKIOEFL_03872	0.0	speA	4.1.1.17, 4.1.1.19	-	E	ko:K01581,ko:K01585	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Arginine
MDKIOEFL_03873	4.55e-83	slp	-	-	CO	-	-	-	COG0526, thiol-disulfide isomerase and thioredoxins
MDKIOEFL_03874	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MDKIOEFL_03875	2.32e-298	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MDKIOEFL_03876	3.52e-227	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MDKIOEFL_03877	1.06e-258	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MDKIOEFL_03878	1.06e-138	ykyA	-	-	L	-	-	-	Putative cell-wall binding lipoprotein
MDKIOEFL_03879	1.26e-07	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
MDKIOEFL_03880	3.96e-131	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MDKIOEFL_03881	1.18e-186	ykrA	-	-	S	-	-	-	hydrolases of the HAD superfamily
MDKIOEFL_03882	8.98e-42	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
MDKIOEFL_03883	0.0	rnjA	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MDKIOEFL_03884	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MDKIOEFL_03885	1.68e-148	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
MDKIOEFL_03886	1.19e-198	ykqA	-	-	P	-	-	-	Gamma-glutamyl cyclotransferase, AIG2-like
MDKIOEFL_03887	4.59e-307	kinC	2.7.13.3	-	T	ko:K07698	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
MDKIOEFL_03888	2.63e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	of stationary sporulation gene expression
MDKIOEFL_03889	6.17e-234	mreBH	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod-share determining protein MreBH
MDKIOEFL_03890	1.09e-18	-	-	-	S	-	-	-	Uncharacterized protein YkpC
MDKIOEFL_03891	2.07e-303	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	COG2309 Leucyl aminopeptidase (aminopeptidase T)
MDKIOEFL_03892	2.35e-214	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MDKIOEFL_03893	0.0	ykpA	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MDKIOEFL_03894	5.43e-52	ykoA	-	-	-	-	-	-	-
MDKIOEFL_03895	4.95e-134	sipT	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MDKIOEFL_03896	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
MDKIOEFL_03897	4.07e-215	pfkB	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family
MDKIOEFL_03898	7.41e-176	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	Transcriptional regulator
MDKIOEFL_03899	1.92e-265	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
MDKIOEFL_03900	3.53e-159	yknY	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MDKIOEFL_03901	2.34e-233	yknX	-	-	M	ko:K02005,ko:K13888	-	ko00000,ko00002,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MDKIOEFL_03902	6.23e-149	yknW	-	-	S	-	-	-	Yip1 domain
MDKIOEFL_03903	0.0	yknV	-	-	V	ko:K02021,ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
MDKIOEFL_03904	0.0	yknU	-	-	V	ko:K06147,ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
MDKIOEFL_03905	1.15e-43	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MDKIOEFL_03906	1.1e-108	moaE	2.8.1.12	-	H	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	COG0314 Molybdopterin converting factor, large subunit
MDKIOEFL_03907	2.33e-120	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
MDKIOEFL_03908	1.38e-309	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	molybdopterin
MDKIOEFL_03909	8.86e-244	moeB	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MDKIOEFL_03910	3.75e-141	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
MDKIOEFL_03911	2.83e-199	yknT	-	-	-	ko:K06437	-	ko00000	-
MDKIOEFL_03912	1.78e-120	rok	-	-	K	-	-	-	Repressor of ComK
MDKIOEFL_03913	6.01e-104	ykuV	-	-	CO	-	-	-	thiol-disulfide
MDKIOEFL_03914	9.78e-130	ykuU	-	-	O	-	-	-	Alkyl hydroperoxide reductase
MDKIOEFL_03915	4.1e-181	ykuT	-	-	M	ko:K22044	-	ko00000,ko02000	Mechanosensitive ion channel
MDKIOEFL_03916	7.23e-51	ykuS	-	-	S	-	-	-	Belongs to the UPF0180 family
MDKIOEFL_03917	1.27e-272	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MDKIOEFL_03918	1.31e-125	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MDKIOEFL_03919	1.03e-101	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
MDKIOEFL_03920	1.01e-221	ykuO	-	-	-	-	-	-	-
MDKIOEFL_03921	3.53e-110	-	-	-	C	ko:K03839	-	ko00000	Flavodoxin domain
MDKIOEFL_03922	6.52e-216	ccpC	-	-	K	-	-	-	Transcriptional regulator
MDKIOEFL_03923	5.15e-100	ykuL	-	-	S	-	-	-	CBS domain
MDKIOEFL_03924	7.83e-38	ykzF	-	-	S	-	-	-	Antirepressor AbbA
MDKIOEFL_03925	3.73e-121	-	-	-	S	ko:K09776	-	ko00000	Ribonuclease H-like
MDKIOEFL_03926	5.16e-50	ykuJ	-	-	S	-	-	-	protein conserved in bacteria
MDKIOEFL_03927	3.55e-298	ykuI	-	-	T	-	-	-	Diguanylate phosphodiesterase
MDKIOEFL_03928	2.6e-182	fadH	1.3.1.34	-	IQ	ko:K00219	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MDKIOEFL_03929	9.98e-212	ykuE	-	-	S	ko:K07098	-	ko00000	Metallophosphoesterase
MDKIOEFL_03930	5.84e-115	ykuD	-	-	S	-	-	-	protein conserved in bacteria
MDKIOEFL_03931	2.55e-305	ykuC	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MDKIOEFL_03932	3.71e-110	ykyB	-	-	S	-	-	-	YkyB-like protein
MDKIOEFL_03933	4.95e-216	cheV	-	-	T	ko:K03408,ko:K03415	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	Chemotaxis protein CheV
MDKIOEFL_03934	1.05e-22	-	-	-	-	-	-	-	-
MDKIOEFL_03935	8.45e-283	patA	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MDKIOEFL_03936	0.0	kinA	2.7.13.3	-	T	ko:K02491	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MDKIOEFL_03937	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MDKIOEFL_03938	4.4e-171	ykwD	-	-	J	-	-	-	protein with SCP PR1 domains
MDKIOEFL_03939	1.68e-17	vgb	-	-	H	ko:K18235	-	ko00000,ko01000,ko01504	Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid
MDKIOEFL_03940	4.02e-203	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
MDKIOEFL_03941	0.0	mcpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MDKIOEFL_03942	1.07e-162	ykwB	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MDKIOEFL_03943	2.49e-256	splB	4.1.99.14	-	L	ko:K03716	-	ko00000,ko01000	Spore photoproduct lyase
MDKIOEFL_03944	6.27e-51	splA	-	-	S	ko:K06315	-	ko00000,ko03000	Transcriptional regulator
MDKIOEFL_03945	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MDKIOEFL_03946	1.51e-53	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPr
MDKIOEFL_03947	0.0	ptsG	2.7.1.199	-	G	ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MDKIOEFL_03948	6.87e-168	glcT	-	-	K	ko:K03480,ko:K03488	-	ko00000,ko03000	antiterminator
MDKIOEFL_03950	5.43e-229	ykvZ	-	-	K	-	-	-	Transcriptional regulator
MDKIOEFL_03952	2.74e-264	ykvY	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
MDKIOEFL_03953	3.99e-09	-	-	-	-	-	-	-	-
MDKIOEFL_03954	0.0	zosA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
MDKIOEFL_03955	5.79e-117	stoA	-	-	CO	-	-	-	thiol-disulfide
MDKIOEFL_03956	6.46e-302	ykvU	-	-	S	-	-	-	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MDKIOEFL_03957	5.26e-141	ykvT	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell Wall Hydrolase
MDKIOEFL_03958	2.6e-39	-	-	-	-	-	-	-	-
MDKIOEFL_03959	5.43e-35	ykvS	-	-	S	-	-	-	protein conserved in bacteria
MDKIOEFL_03960	2.67e-62	ykvR	-	-	S	-	-	-	Protein of unknown function (DUF3219)
MDKIOEFL_03961	1.75e-204	-	-	-	G	-	-	-	Glycosyl hydrolases family 18
MDKIOEFL_03962	7.56e-48	-	3.5.1.104	-	M	ko:K22278	-	ko00000,ko01000	LysM domain
MDKIOEFL_03963	3.51e-271	-	-	-	M	-	-	-	Glycosyl transferases group 1
MDKIOEFL_03964	7.68e-172	ykvO	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
MDKIOEFL_03965	1.22e-80	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
MDKIOEFL_03966	2.36e-125	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MDKIOEFL_03967	3.56e-179	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
MDKIOEFL_03968	6.96e-105	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	synthase
MDKIOEFL_03969	6.42e-161	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MDKIOEFL_03970	1.36e-226	ykvI	-	-	S	-	-	-	membrane
MDKIOEFL_03971	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
MDKIOEFL_03972	3.23e-178	motA	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
MDKIOEFL_03973	4.91e-170	motB	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
MDKIOEFL_03974	5.17e-99	ykvE	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
MDKIOEFL_03975	0.0	kinD	2.7.13.3	-	T	ko:K13532	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
MDKIOEFL_03976	5.84e-95	eag	-	-	-	-	-	-	-
MDKIOEFL_03978	8.82e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF1232)
MDKIOEFL_03979	3.03e-123	mtnD	1.13.11.53, 1.13.11.54	-	S	ko:K08967	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
MDKIOEFL_03980	1.84e-146	mtnB	4.2.1.109	-	E	ko:K08964	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
MDKIOEFL_03981	1.02e-174	mtnX	3.1.3.87	-	E	ko:K08966	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
MDKIOEFL_03982	9.72e-295	mtnW	5.3.2.5	-	G	ko:K08965	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
MDKIOEFL_03983	1.88e-293	mtnE	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MDKIOEFL_03984	1.15e-192	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MDKIOEFL_03985	2.37e-291	mtnK	2.7.1.100	-	F	ko:K00899	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
MDKIOEFL_03986	1.09e-251	mtnA	5.3.1.23	-	E	ko:K08963	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MDKIOEFL_03988	2.76e-115	ogt	2.1.1.63	-	L	ko:K00567,ko:K13531	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MDKIOEFL_03989	0.0	kinE	2.7.13.3	-	T	ko:K13533	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MDKIOEFL_03990	2.75e-243	ykrP	-	-	G	-	-	-	COG3594 Fucose 4-O-acetylase and related acetyltransferases
MDKIOEFL_03991	1.77e-28	ykzE	-	-	-	-	-	-	-
MDKIOEFL_03993	2.58e-310	ktrD	-	-	P	-	-	-	COG0168 Trk-type K transport systems, membrane components
MDKIOEFL_03994	3.97e-199	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
MDKIOEFL_03995	1.55e-159	ykrK	-	-	S	-	-	-	Domain of unknown function (DUF1836)
MDKIOEFL_03996	1.4e-36	sspD	-	-	S	ko:K06421	-	ko00000	small acid-soluble spore protein
MDKIOEFL_03997	9.93e-200	rsgI	-	-	S	-	-	-	Anti-sigma factor N-terminus
MDKIOEFL_03998	1.8e-167	sigI	-	-	K	ko:K03093	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MDKIOEFL_03999	4.63e-227	ykoY	-	-	P	-	-	-	COG0861 Membrane protein TerC, possibly involved in tellurium resistance
MDKIOEFL_04000	1.71e-143	ykoX	-	-	S	-	-	-	membrane-associated protein
MDKIOEFL_04001	0.0	ykoW	2.7.7.65	-	T	ko:K21023	ko02025,map02025	ko00000,ko00001,ko01000	Diguanylate cyclase
MDKIOEFL_04002	1.25e-204	ku	-	-	L	ko:K10979	ko03450,map03450	ko00000,ko00001,ko03400	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MDKIOEFL_04003	0.0	ligD	6.5.1.1	-	L	ko:K01971	ko03450,map03450	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA ligase
MDKIOEFL_04004	9.49e-238	ykoT	-	-	M	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
MDKIOEFL_04005	0.0	ykoS	-	-	-	-	-	-	-
MDKIOEFL_04006	8.43e-196	ykoQ	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
MDKIOEFL_04007	2.38e-127	ykoP	-	-	G	-	-	-	polysaccharide deacetylase
MDKIOEFL_04008	1.33e-278	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
MDKIOEFL_04009	9.83e-106	ykoM	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
MDKIOEFL_04010	3.04e-36	ykoL	-	-	-	-	-	-	-
MDKIOEFL_04011	1.63e-25	-	-	-	-	-	-	-	-
MDKIOEFL_04012	1.49e-70	tnrA	-	-	K	-	-	-	transcriptional
MDKIOEFL_04013	9.86e-300	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
MDKIOEFL_04015	1.45e-08	-	-	-	-	-	-	-	-
MDKIOEFL_04016	1.51e-110	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
MDKIOEFL_04017	3.35e-146	ykoI	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
MDKIOEFL_04018	7.7e-310	ykoH	-	-	T	-	-	-	Histidine kinase
MDKIOEFL_04019	4.55e-152	ykoG	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MDKIOEFL_04020	9.94e-142	ykoF	-	-	S	-	-	-	YKOF-related Family
MDKIOEFL_04021	1.39e-127	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
MDKIOEFL_04022	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MDKIOEFL_04023	8.95e-174	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
MDKIOEFL_04024	3.99e-193	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MDKIOEFL_04025	3.66e-226	isp	-	-	O	ko:K13275	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MDKIOEFL_04026	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MDKIOEFL_04027	3.29e-114	guaD	3.5.4.3	-	FJ	ko:K01487	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	COG0590 Cytosine adenosine deaminases
MDKIOEFL_04028	2.34e-93	ohrB	-	-	O	-	-	-	Organic hydroperoxide resistance protein
MDKIOEFL_04029	1.42e-97	ohrR	-	-	K	-	-	-	COG1846 Transcriptional regulators
MDKIOEFL_04030	2.39e-93	ohrA	-	-	O	-	-	-	Organic hydroperoxide resistance protein
MDKIOEFL_04031	1.32e-288	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MDKIOEFL_04032	4.3e-255	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MDKIOEFL_04033	1.66e-217	purU	3.5.1.10	-	F	ko:K01433	ko00630,ko00670,map00630,map00670	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
MDKIOEFL_04034	1.36e-66	ykkD	-	-	P	ko:K18925	-	ko00000,ko00002,ko02000	Multidrug resistance protein
MDKIOEFL_04035	1.27e-72	ykkC	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Multidrug resistance protein
MDKIOEFL_04036	1.2e-126	ykkB	-	-	J	-	-	-	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MDKIOEFL_04037	6.42e-128	ykkA	-	-	S	-	-	-	Protein of unknown function (DUF664)
MDKIOEFL_04038	3.95e-167	ykjA	-	-	S	-	-	-	Protein of unknown function (DUF421)
MDKIOEFL_04039	2.11e-16	-	-	-	-	-	-	-	-
MDKIOEFL_04040	1.26e-287	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MDKIOEFL_04041	1.55e-119	ykhA	-	-	I	-	-	-	Acyl-CoA hydrolase
MDKIOEFL_04042	1.78e-205	ykgA	-	-	E	-	-	-	Amidinotransferase
MDKIOEFL_04043	5.46e-259	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconolactonase
MDKIOEFL_04044	2.82e-235	ykfD	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MDKIOEFL_04045	4.7e-206	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MDKIOEFL_04046	1.33e-254	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
MDKIOEFL_04047	5.11e-220	ykfA	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
MDKIOEFL_04049	0.0	dppE	-	-	E	ko:K16199	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MDKIOEFL_04050	9.08e-235	dppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MDKIOEFL_04051	3.02e-224	dppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MDKIOEFL_04052	9.7e-204	dppB	-	-	P	ko:K16200	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MDKIOEFL_04053	1.4e-196	dppA	-	-	E	ko:K16203	-	ko00000,ko01000,ko01002	D-aminopeptidase
MDKIOEFL_04054	4.95e-180	proG	1.5.1.2	-	E	ko:K00286,ko:K02239	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko02044	Pyrroline-5-carboxylate reductase
MDKIOEFL_04055	8.96e-280	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MDKIOEFL_04057	2.21e-229	ykcC	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
MDKIOEFL_04058	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MDKIOEFL_04059	3.84e-231	ykcA	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
MDKIOEFL_04060	2.57e-309	steT	-	-	E	ko:K03294	-	ko00000	amino acid
MDKIOEFL_04061	1.85e-144	ykaA	-	-	P	ko:K07220	-	ko00000	COG1392 Phosphate transport regulator (distant homolog of PhoU)
MDKIOEFL_04062	4.42e-225	pit	-	-	P	ko:K03306	-	ko00000	phosphate transporter
MDKIOEFL_04063	1.19e-175	spoIISA	-	-	S	ko:K06388	-	ko00000	Toxin SpoIISA, type II toxin-antitoxin system
MDKIOEFL_04064	1.78e-31	spoIISB	-	-	S	ko:K06389	-	ko00000	Stage II sporulation protein SB
MDKIOEFL_04066	3.73e-208	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
MDKIOEFL_04067	8.12e-53	xhlB	-	-	S	-	-	-	SPP1 phage holin
MDKIOEFL_04068	2.21e-51	xhlA	-	-	S	-	-	-	Haemolysin XhlA
MDKIOEFL_04069	1.14e-193	xepA	-	-	-	-	-	-	-
MDKIOEFL_04070	6.35e-31	xkdX	-	-	-	-	-	-	-
MDKIOEFL_04071	2.13e-58	xkdW	-	-	S	-	-	-	XkdW protein
MDKIOEFL_04072	2.13e-218	-	-	-	-	-	-	-	-
MDKIOEFL_04073	1.49e-54	-	-	-	-	-	-	-	-
MDKIOEFL_04074	3.77e-133	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2313)
MDKIOEFL_04075	2.08e-242	-	-	-	S	-	-	-	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
MDKIOEFL_04076	1.89e-90	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
MDKIOEFL_04077	1.45e-51	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
MDKIOEFL_04078	2.31e-232	xkdQ	-	-	G	-	-	-	NLP P60 protein
MDKIOEFL_04079	2.1e-152	xkdP	-	-	S	-	-	-	Lysin motif
MDKIOEFL_04080	0.0	xkdO	-	-	L	-	-	-	Transglycosylase SLT domain
MDKIOEFL_04081	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group