ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
LPNANANF_00001 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
LPNANANF_00004 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LPNANANF_00005 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LPNANANF_00007 0.0 - - - Q ko:K15665 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LPNANANF_00008 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LPNANANF_00025 0.0 - - - C - - - Na+/H+ antiporter family
LPNANANF_00026 5.71e-171 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
LPNANANF_00027 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LPNANANF_00028 0.0 ygaK - - C - - - Berberine and berberine like
LPNANANF_00030 1.91e-292 oppA5 - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 PFAM extracellular solute-binding protein family 5
LPNANANF_00031 5.79e-179 - - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LPNANANF_00032 1.02e-160 - - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LPNANANF_00033 8.12e-172 oppD3 - - P ko:K02031 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LPNANANF_00034 1.63e-168 oppF9 - - E ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LPNANANF_00035 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
LPNANANF_00036 1.91e-233 - - - S ko:K07045 - ko00000 Amidohydrolase
LPNANANF_00037 1.83e-179 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
LPNANANF_00038 7.12e-229 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
LPNANANF_00039 1.17e-185 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
LPNANANF_00040 8.61e-273 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
LPNANANF_00041 1.18e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LPNANANF_00042 2.6e-106 ygaO - - - - - - -
LPNANANF_00043 9.41e-32 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
LPNANANF_00045 2.73e-147 yhzB - - S - - - B3/4 domain
LPNANANF_00046 8.45e-287 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LPNANANF_00047 5.12e-226 yhbB - - S - - - Putative amidase domain
LPNANANF_00048 4.84e-112 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
LPNANANF_00049 3.4e-141 yhbD - - K - - - Protein of unknown function (DUF4004)
LPNANANF_00050 1.21e-86 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
LPNANANF_00051 1.56e-91 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
LPNANANF_00052 1.23e-07 - - - - - - - -
LPNANANF_00053 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
LPNANANF_00054 2.06e-279 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
LPNANANF_00055 4.15e-98 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
LPNANANF_00056 1.54e-132 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
LPNANANF_00057 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
LPNANANF_00058 9.09e-129 wrbA 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
LPNANANF_00059 1.41e-72 yhcC - - - - - - -
LPNANANF_00060 3.76e-65 - - - - - - - -
LPNANANF_00061 2.33e-81 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
LPNANANF_00062 8.11e-159 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LPNANANF_00063 1.36e-214 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LPNANANF_00064 1.57e-209 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
LPNANANF_00065 7.28e-42 cspB - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
LPNANANF_00066 4.82e-189 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
LPNANANF_00067 1.71e-242 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
LPNANANF_00068 4.31e-292 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LPNANANF_00069 1.11e-79 yhcM - - - - - - -
LPNANANF_00070 2.69e-122 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LPNANANF_00071 2.74e-206 yhcP - - - - - - -
LPNANANF_00072 4.45e-151 yhcQ - - M - - - Spore coat protein
LPNANANF_00073 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
LPNANANF_00074 5.53e-138 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
LPNANANF_00075 7.59e-215 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
LPNANANF_00076 3.12e-91 yhcU - - S - - - Family of unknown function (DUF5365)
LPNANANF_00077 2.5e-90 yhcV - - S - - - COG0517 FOG CBS domain
LPNANANF_00078 3.41e-161 yhcW - - S ko:K07025 - ko00000 hydrolase
LPNANANF_00079 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
LPNANANF_00080 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LPNANANF_00081 5.16e-135 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
LPNANANF_00082 3.3e-198 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
LPNANANF_00083 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LPNANANF_00084 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LPNANANF_00085 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
LPNANANF_00086 7.5e-263 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
LPNANANF_00087 1.9e-144 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LPNANANF_00088 1.19e-116 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
LPNANANF_00089 6.98e-53 yhdB - - S - - - YhdB-like protein
LPNANANF_00090 2.42e-70 yhdC - - S - - - Protein of unknown function (DUF3889)
LPNANANF_00091 3.47e-296 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
LPNANANF_00092 1.32e-96 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
LPNANANF_00093 0.0 ygxB - - M - - - Conserved TM helix
LPNANANF_00094 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
LPNANANF_00095 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
LPNANANF_00096 3.73e-176 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
LPNANANF_00097 2.73e-207 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
LPNANANF_00098 4.69e-261 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
LPNANANF_00099 7.83e-206 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LPNANANF_00100 4.45e-316 yhdG - - E ko:K03294 - ko00000 amino acid
LPNANANF_00101 2.07e-267 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
LPNANANF_00102 8.62e-59 yhdK - - S - - - Sigma-M inhibitor protein
LPNANANF_00103 6.88e-257 yhdL - - S - - - Sigma factor regulator N-terminal
LPNANANF_00104 4.6e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LPNANANF_00105 1.86e-141 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
LPNANANF_00106 3.94e-307 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
LPNANANF_00107 1.19e-93 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
LPNANANF_00108 3.88e-284 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
LPNANANF_00109 6.41e-300 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LPNANANF_00110 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
LPNANANF_00111 2.9e-70 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LPNANANF_00112 4.77e-77 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LPNANANF_00113 1.56e-166 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
LPNANANF_00114 1.45e-08 yhdX - - S - - - Uncharacterized protein YhdX
LPNANANF_00115 1.11e-260 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
LPNANANF_00116 1.14e-177 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
LPNANANF_00117 9.86e-201 nodB1 - - G - - - deacetylase
LPNANANF_00118 2.41e-197 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
LPNANANF_00119 1e-113 pksA - - K - - - Transcriptional regulator
LPNANANF_00120 4.44e-123 ymcC - - S - - - Membrane
LPNANANF_00121 7.15e-110 - - - T - - - universal stress protein
LPNANANF_00123 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
LPNANANF_00124 0.0 yheH - - V ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
LPNANANF_00125 1.91e-140 yheG - - GM - - - NAD(P)H-binding
LPNANANF_00127 1.15e-39 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
LPNANANF_00128 2.12e-49 yheE - - S - - - Family of unknown function (DUF5342)
LPNANANF_00129 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
LPNANANF_00130 2.19e-272 yheC - - HJ - - - YheC/D like ATP-grasp
LPNANANF_00131 5.52e-264 yheB - - S - - - Belongs to the UPF0754 family
LPNANANF_00132 2.32e-70 yheA - - S - - - Belongs to the UPF0342 family
LPNANANF_00133 2.48e-258 yhaZ - - L - - - DNA alkylation repair enzyme
LPNANANF_00134 1.03e-205 yhaX - - S - - - haloacid dehalogenase-like hydrolase
LPNANANF_00135 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
LPNANANF_00136 0.0 - 1.14.13.59 - Q ko:K03897 ko00310,ko01120,map00310,map01120 ko00000,ko00001,ko01000 L-lysine 6-monooxygenase (NADPH-requiring)
LPNANANF_00137 1.41e-266 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
LPNANANF_00138 8.88e-112 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
LPNANANF_00140 2.89e-175 yhaR - - I - - - enoyl-CoA hydratase
LPNANANF_00141 5.99e-21 - - - S - - - YhzD-like protein
LPNANANF_00142 3.92e-215 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LPNANANF_00143 4.82e-277 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
LPNANANF_00144 1.83e-300 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
LPNANANF_00145 0.0 yhaN - - L - - - AAA domain
LPNANANF_00146 2.48e-226 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
LPNANANF_00147 8.23e-43 yhaL - - S - - - Sporulation protein YhaL
LPNANANF_00148 1.66e-184 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
LPNANANF_00149 1.29e-123 yhaK - - S - - - Putative zincin peptidase
LPNANANF_00150 1.2e-72 yhaI - - S - - - Protein of unknown function (DUF1878)
LPNANANF_00151 4.73e-146 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
LPNANANF_00152 4.74e-55 yhaH - - S - - - YtxH-like protein
LPNANANF_00153 2.55e-24 - - - - - - - -
LPNANANF_00154 5.58e-100 trpP - - S - - - Tryptophan transporter TrpP
LPNANANF_00155 1.69e-258 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LPNANANF_00156 4.79e-104 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
LPNANANF_00157 1.82e-174 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
LPNANANF_00158 4.51e-281 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
LPNANANF_00159 2.04e-160 ecsC - - S - - - EcsC protein family
LPNANANF_00160 1.25e-285 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
LPNANANF_00161 3.98e-311 yhfA - - C - - - membrane
LPNANANF_00162 2.98e-115 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
LPNANANF_00163 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
LPNANANF_00164 7.35e-259 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LPNANANF_00165 4.49e-232 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
LPNANANF_00166 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LPNANANF_00167 3.63e-130 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
LPNANANF_00168 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
LPNANANF_00169 3.43e-234 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LPNANANF_00171 3.65e-251 yhfE - - G - - - peptidase M42
LPNANANF_00172 3.36e-289 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LPNANANF_00173 1.99e-181 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
LPNANANF_00174 1.85e-241 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
LPNANANF_00175 4.27e-141 yhfK - - GM - - - NmrA-like family
LPNANANF_00176 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
LPNANANF_00177 7.96e-85 yhfM - - - - - - -
LPNANANF_00178 8.74e-299 yhfN - - O - - - Peptidase M48
LPNANANF_00179 9.1e-261 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
LPNANANF_00180 6.29e-193 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
LPNANANF_00181 6.03e-134 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
LPNANANF_00182 2.04e-252 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
LPNANANF_00183 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
LPNANANF_00184 7.56e-116 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
LPNANANF_00185 1.87e-275 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
LPNANANF_00186 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
LPNANANF_00187 1.35e-204 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LPNANANF_00188 9.48e-43 yhzC - - S - - - IDEAL
LPNANANF_00189 1.09e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
LPNANANF_00190 1.79e-88 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
LPNANANF_00191 3.61e-84 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
LPNANANF_00192 9.12e-70 - - - S - - - MepB protein
LPNANANF_00193 7.36e-162 yrpD - - S - - - Domain of unknown function, YrpD
LPNANANF_00194 1.23e-57 yhjA - - S - - - Excalibur calcium-binding domain
LPNANANF_00195 2.64e-63 - - - S - - - Belongs to the UPF0145 family
LPNANANF_00196 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LPNANANF_00197 1.37e-37 yhjC - - S - - - Protein of unknown function (DUF3311)
LPNANANF_00198 5.86e-79 yhjD - - - - - - -
LPNANANF_00199 2.23e-142 yhjE - - S - - - SNARE associated Golgi protein
LPNANANF_00200 6.7e-119 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
LPNANANF_00201 0.0 yhjG - - CH - - - FAD binding domain
LPNANANF_00202 8.11e-121 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
LPNANANF_00203 2.42e-262 yhjN - - S ko:K07120 - ko00000 membrane
LPNANANF_00204 2.64e-268 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
LPNANANF_00205 2.15e-139 - - - K - - - QacR-like protein, C-terminal region
LPNANANF_00206 1.79e-122 yhjR - - S - - - Rubrerythrin
LPNANANF_00207 1.48e-159 ydfS - - S - - - Protein of unknown function (DUF421)
LPNANANF_00208 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
LPNANANF_00209 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
LPNANANF_00210 4.7e-283 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
LPNANANF_00211 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
LPNANANF_00212 1.53e-66 yisB - - V - - - COG1403 Restriction endonuclease
LPNANANF_00213 6.66e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
LPNANANF_00214 1.67e-86 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
LPNANANF_00215 3e-33 gerPD - - S ko:K06302 - ko00000 Spore germination protein
LPNANANF_00216 8.51e-109 gerPC - - S ko:K06301 - ko00000 Spore germination protein
LPNANANF_00217 6.59e-48 gerPB - - S ko:K06300 - ko00000 cell differentiation
LPNANANF_00218 1.28e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
LPNANANF_00219 1.59e-11 yisI - - S - - - Spo0E like sporulation regulatory protein
LPNANANF_00220 8.91e-218 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
LPNANANF_00221 2.22e-78 yisL - - S - - - UPF0344 protein
LPNANANF_00222 4.56e-125 yisN - - S - - - Protein of unknown function (DUF2777)
LPNANANF_00223 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
LPNANANF_00224 1.27e-169 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
LPNANANF_00225 2.14e-312 yisQ - - V - - - Mate efflux family protein
LPNANANF_00226 1.58e-204 yisR - - K - - - Transcriptional regulator
LPNANANF_00227 2.87e-112 yisT - - S - - - DinB family
LPNANANF_00228 1.6e-103 yisX - - S - - - Pentapeptide repeats (9 copies)
LPNANANF_00229 3.78e-106 - - - S - - - Acetyltransferase (GNAT) domain
LPNANANF_00230 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
LPNANANF_00231 3.69e-78 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
LPNANANF_00232 1.59e-206 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
LPNANANF_00233 1.04e-219 - - - S ko:K07335 - ko00000 ABC transporter substrate-binding protein PnrA-like
LPNANANF_00234 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
LPNANANF_00235 2.54e-307 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
LPNANANF_00237 5.5e-203 yitS - - S - - - protein conserved in bacteria
LPNANANF_00238 4.62e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
LPNANANF_00239 1.51e-104 ipi - - S - - - Intracellular proteinase inhibitor
LPNANANF_00240 1.5e-36 - - - S - - - Protein of unknown function (DUF3813)
LPNANANF_00241 1.49e-11 - - - - - - - -
LPNANANF_00242 5.08e-197 - 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
LPNANANF_00243 1.06e-186 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
LPNANANF_00244 3.26e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
LPNANANF_00245 8.23e-106 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
LPNANANF_00246 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
LPNANANF_00247 2.79e-120 yitZ - - G - - - Major Facilitator Superfamily
LPNANANF_00248 3.02e-254 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LPNANANF_00249 1.48e-289 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LPNANANF_00250 2.02e-172 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
LPNANANF_00251 2.68e-275 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
LPNANANF_00252 4.86e-259 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
LPNANANF_00253 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
LPNANANF_00254 1.18e-224 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LPNANANF_00255 7.21e-39 yjzC - - S - - - YjzC-like protein
LPNANANF_00256 1.06e-32 yjzD - - S - - - Protein of unknown function (DUF2929)
LPNANANF_00257 1.83e-177 yjaU - - I - - - carboxylic ester hydrolase activity
LPNANANF_00258 1.18e-134 yjaV - - - - - - -
LPNANANF_00259 4.67e-213 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
LPNANANF_00260 6.46e-37 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
LPNANANF_00261 1.63e-43 yjzB - - - - - - -
LPNANANF_00262 3.78e-220 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LPNANANF_00263 3.86e-300 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LPNANANF_00264 7.48e-190 yjaZ - - O - - - Zn-dependent protease
LPNANANF_00265 8.37e-232 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LPNANANF_00266 7.23e-238 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LPNANANF_00267 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
LPNANANF_00268 5.76e-217 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LPNANANF_00269 1.67e-198 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LPNANANF_00270 5.28e-189 yjbA - - S - - - Belongs to the UPF0736 family
LPNANANF_00271 8.74e-235 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
LPNANANF_00272 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
LPNANANF_00273 1.46e-212 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LPNANANF_00274 2.07e-209 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LPNANANF_00275 1.5e-256 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LPNANANF_00276 8.93e-220 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LPNANANF_00277 1.37e-292 - - - S - - - Putative glycosyl hydrolase domain
LPNANANF_00278 4.4e-132 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LPNANANF_00279 2.47e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
LPNANANF_00280 3.23e-140 yjbE - - P - - - Integral membrane protein TerC family
LPNANANF_00281 9.78e-150 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
LPNANANF_00282 5.7e-282 coiA - - S ko:K06198 - ko00000 Competence protein
LPNANANF_00283 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
LPNANANF_00284 3.14e-27 - - - - - - - -
LPNANANF_00285 6.05e-220 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
LPNANANF_00286 7.06e-93 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
LPNANANF_00287 3.12e-152 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
LPNANANF_00288 9.97e-126 yjbK - - S - - - protein conserved in bacteria
LPNANANF_00289 2.03e-80 yjbL - - S - - - Belongs to the UPF0738 family
LPNANANF_00290 1.56e-139 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
LPNANANF_00291 2.07e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LPNANANF_00292 9.96e-213 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
LPNANANF_00293 3.05e-183 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
LPNANANF_00294 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
LPNANANF_00295 2.23e-176 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LPNANANF_00296 3.3e-138 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
LPNANANF_00297 2.17e-266 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
LPNANANF_00298 1.3e-40 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 Thiamine biosynthesis
LPNANANF_00299 1.81e-173 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
LPNANANF_00300 9.16e-240 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
LPNANANF_00301 4.3e-189 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
LPNANANF_00302 1.14e-178 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
LPNANANF_00303 3.38e-125 yjbX - - S - - - Spore coat protein
LPNANANF_00304 9.62e-105 cotZ - - S ko:K06344 - ko00000 Spore coat protein
LPNANANF_00305 1.96e-117 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
LPNANANF_00306 6.68e-103 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
LPNANANF_00307 1.98e-36 cotW - - - ko:K06341 - ko00000 -
LPNANANF_00308 7.11e-73 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
LPNANANF_00309 2.92e-73 yjcA - - S - - - Protein of unknown function (DUF1360)
LPNANANF_00312 5.69e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
LPNANANF_00313 2.57e-51 spoVIF - - S - - - Stage VI sporulation protein F
LPNANANF_00314 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
LPNANANF_00315 1.23e-48 - - - - - - - -
LPNANANF_00316 1.34e-177 blm 3.5.2.6 - S ko:K17837 ko01501,map01501 ko00000,ko00001,ko01000 Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
LPNANANF_00317 3.77e-159 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
LPNANANF_00318 2.48e-171 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
LPNANANF_00319 4.32e-48 - - - K - - - SpoVT / AbrB like domain
LPNANANF_00320 2.48e-96 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LPNANANF_00321 6.97e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
LPNANANF_00322 4.99e-164 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
LPNANANF_00323 3.93e-271 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
LPNANANF_00324 1.34e-278 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
LPNANANF_00326 1.74e-05 - - - L ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family
LPNANANF_00327 3e-75 - - - - - - - -
LPNANANF_00328 0.0 - - - S - - - Bacterial EndoU nuclease
LPNANANF_00331 5.66e-79 - - - E - - - Glyoxalase-like domain
LPNANANF_00332 1.35e-209 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
LPNANANF_00333 2.2e-61 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
LPNANANF_00334 0.0 yfjF - - EGP - - - Belongs to the major facilitator superfamily
LPNANANF_00335 1.75e-105 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
LPNANANF_00336 8.65e-278 yvfO 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
LPNANANF_00337 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
LPNANANF_00338 1.21e-241 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
LPNANANF_00339 1.9e-277 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LPNANANF_00340 0.0 lacE 2.7.1.207 - G ko:K02761,ko:K02787,ko:K02788 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LPNANANF_00341 8.91e-67 celC 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LPNANANF_00342 0.0 lacG 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LPNANANF_00343 1.39e-177 yulB - - K ko:K02530 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
LPNANANF_00344 6.88e-160 - - - S - - - Haloacid dehalogenase-like hydrolase
LPNANANF_00345 5.62e-45 - - - - - - - -
LPNANANF_00346 3.41e-68 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
LPNANANF_00347 1.01e-135 - - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
LPNANANF_00349 3.85e-31 yjfB - - S - - - Putative motility protein
LPNANANF_00350 1.48e-90 yjgA - - T - - - Protein of unknown function (DUF2809)
LPNANANF_00351 4.58e-128 yjgB - - S - - - Domain of unknown function (DUF4309)
LPNANANF_00352 0.0 - 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
LPNANANF_00353 7.36e-116 yjgD - - S - - - Protein of unknown function (DUF1641)
LPNANANF_00354 2.45e-286 yjiB 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
LPNANANF_00355 1.64e-283 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
LPNANANF_00356 1.73e-40 - - - - - - - -
LPNANANF_00357 4.58e-184 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
LPNANANF_00358 3.6e-158 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
LPNANANF_00359 5.33e-167 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 Belongs to the ABC transporter superfamily
LPNANANF_00360 4.11e-227 yjlA - - EG - - - Putative multidrug resistance efflux transporter
LPNANANF_00361 3.49e-118 yjlB - - S - - - Cupin domain
LPNANANF_00362 1.7e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
LPNANANF_00363 2.5e-279 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
LPNANANF_00364 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
LPNANANF_00365 0.0 - - - G ko:K03292 - ko00000 symporter YjmB
LPNANANF_00366 2.93e-234 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
LPNANANF_00367 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
LPNANANF_00368 0.0 uxaA 4.2.1.7 - G ko:K01685 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
LPNANANF_00369 3.21e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
LPNANANF_00370 8.38e-103 yjoA - - S - - - DinB family
LPNANANF_00371 1.55e-274 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
LPNANANF_00373 1.67e-221 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
LPNANANF_00374 9.51e-81 yjqA - - S - - - Bacterial PH domain
LPNANANF_00375 5.1e-140 yjqB - - S - - - phage-related replication protein
LPNANANF_00377 6.51e-145 xkdA - - E - - - IrrE N-terminal-like domain
LPNANANF_00378 6.52e-75 xre - - K - - - Helix-turn-helix XRE-family like proteins
LPNANANF_00380 5.93e-194 xkdC - - L - - - Bacterial dnaA protein
LPNANANF_00384 1.24e-109 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
LPNANANF_00385 2.04e-141 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
LPNANANF_00386 1.12e-261 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
LPNANANF_00387 4.94e-302 xkdE3 - - S - - - portal protein
LPNANANF_00388 8.8e-119 xkdF3 - - L - - - Putative phage serine protease XkdF
LPNANANF_00389 8.3e-203 xkdG - - S - - - Phage capsid family
LPNANANF_00390 1.26e-60 yqbG - - S - - - Protein of unknown function (DUF3199)
LPNANANF_00391 1.42e-56 - - - S - - - Domain of unknown function (DUF3599)
LPNANANF_00392 2.41e-77 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
LPNANANF_00393 8.64e-74 xkdJ - - - - - - -
LPNANANF_00394 1.57e-20 - - - - - - - -
LPNANANF_00395 2.31e-287 xkdK - - S - - - Phage tail sheath C-terminal domain
LPNANANF_00396 8.21e-97 xkdM - - S - - - Phage tail tube protein
LPNANANF_00397 7.28e-96 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
LPNANANF_00398 4.33e-27 - - - - - - - -
LPNANANF_00399 1.49e-277 xkdO - - L - - - Transglycosylase SLT domain
LPNANANF_00400 6.56e-145 xkdP - - S - - - Lysin motif
LPNANANF_00401 7.63e-206 xkdQ - - G - - - NLP P60 protein
LPNANANF_00402 2.51e-43 xkdR - - S - - - Protein of unknown function (DUF2577)
LPNANANF_00403 2.86e-76 xkdS - - S - - - Protein of unknown function (DUF2634)
LPNANANF_00404 4.38e-212 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
LPNANANF_00405 5.83e-112 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
LPNANANF_00406 1.27e-37 - - - - - - - -
LPNANANF_00407 8.48e-85 - - - - - - - -
LPNANANF_00409 3.25e-40 xkdX - - - - - - -
LPNANANF_00410 1.56e-178 xepA - - - - - - -
LPNANANF_00411 3.87e-51 xhlA - - S - - - Haemolysin XhlA
LPNANANF_00412 4.7e-52 xhlB - - S - - - SPP1 phage holin
LPNANANF_00413 2.02e-214 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
LPNANANF_00414 2.53e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
LPNANANF_00415 1.89e-172 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
LPNANANF_00416 7.07e-226 pit - - P ko:K03306 - ko00000 phosphate transporter
LPNANANF_00417 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
LPNANANF_00418 2.3e-312 steT - - E ko:K03294 - ko00000 amino acid
LPNANANF_00419 4.3e-228 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
LPNANANF_00420 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LPNANANF_00421 1.56e-229 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
LPNANANF_00423 5.06e-274 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LPNANANF_00424 0.0 yubD - - P - - - Major Facilitator Superfamily
LPNANANF_00426 1.46e-198 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
LPNANANF_00427 1.39e-204 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LPNANANF_00428 7.69e-226 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LPNANANF_00429 2.26e-243 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LPNANANF_00430 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
LPNANANF_00431 5.4e-224 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
LPNANANF_00432 4.48e-257 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
LPNANANF_00433 8.91e-217 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
LPNANANF_00434 2.31e-231 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LPNANANF_00435 1.98e-261 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
LPNANANF_00436 8.45e-204 ykgA - - E - - - Amidinotransferase
LPNANANF_00437 3.06e-120 ykhA - - I - - - Acyl-CoA hydrolase
LPNANANF_00438 7.43e-130 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
LPNANANF_00439 4.09e-69 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
LPNANANF_00440 1.04e-65 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
LPNANANF_00441 2.76e-216 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
LPNANANF_00442 1.77e-261 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LPNANANF_00443 1.95e-290 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LPNANANF_00444 6.87e-93 ohrA - - O - - - Organic hydroperoxide resistance protein
LPNANANF_00445 2.43e-111 ohrR - - K - - - COG1846 Transcriptional regulators
LPNANANF_00446 3.2e-91 ohrB - - O - - - Organic hydroperoxide resistance protein
LPNANANF_00447 6.7e-82 - - - D - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LPNANANF_00449 1.01e-274 - - - M - - - Glycosyl transferase family 2
LPNANANF_00450 1.75e-182 - - - M - - - PFAM Collagen triple helix repeat (20 copies)
LPNANANF_00451 5.66e-277 - - - EGP ko:K05820 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
LPNANANF_00452 3.86e-156 nsr - - T - - - COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
LPNANANF_00453 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LPNANANF_00454 5.2e-226 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
LPNANANF_00455 1.05e-188 yojH - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LPNANANF_00456 4.41e-169 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
LPNANANF_00457 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LPNANANF_00458 1.39e-127 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
LPNANANF_00459 2.19e-310 ydhD - - M - - - Glycosyl hydrolase
LPNANANF_00461 2.48e-309 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
LPNANANF_00462 1.23e-69 tnrA - - K - - - transcriptional
LPNANANF_00463 1.11e-23 - - - - - - - -
LPNANANF_00464 5.25e-37 ykoL - - - - - - -
LPNANANF_00465 5.46e-105 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
LPNANANF_00466 3.81e-129 ykoP - - G - - - polysaccharide deacetylase
LPNANANF_00467 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
LPNANANF_00468 3.42e-202 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
LPNANANF_00469 2.88e-131 ykoX - - S - - - membrane-associated protein
LPNANANF_00470 2.91e-173 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
LPNANANF_00471 6.02e-163 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LPNANANF_00472 8.34e-233 ykrI - - S - - - Anti-sigma factor N-terminus
LPNANANF_00473 2.33e-35 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
LPNANANF_00474 5.64e-162 ykrK - - S - - - Domain of unknown function (DUF1836)
LPNANANF_00475 5.22e-199 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
LPNANANF_00476 1.62e-309 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
LPNANANF_00477 2.11e-148 - - - S - - - Protein of unknown function (DUF421)
LPNANANF_00478 3.07e-32 ykzE - - - - - - -
LPNANANF_00479 2.16e-240 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
LPNANANF_00480 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LPNANANF_00481 2.27e-114 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LPNANANF_00483 4.44e-251 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
LPNANANF_00484 2.44e-287 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
LPNANANF_00485 2.72e-191 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
LPNANANF_00486 1.48e-290 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
LPNANANF_00487 3.06e-286 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
LPNANANF_00488 1.34e-174 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
LPNANANF_00489 5.5e-148 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
LPNANANF_00490 5.03e-122 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
LPNANANF_00492 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
LPNANANF_00493 3.91e-100 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
LPNANANF_00494 4.04e-169 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
LPNANANF_00495 4.74e-176 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
LPNANANF_00496 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
LPNANANF_00497 1e-227 ykvI - - S - - - membrane
LPNANANF_00498 1.61e-254 - - - - - - - -
LPNANANF_00499 2.72e-162 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LPNANANF_00500 6.25e-103 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
LPNANANF_00501 1.76e-179 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
LPNANANF_00502 2.56e-124 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LPNANANF_00504 2.54e-77 ykvN - - K - - - Transcriptional regulator
LPNANANF_00505 2.57e-170 ykvO - - IQ - - - Enoyl-(Acyl carrier protein) reductase
LPNANANF_00506 9.98e-58 ykvR - - S - - - Protein of unknown function (DUF3219)
LPNANANF_00507 5.43e-35 ykvS - - S - - - protein conserved in bacteria
LPNANANF_00508 4.16e-38 - - - - - - - -
LPNANANF_00509 7.21e-143 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
LPNANANF_00510 2.66e-306 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LPNANANF_00511 8.57e-114 stoA - - CO - - - thiol-disulfide
LPNANANF_00512 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
LPNANANF_00513 1.16e-263 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
LPNANANF_00515 4.1e-224 ykvZ - - K - - - Transcriptional regulator
LPNANANF_00516 4.61e-198 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
LPNANANF_00517 0.0 ptsG 2.7.1.199 - G ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LPNANANF_00518 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
LPNANANF_00519 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LPNANANF_00520 3.63e-50 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
LPNANANF_00521 3.53e-256 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
LPNANANF_00522 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
LPNANANF_00523 6.67e-202 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
LPNANANF_00524 1.46e-168 ykwD - - J - - - protein with SCP PR1 domains
LPNANANF_00525 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
LPNANANF_00526 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LPNANANF_00527 1.62e-275 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
LPNANANF_00528 6.38e-15 - - - - - - - -
LPNANANF_00529 6.46e-212 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
LPNANANF_00530 5.07e-108 ykyB - - S - - - YkyB-like protein
LPNANANF_00531 4.6e-308 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
LPNANANF_00532 2.55e-116 ykuD - - S - - - protein conserved in bacteria
LPNANANF_00533 1.82e-197 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
LPNANANF_00534 6.12e-181 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LPNANANF_00536 2.21e-296 ykuI - - T - - - Diguanylate phosphodiesterase
LPNANANF_00537 3.63e-50 ykuJ - - S - - - protein conserved in bacteria
LPNANANF_00538 4.35e-120 ykuK - - S ko:K09776 - ko00000 Ribonuclease H-like
LPNANANF_00539 3.09e-35 ykzF - - S - - - Antirepressor AbbA
LPNANANF_00540 8.55e-99 ykuL - - S - - - CBS domain
LPNANANF_00541 1.32e-215 ccpC - - K - - - Transcriptional regulator
LPNANANF_00542 1.5e-115 ykuN - - C ko:K03839 - ko00000 Flavodoxin
LPNANANF_00543 1.37e-219 ykuO - - - - - - -
LPNANANF_00544 7.53e-104 fld - - C ko:K03839 - ko00000 Flavodoxin
LPNANANF_00545 2.89e-129 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
LPNANANF_00546 3.96e-276 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
LPNANANF_00547 2.15e-52 ykuS - - S - - - Belongs to the UPF0180 family
LPNANANF_00548 3.48e-178 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
LPNANANF_00549 3.87e-102 ykuV - - CO - - - thiol-disulfide
LPNANANF_00550 3.04e-126 rok - - K - - - Repressor of ComK
LPNANANF_00551 3.59e-218 yknT - - - ko:K06437 - ko00000 -
LPNANANF_00552 3.33e-140 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
LPNANANF_00553 1.71e-241 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
LPNANANF_00554 3.38e-310 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
LPNANANF_00555 4.56e-122 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
LPNANANF_00556 7.17e-109 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
LPNANANF_00557 1.7e-45 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LPNANANF_00558 3.27e-140 yknW - - S - - - Yip1 domain
LPNANANF_00559 1.15e-245 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LPNANANF_00560 2.38e-157 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LPNANANF_00561 4.23e-269 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
LPNANANF_00562 9.28e-170 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
LPNANANF_00563 7.87e-213 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
LPNANANF_00564 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
LPNANANF_00565 2.55e-136 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
LPNANANF_00566 1.28e-50 ykoA - - - - - - -
LPNANANF_00567 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
LPNANANF_00568 1.47e-212 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LPNANANF_00569 4.88e-302 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
LPNANANF_00570 4.47e-18 - - - S - - - Uncharacterized protein YkpC
LPNANANF_00571 3.72e-235 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
LPNANANF_00572 6.37e-60 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
LPNANANF_00573 3.4e-312 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
LPNANANF_00574 1.51e-196 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
LPNANANF_00575 9.71e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
LPNANANF_00576 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LPNANANF_00577 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LPNANANF_00578 1.28e-41 ykzG - - S - - - Belongs to the UPF0356 family
LPNANANF_00579 8.73e-187 ykrA - - S - - - hydrolases of the HAD superfamily
LPNANANF_00580 1.14e-130 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LPNANANF_00581 1.08e-06 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
LPNANANF_00582 1.32e-132 ykyA - - L - - - Putative cell-wall binding lipoprotein
LPNANANF_00583 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
LPNANANF_00584 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
LPNANANF_00585 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 polyketide synthase
LPNANANF_00586 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
LPNANANF_00587 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
LPNANANF_00588 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
LPNANANF_00589 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
LPNANANF_00590 0.0 - - - IQ - - - Phosphopantetheine attachment site
LPNANANF_00591 1.12e-265 - - - V - - - Beta-lactamase
LPNANANF_00592 6.68e-262 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
LPNANANF_00593 1.01e-226 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LPNANANF_00594 2.08e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LPNANANF_00595 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
LPNANANF_00596 7.97e-59 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
LPNANANF_00597 3.29e-191 pdaA_2 3.5.1.104 - G ko:K01567,ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
LPNANANF_00598 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
LPNANANF_00599 1.83e-54 yktA - - S - - - Belongs to the UPF0223 family
LPNANANF_00600 3.32e-154 yktB - - S - - - Belongs to the UPF0637 family
LPNANANF_00601 3.33e-33 ykzI - - - - - - -
LPNANANF_00602 2.33e-195 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
LPNANANF_00603 1.07e-107 ykzC - - S - - - Acetyltransferase (GNAT) family
LPNANANF_00604 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
LPNANANF_00605 1.22e-242 ylaA - - - - - - -
LPNANANF_00606 5.38e-61 ylaB - - - - - - -
LPNANANF_00607 8.94e-117 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LPNANANF_00609 5.69e-62 ylaE - - - - - - -
LPNANANF_00610 5.62e-33 - - - S - - - Family of unknown function (DUF5325)
LPNANANF_00611 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
LPNANANF_00612 2.44e-65 - - - S - - - YlaH-like protein
LPNANANF_00613 6.78e-46 ylaI - - S - - - protein conserved in bacteria
LPNANANF_00614 5.45e-138 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LPNANANF_00615 2.7e-313 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
LPNANANF_00616 3.53e-110 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LPNANANF_00617 5.18e-221 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
LPNANANF_00618 1.99e-58 ylaN - - S - - - Belongs to the UPF0358 family
LPNANANF_00619 3.49e-271 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
LPNANANF_00620 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LPNANANF_00621 3.47e-214 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
LPNANANF_00622 2.07e-209 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
LPNANANF_00623 6.83e-252 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
LPNANANF_00624 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LPNANANF_00625 5.92e-142 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
LPNANANF_00626 3.53e-69 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
LPNANANF_00627 1.46e-211 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
LPNANANF_00628 4.12e-79 ylbA - - S - - - YugN-like family
LPNANANF_00629 9.59e-96 ylbB - - T - - - COG0517 FOG CBS domain
LPNANANF_00630 1.89e-253 ylbC - - S - - - protein with SCP PR1 domains
LPNANANF_00631 5.96e-87 ylbD - - S - - - Putative coat protein
LPNANANF_00632 1.73e-48 ylbE - - S - - - YlbE-like protein
LPNANANF_00633 3.33e-97 ylbF - - S - - - Belongs to the UPF0342 family
LPNANANF_00634 3.94e-57 ylbG - - S - - - UPF0298 protein
LPNANANF_00636 2.47e-125 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
LPNANANF_00637 1.38e-108 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LPNANANF_00638 2.39e-276 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
LPNANANF_00639 2.48e-178 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
LPNANANF_00640 8.8e-240 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
LPNANANF_00641 3.68e-295 ylbM - - S - - - Belongs to the UPF0348 family
LPNANANF_00642 3.3e-115 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
LPNANANF_00643 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
LPNANANF_00644 3.13e-111 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
LPNANANF_00645 1.14e-116 ylbP - - K - - - n-acetyltransferase
LPNANANF_00646 2.79e-209 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LPNANANF_00647 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
LPNANANF_00648 1.78e-101 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
LPNANANF_00649 8.23e-219 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
LPNANANF_00650 2.4e-68 ftsL - - D - - - Essential cell division protein
LPNANANF_00651 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
LPNANANF_00652 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
LPNANANF_00653 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LPNANANF_00654 7.04e-222 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LPNANANF_00655 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LPNANANF_00656 2.7e-236 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
LPNANANF_00657 2.7e-257 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LPNANANF_00658 9.58e-214 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
LPNANANF_00659 2.67e-179 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
LPNANANF_00660 4.51e-298 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
LPNANANF_00661 2.61e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LPNANANF_00662 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
LPNANANF_00663 2.75e-216 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
LPNANANF_00664 7.35e-161 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LPNANANF_00665 9.33e-179 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LPNANANF_00666 1.97e-187 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
LPNANANF_00667 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
LPNANANF_00668 7.13e-52 ylmC - - S - - - sporulation protein
LPNANANF_00669 1.16e-206 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
LPNANANF_00670 1.23e-159 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LPNANANF_00671 4.61e-85 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
LPNANANF_00672 5.12e-56 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
LPNANANF_00673 3.54e-181 ylmH - - S - - - conserved protein, contains S4-like domain
LPNANANF_00674 1.85e-99 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
LPNANANF_00675 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LPNANANF_00676 4.22e-83 ylyA - - T - - - COG1734 DnaK suppressor protein
LPNANANF_00677 1.24e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LPNANANF_00678 5.35e-216 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
LPNANANF_00679 2.21e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LPNANANF_00680 1.33e-294 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
LPNANANF_00681 1.47e-213 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
LPNANANF_00682 6.34e-314 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
LPNANANF_00683 3.09e-268 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
LPNANANF_00684 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
LPNANANF_00685 5.87e-180 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
LPNANANF_00686 4.97e-220 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
LPNANANF_00687 1.01e-160 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
LPNANANF_00688 1.49e-147 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LPNANANF_00690 9.88e-181 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
LPNANANF_00691 2.45e-228 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
LPNANANF_00692 2.15e-284 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
LPNANANF_00693 6.76e-143 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
LPNANANF_00694 2.4e-184 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
LPNANANF_00695 1.69e-186 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
LPNANANF_00696 3.48e-103 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
LPNANANF_00697 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
LPNANANF_00698 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
LPNANANF_00699 2.14e-198 yloC - - S - - - stress-induced protein
LPNANANF_00700 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
LPNANANF_00701 4.91e-144 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
LPNANANF_00702 2.53e-38 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
LPNANANF_00703 2.54e-286 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LPNANANF_00704 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LPNANANF_00705 2.89e-110 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LPNANANF_00706 3.75e-221 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LPNANANF_00707 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LPNANANF_00708 1.52e-263 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
LPNANANF_00709 1.43e-177 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
LPNANANF_00710 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
LPNANANF_00711 2.53e-210 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
LPNANANF_00712 1.69e-150 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
LPNANANF_00713 4.34e-152 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
LPNANANF_00714 3.49e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
LPNANANF_00715 3.65e-78 yloU - - S - - - protein conserved in bacteria
LPNANANF_00716 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
LPNANANF_00717 4.15e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
LPNANANF_00718 2.4e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
LPNANANF_00719 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LPNANANF_00720 1.26e-120 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
LPNANANF_00721 3.14e-229 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
LPNANANF_00722 3.76e-218 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
LPNANANF_00723 5.81e-166 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
LPNANANF_00724 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
LPNANANF_00725 1.23e-173 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
LPNANANF_00726 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
LPNANANF_00727 2.19e-223 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
LPNANANF_00728 1.06e-182 - - - S - - - Phosphotransferase enzyme family
LPNANANF_00729 1.97e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LPNANANF_00730 1.47e-303 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LPNANANF_00731 3.23e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
LPNANANF_00732 4.9e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
LPNANANF_00733 3.41e-80 ylqD - - S - - - YlqD protein
LPNANANF_00734 1.51e-121 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LPNANANF_00735 2.7e-174 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
LPNANANF_00736 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
LPNANANF_00737 5.09e-203 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LPNANANF_00738 8.29e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LPNANANF_00739 0.0 ylqG - - - - - - -
LPNANANF_00740 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
LPNANANF_00741 2.02e-270 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
LPNANANF_00742 7.59e-214 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LPNANANF_00743 3.11e-217 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
LPNANANF_00744 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LPNANANF_00745 2.22e-313 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LPNANANF_00746 6.29e-220 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
LPNANANF_00747 7.38e-121 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LPNANANF_00748 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LPNANANF_00749 2.77e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LPNANANF_00750 2.8e-84 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
LPNANANF_00751 8.81e-98 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
LPNANANF_00752 1.51e-50 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
LPNANANF_00753 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
LPNANANF_00754 2.48e-229 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
LPNANANF_00755 7.19e-125 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
LPNANANF_00756 5.19e-309 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
LPNANANF_00757 8.85e-92 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
LPNANANF_00758 6.56e-87 ylxF - - S - - - MgtE intracellular N domain
LPNANANF_00759 5.2e-261 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
LPNANANF_00760 8.9e-96 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
LPNANANF_00761 6.57e-178 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
LPNANANF_00762 1.05e-77 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
LPNANANF_00763 5.43e-230 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
LPNANANF_00764 4.21e-248 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LPNANANF_00765 2.12e-77 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
LPNANANF_00766 9.34e-144 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
LPNANANF_00767 6.02e-142 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
LPNANANF_00768 3.15e-51 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
LPNANANF_00769 1.35e-166 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
LPNANANF_00770 1.46e-241 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LPNANANF_00771 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LPNANANF_00772 6.52e-249 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
LPNANANF_00773 2.7e-201 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
LPNANANF_00774 4.97e-249 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
LPNANANF_00775 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
LPNANANF_00776 2.49e-105 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
LPNANANF_00777 3.42e-142 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
LPNANANF_00778 2.86e-113 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
LPNANANF_00779 3.96e-177 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LPNANANF_00780 5.85e-94 ylxL - - - - - - -
LPNANANF_00781 7.07e-167 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
LPNANANF_00782 1.63e-200 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LPNANANF_00783 7.09e-164 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
LPNANANF_00784 1.94e-118 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
LPNANANF_00785 7.76e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LPNANANF_00786 3.8e-179 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
LPNANANF_00787 4.26e-271 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
LPNANANF_00788 1.15e-296 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
LPNANANF_00789 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
LPNANANF_00790 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LPNANANF_00791 5.66e-106 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
LPNANANF_00792 4.04e-264 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
LPNANANF_00793 6.76e-56 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
LPNANANF_00794 6.16e-63 ylxQ - - J - - - ribosomal protein
LPNANANF_00795 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LPNANANF_00796 3.88e-60 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
LPNANANF_00797 1.03e-73 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LPNANANF_00798 3.64e-221 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LPNANANF_00799 2.6e-232 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
LPNANANF_00800 4.12e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LPNANANF_00801 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
LPNANANF_00802 1.02e-232 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
LPNANANF_00803 3.42e-298 mlpA - - S - - - Belongs to the peptidase M16 family
LPNANANF_00804 2.17e-56 ymxH - - S - - - YlmC YmxH family
LPNANANF_00805 7.79e-205 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
LPNANANF_00806 4.75e-138 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
LPNANANF_00807 5.8e-248 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LPNANANF_00808 2e-282 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
LPNANANF_00809 7.2e-202 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LPNANANF_00810 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LPNANANF_00811 2.27e-166 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
LPNANANF_00812 6.32e-42 - - - S - - - YlzJ-like protein
LPNANANF_00813 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
LPNANANF_00814 4.48e-172 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
LPNANANF_00815 3.16e-296 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
LPNANANF_00816 9.88e-100 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
LPNANANF_00817 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
LPNANANF_00818 3.22e-306 albE - - S - - - Peptidase M16
LPNANANF_00819 4.1e-310 ymfH - - S - - - zinc protease
LPNANANF_00820 2.37e-163 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
LPNANANF_00821 6.23e-56 ymfJ - - S - - - Protein of unknown function (DUF3243)
LPNANANF_00822 3.14e-183 ymfK - - S - - - Protein of unknown function (DUF3388)
LPNANANF_00823 5.76e-177 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
LPNANANF_00824 9.58e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LPNANANF_00825 8.97e-292 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
LPNANANF_00826 3.06e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LPNANANF_00827 5.23e-277 pbpX - - V - - - Beta-lactamase
LPNANANF_00828 2.91e-308 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
LPNANANF_00829 3.72e-196 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
LPNANANF_00830 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
LPNANANF_00831 1.01e-251 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
LPNANANF_00832 4.29e-275 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
LPNANANF_00833 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LPNANANF_00834 2.11e-88 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
LPNANANF_00835 7.09e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
LPNANANF_00836 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LPNANANF_00837 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LPNANANF_00839 1.36e-164 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
LPNANANF_00840 6.71e-207 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
LPNANANF_00841 2.6e-233 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
LPNANANF_00842 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
LPNANANF_00843 3.05e-48 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
LPNANANF_00844 4.24e-308 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
LPNANANF_00845 2.4e-184 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
LPNANANF_00846 3.42e-180 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
LPNANANF_00847 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
LPNANANF_00848 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
LPNANANF_00849 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
LPNANANF_00850 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
LPNANANF_00851 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
LPNANANF_00852 1.38e-293 cypA 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
LPNANANF_00853 4.27e-102 nucB - - M - - - Deoxyribonuclease NucA/NucB
LPNANANF_00854 1.28e-152 yoaK - - S - - - Membrane
LPNANANF_00855 2.78e-82 ymzB - - - - - - -
LPNANANF_00856 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
LPNANANF_00857 1.51e-06 - - - - - - - -
LPNANANF_00858 3.13e-160 ymaC - - S - - - Replication protein
LPNANANF_00859 9.92e-104 ymaD - - O - - - redox protein, regulator of disulfide bond formation
LPNANANF_00860 7.46e-72 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
LPNANANF_00861 1.82e-63 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
LPNANANF_00863 2.43e-76 ymaF - - S - - - YmaF family
LPNANANF_00864 3.11e-220 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LPNANANF_00865 9e-46 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
LPNANANF_00866 6e-59 - - - - - - - -
LPNANANF_00867 9.42e-29 ymzA - - - - - - -
LPNANANF_00868 1.61e-88 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
LPNANANF_00869 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LPNANANF_00870 5.77e-244 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LPNANANF_00871 1.29e-140 ymaB - - S - - - MutT family
LPNANANF_00872 1.86e-149 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
LPNANANF_00873 8.99e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
LPNANANF_00874 1.1e-294 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LPNANANF_00875 4.1e-311 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
LPNANANF_00876 4.39e-88 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
LPNANANF_00877 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
LPNANANF_00881 8.98e-317 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
LPNANANF_00882 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
LPNANANF_00883 2.22e-278 xylR - - GK - - - ROK family
LPNANANF_00884 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
LPNANANF_00885 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
LPNANANF_00886 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
LPNANANF_00890 2.21e-27 - - - - - - - -
LPNANANF_00891 3.61e-115 yobV - - K - - - WYL domain
LPNANANF_00892 1.65e-87 dinB - - S - - - DinB family
LPNANANF_00893 2.52e-238 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
LPNANANF_00894 4.61e-22 - - - S - - - Bacterial transferase hexapeptide (six repeats)
LPNANANF_00895 2.4e-42 - - - S - - - Bacterial transferase hexapeptide (six repeats)
LPNANANF_00897 6.73e-23 - - - - - - - -
LPNANANF_00898 3.3e-06 ywlA - - S - - - Uncharacterised protein family (UPF0715)
LPNANANF_00899 6.67e-189 yoaP - - K - - - YoaP-like
LPNANANF_00900 2.22e-126 - - - J - - - Acetyltransferase (GNAT) domain
LPNANANF_00902 8.83e-31 - - - - - - - -
LPNANANF_00903 4.83e-33 - - - - - - - -
LPNANANF_00905 3.74e-149 - - - S - - - Domain of unknown function (DUF3885)
LPNANANF_00906 1.14e-255 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LPNANANF_00907 1.65e-152 - - AA10,CBM73 S ko:K03933 - ko00000 Pfam:Chitin_bind_3
LPNANANF_00908 9.28e-07 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
LPNANANF_00909 6.37e-125 yvgO - - - - - - -
LPNANANF_00911 0.0 yobO - - M - - - Pectate lyase superfamily protein
LPNANANF_00912 6.07e-102 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
LPNANANF_00913 8.27e-184 yndL - - S - - - Replication protein
LPNANANF_00914 1.74e-11 - - - - - - - -
LPNANANF_00915 1.04e-183 - - - O - - - COG0330 Membrane protease subunits, stomatin prohibitin homologs
LPNANANF_00916 3.2e-95 yndM - - S - - - Protein of unknown function (DUF2512)
LPNANANF_00918 7.8e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LPNANANF_00919 4.1e-67 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
LPNANANF_00920 3.02e-144 yneB - - L - - - resolvase
LPNANANF_00921 2.33e-43 ynzC - - S - - - UPF0291 protein
LPNANANF_00922 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LPNANANF_00923 1.08e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
LPNANANF_00924 6.2e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
LPNANANF_00925 1.97e-33 ynzD - - S - - - Spo0E like sporulation regulatory protein
LPNANANF_00926 4.47e-164 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
LPNANANF_00927 2.47e-76 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
LPNANANF_00928 2.27e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
LPNANANF_00929 1.14e-96 yneK - - S - - - Protein of unknown function (DUF2621)
LPNANANF_00930 5.77e-81 cotM - - O ko:K06335 - ko00000 Spore coat protein
LPNANANF_00931 1.97e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
LPNANANF_00932 6.2e-22 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
LPNANANF_00933 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LPNANANF_00934 1.41e-119 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LPNANANF_00936 1.48e-45 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
LPNANANF_00937 2.94e-97 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
LPNANANF_00938 7.79e-70 yneQ - - - - - - -
LPNANANF_00939 3.8e-66 yneR - - S - - - Belongs to the HesB IscA family
LPNANANF_00940 5.25e-120 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
LPNANANF_00941 9.94e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
LPNANANF_00942 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LPNANANF_00943 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LPNANANF_00944 5.42e-20 - - - - - - - -
LPNANANF_00945 1.82e-63 ynfC - - - - - - -
LPNANANF_00946 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
LPNANANF_00947 2.22e-231 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
LPNANANF_00948 1.47e-242 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
LPNANANF_00949 1.24e-145 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
LPNANANF_00950 1.68e-272 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
LPNANANF_00951 3.03e-193 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
LPNANANF_00952 1.01e-230 regR - - K ko:K02525 - ko00000,ko03000 transcriptional
LPNANANF_00953 1.07e-284 exuT - - G ko:K08191,ko:K08194 - ko00000,ko02000 Sugar (and other) transporter
LPNANANF_00954 6.69e-133 yndG - - S - - - DoxX-like family
LPNANANF_00955 1.11e-99 - - - S - - - Domain of unknown function (DUF4166)
LPNANANF_00956 1.85e-237 yndJ - - S - - - YndJ-like protein
LPNANANF_00957 2.76e-58 yndJ - - S - - - YndJ-like protein
LPNANANF_00960 9.04e-274 - - - S - - - Platelet-activating factor acetylhydrolase, isoform II
LPNANANF_00962 4.65e-295 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
LPNANANF_00963 7.08e-68 yvlA - - S - - - Domain of unknown function (DUF4870)
LPNANANF_00964 2.68e-309 - - - T - - - Histidine kinase
LPNANANF_00965 7.64e-164 - - - T - - - Transcriptional regulatory protein, C terminal
LPNANANF_00966 1.97e-316 ynfF 3.2.1.136 GH5 G ko:K15924 - ko00000,ko01000 Glycosyl hydrolase family 30 beta sandwich domain
LPNANANF_00967 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
LPNANANF_00968 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LPNANANF_00969 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LPNANANF_00970 0.0 nrsA - - Q ko:K15661 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LPNANANF_00971 4.96e-290 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
LPNANANF_00972 2.89e-178 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
LPNANANF_00973 4.5e-157 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
LPNANANF_00974 1.04e-160 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LPNANANF_00975 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
LPNANANF_00976 7.54e-284 bioI 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
LPNANANF_00977 6.5e-246 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LPNANANF_00978 7.15e-165 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LPNANANF_00979 9.3e-272 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
LPNANANF_00980 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
LPNANANF_00981 2.91e-182 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
LPNANANF_00982 3.48e-95 yngA - - S - - - membrane
LPNANANF_00983 2.63e-208 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
LPNANANF_00984 5.33e-135 yngC - - S - - - SNARE associated Golgi protein
LPNANANF_00985 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
LPNANANF_00986 6.8e-176 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
LPNANANF_00987 6.01e-215 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
LPNANANF_00988 2.77e-41 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
LPNANANF_00989 0.0 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
LPNANANF_00990 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
LPNANANF_00991 1.53e-267 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
LPNANANF_00992 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
LPNANANF_00993 1.38e-84 yngL - - S - - - Protein of unknown function (DUF1360)
LPNANANF_00994 0.0 - - - Q ko:K15656,ko:K15668 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 D-alanine [D-alanyl carrier protein] ligase activity
LPNANANF_00995 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LPNANANF_00996 2.02e-234 yaaC - - S - - - YaaC-like Protein
LPNANANF_00997 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
LPNANANF_00998 0.0 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
LPNANANF_00999 1.29e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
LPNANANF_01000 2.86e-139 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
LPNANANF_01001 1.59e-285 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LPNANANF_01002 9.81e-260 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
LPNANANF_01004 7.51e-159 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
LPNANANF_01005 1.16e-148 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
LPNANANF_01006 3.03e-279 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
LPNANANF_01007 2.9e-128 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
LPNANANF_01008 2.48e-111 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
LPNANANF_01009 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LPNANANF_01010 9.8e-52 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LPNANANF_01011 8.53e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LPNANANF_01012 5.4e-43 yaaL - - S - - - Protein of unknown function (DUF2508)
LPNANANF_01013 6.44e-50 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
LPNANANF_01015 2.78e-168 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
LPNANANF_01016 3.2e-313 - 6.1.3.1, 6.2.1.3, 6.2.1.34 - IQ ko:K00666,ko:K01897,ko:K12508,ko:K22319 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
LPNANANF_01019 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
LPNANANF_01020 5.05e-121 nusG1 - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
LPNANANF_01021 6.48e-211 - - - K - - - LysR substrate binding domain
LPNANANF_01022 5.29e-65 - - - S - - - GlpM protein
LPNANANF_01023 1.27e-247 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
LPNANANF_01024 1.57e-189 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
LPNANANF_01025 2.77e-220 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
LPNANANF_01026 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LPNANANF_01027 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LPNANANF_01028 1.57e-300 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LPNANANF_01029 4.55e-35 yqzJ - - - - - - -
LPNANANF_01030 3.25e-188 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LPNANANF_01031 3.04e-258 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
LPNANANF_01032 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
LPNANANF_01033 3.82e-95 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
LPNANANF_01035 9.08e-124 yqjB - - S - - - protein conserved in bacteria
LPNANANF_01036 2.65e-218 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
LPNANANF_01037 6.07e-165 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
LPNANANF_01038 1.04e-141 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
LPNANANF_01039 1.37e-173 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
LPNANANF_01040 4.83e-99 yqiW - - S - - - Belongs to the UPF0403 family
LPNANANF_01041 4.26e-219 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
LPNANANF_01042 2.53e-284 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LPNANANF_01043 1.7e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LPNANANF_01044 3.08e-219 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
LPNANANF_01045 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
LPNANANF_01046 4.9e-263 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
LPNANANF_01047 2.61e-260 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
LPNANANF_01048 6.8e-195 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
LPNANANF_01049 0.0 bkdR - - KT - - - Transcriptional regulator
LPNANANF_01050 6.25e-47 yqzF - - S - - - Protein of unknown function (DUF2627)
LPNANANF_01051 1.63e-204 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LPNANANF_01052 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
LPNANANF_01053 7.23e-263 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
LPNANANF_01054 5.9e-259 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
LPNANANF_01055 5.06e-199 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
LPNANANF_01056 5.6e-272 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
LPNANANF_01057 1.1e-174 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
LPNANANF_01058 1.39e-136 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
LPNANANF_01060 1.96e-131 - - - P - - - Probably functions as a manganese efflux pump
LPNANANF_01061 1.15e-145 - - - K - - - Protein of unknown function (DUF1232)
LPNANANF_01063 1.37e-273 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
LPNANANF_01066 1.01e-274 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LPNANANF_01067 6.11e-187 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
LPNANANF_01068 8.85e-304 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
LPNANANF_01069 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
LPNANANF_01070 4.38e-102 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
LPNANANF_01071 2.51e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
LPNANANF_01072 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LPNANANF_01073 9.49e-206 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
LPNANANF_01074 2.67e-52 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LPNANANF_01075 6.8e-309 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LPNANANF_01076 3.05e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LPNANANF_01077 2.2e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LPNANANF_01078 1.36e-87 yqhY - - S - - - protein conserved in bacteria
LPNANANF_01079 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
LPNANANF_01080 4.67e-86 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
LPNANANF_01081 2.74e-94 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
LPNANANF_01082 5.53e-147 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
LPNANANF_01083 1.05e-130 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
LPNANANF_01084 1.5e-260 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
LPNANANF_01085 3.72e-55 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
LPNANANF_01086 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
LPNANANF_01087 9.44e-110 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
LPNANANF_01088 3.64e-220 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
LPNANANF_01089 9.89e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
LPNANANF_01090 6.82e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LPNANANF_01091 7.36e-250 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
LPNANANF_01092 4.66e-117 yqhR - - S - - - Conserved membrane protein YqhR
LPNANANF_01093 7.33e-221 yqhQ - - S - - - Protein of unknown function (DUF1385)
LPNANANF_01094 7.65e-83 yqhP - - - - - - -
LPNANANF_01095 7e-210 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
LPNANANF_01096 5.64e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
LPNANANF_01097 1.58e-204 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
LPNANANF_01098 3.18e-84 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
LPNANANF_01099 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LPNANANF_01100 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LPNANANF_01101 3.32e-264 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
LPNANANF_01102 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
LPNANANF_01103 8.78e-195 yqhG - - S - - - Bacterial protein YqhG of unknown function
LPNANANF_01104 9.44e-32 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
LPNANANF_01105 2.75e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
LPNANANF_01106 3.67e-181 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
LPNANANF_01107 1.33e-102 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
LPNANANF_01108 1.9e-155 yqxM - - - ko:K19433 - ko00000 -
LPNANANF_01109 2.8e-70 yqzG - - S - - - Protein of unknown function (DUF3889)
LPNANANF_01110 2e-36 yqzE - - S - - - YqzE-like protein
LPNANANF_01111 3.31e-81 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
LPNANANF_01112 7.62e-99 comGF - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
LPNANANF_01113 2.94e-24 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
LPNANANF_01114 2.27e-93 - - - NU ko:K02246,ko:K08084 - ko00000,ko00002,ko02044 Tfp pilus assembly protein FimT
LPNANANF_01115 4.46e-66 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
LPNANANF_01116 8.04e-234 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
LPNANANF_01117 7.75e-258 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LPNANANF_01118 4.53e-239 yqxL - - P - - - Mg2 transporter protein
LPNANANF_01119 3.76e-304 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
LPNANANF_01120 1.44e-190 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LPNANANF_01122 1.15e-86 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
LPNANANF_01123 4.19e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
LPNANANF_01124 8.14e-156 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
LPNANANF_01125 1.07e-28 yqgW - - S - - - Protein of unknown function (DUF2759)
LPNANANF_01126 2.99e-65 dglA - - S - - - Thiamine-binding protein
LPNANANF_01127 2.11e-253 yqgU - - - - - - -
LPNANANF_01128 1.14e-280 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
LPNANANF_01129 1.18e-227 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
LPNANANF_01130 1.21e-274 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
LPNANANF_01131 5.38e-11 yqgO - - - - - - -
LPNANANF_01132 4.27e-126 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LPNANANF_01133 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
LPNANANF_01134 3.42e-68 yqzD - - - - - - -
LPNANANF_01135 2.5e-99 yqzC - - S - - - Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LPNANANF_01136 1.34e-187 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LPNANANF_01137 3.39e-185 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LPNANANF_01138 1.68e-198 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
LPNANANF_01139 1.75e-203 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
LPNANANF_01140 2.24e-206 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
LPNANANF_01141 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
LPNANANF_01142 2.37e-289 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
LPNANANF_01143 4.22e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
LPNANANF_01144 2.76e-99 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
LPNANANF_01145 2.18e-167 yqgB - - S - - - Protein of unknown function (DUF1189)
LPNANANF_01146 8.76e-63 yqfZ - - M ko:K06417 - ko00000 LysM domain
LPNANANF_01147 1.97e-256 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LPNANANF_01148 3.34e-80 yqfX - - S - - - membrane
LPNANANF_01149 4.78e-141 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
LPNANANF_01150 3.19e-100 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
LPNANANF_01151 5.44e-199 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
LPNANANF_01152 8.63e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
LPNANANF_01153 9.96e-213 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LPNANANF_01154 2.4e-314 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
LPNANANF_01155 4.16e-89 yqfQ - - S - - - YqfQ-like protein
LPNANANF_01156 3.53e-226 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LPNANANF_01157 1.79e-267 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LPNANANF_01158 6e-162 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
LPNANANF_01159 9.68e-83 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
LPNANANF_01160 3.97e-255 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
LPNANANF_01161 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
LPNANANF_01162 5.52e-112 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
LPNANANF_01163 5.46e-192 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
LPNANANF_01164 2.4e-144 ccpN - - K - - - CBS domain
LPNANANF_01165 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
LPNANANF_01166 5.19e-223 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
LPNANANF_01167 8.73e-186 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
LPNANANF_01168 6e-24 - - - S - - - YqzL-like protein
LPNANANF_01169 2.01e-214 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LPNANANF_01170 1.92e-92 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
LPNANANF_01171 5.28e-83 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
LPNANANF_01172 5.87e-104 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LPNANANF_01173 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
LPNANANF_01174 1.01e-223 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
LPNANANF_01175 3.88e-284 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
LPNANANF_01176 3.57e-61 yqfC - - S - - - sporulation protein YqfC
LPNANANF_01177 3.47e-83 yqfB - - - - - - -
LPNANANF_01178 2.37e-177 yqfA - - S - - - UPF0365 protein
LPNANANF_01179 3.14e-294 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
LPNANANF_01180 7.84e-91 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
LPNANANF_01181 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
LPNANANF_01182 5.59e-201 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
LPNANANF_01183 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
LPNANANF_01184 5.03e-181 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
LPNANANF_01185 8.96e-223 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
LPNANANF_01186 4.93e-266 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
LPNANANF_01187 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
LPNANANF_01188 4.25e-109 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LPNANANF_01189 5.74e-240 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
LPNANANF_01190 1.38e-274 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
LPNANANF_01191 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
LPNANANF_01192 2.1e-71 yqxA - - S - - - Protein of unknown function (DUF3679)
LPNANANF_01193 9.09e-280 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
LPNANANF_01194 2.51e-260 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
LPNANANF_01195 1.91e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
LPNANANF_01196 4.48e-233 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
LPNANANF_01197 9.65e-22 - - - S - - - YqzM-like protein
LPNANANF_01198 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
LPNANANF_01199 3.79e-136 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
LPNANANF_01200 1.63e-133 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
LPNANANF_01201 1.39e-191 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LPNANANF_01202 4.66e-176 yqeM - - Q - - - Methyltransferase
LPNANANF_01203 4.65e-80 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
LPNANANF_01204 2.38e-133 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
LPNANANF_01205 2.89e-140 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LPNANANF_01206 3.12e-61 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
LPNANANF_01207 2.95e-201 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LPNANANF_01208 7.6e-270 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
LPNANANF_01209 5.51e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
LPNANANF_01211 1.78e-178 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
LPNANANF_01212 8.09e-181 pdaC 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
LPNANANF_01213 4.84e-137 yqeD - - S - - - SNARE associated Golgi protein
LPNANANF_01214 3.36e-31 - 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
LPNANANF_01215 1.34e-278 - - - EGP - - - Transmembrane secretion effector
LPNANANF_01216 2.27e-160 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LPNANANF_01217 3.58e-202 - - - S - - - Carbohydrate esterase, sialic acid-specific acetylesterase
LPNANANF_01218 1.51e-117 - - - K - - - Transcriptional regulator PadR-like family
LPNANANF_01220 2.1e-190 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
LPNANANF_01221 5.27e-126 yqaC - - F - - - adenylate kinase activity
LPNANANF_01222 8.62e-47 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 COG0477 Permeases of the major facilitator superfamily
LPNANANF_01223 4.79e-140 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 COG0477 Permeases of the major facilitator superfamily
LPNANANF_01224 8.64e-105 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
LPNANANF_01225 1.6e-119 - - - S - - - DinB family
LPNANANF_01226 8.38e-190 supH - - S - - - hydrolase
LPNANANF_01227 6.84e-186 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
LPNANANF_01228 2.9e-168 - - - K - - - Helix-turn-helix domain, rpiR family
LPNANANF_01229 2.42e-238 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
LPNANANF_01230 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LPNANANF_01231 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
LPNANANF_01232 8.05e-232 romA - - S - - - Beta-lactamase superfamily domain
LPNANANF_01233 3.95e-108 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LPNANANF_01234 5.33e-211 yybE - - K - - - Transcriptional regulator
LPNANANF_01235 9.26e-271 yybF1 - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
LPNANANF_01236 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
LPNANANF_01237 4.77e-130 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
LPNANANF_01238 1.82e-120 yrhH - - Q - - - methyltransferase
LPNANANF_01239 2.37e-07 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
LPNANANF_01240 3.96e-183 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
LPNANANF_01241 1.54e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
LPNANANF_01242 0.0 yrhE 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
LPNANANF_01243 3.91e-105 yrhD - - S - - - Protein of unknown function (DUF1641)
LPNANANF_01244 9.51e-47 yrhC - - S - - - YrhC-like protein
LPNANANF_01245 1.31e-268 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
LPNANANF_01246 1.87e-217 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
LPNANANF_01247 8.02e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LPNANANF_01248 7.78e-150 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
LPNANANF_01249 5.12e-38 yrzA - - S - - - Protein of unknown function (DUF2536)
LPNANANF_01250 2.92e-123 yrrS - - S - - - Protein of unknown function (DUF1510)
LPNANANF_01251 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
LPNANANF_01252 1.62e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LPNANANF_01253 2.61e-147 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
LPNANANF_01254 1.09e-311 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
LPNANANF_01255 2.57e-221 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
LPNANANF_01256 2.32e-153 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
LPNANANF_01257 6.36e-256 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LPNANANF_01258 7.2e-61 yrzB - - S - - - Belongs to the UPF0473 family
LPNANANF_01259 2.72e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LPNANANF_01260 1.1e-55 yrzL - - S - - - Belongs to the UPF0297 family
LPNANANF_01261 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LPNANANF_01262 5.69e-238 yrrI - - S - - - AI-2E family transporter
LPNANANF_01263 2.69e-169 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
LPNANANF_01264 9e-189 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
LPNANANF_01265 7.95e-140 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LPNANANF_01266 1.54e-138 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LPNANANF_01267 6.52e-13 - - - S - - - Protein of unknown function (DUF3918)
LPNANANF_01268 8.4e-42 yrzR - - - - - - -
LPNANANF_01269 4.14e-106 yrrD - - S - - - protein conserved in bacteria
LPNANANF_01270 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
LPNANANF_01271 1.12e-23 yrrB - - S - - - COG0457 FOG TPR repeat
LPNANANF_01272 3.55e-282 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
LPNANANF_01273 2.56e-270 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
LPNANANF_01274 9.19e-84 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
LPNANANF_01275 7.55e-303 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
LPNANANF_01276 1.18e-178 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
LPNANANF_01277 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LPNANANF_01278 3e-310 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
LPNANANF_01281 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
LPNANANF_01282 4.95e-98 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
LPNANANF_01283 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LPNANANF_01284 5.1e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LPNANANF_01285 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
LPNANANF_01286 9.09e-62 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
LPNANANF_01287 3.1e-112 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
LPNANANF_01288 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LPNANANF_01289 3.33e-66 yrzD - - S - - - Post-transcriptional regulator
LPNANANF_01290 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LPNANANF_01291 2.03e-143 yrbG - - S - - - membrane
LPNANANF_01292 9.08e-81 yrzE - - S - - - Protein of unknown function (DUF3792)
LPNANANF_01293 2.09e-50 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
LPNANANF_01294 4.74e-292 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
LPNANANF_01295 2.36e-245 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LPNANANF_01296 9.76e-29 yrzS - - S - - - Protein of unknown function (DUF2905)
LPNANANF_01297 3.57e-236 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
LPNANANF_01298 2.33e-136 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
LPNANANF_01299 1.21e-120 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
LPNANANF_01301 3.13e-61 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LPNANANF_01302 5.42e-251 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
LPNANANF_01303 1.73e-271 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LPNANANF_01304 1.23e-194 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
LPNANANF_01305 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
LPNANANF_01306 6.4e-282 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
LPNANANF_01307 2.39e-121 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
LPNANANF_01308 8.16e-206 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
LPNANANF_01309 5.94e-95 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
LPNANANF_01310 7.1e-311 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LPNANANF_01311 2.87e-137 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
LPNANANF_01312 7.74e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
LPNANANF_01313 1.42e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
LPNANANF_01314 1.28e-65 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
LPNANANF_01315 4.19e-205 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
LPNANANF_01316 5.66e-188 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
LPNANANF_01317 3.94e-184 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
LPNANANF_01318 6.85e-155 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
LPNANANF_01319 6.14e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
LPNANANF_01320 4.34e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
LPNANANF_01321 1.06e-234 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
LPNANANF_01322 2.5e-164 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
LPNANANF_01323 2.76e-129 maf - - D ko:K06287 - ko00000 septum formation protein Maf
LPNANANF_01324 1.8e-208 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
LPNANANF_01325 1.27e-171 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
LPNANANF_01326 7.3e-305 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
LPNANANF_01327 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
LPNANANF_01328 4.38e-35 - - - - - - - -
LPNANANF_01329 1.81e-249 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LPNANANF_01330 1.61e-177 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
LPNANANF_01331 2.57e-309 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
LPNANANF_01332 3.43e-236 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
LPNANANF_01333 2.12e-179 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
LPNANANF_01334 8.6e-222 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
LPNANANF_01335 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
LPNANANF_01336 4.36e-315 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LPNANANF_01337 8.26e-116 ysxD - - - - - - -
LPNANANF_01338 1.79e-137 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
LPNANANF_01339 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LPNANANF_01340 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
LPNANANF_01341 1.34e-295 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LPNANANF_01342 2.54e-286 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
LPNANANF_01343 1.35e-240 ysoA - - H - - - Tetratricopeptide repeat
LPNANANF_01344 3.77e-150 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LPNANANF_01345 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LPNANANF_01346 1.23e-254 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
LPNANANF_01347 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LPNANANF_01348 2.75e-244 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LPNANANF_01349 2.06e-109 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
LPNANANF_01350 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
LPNANANF_01357 6.72e-118 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
LPNANANF_01358 1.59e-131 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LPNANANF_01359 1.44e-170 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LPNANANF_01360 1.82e-254 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
LPNANANF_01361 1.15e-196 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
LPNANANF_01362 3.77e-97 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
LPNANANF_01363 6.32e-42 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
LPNANANF_01364 8.94e-100 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
LPNANANF_01365 4.34e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
LPNANANF_01366 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
LPNANANF_01367 2.73e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
LPNANANF_01368 2.45e-103 yslB - - S - - - Protein of unknown function (DUF2507)
LPNANANF_01369 1.01e-273 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
LPNANANF_01370 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
LPNANANF_01371 1.6e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
LPNANANF_01372 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
LPNANANF_01373 4.11e-226 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
LPNANANF_01374 1.74e-177 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
LPNANANF_01375 7.09e-178 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
LPNANANF_01376 6.22e-134 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
LPNANANF_01377 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
LPNANANF_01378 5.46e-158 ywbB - - S - - - Protein of unknown function (DUF2711)
LPNANANF_01379 3.09e-88 yshE - - S ko:K08989 - ko00000 membrane
LPNANANF_01380 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
LPNANANF_01381 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
LPNANANF_01382 6.04e-109 yshB - - S - - - membrane protein, required for colicin V production
LPNANANF_01383 1.47e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LPNANANF_01384 3.08e-215 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LPNANANF_01385 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LPNANANF_01386 2.19e-249 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LPNANANF_01387 7.68e-172 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LPNANANF_01388 1.07e-43 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
LPNANANF_01389 3.06e-262 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
LPNANANF_01390 0.0 - 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD binding domain
LPNANANF_01391 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
LPNANANF_01392 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
LPNANANF_01393 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
LPNANANF_01394 1.18e-191 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
LPNANANF_01395 1.25e-214 araP - - P ko:K10189,ko:K10241,ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PFAM binding-protein-dependent transport systems inner membrane component
LPNANANF_01396 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
LPNANANF_01397 4.72e-285 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
LPNANANF_01398 1.7e-178 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
LPNANANF_01399 3.43e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
LPNANANF_01400 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
LPNANANF_01401 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
LPNANANF_01402 1.16e-239 abnA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
LPNANANF_01403 2.15e-262 ysdC - - G - - - COG1363 Cellulase M and related proteins
LPNANANF_01404 6.58e-88 ysdB - - S - - - Sigma-w pathway protein YsdB
LPNANANF_01405 1.34e-56 ysdA - - S - - - Membrane
LPNANANF_01406 2.3e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LPNANANF_01407 1.95e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
LPNANANF_01408 1.79e-112 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LPNANANF_01409 4.4e-147 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
LPNANANF_01410 1.12e-68 - - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 effector of murein hydrolase LrgA
LPNANANF_01411 6.06e-167 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
LPNANANF_01412 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LPNANANF_01413 2.94e-193 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
LPNANANF_01414 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LPNANANF_01415 4.68e-196 ytxC - - S - - - YtxC-like family
LPNANANF_01416 4.45e-140 ytxB - - S - - - SNARE associated Golgi protein
LPNANANF_01417 2.87e-219 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
LPNANANF_01418 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
LPNANANF_01419 5.95e-106 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LPNANANF_01420 1.82e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
LPNANANF_01421 2.19e-249 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LPNANANF_01422 9.78e-89 ytcD - - K - - - Transcriptional regulator
LPNANANF_01423 1.61e-258 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
LPNANANF_01424 4.54e-205 ytbE - - S - - - reductase
LPNANANF_01425 4.17e-128 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LPNANANF_01426 2e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
LPNANANF_01427 9.87e-203 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
LPNANANF_01428 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LPNANANF_01430 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
LPNANANF_01431 4.82e-166 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LPNANANF_01432 1.48e-217 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
LPNANANF_01433 5.36e-308 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
LPNANANF_01434 2.02e-268 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
LPNANANF_01435 5.5e-83 yjdF3 - - S - - - Protein of unknown function (DUF2992)
LPNANANF_01436 1.62e-95 ytwI - - S - - - membrane
LPNANANF_01437 2.01e-247 ytvI - - S - - - sporulation integral membrane protein YtvI
LPNANANF_01438 6.91e-84 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
LPNANANF_01439 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
LPNANANF_01440 3.98e-230 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
LPNANANF_01441 3.28e-232 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
LPNANANF_01442 8.46e-206 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LPNANANF_01443 4.23e-287 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
LPNANANF_01444 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
LPNANANF_01445 4.94e-75 ytrH - - S - - - Sporulation protein YtrH
LPNANANF_01446 2.64e-114 ytrI - - - - - - -
LPNANANF_01447 2.87e-31 - - - - - - - -
LPNANANF_01448 2.14e-231 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
LPNANANF_01449 3.57e-62 ytpI - - S - - - YtpI-like protein
LPNANANF_01450 1.94e-304 ytoI - - K - - - transcriptional regulator containing CBS domains
LPNANANF_01451 4.16e-166 ytkL - - S - - - Belongs to the UPF0173 family
LPNANANF_01452 2.06e-184 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LPNANANF_01454 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
LPNANANF_01455 1.23e-296 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
LPNANANF_01456 4.03e-115 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
LPNANANF_01457 2.71e-280 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LPNANANF_01458 2.92e-232 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
LPNANANF_01459 1.36e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LPNANANF_01460 4.77e-100 ytfJ - - S - - - Sporulation protein YtfJ
LPNANANF_01461 1.22e-154 ytfI - - S - - - Protein of unknown function (DUF2953)
LPNANANF_01462 1.6e-113 yteJ - - S - - - RDD family
LPNANANF_01463 1.83e-234 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
LPNANANF_01464 9.45e-196 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LPNANANF_01465 0.0 ytcJ - - S - - - amidohydrolase
LPNANANF_01466 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
LPNANANF_01467 2.05e-42 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
LPNANANF_01468 1.21e-286 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LPNANANF_01469 2.25e-265 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
LPNANANF_01470 3.39e-309 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
LPNANANF_01471 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LPNANANF_01472 4.88e-195 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
LPNANANF_01473 1.4e-140 yttP - - K - - - Transcriptional regulator
LPNANANF_01474 8.64e-112 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
LPNANANF_01475 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
LPNANANF_01476 5.75e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LPNANANF_01477 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
LPNANANF_01478 3.71e-09 - - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
LPNANANF_01481 7.37e-19 - - - - - - - -
LPNANANF_01482 1.95e-22 - - - L - - - Integrase
LPNANANF_01483 3.57e-281 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LPNANANF_01485 1.65e-118 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
LPNANANF_01487 5.87e-177 - - - E - - - GDSL-like Lipase/Acylhydrolase family
LPNANANF_01489 4.99e-193 - - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LPNANANF_01490 7.76e-191 - - - K - - - Transcriptional regulator
LPNANANF_01491 2.86e-160 ygaZ - - E - - - AzlC protein
LPNANANF_01492 8.79e-64 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
LPNANANF_01493 5.98e-304 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LPNANANF_01494 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
LPNANANF_01495 4.04e-155 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
LPNANANF_01496 3.42e-149 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
LPNANANF_01497 1.66e-291 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
LPNANANF_01498 4.27e-155 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
LPNANANF_01499 2.12e-185 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
LPNANANF_01500 5.91e-235 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
LPNANANF_01501 1.54e-249 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
LPNANANF_01502 1.19e-57 ytxJ - - O - - - Protein of unknown function (DUF2847)
LPNANANF_01503 1.83e-30 ytxH - - S - - - COG4980 Gas vesicle protein
LPNANANF_01504 5.38e-26 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LPNANANF_01505 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
LPNANANF_01506 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
LPNANANF_01507 8.47e-139 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LPNANANF_01508 1.69e-190 ytpQ - - S - - - Belongs to the UPF0354 family
LPNANANF_01509 1.57e-75 ytpP - - CO - - - Thioredoxin
LPNANANF_01510 5.77e-102 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
LPNANANF_01511 4.15e-258 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
LPNANANF_01512 9.96e-69 ytzB - - S - - - small secreted protein
LPNANANF_01513 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
LPNANANF_01514 1.08e-208 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
LPNANANF_01515 6.43e-160 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
LPNANANF_01516 3.88e-60 ytzH - - S - - - YtzH-like protein
LPNANANF_01517 2.93e-199 ytmP - - M - - - Phosphotransferase
LPNANANF_01518 6.85e-226 ytlR - - I - - - Diacylglycerol kinase catalytic domain
LPNANANF_01519 4.22e-216 ytlQ - - - - - - -
LPNANANF_01520 1.28e-131 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LPNANANF_01521 1.95e-221 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
LPNANANF_01522 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
LPNANANF_01523 1.22e-289 pbuO - - S ko:K06901 - ko00000,ko02000 permease
LPNANANF_01524 3.25e-272 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
LPNANANF_01525 2.69e-165 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
LPNANANF_01526 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
LPNANANF_01527 5.02e-168 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
LPNANANF_01528 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LPNANANF_01529 1.52e-298 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
LPNANANF_01530 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
LPNANANF_01531 2.14e-36 yteV - - S - - - Sporulation protein Cse60
LPNANANF_01532 2.24e-238 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
LPNANANF_01533 2.28e-310 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
LPNANANF_01534 1.31e-216 - - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LPNANANF_01535 2.88e-184 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
LPNANANF_01536 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
LPNANANF_01537 5.68e-110 - - - M - - - Acetyltransferase (GNAT) domain
LPNANANF_01538 8.6e-69 ytwF - - P - - - Sulfurtransferase
LPNANANF_01539 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
LPNANANF_01540 7.19e-69 ytvB - - S - - - Protein of unknown function (DUF4257)
LPNANANF_01541 7.93e-176 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
LPNANANF_01542 3.91e-268 yttB - - EGP - - - Major facilitator superfamily
LPNANANF_01543 3.12e-162 ywaF - - S - - - Integral membrane protein
LPNANANF_01544 0.0 bceB - - V ko:K02004,ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
LPNANANF_01545 4.63e-174 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
LPNANANF_01546 2.19e-215 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
LPNANANF_01547 9.07e-167 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LPNANANF_01548 4.54e-286 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
LPNANANF_01549 2.12e-161 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LPNANANF_01550 1.49e-208 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
LPNANANF_01551 2.14e-234 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
LPNANANF_01552 8.97e-227 ytrC - - S ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
LPNANANF_01553 4.38e-209 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LPNANANF_01554 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
LPNANANF_01555 7.09e-53 ytzC - - S - - - Protein of unknown function (DUF2524)
LPNANANF_01556 5.76e-245 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
LPNANANF_01557 3.1e-137 ytqB - - J - - - Putative rRNA methylase
LPNANANF_01559 6.51e-179 - 3.1.4.46, 5.4.2.11 - C ko:K01126,ko:K01834 ko00010,ko00260,ko00564,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00564,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 glycerophosphoryl diester phosphodiesterase
LPNANANF_01560 2.02e-271 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
LPNANANF_01561 6.95e-194 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
LPNANANF_01562 4.06e-84 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LPNANANF_01563 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
LPNANANF_01564 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
LPNANANF_01565 7.88e-287 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LPNANANF_01566 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LPNANANF_01567 2.85e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
LPNANANF_01568 1.29e-188 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
LPNANANF_01569 3.06e-237 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
LPNANANF_01570 5.87e-182 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
LPNANANF_01571 5.66e-169 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
LPNANANF_01572 1.01e-114 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
LPNANANF_01573 1.23e-79 ytkC - - S - - - Bacteriophage holin family
LPNANANF_01574 1.8e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
LPNANANF_01576 2.98e-99 ytkA - - S - - - YtkA-like
LPNANANF_01577 7.16e-114 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
LPNANANF_01578 1.99e-52 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
LPNANANF_01579 9.31e-137 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
LPNANANF_01580 1.23e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
LPNANANF_01581 4.48e-313 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
LPNANANF_01582 7.77e-237 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
LPNANANF_01583 1.92e-34 - - - S - - - Domain of Unknown Function (DUF1540)
LPNANANF_01584 4.98e-273 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
LPNANANF_01585 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
LPNANANF_01586 7.52e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LPNANANF_01587 2.52e-199 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
LPNANANF_01588 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LPNANANF_01589 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
LPNANANF_01590 3.03e-169 yteA - - T - - - COG1734 DnaK suppressor protein
LPNANANF_01591 2.04e-99 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
LPNANANF_01600 3.67e-71 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
LPNANANF_01601 6.14e-172 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
LPNANANF_01602 4.38e-121 yobS - - K - - - Transcriptional regulator
LPNANANF_01603 1.63e-173 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
LPNANANF_01604 3.86e-119 yobW - - - - - - -
LPNANANF_01605 6.33e-72 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
LPNANANF_01606 1.19e-157 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
LPNANANF_01607 8.99e-116 yozB - - S ko:K08976 - ko00000 membrane
LPNANANF_01608 3.38e-179 - - - J - - - Protein required for attachment to host cells
LPNANANF_01609 2.27e-123 yocC - - - - - - -
LPNANANF_01610 3.33e-241 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
LPNANANF_01612 5.65e-167 yocH - - M - - - COG1388 FOG LysM repeat
LPNANANF_01613 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
LPNANANF_01614 2.32e-144 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LPNANANF_01616 4.5e-79 yocK - - T - - - general stress protein
LPNANANF_01617 2.71e-13 yocL - - - - - - -
LPNANANF_01618 3.51e-13 yocN - - - - - - -
LPNANANF_01619 2.29e-116 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
LPNANANF_01620 9.63e-60 yozN - - - - - - -
LPNANANF_01621 6.36e-50 yocN - - - - - - -
LPNANANF_01622 5.32e-75 yozO - - S - - - Bacterial PH domain
LPNANANF_01624 4.69e-43 yozC - - - - - - -
LPNANANF_01625 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
LPNANANF_01626 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
LPNANANF_01627 8.22e-213 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
LPNANANF_01628 1.45e-298 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
LPNANANF_01629 1.9e-212 yocS - - S ko:K03453 - ko00000 -transporter
LPNANANF_01630 7.76e-181 - - - S - - - Metallo-beta-lactamase superfamily
LPNANANF_01631 7.41e-263 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
LPNANANF_01632 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
LPNANANF_01633 0.0 yojO - - P - - - Von Willebrand factor
LPNANANF_01634 4.2e-209 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
LPNANANF_01635 5.36e-144 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LPNANANF_01636 9.65e-290 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
LPNANANF_01637 3.48e-287 - - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
LPNANANF_01638 1.11e-142 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LPNANANF_01640 2.39e-310 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
LPNANANF_01641 7.14e-194 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LPNANANF_01642 1.57e-162 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
LPNANANF_01643 8.09e-80 yojF - - S - - - Protein of unknown function (DUF1806)
LPNANANF_01644 5.2e-31 - - - - - - - -
LPNANANF_01645 2.96e-210 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
LPNANANF_01646 1.63e-104 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
LPNANANF_01648 1.5e-88 iolK - - S - - - tautomerase
LPNANANF_01649 8.87e-89 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
LPNANANF_01650 2.42e-74 yodB - - K - - - transcriptional
LPNANANF_01651 1.35e-138 yodC - - C - - - nitroreductase
LPNANANF_01652 9.89e-140 yahD - - S ko:K06999 - ko00000 Carboxylesterase
LPNANANF_01653 2.56e-220 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
LPNANANF_01654 1.97e-28 - - - S - - - Protein of unknown function (DUF3311)
LPNANANF_01655 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LPNANANF_01656 0.0 - 3.2.1.45 GH30 M ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 ko00000,ko00001,ko01000 Glycosyl hydrolase family 30 beta sandwich domain
LPNANANF_01657 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LPNANANF_01658 2.9e-168 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
LPNANANF_01659 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
LPNANANF_01660 5.03e-165 yodH - - Q - - - Methyltransferase
LPNANANF_01661 6.87e-50 yodI - - - - - - -
LPNANANF_01662 7.76e-193 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
LPNANANF_01663 1.05e-161 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
LPNANANF_01665 1.16e-72 yodL - - S - - - YodL-like
LPNANANF_01666 2.92e-131 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
LPNANANF_01667 9.77e-34 yozD - - S - - - YozD-like protein
LPNANANF_01669 1.9e-161 yodN - - - - - - -
LPNANANF_01670 2.45e-48 yozE - - S - - - Belongs to the UPF0346 family
LPNANANF_01671 8.13e-62 yokU - - S - - - YokU-like protein, putative antitoxin
LPNANANF_01672 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
LPNANANF_01673 1.64e-202 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
LPNANANF_01674 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
LPNANANF_01675 4.64e-160 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
LPNANANF_01676 9.76e-161 atoD 2.8.3.8, 2.8.3.9 - I ko:K01034 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LPNANANF_01677 3.97e-311 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LPNANANF_01678 8.35e-84 - - - L - - - Bacterial transcription activator, effector binding domain
LPNANANF_01680 1.99e-185 yiiD - - K ko:K06323 - ko00000 acetyltransferase
LPNANANF_01681 0.0 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
LPNANANF_01682 4.54e-60 cgeC - - - ko:K06321 - ko00000 -
LPNANANF_01683 3.12e-90 cgeA - - - ko:K06319 - ko00000 -
LPNANANF_01684 3.84e-232 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
LPNANANF_01685 7.47e-281 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
LPNANANF_01686 5.03e-95 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
LPNANANF_01688 1.01e-24 - - - L - - - Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
LPNANANF_01692 1.52e-98 yoqH - - M - - - LysM domain
LPNANANF_01693 1.8e-250 - - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
LPNANANF_01695 7.53e-69 - - - S - - - amine dehydrogenase activity
LPNANANF_01697 3.93e-58 - - - S - - - Acetyltransferase (GNAT) domain
LPNANANF_01698 2.67e-101 yokK - - S - - - SMI1 / KNR4 family
LPNANANF_01699 2.76e-115 - - - S ko:K21490 - ko00000,ko02048 SMI1 / KNR4 family (SUKH-1)
LPNANANF_01700 0.0 - - - UW ko:K21487,ko:K21489,ko:K21491,ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
LPNANANF_01701 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LPNANANF_01702 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
LPNANANF_01703 4.54e-238 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
LPNANANF_01704 6.11e-311 yoeA - - V - - - MATE efflux family protein
LPNANANF_01705 1.75e-123 yoeB - - S - - - IseA DL-endopeptidase inhibitor
LPNANANF_01707 3.97e-125 - - - L - - - Integrase
LPNANANF_01708 6.69e-47 yoeD - - G - - - Helix-turn-helix domain
LPNANANF_01709 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
LPNANANF_01710 2.77e-255 - - - EGP ko:K08164 - ko00000,ko02000 -transporter
LPNANANF_01711 1.91e-66 - - - K - - - Helix-turn-helix domain
LPNANANF_01712 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LPNANANF_01713 3.7e-199 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
LPNANANF_01714 3.47e-55 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
LPNANANF_01715 4.73e-131 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
LPNANANF_01716 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
LPNANANF_01717 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
LPNANANF_01718 3.04e-204 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
LPNANANF_01719 2.07e-261 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LPNANANF_01720 8.39e-182 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LPNANANF_01721 8.13e-82 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
LPNANANF_01722 4.95e-160 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
LPNANANF_01723 1.56e-52 - - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LPNANANF_01724 8.29e-174 yoxB - - - - - - -
LPNANANF_01725 1.56e-261 yoaB - - EGP - - - the major facilitator superfamily
LPNANANF_01726 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
LPNANANF_01727 7.32e-247 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LPNANANF_01728 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LPNANANF_01731 3.84e-127 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
LPNANANF_01732 4.7e-57 - - - - - - - -
LPNANANF_01733 5.48e-112 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
LPNANANF_01734 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
LPNANANF_01735 3.77e-23 - - - G - - - SMI1-KNR4 cell-wall
LPNANANF_01736 9.7e-69 - - - G - - - SMI1-KNR4 cell-wall
LPNANANF_01737 2.4e-107 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
LPNANANF_01738 0.0 yokA - - L - - - Recombinase
LPNANANF_01739 9.83e-134 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
LPNANANF_01740 4.61e-106 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
LPNANANF_01741 1.99e-132 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LPNANANF_01742 3.35e-89 ypoP - - K - - - transcriptional
LPNANANF_01743 5.59e-126 ypmS - - S - - - protein conserved in bacteria
LPNANANF_01744 2.58e-176 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
LPNANANF_01745 1.3e-145 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
LPNANANF_01746 8.98e-55 ypmP - - S - - - Protein of unknown function (DUF2535)
LPNANANF_01747 4.25e-309 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LPNANANF_01748 8.24e-224 yplP - - K - - - Transcriptional regulator
LPNANANF_01749 1.5e-142 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
LPNANANF_01750 4.04e-149 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
LPNANANF_01751 3.01e-117 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LPNANANF_01752 2.53e-203 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LPNANANF_01753 1.31e-147 ypjP - - S - - - YpjP-like protein
LPNANANF_01754 1.22e-172 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
LPNANANF_01755 4.8e-99 yphP - - S - - - Belongs to the UPF0403 family
LPNANANF_01756 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
LPNANANF_01757 1.27e-200 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
LPNANANF_01758 3.97e-129 yagB - - S ko:K06950 - ko00000 phosphohydrolase
LPNANANF_01759 2.27e-112 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
LPNANANF_01760 2.3e-227 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LPNANANF_01761 6.07e-274 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
LPNANANF_01762 2.54e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
LPNANANF_01763 5.19e-17 degR - - - - - - -
LPNANANF_01764 1.13e-49 - - - S - - - Protein of unknown function (DUF2564)
LPNANANF_01765 6.59e-40 ypeQ - - S - - - Zinc-finger
LPNANANF_01766 5.91e-159 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
LPNANANF_01767 2.79e-154 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LPNANANF_01768 2.11e-89 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
LPNANANF_01770 4.73e-210 ypcP - - L - - - 5'3' exonuclease
LPNANANF_01771 2.44e-10 - - - - - - - -
LPNANANF_01772 1.17e-51 ypbS - - S - - - Protein of unknown function (DUF2533)
LPNANANF_01773 0.0 ypbR - - S - - - Dynamin family
LPNANANF_01774 1.26e-117 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
LPNANANF_01775 2.54e-268 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
LPNANANF_01776 8.42e-135 - - - J - - - Acetyltransferase (GNAT) domain
LPNANANF_01777 3.81e-67 MGMT - - L ko:K07443 - ko00000 6-O-methylguanine DNA methyltransferase, DNA binding domain
LPNANANF_01778 1.53e-12 - - - S - - - Bacillus cereus group antimicrobial protein
LPNANANF_01779 3.88e-127 ydfR - - S - - - Protein of unknown function (DUF421)
LPNANANF_01780 3.79e-131 yrdC - - Q - - - Isochorismatase family
LPNANANF_01781 1.78e-06 - - - S - - - Bacillus cereus group antimicrobial protein
LPNANANF_01782 3.42e-296 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine
LPNANANF_01783 2.34e-128 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
LPNANANF_01784 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
LPNANANF_01785 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
LPNANANF_01787 6.91e-31 - - - S - - - YpzG-like protein
LPNANANF_01788 4.39e-275 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
LPNANANF_01789 5.52e-61 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
LPNANANF_01790 1.33e-128 ypsA - - S - - - Belongs to the UPF0398 family
LPNANANF_01791 9.36e-48 cotD - - S ko:K06327 - ko00000 Inner spore coat protein D
LPNANANF_01793 8.7e-297 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
LPNANANF_01794 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
LPNANANF_01795 2.85e-114 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
LPNANANF_01796 5.29e-95 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
LPNANANF_01797 1.36e-76 yppG - - S - - - YppG-like protein
LPNANANF_01801 0.000542 - - - - ko:K06430 - ko00000 -
LPNANANF_01802 5.51e-237 yppC - - S - - - Protein of unknown function (DUF2515)
LPNANANF_01803 2.54e-145 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
LPNANANF_01804 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
LPNANANF_01805 1.04e-118 ypoC - - - - - - -
LPNANANF_01806 1.02e-157 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LPNANANF_01807 3.42e-167 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
LPNANANF_01808 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
LPNANANF_01809 1.46e-283 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
LPNANANF_01810 1.6e-103 ypmB - - S - - - protein conserved in bacteria
LPNANANF_01811 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
LPNANANF_01812 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
LPNANANF_01813 2.41e-84 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LPNANANF_01814 1.15e-201 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LPNANANF_01815 2.31e-192 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
LPNANANF_01816 6.35e-230 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
LPNANANF_01817 2.41e-279 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
LPNANANF_01818 1.04e-268 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
LPNANANF_01819 4.48e-170 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
LPNANANF_01820 6.19e-94 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
LPNANANF_01821 2.8e-188 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
LPNANANF_01822 2.47e-74 ypjD - - S - - - Nucleotide pyrophosphohydrolase
LPNANANF_01823 4.31e-199 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
LPNANANF_01824 5.53e-287 - 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
LPNANANF_01825 2.05e-182 ypjB - - S - - - sporulation protein
LPNANANF_01826 7.24e-134 ypjA - - S - - - membrane
LPNANANF_01827 4.02e-191 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
LPNANANF_01828 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
LPNANANF_01829 2.86e-127 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
LPNANANF_01830 3.91e-100 ypiF - - S - - - Protein of unknown function (DUF2487)
LPNANANF_01831 2.6e-129 ypiB - - S - - - Belongs to the UPF0302 family
LPNANANF_01832 3.05e-298 ypiA - - S - - - COG0457 FOG TPR repeat
LPNANANF_01833 9.91e-302 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
LPNANANF_01834 4.34e-261 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
LPNANANF_01835 1.76e-256 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LPNANANF_01836 2.8e-187 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
LPNANANF_01837 1.42e-289 trpB 4.2.1.20 - E ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
LPNANANF_01838 4.31e-149 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
LPNANANF_01839 2.46e-169 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
LPNANANF_01840 2.76e-210 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LPNANANF_01841 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LPNANANF_01842 2.93e-79 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
LPNANANF_01843 7.79e-261 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LPNANANF_01844 2.29e-274 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LPNANANF_01845 2.49e-181 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
LPNANANF_01846 8.53e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
LPNANANF_01847 2.29e-251 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
LPNANANF_01848 7.76e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
LPNANANF_01849 1.61e-176 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
LPNANANF_01850 6.23e-47 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
LPNANANF_01851 6.27e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
LPNANANF_01852 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LPNANANF_01853 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LPNANANF_01854 3.4e-173 yphF - - - - - - -
LPNANANF_01855 3.25e-23 yphE - - S - - - Protein of unknown function (DUF2768)
LPNANANF_01856 4.93e-244 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
LPNANANF_01857 0.0 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
LPNANANF_01858 6.19e-136 yphA - - - - - - -
LPNANANF_01859 1.87e-12 - - - S - - - YpzI-like protein
LPNANANF_01860 5.92e-238 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
LPNANANF_01861 5.73e-264 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
LPNANANF_01862 2.36e-145 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
LPNANANF_01863 7.86e-18 - - - S - - - Family of unknown function (DUF5359)
LPNANANF_01864 5e-79 ypfA - - M - - - Flagellar protein YcgR
LPNANANF_01865 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
LPNANANF_01866 1.92e-204 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
LPNANANF_01867 3.7e-155 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
LPNANANF_01868 8.78e-238 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
LPNANANF_01869 1.81e-311 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
LPNANANF_01870 1.36e-136 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
LPNANANF_01871 4.68e-189 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
LPNANANF_01872 1.92e-111 ypbF - - S - - - Protein of unknown function (DUF2663)
LPNANANF_01873 1.3e-127 ypbE - - M - - - Lysin motif
LPNANANF_01874 1.09e-128 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
LPNANANF_01875 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
LPNANANF_01876 2.03e-251 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
LPNANANF_01877 5.88e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
LPNANANF_01878 2.16e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LPNANANF_01879 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LPNANANF_01880 3.25e-253 rsiX - - - - - - -
LPNANANF_01881 3.22e-135 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LPNANANF_01882 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LPNANANF_01883 9.77e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LPNANANF_01884 4.39e-252 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
LPNANANF_01885 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
LPNANANF_01886 3.04e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
LPNANANF_01887 1.49e-167 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
LPNANANF_01888 8.99e-116 spmB - - S ko:K06374 - ko00000 Spore maturation protein
LPNANANF_01889 3.75e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
LPNANANF_01890 3.26e-275 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
LPNANANF_01891 6.14e-122 ypuI - - S - - - Protein of unknown function (DUF3907)
LPNANANF_01892 2.73e-133 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LPNANANF_01893 2.09e-166 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LPNANANF_01895 8.11e-121 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
LPNANANF_01896 2.74e-84 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LPNANANF_01897 6.92e-106 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
LPNANANF_01898 7.34e-291 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LPNANANF_01899 3.97e-144 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
LPNANANF_01900 1.31e-268 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LPNANANF_01901 4.92e-71 ypuD - - - - - - -
LPNANANF_01902 2.67e-130 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
LPNANANF_01903 1.42e-107 ccdC1 - - O - - - Protein of unknown function (DUF1453)
LPNANANF_01904 4.12e-104 ppiB 5.2.1.8 - O ko:K01802,ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LPNANANF_01905 6.31e-199 ypuA - - S - - - Secreted protein
LPNANANF_01906 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
LPNANANF_01907 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
LPNANANF_01908 1.85e-142 - - - S ko:K06407 - ko00000 stage V sporulation protein
LPNANANF_01909 1.51e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
LPNANANF_01910 7.86e-242 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
LPNANANF_01911 2.85e-103 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
LPNANANF_01912 1.43e-78 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
LPNANANF_01913 6.68e-143 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
LPNANANF_01914 1.37e-173 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LPNANANF_01915 4.77e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
LPNANANF_01916 4.86e-77 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
LPNANANF_01917 2.47e-273 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
LPNANANF_01918 9.06e-192 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LPNANANF_01919 4.97e-294 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
LPNANANF_01920 2.26e-213 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
LPNANANF_01921 9.51e-51 - - - S - - - Protein of unknown function (DUF4227)
LPNANANF_01922 4.56e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
LPNANANF_01923 3.53e-142 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
LPNANANF_01925 1.26e-46 yqkK - - - - - - -
LPNANANF_01926 1.96e-30 - - - - - - - -
LPNANANF_01927 4.12e-310 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
LPNANANF_01928 8.36e-312 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
LPNANANF_01929 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
LPNANANF_01930 1.3e-240 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
LPNANANF_01931 4e-76 ansR - - K - - - Transcriptional regulator
LPNANANF_01932 2.93e-280 yqxK - - L - - - DNA helicase
LPNANANF_01933 1.04e-122 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
LPNANANF_01934 2.01e-10 - - - S - - - Protein of unknown function (DUF3936)
LPNANANF_01935 5.35e-217 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
LPNANANF_01936 1.94e-09 yqkE - - S - - - Protein of unknown function (DUF3886)
LPNANANF_01937 1.6e-223 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
LPNANANF_01938 7.88e-54 yqkC - - S - - - Protein of unknown function (DUF2552)
LPNANANF_01939 5.4e-80 yqkB - - S - - - Belongs to the HesB IscA family
LPNANANF_01940 4.31e-225 yqkA - - K - - - GrpB protein
LPNANANF_01941 2.43e-80 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
LPNANANF_01942 4.67e-114 yqjY - - K ko:K06977 - ko00000 acetyltransferase
LPNANANF_01943 2.7e-298 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LPNANANF_01944 9.19e-76 - - - S - - - YolD-like protein
LPNANANF_01946 2.91e-238 yueF - - S - - - transporter activity
LPNANANF_01948 4.44e-95 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LPNANANF_01949 6.33e-227 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
LPNANANF_01950 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
LPNANANF_01951 5.87e-181 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
LPNANANF_01952 2.9e-225 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
LPNANANF_01953 6.79e-186 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LPNANANF_01954 1.14e-173 - - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
LPNANANF_01955 1.85e-304 - 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
LPNANANF_01956 8.08e-281 - 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
LPNANANF_01957 0.0 - 1.6.5.5 - C ko:K00344 - ko00000,ko01000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
LPNANANF_01958 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
LPNANANF_01959 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
LPNANANF_01960 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
LPNANANF_01961 1.29e-280 glcP1 - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
LPNANANF_01962 5.18e-313 gabT 2.6.1.19 - E ko:K00823 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LPNANANF_01963 5.68e-233 suhB 3.1.3.25, 3.1.3.7 - G ko:K01082,ko:K01092 ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070 ko00000,ko00001,ko00002,ko01000,ko03016 inositol monophosphate 1-phosphatase activity
LPNANANF_01964 7.7e-254 - 1.1.1.14, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00008 ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
LPNANANF_01965 1.11e-287 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
LPNANANF_01966 4.41e-222 ybaS - - S - - - Na -dependent transporter
LPNANANF_01967 5.05e-139 ybbA - - S ko:K07017 - ko00000 Putative esterase
LPNANANF_01968 2.04e-229 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LPNANANF_01969 1.8e-225 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LPNANANF_01970 7.85e-216 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
LPNANANF_01971 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
LPNANANF_01972 5.26e-299 ybbC - - S - - - protein conserved in bacteria
LPNANANF_01973 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
LPNANANF_01974 1.32e-310 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
LPNANANF_01975 3.7e-313 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LPNANANF_01976 1.1e-206 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LPNANANF_01977 1.75e-110 ybbJ - - J - - - acetyltransferase
LPNANANF_01978 3.89e-101 ybbK - - S - - - Protein of unknown function (DUF523)
LPNANANF_01984 4.59e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LPNANANF_01985 3.19e-151 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
LPNANANF_01986 9e-188 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LPNANANF_01987 6.17e-292 ybbR - - S - - - protein conserved in bacteria
LPNANANF_01988 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LPNANANF_01989 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
LPNANANF_01990 2.14e-199 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
LPNANANF_01991 1.85e-134 - - - S - - - ABC-2 family transporter protein
LPNANANF_01992 6.3e-23 ybdN - - - - - - -
LPNANANF_01993 4.2e-07 - - - Q ko:K16123,ko:K16124 ko01054,map01054 ko00000,ko00001,ko01008 Non-ribosomal peptide synthetase modules and related proteins
LPNANANF_01994 8.72e-163 - - - T ko:K11630 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LPNANANF_01995 6.93e-237 - - - T ko:K19168 - ko00000,ko02048 Histidine kinase
LPNANANF_01996 6.57e-176 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LPNANANF_01997 0.0 - - - V ko:K02004,ko:K11632 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
LPNANANF_01998 6.94e-16 - - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LPNANANF_01999 1.03e-206 dkgB - - S - - - Aldo/keto reductase family
LPNANANF_02000 7.37e-136 yxaC - - M - - - effector of murein hydrolase
LPNANANF_02001 1.41e-67 - - - S ko:K06518 - ko00000,ko02000 LrgA family
LPNANANF_02002 5.62e-93 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
LPNANANF_02004 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
LPNANANF_02005 5.32e-119 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
LPNANANF_02006 5.23e-257 - - - T - - - COG4585 Signal transduction histidine kinase
LPNANANF_02007 1.68e-140 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
LPNANANF_02008 7.57e-215 yfiL - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
LPNANANF_02009 1.58e-263 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
LPNANANF_02010 9.29e-253 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
LPNANANF_02011 2.34e-35 - - - - - - - -
LPNANANF_02012 1.81e-103 - - - S - - - Domain of unknown function (DUF4879)
LPNANANF_02013 2.48e-52 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
LPNANANF_02014 8.39e-143 yqeB - - - - - - -
LPNANANF_02015 7.84e-55 ybyB - - - - - - -
LPNANANF_02016 0.0 ybeC - - E - - - amino acid
LPNANANF_02018 1.27e-22 - - - S - - - Protein of unknown function (DUF2651)
LPNANANF_02019 4.93e-212 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
LPNANANF_02020 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
LPNANANF_02021 5.8e-23 - - - S - - - Protein of unknown function (DUF2651)
LPNANANF_02022 3.89e-265 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
LPNANANF_02024 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
LPNANANF_02025 2.99e-46 - - - - - - - -
LPNANANF_02026 4.85e-107 - - - K - - - Helix-turn-helix XRE-family like proteins
LPNANANF_02027 5.77e-246 ypjH - - C ko:K08317 - ko00000,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
LPNANANF_02028 5.37e-270 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LPNANANF_02029 3.15e-120 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LPNANANF_02030 4.26e-113 ybfM - - S - - - SNARE associated Golgi protein
LPNANANF_02031 7.49e-195 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
LPNANANF_02032 2.58e-56 ybfN - - - - - - -
LPNANANF_02033 5.76e-245 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
LPNANANF_02034 1.17e-271 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LPNANANF_02035 5.02e-256 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
LPNANANF_02036 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
LPNANANF_02037 3.97e-228 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
LPNANANF_02038 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
LPNANANF_02039 1.11e-240 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
LPNANANF_02040 2.65e-280 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LPNANANF_02041 5.81e-221 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
LPNANANF_02042 8.06e-159 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
LPNANANF_02043 5.89e-36 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
LPNANANF_02044 2.12e-198 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LPNANANF_02045 1.64e-143 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
LPNANANF_02046 1.19e-232 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
LPNANANF_02047 1.14e-83 ydfP - - S ko:K15977 - ko00000 DoxX
LPNANANF_02048 2.19e-73 ydfQ - - CO - - - Thioredoxin
LPNANANF_02049 1.63e-82 ycbP - - S - - - Protein of unknown function (DUF2512)
LPNANANF_02050 2.13e-101 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
LPNANANF_02051 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
LPNANANF_02052 8.68e-36 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
LPNANANF_02053 1.42e-159 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LPNANANF_02054 8.1e-153 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
LPNANANF_02055 1.16e-264 ycbU - - E - - - Selenocysteine lyase
LPNANANF_02056 2.5e-313 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
LPNANANF_02057 2.56e-129 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
LPNANANF_02058 1.48e-249 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
LPNANANF_02059 3.29e-147 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
LPNANANF_02060 1.13e-250 yccF - - K ko:K07039 - ko00000 SEC-C motif
LPNANANF_02061 1.08e-218 yccK - - C - - - Aldo keto reductase
LPNANANF_02062 2.28e-226 ycdA - - S - - - Domain of unknown function (DUF5105)
LPNANANF_02063 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LPNANANF_02064 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LPNANANF_02065 7.3e-121 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
LPNANANF_02066 2.86e-248 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
LPNANANF_02067 1.43e-177 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
LPNANANF_02068 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
LPNANANF_02069 1.04e-213 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
LPNANANF_02070 5.69e-170 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
LPNANANF_02071 1.19e-174 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
LPNANANF_02072 9.86e-237 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LPNANANF_02073 4.06e-140 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
LPNANANF_02074 7.32e-136 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
LPNANANF_02075 2.46e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
LPNANANF_02076 6.08e-178 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
LPNANANF_02077 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
LPNANANF_02078 1.17e-246 yceH - - P - - - Belongs to the TelA family
LPNANANF_02079 1.05e-275 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
LPNANANF_02080 7.71e-294 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
LPNANANF_02081 2.45e-185 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
LPNANANF_02082 7e-211 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
LPNANANF_02083 3.77e-269 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
LPNANANF_02084 8.03e-294 ycgA - - S - - - Membrane
LPNANANF_02085 8.91e-106 ycgB - - - - - - -
LPNANANF_02086 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
LPNANANF_02087 6.6e-228 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
LPNANANF_02088 0.0 mdr - - EGP - - - the major facilitator superfamily
LPNANANF_02089 6.92e-101 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
LPNANANF_02090 2.61e-146 ycgF - - E - - - Lysine exporter protein LysE YggA
LPNANANF_02091 2.33e-189 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
LPNANANF_02092 6.64e-314 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
LPNANANF_02093 3.76e-145 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
LPNANANF_02094 2.13e-190 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
LPNANANF_02095 7.2e-09 - - - S - - - Bacillus cereus group antimicrobial protein
LPNANANF_02096 1.66e-173 - 4.2.1.118 - G ko:K15652 ko00400,ko01110,ko01130,map00400,map01110,map01130 ko00000,ko00001,ko01000 Xylose isomerase-like TIM barrel
LPNANANF_02097 5.79e-289 - - - G ko:K08191,ko:K08194 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
LPNANANF_02098 8.64e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LPNANANF_02099 1.15e-233 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
LPNANANF_02100 2.67e-184 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
LPNANANF_02101 9.61e-217 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
LPNANANF_02102 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
LPNANANF_02103 6.34e-311 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LPNANANF_02104 1.43e-290 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
LPNANANF_02105 3.33e-242 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
LPNANANF_02106 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
LPNANANF_02107 5.95e-75 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
LPNANANF_02108 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LPNANANF_02109 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LPNANANF_02110 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
LPNANANF_02111 2.34e-284 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
LPNANANF_02112 1.66e-288 yciC - - S - - - GTPases (G3E family)
LPNANANF_02113 3.04e-282 fdh 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
LPNANANF_02114 1.09e-95 yckC - - S - - - membrane
LPNANANF_02115 9.5e-68 - - - S - - - Protein of unknown function (DUF2680)
LPNANANF_02116 5.81e-92 nin - - S - - - Competence protein J (ComJ)
LPNANANF_02117 7.65e-101 nucA - - M - - - Deoxyribonuclease NucA/NucB
LPNANANF_02118 3.11e-124 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
LPNANANF_02119 5.21e-138 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
LPNANANF_02120 4.1e-84 hxlR - - K - - - transcriptional
LPNANANF_02125 2.41e-234 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LPNANANF_02126 5.22e-112 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
LPNANANF_02127 4.14e-162 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
LPNANANF_02128 1.41e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
LPNANANF_02129 7.58e-244 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LPNANANF_02130 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
LPNANANF_02131 2.95e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
LPNANANF_02132 1.29e-149 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LPNANANF_02133 1.72e-29 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
LPNANANF_02134 1.92e-161 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LPNANANF_02135 1.11e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
LPNANANF_02136 1.67e-164 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
LPNANANF_02137 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LPNANANF_02138 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
LPNANANF_02139 8.97e-192 ydjC - - S - - - Abhydrolase domain containing 18
LPNANANF_02140 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
LPNANANF_02141 1.02e-256 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
LPNANANF_02142 9.08e-317 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
LPNANANF_02143 4.24e-221 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
LPNANANF_02144 5.13e-41 yjdJ - - S - - - Domain of unknown function (DUF4306)
LPNANANF_02145 2.35e-147 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
LPNANANF_02146 1.04e-227 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LPNANANF_02147 7.49e-161 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
LPNANANF_02148 4.01e-217 ydjI - - S - - - virion core protein (lumpy skin disease virus)
LPNANANF_02149 0.0 oatA - - I - - - Acyltransferase family
LPNANANF_02150 9.73e-194 rsiV - - S - - - Protein of unknown function (DUF3298)
LPNANANF_02151 1.87e-113 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LPNANANF_02152 1e-248 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
LPNANANF_02153 4.58e-82 ydjM - - M - - - Lytic transglycolase
LPNANANF_02154 4.57e-193 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
LPNANANF_02156 2.02e-47 ydjO - - S - - - Cold-inducible protein YdjO
LPNANANF_02157 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
LPNANANF_02158 8.75e-315 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
LPNANANF_02159 1.96e-195 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LPNANANF_02160 2.79e-226 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
LPNANANF_02161 7.37e-273 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
LPNANANF_02162 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
LPNANANF_02163 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
LPNANANF_02164 1.65e-165 - - - K - - - Acetyltransferase (GNAT) domain
LPNANANF_02165 6.37e-120 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LPNANANF_02166 8.71e-313 - - - S - - - Domain of unknown function (DUF4179)
LPNANANF_02167 2.49e-269 pbuG - - S ko:K06901 - ko00000,ko02000 permease
LPNANANF_02168 2.94e-166 yebC - - M - - - Membrane
LPNANANF_02170 2.66e-120 yebE - - S - - - UPF0316 protein
LPNANANF_02171 2.21e-38 yebG - - S - - - NETI protein
LPNANANF_02172 1.13e-108 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LPNANANF_02173 9.19e-287 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LPNANANF_02174 6.38e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LPNANANF_02175 3.53e-168 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
LPNANANF_02176 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LPNANANF_02177 1.1e-165 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LPNANANF_02178 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LPNANANF_02179 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LPNANANF_02180 4.38e-243 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
LPNANANF_02181 8.53e-136 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LPNANANF_02182 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
LPNANANF_02183 5.69e-298 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
LPNANANF_02184 2.07e-34 - - - S - - - Protein of unknown function (DUF2892)
LPNANANF_02185 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
LPNANANF_02186 9.98e-246 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
LPNANANF_02187 8.28e-67 yerC - - S - - - protein conserved in bacteria
LPNANANF_02188 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
LPNANANF_02189 8.71e-164 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
LPNANANF_02190 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
LPNANANF_02191 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LPNANANF_02192 5.54e-286 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
LPNANANF_02193 2.98e-247 yerI - - S - - - homoserine kinase type II (protein kinase fold)
LPNANANF_02194 1.44e-158 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
LPNANANF_02195 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LPNANANF_02196 1.81e-60 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LPNANANF_02197 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
LPNANANF_02198 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LPNANANF_02199 3.85e-198 yerO - - K - - - Transcriptional regulator
LPNANANF_02200 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LPNANANF_02201 5.16e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
LPNANANF_02202 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LPNANANF_02203 2.08e-102 vraR - - KT ko:K07694,ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LPNANANF_02205 4.42e-45 - - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
LPNANANF_02206 4.7e-82 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LPNANANF_02207 7.21e-246 - 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LPNANANF_02208 2.48e-169 - 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 3-oxoacyl-[acyl-carrier-protein] synthase activity
LPNANANF_02209 1.82e-144 - 1.1.1.100 - IQ ko:K00059,ko:K07535 ko00061,ko00333,ko00362,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,ko01220,map00061,map00333,map00362,map00780,map01040,map01100,map01120,map01130,map01212,map01220 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
LPNANANF_02210 1.12e-201 cylA - - V ko:K01990,ko:K09695,ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
LPNANANF_02211 6.78e-176 cylB - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
LPNANANF_02212 5.06e-47 - - - S - - - Protein of unknown function, DUF600
LPNANANF_02213 9.83e-82 - - - S - - - Protein of unknown function, DUF600
LPNANANF_02214 2.49e-68 - - - S - - - Protein of unknown function, DUF600
LPNANANF_02215 2.98e-59 - - - S - - - Protein of unknown function, DUF600
LPNANANF_02216 4.91e-71 - - - S - - - Protein of unknown function, DUF600
LPNANANF_02217 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 nucleic acid phosphodiester bond hydrolysis
LPNANANF_02218 3.12e-162 yeeN - - K - - - transcriptional regulatory protein
LPNANANF_02220 7.39e-138 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
LPNANANF_02221 2.67e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
LPNANANF_02222 1.62e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
LPNANANF_02223 1.48e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
LPNANANF_02224 3.42e-124 yesJ - - K - - - Acetyltransferase (GNAT) family
LPNANANF_02225 4.2e-05 - - - - - - - -
LPNANANF_02226 5.2e-156 yetF - - S - - - membrane
LPNANANF_02227 1.11e-72 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
LPNANANF_02228 3.78e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LPNANANF_02229 7.64e-198 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LPNANANF_02230 1.34e-31 - - - S - - - Uncharacterized small protein (DUF2292)
LPNANANF_02231 1.82e-73 - - - H - - - riboflavin kinase activity
LPNANANF_02232 3.63e-135 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
LPNANANF_02233 6.96e-116 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
LPNANANF_02234 1.36e-261 yetM - - CH - - - FAD binding domain
LPNANANF_02235 1.38e-251 yetN - - S - - - Protein of unknown function (DUF3900)
LPNANANF_02236 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
LPNANANF_02238 5.83e-67 - - - K - - - Winged helix DNA-binding domain
LPNANANF_02239 2.64e-212 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
LPNANANF_02240 5.34e-162 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
LPNANANF_02242 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
LPNANANF_02243 2.94e-188 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
LPNANANF_02244 9.26e-218 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
LPNANANF_02245 2.81e-231 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
LPNANANF_02246 1.78e-285 yfnE - - S - - - Glycosyltransferase like family 2
LPNANANF_02247 1.51e-235 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
LPNANANF_02248 2.7e-278 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
LPNANANF_02249 8.03e-311 yfnA - - E ko:K03294 - ko00000 amino acid
LPNANANF_02250 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LPNANANF_02251 2.85e-169 yfmS - - NT - - - chemotaxis protein
LPNANANF_02252 8.54e-215 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
LPNANANF_02253 1.2e-265 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
LPNANANF_02254 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
LPNANANF_02255 5.04e-90 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
LPNANANF_02256 2.94e-263 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
LPNANANF_02257 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
LPNANANF_02258 1.25e-264 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
LPNANANF_02259 5.3e-24 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
LPNANANF_02260 2.51e-45 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
LPNANANF_02261 9.5e-239 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
LPNANANF_02262 7.35e-32 - - - S - - - Protein of unknown function (DUF3212)
LPNANANF_02263 4.9e-76 yflT - - S - - - Heat induced stress protein YflT
LPNANANF_02264 9.25e-308 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
LPNANANF_02265 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
LPNANANF_02268 3.01e-58 - - - Q - - - calcium- and calmodulin-responsive adenylate cyclase activity
LPNANANF_02269 1.04e-91 M1-820 - - Q - - - Collagen triple helix repeat (20 copies)
LPNANANF_02270 0.0 ywpD - - T - - - Histidine kinase
LPNANANF_02271 3.54e-193 M1-574 - - T - - - Transcriptional regulatory protein, C terminal
LPNANANF_02272 0.0 - - - M - - - cell wall anchor domain
LPNANANF_02273 1.06e-101 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
LPNANANF_02274 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
LPNANANF_02275 1.38e-154 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
LPNANANF_02276 7.99e-226 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
LPNANANF_02277 2.01e-287 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
LPNANANF_02278 4.87e-192 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
LPNANANF_02279 1.74e-278 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
LPNANANF_02280 2.76e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
LPNANANF_02281 5.07e-158 yflK - - S - - - protein conserved in bacteria
LPNANANF_02282 5.84e-21 yflJ - - S - - - Protein of unknown function (DUF2639)
LPNANANF_02283 1.98e-26 yflI - - - - - - -
LPNANANF_02284 1.67e-66 yflH - - S - - - Protein of unknown function (DUF3243)
LPNANANF_02285 3.67e-175 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
LPNANANF_02286 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
LPNANANF_02287 2.17e-94 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
LPNANANF_02288 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
LPNANANF_02289 8.46e-84 ydhN1 - - S - - - Domain of unknown function (DUF1992)
LPNANANF_02290 8.64e-106 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
LPNANANF_02291 8.17e-52 ydgA - - S - - - Spore germination protein gerPA/gerPF
LPNANANF_02292 1.85e-53 ydgB - - S - - - Spore germination protein gerPA/gerPF
LPNANANF_02293 2.13e-311 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LPNANANF_02294 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
LPNANANF_02295 1.18e-165 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
LPNANANF_02296 2.41e-157 frp - - C - - - nitroreductase
LPNANANF_02297 7e-166 yibF - - S - - - YibE/F-like protein
LPNANANF_02298 1.81e-254 yibE - - S - - - YibE/F-like protein
LPNANANF_02299 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
LPNANANF_02300 7.82e-118 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
LPNANANF_02301 2.24e-239 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
LPNANANF_02302 1.68e-207 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LPNANANF_02303 2.77e-172 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
LPNANANF_02304 1.64e-250 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
LPNANANF_02305 1.47e-41 yfkK - - S - - - Belongs to the UPF0435 family
LPNANANF_02306 1.69e-112 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LPNANANF_02307 1.45e-67 yfkI - - S - - - gas vesicle protein
LPNANANF_02308 1.12e-184 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
LPNANANF_02309 6.71e-12 - - - - - - - -
LPNANANF_02310 5.89e-278 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
LPNANANF_02311 1.4e-237 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
LPNANANF_02312 8.04e-186 yfkD - - S - - - YfkD-like protein
LPNANANF_02313 5.2e-189 yfkC - - M - - - Mechanosensitive ion channel
LPNANANF_02314 1.69e-281 yfkA - - S - - - YfkB-like domain
LPNANANF_02315 7.99e-37 yfjT - - - - - - -
LPNANANF_02316 2.53e-198 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
LPNANANF_02317 1.66e-186 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
LPNANANF_02319 2.61e-235 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
LPNANANF_02320 4.34e-202 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LPNANANF_02321 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LPNANANF_02323 5.95e-65 - - - S - - - YfzA-like protein
LPNANANF_02324 3.47e-244 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LPNANANF_02325 5.26e-113 yfjM - - S - - - Psort location Cytoplasmic, score
LPNANANF_02326 5.55e-244 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
LPNANANF_02327 3.74e-242 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LPNANANF_02328 5.38e-272 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LPNANANF_02329 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
LPNANANF_02330 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
LPNANANF_02331 6.64e-22 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
LPNANANF_02332 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
LPNANANF_02333 7.72e-179 glvR - - F ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
LPNANANF_02334 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LPNANANF_02335 0.0 yobO - - M - - - COG5434 Endopolygalacturonase
LPNANANF_02336 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
LPNANANF_02337 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
LPNANANF_02338 5.54e-82 yfiD3 - - S - - - DoxX
LPNANANF_02339 6.7e-205 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
LPNANANF_02340 3.45e-213 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
LPNANANF_02341 5.62e-126 padR - - K - - - transcriptional
LPNANANF_02342 3.61e-144 - 1.6.5.2 - S ko:K00355 ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
LPNANANF_02343 6.31e-235 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
LPNANANF_02344 0.0 - 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
LPNANANF_02345 2.87e-61 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
LPNANANF_02346 1.14e-128 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
LPNANANF_02347 0.0 yfiU - - EGP - - - the major facilitator superfamily
LPNANANF_02348 7.97e-108 yfiV - - K - - - transcriptional
LPNANANF_02349 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LPNANANF_02350 2.08e-208 yfhB - - S - - - PhzF family
LPNANANF_02351 8.22e-138 yfhC - - C - - - nitroreductase
LPNANANF_02352 8.55e-33 yfhD - - S - - - YfhD-like protein
LPNANANF_02354 8.54e-215 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
LPNANANF_02355 9e-183 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
LPNANANF_02356 4.58e-69 yfhH - - S - - - Protein of unknown function (DUF1811)
LPNANANF_02357 2.86e-268 yfhI - - EGP - - - -transporter
LPNANANF_02359 4.75e-214 mpr - - M - - - Belongs to the peptidase S1B family
LPNANANF_02360 2.57e-59 yfhJ - - S - - - WVELL protein
LPNANANF_02361 8.09e-122 yfhK - - T - - - Bacterial SH3 domain homologues
LPNANANF_02362 1.22e-56 yfhL - - S - - - SdpI/YhfL protein family
LPNANANF_02363 3.11e-215 - - - S - - - Alpha/beta hydrolase family
LPNANANF_02364 1.35e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
LPNANANF_02365 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
LPNANANF_02366 2.94e-236 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
LPNANANF_02367 1.07e-264 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
LPNANANF_02368 2.54e-50 yfhS - - - - - - -
LPNANANF_02369 5.41e-173 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LPNANANF_02370 4.77e-06 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
LPNANANF_02371 1.4e-49 ygaB - - S - - - YgaB-like protein
LPNANANF_02372 2.32e-135 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
LPNANANF_02373 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
LPNANANF_02374 9.11e-240 ygaE - - S - - - Membrane
LPNANANF_02375 6.86e-314 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
LPNANANF_02376 4.66e-110 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
LPNANANF_02377 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
LPNANANF_02378 2.71e-74 ygzB - - S - - - UPF0295 protein
LPNANANF_02379 1.12e-212 ygxA - - S - - - Nucleotidyltransferase-like
LPNANANF_02380 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LPNANANF_02381 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LPNANANF_02382 6.18e-52 yaaB - - S - - - Domain of unknown function (DUF370)
LPNANANF_02383 3.2e-264 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LPNANANF_02384 3.19e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
LPNANANF_02385 8.47e-264 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
LPNANANF_02386 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LPNANANF_02387 1.99e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
LPNANANF_02388 2.12e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LPNANANF_02389 3.14e-140 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
LPNANANF_02390 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LPNANANF_02391 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
LPNANANF_02392 2.29e-164 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
LPNANANF_02393 1.1e-193 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
LPNANANF_02394 1.23e-172 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
LPNANANF_02395 1.17e-188 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
LPNANANF_02396 8.14e-143 yyaC - - S - - - Sporulation protein YyaC
LPNANANF_02397 2.24e-106 yhhY - - K - - - FR47-like protein
LPNANANF_02398 1.67e-225 yyaD - - S - - - Membrane
LPNANANF_02399 1.5e-44 yyzM - - S - - - protein conserved in bacteria
LPNANANF_02400 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LPNANANF_02401 5.42e-254 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
LPNANANF_02402 2.9e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
LPNANANF_02403 1.37e-98 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
LPNANANF_02404 4.35e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LPNANANF_02405 1.04e-135 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
LPNANANF_02406 3.52e-130 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LPNANANF_02407 4.01e-185 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
LPNANANF_02408 4.85e-232 ccpB - - K - - - Transcriptional regulator
LPNANANF_02409 1.35e-85 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LPNANANF_02410 0.0 - - - G ko:K08369 - ko00000,ko02000 Sugar (and other) transporter
LPNANANF_02411 3.45e-209 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
LPNANANF_02412 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
LPNANANF_02413 1.82e-208 - - - S - - - Patatin-like phospholipase
LPNANANF_02414 5.46e-168 - - - EG - - - EamA-like transporter family
LPNANANF_02415 8.28e-310 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LPNANANF_02416 9.17e-35 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
LPNANANF_02417 3.13e-122 - - - - - - - -
LPNANANF_02418 3.89e-175 bdh 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
LPNANANF_02419 5.13e-213 - - - K - - - Transcriptional regulator
LPNANANF_02420 4.76e-87 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
LPNANANF_02421 1.66e-211 - - - M - - - Domain of Unknown Function (DUF1259)
LPNANANF_02422 1.28e-98 yjcF - - S - - - Acetyltransferase (GNAT) domain
LPNANANF_02423 1.3e-99 yybA - - K - - - transcriptional
LPNANANF_02424 2.99e-191 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
LPNANANF_02425 3.36e-90 - - - K - - - Winged helix DNA-binding domain
LPNANANF_02426 1.7e-148 ydgI - - C - - - nitroreductase
LPNANANF_02427 1.31e-72 ypaA - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
LPNANANF_02429 6.69e-204 - - - G - - - Major Facilitator Superfamily
LPNANANF_02430 9.17e-116 - - - S - - - PFAM DinB family protein
LPNANANF_02431 4.64e-150 - - - K - - - FCD domain
LPNANANF_02432 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
LPNANANF_02433 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
LPNANANF_02434 5.87e-197 ypaH - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
LPNANANF_02435 2.95e-211 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
LPNANANF_02436 4.56e-87 yybR - - K - - - Transcriptional regulator
LPNANANF_02437 9.54e-111 cotF - - M ko:K06329 - ko00000 Spore coat protein
LPNANANF_02439 5.01e-204 yybS - - S - - - membrane
LPNANANF_02440 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
LPNANANF_02441 1.58e-95 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
LPNANANF_02442 8.75e-160 - - - KLT - - - COG0515 Serine threonine protein kinase
LPNANANF_02443 2.62e-158 - - - S - - - GlcNAc-PI de-N-acetylase
LPNANANF_02444 1.95e-307 - - - M - - - Glycosyltransferase Family 4
LPNANANF_02445 6.85e-299 - - - S - - - Carbamoyl-phosphate synthase L chain, ATP binding domain
LPNANANF_02446 1.5e-257 - - - S - - - Ecdysteroid kinase
LPNANANF_02447 1.18e-310 - - - M - - - Glycosyltransferase Family 4
LPNANANF_02448 3.6e-25 yycC - - K - - - YycC-like protein
LPNANANF_02450 7.68e-39 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
LPNANANF_02451 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
LPNANANF_02452 1.91e-95 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LPNANANF_02453 1.06e-315 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LPNANANF_02458 1.51e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LPNANANF_02459 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LPNANANF_02460 0.0 yycH - - S - - - protein conserved in bacteria
LPNANANF_02461 2.81e-194 yycI - - S - - - protein conserved in bacteria
LPNANANF_02462 5.69e-191 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
LPNANANF_02463 1.63e-278 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LPNANANF_02464 2.5e-14 phoP1 - - KT ko:K02483 - ko00000,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LPNANANF_02465 0.0 - 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
LPNANANF_02466 1.45e-244 thiF 2.7.7.73 - H ko:K03148 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 ThiF family
LPNANANF_02467 0.0 - - - - - - - -
LPNANANF_02468 8.61e-257 - - - S - - - Major Facilitator Superfamily
LPNANANF_02469 0.0 - - - S - - - ABC transporter
LPNANANF_02470 4.53e-189 - 1.14.11.27 - P ko:K10277 - ko00000,ko01000,ko03036 peptidyl-arginine hydroxylation
LPNANANF_02471 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
LPNANANF_02472 2.69e-57 sdpR - - K - - - transcriptional
LPNANANF_02473 5.11e-85 yvaZ - - S - - - Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
LPNANANF_02474 6.81e-295 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
LPNANANF_02475 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
LPNANANF_02476 1.86e-212 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
LPNANANF_02477 1.35e-261 - - - S ko:K06361,ko:K06365,ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
LPNANANF_02479 2.92e-113 yycN - - K - - - Acetyltransferase
LPNANANF_02480 3.55e-232 - - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
LPNANANF_02481 5.6e-170 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
LPNANANF_02482 1.74e-272 yycP - - - - - - -
LPNANANF_02485 1.43e-105 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LPNANANF_02486 9.51e-18 - - - L ko:K07454 - ko00000 HNH endonuclease
LPNANANF_02487 1.22e-186 - 2.1.1.37 - H ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 PFAM C-5 cytosine-specific DNA methylase
LPNANANF_02488 1.68e-193 - 2.1.1.37 - H ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 PFAM C-5 cytosine-specific DNA methylase
LPNANANF_02490 9.44e-236 - - - S - - - Fusaric acid resistance protein-like
LPNANANF_02491 2.07e-237 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
LPNANANF_02492 4.17e-116 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
LPNANANF_02493 0.0 - - - C - - - COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
LPNANANF_02494 3.69e-195 - - - C - - - COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
LPNANANF_02495 2e-109 pucE 1.2.5.3 - C ko:K03518 - ko00000,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
LPNANANF_02496 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
LPNANANF_02497 5.26e-314 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
LPNANANF_02498 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
LPNANANF_02499 1.61e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
LPNANANF_02500 4.67e-163 - - - E - - - Ring-cleavage extradiol dioxygenase
LPNANANF_02501 7.8e-97 yxaI - - S - - - membrane protein domain
LPNANANF_02502 6.3e-255 - - - EGP - - - Major Facilitator Superfamily
LPNANANF_02503 1.21e-67 arsR3 - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
LPNANANF_02504 2.5e-85 - - - S - - - Family of unknown function (DUF5391)
LPNANANF_02505 4.61e-189 yxaL - - S - - - PQQ-like domain
LPNANANF_02506 0.0 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
LPNANANF_02507 6.59e-276 yxbF - - K - - - Bacterial regulatory proteins, tetR family
LPNANANF_02508 1.23e-255 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
LPNANANF_02509 1.6e-252 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LPNANANF_02510 2.62e-132 desR - - T ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LPNANANF_02511 3.56e-194 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
LPNANANF_02513 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
LPNANANF_02514 6.38e-313 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LPNANANF_02515 1.43e-223 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
LPNANANF_02516 6.09e-175 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
LPNANANF_02517 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LPNANANF_02518 6.96e-200 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
LPNANANF_02519 1.14e-230 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
LPNANANF_02520 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
LPNANANF_02521 2.2e-221 iolE 4.2.1.44 - H ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
LPNANANF_02522 1.74e-292 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
LPNANANF_02523 1.05e-249 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
LPNANANF_02524 1.08e-212 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
LPNANANF_02525 3.58e-202 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
LPNANANF_02526 1.91e-202 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
LPNANANF_02527 6.65e-157 - - - V - - - TIGRFAM NHLM bacteriocin system ABC transporter, peptidase ATP-binding protein
LPNANANF_02528 1.17e-210 - - - V - - - Domain of unknown function (DUF4135)
LPNANANF_02529 1.33e-46 - - - H - - - Flavoprotein
LPNANANF_02530 1.31e-09 - - - T - - - Transcriptional regulatory protein, C terminal
LPNANANF_02532 8.98e-169 - - - S ko:K20461 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
LPNANANF_02533 9.61e-168 - - - S ko:K20460 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 permease
LPNANANF_02534 7.54e-211 - - - V ko:K20459,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LPNANANF_02535 1.51e-174 yvrH - - T - - - Transcriptional regulator
LPNANANF_02536 0.0 - - - T - - - Histidine kinase
LPNANANF_02537 9.37e-159 yxdJ - - T ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LPNANANF_02538 6.53e-223 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LPNANANF_02539 3.28e-182 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LPNANANF_02540 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
LPNANANF_02541 4.03e-75 yxeA - - S - - - Protein of unknown function (DUF1093)
LPNANANF_02542 1.38e-226 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
LPNANANF_02543 1.61e-45 - - - - - - - -
LPNANANF_02544 1.68e-33 yxeD - - - - - - -
LPNANANF_02545 9.71e-41 yxeE - - - - - - -
LPNANANF_02548 1.34e-192 yxeH - - S - - - hydrolases of the HAD superfamily
LPNANANF_02549 5.8e-220 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
LPNANANF_02550 4.09e-145 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LPNANANF_02551 4.04e-265 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LPNANANF_02552 1.1e-296 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
LPNANANF_02553 0.0 hutM - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
LPNANANF_02554 3.25e-223 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
LPNANANF_02555 2.5e-296 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
LPNANANF_02556 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LPNANANF_02557 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
LPNANANF_02558 2.45e-103 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
LPNANANF_02559 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
LPNANANF_02560 8.46e-36 - - - - - - - -
LPNANANF_02561 2.75e-76 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LPNANANF_02562 6.99e-94 yxiE - - T - - - Belongs to the universal stress protein A family
LPNANANF_02563 1.46e-208 yxxF - - EG - - - EamA-like transporter family
LPNANANF_02564 9.42e-258 pelB 4.2.2.10, 4.2.2.2 - G ko:K01728,ko:K01732 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
LPNANANF_02565 0.0 wapA - - M - - - COG3209 Rhs family protein
LPNANANF_02566 2.27e-41 - - - - - - - -
LPNANANF_02570 7.46e-98 - - - - - - - -
LPNANANF_02572 1.67e-27 - - - - - - - -
LPNANANF_02574 1.53e-105 yxiI - - S - - - Protein of unknown function (DUF2716)
LPNANANF_02575 1.37e-78 - - - S - - - SMI1-KNR4 cell-wall
LPNANANF_02578 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
LPNANANF_02579 3.51e-280 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
LPNANANF_02580 1.64e-184 bglS - - M - - - licheninase activity
LPNANANF_02581 6.39e-281 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
LPNANANF_02582 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
LPNANANF_02583 2.68e-67 yxiS - - - - - - -
LPNANANF_02584 9.96e-108 - - - T - - - Domain of unknown function (DUF4163)
LPNANANF_02585 5.49e-266 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LPNANANF_02586 1.52e-205 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
LPNANANF_02587 2.8e-278 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
LPNANANF_02588 1.75e-110 yxjI - - S - - - LURP-one-related
LPNANANF_02591 2.82e-301 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
LPNANANF_02592 3.78e-249 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
LPNANANF_02593 1.55e-119 yxkC - - S - - - Domain of unknown function (DUF4352)
LPNANANF_02594 4.82e-190 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
LPNANANF_02595 1.85e-208 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
LPNANANF_02596 1.51e-260 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LPNANANF_02597 6.65e-198 yxkH - - G - - - Polysaccharide deacetylase
LPNANANF_02598 5.53e-288 cimH - - C - - - COG3493 Na citrate symporter
LPNANANF_02599 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
LPNANANF_02600 1.12e-241 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
LPNANANF_02601 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
LPNANANF_02602 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
LPNANANF_02603 7.23e-200 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LPNANANF_02604 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
LPNANANF_02605 2.26e-245 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
LPNANANF_02606 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
LPNANANF_02607 2.26e-268 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
LPNANANF_02608 4.52e-238 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
LPNANANF_02609 2.09e-212 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
LPNANANF_02610 0.0 ydhP 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LPNANANF_02611 3.88e-300 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LPNANANF_02612 5.34e-64 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LPNANANF_02613 1.18e-66 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LPNANANF_02614 2.1e-289 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LPNANANF_02615 1.51e-75 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
LPNANANF_02616 9.23e-214 cbrA3 - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
LPNANANF_02617 4.83e-231 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LPNANANF_02618 5.72e-221 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LPNANANF_02619 5.36e-144 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
LPNANANF_02621 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
LPNANANF_02622 4.46e-66 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
LPNANANF_02623 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LPNANANF_02624 1.18e-67 licA 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LPNANANF_02625 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
LPNANANF_02626 1.11e-260 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
LPNANANF_02627 8.87e-289 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LPNANANF_02628 1.96e-49 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LPNANANF_02629 1.04e-292 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
LPNANANF_02630 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LPNANANF_02631 5.83e-17 - - - S - - - D-Ala-teichoic acid biosynthesis protein
LPNANANF_02632 4.37e-214 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
LPNANANF_02633 1.85e-151 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
LPNANANF_02634 7.07e-249 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LPNANANF_02635 1.76e-64 ywaE - - K - - - Transcriptional regulator
LPNANANF_02636 3.64e-208 gspA - - M - - - General stress
LPNANANF_02637 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
LPNANANF_02638 3.28e-315 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LPNANANF_02639 1.51e-87 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
LPNANANF_02640 8.47e-284 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
LPNANANF_02641 3.92e-216 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
LPNANANF_02642 1.69e-182 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
LPNANANF_02643 2.61e-37 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
LPNANANF_02644 3.74e-143 ywbG - - M - - - effector of murein hydrolase
LPNANANF_02645 9.02e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
LPNANANF_02646 4.83e-202 ywbI - - K - - - Transcriptional regulator
LPNANANF_02647 2.62e-175 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
LPNANANF_02648 6.77e-145 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
LPNANANF_02649 8.53e-307 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
LPNANANF_02650 8.86e-145 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
LPNANANF_02651 6.68e-170 - - - S - - - Streptomycin biosynthesis protein StrF
LPNANANF_02652 5.92e-165 - - - H - - - Methionine biosynthesis protein MetW
LPNANANF_02654 6.43e-146 - - - K - - - Bacterial regulatory proteins, tetR family
LPNANANF_02655 2e-80 gtcA - - S - - - GtrA-like protein
LPNANANF_02656 7.3e-289 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LPNANANF_02657 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
LPNANANF_02658 5.74e-48 ydaS - - S - - - membrane
LPNANANF_02659 3.14e-228 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
LPNANANF_02660 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LPNANANF_02661 4.91e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
LPNANANF_02662 1.6e-82 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
LPNANANF_02663 1.03e-50 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
LPNANANF_02664 5.07e-98 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
LPNANANF_02665 7.63e-271 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
LPNANANF_02666 9.4e-178 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
LPNANANF_02667 2.71e-235 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LPNANANF_02668 5.31e-275 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
LPNANANF_02669 3.83e-270 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
LPNANANF_02671 4.68e-196 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
LPNANANF_02672 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LPNANANF_02673 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
LPNANANF_02674 3.52e-26 ywdA - - - - - - -
LPNANANF_02675 4.13e-187 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
LPNANANF_02676 1.32e-74 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
LPNANANF_02677 1.16e-114 ywdD - - - - - - -
LPNANANF_02679 1.9e-191 ywdF - - S - - - Glycosyltransferase like family 2
LPNANANF_02680 6.93e-169 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LPNANANF_02681 1.83e-61 ywdI - - S - - - Family of unknown function (DUF5327)
LPNANANF_02682 1.13e-292 ywdJ - - F - - - Xanthine uracil
LPNANANF_02683 2.17e-76 ywdK - - S - - - small membrane protein
LPNANANF_02684 6.51e-88 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
LPNANANF_02685 1.06e-182 spsA - - M - - - Spore Coat
LPNANANF_02686 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
LPNANANF_02687 7.21e-282 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
LPNANANF_02688 3.88e-205 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
LPNANANF_02689 1.23e-274 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
LPNANANF_02690 4.29e-173 spsF - - M ko:K07257 - ko00000 Spore Coat
LPNANANF_02691 3.42e-234 spsG - - M - - - Spore Coat
LPNANANF_02692 3.99e-177 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LPNANANF_02693 6.14e-232 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
LPNANANF_02694 1.36e-207 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
LPNANANF_02695 1.15e-112 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
LPNANANF_02696 7.63e-221 bcrA5 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LPNANANF_02697 4.23e-153 - - - S - - - ABC-2 family transporter protein
LPNANANF_02698 2.09e-49 - - - S - - - Putative adhesin
LPNANANF_02699 6.09e-161 - - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LPNANANF_02700 1.6e-200 - - - T - - - Histidine kinase
LPNANANF_02701 1.82e-313 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
LPNANANF_02702 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
LPNANANF_02703 0.0 rocB - - E - - - arginine degradation protein
LPNANANF_02704 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
LPNANANF_02705 2.43e-265 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
LPNANANF_02706 4.34e-281 ywfA - - EGP - - - -transporter
LPNANANF_02707 1.1e-143 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
LPNANANF_02708 9.82e-176 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
LPNANANF_02709 1.33e-179 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LPNANANF_02710 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
LPNANANF_02711 8.14e-265 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
LPNANANF_02712 9e-297 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
LPNANANF_02713 6.63e-178 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
LPNANANF_02714 4.87e-187 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
LPNANANF_02715 2.03e-225 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
LPNANANF_02716 2.4e-213 - - - S - - - Conserved hypothetical protein 698
LPNANANF_02717 4.54e-210 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
LPNANANF_02718 6.17e-202 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
LPNANANF_02720 3.34e-228 - - - - - - - -
LPNANANF_02723 3.6e-216 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC transporter (permease)
LPNANANF_02724 2.34e-211 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LPNANANF_02725 3.78e-120 - - - S - - - membrane
LPNANANF_02726 1.08e-67 - - - K ko:K10947 - ko00000,ko03000 PadR family transcriptional regulator
LPNANANF_02727 2.03e-144 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
LPNANANF_02728 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
LPNANANF_02729 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
LPNANANF_02730 2.02e-115 ywgA - - - ko:K09388 - ko00000 -
LPNANANF_02731 9.94e-316 potE5 - - E ko:K03294 - ko00000 C-terminus of AA_permease
LPNANANF_02732 4.16e-93 ywhA - - K - - - Transcriptional regulator
LPNANANF_02733 2.37e-34 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
LPNANANF_02734 3.84e-153 ywhC - - S - - - Peptidase family M50
LPNANANF_02735 1.92e-123 ywhD - - S - - - YwhD family
LPNANANF_02736 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
LPNANANF_02737 1.58e-203 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LPNANANF_02738 2.1e-215 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
LPNANANF_02741 3.44e-100 - - - CP - - - Membrane
LPNANANF_02743 1.18e-38 - - - S - - - Domain of unknown function (DUF4177)
LPNANANF_02744 2.41e-45 - - - - - - - -
LPNANANF_02745 7.54e-40 ydcG - - K ko:K07729 - ko00000,ko03000 sequence-specific DNA binding
LPNANANF_02747 1.16e-99 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
LPNANANF_02748 6.35e-296 ywhK - - CO - - - amine dehydrogenase activity
LPNANANF_02749 1.67e-306 ywhL - - CO - - - amine dehydrogenase activity
LPNANANF_02751 1.95e-56 ywiB - - S - - - protein conserved in bacteria
LPNANANF_02752 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
LPNANANF_02753 5.81e-271 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
LPNANANF_02754 1.33e-167 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
LPNANANF_02755 5.91e-176 ywiC - - S - - - YwiC-like protein
LPNANANF_02756 4.13e-109 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
LPNANANF_02757 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LPNANANF_02758 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
LPNANANF_02759 6.55e-126 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
LPNANANF_02760 1.45e-159 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
LPNANANF_02761 3.02e-136 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
LPNANANF_02762 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LPNANANF_02763 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
LPNANANF_02764 1.13e-58 ywjC - - - - - - -
LPNANANF_02765 7.44e-231 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
LPNANANF_02766 5.99e-286 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
LPNANANF_02767 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
LPNANANF_02768 7.99e-74 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
LPNANANF_02769 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
LPNANANF_02770 6.67e-120 ywjG - - S - - - Domain of unknown function (DUF2529)
LPNANANF_02771 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
LPNANANF_02772 5.51e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
LPNANANF_02773 2.22e-144 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LPNANANF_02774 5.55e-304 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LPNANANF_02775 1.43e-224 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
LPNANANF_02776 5.13e-304 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LPNANANF_02777 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
LPNANANF_02778 5.56e-136 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
LPNANANF_02779 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
LPNANANF_02780 3.73e-198 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
LPNANANF_02781 8.54e-123 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
LPNANANF_02782 6.14e-87 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LPNANANF_02783 1.11e-244 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LPNANANF_02784 9.87e-203 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
LPNANANF_02786 1.21e-78 ywlA - - S - - - Uncharacterised protein family (UPF0715)
LPNANANF_02787 3.26e-153 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
LPNANANF_02788 4.23e-99 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
LPNANANF_02789 1.78e-242 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
LPNANANF_02790 3.91e-118 mntP - - P - - - Probably functions as a manganese efflux pump
LPNANANF_02791 4.9e-100 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LPNANANF_02792 6.74e-106 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
LPNANANF_02793 3.68e-125 ywlG - - S - - - Belongs to the UPF0340 family
LPNANANF_02794 1.99e-299 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LPNANANF_02795 2.24e-147 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LPNANANF_02796 2.6e-79 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
LPNANANF_02797 3e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
LPNANANF_02798 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LPNANANF_02799 1.66e-82 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LPNANANF_02800 1.95e-116 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LPNANANF_02801 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LPNANANF_02802 1.1e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LPNANANF_02803 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LPNANANF_02804 8.24e-83 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
LPNANANF_02805 7.17e-118 ywmA - - - - - - -
LPNANANF_02806 2.25e-45 ywzB - - S - - - membrane
LPNANANF_02807 8.35e-175 ywmB - - S - - - TATA-box binding
LPNANANF_02808 7.05e-306 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LPNANANF_02809 4.93e-243 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
LPNANANF_02810 2.59e-160 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
LPNANANF_02811 1.23e-157 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
LPNANANF_02813 1.29e-186 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LPNANANF_02814 8.87e-245 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LPNANANF_02815 1.36e-117 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
LPNANANF_02816 1.49e-107 ywmF - - S - - - Peptidase M50
LPNANANF_02817 2.01e-16 csbD - - K - - - CsbD-like
LPNANANF_02818 2.86e-68 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
LPNANANF_02819 8.83e-81 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
LPNANANF_02820 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
LPNANANF_02821 1.08e-88 ywnA - - K - - - Transcriptional regulator
LPNANANF_02823 3.58e-155 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
LPNANANF_02824 3.41e-80 ywnC - - S - - - Family of unknown function (DUF5362)
LPNANANF_02825 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LPNANANF_02826 2.55e-90 ywnF - - S - - - Family of unknown function (DUF5392)
LPNANANF_02828 2.27e-114 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
LPNANANF_02829 2.17e-187 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
LPNANANF_02830 1.34e-94 ywnJ - - S - - - VanZ like family
LPNANANF_02831 5.79e-132 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
LPNANANF_02832 6e-267 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
LPNANANF_02833 1.29e-76 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
LPNANANF_02834 1.32e-291 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
LPNANANF_02835 2.28e-132 yjgF - - Q - - - Isochorismatase family
LPNANANF_02836 1.55e-309 ywoD - - EGP - - - Major facilitator superfamily
LPNANANF_02837 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
LPNANANF_02838 3.36e-271 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
LPNANANF_02839 3.58e-93 ywoH - - K - - - transcriptional
LPNANANF_02840 5.93e-60 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
LPNANANF_02841 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
LPNANANF_02842 1.03e-173 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
LPNANANF_02843 2.03e-182 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
LPNANANF_02844 2.7e-257 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
LPNANANF_02845 3.15e-98 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
LPNANANF_02846 1.87e-74 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
LPNANANF_02847 3.73e-90 ywpF - - S - - - YwpF-like protein
LPNANANF_02848 4.49e-82 ywpG - - - - - - -
LPNANANF_02849 5.13e-77 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
LPNANANF_02850 3.39e-181 glcR - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
LPNANANF_02851 1.51e-201 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
LPNANANF_02852 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
LPNANANF_02853 0.0 ywqB - - S - - - SWIM zinc finger
LPNANANF_02854 1.74e-21 - - - - - - - -
LPNANANF_02855 3.53e-152 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
LPNANANF_02856 2.21e-157 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
LPNANANF_02857 1.5e-181 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
LPNANANF_02858 1.68e-311 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LPNANANF_02859 8.42e-192 ywqG - - S - - - Domain of unknown function (DUF1963)
LPNANANF_02862 2.09e-50 ywqI - - S - - - Family of unknown function (DUF5344)
LPNANANF_02863 0.0 ywqJ - - S - - - Pre-toxin TG
LPNANANF_02864 4.49e-107 - - - S - - - Protein of unknown function (DUF2004)
LPNANANF_02865 3.63e-95 - - - S ko:K21494 - ko00000,ko02048 SMI1 / KNR4 family
LPNANANF_02866 4.05e-89 - - - - - - - -
LPNANANF_02867 2.06e-171 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
LPNANANF_02868 4e-201 - - - K - - - Transcriptional regulator
LPNANANF_02869 5.2e-121 ywqN - - S - - - NAD(P)H-dependent
LPNANANF_02871 8.62e-114 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
LPNANANF_02872 1.2e-131 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
LPNANANF_02873 3.53e-110 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
LPNANANF_02874 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
LPNANANF_02876 1.15e-143 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LPNANANF_02877 9.23e-270 cotH - - M ko:K06330 - ko00000 Spore Coat
LPNANANF_02878 1.29e-185 cotB - - - ko:K06325 - ko00000 -
LPNANANF_02879 1.4e-162 ywrJ - - - - - - -
LPNANANF_02880 4.25e-306 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LPNANANF_02881 5.35e-215 alsR - - K - - - LysR substrate binding domain
LPNANANF_02882 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
LPNANANF_02883 5.71e-191 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
LPNANANF_02884 1.75e-123 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
LPNANANF_02885 5.87e-116 batE - - T - - - Sh3 type 3 domain protein
LPNANANF_02886 1.34e-205 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
LPNANANF_02887 5.37e-205 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
LPNANANF_02888 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
LPNANANF_02889 4.8e-86 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
LPNANANF_02890 2.94e-203 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LPNANANF_02891 4.99e-227 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
LPNANANF_02892 5.06e-260 gerKC - - S - - - Spore germination B3/ GerAC like, C-terminal
LPNANANF_02893 3.61e-246 - - - E - - - Spore germination protein
LPNANANF_02894 8.89e-242 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
LPNANANF_02895 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
LPNANANF_02896 2.95e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
LPNANANF_02897 1.39e-280 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
LPNANANF_02898 4.04e-29 ywtC - - - - - - -
LPNANANF_02899 2.15e-301 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
LPNANANF_02900 9.04e-77 yttA - - S - - - Pfam Transposase IS66
LPNANANF_02901 1.3e-202 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
LPNANANF_02902 1.14e-229 ywtF_2 - - K - - - Transcriptional regulator
LPNANANF_02903 4.54e-316 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LPNANANF_02904 0.0 - - - J ko:K07011 - ko00000 Glycosyl transferase family 2
LPNANANF_02905 5.18e-273 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
LPNANANF_02906 1.09e-254 gerBB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
LPNANANF_02907 0.0 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
LPNANANF_02908 5.29e-238 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
LPNANANF_02909 4.35e-311 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LPNANANF_02910 1.76e-277 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LPNANANF_02911 1.06e-182 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
LPNANANF_02912 2.69e-91 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
LPNANANF_02913 0.0 - - - M - - - Glycosyltransferase like family 2
LPNANANF_02914 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LPNANANF_02915 1.45e-194 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
LPNANANF_02916 0.0 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
LPNANANF_02917 2.64e-211 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
LPNANANF_02918 1.21e-268 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
LPNANANF_02919 1.82e-203 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
LPNANANF_02920 3.22e-65 - - - - - - - -
LPNANANF_02921 0.0 lytB - - D - - - Stage II sporulation protein
LPNANANF_02922 0.0 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
LPNANANF_02923 4.22e-151 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
LPNANANF_02924 0.0 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LPNANANF_02925 6.63e-278 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
LPNANANF_02926 0.0 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LPNANANF_02927 0.0 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
LPNANANF_02928 9.6e-146 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
LPNANANF_02929 6.64e-184 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
LPNANANF_02930 1.44e-297 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
LPNANANF_02931 3.12e-233 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
LPNANANF_02932 3.48e-237 yvhJ - - K - - - Transcriptional regulator
LPNANANF_02933 2.94e-155 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
LPNANANF_02934 3.44e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
LPNANANF_02935 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LPNANANF_02936 1.78e-203 degV - - S - - - protein conserved in bacteria
LPNANANF_02937 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LPNANANF_02938 3.56e-57 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
LPNANANF_02939 3.53e-100 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
LPNANANF_02940 1.1e-97 yvyF - - S - - - flagellar protein
LPNANANF_02941 6.14e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
LPNANANF_02942 7.36e-104 yvyG - - NOU - - - FlgN protein
LPNANANF_02943 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
LPNANANF_02944 1.2e-208 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
LPNANANF_02945 2.8e-108 yviE - - - - - - -
LPNANANF_02946 1.23e-96 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
LPNANANF_02947 2.67e-43 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LPNANANF_02948 9.78e-173 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LPNANANF_02949 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LPNANANF_02950 1.66e-87 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
LPNANANF_02951 3.91e-11 fliT - - N ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
LPNANANF_02952 1.92e-89 - - - - - - - -
LPNANANF_02953 6.54e-132 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LPNANANF_02954 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
LPNANANF_02955 6.64e-233 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LPNANANF_02956 6.85e-192 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
LPNANANF_02957 5.11e-59 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
LPNANANF_02958 8.68e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
LPNANANF_02959 7.34e-197 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
LPNANANF_02960 4.92e-304 ywoF - - P - - - Right handed beta helix region
LPNANANF_02961 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
LPNANANF_02962 2.47e-73 swrA - - S - - - Swarming motility protein
LPNANANF_02963 6.18e-282 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LPNANANF_02965 5.86e-25 - - - E - - - Saccharopine dehydrogenase
LPNANANF_02967 6.14e-233 - - - S - - - Psort location CytoplasmicMembrane, score
LPNANANF_02969 9.76e-33 - - - Q - - - Thioesterase domain
LPNANANF_02970 1.7e-297 yvkA - - P - - - -transporter
LPNANANF_02971 2.32e-144 yvkB - - K - - - Transcriptional regulator
LPNANANF_02972 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
LPNANANF_02973 2.59e-45 csbA - - S - - - protein conserved in bacteria
LPNANANF_02974 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
LPNANANF_02975 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
LPNANANF_02976 8.07e-44 yvkN - - - - - - -
LPNANANF_02977 4.87e-66 yvlA - - - - - - -
LPNANANF_02978 5.54e-219 yvlB - - S - - - Putative adhesin
LPNANANF_02979 4.01e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
LPNANANF_02980 7.66e-66 yvlD - - S ko:K08972 - ko00000 Membrane
LPNANANF_02981 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
LPNANANF_02982 8.92e-136 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
LPNANANF_02983 6.1e-171 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
LPNANANF_02984 1.82e-171 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LPNANANF_02985 5.29e-283 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
LPNANANF_02986 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LPNANANF_02987 6.15e-194 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LPNANANF_02988 1.57e-155 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
LPNANANF_02989 1.46e-111 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
LPNANANF_02990 5.06e-178 yvpB - - NU - - - protein conserved in bacteria
LPNANANF_02991 3.49e-269 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
LPNANANF_02992 7.47e-148 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
LPNANANF_02993 4.71e-300 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LPNANANF_02994 1.17e-137 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
LPNANANF_02995 3.29e-146 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LPNANANF_02996 6.55e-167 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LPNANANF_02997 1.14e-175 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
LPNANANF_02998 2.24e-141 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
LPNANANF_02999 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
LPNANANF_03000 1.33e-156 mprA3 - - T - - - COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LPNANANF_03001 3.35e-246 sasA - - T - - - Histidine kinase
LPNANANF_03002 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
LPNANANF_03003 4.08e-201 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
LPNANANF_03004 4.45e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
LPNANANF_03005 2.98e-112 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
LPNANANF_03006 2.45e-212 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
LPNANANF_03007 8.99e-226 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
LPNANANF_03008 5.16e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
LPNANANF_03009 3.23e-49 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
LPNANANF_03010 2.32e-182 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
LPNANANF_03011 2.26e-104 - - - M - - - Ribonuclease
LPNANANF_03012 3.42e-232 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LPNANANF_03013 4.41e-137 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
LPNANANF_03014 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
LPNANANF_03015 1.3e-69 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
LPNANANF_03016 2.66e-137 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
LPNANANF_03017 0.0 - - - EGP - - - Sugar (and other) transporter
LPNANANF_03018 2.11e-272 yraM - - S - - - PrpF protein
LPNANANF_03019 3.34e-210 yraN - - K - - - Transcriptional regulator
LPNANANF_03020 3.74e-136 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
LPNANANF_03021 9.47e-236 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
LPNANANF_03022 4.05e-285 rafB - - P ko:K02532 - ko00000,ko02000 LacY proton/sugar symporter
LPNANANF_03023 0.0 cscA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
LPNANANF_03025 1.31e-45 - - - - - - - -
LPNANANF_03026 9.54e-305 - - - I - - - Pfam Lipase (class 3)
LPNANANF_03029 6.09e-35 - - - S - - - Protein of unknown function (DUF1433)
LPNANANF_03031 2.47e-121 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
LPNANANF_03032 1.9e-119 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LPNANANF_03033 6.16e-145 yyaS - - S ko:K07149 - ko00000 Membrane
LPNANANF_03034 5.7e-127 ywjB - - H - - - RibD C-terminal domain
LPNANANF_03036 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
LPNANANF_03037 6.96e-100 - - - K ko:K19417 - ko00000,ko03000 transcriptional
LPNANANF_03038 4.76e-155 epsA - - M ko:K19420 - ko00000 biosynthesis protein
LPNANANF_03039 7.67e-152 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
LPNANANF_03040 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
LPNANANF_03041 1.75e-277 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
LPNANANF_03042 1.3e-204 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
LPNANANF_03043 6.06e-273 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
LPNANANF_03044 1.71e-262 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
LPNANANF_03045 2.55e-246 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
LPNANANF_03046 1.34e-259 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
LPNANANF_03047 8.95e-251 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
LPNANANF_03048 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LPNANANF_03049 6.44e-139 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
LPNANANF_03050 9.62e-73 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
LPNANANF_03051 6.4e-281 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
LPNANANF_03052 2.24e-237 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
LPNANANF_03053 4.01e-44 yvfG - - S - - - YvfG protein
LPNANANF_03054 6.84e-311 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
LPNANANF_03055 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
LPNANANF_03056 5.99e-154 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
LPNANANF_03057 4.54e-284 - - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LPNANANF_03058 2.14e-173 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
LPNANANF_03059 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
LPNANANF_03060 6.85e-171 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
LPNANANF_03061 1.37e-290 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
LPNANANF_03062 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
LPNANANF_03063 1.33e-195 gntR - - K - - - RpiR family transcriptional regulator
LPNANANF_03065 4.71e-275 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
LPNANANF_03066 4.29e-202 yvbV - - EG - - - EamA-like transporter family
LPNANANF_03067 1.51e-200 yvbU - - K - - - Transcriptional regulator
LPNANANF_03069 5.33e-243 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LPNANANF_03070 2.23e-260 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
LPNANANF_03071 0.0 araE - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LPNANANF_03073 2.95e-240 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
LPNANANF_03074 2.83e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LPNANANF_03075 3.98e-277 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
LPNANANF_03076 2.58e-177 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
LPNANANF_03077 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
LPNANANF_03078 9.69e-310 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LPNANANF_03079 3.43e-303 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
LPNANANF_03080 0.0 - 1.1.1.136 - M ko:K13015 ko00520,map00520 ko00000,ko00001,ko01000,ko01005 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LPNANANF_03081 1.14e-276 - 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
LPNANANF_03082 1.73e-219 arnA 4.2.1.46, 5.1.3.2 - M ko:K01710,ko:K01784 ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130 ko00000,ko00001,ko00002,ko01000 GDP-mannose 4,6 dehydratase
LPNANANF_03083 8.04e-296 - - - E - - - UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LPNANANF_03084 1.2e-186 - - - M - - - Protein involved in cellulose biosynthesis
LPNANANF_03085 8.29e-185 - - - C - - - WbqC-like protein family
LPNANANF_03086 1.9e-163 - - - S - - - GlcNAc-PI de-N-acetylase
LPNANANF_03087 1.39e-228 - - - - - - - -
LPNANANF_03088 1.81e-268 - - - EGP - - - Major facilitator Superfamily
LPNANANF_03089 1.29e-105 yvbK - - K - - - acetyltransferase
LPNANANF_03090 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
LPNANANF_03091 6.26e-156 yvbI - - M - - - Membrane
LPNANANF_03092 1.88e-135 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
LPNANANF_03093 1.18e-128 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
LPNANANF_03094 5.16e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
LPNANANF_03095 1.61e-144 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
LPNANANF_03096 3.79e-221 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
LPNANANF_03097 8.83e-141 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
LPNANANF_03098 2.81e-123 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
LPNANANF_03099 6.74e-267 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
LPNANANF_03100 9.74e-146 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
LPNANANF_03101 1.32e-221 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
LPNANANF_03102 2.09e-144 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
LPNANANF_03103 7.67e-162 spaF - - V ko:K01990,ko:K20459,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LPNANANF_03104 1.35e-154 spaE - - S ko:K20491 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
LPNANANF_03105 6.04e-173 spaG - - S ko:K20492 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
LPNANANF_03106 4.69e-159 spaR - - K ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
LPNANANF_03107 0.0 spaK 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
LPNANANF_03108 2.44e-69 yvaP - - K - - - transcriptional
LPNANANF_03109 1.01e-95 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
LPNANANF_03110 9.53e-93 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
LPNANANF_03111 1.64e-47 yvzC - - K - - - transcriptional
LPNANANF_03112 4.58e-36 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
LPNANANF_03113 1.7e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
LPNANANF_03114 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
LPNANANF_03115 4.85e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LPNANANF_03117 5.89e-66 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
LPNANANF_03118 3.23e-179 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
LPNANANF_03119 2.21e-203 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
LPNANANF_03120 3.16e-130 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
LPNANANF_03121 8.02e-166 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
LPNANANF_03122 6.11e-189 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
LPNANANF_03123 2.54e-157 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LPNANANF_03124 5.8e-156 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LPNANANF_03125 4.28e-179 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
LPNANANF_03126 4.31e-233 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LPNANANF_03127 2.39e-60 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
LPNANANF_03128 0.0 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LPNANANF_03129 1.03e-153 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LPNANANF_03130 8.25e-248 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
LPNANANF_03131 2.81e-64 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
LPNANANF_03132 1.88e-39 - - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Heavy-metal-associated domain
LPNANANF_03133 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
LPNANANF_03134 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
LPNANANF_03135 7.83e-139 bdbD - - O - - - Thioredoxin
LPNANANF_03136 7.48e-96 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
LPNANANF_03137 2.32e-191 - - - S - - - Metallo-peptidase family M12
LPNANANF_03138 6.36e-130 yvgT - - S - - - membrane
LPNANANF_03139 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
LPNANANF_03140 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LPNANANF_03141 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
LPNANANF_03142 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
LPNANANF_03143 1.38e-113 yvgO - - - - - - -
LPNANANF_03144 1.77e-200 yvgN - - S - - - reductase
LPNANANF_03145 1.56e-256 sagI - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
LPNANANF_03146 7.05e-249 sagH - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
LPNANANF_03147 1.66e-218 sagG - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
LPNANANF_03148 9.63e-250 - - - T - - - Histidine kinase
LPNANANF_03149 4.32e-148 yfiK - - K - - - Regulator
LPNANANF_03150 1.64e-126 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
LPNANANF_03151 1.95e-178 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
LPNANANF_03152 4.05e-213 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
LPNANANF_03153 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
LPNANANF_03154 1.01e-110 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
LPNANANF_03155 1.29e-20 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
LPNANANF_03156 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
LPNANANF_03157 2.48e-225 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LPNANANF_03158 3.29e-238 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LPNANANF_03159 3.22e-224 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LPNANANF_03160 9.78e-189 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
LPNANANF_03161 3.98e-87 yvrL - - S - - - Regulatory protein YrvL
LPNANANF_03162 8.91e-295 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
LPNANANF_03163 1.88e-21 - - - S - - - YvrJ protein family
LPNANANF_03164 6.51e-134 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
LPNANANF_03165 1.67e-50 - - - - - - - -
LPNANANF_03166 2.7e-172 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LPNANANF_03167 0.0 yvrG - - T - - - Histidine kinase
LPNANANF_03168 3.79e-219 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
LPNANANF_03169 8.63e-181 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
LPNANANF_03170 3.89e-214 yvrC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
LPNANANF_03171 8.89e-228 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LPNANANF_03172 1.65e-283 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
LPNANANF_03173 3.23e-133 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
LPNANANF_03174 6.8e-290 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
LPNANANF_03175 1.62e-68 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
LPNANANF_03176 2.79e-133 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
LPNANANF_03177 1.91e-181 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
LPNANANF_03178 8.56e-162 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
LPNANANF_03179 3.48e-247 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LPNANANF_03180 8.35e-139 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LPNANANF_03181 2.93e-260 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
LPNANANF_03182 6.91e-241 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
LPNANANF_03183 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
LPNANANF_03184 1.83e-33 - - - S - - - Protein of unknown function (DUF3970)
LPNANANF_03185 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
LPNANANF_03186 1.8e-200 yuxN - - K - - - Transcriptional regulator
LPNANANF_03187 2.68e-32 - - - - - - - -
LPNANANF_03188 0.0 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LPNANANF_03189 1.29e-163 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LPNANANF_03190 6.24e-304 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LPNANANF_03191 6.84e-102 dps2 - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
LPNANANF_03192 6.38e-196 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
LPNANANF_03193 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
LPNANANF_03194 7.61e-60 - - - S - - - YusW-like protein
LPNANANF_03195 9.06e-193 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
LPNANANF_03196 2.15e-52 yusU - - S - - - Protein of unknown function (DUF2573)
LPNANANF_03197 1.4e-239 apbA 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LPNANANF_03198 4.14e-176 - 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
LPNANANF_03199 8.42e-204 - - - K - - - Transcriptional regulator
LPNANANF_03200 0.0 yusP - - P - - - Major facilitator superfamily
LPNANANF_03201 7.93e-91 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
LPNANANF_03202 5.21e-71 yusN - - M - - - Coat F domain
LPNANANF_03203 3.2e-58 - - - - - - - -
LPNANANF_03204 8.5e-212 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
LPNANANF_03205 5.98e-11 - - - S - - - YuzL-like protein
LPNANANF_03206 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
LPNANANF_03207 7.74e-278 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
LPNANANF_03208 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
LPNANANF_03209 7.13e-84 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
LPNANANF_03210 4.16e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
LPNANANF_03211 3.1e-55 yusG - - S - - - Protein of unknown function (DUF2553)
LPNANANF_03212 8.85e-82 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
LPNANANF_03213 1.64e-72 yusE - - CO - - - Thioredoxin
LPNANANF_03214 1.29e-76 yusD - - S - - - SCP-2 sterol transfer family
LPNANANF_03215 3.71e-237 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LPNANANF_03216 8.47e-138 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
LPNANANF_03217 9e-187 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
LPNANANF_03218 5.13e-84 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LPNANANF_03219 3.82e-183 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
LPNANANF_03220 1.23e-311 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
LPNANANF_03221 2.31e-298 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LPNANANF_03222 1.26e-100 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
LPNANANF_03223 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
LPNANANF_03224 2.52e-201 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
LPNANANF_03225 1.07e-104 yncE - - S - - - Protein of unknown function (DUF2691)
LPNANANF_03226 7.62e-166 - - - Q - - - ubiE/COQ5 methyltransferase family
LPNANANF_03227 5.87e-256 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
LPNANANF_03228 5.74e-86 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
LPNANANF_03230 2.24e-236 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
LPNANANF_03231 4.28e-312 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
LPNANANF_03232 3.04e-202 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LPNANANF_03233 8.47e-208 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
LPNANANF_03234 2.63e-206 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
LPNANANF_03235 1.19e-172 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
LPNANANF_03236 1.07e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LPNANANF_03237 4.77e-216 bsn - - L - - - Ribonuclease
LPNANANF_03238 1.34e-296 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
LPNANANF_03239 8.46e-302 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
LPNANANF_03240 3.01e-274 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
LPNANANF_03242 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
LPNANANF_03243 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
LPNANANF_03244 3.04e-80 - - - S - - - phosphoglycolate phosphatase activity
LPNANANF_03245 1.8e-217 yunF - - S - - - Protein of unknown function DUF72
LPNANANF_03246 3.01e-186 yunE - - S ko:K07090 - ko00000 membrane transporter protein
LPNANANF_03247 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
LPNANANF_03248 1.12e-166 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
LPNANANF_03249 4.77e-250 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
LPNANANF_03250 3.92e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LPNANANF_03251 3.71e-62 yutD - - S - - - protein conserved in bacteria
LPNANANF_03252 1.55e-95 yutE - - S - - - Protein of unknown function DUF86
LPNANANF_03253 1.01e-180 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
LPNANANF_03254 1.5e-109 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
LPNANANF_03255 1.55e-250 yutH - - S - - - Spore coat protein
LPNANANF_03256 8.26e-308 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
LPNANANF_03257 4.63e-251 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LPNANANF_03258 7.89e-216 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
LPNANANF_03259 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
LPNANANF_03260 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
LPNANANF_03261 2.71e-72 yuzD - - S - - - protein conserved in bacteria
LPNANANF_03262 8.47e-266 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
LPNANANF_03263 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
LPNANANF_03264 1.49e-273 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LPNANANF_03265 4.55e-207 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LPNANANF_03266 1.38e-82 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
LPNANANF_03267 1.82e-177 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
LPNANANF_03268 2.68e-22 - - - K - - - helix_turn_helix, mercury resistance
LPNANANF_03270 5.3e-44 - - - S - - - Bacteriocin class IId cyclical uberolysin-like
LPNANANF_03272 6.54e-157 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
LPNANANF_03273 4.17e-93 - - - CP - - - Membrane
LPNANANF_03274 5.68e-40 - - - - - - - -
LPNANANF_03275 1.11e-235 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
LPNANANF_03277 4.19e-238 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
LPNANANF_03278 5.44e-297 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
LPNANANF_03279 2.45e-45 yuiB - - S - - - Putative membrane protein
LPNANANF_03280 1.7e-153 yuiC - - S - - - protein conserved in bacteria
LPNANANF_03281 8.29e-100 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
LPNANANF_03282 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LPNANANF_03283 8.19e-276 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
LPNANANF_03284 5.29e-131 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
LPNANANF_03285 1.27e-152 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
LPNANANF_03286 3.47e-209 eSD - - S ko:K07017 - ko00000 Putative esterase
LPNANANF_03287 8.62e-172 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
LPNANANF_03288 3.07e-283 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
LPNANANF_03289 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
LPNANANF_03290 1.13e-219 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
LPNANANF_03291 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LPNANANF_03292 1.91e-46 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
LPNANANF_03293 3.06e-171 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
LPNANANF_03294 5.7e-261 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
LPNANANF_03295 2.02e-289 yukF - - QT - - - Transcriptional regulator
LPNANANF_03296 2.36e-61 yukE - - S - - - Belongs to the WXG100 family
LPNANANF_03297 5.28e-53 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
LPNANANF_03298 1.13e-275 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
LPNANANF_03299 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
LPNANANF_03300 0.0 yueB - - S - - - type VII secretion protein EsaA
LPNANANF_03301 5.41e-100 yueC - - S - - - Family of unknown function (DUF5383)
LPNANANF_03302 5.85e-169 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LPNANANF_03303 1.57e-124 yueE - - S ko:K06950 - ko00000 phosphohydrolase
LPNANANF_03304 2.81e-31 - - - S - - - Protein of unknown function (DUF2642)
LPNANANF_03305 2.67e-238 yueF - - S - - - transporter activity
LPNANANF_03306 6.33e-46 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
LPNANANF_03307 5.46e-51 yueH - - S - - - YueH-like protein
LPNANANF_03308 1.87e-88 yueI - - S - - - Protein of unknown function (DUF1694)
LPNANANF_03309 8.02e-135 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
LPNANANF_03310 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LPNANANF_03311 3.97e-295 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
LPNANANF_03312 7.31e-68 yuzC - - - - - - -
LPNANANF_03313 2.66e-11 - - - S - - - DegQ (SacQ) family
LPNANANF_03314 3.65e-124 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Belongs to the FPP GGPP synthase family
LPNANANF_03316 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LPNANANF_03317 8.07e-148 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LPNANANF_03318 4e-83 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
LPNANANF_03319 1.21e-78 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
LPNANANF_03320 1.1e-51 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LPNANANF_03321 1.23e-101 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LPNANANF_03322 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LPNANANF_03323 1.47e-67 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LPNANANF_03324 6.3e-90 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LPNANANF_03325 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
LPNANANF_03327 4.39e-218 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
LPNANANF_03328 5.48e-238 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
LPNANANF_03329 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LPNANANF_03330 4.98e-250 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
LPNANANF_03331 6.58e-162 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
LPNANANF_03332 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
LPNANANF_03333 9.25e-101 yufK - - S - - - Family of unknown function (DUF5366)
LPNANANF_03334 5.29e-95 yuxK - - S - - - protein conserved in bacteria
LPNANANF_03335 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
LPNANANF_03336 1.84e-263 yuxJ - - EGP - - - Major facilitator superfamily
LPNANANF_03337 2.64e-153 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
LPNANANF_03338 4.23e-17 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
LPNANANF_03339 8.24e-289 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LPNANANF_03340 1.92e-285 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
LPNANANF_03341 4.25e-55 yugE - - S - - - Domain of unknown function (DUF1871)
LPNANANF_03342 6.68e-199 yugF - - I - - - Hydrolase
LPNANANF_03343 3.75e-109 alaR - - K - - - Transcriptional regulator
LPNANANF_03344 1.68e-266 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
LPNANANF_03345 2.04e-82 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
LPNANANF_03346 3.14e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
LPNANANF_03347 9.52e-286 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
LPNANANF_03348 1.37e-291 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
LPNANANF_03349 1.77e-151 ycaC - - Q - - - Isochorismatase family
LPNANANF_03350 3.94e-133 - - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
LPNANANF_03351 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
LPNANANF_03353 2.09e-95 yugN - - S - - - YugN-like family
LPNANANF_03354 4.84e-231 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
LPNANANF_03355 4.93e-35 mstX - - S - - - Membrane-integrating protein Mistic
LPNANANF_03357 1.95e-149 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
LPNANANF_03358 6.63e-296 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
LPNANANF_03359 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
LPNANANF_03360 5.24e-101 yugU - - S - - - Uncharacterised protein family UPF0047
LPNANANF_03361 4.93e-243 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
LPNANANF_03362 1.61e-55 - - - - - - - -
LPNANANF_03363 3.68e-178 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
LPNANANF_03364 7.61e-315 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
LPNANANF_03365 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
LPNANANF_03366 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
LPNANANF_03367 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
LPNANANF_03368 6.95e-127 yraA 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 DJ-1/PfpI family
LPNANANF_03369 1.29e-235 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
LPNANANF_03370 9.96e-251 yubA - - S - - - transporter activity
LPNANANF_03371 6.56e-187 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
LPNANANF_03373 6.21e-68 yjcN - - - - - - -
LPNANANF_03374 7.53e-157 - - - G - - - Cupin
LPNANANF_03375 2.07e-282 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LPNANANF_03376 2.58e-191 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LPNANANF_03377 1.06e-156 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
LPNANANF_03378 2.03e-122 yuaB - - - - - - -
LPNANANF_03379 7.09e-125 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
LPNANANF_03380 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
LPNANANF_03381 1.01e-289 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
LPNANANF_03382 1.37e-140 - - - S - - - MOSC domain
LPNANANF_03383 2.45e-103 yuaE - - S - - - DinB superfamily
LPNANANF_03384 1.13e-108 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
LPNANANF_03385 2.65e-278 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
LPNANANF_03386 1.71e-125 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
LPNANANF_03387 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
LPNANANF_03388 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
LPNANANF_03389 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
LPNANANF_03393 0.0 iolT - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LPNANANF_03394 3.3e-236 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
LPNANANF_03395 2.41e-111 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
LPNANANF_03396 4.41e-214 ydhU - - P ko:K07217 - ko00000 Catalase
LPNANANF_03397 0.0 ybeC - - E - - - amino acid
LPNANANF_03398 1.48e-135 yvdT_1 - - K - - - Transcriptional regulator
LPNANANF_03399 4.48e-67 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
LPNANANF_03400 1.48e-65 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
LPNANANF_03401 1.23e-276 yycB1 - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
LPNANANF_03402 1.88e-153 - - - K ko:K05799 - ko00000,ko03000 FCD
LPNANANF_03403 7.17e-172 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
LPNANANF_03404 9.11e-247 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
LPNANANF_03405 1.75e-127 ydhK - - M - - - Protein of unknown function (DUF1541)
LPNANANF_03407 0.0 pbpE - - V - - - Beta-lactamase
LPNANANF_03410 3.92e-290 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
LPNANANF_03411 2.29e-154 ydhC - - K - - - FCD
LPNANANF_03412 2.83e-212 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
LPNANANF_03413 4.28e-134 - 3.1.1.24 - S ko:K01055 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Alpha/beta hydrolase family
LPNANANF_03414 3.19e-145 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
LPNANANF_03415 1.8e-191 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
LPNANANF_03416 4.85e-192 bltR - - K - - - helix_turn_helix, mercury resistance
LPNANANF_03417 4.35e-108 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
LPNANANF_03418 2.58e-157 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
LPNANANF_03419 6.42e-200 - - - K - - - Helix-turn-helix XRE-family like proteins
LPNANANF_03420 9.23e-287 fabF_1 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LPNANANF_03421 1.36e-268 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
LPNANANF_03422 1.62e-249 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
LPNANANF_03423 1.74e-191 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
LPNANANF_03424 5.28e-127 ynaD - - J - - - Acetyltransferase (GNAT) domain
LPNANANF_03425 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
LPNANANF_03426 2.4e-171 puuD - - S ko:K07010 - ko00000,ko01002 Peptidase C26
LPNANANF_03427 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
LPNANANF_03428 9.01e-139 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LPNANANF_03429 4.04e-274 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LPNANANF_03430 3.45e-49 yraG - - - ko:K06440 - ko00000 -
LPNANANF_03431 8.22e-85 yraF - - M - - - Spore coat protein
LPNANANF_03432 4.33e-282 adhB 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
LPNANANF_03433 1.69e-33 yraE - - - ko:K06440 - ko00000 -
LPNANANF_03434 1.2e-64 yraD - - M ko:K06439 - ko00000 Spore coat protein
LPNANANF_03435 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LPNANANF_03436 8.71e-201 ydeK - - EG - - - -transporter
LPNANANF_03437 1.4e-131 ydeS - - K - - - Transcriptional regulator
LPNANANF_03438 1.85e-251 ydeR - - EGP - - - Uncharacterised MFS-type transporter YbfB
LPNANANF_03440 3.59e-147 paiB - - K ko:K07734 - ko00000,ko03000 Transcriptional regulator
LPNANANF_03441 0.0 - - - K ko:K00375 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
LPNANANF_03442 4.77e-289 nhaC_1 - - C - - - antiporter
LPNANANF_03443 7.29e-87 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
LPNANANF_03444 5.46e-259 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
LPNANANF_03445 4.35e-214 - - - S - - - Sodium Bile acid symporter family
LPNANANF_03446 2.05e-69 ydeH - - - - - - -
LPNANANF_03447 5.16e-248 cfr 2.1.1.224 - J ko:K15632 - ko00000,ko01000,ko01504,ko03009 Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
LPNANANF_03449 4.68e-190 dapA7 4.3.3.7 - EM ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Dihydrodipicolinate synthetase family
LPNANANF_03450 3.35e-113 ykkA - - S - - - Protein of unknown function (DUF664)
LPNANANF_03451 3.3e-131 yrkC - - G - - - Cupin domain
LPNANANF_03453 7.72e-257 trkA - - P ko:K07222 - ko00000 Oxidoreductase
LPNANANF_03454 9.22e-217 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
LPNANANF_03455 0.0 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
LPNANANF_03458 2.04e-82 - - - G - - - Cupin domain
LPNANANF_03459 6.08e-102 - - - S - - - DinB superfamily
LPNANANF_03460 2.06e-233 - - - S - - - Patatin-like phospholipase
LPNANANF_03461 2.24e-299 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
LPNANANF_03462 4.24e-216 ybfA - - K - - - FR47-like protein
LPNANANF_03463 6.75e-67 - - - K - - - Transcriptional regulator PadR-like family
LPNANANF_03464 8.94e-135 - - - S - - - Protein of unknown function (DUF2812)
LPNANANF_03465 1.29e-159 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
LPNANANF_03466 2.51e-103 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
LPNANANF_03467 3.87e-42 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
LPNANANF_03468 3.74e-242 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
LPNANANF_03469 1.32e-221 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
LPNANANF_03470 4.73e-146 - - - C ko:K07124 - ko00000 Enoyl-(Acyl carrier protein) reductase
LPNANANF_03471 2.06e-116 - - - K ko:K16137 - ko00000,ko03000 Bacterial regulatory proteins, tetR family
LPNANANF_03473 6.37e-144 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
LPNANANF_03474 4.07e-97 ywnA - - K - - - Transcriptional regulator
LPNANANF_03475 1.59e-85 - - - S - - - YjbR
LPNANANF_03476 4.48e-98 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
LPNANANF_03477 2e-93 yddJ - - S - - - Domain of unknown function with cystatin-like fold (DUF4467)
LPNANANF_03478 5.16e-66 ohrR - - K - - - Transcriptional regulator
LPNANANF_03479 0.0 - - - EGP ko:K03761,ko:K03762 - ko00000,ko02000 Transporter
LPNANANF_03480 1.35e-124 yrkL - - S ko:K11748 - ko00000,ko02000 Flavodoxin-like fold
LPNANANF_03489 2.88e-74 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
LPNANANF_03490 1.78e-21 - - - - - - - -
LPNANANF_03491 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
LPNANANF_03492 5.75e-141 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
LPNANANF_03493 1.14e-180 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LPNANANF_03494 7.1e-111 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
LPNANANF_03495 9.77e-71 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
LPNANANF_03496 1.25e-241 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
LPNANANF_03497 1.73e-89 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
LPNANANF_03498 6.28e-75 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
LPNANANF_03499 1.05e-186 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
LPNANANF_03500 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
LPNANANF_03501 6.68e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
LPNANANF_03502 2.81e-279 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LPNANANF_03503 1.57e-235 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
LPNANANF_03504 1.09e-75 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
LPNANANF_03505 1.47e-138 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
LPNANANF_03506 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
LPNANANF_03507 6.83e-109 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
LPNANANF_03508 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
LPNANANF_03509 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
LPNANANF_03510 2.16e-258 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
LPNANANF_03511 2.25e-74 ydbP - - CO - - - Thioredoxin
LPNANANF_03512 5.46e-158 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LPNANANF_03513 1.89e-13 - - - S - - - Fur-regulated basic protein A
LPNANANF_03514 1.13e-15 - - - S - - - Fur-regulated basic protein B
LPNANANF_03515 4.53e-263 ydbM - - I - - - acyl-CoA dehydrogenase
LPNANANF_03516 8.96e-68 ydbL - - - - - - -
LPNANANF_03517 2.44e-167 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
LPNANANF_03518 1.67e-221 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LPNANANF_03519 8.61e-231 ydbI - - S - - - AI-2E family transporter
LPNANANF_03520 9.2e-286 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LPNANANF_03521 1.5e-152 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
LPNANANF_03522 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
LPNANANF_03523 6.33e-254 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
LPNANANF_03524 3.87e-198 ydbD - - P ko:K07217 - ko00000 Catalase
LPNANANF_03525 3.67e-38 ydbC - - S - - - Domain of unknown function (DUF4937
LPNANANF_03526 5.34e-78 ydbB - - G - - - Cupin domain
LPNANANF_03527 1.24e-10 gsiB - - S ko:K06884 - ko00000 general stress protein
LPNANANF_03528 9.32e-183 ydbA - - P - - - EcsC protein family
LPNANANF_03529 2.87e-71 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
LPNANANF_03530 5.32e-94 yvaD - - S - - - Family of unknown function (DUF5360)
LPNANANF_03531 1.95e-45 ydaT - - - - - - -
LPNANANF_03533 1.87e-288 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
LPNANANF_03534 7.45e-54 - - - - - - - -
LPNANANF_03535 1.65e-127 - - - - - - - -
LPNANANF_03536 2.95e-113 - - - - - - - -
LPNANANF_03538 3.82e-12 - - - - - - - -
LPNANANF_03540 4.94e-267 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
LPNANANF_03541 3.67e-84 - - - - - - - -
LPNANANF_03542 4.36e-110 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
LPNANANF_03543 7.61e-31 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
LPNANANF_03544 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
LPNANANF_03545 1.21e-94 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
LPNANANF_03546 0.0 ydaO - - E - - - amino acid
LPNANANF_03547 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
LPNANANF_03548 1.7e-298 ydaM - - M - - - Glycosyl transferase family group 2
LPNANANF_03549 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
LPNANANF_03550 1.54e-188 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
LPNANANF_03551 6.91e-259 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
LPNANANF_03552 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LPNANANF_03553 3.25e-97 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
LPNANANF_03554 6.54e-63 ydzA - - EGP - - - Domain of unknown function (DUF3817)
LPNANANF_03555 1.26e-176 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
LPNANANF_03556 7.45e-101 ydaG - - S - - - general stress protein
LPNANANF_03557 9.91e-150 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
LPNANANF_03558 1.86e-123 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
LPNANANF_03559 9.37e-208 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LPNANANF_03560 0.0 ydaB - - IQ - - - acyl-CoA ligase
LPNANANF_03561 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
LPNANANF_03562 3e-220 ycsN - - S - - - Oxidoreductase
LPNANANF_03563 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
LPNANANF_03564 5.95e-75 yczJ - - S - - - biosynthesis
LPNANANF_03566 6.66e-151 ycsK - - E - - - anatomical structure formation involved in morphogenesis
LPNANANF_03567 8.04e-168 kipR - - K - - - Transcriptional regulator
LPNANANF_03568 6.97e-240 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
LPNANANF_03569 4.66e-175 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
LPNANANF_03570 1.34e-189 ycsI - - S - - - Belongs to the D-glutamate cyclase family
LPNANANF_03571 2.66e-271 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
LPNANANF_03572 2.49e-180 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
LPNANANF_03573 2.69e-177 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
LPNANANF_03575 6.81e-86 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
LPNANANF_03576 4.21e-266 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
LPNANANF_03577 4.81e-94 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
LPNANANF_03578 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
LPNANANF_03579 1.59e-71 - - - - - - - -
LPNANANF_03580 4.26e-138 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
LPNANANF_03581 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
LPNANANF_03582 1.44e-129 ycnI - - S - - - protein conserved in bacteria
LPNANANF_03583 4.85e-186 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LPNANANF_03584 8.27e-191 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
LPNANANF_03585 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LPNANANF_03586 3.09e-287 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LPNANANF_03587 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LPNANANF_03588 2.27e-69 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
LPNANANF_03589 3.39e-60 ycnE - - S - - - Monooxygenase
LPNANANF_03590 9.75e-175 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Nitroreductase family
LPNANANF_03591 2.12e-195 ycnC - - K - - - Transcriptional regulator
LPNANANF_03592 1.19e-314 ycnB - - EGP - - - the major facilitator superfamily
LPNANANF_03593 3.95e-223 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
LPNANANF_03594 4.63e-175 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LPNANANF_03595 1.4e-212 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LPNANANF_03596 7.78e-211 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LPNANANF_03597 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
LPNANANF_03600 5.98e-100 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
LPNANANF_03601 0.0 yclK - - T - - - COG0642 Signal transduction histidine kinase
LPNANANF_03602 7.47e-164 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LPNANANF_03603 2.58e-311 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
LPNANANF_03604 4.65e-158 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
LPNANANF_03605 0.0 yxeQ - - S - - - MmgE/PrpD family
LPNANANF_03606 1.89e-274 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
LPNANANF_03607 2.28e-169 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LPNANANF_03608 1.49e-148 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
LPNANANF_03609 6.34e-183 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
LPNANANF_03610 4.43e-120 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LPNANANF_03611 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LPNANANF_03612 7.58e-248 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
LPNANANF_03613 8.08e-300 gerKC - - S ko:K06297 - ko00000 spore germination
LPNANANF_03614 0.0 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
LPNANANF_03616 0.0 yclG - - M - - - Pectate lyase superfamily protein
LPNANANF_03617 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
LPNANANF_03618 1.13e-98 yclD - - - - - - -
LPNANANF_03619 2.83e-52 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
LPNANANF_03620 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
LPNANANF_03621 5.7e-129 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
LPNANANF_03622 9.88e-205 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
LPNANANF_03623 2.8e-187 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
LPNANANF_03624 8.67e-154 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
LPNANANF_03625 3.24e-168 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
LPNANANF_03626 3.11e-144 yczE - - S ko:K07149 - ko00000 membrane
LPNANANF_03627 3.57e-165 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
LPNANANF_03628 5.72e-316 ycxD - - K - - - GntR family transcriptional regulator
LPNANANF_03629 3.9e-217 ycxC - - EG - - - EamA-like transporter family
LPNANANF_03630 1.57e-83 - - - S - - - YcxB-like protein
LPNANANF_03631 9.53e-317 - - - E - - - Aminotransferase class I and II
LPNANANF_03632 3.56e-179 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
LPNANANF_03633 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
LPNANANF_03634 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LPNANANF_03635 5.24e-182 pdaB - - G - - - Polysaccharide deacetylase
LPNANANF_03636 1.25e-134 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
LPNANANF_03637 1.95e-102 gerD - - - ko:K06294 - ko00000 -
LPNANANF_03638 1.28e-253 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
LPNANANF_03639 2.31e-172 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
LPNANANF_03640 1.31e-102 ybaK - - S - - - Protein of unknown function (DUF2521)
LPNANANF_03641 3.68e-107 yizA - - S - - - Damage-inducible protein DinB
LPNANANF_03642 1.76e-185 ybaJ - - Q - - - Methyltransferase domain
LPNANANF_03643 1.49e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
LPNANANF_03644 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LPNANANF_03645 1.63e-177 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
LPNANANF_03646 7.93e-178 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LPNANANF_03647 2.09e-191 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LPNANANF_03648 3.05e-199 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LPNANANF_03649 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
LPNANANF_03650 4.94e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LPNANANF_03651 4.61e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LPNANANF_03652 1.54e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LPNANANF_03653 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
LPNANANF_03654 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LPNANANF_03655 2.32e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
LPNANANF_03656 4.34e-158 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
LPNANANF_03657 1.34e-296 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
LPNANANF_03658 2.1e-94 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
LPNANANF_03659 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
LPNANANF_03660 4.54e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LPNANANF_03661 8.29e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LPNANANF_03662 3.14e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LPNANANF_03663 1.08e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LPNANANF_03664 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LPNANANF_03665 5.43e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LPNANANF_03666 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LPNANANF_03667 2.55e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LPNANANF_03668 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LPNANANF_03669 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
LPNANANF_03670 1.38e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LPNANANF_03671 1.69e-151 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LPNANANF_03672 1.08e-69 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LPNANANF_03673 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LPNANANF_03674 9.5e-201 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LPNANANF_03675 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
LPNANANF_03676 3.68e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
LPNANANF_03677 1.77e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LPNANANF_03678 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
LPNANANF_03679 6.69e-239 ybaC - - S - - - Alpha/beta hydrolase family
LPNANANF_03680 2.35e-286 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LPNANANF_03681 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LPNANANF_03682 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
LPNANANF_03683 9.47e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LPNANANF_03684 5.94e-46 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
LPNANANF_03685 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LPNANANF_03686 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LPNANANF_03687 1.2e-138 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
LPNANANF_03688 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
LPNANANF_03689 4.03e-104 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LPNANANF_03690 8.66e-161 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
LPNANANF_03691 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LPNANANF_03692 1.28e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
LPNANANF_03693 3.77e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
LPNANANF_03694 1.39e-150 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
LPNANANF_03695 4.03e-115 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
LPNANANF_03696 8.3e-172 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LPNANANF_03697 4.11e-95 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LPNANANF_03698 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
LPNANANF_03699 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
LPNANANF_03700 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LPNANANF_03701 3.02e-111 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
LPNANANF_03702 5.01e-160 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
LPNANANF_03703 8.6e-251 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
LPNANANF_03704 7.66e-251 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
LPNANANF_03705 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LPNANANF_03706 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
LPNANANF_03707 1.9e-257 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
LPNANANF_03708 6.61e-83 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
LPNANANF_03709 2.14e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
LPNANANF_03710 4.46e-42 csfB - - S - - - Inhibitor of sigma-G Gin
LPNANANF_03711 1.19e-135 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
LPNANANF_03712 1.46e-245 yaaN - - P - - - Belongs to the TelA family
LPNANANF_03713 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
LPNANANF_03714 1.9e-145 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LPNANANF_03715 5.03e-73 yaaQ - - S - - - protein conserved in bacteria
LPNANANF_03716 2.98e-94 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
LPNANANF_03717 6.37e-232 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
LPNANANF_03718 9e-189 yaaT - - S - - - stage 0 sporulation protein
LPNANANF_03719 3.08e-56 yabA - - L - - - Involved in initiation control of chromosome replication
LPNANANF_03720 3.99e-178 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
LPNANANF_03721 1.64e-62 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
LPNANANF_03722 2.34e-209 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LPNANANF_03723 6.14e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
LPNANANF_03724 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LPNANANF_03725 1.5e-184 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
LPNANANF_03726 2.04e-309 yabE - - T - - - protein conserved in bacteria
LPNANANF_03727 7.62e-126 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LPNANANF_03728 4.86e-202 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
LPNANANF_03729 5.75e-209 yabG - - S ko:K06436 - ko00000 peptidase
LPNANANF_03730 3.08e-52 veg - - S - - - protein conserved in bacteria
LPNANANF_03731 7.31e-38 sspF - - S ko:K06423 - ko00000 DNA topological change
LPNANANF_03732 2.73e-206 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LPNANANF_03733 5.67e-197 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
LPNANANF_03734 7.5e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
LPNANANF_03735 4.23e-64 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
LPNANANF_03736 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LPNANANF_03737 2.47e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LPNANANF_03738 2.15e-137 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LPNANANF_03739 1.74e-136 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
LPNANANF_03740 1.1e-54 yabK - - S - - - Peptide ABC transporter permease
LPNANANF_03741 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LPNANANF_03742 8.02e-119 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
LPNANANF_03743 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LPNANANF_03744 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
LPNANANF_03745 8.51e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
LPNANANF_03746 5.47e-66 yabP - - S - - - Sporulation protein YabP
LPNANANF_03747 3.37e-134 yabQ - - S - - - spore cortex biosynthesis protein
LPNANANF_03748 1.7e-74 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
LPNANANF_03749 3.54e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
LPNANANF_03752 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
LPNANANF_03753 8.92e-165 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
LPNANANF_03754 3.3e-236 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
LPNANANF_03755 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
LPNANANF_03756 1.05e-119 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
LPNANANF_03757 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LPNANANF_03758 8.14e-178 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LPNANANF_03759 3.19e-206 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LPNANANF_03760 1.14e-197 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
LPNANANF_03761 8.88e-217 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
LPNANANF_03762 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LPNANANF_03763 5.35e-139 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
LPNANANF_03764 4.9e-207 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
LPNANANF_03765 3.19e-203 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LPNANANF_03766 1.13e-81 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LPNANANF_03767 1.12e-115 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LPNANANF_03768 6.1e-40 yazB - - K - - - transcriptional
LPNANANF_03769 5.32e-242 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LPNANANF_03770 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)