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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HFBHIDMB_00003	3.24e-84	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HFBHIDMB_00004	1.09e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HFBHIDMB_00005	2.45e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
HFBHIDMB_00006	2.92e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HFBHIDMB_00007	8.69e-181	pdaB	-	-	G	-	-	-	Polysaccharide deacetylase
HFBHIDMB_00008	5.95e-133	kbaA	-	-	S	ko:K06349	-	ko00000	Involved in the activation of the KinB signaling pathway of sporulation
HFBHIDMB_00009	1.48e-122	gerD	-	-	-	ko:K06294	-	ko00000	-
HFBHIDMB_00010	1.1e-255	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HFBHIDMB_00011	1.23e-167	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
HFBHIDMB_00012	1.47e-90	ybaK	-	-	S	-	-	-	Protein of unknown function (DUF2521)
HFBHIDMB_00013	1.69e-183	ybaJ	-	-	Q	-	-	-	Methyltransferase domain
HFBHIDMB_00014	4.28e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HFBHIDMB_00015	1.13e-102	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HFBHIDMB_00016	4.33e-182	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HFBHIDMB_00017	1.6e-177	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HFBHIDMB_00018	6.34e-196	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HFBHIDMB_00019	7.5e-200	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HFBHIDMB_00020	4.27e-77	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HFBHIDMB_00021	2.11e-66	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
HFBHIDMB_00022	3.64e-158	ynaC	-	-	-	-	-	-	-
HFBHIDMB_00023	8.25e-61	-	-	-	S	-	-	-	Restriction endonuclease
HFBHIDMB_00024	3.17e-32	-	-	-	-	-	-	-	-
HFBHIDMB_00025	1.14e-20	-	-	-	S	-	-	-	peptidoglycan catabolic process
HFBHIDMB_00027	9.06e-82	-	-	-	-	-	-	-	-
HFBHIDMB_00029	2.3e-41	-	-	-	-	-	-	-	-
HFBHIDMB_00030	2.53e-23	-	-	-	-	-	-	-	-
HFBHIDMB_00035	2.21e-56	-	-	-	-	-	-	-	-
HFBHIDMB_00036	6.48e-255	-	-	-	I	-	-	-	Pfam Lipase (class 3)
HFBHIDMB_00037	1.06e-232	yaaC	-	-	S	-	-	-	YaaC-like Protein
HFBHIDMB_00038	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HFBHIDMB_00039	3.75e-316	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HFBHIDMB_00040	3.7e-202	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HFBHIDMB_00041	1.66e-138	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HFBHIDMB_00042	9.79e-296	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HFBHIDMB_00044	3.72e-159	dck	2.7.1.74, 2.7.1.76	-	F	ko:K15519	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko01000	Deoxycytidine kinase
HFBHIDMB_00045	5.73e-149	dgk	2.7.1.113	-	F	ko:K15518	ko00230,map00230	ko00000,ko00001,ko01000	Deoxyguanosine kinase
HFBHIDMB_00046	5.18e-276	yaaH	-	-	M	ko:K06306	-	ko00000	Glycoside Hydrolase Family
HFBHIDMB_00047	2.3e-124	yaaI	-	-	Q	-	-	-	COG1335 Amidases related to nicotinamidase
HFBHIDMB_00048	1.05e-108	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HFBHIDMB_00049	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HFBHIDMB_00050	8.75e-55	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HFBHIDMB_00051	3.47e-141	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HFBHIDMB_00052	1.55e-42	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HFBHIDMB_00053	5.3e-49	bofA	-	-	S	ko:K06317	-	ko00000	Sigma-K factor-processing regulatory protein BofA
HFBHIDMB_00054	1.36e-63	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HFBHIDMB_00055	3.68e-112	ydiB	-	-	S	ko:K06925	-	ko00000,ko03016	ATPase or kinase
HFBHIDMB_00056	3.98e-160	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	COG1214 Inactive homolog of metal-dependent proteases
HFBHIDMB_00057	8.72e-100	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
HFBHIDMB_00058	2.36e-74	mcsA	-	-	S	ko:K19411	-	ko00000	protein with conserved CXXC pairs
HFBHIDMB_00059	7.74e-257	mcsB	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HFBHIDMB_00060	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
HFBHIDMB_00061	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HFBHIDMB_00062	3.8e-251	disA	2.7.7.85	-	L	ko:K07067	-	ko00000,ko01000	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HFBHIDMB_00063	2.57e-252	yacL	-	-	S	-	-	-	COG4956 Integral membrane protein (PIN domain superfamily)
HFBHIDMB_00064	4.29e-161	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HFBHIDMB_00065	6.35e-113	ispF	2.7.7.60, 4.6.1.12	-	I	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HFBHIDMB_00066	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HFBHIDMB_00067	1.91e-152	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase
HFBHIDMB_00068	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HFBHIDMB_00069	2.04e-95	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HFBHIDMB_00070	3.52e-173	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HFBHIDMB_00071	3.31e-114	yacP	-	-	S	ko:K06962	-	ko00000	RNA-binding protein containing a PIN domain
HFBHIDMB_00072	3.27e-149	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
HFBHIDMB_00073	2.65e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HFBHIDMB_00074	1.37e-124	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HFBHIDMB_00075	3.4e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HFBHIDMB_00076	1.82e-162	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HFBHIDMB_00077	5.72e-104	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HFBHIDMB_00078	2.84e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HFBHIDMB_00079	5.1e-140	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
HFBHIDMB_00080	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HFBHIDMB_00081	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HFBHIDMB_00082	1.99e-44	rplGB	-	-	J	ko:K07590	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the eukaryotic ribosomal protein eL8 family
HFBHIDMB_00083	6.67e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HFBHIDMB_00084	4.85e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HFBHIDMB_00085	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HFBHIDMB_00086	2.01e-287	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HFBHIDMB_00087	2.13e-229	ybaC	-	-	S	-	-	-	Alpha/beta hydrolase family
HFBHIDMB_00088	2.58e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HFBHIDMB_00089	7.2e-144	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HFBHIDMB_00090	7.98e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HFBHIDMB_00091	3.27e-58	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HFBHIDMB_00092	2.72e-200	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HFBHIDMB_00093	2.83e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HFBHIDMB_00094	9.23e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HFBHIDMB_00095	1.69e-151	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HFBHIDMB_00096	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HFBHIDMB_00097	1.88e-35	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HFBHIDMB_00098	1.64e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HFBHIDMB_00099	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HFBHIDMB_00100	1.43e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HFBHIDMB_00101	7.72e-122	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HFBHIDMB_00102	1.43e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HFBHIDMB_00103	3.11e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HFBHIDMB_00104	4.47e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HFBHIDMB_00105	2.89e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HFBHIDMB_00106	9.16e-111	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HFBHIDMB_00107	1.59e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HFBHIDMB_00108	7.32e-95	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
HFBHIDMB_00109	5.7e-298	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HFBHIDMB_00110	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HFBHIDMB_00111	1.59e-243	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HFBHIDMB_00112	1.81e-41	yazB	-	-	K	-	-	-	transcriptional
HFBHIDMB_00113	4.56e-115	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HFBHIDMB_00114	3.8e-80	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HFBHIDMB_00115	1.11e-203	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HFBHIDMB_00116	1.32e-215	pabC	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	4-amino-4-deoxychorismate lyase
HFBHIDMB_00117	4.92e-136	pabA	2.6.1.85	-	EH	ko:K01664	ko00790,map00790	ko00000,ko00001,ko01000	Anthranilate synthase
HFBHIDMB_00118	0.0	pabB	2.6.1.85	-	EH	ko:K01665	ko00790,map00790	ko00000,ko00001,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HFBHIDMB_00119	1.54e-217	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HFBHIDMB_00120	2.07e-205	yacD	5.2.1.8	-	O	ko:K07533	-	ko00000,ko01000,ko03110	peptidyl-prolyl isomerase
HFBHIDMB_00121	9.54e-208	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HFBHIDMB_00122	6.92e-189	coaX	2.7.1.33	-	F	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HFBHIDMB_00123	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HFBHIDMB_00124	4.82e-121	hpt	2.4.2.8, 6.3.4.19	-	F	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Belongs to the purine pyrimidine phosphoribosyltransferase family
HFBHIDMB_00125	0.0	tilS	2.4.2.8, 6.3.4.19	-	D	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HFBHIDMB_00126	2.41e-236	yabT	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HFBHIDMB_00127	3.24e-167	yabS	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
HFBHIDMB_00128	0.0	spoIIE	3.1.3.16	-	KT	ko:K06382	-	ko00000,ko01000	stage II sporulation protein E
HFBHIDMB_00131	2.49e-82	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
HFBHIDMB_00132	4.18e-75	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HFBHIDMB_00133	2.12e-137	yabQ	-	-	S	-	-	-	spore cortex biosynthesis protein
HFBHIDMB_00134	1.91e-66	yabP	-	-	S	-	-	-	Sporulation protein YabP
HFBHIDMB_00135	4.22e-50	yabO	-	-	J	-	-	-	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HFBHIDMB_00136	0.0	yabN	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HFBHIDMB_00137	0.0	yabM	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HFBHIDMB_00138	5.88e-121	spoVT	-	-	K	ko:K04769	-	ko00000,ko03000	stage V sporulation protein
HFBHIDMB_00139	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HFBHIDMB_00140	6.36e-54	yabK	-	-	S	-	-	-	Peptide ABC transporter permease
HFBHIDMB_00141	2.03e-135	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HFBHIDMB_00142	1.45e-136	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HFBHIDMB_00143	1.22e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HFBHIDMB_00144	1e-306	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HFBHIDMB_00145	2.45e-63	spoVG	-	-	D	ko:K06412	-	ko00000	Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HFBHIDMB_00146	3.45e-83	yabJ	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	translation initiation inhibitor, yjgF family
HFBHIDMB_00147	4.66e-196	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HFBHIDMB_00148	2.34e-207	ispE	2.7.1.148	-	I	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HFBHIDMB_00149	3.96e-37	sspF	-	-	S	ko:K06423	-	ko00000	DNA topological change
HFBHIDMB_00150	5.32e-53	veg	-	-	S	-	-	-	protein conserved in bacteria
HFBHIDMB_00151	1.11e-198	yabG	-	-	S	ko:K06436	-	ko00000	peptidase
HFBHIDMB_00152	2.91e-198	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HFBHIDMB_00153	1.43e-125	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HFBHIDMB_00154	1.19e-225	yabE	-	-	T	-	-	-	protein conserved in bacteria
HFBHIDMB_00155	5.9e-184	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD
HFBHIDMB_00156	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HFBHIDMB_00157	9.22e-54	yazA	-	-	L	ko:K07461	-	ko00000	endonuclease containing a URI domain
HFBHIDMB_00158	1.63e-177	yabB	2.1.1.223	-	S	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Conserved hypothetical protein 95
HFBHIDMB_00159	1.53e-56	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HFBHIDMB_00160	6.33e-189	yaaT	-	-	S	-	-	-	stage 0 sporulation protein
HFBHIDMB_00161	8.09e-235	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HFBHIDMB_00162	1.26e-95	yaaR	-	-	S	ko:K09770	-	ko00000	protein conserved in bacteria
HFBHIDMB_00163	1.02e-72	yaaQ	-	-	S	-	-	-	protein conserved in bacteria
HFBHIDMB_00164	1.63e-146	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HFBHIDMB_00165	0.0	yaaO	-	-	E	-	-	-	Orn Lys Arg decarboxylase
HFBHIDMB_00166	8.37e-259	yaaN	-	-	P	-	-	-	Belongs to the TelA family
HFBHIDMB_00167	2.12e-129	xpaC	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
HFBHIDMB_00168	2.21e-42	csfB	-	-	S	-	-	-	Inhibitor of sigma-G Gin
HFBHIDMB_00169	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HFBHIDMB_00170	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HFBHIDMB_00171	1.25e-51	yaaB	-	-	S	-	-	-	Domain of unknown function (DUF370)
HFBHIDMB_00172	1.25e-261	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HFBHIDMB_00173	2.24e-45	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
HFBHIDMB_00174	1.74e-255	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HFBHIDMB_00175	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HFBHIDMB_00176	5.7e-71	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HFBHIDMB_00177	3.78e-178	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HFBHIDMB_00178	1.83e-141	jag	-	-	S	ko:K06346	-	ko00000	single-stranded nucleic acid binding R3H
HFBHIDMB_00179	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HFBHIDMB_00180	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HFBHIDMB_00181	1.01e-167	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HFBHIDMB_00182	9e-193	noc	-	-	D	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HFBHIDMB_00183	4.59e-98	-	-	-	S	-	-	-	Bacterial PH domain
HFBHIDMB_00184	2.77e-172	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	COG1192 ATPases involved in chromosome partitioning
HFBHIDMB_00185	3.96e-191	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HFBHIDMB_00186	4.53e-145	yyaC	-	-	S	-	-	-	Sporulation protein YyaC
HFBHIDMB_00187	2.17e-226	yyaD	-	-	S	-	-	-	Membrane
HFBHIDMB_00188	7.41e-45	yyzM	-	-	S	-	-	-	protein conserved in bacteria
HFBHIDMB_00189	0.0	yyaE	-	-	C	-	-	-	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HFBHIDMB_00190	5.65e-256	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HFBHIDMB_00191	1.01e-61	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HFBHIDMB_00192	1.81e-103	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HFBHIDMB_00193	4.25e-49	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HFBHIDMB_00194	9.06e-182	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HFBHIDMB_00195	4.63e-225	ccpB	-	-	K	-	-	-	Transcriptional regulator
HFBHIDMB_00196	7.2e-90	yyaH	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HFBHIDMB_00197	1.33e-129	vatD	2.3.1.28, 2.3.1.79	-	S	ko:K00638,ko:K00661,ko:K18234	-	br01600,ko00000,ko01000,ko01504	Bacterial transferase hexapeptide (six repeats)
HFBHIDMB_00198	0.0	-	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major facilitator superfamily
HFBHIDMB_00199	6.73e-212	yyaK	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HFBHIDMB_00200	0.0	yyaL	-	-	O	ko:K06888	-	ko00000	COG1331 Highly conserved protein containing a thioredoxin domain
HFBHIDMB_00201	2.7e-205	-	-	-	EG	-	-	-	EamA-like transporter family
HFBHIDMB_00202	1.34e-88	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HFBHIDMB_00203	3.84e-312	tetL	-	-	EGP	ko:K08168	-	ko00000,ko00002,ko01504,ko02000	COG0477 Permeases of the major facilitator superfamily
HFBHIDMB_00204	1.58e-23	yyaL	-	-	O	ko:K06888	-	ko00000	COG1331 Highly conserved protein containing a thioredoxin domain
HFBHIDMB_00205	3.01e-137	yyaP	-	-	H	-	-	-	RibD C-terminal domain
HFBHIDMB_00206	1.82e-86	-	-	-	S	-	-	-	YjbR
HFBHIDMB_00207	1.64e-120	-	-	-	K	ko:K19273	-	ko00000,ko01000,ko01504	Acetyltransferase (GNAT) domain
HFBHIDMB_00208	1.74e-124	yyaS	-	-	S	ko:K07149	-	ko00000	Membrane
HFBHIDMB_00209	2.85e-93	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HFBHIDMB_00210	4.54e-100	yybA	-	-	K	-	-	-	transcriptional
HFBHIDMB_00211	5.29e-165	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HFBHIDMB_00212	2.99e-98	yybC	-	-	-	-	-	-	-
HFBHIDMB_00213	7.91e-104	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HFBHIDMB_00214	2.26e-211	yybE	-	-	K	-	-	-	Transcriptional regulator
HFBHIDMB_00215	1.44e-275	yybF	-	-	EGP	ko:K08224	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HFBHIDMB_00216	7.69e-160	yybG	-	-	S	-	-	-	Pentapeptide repeat-containing protein
HFBHIDMB_00217	1.23e-87	-	-	-	S	-	-	-	SnoaL-like domain
HFBHIDMB_00218	6.85e-182	-	-	-	-	-	-	-	-
HFBHIDMB_00219	8.82e-142	-	-	-	K	-	-	-	TipAS antibiotic-recognition domain
HFBHIDMB_00220	1.01e-307	yybO	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HFBHIDMB_00222	7.84e-91	-	-	-	-	-	-	-	-
HFBHIDMB_00223	4.89e-210	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	Inorganic pyrophosphatase
HFBHIDMB_00224	1.11e-88	yybR	-	-	K	-	-	-	Transcriptional regulator
HFBHIDMB_00225	6.83e-109	cotF	-	-	M	ko:K06329	-	ko00000	Spore coat protein
HFBHIDMB_00227	1.5e-204	yybS	-	-	S	-	-	-	membrane
HFBHIDMB_00228	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HFBHIDMB_00229	2.74e-96	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
HFBHIDMB_00230	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HFBHIDMB_00231	4.19e-283	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	COG2807 Cyanate permease
HFBHIDMB_00232	1.89e-22	yycC	-	-	K	-	-	-	YycC-like protein
HFBHIDMB_00234	3.48e-40	yycD	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
HFBHIDMB_00235	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HFBHIDMB_00236	2.32e-99	yycE	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HFBHIDMB_00237	1.29e-314	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HFBHIDMB_00242	1.45e-172	yycF	-	-	T	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HFBHIDMB_00243	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HFBHIDMB_00244	0.0	yycH	-	-	S	-	-	-	protein conserved in bacteria
HFBHIDMB_00245	6.94e-200	yycI	-	-	S	-	-	-	protein conserved in bacteria
HFBHIDMB_00246	1.15e-190	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
HFBHIDMB_00247	1.56e-277	yyxA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HFBHIDMB_00248	0.0	rocR	-	-	KT	ko:K06714	-	ko00000,ko03000	COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HFBHIDMB_00249	2.31e-54	sdpR	-	-	K	-	-	-	transcriptional
HFBHIDMB_00250	2.54e-85	yvaZ	-	-	S	-	-	-	Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
HFBHIDMB_00251	2.89e-294	rocD	2.6.1.13	-	E	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Catalyzes the interconversion of ornithine to glutamate semialdehyde
HFBHIDMB_00252	0.0	rocE	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HFBHIDMB_00253	3.22e-213	rocF	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
HFBHIDMB_00255	2.38e-236	-	-	-	S	-	-	-	aspartate phosphatase
HFBHIDMB_00256	2.14e-110	yycN	-	-	K	-	-	-	Acetyltransferase
HFBHIDMB_00257	1.13e-167	yycO	-	-	S	-	-	-	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HFBHIDMB_00258	1.64e-265	yycP	-	-	-	-	-	-	-
HFBHIDMB_00259	8.79e-38	yycQ	-	-	S	-	-	-	Protein of unknown function (DUF2651)
HFBHIDMB_00261	1.96e-169	yycR	1.1.1.1, 1.1.1.284, 1.2.1.46	-	E	ko:K00121,ko:K00148	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HFBHIDMB_00262	4.43e-89	yycR	1.1.1.1, 1.1.1.284, 1.2.1.46	-	E	ko:K00121,ko:K00148	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HFBHIDMB_00263	6.92e-82	-	-	-	-	-	-	-	-
HFBHIDMB_00265	7.1e-106	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HFBHIDMB_00266	8.44e-21	spoIVCA	-	-	L	ko:K06400	-	ko00000	Recombinase
HFBHIDMB_00267	1.17e-90	spoIVCA	-	-	L	ko:K06400	-	ko00000	Recombinase
HFBHIDMB_00268	2.23e-11	spoIVCA	-	-	L	ko:K06400	-	ko00000	Recombinase
HFBHIDMB_00269	3.23e-220	-	-	-	V	ko:K07448	-	ko00000,ko02048	Restriction endonuclease
HFBHIDMB_00270	2.9e-64	-	-	-	L	-	-	-	Recombinase zinc beta ribbon domain
HFBHIDMB_00271	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Firmicute fructose-1,6-bisphosphatase
HFBHIDMB_00272	3.42e-142	-	-	-	P	ko:K16917	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HFBHIDMB_00273	1.92e-152	-	-	-	S	ko:K16916	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HFBHIDMB_00274	1.44e-24	-	-	-	-	-	-	-	-
HFBHIDMB_00275	3.34e-24	-	-	-	-	-	-	-	-
HFBHIDMB_00276	6.48e-197	-	-	-	-	-	-	-	-
HFBHIDMB_00277	0.0	ahpF	-	-	O	ko:K03387	-	ko00000,ko01000	Alkyl hydroperoxide reductase
HFBHIDMB_00278	9.33e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Alkyl hydroperoxide reductase
HFBHIDMB_00279	0.0	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HFBHIDMB_00280	2.05e-295	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
HFBHIDMB_00281	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HFBHIDMB_00282	4.42e-164	gntR	-	-	K	ko:K11476	-	ko00000,ko03000	transcriptional
HFBHIDMB_00283	4.71e-263	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HFBHIDMB_00284	9.94e-243	-	-	-	GM	ko:K19426	-	ko00000,ko01000	Polysaccharide pyruvyl transferase
HFBHIDMB_00285	3.63e-152	yxaC	-	-	M	-	-	-	effector of murein hydrolase
HFBHIDMB_00286	5.1e-78	-	-	-	S	ko:K06518	-	ko00000,ko02000	LrgA family
HFBHIDMB_00287	1.13e-92	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HFBHIDMB_00288	2.28e-250	yxnA	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HFBHIDMB_00289	3.91e-130	yxaF	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
HFBHIDMB_00290	6.49e-245	-	1.13.11.24	-	S	ko:K07155	-	ko00000,ko01000	AraC-like ligand binding domain
HFBHIDMB_00291	7.9e-288	-	-	-	P	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
HFBHIDMB_00292	4.03e-99	yxaI	-	-	S	-	-	-	membrane protein domain
HFBHIDMB_00293	4.24e-78	-	-	-	S	-	-	-	Family of unknown function (DUF5391)
HFBHIDMB_00294	1.79e-43	yxaI	-	-	S	-	-	-	membrane protein domain
HFBHIDMB_00295	3.42e-313	aldX	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HFBHIDMB_00296	3.61e-266	yxbF	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HFBHIDMB_00297	1.19e-192	yxbG	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HFBHIDMB_00299	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Molecular chaperone. Has ATPase activity
HFBHIDMB_00300	1.02e-313	csbC	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HFBHIDMB_00301	2.13e-64	yxcD	-	-	S	-	-	-	Protein of unknown function (DUF2653)
HFBHIDMB_00303	7.1e-224	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
HFBHIDMB_00304	1.56e-177	iolR	-	-	K	ko:K06608,ko:K11534	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
HFBHIDMB_00305	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HFBHIDMB_00306	2e-199	iolB	5.3.1.30	-	G	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HFBHIDMB_00307	5e-227	iolC	2.7.1.92	-	G	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HFBHIDMB_00308	0.0	iolD	3.7.1.22	-	E	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HFBHIDMB_00309	2.47e-222	iolE	4.2.1.44	-	G	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HFBHIDMB_00310	4.19e-298	iolF	-	-	EGP	ko:K06610	-	ko00000,ko02000	Major facilitator superfamily
HFBHIDMB_00311	4.44e-251	iolG	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HFBHIDMB_00312	1.08e-212	iolH	-	-	G	ko:K06605	-	ko00000	Xylose isomerase-like TIM barrel
HFBHIDMB_00313	5.39e-187	iolI	5.3.99.11	-	G	ko:K06606	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
HFBHIDMB_00314	2.83e-204	fbaA	4.1.2.13, 4.1.2.29	-	F	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
HFBHIDMB_00315	2.8e-160	yxdJ	-	-	T	ko:K02483,ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HFBHIDMB_00316	9.03e-230	yxdK	2.7.13.3	-	T	ko:K11633	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HFBHIDMB_00317	5.21e-179	yxdL	-	-	V	ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HFBHIDMB_00318	0.0	yxdM	-	-	V	ko:K11636	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
HFBHIDMB_00319	5.95e-77	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HFBHIDMB_00320	7.4e-227	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HFBHIDMB_00321	9.65e-91	-	-	-	-	-	-	-	-
HFBHIDMB_00322	1.76e-26	yxeD	-	-	-	-	-	-	-
HFBHIDMB_00323	7.32e-42	yxeE	-	-	-	-	-	-	-
HFBHIDMB_00326	1.4e-194	yxeH	-	-	S	-	-	-	hydrolases of the HAD superfamily
HFBHIDMB_00327	1.64e-238	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
HFBHIDMB_00328	0.0	yxeK	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HFBHIDMB_00329	2.46e-118	yxeL	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HFBHIDMB_00330	4.3e-186	yxeM	-	-	M	ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HFBHIDMB_00331	5.18e-149	yxeN	-	-	P	ko:K10009,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
HFBHIDMB_00332	1.67e-171	yxeO	-	-	P	ko:K16960,ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HFBHIDMB_00333	1.95e-270	yxeP	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	hydrolase activity
HFBHIDMB_00334	1.21e-315	yxeQ	-	-	S	-	-	-	MmgE/PrpD family
HFBHIDMB_00335	2.21e-255	eutH	-	-	E	ko:K04023	-	ko00000	Ethanolamine utilisation protein, EutH
HFBHIDMB_00336	1.51e-196	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1206)
HFBHIDMB_00337	4.26e-222	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HFBHIDMB_00338	8.3e-150	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HFBHIDMB_00339	2.72e-263	nupC	-	-	F	ko:K11535	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HFBHIDMB_00340	8.11e-299	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	phosphorylase
HFBHIDMB_00341	0.0	ybgF	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HFBHIDMB_00342	8.04e-230	hutG	3.5.3.8	-	E	ko:K01479	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
HFBHIDMB_00343	8.72e-297	hutI	3.5.2.7	-	Q	ko:K01468	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Imidazolone-5-propionate hydrolase
HFBHIDMB_00344	0.0	hutU	4.2.1.49	-	E	ko:K01712	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HFBHIDMB_00345	0.0	hutH	4.3.1.3	-	E	ko:K01745	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Histidine ammonia-lyase
HFBHIDMB_00346	7.02e-103	hutP	-	-	K	ko:K09683	-	ko00000,ko03000	Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
HFBHIDMB_00347	0.0	yxiA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
HFBHIDMB_00348	3.11e-193	-	-	-	L	-	-	-	Protein of unknown function (DUF2726)
HFBHIDMB_00349	1.23e-78	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HFBHIDMB_00350	0.0	-	-	-	L	-	-	-	HKD family nuclease
HFBHIDMB_00351	5.38e-37	-	-	-	S	-	-	-	Domain of unknown function (DUF5082)
HFBHIDMB_00352	3.27e-53	yxiC	-	-	S	-	-	-	Family of unknown function (DUF5344)
HFBHIDMB_00353	1.03e-167	-	-	-	S	ko:K21493	-	ko00000,ko01000,ko02048	nuclease activity
HFBHIDMB_00354	9.21e-44	-	-	-	-	-	-	-	-
HFBHIDMB_00355	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HFBHIDMB_00356	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HFBHIDMB_00357	6.99e-94	yxiE	-	-	T	-	-	-	Belongs to the universal stress protein A family
HFBHIDMB_00358	2.94e-210	yxxF	-	-	EG	-	-	-	EamA-like transporter family
HFBHIDMB_00359	0.0	wapA	-	-	M	-	-	-	COG3209 Rhs family protein
HFBHIDMB_00360	3.29e-19	yxiJ	-	-	S	-	-	-	YxiJ-like protein
HFBHIDMB_00363	8.76e-176	-	-	-	-	-	-	-	-
HFBHIDMB_00364	8.9e-119	-	-	-	S	-	-	-	Protein of unknown function (DUF4240)
HFBHIDMB_00365	3.53e-100	-	-	-	-	-	-	-	-
HFBHIDMB_00366	3.76e-66	-	-	-	-	-	-	-	-
HFBHIDMB_00367	1.9e-88	yxiG	-	-	-	-	-	-	-
HFBHIDMB_00368	3.95e-67	yxxG	-	-	-	-	-	-	-
HFBHIDMB_00369	6.09e-50	-	-	-	S	-	-	-	Protein of unknown function (DUF2750)
HFBHIDMB_00372	2.41e-173	-	-	-	-	-	-	-	-
HFBHIDMB_00373	4.1e-111	yxiI	-	-	S	-	-	-	Protein of unknown function (DUF2716)
HFBHIDMB_00374	7.33e-43	-	-	-	-	-	-	-	-
HFBHIDMB_00377	3.48e-59	yxiJ	-	-	S	-	-	-	YxiJ-like protein
HFBHIDMB_00380	6.52e-270	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HFBHIDMB_00381	0.0	dbpA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
HFBHIDMB_00382	3.8e-292	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	COG2270 Permeases of the major facilitator superfamily
HFBHIDMB_00383	5.32e-143	-	-	-	-	-	-	-	-
HFBHIDMB_00384	5.66e-193	licT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
HFBHIDMB_00385	2.07e-182	bglS	-	-	M	-	-	-	licheninase activity
HFBHIDMB_00386	2e-284	citH	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
HFBHIDMB_00387	0.0	katE	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
HFBHIDMB_00388	6.3e-61	yxiS	-	-	-	-	-	-	-
HFBHIDMB_00389	1.47e-133	-	-	-	T	-	-	-	Domain of unknown function (DUF4163)
HFBHIDMB_00390	2.1e-269	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HFBHIDMB_00391	1.63e-199	yxjB	2.1.1.187	-	Q	ko:K00563	-	ko00000,ko01000,ko03009	Methyltransferase domain
HFBHIDMB_00392	0.0	yxjC	-	-	EG	-	-	-	COG2610 H gluconate symporter and related permeases
HFBHIDMB_00393	4.46e-166	scoA	2.8.3.5	-	I	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HFBHIDMB_00394	5.91e-151	scoB	2.8.3.5	-	I	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HFBHIDMB_00395	2.77e-174	yxjF	1.1.1.30	-	IQ	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HFBHIDMB_00396	1.49e-273	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
HFBHIDMB_00397	2.48e-276	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
HFBHIDMB_00398	4.98e-112	yxjI	-	-	S	-	-	-	LURP-one-related
HFBHIDMB_00400	1.83e-297	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HFBHIDMB_00401	1.1e-147	-	-	-	K	ko:K02479	-	ko00000,ko02022	helix_turn_helix, Lux Regulon
HFBHIDMB_00402	1.04e-244	-	-	-	T	-	-	-	Signal transduction histidine kinase
HFBHIDMB_00403	3.81e-100	-	-	-	S	-	-	-	Protein of unknown function (DUF1453)
HFBHIDMB_00404	1.74e-250	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HFBHIDMB_00405	2.29e-188	yxkD	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HFBHIDMB_00406	8.4e-133	aldY	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HFBHIDMB_00407	1.64e-166	aldY	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HFBHIDMB_00408	1.58e-209	lrp	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
HFBHIDMB_00409	3.44e-261	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HFBHIDMB_00410	5.28e-199	yxkH	-	-	G	-	-	-	Polysaccharide deacetylase
HFBHIDMB_00412	0.0	-	-	-	O	-	-	-	Peptidase family M48
HFBHIDMB_00413	2.67e-308	cimH	-	-	C	-	-	-	COG3493 Na citrate symporter
HFBHIDMB_00414	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
HFBHIDMB_00415	9.56e-243	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase, subunit II
HFBHIDMB_00416	0.0	cydC	-	-	V	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding
HFBHIDMB_00417	0.0	cydD	-	-	V	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding protein
HFBHIDMB_00418	9.16e-203	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HFBHIDMB_00419	0.0	yxlA	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
HFBHIDMB_00420	1.29e-124	sigY	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HFBHIDMB_00421	5.53e-62	yxlC	-	-	S	-	-	-	Family of unknown function (DUF5345)
HFBHIDMB_00422	1.63e-39	-	-	-	-	-	-	-	-
HFBHIDMB_00423	2.17e-39	yxlE	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
HFBHIDMB_00424	8.18e-211	yxlF	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFBHIDMB_00425	9.33e-178	yxlG	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HFBHIDMB_00426	1.95e-271	yxlH	-	-	EGP	-	-	-	Major Facilitator Superfamily
HFBHIDMB_00427	0.0	katX	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
HFBHIDMB_00428	3.23e-145	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HFBHIDMB_00429	8.94e-28	yxzF	-	-	-	-	-	-	-
HFBHIDMB_00430	0.0	licR	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
HFBHIDMB_00431	1.89e-67	licB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	transporter subunit IIB
HFBHIDMB_00432	0.0	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFBHIDMB_00433	1.3e-49	licA	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HFBHIDMB_00434	0.0	licH	3.2.1.86	GT4	G	ko:K01222	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HFBHIDMB_00435	1.77e-262	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HFBHIDMB_00436	2.91e-178	dltE	-	-	M	ko:K14189	-	ko00000,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HFBHIDMB_00437	4.09e-294	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HFBHIDMB_00438	6.83e-50	dltC	6.1.1.13	-	IQ	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HFBHIDMB_00439	1.14e-297	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	membrane protein involved in D-alanine export
HFBHIDMB_00440	0.0	dltA	6.1.1.13	-	Q	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HFBHIDMB_00441	2.08e-212	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
HFBHIDMB_00442	2.52e-149	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	protein conserved in bacteria
HFBHIDMB_00443	0.0	ywaD	3.4.11.10, 3.4.11.6	-	S	ko:K19701	-	ko00000,ko01000,ko01002	PA domain
HFBHIDMB_00444	8.66e-295	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HFBHIDMB_00445	1.25e-114	ywaE	-	-	K	-	-	-	Transcriptional regulator
HFBHIDMB_00446	8.81e-152	ywaF	-	-	S	-	-	-	Integral membrane protein
HFBHIDMB_00447	6.53e-217	gspA	-	-	M	-	-	-	General stress
HFBHIDMB_00448	9.07e-196	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
HFBHIDMB_00449	1.45e-312	sacX	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HFBHIDMB_00450	0.0	epr	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HFBHIDMB_00451	1.17e-307	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFBHIDMB_00452	3.56e-161	ywbB	-	-	S	-	-	-	Protein of unknown function (DUF2711)
HFBHIDMB_00453	4.01e-87	ywbC	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	glyoxalase
HFBHIDMB_00454	1.15e-279	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
HFBHIDMB_00455	6.33e-38	ywbE	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2196)
HFBHIDMB_00456	1.29e-280	ywbF	-	-	EGP	ko:K05820	-	ko00000,ko02000	Nucleoside H+ symporter
HFBHIDMB_00457	1.21e-143	ywbG	-	-	M	-	-	-	effector of murein hydrolase
HFBHIDMB_00458	1.1e-76	ywbH	-	-	S	ko:K06518	-	ko00000,ko02000	Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
HFBHIDMB_00459	2.7e-203	ywbI	-	-	K	-	-	-	Transcriptional regulator
HFBHIDMB_00460	6.56e-185	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HFBHIDMB_00461	2.57e-148	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HFBHIDMB_00462	0.0	-	-	-	P	ko:K07243	-	ko00000,ko02000	COG0672 High-affinity Fe2 Pb2 permease
HFBHIDMB_00463	4.87e-246	ycdO	-	-	P	ko:K07224	-	ko00000,ko02000	periplasmic lipoprotein involved in iron transport
HFBHIDMB_00464	1.04e-306	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Dyp-type peroxidase family protein
HFBHIDMB_00465	1.27e-141	ywbO	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
HFBHIDMB_00466	0.0	ywcA	-	-	S	ko:K14393	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HFBHIDMB_00467	1.23e-63	ywcB	-	-	S	-	-	-	Protein of unknown function, DUF485
HFBHIDMB_00469	2.41e-158	ywcC	-	-	K	-	-	-	transcriptional regulator
HFBHIDMB_00470	3.33e-77	gtcA	-	-	S	-	-	-	GtrA-like protein
HFBHIDMB_00471	5.56e-291	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HFBHIDMB_00472	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HFBHIDMB_00473	5.11e-49	ydaS	-	-	S	-	-	-	membrane
HFBHIDMB_00474	6.94e-226	qoxA	1.10.3.12	-	C	ko:K02826	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HFBHIDMB_00475	0.0	qoxB	1.10.3.12	-	C	ko:K02827	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HFBHIDMB_00476	1.2e-144	qoxC	1.10.3.12	-	C	ko:K02828	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
HFBHIDMB_00477	1.12e-83	qoxD	1.10.3.12	-	C	ko:K02829	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
HFBHIDMB_00478	6.61e-52	ywcE	-	-	S	-	-	-	Required for proper spore morphogenesis. Important for spore germination
HFBHIDMB_00479	8.89e-269	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HFBHIDMB_00480	1.98e-179	nfrA1	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	Oxidoreductase
HFBHIDMB_00481	4.19e-239	ywcH	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HFBHIDMB_00482	0.0	prtS	3.4.21.110, 3.4.21.96	-	O	ko:K01361,ko:K08652,ko:K14647	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HFBHIDMB_00484	1.29e-193	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
HFBHIDMB_00485	2.91e-180	-	-	-	P	ko:K02598	-	ko00000,ko02000	Formate/nitrite transporter
HFBHIDMB_00486	0.0	sacP	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HFBHIDMB_00487	0.0	sacA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HFBHIDMB_00488	6.19e-39	ywdA	-	-	-	-	-	-	-
HFBHIDMB_00489	6.07e-185	pdxK	2.7.1.35, 2.7.1.49, 2.7.4.7	-	H	ko:K00868,ko:K00941	ko00730,ko00750,ko01100,map00730,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HFBHIDMB_00490	3.84e-191	ywdF	-	-	S	-	-	-	Glycosyltransferase like family 2
HFBHIDMB_00491	9.47e-166	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HFBHIDMB_00492	0.0	ywdH	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HFBHIDMB_00493	2.18e-63	ywdI	-	-	S	-	-	-	Family of unknown function (DUF5327)
HFBHIDMB_00494	1.86e-303	ywdJ	-	-	F	-	-	-	Xanthine uracil
HFBHIDMB_00495	1.59e-78	ywdK	-	-	S	-	-	-	small membrane protein
HFBHIDMB_00496	3.62e-112	gerQ	-	-	S	ko:K06305	-	ko00000	Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HFBHIDMB_00497	8.08e-187	spsA	-	-	M	-	-	-	Spore Coat
HFBHIDMB_00498	0.0	spsB	-	-	M	-	-	-	Capsule polysaccharide biosynthesis protein
HFBHIDMB_00499	3.73e-284	spsC	2.6.1.102	-	E	ko:K13010	ko00520,map00520	ko00000,ko00001,ko01000,ko01005,ko01007	Belongs to the DegT DnrJ EryC1 family
HFBHIDMB_00500	4.22e-210	spsD	2.3.1.210	-	K	ko:K16704	-	ko00000,ko01000	Spore Coat
HFBHIDMB_00501	2.27e-270	pseI	2.5.1.56, 2.5.1.97	-	M	ko:K01654,ko:K15898	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	acid synthase
HFBHIDMB_00502	1.23e-164	spsF	-	-	M	ko:K07257	-	ko00000	Spore Coat
HFBHIDMB_00503	5.26e-236	spsG	-	-	M	-	-	-	Spore Coat
HFBHIDMB_00504	6.13e-177	spsI	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HFBHIDMB_00505	9.08e-234	spsJ	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HFBHIDMB_00506	2.44e-206	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HFBHIDMB_00507	9.16e-114	spsL	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Spore Coat
HFBHIDMB_00508	1.51e-100	-	-	-	-	-	-	-	-
HFBHIDMB_00509	6.05e-310	rocG	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HFBHIDMB_00510	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
HFBHIDMB_00511	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
HFBHIDMB_00512	0.0	rocC	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HFBHIDMB_00513	4.44e-274	ywfA	-	-	EGP	-	-	-	-transporter
HFBHIDMB_00514	5.11e-146	bacA	4.1.1.100	-	E	ko:K19546	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
HFBHIDMB_00515	1.24e-175	bacB	5.3.3.19	-	S	ko:K19547	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
HFBHIDMB_00516	3.14e-178	bacC	1.1.1.385	-	IQ	ko:K19548	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HFBHIDMB_00517	0.0	bacD	6.3.2.49	-	F	ko:K13037	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
HFBHIDMB_00518	3.74e-266	bacE	-	-	EGP	ko:K19552	-	ko00000,ko02000	Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
HFBHIDMB_00519	2.21e-297	ywfG	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
HFBHIDMB_00520	2.37e-176	ywfH	-	-	IQ	ko:K19550	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Enoyl-(Acyl carrier protein) reductase
HFBHIDMB_00521	3.43e-187	ywfI	-	-	C	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko01000	May function as heme-dependent peroxidase
HFBHIDMB_00522	1.37e-223	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	In Salmonella this enzyme is required for ethanolamine catabolism
HFBHIDMB_00523	3.73e-209	cysL	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
HFBHIDMB_00524	1.77e-198	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HFBHIDMB_00525	3.8e-196	ywfM	-	-	EG	ko:K03298	-	ko00000,ko02000	EamA-like transporter family
HFBHIDMB_00526	5.39e-145	rsfA_1	-	-	-	ko:K06314	-	ko00000,ko03000	-
HFBHIDMB_00527	8.55e-49	ywzC	-	-	S	-	-	-	Belongs to the UPF0741 family
HFBHIDMB_00528	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	COG1078 HD superfamily phosphohydrolases
HFBHIDMB_00529	1.47e-115	ywgA	-	-	-	ko:K09388	-	ko00000	-
HFBHIDMB_00530	7.42e-102	yffB	-	-	K	-	-	-	Transcriptional regulator
HFBHIDMB_00531	3.73e-301	mmr	-	-	U	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
HFBHIDMB_00533	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HFBHIDMB_00534	1.45e-93	ywhA	-	-	K	-	-	-	Transcriptional regulator
HFBHIDMB_00535	1.43e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	4-oxalocrotonate tautomerase
HFBHIDMB_00536	1.34e-153	ywhC	-	-	S	-	-	-	Peptidase family M50
HFBHIDMB_00537	5.51e-123	ywhD	-	-	S	-	-	-	YwhD family
HFBHIDMB_00538	2.1e-64	-	-	-	-	-	-	-	-
HFBHIDMB_00539	0.0	pbpG	2.4.1.129, 3.4.16.4	GT51	M	ko:K21464	ko00550,map00550	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HFBHIDMB_00540	1.93e-204	speE	2.5.1.16	-	E	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HFBHIDMB_00541	2.1e-215	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
HFBHIDMB_00542	1.09e-32	-	-	-	S	-	-	-	Aminoacyl-tRNA editing domain
HFBHIDMB_00544	9.28e-99	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
HFBHIDMB_00545	3.67e-272	ywhK	-	-	CO	-	-	-	amine dehydrogenase activity
HFBHIDMB_00547	1.09e-313	-	-	-	L	-	-	-	Peptidase, M16
HFBHIDMB_00548	1.7e-276	-	2.7.1.26, 2.7.7.2	-	L	ko:K07263,ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01002	Peptidase, M16
HFBHIDMB_00549	3.42e-297	mgtA	3.6.3.2	-	P	ko:K01531,ko:K16905	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPase, P-type transporting, HAD superfamily, subfamily IC
HFBHIDMB_00550	3.53e-168	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HFBHIDMB_00552	0.0	-	-	-	C	ko:K22227	-	ko00000	Fe-S oxidoreductases
HFBHIDMB_00553	3.71e-12	-	-	-	S	-	-	-	Bacteriocin subtilosin A
HFBHIDMB_00554	4.64e-96	ywiB	-	-	S	-	-	-	protein conserved in bacteria
HFBHIDMB_00555	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HFBHIDMB_00556	1.2e-273	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
HFBHIDMB_00557	3.27e-168	fnr	-	-	K	-	-	-	helix_turn_helix, cAMP Regulatory protein
HFBHIDMB_00558	1.62e-18	ywiC	-	-	S	-	-	-	YwiC-like protein
HFBHIDMB_00559	8.67e-111	arfM	-	-	T	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	cyclic nucleotide binding
HFBHIDMB_00560	0.0	narG	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HFBHIDMB_00561	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase, beta
HFBHIDMB_00562	1.13e-121	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase
HFBHIDMB_00563	1.02e-159	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase (gamma
HFBHIDMB_00564	0.0	ywiE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HFBHIDMB_00565	0.0	ywjA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HFBHIDMB_00566	1.35e-124	ywjB	-	-	H	-	-	-	RibD C-terminal domain
HFBHIDMB_00567	1.32e-57	ywjC	-	-	-	-	-	-	-
HFBHIDMB_00568	5.7e-235	uvsE	-	-	L	ko:K13281	-	ko00000,ko01000	Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
HFBHIDMB_00569	6.46e-285	clsB	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HFBHIDMB_00570	0.0	ywjF	-	-	C	-	-	-	COG0247 Fe-S oxidoreductase
HFBHIDMB_00571	2.98e-269	acdA	-	-	I	-	-	-	acyl-CoA dehydrogenase
HFBHIDMB_00572	1.03e-82	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HFBHIDMB_00573	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HFBHIDMB_00574	3.86e-119	ywjG	-	-	S	-	-	-	Domain of unknown function (DUF2529)
HFBHIDMB_00575	1.07e-81	spo0F	-	-	T	ko:K02490	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG0784 FOG CheY-like receiver
HFBHIDMB_00576	7.82e-204	fbaA	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Aldolase
HFBHIDMB_00577	8.08e-147	tal	2.2.1.2	-	G	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HFBHIDMB_00578	2.26e-303	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HFBHIDMB_00579	2.03e-224	glpX	3.1.3.11	-	G	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	fructose-1,6-bisphosphatase
HFBHIDMB_00580	5.53e-303	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HFBHIDMB_00581	7e-45	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
HFBHIDMB_00582	9.96e-135	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HFBHIDMB_00583	0.0	ykwA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
HFBHIDMB_00584	3.24e-204	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HFBHIDMB_00585	2.93e-108	racA	-	-	K	ko:K11686	-	ko00000,ko03036	Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
HFBHIDMB_00586	1.19e-89	ywkD	-	-	E	ko:K08234	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HFBHIDMB_00587	9.95e-245	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HFBHIDMB_00588	2.42e-204	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HFBHIDMB_00590	5.61e-73	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
HFBHIDMB_00591	1.14e-152	spoIIR	-	-	S	ko:K06387	-	ko00000	stage II sporulation protein R
HFBHIDMB_00592	1.04e-99	ywlB	-	-	E	-	-	-	Belongs to the acetyltransferase family. ArgA subfamily
HFBHIDMB_00593	3e-250	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HFBHIDMB_00594	4.56e-117	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
HFBHIDMB_00595	1.58e-100	ywlE	3.1.3.48, 3.9.1.2	-	T	ko:K01104,ko:K20201	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HFBHIDMB_00596	2.35e-106	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase
HFBHIDMB_00597	2.49e-123	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
HFBHIDMB_00598	5.09e-302	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HFBHIDMB_00599	5.5e-148	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HFBHIDMB_00600	1.91e-81	atpI	-	-	S	ko:K02116	-	ko00000,ko00194	ATP synthase
HFBHIDMB_00601	6.06e-167	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HFBHIDMB_00602	3.01e-36	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HFBHIDMB_00603	2.62e-79	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HFBHIDMB_00604	7.94e-116	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HFBHIDMB_00605	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HFBHIDMB_00606	4.46e-195	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HFBHIDMB_00607	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HFBHIDMB_00608	2.44e-75	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HFBHIDMB_00609	1.76e-114	ywmA	-	-	-	-	-	-	-
HFBHIDMB_00610	4.54e-45	ywzB	-	-	S	-	-	-	membrane
HFBHIDMB_00611	8.01e-173	ywmB	-	-	S	-	-	-	TATA-box binding
HFBHIDMB_00612	4.96e-306	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HFBHIDMB_00613	9.77e-234	spoIID	-	-	D	ko:K06381	-	ko00000	Stage II sporulation protein D
HFBHIDMB_00614	1.89e-157	ywmC	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
HFBHIDMB_00615	1.44e-155	ywmD	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
HFBHIDMB_00617	3.69e-186	fdhD	-	-	C	ko:K02379	-	ko00000	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HFBHIDMB_00618	1.08e-245	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HFBHIDMB_00619	3.1e-129	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
HFBHIDMB_00620	1.72e-109	ywmF	-	-	S	-	-	-	Peptidase M50
HFBHIDMB_00621	1.11e-21	csbD	-	-	K	-	-	-	CsbD-like
HFBHIDMB_00622	5.51e-28	-	-	-	E	ko:K11963	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
HFBHIDMB_00623	8.2e-68	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease gamma subunit family
HFBHIDMB_00624	3.2e-83	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease beta subunit family
HFBHIDMB_00625	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HFBHIDMB_00626	4.58e-85	ywnA	-	-	K	-	-	-	Transcriptional regulator
HFBHIDMB_00627	1.69e-144	ywnB	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HFBHIDMB_00628	1.24e-77	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
HFBHIDMB_00629	4.46e-180	mta	-	-	K	ko:K21743	-	ko00000,ko03000	transcriptional
HFBHIDMB_00630	0.0	ywnE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HFBHIDMB_00631	7.07e-92	ywnF	-	-	S	-	-	-	Family of unknown function (DUF5392)
HFBHIDMB_00632	1.35e-233	-	-	-	M	-	-	-	NeuB family
HFBHIDMB_00633	6.95e-21	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
HFBHIDMB_00634	3.65e-115	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	COG1247 Sortase and related acyltransferases
HFBHIDMB_00635	2.63e-161	spoIIQ	-	-	M	ko:K06386	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
HFBHIDMB_00636	4.49e-93	ywnJ	-	-	S	-	-	-	VanZ like family
HFBHIDMB_00637	6.02e-135	bcrC	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	COG0671 Membrane-associated phospholipid phosphatase
HFBHIDMB_00638	4.51e-77	nrgB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Belongs to the P(II) protein family
HFBHIDMB_00639	6.5e-288	nrgA	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium transporter
HFBHIDMB_00640	2.4e-101	-	-	-	-	-	-	-	-
HFBHIDMB_00641	2.56e-134	yjgF	-	-	Q	-	-	-	Isochorismatase family
HFBHIDMB_00642	8.92e-306	ywoD	-	-	EGP	-	-	-	Major facilitator superfamily
HFBHIDMB_00643	0.0	-	-	-	FH	ko:K03457,ko:K10975	-	ko00000,ko02000	COG1953 Cytosine uracil thiamine allantoin permeases
HFBHIDMB_00644	1.19e-311	ywoF	-	-	P	-	-	-	Right handed beta helix region
HFBHIDMB_00645	5.56e-269	ywoG	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HFBHIDMB_00646	8.45e-92	-	-	-	K	-	-	-	COG1846 Transcriptional regulators
HFBHIDMB_00647	4.88e-59	spoIIID	-	-	K	ko:K06283	-	ko00000,ko03000	Stage III sporulation protein D
HFBHIDMB_00648	1.75e-231	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein
HFBHIDMB_00649	9.79e-170	flhO	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
HFBHIDMB_00650	1.17e-181	flhP	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
HFBHIDMB_00651	1.5e-254	rapD	-	-	S	ko:K06362	-	ko00000,ko01000	aspartate phosphatase
HFBHIDMB_00652	6.89e-107	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HFBHIDMB_00653	1.61e-77	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HFBHIDMB_00654	0.0	ywpD	-	-	T	-	-	-	Histidine kinase
HFBHIDMB_00655	4.13e-222	M1-574	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
HFBHIDMB_00656	0.0	-	-	-	M	-	-	-	cell wall anchor domain
HFBHIDMB_00657	5.03e-108	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HFBHIDMB_00658	2.53e-88	ywpF	-	-	S	-	-	-	YwpF-like protein
HFBHIDMB_00659	5.26e-88	ywpG	-	-	-	-	-	-	-
HFBHIDMB_00660	8.53e-76	ssbB	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
HFBHIDMB_00661	4.82e-180	glcR	-	-	K	ko:K22103	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
HFBHIDMB_00662	5.07e-200	ywpJ	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
HFBHIDMB_00663	0.0	ywqA	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
HFBHIDMB_00664	0.0	ywqB	-	-	S	-	-	-	SWIM zinc finger
HFBHIDMB_00665	3.6e-25	-	-	-	-	-	-	-	-
HFBHIDMB_00666	5.33e-163	ywqC	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
HFBHIDMB_00667	1.06e-152	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
HFBHIDMB_00668	5.87e-179	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	COG4464 Capsular polysaccharide biosynthesis protein
HFBHIDMB_00669	4.66e-313	ywqF	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HFBHIDMB_00670	4.19e-196	ywqG	-	-	S	-	-	-	Domain of unknown function (DUF1963)
HFBHIDMB_00672	2.17e-52	ywqI	-	-	S	-	-	-	Family of unknown function (DUF5344)
HFBHIDMB_00673	2.05e-312	ywqJ	-	-	S	-	-	-	Pre-toxin TG
HFBHIDMB_00674	1.01e-61	-	-	-	-	-	-	-	-
HFBHIDMB_00675	4.61e-66	-	-	-	-	-	-	-	-
HFBHIDMB_00677	4.03e-10	-	-	-	-	-	-	-	-
HFBHIDMB_00678	1.15e-67	-	-	-	-	-	-	-	-
HFBHIDMB_00679	4.92e-154	nfi	3.1.21.7	-	L	ko:K05982	-	ko00000,ko01000,ko03400	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
HFBHIDMB_00680	2.34e-209	-	-	-	K	-	-	-	Transcriptional regulator
HFBHIDMB_00681	3.68e-130	ywqN	-	-	S	-	-	-	NAD(P)H-dependent
HFBHIDMB_00683	6.07e-114	ywrA	-	-	P	ko:K07240	-	ko00000,ko02000	COG2059 Chromate transport protein ChrA
HFBHIDMB_00684	6.44e-132	ywrB	-	-	P	ko:K07240	-	ko00000,ko02000	Chromate transporter
HFBHIDMB_00685	2.79e-107	ywrC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
HFBHIDMB_00686	0.0	ywrD	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
HFBHIDMB_00687	2.78e-71	-	-	-	S	-	-	-	Domain of unknown function (DUF4181)
HFBHIDMB_00688	1.77e-142	ywrF	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HFBHIDMB_00689	2.99e-16	-	-	-	-	-	-	-	-
HFBHIDMB_00690	2.64e-268	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
HFBHIDMB_00691	1.37e-194	cotB	-	-	-	ko:K06325	-	ko00000	-
HFBHIDMB_00692	2.5e-161	ywrJ	-	-	-	-	-	-	-
HFBHIDMB_00693	4.82e-281	ywrK	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HFBHIDMB_00694	9.64e-218	alsR	-	-	K	-	-	-	LysR substrate binding domain
HFBHIDMB_00695	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HFBHIDMB_00696	1.84e-187	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
HFBHIDMB_00697	2.15e-126	ywrO	-	-	S	-	-	-	NADPH-quinone reductase (modulator of drug activity B)
HFBHIDMB_00698	1.53e-62	ywsA	-	-	S	-	-	-	Protein of unknown function (DUF3892)
HFBHIDMB_00699	4.83e-120	batE	-	-	T	-	-	-	Sh3 type 3 domain protein
HFBHIDMB_00700	2.59e-203	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	COG1879 ABC-type sugar transport system, periplasmic component
HFBHIDMB_00701	3.35e-203	rbsC	-	-	G	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HFBHIDMB_00702	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HFBHIDMB_00703	6.55e-84	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HFBHIDMB_00704	6.18e-205	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HFBHIDMB_00705	2.68e-227	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
HFBHIDMB_00706	1.46e-283	capB	-	-	M	ko:K01932	-	ko00000,ko01000	COG0769 UDP-N-acetylmuramyl tripeptide synthase
HFBHIDMB_00707	8.44e-91	capC	-	-	S	ko:K22116	-	ko00000	biosynthesis protein
HFBHIDMB_00708	1.1e-276	capA	-	-	M	ko:K07282	-	ko00000	enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
HFBHIDMB_00709	2.29e-29	ywtC	-	-	-	-	-	-	-
HFBHIDMB_00710	5.14e-304	pgdS	-	-	M	-	-	-	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HFBHIDMB_00711	3.3e-201	ywtE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
HFBHIDMB_00712	1.67e-176	ywtF_2	-	-	K	-	-	-	Transcriptional regulator
HFBHIDMB_00713	1.06e-313	ywtG	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HFBHIDMB_00714	1.03e-262	gerBC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination protein
HFBHIDMB_00715	1.48e-248	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
HFBHIDMB_00716	0.0	gerBA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
HFBHIDMB_00717	4.34e-237	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HFBHIDMB_00718	0.0	lytD	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HFBHIDMB_00719	1.5e-257	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HFBHIDMB_00720	5.03e-183	tagA	2.4.1.187	GT26	M	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HFBHIDMB_00721	2.4e-90	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Cytidylyltransferase
HFBHIDMB_00722	0.0	tagF	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HFBHIDMB_00723	0.0	tagF2	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HFBHIDMB_00726	3.02e-171	tagG	-	-	GM	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
HFBHIDMB_00727	2.7e-204	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HFBHIDMB_00728	1.74e-13	-	-	-	L	-	-	-	COG2963 Transposase and inactivated derivatives
HFBHIDMB_00729	1.64e-204	gtaB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HFBHIDMB_00730	2.43e-264	mnaA	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HFBHIDMB_00731	4.48e-22	lytR	-	-	K	-	-	-	May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HFBHIDMB_00732	2.52e-40	lytR	-	-	K	-	-	-	May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HFBHIDMB_00733	1.39e-15	-	-	-	-	-	-	-	-
HFBHIDMB_00734	0.0	lytB	-	-	D	-	-	-	Stage II sporulation protein
HFBHIDMB_00735	0.0	lytC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
HFBHIDMB_00736	2.13e-150	tuaA	-	-	M	-	-	-	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HFBHIDMB_00737	1.28e-300	tuaB	-	-	S	ko:K03328,ko:K16694,ko:K16695	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HFBHIDMB_00738	4.27e-257	tuaC	-	GT4	GM	ko:K16697	-	ko00000,ko01000,ko01003	Teichuronic acid
HFBHIDMB_00739	2.01e-302	tuaD	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HFBHIDMB_00740	9.1e-315	tuaE	-	-	M	ko:K16705	-	ko00000	Teichuronic acid biosynthesis protein
HFBHIDMB_00741	9.78e-136	tuaF	-	-	M	ko:K16706	-	ko00000	protein involved in exopolysaccharide biosynthesis
HFBHIDMB_00742	1.61e-175	tuaG	-	GT2	M	ko:K16698	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
HFBHIDMB_00743	7.67e-293	tuaH	-	-	M	ko:K16699	-	ko00000,ko01000,ko01003	Teichuronic acid biosynthesis glycosyltransferase tuaH
HFBHIDMB_00744	2.1e-231	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
HFBHIDMB_00746	6.05e-100	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFBHIDMB_00749	2.9e-50	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HFBHIDMB_00752	1.23e-151	-	-	-	K	-	-	-	Transcriptional regulator
HFBHIDMB_00753	1.94e-136	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	Domain of unknown function (DUF1949)
HFBHIDMB_00754	2.94e-247	degS	2.7.13.3	-	T	ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HFBHIDMB_00755	7.16e-163	degU	-	-	KT	ko:K02479,ko:K07692	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HFBHIDMB_00756	2.51e-198	degV	-	-	S	-	-	-	protein conserved in bacteria
HFBHIDMB_00757	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HFBHIDMB_00758	1.26e-61	comFB	-	-	S	ko:K02241	-	ko00000,ko00002,ko02044	Late competence development protein ComFB
HFBHIDMB_00759	2.26e-162	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Phosphoribosyl transferase domain
HFBHIDMB_00760	1.06e-95	yvyF	-	-	S	-	-	-	flagellar protein
HFBHIDMB_00761	8.72e-53	flgM	-	-	KNU	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	ko00000,ko00001,ko02035	Negative regulator of flagellin synthesis
HFBHIDMB_00762	7.06e-102	yvyG	-	-	NOU	-	-	-	FlgN protein
HFBHIDMB_00763	0.0	flgK	-	-	N	ko:K02396	ko02040,map02040	ko00000,ko00001,ko02035	flagellar hook-associated protein
HFBHIDMB_00764	7.66e-197	flgL	-	-	N	ko:K02397	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the bacterial flagellin family
HFBHIDMB_00765	6.92e-92	yviE	-	-	-	-	-	-	-
HFBHIDMB_00766	1.23e-96	fliW	-	-	S	ko:K13626	-	ko00000,ko02035	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HFBHIDMB_00767	1.05e-40	csrA	-	-	T	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	ko00000,ko00001,ko03019	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HFBHIDMB_00768	2.16e-157	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HFBHIDMB_00769	3.03e-74	flaG	-	-	N	ko:K06603	-	ko00000,ko02035	flagellar protein FlaG
HFBHIDMB_00770	0.0	fliD	-	-	N	ko:K02407	ko02040,map02040	ko00000,ko00001,ko02035	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HFBHIDMB_00771	1.48e-90	fliS	-	-	N	ko:K02422	ko02040,map02040	ko00000,ko00001,ko02035	flagellar protein FliS
HFBHIDMB_00772	8.69e-09	fliT	-	-	S	ko:K02423	ko02040,map02040	ko00000,ko00001,ko02035	bacterial-type flagellum organization
HFBHIDMB_00773	2.46e-67	-	-	-	-	-	-	-	-
HFBHIDMB_00774	1.73e-132	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HFBHIDMB_00775	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HFBHIDMB_00776	2.33e-231	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HFBHIDMB_00777	7.58e-184	yvjA	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HFBHIDMB_00778	5.37e-74	cccB	-	-	C	ko:K12263,ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
HFBHIDMB_00779	3.03e-159	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
HFBHIDMB_00780	1.56e-198	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HFBHIDMB_00781	0.0	ctpB	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HFBHIDMB_00782	1.38e-73	swrA	-	-	S	-	-	-	Swarming motility protein
HFBHIDMB_00783	1.83e-279	minJ	-	-	O	-	-	-	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HFBHIDMB_00784	7.12e-294	yvkA	-	-	P	-	-	-	-transporter
HFBHIDMB_00785	1.43e-131	yvkB	-	-	K	-	-	-	Transcriptional regulator
HFBHIDMB_00786	0.0	yvkC	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Phosphotransferase
HFBHIDMB_00787	2.54e-42	csbA	-	-	S	-	-	-	protein conserved in bacteria
HFBHIDMB_00788	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HFBHIDMB_00789	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HFBHIDMB_00790	1.68e-157	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HFBHIDMB_00791	2.25e-45	yvkN	-	-	-	-	-	-	-
HFBHIDMB_00792	8.09e-65	yvlA	-	-	-	-	-	-	-
HFBHIDMB_00793	5.54e-219	yvlB	-	-	S	-	-	-	Putative adhesin
HFBHIDMB_00794	1.5e-36	yvlC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
HFBHIDMB_00795	3.8e-66	yvlD	-	-	S	ko:K08972	-	ko00000	Membrane
HFBHIDMB_00796	4.26e-272	yvmA	-	-	EGP	-	-	-	Major Facilitator Superfamily
HFBHIDMB_00797	1.03e-112	yvmB	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HFBHIDMB_00798	7.15e-177	yvmC	2.3.2.22	-	S	ko:K17485	-	ko00000,ko01000	Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
HFBHIDMB_00799	9.32e-293	cypX	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
HFBHIDMB_00800	4.13e-104	yvnA	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HFBHIDMB_00801	0.0	yvnB	-	-	Q	-	-	-	Calcineurin-like phosphoesterase
HFBHIDMB_00802	3.02e-171	yvoA	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
HFBHIDMB_00803	1.95e-162	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HFBHIDMB_00804	9.81e-279	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HFBHIDMB_00805	3.62e-217	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HFBHIDMB_00806	2.61e-194	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HFBHIDMB_00807	2.06e-208	yvoD	-	-	P	-	-	-	COG0370 Fe2 transport system protein B
HFBHIDMB_00808	3.05e-153	ppaX	3.6.1.1	-	S	ko:K06019	ko00190,map00190	ko00000,ko00001,ko01000	Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HFBHIDMB_00809	5.94e-118	yvoF	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
HFBHIDMB_00810	1.05e-151	-	4.2.2.10, 4.2.2.2	-	G	ko:K19551	ko00040,map00040	ko00000,ko00001,ko01000	Pectate lyase
HFBHIDMB_00811	2.14e-179	yvpB	-	-	NU	-	-	-	protein conserved in bacteria
HFBHIDMB_00812	9.84e-281	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HFBHIDMB_00813	1.06e-147	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HFBHIDMB_00814	7.38e-292	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HFBHIDMB_00815	4.96e-139	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
HFBHIDMB_00816	8.08e-147	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HFBHIDMB_00817	7.64e-166	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HFBHIDMB_00818	2.29e-175	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HFBHIDMB_00819	6.37e-142	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the PRA-CH family
HFBHIDMB_00820	7.95e-116	-	-	-	S	-	-	-	Predicted membrane protein (DUF2339)
HFBHIDMB_00821	1.34e-75	-	-	-	-	-	-	-	-
HFBHIDMB_00822	2e-72	-	-	-	-	-	-	-	-
HFBHIDMB_00823	1.06e-110	-	-	-	-	-	-	-	-
HFBHIDMB_00824	2.8e-27	-	-	-	-	-	-	-	-
HFBHIDMB_00825	0.0	-	-	-	-	-	-	-	-
HFBHIDMB_00827	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HFBHIDMB_00828	0.0	yvcD	-	-	S	-	-	-	COG0457 FOG TPR repeat
HFBHIDMB_00829	2.18e-184	spl	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	protein conserved in bacteria
HFBHIDMB_00830	1.18e-225	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HFBHIDMB_00831	2.39e-117	yvcI	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HFBHIDMB_00832	8.53e-213	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HFBHIDMB_00833	3.19e-225	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HFBHIDMB_00834	1.04e-219	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HFBHIDMB_00835	3.92e-50	crh	-	-	G	ko:K11184	-	ko00000	Phosphocarrier protein Chr
HFBHIDMB_00836	4.64e-182	yvcN	2.3.1.118	-	Q	ko:K00675	-	ko00000,ko01000	Belongs to the arylamine N-acetyltransferase family
HFBHIDMB_00837	7.95e-45	-	-	-	-	-	-	-	-
HFBHIDMB_00838	3.84e-171	yvcP	-	-	T	ko:K02483,ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HFBHIDMB_00839	9.29e-250	yvcQ	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HFBHIDMB_00840	4.46e-181	yxdL_2	-	-	V	ko:K02003,ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HFBHIDMB_00841	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
HFBHIDMB_00842	2.7e-233	yvcT	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFBHIDMB_00843	8.79e-136	yvdA	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
HFBHIDMB_00844	0.0	yvdB	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
HFBHIDMB_00845	7.84e-71	yvdC	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
HFBHIDMB_00846	6.28e-136	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HFBHIDMB_00847	1.54e-221	yvdE	-	-	K	-	-	-	Transcriptional regulator
HFBHIDMB_00848	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, N-terminal ig-like domain
HFBHIDMB_00849	4.02e-300	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
HFBHIDMB_00850	3.37e-308	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
HFBHIDMB_00851	6.84e-190	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
HFBHIDMB_00852	5.26e-202	malA	-	-	S	-	-	-	Protein of unknown function (DUF1189)
HFBHIDMB_00853	0.0	yvdK	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycoside hydrolase, family 65
HFBHIDMB_00854	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
HFBHIDMB_00855	3.35e-115	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HFBHIDMB_00856	8.17e-135	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HFBHIDMB_00858	8.57e-40	-	-	-	L	-	-	-	Phage integrase family
HFBHIDMB_00859	5.97e-147	-	-	-	S	-	-	-	Helix-turn-helix domain
HFBHIDMB_00860	8.52e-129	-	-	-	L	-	-	-	Phage integrase family
HFBHIDMB_00861	4.52e-42	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HFBHIDMB_00862	9.08e-38	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HFBHIDMB_00863	3.13e-62	-	-	-	-	-	-	-	-
HFBHIDMB_00864	1.02e-307	-	-	-	I	-	-	-	Pfam Lipase (class 3)
HFBHIDMB_00867	5.74e-20	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HFBHIDMB_00868	9.31e-36	-	-	-	-	-	-	-	-
HFBHIDMB_00873	4.1e-111	-	-	-	-	-	-	-	-
HFBHIDMB_00874	5.18e-165	-	-	-	-	-	-	-	-
HFBHIDMB_00875	6.22e-43	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HFBHIDMB_00883	0.0	-	-	-	D	-	-	-	Phage tail tape measure protein
HFBHIDMB_00885	3.55e-15	-	-	-	K	-	-	-	acetyltransferase
HFBHIDMB_00886	5.53e-122	yvdQ	-	-	S	-	-	-	Protein of unknown function (DUF3231)
HFBHIDMB_00887	1.03e-66	yvdR	-	-	P	ko:K11741	-	ko00000,ko02000	Small Multidrug Resistance protein
HFBHIDMB_00888	6.31e-68	yvdS	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
HFBHIDMB_00889	1.17e-137	yvdT_1	-	-	K	-	-	-	Transcriptional regulator
HFBHIDMB_00890	0.0	ybeC	-	-	E	-	-	-	amino acid
HFBHIDMB_00891	0.0	sacC3	3.2.1.65	GH32	G	ko:K01212	ko00500,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
HFBHIDMB_00892	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	levansucrase activity
HFBHIDMB_00893	7.19e-86	-	-	-	-	-	-	-	-
HFBHIDMB_00894	0.0	pbpE	-	-	V	-	-	-	Beta-lactamase
HFBHIDMB_00895	2.06e-161	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HFBHIDMB_00896	1.75e-93	-	-	-	S	-	-	-	Protein of unknown function (DUF3237)
HFBHIDMB_00897	5.4e-120	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
HFBHIDMB_00899	0.0	pnbA	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
HFBHIDMB_00900	1.24e-98	-	-	-	K	ko:K19417	-	ko00000,ko03000	transcriptional
HFBHIDMB_00901	1.61e-157	epsA	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
HFBHIDMB_00902	7.94e-150	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
HFBHIDMB_00903	0.0	capD	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
HFBHIDMB_00904	3.04e-279	epsD	-	GT4	M	ko:K19422	-	ko00000,ko01000	Glycosyl transferase 4-like
HFBHIDMB_00905	1.25e-201	epsE	-	GT2	M	ko:K19423	-	ko00000,ko01000,ko01003	COG0463 Glycosyltransferases involved in cell wall biogenesis
HFBHIDMB_00906	4.67e-280	epsF	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HFBHIDMB_00907	8.82e-265	epsG	-	-	S	ko:K19419	-	ko00000,ko02000	EpsG family
HFBHIDMB_00908	6.04e-249	epsH	-	GT2	S	ko:K19425	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
HFBHIDMB_00909	7.76e-259	epsI	-	-	GM	ko:K19426	-	ko00000,ko01000	pyruvyl transferase
HFBHIDMB_00910	6.76e-246	epsJ	-	GT2	S	ko:K19427	-	ko00000,ko01000	COG0463 Glycosyltransferases involved in cell wall biogenesis
HFBHIDMB_00911	0.0	epsK	-	-	S	ko:K19418	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HFBHIDMB_00912	9.14e-139	epsL	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HFBHIDMB_00913	1.22e-82	epsM	-	-	GM	ko:K19429	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
HFBHIDMB_00914	1.76e-277	epsN	-	-	E	ko:K19430	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
HFBHIDMB_00915	1.1e-233	epsO	-	-	GM	ko:K19431	-	ko00000,ko01000	Exopolysaccharide biosynthesis protein
HFBHIDMB_00916	5.69e-44	yvfG	-	-	S	-	-	-	YvfG protein
HFBHIDMB_00917	1.36e-303	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
HFBHIDMB_00918	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HFBHIDMB_00919	2.79e-145	yvfI	-	-	K	ko:K05799	-	ko00000,ko03000	COG2186 Transcriptional regulators
HFBHIDMB_00920	2.33e-235	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HFBHIDMB_00921	4.62e-292	cycB	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
HFBHIDMB_00922	5.29e-301	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
HFBHIDMB_00923	3.82e-194	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
HFBHIDMB_00924	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	beta-galactosidase
HFBHIDMB_00925	0.0	ganB	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
HFBHIDMB_00926	2.51e-264	-	3.1.3.3	-	T	ko:K07315	-	ko00000,ko01000,ko03021	response regulator
HFBHIDMB_00927	2.08e-200	rsbQ	-	-	S	ko:K19707	-	ko00000,ko03021	Alpha/beta hydrolase family
HFBHIDMB_00929	1.5e-202	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
HFBHIDMB_00930	2.04e-170	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
HFBHIDMB_00931	1.8e-250	yvfT	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HFBHIDMB_00932	4.36e-136	desR	-	-	T	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HFBHIDMB_00933	9.08e-175	lutA	-	-	C	ko:K18928	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HFBHIDMB_00934	0.0	lutB	-	-	C	ko:K18929	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
HFBHIDMB_00935	8.37e-172	lutC	-	-	S	ko:K00782	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HFBHIDMB_00936	7.05e-248	-	-	-	S	-	-	-	Glycosyl hydrolase
HFBHIDMB_00937	4.09e-306	yvbW	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
HFBHIDMB_00938	1.6e-197	yvbV	-	-	EG	-	-	-	EamA-like transporter family
HFBHIDMB_00939	4.02e-205	yvbU	-	-	K	-	-	-	Transcriptional regulator
HFBHIDMB_00940	1.04e-245	yvbT	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HFBHIDMB_00941	8.72e-258	araR	-	-	K	ko:K02103	-	ko00000,ko03000	transcriptional
HFBHIDMB_00942	0.0	araE	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HFBHIDMB_00943	2.7e-234	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HFBHIDMB_00944	5.72e-238	gapA	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HFBHIDMB_00945	1.97e-277	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HFBHIDMB_00946	2.12e-176	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HFBHIDMB_00947	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and
HFBHIDMB_00948	1.38e-309	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HFBHIDMB_00949	9.77e-106	yvbK	-	-	K	-	-	-	acetyltransferase
HFBHIDMB_00950	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
HFBHIDMB_00951	3.95e-157	yvbI	-	-	M	-	-	-	Membrane
HFBHIDMB_00952	1.03e-145	yvbH	-	-	S	-	-	-	YvbH-like oligomerisation region
HFBHIDMB_00953	9.68e-136	yvbG	-	-	U	ko:K05595	-	ko00000,ko02000	UPF0056 membrane protein
HFBHIDMB_00954	8.29e-129	yvbF	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
HFBHIDMB_00955	5.58e-270	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HFBHIDMB_00956	5.63e-145	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
HFBHIDMB_00957	7.4e-223	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HFBHIDMB_00958	5.59e-136	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
HFBHIDMB_00959	6.63e-122	yvbF	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
HFBHIDMB_00960	2.02e-268	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HFBHIDMB_00961	1.55e-142	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
HFBHIDMB_00962	3.77e-217	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HFBHIDMB_00963	2.48e-134	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
HFBHIDMB_00964	1.04e-231	bsaB	-	-	S	ko:K20483	ko02020,ko02024,map02020,map02024	ko00000,ko00001	Lantibiotic dehydratase, C terminus
HFBHIDMB_00965	8.57e-193	-	-	-	V	ko:K06147,ko:K06148,ko:K20485	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	ABC transporter
HFBHIDMB_00966	1.18e-97	spaC1	-	-	V	ko:K20484	ko02020,ko02024,map02020,map02024	ko00000,ko00001	Lanthionine synthetase C-like protein
HFBHIDMB_00969	7.1e-131	spaF	-	-	V	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HFBHIDMB_00970	1.67e-110	spaE	-	-	S	ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HFBHIDMB_00971	1.49e-103	spaG	-	-	S	ko:K20492	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HFBHIDMB_00972	1.41e-135	spaR	-	-	K	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
HFBHIDMB_00973	2.54e-195	spaK	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
HFBHIDMB_00974	0.0	yvaQ	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HFBHIDMB_00975	3.85e-72	yvaP	-	-	K	-	-	-	transcriptional
HFBHIDMB_00976	9.82e-92	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
HFBHIDMB_00977	4.08e-92	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	transcriptional
HFBHIDMB_00978	3.44e-48	yvzC	-	-	K	-	-	-	transcriptional
HFBHIDMB_00979	5.51e-192	yvaM	1.11.1.10	-	S	ko:K00433	-	ko00000,ko01000	Serine aminopeptidase, S33
HFBHIDMB_00980	1.87e-35	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit SecG
HFBHIDMB_00981	3.43e-183	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Carboxylesterase
HFBHIDMB_00982	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HFBHIDMB_00983	2.4e-107	smpB	-	-	O	ko:K03664	-	ko00000	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HFBHIDMB_00985	3.96e-182	yvaG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
HFBHIDMB_00986	4.23e-129	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HFBHIDMB_00987	5.85e-70	yvaE	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
HFBHIDMB_00988	8.22e-97	yvaD	-	-	S	-	-	-	Family of unknown function (DUF5360)
HFBHIDMB_00989	0.0	-	-	-	S	-	-	-	Fusaric acid resistance protein-like
HFBHIDMB_00990	2.08e-153	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HFBHIDMB_00991	5.71e-247	yvaA	1.1.1.371	-	S	ko:K16044	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
HFBHIDMB_00992	4.67e-63	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	transcriptional
HFBHIDMB_00993	3.02e-40	copZ	-	-	P	ko:K07213	ko04978,map04978	ko00000,ko00001	Copper resistance protein CopZ
HFBHIDMB_00994	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HFBHIDMB_00995	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
HFBHIDMB_00996	3.45e-137	bdbD	-	-	O	-	-	-	Thioredoxin
HFBHIDMB_00997	5.7e-95	bdbC	-	-	O	ko:K03611	-	ko00000,ko03110	Required for disulfide bond formation in some proteins
HFBHIDMB_00998	2.34e-139	yvgT	-	-	S	-	-	-	membrane
HFBHIDMB_01000	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HFBHIDMB_01001	0.0	cysJ	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HFBHIDMB_01002	0.0	cysI	1.8.1.2, 1.8.7.1	-	P	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HFBHIDMB_01003	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	COG0025 NhaP-type Na H and K H antiporters
HFBHIDMB_01004	9.32e-112	yvgO	-	-	-	-	-	-	-
HFBHIDMB_01005	1.77e-200	yvgN	-	-	S	-	-	-	reductase
HFBHIDMB_01006	3.52e-153	modB	-	-	P	ko:K02018	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4149 ABC-type molybdate transport system, permease component
HFBHIDMB_01007	8.23e-175	modA	-	-	P	ko:K02020	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0725 ABC-type molybdate transport system, periplasmic component
HFBHIDMB_01008	2.44e-212	yvgK	-	-	P	ko:K07219	-	ko00000	COG1910 Periplasmic molybdate-binding protein domain
HFBHIDMB_01009	0.0	yvgJ	-	-	M	ko:K01138	-	ko00000,ko01000	Belongs to the LTA synthase family
HFBHIDMB_01010	3.95e-108	yvsG	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
HFBHIDMB_01011	9.37e-23	-	-	-	S	ko:K06427	-	ko00000	Small spore protein J (Spore_SspJ)
HFBHIDMB_01012	0.0	yvsH	-	-	E	ko:K03294,ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
HFBHIDMB_01014	3.13e-225	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HFBHIDMB_01015	1.72e-236	fhuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HFBHIDMB_01016	3.22e-224	fhuG	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HFBHIDMB_01017	2.92e-191	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HFBHIDMB_01018	3.61e-231	-	-	-	M	ko:K02005	-	ko00000	Efflux transporter rnd family, mfp subunit
HFBHIDMB_01019	1.09e-157	yvrO	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFBHIDMB_01020	7.7e-273	yvrN	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
HFBHIDMB_01021	9.89e-86	yvrL	-	-	S	-	-	-	Regulatory protein YrvL
HFBHIDMB_01022	2.17e-290	oxdC	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
HFBHIDMB_01023	3.46e-26	-	-	-	S	-	-	-	YvrJ protein family
HFBHIDMB_01024	4.06e-127	yvrI	-	-	K	ko:K03093	-	ko00000,ko03021	RNA polymerase
HFBHIDMB_01025	6.16e-33	-	-	-	-	-	-	-	-
HFBHIDMB_01026	1.1e-170	yvrH	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HFBHIDMB_01027	0.0	yvrG	-	-	T	-	-	-	Histidine kinase
HFBHIDMB_01028	1.32e-219	yvrE	-	-	G	ko:K14274	ko00040,map00040	ko00000,ko00001,ko01000	SMP-30/Gluconolaconase/LRE-like region
HFBHIDMB_01029	2.12e-181	yvrD	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HFBHIDMB_01030	1.36e-214	btuF	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
HFBHIDMB_01031	7.4e-234	btuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HFBHIDMB_01032	2.12e-308	yvrA	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HFBHIDMB_01033	1.93e-131	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Adenosyltransferase
HFBHIDMB_01034	6.23e-286	yvqJ	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HFBHIDMB_01035	4.68e-79	liaI	-	-	S	ko:K11619	ko02020,map02020	ko00000,ko00001,ko00002	membrane
HFBHIDMB_01036	9.94e-143	liaH	-	-	KT	ko:K03969,ko:K11620	ko02020,map02020	ko00000,ko00001,ko00002	COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
HFBHIDMB_01037	5.74e-172	liaG	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
HFBHIDMB_01038	2.1e-161	-	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
HFBHIDMB_01039	2.25e-243	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HFBHIDMB_01040	6.34e-139	vraR	-	-	KT	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HFBHIDMB_01041	1.76e-242	gerAC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination B3/ GerAC like, C-terminal
HFBHIDMB_01042	9.28e-250	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
HFBHIDMB_01043	0.0	gerAA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
HFBHIDMB_01044	2.6e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF3970)
HFBHIDMB_01045	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HFBHIDMB_01046	3.06e-204	yuxN	-	-	K	-	-	-	Transcriptional regulator
HFBHIDMB_01047	2.77e-316	cssS	2.7.13.3	-	T	ko:K07650	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HFBHIDMB_01048	2.23e-164	cssR	-	-	T	ko:K07770	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HFBHIDMB_01049	1.12e-304	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HFBHIDMB_01050	2.15e-104	fri	-	-	P	ko:K04047	-	ko00000,ko03036	Ferritin-like domain
HFBHIDMB_01051	7.45e-195	yusZ	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HFBHIDMB_01052	0.0	pepF2	-	-	E	-	-	-	COG1164 Oligoendopeptidase F
HFBHIDMB_01053	3.48e-88	-	-	-	S	-	-	-	YusW-like protein
HFBHIDMB_01054	2.51e-195	yusV	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HFBHIDMB_01055	3.01e-63	yusU	-	-	S	-	-	-	Protein of unknown function (DUF2573)
HFBHIDMB_01056	8.42e-204	gltR	-	-	K	ko:K21959	-	ko00000,ko03000	LysR substrate binding domain
HFBHIDMB_01057	4.97e-138	yusR	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
HFBHIDMB_01058	1.7e-84	yusQ	-	-	S	-	-	-	Tautomerase enzyme
HFBHIDMB_01059	0.0	yusP	-	-	P	-	-	-	Major facilitator superfamily
HFBHIDMB_01060	6.35e-98	yusO	-	-	K	-	-	-	Iron dependent repressor, N-terminal DNA binding domain
HFBHIDMB_01061	8.66e-70	yusN	-	-	M	-	-	-	Coat F domain
HFBHIDMB_01062	4.51e-54	-	-	-	-	-	-	-	-
HFBHIDMB_01063	6.98e-211	fadM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
HFBHIDMB_01064	1.11e-13	-	-	-	S	-	-	-	YuzL-like protein
HFBHIDMB_01065	0.0	fadN	1.1.1.35	-	I	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	ko00000,ko00001,ko00002,ko01000	3-hydroxyacyl-CoA dehydrogenase
HFBHIDMB_01066	1.34e-278	fadA	2.3.1.16	-	I	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the thiolase family
HFBHIDMB_01067	0.0	fadE	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
HFBHIDMB_01068	1.01e-83	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
HFBHIDMB_01069	5.91e-85	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
HFBHIDMB_01070	7.34e-54	yusG	-	-	S	-	-	-	Protein of unknown function (DUF2553)
HFBHIDMB_01071	7.62e-97	yusF	-	-	L	ko:K07476	-	ko00000	COG1658 Small primase-like proteins (Toprim domain)
HFBHIDMB_01072	8.14e-73	yusE	-	-	CO	-	-	-	Thioredoxin
HFBHIDMB_01073	1.53e-74	yusD	-	-	S	-	-	-	SCP-2 sterol transfer family
HFBHIDMB_01074	3.05e-236	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HFBHIDMB_01075	6.5e-126	metI	-	-	P	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2011 ABC-type metal ion transport system, permease component
HFBHIDMB_01076	8.33e-189	metQ	-	-	P	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
HFBHIDMB_01077	1.56e-80	yurZ	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HFBHIDMB_01078	4.46e-182	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HFBHIDMB_01079	3.53e-311	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	assembly protein SufD
HFBHIDMB_01080	1.14e-298	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HFBHIDMB_01081	6.26e-101	nifU	-	-	C	ko:K04488	-	ko00000	COG0822 NifU homolog involved in Fe-S cluster formation
HFBHIDMB_01082	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	FeS cluster assembly
HFBHIDMB_01083	1.05e-191	-	-	-	S	-	-	-	Pfam:Arm-DNA-bind_4
HFBHIDMB_01084	5.19e-56	-	-	-	E	-	-	-	Zn peptidase
HFBHIDMB_01085	7.06e-42	-	-	-	K	-	-	-	TRANSCRIPTIONal
HFBHIDMB_01086	8.19e-26	-	-	-	-	-	-	-	-
HFBHIDMB_01087	1.04e-31	-	-	-	-	-	-	-	-
HFBHIDMB_01093	1.09e-112	-	-	-	S	ko:K07741	-	ko00000	Phage regulatory protein Rha (Phage_pRha)
HFBHIDMB_01096	6.98e-65	-	-	-	L	-	-	-	primosome component and related proteins
HFBHIDMB_01097	1.72e-18	-	-	-	S	-	-	-	Loader and inhibitor of phage G40P
HFBHIDMB_01098	5.4e-211	-	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	replicative DNA helicase
HFBHIDMB_01099	6.24e-30	-	-	-	-	-	-	-	-
HFBHIDMB_01100	1.74e-11	-	-	-	S	-	-	-	Phage-like element PBSX protein XtrA
HFBHIDMB_01101	9.94e-67	-	-	-	M	-	-	-	ArpU family transcriptional regulator
HFBHIDMB_01102	4.94e-34	cotD	-	-	S	ko:K06327	-	ko00000	Inner spore coat protein D
HFBHIDMB_01106	1.34e-77	-	-	-	L	-	-	-	Terminase, small subunit
HFBHIDMB_01107	0.0	terL	-	-	S	-	-	-	Terminase
HFBHIDMB_01109	1.55e-215	-	-	-	S	-	-	-	portal protein
HFBHIDMB_01110	2.28e-93	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
HFBHIDMB_01111	7.3e-170	-	-	-	S	-	-	-	capsid protein
HFBHIDMB_01112	9.25e-13	-	-	-	-	-	-	-	-
HFBHIDMB_01114	1.42e-38	-	-	-	S	-	-	-	Phage head-tail joining protein
HFBHIDMB_01115	1.17e-43	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
HFBHIDMB_01117	2.55e-36	-	-	-	S	-	-	-	Phage tail tube protein
HFBHIDMB_01120	0.0	-	-	-	D	-	-	-	Phage tail tape measure protein
HFBHIDMB_01122	1.51e-134	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Prophage endopeptidase tail
HFBHIDMB_01123	1.84e-315	-	-	-	-	-	-	-	-
HFBHIDMB_01124	2.17e-238	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
HFBHIDMB_01127	2.55e-74	-	-	-	S	-	-	-	Bacteriophage holin family
HFBHIDMB_01128	1.44e-148	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
HFBHIDMB_01129	9.44e-85	-	-	-	S	-	-	-	Immunity protein 70
HFBHIDMB_01130	2.12e-238	-	-	-	A	ko:K21491	-	ko00000,ko01000,ko02048	Pre-toxin TG
HFBHIDMB_01131	1.43e-161	rapH	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Tetratricopeptide repeat
HFBHIDMB_01134	5.06e-86	yurT	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HFBHIDMB_01135	3.35e-56	-	-	-	-	-	-	-	-
HFBHIDMB_01137	4.87e-260	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	COG0665 Glycine D-amino acid oxidases (deaminating)
HFBHIDMB_01138	1.2e-87	yurQ	-	-	L	-	-	-	COG0322 Nuclease subunit of the excinuclease complex
HFBHIDMB_01139	5.27e-235	frlB	-	-	M	ko:K10708	-	ko00000,ko01000	Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
HFBHIDMB_01140	9.59e-306	yurO	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
HFBHIDMB_01141	1.44e-198	yurN	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HFBHIDMB_01142	1.94e-216	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
HFBHIDMB_01143	7.86e-208	-	2.7.1.218	-	G	ko:K10710	-	ko00000,ko01000	pfkB family carbohydrate kinase
HFBHIDMB_01144	8.71e-175	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
HFBHIDMB_01145	2.95e-263	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HFBHIDMB_01146	4.42e-216	bsn	-	-	L	-	-	-	Ribonuclease
HFBHIDMB_01147	3.96e-293	pucF	3.5.3.9	-	E	ko:K02083	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000,ko01002	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HFBHIDMB_01148	5.74e-304	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
HFBHIDMB_01149	4.85e-232	pucA	1.17.1.4	-	O	ko:K00087,ko:K07402	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HFBHIDMB_01150	7.22e-142	pucB	1.17.1.4, 2.7.7.76	-	S	ko:K00087,ko:K07141	ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120	ko00000,ko00001,ko00002,ko01000	MobA-like NTP transferase domain
HFBHIDMB_01151	1.23e-187	pucC	1.17.1.4, 1.2.5.3	-	C	ko:K00087,ko:K03519	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
HFBHIDMB_01152	0.0	pucD	1.17.1.4	-	C	ko:K00087	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
HFBHIDMB_01153	2.95e-123	-	1.17.1.4, 1.2.5.3	-	C	ko:K00087,ko:K03518	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
HFBHIDMB_01154	1.47e-72	pucM	3.5.2.17	-	S	ko:K07127	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
HFBHIDMB_01155	0.0	-	1.7.3.3, 4.1.1.97	-	Q	ko:K16838	ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
HFBHIDMB_01156	1.84e-282	pbuX	-	-	F	ko:K16169,ko:K16170	-	ko00000,ko02000	xanthine
HFBHIDMB_01157	6.93e-299	pbuX	-	-	F	ko:K03458,ko:K16169,ko:K16170	-	ko00000,ko02000	Permease family
HFBHIDMB_01158	0.0	pucR	-	-	QT	ko:K09684	-	ko00000,ko03000	COG2508 Regulator of polyketide synthase expression
HFBHIDMB_01159	0.0	allB	3.5.2.5	-	F	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
HFBHIDMB_01160	5.95e-77	yunG	-	-	-	-	-	-	-
HFBHIDMB_01161	7.07e-219	yunF	-	-	S	-	-	-	Protein of unknown function DUF72
HFBHIDMB_01162	1.86e-180	yunE	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HFBHIDMB_01163	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HFBHIDMB_01164	8.06e-64	yunC	-	-	S	-	-	-	Domain of unknown function (DUF1805)
HFBHIDMB_01165	3.49e-169	yunB	-	-	S	-	-	-	Sporulation protein YunB (Spo_YunB)
HFBHIDMB_01166	2.66e-252	lytH	-	-	M	ko:K21472	-	ko00000,ko01000,ko01002,ko01011	Peptidase, M23
HFBHIDMB_01167	1.37e-215	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HFBHIDMB_01168	2.71e-144	yutC	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HFBHIDMB_01169	3.2e-63	yutD	-	-	S	-	-	-	protein conserved in bacteria
HFBHIDMB_01170	2.38e-99	yutE	-	-	S	-	-	-	Protein of unknown function DUF86
HFBHIDMB_01171	3.69e-183	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HFBHIDMB_01172	2.26e-101	yutG	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
HFBHIDMB_01173	4.63e-255	yutH	-	-	S	-	-	-	Spore coat protein
HFBHIDMB_01174	6.79e-307	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HFBHIDMB_01175	1.14e-251	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HFBHIDMB_01176	2.57e-221	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HFBHIDMB_01177	0.0	yuxL	3.4.19.1	-	EU	ko:K01303	-	ko00000,ko01000,ko01002	peptidase
HFBHIDMB_01178	1.03e-46	yutI	-	-	O	-	-	-	COG0694 Thioredoxin-like proteins and domains
HFBHIDMB_01179	2.7e-74	yuzD	-	-	S	-	-	-	protein conserved in bacteria
HFBHIDMB_01180	1.12e-253	yutJ	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HFBHIDMB_01181	1.74e-52	yuzB	-	-	S	-	-	-	Belongs to the UPF0349 family
HFBHIDMB_01182	6.25e-270	yutK	-	-	F	ko:K03317	-	ko00000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HFBHIDMB_01183	2.25e-207	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HFBHIDMB_01184	6.81e-83	erpA	-	-	S	ko:K13628	-	ko00000,ko03016	Belongs to the HesB IscA family
HFBHIDMB_01185	1.39e-115	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HFBHIDMB_01186	2.84e-149	paiB	-	-	K	ko:K07734	-	ko00000,ko03000	Putative FMN-binding domain
HFBHIDMB_01187	3.7e-234	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HFBHIDMB_01189	1.16e-240	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	reductase
HFBHIDMB_01190	4.16e-301	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HFBHIDMB_01191	9.78e-47	yuiB	-	-	S	-	-	-	Putative membrane protein
HFBHIDMB_01192	1.5e-149	yuiC	-	-	S	-	-	-	protein conserved in bacteria
HFBHIDMB_01193	8.63e-102	yuiD	-	-	S	ko:K09775	-	ko00000	protein conserved in bacteria
HFBHIDMB_01194	0.0	pepA	3.4.11.1	-	E	ko:K01255	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HFBHIDMB_01195	4.25e-278	yuiF	-	-	S	ko:K07084	-	ko00000,ko02000	antiporter
HFBHIDMB_01196	8.33e-125	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Biotin biosynthesis protein
HFBHIDMB_01197	2.36e-157	yuiH	-	-	S	-	-	-	Oxidoreductase molybdopterin binding domain
HFBHIDMB_01198	1.04e-211	eSD	-	-	S	ko:K07017	-	ko00000	Putative esterase
HFBHIDMB_01199	2.89e-178	dhbA	1.3.1.28	-	IQ	ko:K00216	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HFBHIDMB_01200	2.45e-289	dhbC	5.4.4.2	-	HQ	ko:K02361	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
HFBHIDMB_01201	0.0	entE	2.7.7.58, 6.3.2.14	-	Q	ko:K02363,ko:K04783	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	2,3-dihydroxybenzoate-AMP ligase
HFBHIDMB_01202	6.09e-226	dhbB	3.3.2.1, 6.3.2.14	-	Q	ko:K01252	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	Isochorismatase family
HFBHIDMB_01203	0.0	dhbF	-	-	Q	ko:K04780	ko01053,map01053	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HFBHIDMB_01204	2.02e-47	mbtH	-	-	S	ko:K05375	ko00261,ko01130,map00261,map01130	ko00000,ko00001,ko00002	MbtH-like protein
HFBHIDMB_01205	1.2e-168	yukJ	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2278)
HFBHIDMB_01206	6.66e-261	ald	1.4.1.1	-	E	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
HFBHIDMB_01207	5.72e-290	yukF	-	-	QT	-	-	-	Transcriptional regulator
HFBHIDMB_01208	3.93e-60	yukE	-	-	S	-	-	-	Belongs to the WXG100 family
HFBHIDMB_01209	1.93e-54	yukD	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukD
HFBHIDMB_01210	3.93e-270	essB	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
HFBHIDMB_01211	0.0	essC	-	-	D	ko:K03466	-	ko00000,ko03036	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HFBHIDMB_01212	0.0	yueB	-	-	S	-	-	-	type VII secretion protein EsaA
HFBHIDMB_01213	1.78e-96	yueC	-	-	S	-	-	-	Family of unknown function (DUF5383)
HFBHIDMB_01214	3.53e-170	yueD	1.1.1.320	-	IQ	ko:K16216	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HFBHIDMB_01215	1.91e-125	yueE	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
HFBHIDMB_01216	8.4e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF2642)
HFBHIDMB_01217	6.59e-92	-	-	-	S	-	-	-	Protein of unknown function (DUF2283)
HFBHIDMB_01218	1.35e-244	yueF	-	-	S	-	-	-	transporter activity
HFBHIDMB_01219	1.19e-41	yueG	-	-	S	ko:K06299	-	ko00000	Spore germination protein gerPA/gerPF
HFBHIDMB_01220	1.63e-52	yueH	-	-	S	-	-	-	YueH-like protein
HFBHIDMB_01221	3.11e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HFBHIDMB_01222	2.69e-133	pncA	-	-	Q	ko:K16788	-	ko00000,ko02000	COG1335 Amidases related to nicotinamidase
HFBHIDMB_01223	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HFBHIDMB_01224	2.92e-298	yuxH	-	-	T	-	-	-	signal transduction protein containing EAL and modified HD-GYP domains
HFBHIDMB_01225	4.38e-09	yuzC	-	-	-	-	-	-	-
HFBHIDMB_01226	6.29e-10	-	-	-	S	-	-	-	DegQ (SacQ) family
HFBHIDMB_01227	7.01e-183	comQ	-	-	H	ko:K02251	ko02024,map02024	ko00000,ko00001,ko02044	Belongs to the FPP GGPP synthase family
HFBHIDMB_01229	0.0	comP	2.7.13.3	-	T	ko:K07680	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HFBHIDMB_01230	2.06e-150	comA	-	-	K	ko:K07691	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HFBHIDMB_01231	7.81e-83	yuxO	-	-	Q	-	-	-	protein, possibly involved in aromatic compounds catabolism
HFBHIDMB_01232	8.49e-79	mrpG	-	-	P	ko:K05571	-	ko00000,ko02000	COG1320 Multisubunit Na H antiporter, MnhG subunit
HFBHIDMB_01233	2.23e-51	mrpF	-	-	P	ko:K05570	-	ko00000,ko02000	Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HFBHIDMB_01234	2.12e-102	mrpE	-	-	P	ko:K05569	-	ko00000,ko02000	Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HFBHIDMB_01235	0.0	mrpD	-	-	CP	ko:K05568	-	ko00000,ko02000	Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HFBHIDMB_01236	1.72e-66	mrpC	-	-	P	ko:K05567	-	ko00000,ko02000	Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HFBHIDMB_01237	7.66e-91	mrpB	-	-	P	ko:K05566	-	ko00000,ko02000	Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HFBHIDMB_01238	0.0	mrpA	-	-	CP	ko:K05565	-	ko00000,ko02000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HFBHIDMB_01239	1.73e-22	-	-	-	-	-	-	-	-
HFBHIDMB_01240	7.99e-309	malP	-	-	C	ko:K11616	ko02020,map02020	ko00000,ko00001	COG3493 Na citrate symporter
HFBHIDMB_01241	6.97e-215	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HFBHIDMB_01242	1.29e-236	yufP	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HFBHIDMB_01243	0.0	yufO	3.6.3.17	-	S	ko:K02056	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HFBHIDMB_01244	6.34e-254	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC-type transport system, periplasmic component surface lipoprotein
HFBHIDMB_01245	3.26e-162	dcuR	-	-	T	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
HFBHIDMB_01246	0.0	malK	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
HFBHIDMB_01247	4.19e-113	yufK	-	-	S	-	-	-	Family of unknown function (DUF5366)
HFBHIDMB_01248	1.92e-97	yuxK	-	-	S	-	-	-	protein conserved in bacteria
HFBHIDMB_01249	0.0	pbpD	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555,ko:K18770	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin-binding Protein
HFBHIDMB_01250	4.61e-244	yuxJ	-	-	EGP	-	-	-	Major facilitator superfamily
HFBHIDMB_01252	1.71e-149	kapD	-	-	L	ko:K06348	-	ko00000	the KinA pathway to sporulation
HFBHIDMB_01253	2.49e-91	kapB	-	-	G	ko:K06347	ko02020,map02020	ko00000,ko00001	Kinase associated protein B
HFBHIDMB_01254	1.76e-295	kinB2	2.7.13.3	-	T	ko:K07697	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HFBHIDMB_01255	9.13e-284	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HFBHIDMB_01256	1.53e-52	yugE	-	-	S	-	-	-	Domain of unknown function (DUF1871)
HFBHIDMB_01257	9.89e-201	yugF	-	-	I	-	-	-	Hydrolase
HFBHIDMB_01258	6.74e-112	alaR	-	-	K	-	-	-	Transcriptional regulator
HFBHIDMB_01259	1.56e-254	yugH	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Aminotransferase
HFBHIDMB_01260	5e-83	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
HFBHIDMB_01261	2.21e-46	yuzA	-	-	S	ko:K09779	-	ko00000	Domain of unknown function (DUF378)
HFBHIDMB_01262	8.16e-287	yugJ	-	-	C	ko:K19955	-	ko00000,ko01000	oxidoreductases, Fe-dependent alcohol dehydrogenase family
HFBHIDMB_01263	5.56e-291	yugK	-	-	C	ko:K19955	-	ko00000,ko01000	Dehydrogenase
HFBHIDMB_01264	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HFBHIDMB_01266	4.22e-95	yugN	-	-	S	-	-	-	YugN-like family
HFBHIDMB_01267	2.92e-232	yugO	-	-	P	ko:K10716	-	ko00000,ko02000	COG1226 Kef-type K transport systems
HFBHIDMB_01268	5.01e-69	mstX	-	-	S	-	-	-	Membrane-integrating protein Mistic
HFBHIDMB_01269	6.2e-48	-	-	-	-	-	-	-	-
HFBHIDMB_01270	4.8e-150	yugP	-	-	S	ko:K06973	-	ko00000	Zn-dependent protease
HFBHIDMB_01271	5.09e-300	yugS	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HFBHIDMB_01272	0.0	yugT	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
HFBHIDMB_01273	3.63e-95	yugU	-	-	S	-	-	-	Uncharacterised protein family UPF0047
HFBHIDMB_01274	3.52e-48	-	-	-	-	-	-	-	-
HFBHIDMB_01275	2.41e-178	tgl	2.3.2.13	-	H	ko:K00686	-	ko00000,ko01000	Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
HFBHIDMB_01276	0.0	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HFBHIDMB_01277	1.2e-297	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HFBHIDMB_01278	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HFBHIDMB_01279	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HFBHIDMB_01280	0.0	yuxG	-	-	IQ	-	-	-	Class II Aldolase and Adducin N-terminal domain
HFBHIDMB_01281	1.42e-172	yulB	-	-	K	ko:K02530,ko:K22103	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
HFBHIDMB_01282	0.0	rhaB	2.7.1.5	-	G	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HFBHIDMB_01283	2.86e-72	rhaM	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Involved in the anomeric conversion of L-rhamnose
HFBHIDMB_01284	0.0	rhaA	2.7.1.5, 5.3.1.14	-	G	ko:K00848,ko:K01813	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Belongs to the rhamnose isomerase family
HFBHIDMB_01285	9.77e-231	yulF	-	-	S	ko:K22230	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
HFBHIDMB_01286	8.95e-255	yubA	-	-	S	-	-	-	transporter activity
HFBHIDMB_01287	1.73e-182	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HFBHIDMB_01289	6.82e-114	cdoA	1.13.11.20	-	S	ko:K00456	ko00270,ko00430,ko01100,map00270,map00430,map01100	ko00000,ko00001,ko01000	Cysteine dioxygenase type I
HFBHIDMB_01290	0.0	yubD	-	-	P	-	-	-	Major Facilitator Superfamily
HFBHIDMB_01291	2.18e-195	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HFBHIDMB_01292	3.31e-52	yubF	-	-	S	-	-	-	yiaA/B two helix domain
HFBHIDMB_01293	3.07e-300	-	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium
HFBHIDMB_01294	1.06e-156	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
HFBHIDMB_01295	5.83e-118	yuaB	-	-	-	-	-	-	-
HFBHIDMB_01296	3.39e-121	yuaC	-	-	K	ko:K22109	-	ko00000,ko03000	Belongs to the GbsR family
HFBHIDMB_01297	0.0	gbsA	1.2.1.8	-	C	ko:K00130	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HFBHIDMB_01298	1e-290	gbsB	1.1.1.1	-	C	ko:K11440	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
HFBHIDMB_01299	5.8e-137	yuaD	-	-	-	-	-	-	-
HFBHIDMB_01300	1.95e-109	yuaE	-	-	S	-	-	-	DinB superfamily
HFBHIDMB_01301	1.09e-105	yuaF	-	-	OU	-	-	-	Membrane protein implicated in regulation of membrane protease activity
HFBHIDMB_01302	4.54e-258	yuaG	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	protein conserved in bacteria
HFBHIDMB_01303	1.64e-120	-	-	-	M	-	-	-	FR47-like protein
HFBHIDMB_01304	2.52e-122	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
HFBHIDMB_01305	1.41e-266	bshA	-	GT4	M	ko:K00754	-	ko00000,ko01000	N-acetyl-alpha-D-glucosaminyl L-malate synthase
HFBHIDMB_01306	3.04e-278	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HFBHIDMB_01307	4.87e-234	birA	6.3.4.15	-	K	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HFBHIDMB_01308	4.85e-194	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HFBHIDMB_01309	3.69e-198	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HFBHIDMB_01310	4.16e-85	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HFBHIDMB_01311	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HFBHIDMB_01312	1.52e-32	ypmA	-	-	S	-	-	-	Protein of unknown function (DUF4264)
HFBHIDMB_01313	2.66e-102	ypmB	-	-	S	-	-	-	protein conserved in bacteria
HFBHIDMB_01314	5.1e-284	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HFBHIDMB_01315	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	asparaginyl-tRNA
HFBHIDMB_01316	6.62e-165	dnaD	-	-	L	ko:K02086	-	ko00000	DNA replication protein DnaD
HFBHIDMB_01317	3.57e-158	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HFBHIDMB_01318	1.95e-119	ypoC	-	-	-	-	-	-	-
HFBHIDMB_01319	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HFBHIDMB_01320	3.2e-150	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HFBHIDMB_01321	4.36e-239	yppC	-	-	S	-	-	-	Protein of unknown function (DUF2515)
HFBHIDMB_01324	3.11e-09	yppE	-	-	S	-	-	-	Bacterial domain of unknown function (DUF1798)
HFBHIDMB_01325	9.21e-11	-	-	-	S	-	-	-	YppF-like protein
HFBHIDMB_01326	8.72e-68	yppG	-	-	S	-	-	-	YppG-like protein
HFBHIDMB_01327	1.45e-93	hspX	-	-	O	ko:K06335,ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HFBHIDMB_01328	1.07e-109	ypqE	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	COG2190 Phosphotransferase system IIA components
HFBHIDMB_01329	0.0	yprA	-	-	L	ko:K06877	-	ko00000	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HFBHIDMB_01330	8.41e-300	yprB	-	-	L	ko:K07502	-	ko00000	RNase_H superfamily
HFBHIDMB_01331	9.4e-128	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HFBHIDMB_01332	2.97e-60	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HFBHIDMB_01333	2.84e-286	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HFBHIDMB_01335	0.0	ypvA	3.6.4.12	-	KL	ko:K03722	-	ko00000,ko01000,ko03400	COG1199 Rad3-related DNA helicases
HFBHIDMB_01336	1.88e-175	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HFBHIDMB_01337	1.2e-202	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HFBHIDMB_01338	3.18e-237	kdgR	-	-	K	ko:K02525	-	ko00000,ko03000	transcriptional
HFBHIDMB_01339	5.71e-237	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0524 Sugar kinases, ribokinase family
HFBHIDMB_01340	1.2e-131	kdgA	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	2-dehydro-3-deoxy-phosphogluconate aldolase
HFBHIDMB_01341	4.09e-224	kdgT	-	-	P	ko:K02526	-	ko00000,ko02000	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
HFBHIDMB_01342	0.0	ypwA	3.4.17.19	-	E	ko:K01299	-	ko00000,ko01000,ko01002	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HFBHIDMB_01343	1.11e-126	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HFBHIDMB_01344	1e-290	pbuX	-	-	F	ko:K03458,ko:K16169,ko:K16170	-	ko00000,ko02000	xanthine
HFBHIDMB_01345	2.63e-265	bcsA	-	-	Q	ko:K16167	-	ko00000,ko01008	Naringenin-chalcone synthase
HFBHIDMB_01346	9.54e-113	ypbQ	-	-	S	ko:K16168	-	ko00000,ko01008	protein conserved in bacteria
HFBHIDMB_01348	0.0	ypbR	-	-	S	-	-	-	Dynamin family
HFBHIDMB_01349	4.07e-52	ypbS	-	-	S	-	-	-	Protein of unknown function (DUF2533)
HFBHIDMB_01351	2.26e-213	ypcP	-	-	L	-	-	-	5'3' exonuclease
HFBHIDMB_01352	5.23e-05	-	-	-	-	ko:K06429	-	ko00000	-
HFBHIDMB_01353	1.6e-89	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease
HFBHIDMB_01354	5.2e-156	ypdP	-	-	S	ko:K09125	-	ko00000	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HFBHIDMB_01355	9.43e-162	ypeP	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	COG0328 Ribonuclease HI
HFBHIDMB_01356	7.99e-41	ypeQ	-	-	S	-	-	-	Zinc-finger
HFBHIDMB_01357	1.23e-39	-	-	-	S	-	-	-	Protein of unknown function (DUF2564)
HFBHIDMB_01358	1.17e-22	degR	-	-	-	-	-	-	-
HFBHIDMB_01359	5.12e-42	cspD	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
HFBHIDMB_01360	1.28e-276	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
HFBHIDMB_01361	6.09e-225	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HFBHIDMB_01362	3.66e-113	bsaA	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
HFBHIDMB_01363	2.94e-141	yagB	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
HFBHIDMB_01364	4.02e-204	ypgR	-	-	C	-	-	-	COG0694 Thioredoxin-like proteins and domains
HFBHIDMB_01365	0.0	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
HFBHIDMB_01366	9.69e-99	yphP	-	-	S	-	-	-	Belongs to the UPF0403 family
HFBHIDMB_01367	1.19e-184	ypiP	-	-	AJ	-	-	-	Putative SAM-dependent methyltransferase
HFBHIDMB_01368	1.41e-147	ypjP	-	-	S	-	-	-	YpjP-like protein
HFBHIDMB_01369	8.91e-121	ltrC	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
HFBHIDMB_01370	7.88e-121	dfrA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HFBHIDMB_01371	2.24e-141	ypkP	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HFBHIDMB_01372	8.03e-143	yplQ	-	-	S	ko:K11068	-	ko00000,ko02042	protein, Hemolysin III
HFBHIDMB_01373	1.63e-235	yplP	-	-	K	-	-	-	Transcriptional regulator
HFBHIDMB_01374	1.04e-309	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HFBHIDMB_01375	2.12e-53	ypmP	-	-	S	-	-	-	Protein of unknown function (DUF2535)
HFBHIDMB_01376	7.93e-140	ypmQ	-	-	S	ko:K07152	-	ko00000,ko03029	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
HFBHIDMB_01377	1.82e-178	ypmR	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HFBHIDMB_01378	1.95e-128	ypmS	-	-	S	-	-	-	protein conserved in bacteria
HFBHIDMB_01379	8.69e-40	ypmT	-	-	S	-	-	-	Uncharacterized ympT
HFBHIDMB_01380	9.99e-290	mepA	-	-	V	-	-	-	MATE efflux family protein
HFBHIDMB_01381	4.14e-94	ypoP	-	-	K	-	-	-	transcriptional
HFBHIDMB_01382	9.83e-133	msrB	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HFBHIDMB_01383	4.13e-102	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HFBHIDMB_01384	1.66e-157	-	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
HFBHIDMB_01385	9.41e-279	phy	3.1.3.8	-	I	ko:K01083	ko00562,map00562	ko00000,ko00001,ko01000	Myo-inositol-hexaphosphate 3-phosphohydrolase
HFBHIDMB_01386	2.69e-227	cgeB	-	-	S	ko:K06320	-	ko00000	Spore maturation protein
HFBHIDMB_01387	1.79e-82	cgeA	-	-	-	ko:K06319	-	ko00000	-
HFBHIDMB_01388	9.46e-29	cgeC	-	-	-	ko:K06321	-	ko00000	-
HFBHIDMB_01389	9.12e-13	cgeC	-	-	-	ko:K06321	-	ko00000	-
HFBHIDMB_01390	0.0	cgeD	-	-	M	ko:K06322	-	ko00000	maturation of the outermost layer of the spore
HFBHIDMB_01391	2.81e-184	yiiD	-	-	K	ko:K06323	-	ko00000	acetyltransferase
HFBHIDMB_01392	3.85e-314	yodT	-	-	H	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HFBHIDMB_01393	1.62e-159	atoD	2.8.3.8, 2.8.3.9	-	I	ko:K01034	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HFBHIDMB_01394	3.85e-152	atoA	2.8.3.8, 2.8.3.9	-	I	ko:K01035	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HFBHIDMB_01395	0.0	yodQ	3.5.1.16, 3.5.1.18	-	E	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetylornithine deacetylase
HFBHIDMB_01396	5.27e-197	yodP	2.3.1.264	-	K	ko:K21935	-	ko00000,ko01000	Acetyltransferase (GNAT) family
HFBHIDMB_01397	0.0	kamA	5.4.3.2	-	E	ko:K01843	ko00310,map00310	ko00000,ko00001,ko01000	lysine 2,3-aminomutase
HFBHIDMB_01398	3.44e-63	yokU	-	-	S	-	-	-	YokU-like protein, putative antitoxin
HFBHIDMB_01399	7.3e-50	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HFBHIDMB_01400	7.44e-159	yodN	-	-	-	-	-	-	-
HFBHIDMB_01402	5.18e-34	yozD	-	-	S	-	-	-	YozD-like protein
HFBHIDMB_01403	1.35e-136	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
HFBHIDMB_01404	1.17e-71	yodL	-	-	S	-	-	-	YodL-like
HFBHIDMB_01405	2.08e-12	-	-	-	-	-	-	-	-
HFBHIDMB_01406	1.68e-163	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
HFBHIDMB_01407	1.33e-189	yodJ	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
HFBHIDMB_01408	4.86e-41	yodI	-	-	-	-	-	-	-
HFBHIDMB_01409	1.24e-165	yodH	-	-	Q	-	-	-	Methyltransferase
HFBHIDMB_01410	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HFBHIDMB_01411	0.0	yodF	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HFBHIDMB_01412	2.36e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF3311)
HFBHIDMB_01413	8.09e-215	yodE	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
HFBHIDMB_01414	1.31e-146	yahD	-	-	S	ko:K06999	-	ko00000	Carboxylesterase
HFBHIDMB_01415	4.53e-139	yodC	-	-	C	-	-	-	nitroreductase
HFBHIDMB_01416	2.63e-73	yodB	-	-	K	-	-	-	transcriptional
HFBHIDMB_01417	5.64e-84	iolK	-	-	S	-	-	-	tautomerase
HFBHIDMB_01418	1.31e-289	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
HFBHIDMB_01419	1.95e-14	-	-	-	-	-	-	-	-
HFBHIDMB_01420	8.34e-104	yozR	-	-	S	-	-	-	COG0071 Molecular chaperone (small heat shock protein)
HFBHIDMB_01421	2.33e-207	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	-transporter
HFBHIDMB_01422	1.52e-57	-	-	-	-	-	-	-	-
HFBHIDMB_01423	2.32e-79	yojF	-	-	S	-	-	-	Protein of unknown function (DUF1806)
HFBHIDMB_01424	3.71e-161	yojG	-	-	S	ko:K22135	-	ko00000,ko01000	deacetylase
HFBHIDMB_01425	1.44e-193	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HFBHIDMB_01426	1.69e-312	norM	-	-	V	ko:K03327	-	ko00000,ko02000	Multidrug efflux pump
HFBHIDMB_01428	3.54e-140	dacB	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HFBHIDMB_01429	1.13e-293	yojK	-	-	CG	-	-	-	UDP-glucoronosyl and UDP-glucosyl transferase
HFBHIDMB_01430	1.3e-267	-	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
HFBHIDMB_01431	1.04e-141	sodC	1.15.1.1	-	P	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	ko00000,ko00001,ko01000	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HFBHIDMB_01432	1.55e-206	yojN	-	-	S	ko:K04748	-	ko00000	ATPase family associated with various cellular activities (AAA)
HFBHIDMB_01433	0.0	yojO	-	-	P	-	-	-	Von Willebrand factor
HFBHIDMB_01434	0.0	odhA	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HFBHIDMB_01435	3.16e-265	odhB	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HFBHIDMB_01436	3.31e-214	yocS	-	-	S	ko:K03453	-	ko00000	-transporter
HFBHIDMB_01437	4.35e-300	yocR	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HFBHIDMB_01438	3.35e-212	sodF	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Superoxide dismutase
HFBHIDMB_01439	0.0	sqhC	4.2.1.137	-	I	ko:K18115	-	ko00000,ko01000	COG1657 Squalene cyclase
HFBHIDMB_01440	0.0	dhaS	1.2.1.3, 1.2.1.39	-	C	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HFBHIDMB_01441	1.91e-42	yozC	-	-	-	-	-	-	-
HFBHIDMB_01442	2.17e-74	yozO	-	-	S	-	-	-	Bacterial PH domain
HFBHIDMB_01443	1.83e-49	yocN	-	-	-	-	-	-	-
HFBHIDMB_01444	2.94e-55	yozN	-	-	-	-	-	-	-
HFBHIDMB_01445	2.69e-114	yocM	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HFBHIDMB_01446	2.02e-43	-	-	-	-	-	-	-	-
HFBHIDMB_01447	3.02e-70	yocL	-	-	-	-	-	-	-
HFBHIDMB_01448	1.42e-107	yocK	-	-	T	-	-	-	general stress protein
HFBHIDMB_01449	5.95e-147	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HFBHIDMB_01450	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
HFBHIDMB_01451	6.78e-174	yocH	-	-	M	-	-	-	COG1388 FOG LysM repeat
HFBHIDMB_01452	4.71e-135	desR	-	-	T	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HFBHIDMB_01453	4.99e-252	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HFBHIDMB_01454	3.99e-258	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
HFBHIDMB_01455	6.44e-239	yocD	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	peptidase S66
HFBHIDMB_01456	1.32e-122	yocC	-	-	-	-	-	-	-
HFBHIDMB_01457	6.12e-184	-	-	-	-	-	-	-	-
HFBHIDMB_01458	3.97e-119	yozB	-	-	S	ko:K08976	-	ko00000	membrane
HFBHIDMB_01459	9.39e-157	yocA	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HFBHIDMB_01460	8.12e-69	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	transcriptional
HFBHIDMB_01461	5.2e-121	yobW	-	-	-	-	-	-	-
HFBHIDMB_01462	1.02e-219	yobV	-	-	K	-	-	-	WYL domain
HFBHIDMB_01463	8.64e-112	-	-	-	K	-	-	-	Bacterial transcription activator, effector binding domain
HFBHIDMB_01464	4.49e-168	yobT	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
HFBHIDMB_01465	1.26e-126	yobS	-	-	K	-	-	-	Transcriptional regulator
HFBHIDMB_01466	5.06e-181	-	-	-	J	-	-	-	FR47-like protein
HFBHIDMB_01467	2.39e-171	yobQ	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HFBHIDMB_01468	5.01e-69	csaA	-	-	J	ko:K06878	-	ko00000	tRNA-binding protein
HFBHIDMB_01469	0.0	iaaM	1.4.3.4	-	E	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	ko00000,ko00001,ko00002,ko01000	COG1231 Monoamine oxidase
HFBHIDMB_01470	3.34e-117	yokH	-	-	G	-	-	-	SMI1 / KNR4 family
HFBHIDMB_01471	0.0	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HFBHIDMB_01472	6.69e-112	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
HFBHIDMB_01473	1.66e-52	-	-	-	S	-	-	-	SMI1-KNR4 cell-wall
HFBHIDMB_01474	1.65e-127	yokK	-	-	S	-	-	-	SMI1 / KNR4 family
HFBHIDMB_01475	1.76e-126	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HFBHIDMB_01477	9.73e-49	-	-	-	-	-	-	-	-
HFBHIDMB_01478	9.74e-67	-	-	-	S	-	-	-	YolD-like protein
HFBHIDMB_01479	2.3e-294	-	-	-	S	-	-	-	damaged DNA binding
HFBHIDMB_01481	2.14e-17	-	-	-	Q	-	-	-	methyltransferase
HFBHIDMB_01482	4.01e-33	-	2.7.7.80	-	H	ko:K21029	ko04122,map04122	ko00000,ko00001,ko01000	ThiF family
HFBHIDMB_01483	0.000751	yabB	2.1.1.223	-	S	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
HFBHIDMB_01484	3.91e-52	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HFBHIDMB_01486	1.57e-121	-	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
HFBHIDMB_01488	9.95e-23	-	-	-	-	-	-	-	-
HFBHIDMB_01489	3.23e-86	yoaQ	-	-	S	-	-	-	Evidence 4 Homologs of previously reported genes of
HFBHIDMB_01490	3.12e-98	-	-	-	-	-	-	-	-
HFBHIDMB_01492	3.46e-10	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
HFBHIDMB_01493	4.98e-106	yoaW	-	-	-	-	-	-	-
HFBHIDMB_01494	2.82e-36	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
HFBHIDMB_01495	6.23e-131	-	-	-	S	-	-	-	Domain of unknown function (DUF3885)
HFBHIDMB_01496	3.25e-67	ynaF	-	-	-	-	-	-	-
HFBHIDMB_01503	1.15e-22	-	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
HFBHIDMB_01504	1.38e-172	-	-	-	-	-	-	-	-
HFBHIDMB_01505	2.49e-43	yoaF	-	-	-	-	-	-	-
HFBHIDMB_01507	2.11e-49	-	-	-	S	-	-	-	TM2 domain
HFBHIDMB_01508	7.53e-157	xlnB	3.2.1.8	-	G	ko:K01181	-	ko00000,ko01000	Glycosyl hydrolases family 11
HFBHIDMB_01509	0.0	pps	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphoenolpyruvate synthase
HFBHIDMB_01512	2.54e-215	penP	3.5.2.6	-	V	ko:K17836,ko:K18766	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	beta-lactamase
HFBHIDMB_01513	2.07e-148	lin0465	-	-	S	-	-	-	DJ-1/PfpI family
HFBHIDMB_01514	3.55e-47	yoaW	-	-	-	-	-	-	-
HFBHIDMB_01515	1.4e-42	yoaW	-	-	-	-	-	-	-
HFBHIDMB_01516	1.11e-202	yoaV	-	-	EG	-	-	-	EamA-like transporter family
HFBHIDMB_01517	5.48e-202	yoaU	-	-	K	-	-	-	LysR substrate binding domain
HFBHIDMB_01518	1.63e-190	yoaT	-	-	S	-	-	-	Protein of unknown function (DUF817)
HFBHIDMB_01519	1.21e-40	yozG	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
HFBHIDMB_01520	3.22e-98	yoaS	-	-	S	-	-	-	Protein of unknown function (DUF2975)
HFBHIDMB_01521	1.04e-217	yoaR	-	-	V	-	-	-	vancomycin resistance protein
HFBHIDMB_01522	2.09e-110	-	-	-	-	-	-	-	-
HFBHIDMB_01524	4.41e-293	oxdD	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
HFBHIDMB_01527	1.7e-169	yoqW	-	-	S	-	-	-	Belongs to the SOS response-associated peptidase family
HFBHIDMB_01528	9.68e-251	-	4.2.2.10	-	G	ko:K01732	-	ko00000,ko01000	Amb_all
HFBHIDMB_01529	1.79e-145	yoaK	-	-	S	-	-	-	Membrane
HFBHIDMB_01530	2.61e-171	yoaJ	-	-	G	ko:K20628	-	ko00000	Endoglucanase C-terminal domain subunit and related proteins
HFBHIDMB_01531	0.0	yoaI	1.14.14.9	-	Q	ko:K00483	ko00350,ko01120,ko01220,map00350,map01120,map01220	ko00000,ko00001,ko01000	COG2368 Aromatic ring hydroxylase
HFBHIDMB_01532	2.74e-283	yoaH	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	methyl-accepting chemotaxis protein
HFBHIDMB_01533	2.99e-55	-	-	-	S	-	-	-	Protein of unknown function (DUF4025)
HFBHIDMB_01534	1.46e-19	-	-	-	-	-	-	-	-
HFBHIDMB_01536	1.03e-44	yoaF	-	-	-	-	-	-	-
HFBHIDMB_01537	0.0	yoaE	-	-	C	-	-	-	belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HFBHIDMB_01538	9.23e-232	yoaD	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFBHIDMB_01539	0.0	lsrK	2.7.1.189	-	G	ko:K11216	ko02024,map02024	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
HFBHIDMB_01540	2.24e-300	yoaB	-	-	EGP	-	-	-	the major facilitator superfamily
HFBHIDMB_01541	2.06e-106	yoaA	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HFBHIDMB_01542	4.25e-173	yoxB	-	-	-	-	-	-	-
HFBHIDMB_01543	5.68e-53	yoxC	-	-	S	-	-	-	Bacterial protein of unknown function (DUF948)
HFBHIDMB_01544	2.28e-159	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
HFBHIDMB_01545	5.37e-79	rtp	-	-	K	-	-	-	Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
HFBHIDMB_01546	2.24e-184	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HFBHIDMB_01547	3.04e-258	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HFBHIDMB_01548	2.61e-205	gltC	-	-	K	ko:K09681	-	ko00000,ko03000	Transcriptional regulator
HFBHIDMB_01549	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
HFBHIDMB_01550	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HFBHIDMB_01551	1.63e-234	yogA	-	-	C	ko:K13955	-	ko00000	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HFBHIDMB_01552	2.41e-198	gltR1	-	-	K	ko:K21959	-	ko00000,ko03000	Transcriptional regulator
HFBHIDMB_01553	0.0	ggt	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
HFBHIDMB_01554	3.31e-47	yoeD	-	-	G	-	-	-	Helix-turn-helix domain
HFBHIDMB_01555	1.14e-124	-	-	-	L	-	-	-	Integrase
HFBHIDMB_01557	7.14e-128	yoeB	-	-	S	-	-	-	IseA DL-endopeptidase inhibitor
HFBHIDMB_01558	9.8e-313	yoeA	-	-	V	-	-	-	MATE efflux family protein
HFBHIDMB_01559	6.71e-241	yoxA	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HFBHIDMB_01560	0.0	dacC	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
HFBHIDMB_01561	0.0	spoVAF	-	-	EG	ko:K06408	-	ko00000	Stage V sporulation protein AF
HFBHIDMB_01562	1.85e-143	-	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
HFBHIDMB_01563	2.15e-75	spoVAEB	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
HFBHIDMB_01564	6.02e-246	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
HFBHIDMB_01565	6.71e-102	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
HFBHIDMB_01566	5.43e-90	spoVAB	-	-	S	ko:K06404	-	ko00000	Stage V sporulation protein AB
HFBHIDMB_01567	1.15e-143	spoVAA	-	-	S	ko:K06403	-	ko00000	Stage V sporulation protein AA
HFBHIDMB_01568	1.18e-174	sigF	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HFBHIDMB_01569	1.37e-99	spoIIAB	2.7.11.1	-	F	ko:K06379	-	ko00000,ko01000	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HFBHIDMB_01570	3e-76	spoIIAA	-	-	T	ko:K06378	-	ko00000	Belongs to the anti-sigma-factor antagonist family
HFBHIDMB_01571	2.37e-271	dacF	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HFBHIDMB_01572	1.39e-190	punA	2.4.2.1, 2.4.2.28	-	F	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	ko00000,ko00001,ko00002,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HFBHIDMB_01573	6.8e-294	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HFBHIDMB_01574	1.86e-212	xerD	-	-	L	ko:K04763	-	ko00000,ko03036	recombinase XerD
HFBHIDMB_01575	2.73e-50	-	-	-	S	-	-	-	Protein of unknown function (DUF4227)
HFBHIDMB_01576	2.26e-104	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HFBHIDMB_01577	2.78e-139	spoIIM	-	-	S	ko:K06384	-	ko00000	Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
HFBHIDMB_01578	7.27e-42	yqkK	-	-	-	-	-	-	-
HFBHIDMB_01579	1.47e-114	mleA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
HFBHIDMB_01580	1.93e-160	mleA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
HFBHIDMB_01581	0.0	mleN	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
HFBHIDMB_01582	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Aspartate ammonia-lyase
HFBHIDMB_01583	7.23e-238	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase
HFBHIDMB_01584	3.18e-77	ansR	-	-	K	-	-	-	Transcriptional regulator
HFBHIDMB_01585	1.19e-279	yqxK	-	-	L	-	-	-	DNA helicase
HFBHIDMB_01586	4.07e-120	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
HFBHIDMB_01587	8.21e-10	-	-	-	S	-	-	-	Protein of unknown function (DUF3936)
HFBHIDMB_01588	1.04e-214	yqkF	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
HFBHIDMB_01589	6.61e-26	yqkE	-	-	S	-	-	-	Protein of unknown function (DUF3886)
HFBHIDMB_01590	5.61e-221	yqkD	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
HFBHIDMB_01591	1.12e-53	yqkC	-	-	S	-	-	-	Protein of unknown function (DUF2552)
HFBHIDMB_01592	1.25e-72	yqkB	-	-	S	-	-	-	Belongs to the HesB IscA family
HFBHIDMB_01593	2.28e-248	yqkA	-	-	K	-	-	-	GrpB protein
HFBHIDMB_01594	2.25e-78	yqjZ	-	-	S	-	-	-	enzyme involved in biosynthesis of extracellular polysaccharides
HFBHIDMB_01595	5.46e-113	yqjY	-	-	K	ko:K06977	-	ko00000	acetyltransferase
HFBHIDMB_01596	3.23e-66	yqiX	-	-	S	-	-	-	YolD-like protein
HFBHIDMB_01597	1.46e-304	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HFBHIDMB_01599	7.96e-287	yqjV	-	-	G	-	-	-	Major Facilitator Superfamily
HFBHIDMB_01601	5.43e-95	yqjT	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HFBHIDMB_01602	6.6e-229	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HFBHIDMB_01603	0.0	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
HFBHIDMB_01604	6.89e-185	yqjQ	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HFBHIDMB_01605	5.2e-226	yqjP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
HFBHIDMB_01606	1.96e-189	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HFBHIDMB_01607	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
HFBHIDMB_01608	1.21e-245	namA	1.6.99.1	-	C	ko:K00354	-	ko00000,ko01000	Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HFBHIDMB_01609	3.17e-187	yqjL	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HFBHIDMB_01610	8.59e-27	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HFBHIDMB_01611	2.2e-221	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HFBHIDMB_01612	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HFBHIDMB_01613	0.0	gnd	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HFBHIDMB_01614	3.18e-300	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HFBHIDMB_01615	1.77e-32	yqzJ	-	-	-	-	-	-	-
HFBHIDMB_01616	3.36e-184	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HFBHIDMB_01617	5.7e-180	yqjF	-	-	S	ko:K09166	-	ko00000	Uncharacterized conserved protein (COG2071)
HFBHIDMB_01618	5.26e-259	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	COG2195 Di- and tripeptidases
HFBHIDMB_01619	0.0	yqjD	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HFBHIDMB_01620	2.22e-93	mce	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0346 Lactoylglutathione lyase and related lyases
HFBHIDMB_01622	9.84e-128	yqjB	-	-	S	-	-	-	protein conserved in bacteria
HFBHIDMB_01623	3.49e-221	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
HFBHIDMB_01624	2.47e-53	artM	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
HFBHIDMB_01625	5.84e-70	artM	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
HFBHIDMB_01626	8.94e-143	artQ	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
HFBHIDMB_01627	1.43e-175	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HFBHIDMB_01628	3.79e-101	yqiW	-	-	S	-	-	-	Belongs to the UPF0403 family
HFBHIDMB_01629	1.21e-213	bmrU	-	-	I	-	-	-	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HFBHIDMB_01630	1.79e-266	norA	-	-	EGP	ko:K08153,ko:K19576,ko:K19578	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
HFBHIDMB_01631	3.03e-193	-	-	-	K	ko:K19575	-	ko00000,ko00002,ko03000	helix_turn_helix, mercury resistance
HFBHIDMB_01632	2.09e-285	bkdB	2.3.1.12, 2.3.1.168	-	C	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HFBHIDMB_01633	6.92e-235	bfmBAB	1.2.4.4	-	C	ko:K00167,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HFBHIDMB_01634	1.11e-237	bfmBAA	1.2.4.4	-	C	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HFBHIDMB_01635	0.0	bfmBC	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HFBHIDMB_01636	1.96e-254	buk	2.7.2.7	-	C	ko:K00929	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Belongs to the acetokinase family
HFBHIDMB_01637	6.41e-261	ldh	1.4.1.9	-	E	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HFBHIDMB_01638	3.52e-198	ptb	2.3.1.19	-	C	ko:K00634	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	phosphate butyryltransferase
HFBHIDMB_01639	0.0	bkdR	-	-	KT	-	-	-	Transcriptional regulator
HFBHIDMB_01640	1.56e-46	yqzF	-	-	S	-	-	-	Protein of unknown function (DUF2627)
HFBHIDMB_01641	8.8e-209	prpB	4.1.3.30, 5.4.2.9	-	G	ko:K01841,ko:K03417	ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HFBHIDMB_01642	0.0	prpD	4.2.1.79	-	S	ko:K01720	ko00640,map00640	ko00000,ko00001,ko01000	2-methylcitrate dehydratase
HFBHIDMB_01643	1.85e-264	mmgD	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
HFBHIDMB_01644	2.86e-267	mmgC	-	-	I	ko:K18244	-	ko00000,ko01000	acyl-CoA dehydrogenase
HFBHIDMB_01645	6.9e-199	mmgB	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	Dehydrogenase
HFBHIDMB_01646	1.83e-277	mmgA	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
HFBHIDMB_01647	3.39e-168	yqiK	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HFBHIDMB_01648	9.4e-138	lytC_1	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Cell wall hydrolase autolysin
HFBHIDMB_01649	4.74e-37	-	-	-	-	-	-	-	-
HFBHIDMB_01650	1.15e-272	yqiG	-	-	C	-	-	-	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
HFBHIDMB_01652	1.89e-186	spo0A	-	-	KT	ko:K07699	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HFBHIDMB_01653	1.26e-303	spoIVB	3.4.21.116	-	M	ko:K06399	-	ko00000,ko01000,ko01002	Stage IV sporulation protein B
HFBHIDMB_01654	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HFBHIDMB_01655	3.08e-102	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HFBHIDMB_01656	1.77e-198	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	rRNA methylase
HFBHIDMB_01657	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HFBHIDMB_01658	4.2e-209	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HFBHIDMB_01659	1.09e-51	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HFBHIDMB_01660	3.55e-312	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HFBHIDMB_01661	1.07e-200	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HFBHIDMB_01662	4.8e-86	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HFBHIDMB_01663	9.55e-88	yqhY	-	-	S	-	-	-	protein conserved in bacteria
HFBHIDMB_01664	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HFBHIDMB_01665	3.21e-93	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HFBHIDMB_01666	9.92e-135	spoIIIAH	-	-	S	ko:K06397	-	ko00000	SpoIIIAH-like protein
HFBHIDMB_01667	1.08e-148	spoIIIAG	-	-	S	ko:K06396	-	ko00000	stage III sporulation protein AG
HFBHIDMB_01668	1.28e-131	spoIIIAF	-	-	S	ko:K06395	-	ko00000	Stage III sporulation protein AF (Spore_III_AF)
HFBHIDMB_01669	7.65e-257	spoIIIAE	-	-	S	ko:K06394	-	ko00000	stage III sporulation protein AE
HFBHIDMB_01670	1.93e-77	spoIIIAD	-	-	S	ko:K06393	-	ko00000	Stage III sporulation protein AD
HFBHIDMB_01671	1.63e-39	spoIIIAC	-	-	S	ko:K06392	-	ko00000	stage III sporulation protein AC
HFBHIDMB_01672	9.44e-110	spoIIIAB	-	-	S	ko:K06391	-	ko00000	Stage III sporulation protein
HFBHIDMB_01673	1.66e-216	spoIIIAA	-	-	S	ko:K06390	-	ko00000	stage III sporulation protein AA
HFBHIDMB_01674	6.96e-50	yqhV	-	-	S	-	-	-	Protein of unknown function (DUF2619)
HFBHIDMB_01675	4.8e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HFBHIDMB_01676	2.99e-249	yqhT	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
HFBHIDMB_01677	2.75e-100	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
HFBHIDMB_01678	9.37e-120	yqhR	-	-	S	-	-	-	Conserved membrane protein YqhR
HFBHIDMB_01679	2.98e-220	yqhQ	-	-	S	-	-	-	Protein of unknown function (DUF1385)
HFBHIDMB_01680	5.18e-81	yqhP	-	-	-	-	-	-	-
HFBHIDMB_01681	4.93e-210	yqhO	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
HFBHIDMB_01682	1.97e-97	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HFBHIDMB_01683	9.17e-204	lipM	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HFBHIDMB_01684	7.5e-83	yqhL	-	-	P	-	-	-	COG0607 Rhodanese-related sulfurtransferase
HFBHIDMB_01685	0.0	gcvPB	1.4.4.2	-	E	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HFBHIDMB_01686	0.0	gcvPA	1.4.4.2	-	E	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HFBHIDMB_01687	7.79e-261	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine
HFBHIDMB_01688	0.0	yqhH	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
HFBHIDMB_01689	9.14e-197	yqhG	-	-	S	-	-	-	Bacterial protein YqhG of unknown function
HFBHIDMB_01690	4.84e-34	sinI	-	-	S	ko:K06372	-	ko00000	Anti-repressor SinI
HFBHIDMB_01691	1.06e-71	sinR	-	-	K	ko:K19449	-	ko00000,ko03000	transcriptional
HFBHIDMB_01692	9e-182	tasA_1	-	-	S	ko:K06336	-	ko00000,ko01002	Cell division protein FtsN
HFBHIDMB_01693	4.27e-97	sipW	3.4.21.89	-	U	ko:K13280	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase
HFBHIDMB_01694	4.43e-153	yqxM	-	-	-	ko:K19433	-	ko00000	-
HFBHIDMB_01695	3.05e-69	yqzG	-	-	S	-	-	-	Protein of unknown function (DUF3889)
HFBHIDMB_01696	4.9e-37	yqzE	-	-	S	-	-	-	YqzE-like protein
HFBHIDMB_01697	1.08e-56	-	-	-	S	ko:K02249	-	ko00000,ko00002,ko02044	ComG operon protein 7
HFBHIDMB_01698	1.67e-45	comGF	-	-	U	ko:K02246,ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
HFBHIDMB_01699	7.23e-78	comGE	-	-	-	ko:K02247	-	ko00000,ko00002,ko02044	-
HFBHIDMB_01700	9.32e-92	gspH	-	-	NU	ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02035,ko02044	protein transport across the cell outer membrane
HFBHIDMB_01701	1.53e-62	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	Required for transformation and DNA binding
HFBHIDMB_01702	6.56e-214	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	COG1459 Type II secretory pathway, component PulF
HFBHIDMB_01703	2.13e-255	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HFBHIDMB_01704	2.13e-05	-	-	-	T	-	-	-	CBS domain
HFBHIDMB_01705	1.69e-230	yqxL	-	-	P	-	-	-	Mg2 transporter protein
HFBHIDMB_01706	1.36e-303	yqhB	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HFBHIDMB_01707	8.33e-191	yqhA	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HFBHIDMB_01709	7.79e-85	yqgZ	1.20.4.1	-	P	ko:K00537,ko:K16509	-	ko00000,ko01000	Belongs to the ArsC family
HFBHIDMB_01710	1.46e-50	yqgY	-	-	S	-	-	-	Protein of unknown function (DUF2626)
HFBHIDMB_01711	1.3e-156	yqgX	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	COG0491 Zn-dependent hydrolases, including glyoxylases
HFBHIDMB_01712	1.91e-31	yqgW	-	-	S	-	-	-	Protein of unknown function (DUF2759)
HFBHIDMB_01713	7.34e-66	yqgV	-	-	S	-	-	-	Thiamine-binding protein
HFBHIDMB_01714	5.42e-256	yqgU	-	-	-	-	-	-	-
HFBHIDMB_01715	4.14e-281	yqgT	3.4.19.11	-	E	ko:K01308	-	ko00000,ko01000,ko01002	Gamma-D-glutamyl-L-diamino acid endopeptidase
HFBHIDMB_01716	0.0	yqgS	2.7.8.20	-	M	ko:K01138,ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
HFBHIDMB_01717	2.31e-230	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
HFBHIDMB_01718	1.27e-43	yqgQ	-	-	S	-	-	-	Protein conserved in bacteria
HFBHIDMB_01719	0.0	gluP	3.4.21.105	-	O	ko:K19225	-	ko00000,ko01000,ko01002	membrane protein (homolog of Drosophila rhomboid)
HFBHIDMB_01720	3.38e-14	yqgO	-	-	-	-	-	-	-
HFBHIDMB_01721	4.27e-132	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HFBHIDMB_01722	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HFBHIDMB_01723	1.05e-252	yqgM	2.4.1.250	-	M	ko:K15521	-	ko00000,ko01000	Glycosyl transferases group 1
HFBHIDMB_01725	3.42e-68	yqzD	-	-	-	-	-	-	-
HFBHIDMB_01726	6.33e-93	yqzC	-	-	S	-	-	-	YceG-like family
HFBHIDMB_01727	1.57e-186	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HFBHIDMB_01728	9.78e-190	pstBA	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HFBHIDMB_01729	8.71e-201	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
HFBHIDMB_01730	7.11e-203	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HFBHIDMB_01731	4.32e-204	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HFBHIDMB_01732	0.0	pbpA	-	-	M	ko:K21465,ko:K21466	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
HFBHIDMB_01733	3.96e-293	yqgE	-	-	EGP	ko:K08222	-	ko00000,ko02000	Major facilitator superfamily
HFBHIDMB_01734	1.59e-148	sodA	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	radicals which are normally produced within the cells and which are toxic to biological systems
HFBHIDMB_01735	8.25e-101	yqgC	-	-	S	ko:K09793	-	ko00000	protein conserved in bacteria
HFBHIDMB_01736	2.74e-168	yqgB	-	-	S	-	-	-	Protein of unknown function (DUF1189)
HFBHIDMB_01737	1.35e-61	yqfZ	-	-	M	ko:K06417	-	ko00000	LysM domain
HFBHIDMB_01738	5.22e-257	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HFBHIDMB_01739	2.04e-81	yqfX	-	-	S	-	-	-	membrane
HFBHIDMB_01740	4.78e-141	yqfW	-	-	S	ko:K05967	-	ko00000	Belongs to the 5'(3')-deoxyribonucleotidase family
HFBHIDMB_01741	8.59e-107	zur	-	-	P	ko:K02076	-	ko00000,ko03000	Belongs to the Fur family
HFBHIDMB_01742	3.83e-199	yqfU	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HFBHIDMB_01743	3.01e-49	yqfT	-	-	S	-	-	-	Protein of unknown function (DUF2624)
HFBHIDMB_01744	1.04e-214	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HFBHIDMB_01745	3.13e-310	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HFBHIDMB_01746	3.36e-49	yqfQ	-	-	S	-	-	-	YqfQ-like protein
HFBHIDMB_01747	1.75e-226	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HFBHIDMB_01748	1.08e-268	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HFBHIDMB_01749	1.1e-146	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HFBHIDMB_01750	1.61e-81	cccA	-	-	C	ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
HFBHIDMB_01751	2.79e-254	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HFBHIDMB_01752	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HFBHIDMB_01753	6.03e-114	yqxD	-	-	S	ko:K09768	-	ko00000	Belongs to the UPF0178 family
HFBHIDMB_01754	6.38e-191	yqfL	2.7.11.33, 2.7.4.28	-	S	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HFBHIDMB_01755	3.29e-144	ccpN	-	-	K	-	-	-	CBS domain
HFBHIDMB_01756	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HFBHIDMB_01757	2.12e-222	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HFBHIDMB_01758	7.48e-187	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HFBHIDMB_01759	5.29e-27	-	-	-	S	-	-	-	YqzL-like protein
HFBHIDMB_01760	9.98e-215	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HFBHIDMB_01761	6.71e-93	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HFBHIDMB_01762	2.75e-79	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
HFBHIDMB_01763	8.68e-106	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HFBHIDMB_01764	0.0	yqfF	-	-	S	ko:K07037	-	ko00000	membrane-associated HD superfamily hydrolase
HFBHIDMB_01766	4.99e-224	phoH	-	-	T	ko:K06217	-	ko00000	Phosphate starvation-inducible protein PhoH
HFBHIDMB_01767	1.04e-242	yqfD	-	-	S	ko:K06438	-	ko00000	Stage IV sporulation
HFBHIDMB_01768	2.07e-60	yqfC	-	-	S	-	-	-	sporulation protein YqfC
HFBHIDMB_01769	5.2e-78	yqfB	-	-	-	-	-	-	-
HFBHIDMB_01770	4.35e-192	yqfA	-	-	S	-	-	-	UPF0365 protein
HFBHIDMB_01771	5.14e-288	yqeZ	-	-	O	ko:K07403	-	ko00000	COG1030 Membrane-bound serine protease (ClpP class)
HFBHIDMB_01772	2.25e-90	yqeY	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
HFBHIDMB_01773	1.03e-26	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HFBHIDMB_01774	2.8e-202	yqeW	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
HFBHIDMB_01775	0.0	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	ribosomal protein S12 methylthiotransferase
HFBHIDMB_01776	1.01e-180	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HFBHIDMB_01777	5.63e-226	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Methylates ribosomal protein L11
HFBHIDMB_01778	3.41e-257	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HFBHIDMB_01779	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HFBHIDMB_01780	4.36e-116	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HFBHIDMB_01781	1.65e-241	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HFBHIDMB_01782	2.9e-276	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
HFBHIDMB_01783	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HFBHIDMB_01784	6.28e-73	yqxA	-	-	S	-	-	-	Protein of unknown function (DUF3679)
HFBHIDMB_01785	9.53e-284	spoIIP	-	-	M	ko:K06385	-	ko00000	stage II sporulation protein P
HFBHIDMB_01786	4.16e-259	gpr	3.4.24.78	-	C	ko:K06012	-	ko00000,ko01000,ko01002	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HFBHIDMB_01787	4e-49	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HFBHIDMB_01788	9.55e-243	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HFBHIDMB_01789	2.36e-22	-	-	-	S	-	-	-	YqzM-like protein
HFBHIDMB_01790	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HFBHIDMB_01791	8.66e-167	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HFBHIDMB_01792	2.67e-136	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
HFBHIDMB_01793	2.35e-127	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	COG1555 DNA uptake protein and related DNA-binding proteins
HFBHIDMB_01794	2.69e-189	comER	-	-	E	ko:K02239	-	ko00000,ko00002,ko02044	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HFBHIDMB_01795	4.66e-177	yqeM	-	-	Q	-	-	-	Methyltransferase
HFBHIDMB_01796	1.14e-80	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HFBHIDMB_01797	4.81e-133	yqeK	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
HFBHIDMB_01798	2.47e-141	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HFBHIDMB_01799	8.95e-61	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein containing KH domain, possibly ribosomal protein
HFBHIDMB_01800	8.1e-199	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HFBHIDMB_01801	4.78e-273	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HFBHIDMB_01802	2.17e-123	yqeG	-	-	S	ko:K07015	-	ko00000	hydrolase of the HAD superfamily
HFBHIDMB_01804	1.84e-181	yqeF	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HFBHIDMB_01805	2.05e-177	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
HFBHIDMB_01806	8.6e-131	yqeD	-	-	S	-	-	-	SNARE associated Golgi protein
HFBHIDMB_01807	8.54e-214	yqeC	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconate dehydrogenase
HFBHIDMB_01808	5.21e-168	-	-	-	-	-	-	-	-
HFBHIDMB_01809	7.25e-97	nucB	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
HFBHIDMB_01810	1.1e-72	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HFBHIDMB_01811	0.0	-	-	-	L	ko:K06400	-	ko00000	Recombinase
HFBHIDMB_01812	9.82e-101	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Catalyzes the reduction of arsenate As(V) to arsenite As(III)
HFBHIDMB_01813	7.13e-233	arsB	-	-	P	ko:K03325	-	ko00000,ko02000	Arsenic resistance protein
HFBHIDMB_01814	2.56e-104	cadI	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HFBHIDMB_01815	1.53e-72	arsR	-	-	K	ko:K03892	-	ko00000,ko03000	ArsR family transcriptional regulator
HFBHIDMB_01816	5.5e-193	yqcI	-	-	S	ko:K09190	-	ko00000	YqcI/YcgG family
HFBHIDMB_01817	8.68e-120	-	-	-	S	-	-	-	Tetratricopeptide repeat
HFBHIDMB_01820	0.0	-	-	-	A	ko:K21491	-	ko00000,ko01000,ko02048	Pre-toxin TG
HFBHIDMB_01821	1.66e-136	-	-	-	S	ko:K21492	-	ko00000,ko02048	Suppressor of fused protein (SUFU)
HFBHIDMB_01823	5.4e-80	-	-	-	-	-	-	-	-
HFBHIDMB_01825	1.27e-182	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
HFBHIDMB_01826	8.36e-89	-	-	-	S	-	-	-	Bacteriophage holin family
HFBHIDMB_01827	1.36e-210	xepA	-	-	-	-	-	-	-
HFBHIDMB_01828	2.51e-28	-	-	-	-	-	-	-	-
HFBHIDMB_01829	1.38e-71	xkdW	-	-	S	-	-	-	XkdW protein
HFBHIDMB_01830	2.96e-246	-	-	-	-	-	-	-	-
HFBHIDMB_01831	4.62e-49	-	-	-	-	-	-	-	-
HFBHIDMB_01832	2.74e-126	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2313)
HFBHIDMB_01833	6.67e-239	-	-	-	S	-	-	-	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HFBHIDMB_01834	6.6e-91	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
HFBHIDMB_01835	8.16e-42	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
HFBHIDMB_01836	8.96e-226	xkdQ	-	-	G	-	-	-	NLP P60 protein
HFBHIDMB_01837	6.29e-154	xkdP	-	-	S	-	-	-	Lysin motif
HFBHIDMB_01838	0.0	xkdO	-	-	L	-	-	-	Transglycosylase SLT domain
HFBHIDMB_01839	1.12e-23	-	-	-	-	-	-	-	-
HFBHIDMB_01840	1.27e-89	-	-	-	S	-	-	-	Phage XkdN-like tail assembly chaperone protein, TAC
HFBHIDMB_01841	4.23e-99	xkdM	-	-	S	-	-	-	Phage tail tube protein
HFBHIDMB_01842	0.0	xkdK	-	-	S	-	-	-	Phage tail sheath C-terminal domain
HFBHIDMB_01843	1.21e-34	-	-	-	-	-	-	-	-
HFBHIDMB_01844	1.48e-98	yqbJ	-	-	-	-	-	-	-
HFBHIDMB_01845	8.84e-113	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
HFBHIDMB_01846	3.38e-83	yqbH	-	-	S	-	-	-	Domain of unknown function (DUF3599)
HFBHIDMB_01847	1.43e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF3199)
HFBHIDMB_01848	2.12e-60	-	-	-	S	-	-	-	YqbF, hypothetical protein domain
HFBHIDMB_01849	7.57e-215	xkdG	-	-	S	-	-	-	Phage capsid family
HFBHIDMB_01850	4.23e-158	yqbD	-	-	L	-	-	-	Putative phage serine protease XkdF
HFBHIDMB_01851	5.03e-90	-	-	-	S	-	-	-	Phage Mu protein F like protein
HFBHIDMB_01852	2.65e-196	-	-	-	S	-	-	-	Phage Mu protein F like protein
HFBHIDMB_01853	0.0	yqbA	-	-	S	-	-	-	portal protein
HFBHIDMB_01854	3.38e-315	yqaT	-	-	S	ko:K06909	-	ko00000	phage terminase, large subunit
HFBHIDMB_01855	7.73e-147	yqaS	-	-	L	-	-	-	DNA packaging
HFBHIDMB_01857	2.83e-99	yqaQ	-	-	L	-	-	-	Transposase
HFBHIDMB_01859	8.38e-42	yqaO	-	-	S	-	-	-	Phage-like element PBSX protein XtrA
HFBHIDMB_01860	1.28e-93	rusA	-	-	L	-	-	-	Endodeoxyribonuclease RusA
HFBHIDMB_01862	5.04e-207	yqaM	-	-	L	-	-	-	IstB-like ATP binding protein
HFBHIDMB_01863	5.29e-156	yqaL	-	-	L	-	-	-	DnaD domain protein
HFBHIDMB_01864	2.79e-192	recT	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
HFBHIDMB_01865	3.18e-213	yqaJ	-	-	L	-	-	-	YqaJ-like viral recombinase domain
HFBHIDMB_01869	1.04e-133	-	-	-	-	-	-	-	-
HFBHIDMB_01871	3.43e-49	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HFBHIDMB_01872	1.25e-74	-	-	-	K	-	-	-	sequence-specific DNA binding
HFBHIDMB_01874	8.73e-132	yqaC	-	-	F	-	-	-	adenylate kinase activity
HFBHIDMB_01875	1.58e-122	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
HFBHIDMB_01876	1.42e-78	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HFBHIDMB_01877	1.48e-81	psiE	-	-	S	ko:K13256	-	ko00000	Protein PsiE homolog
HFBHIDMB_01878	4.05e-303	yrkQ	-	-	T	-	-	-	Histidine kinase
HFBHIDMB_01879	7.15e-164	yrkP	-	-	T	ko:K02483	-	ko00000,ko02022	Transcriptional regulator
HFBHIDMB_01880	7.21e-281	yrkO	-	-	P	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
HFBHIDMB_01881	8.99e-133	yrkN	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HFBHIDMB_01882	4.7e-125	yrkL	-	-	S	ko:K11748	-	ko00000,ko02000	Flavodoxin-like fold
HFBHIDMB_01883	2.21e-102	-	-	-	S	-	-	-	Protein of unknown function with HXXEE motif
HFBHIDMB_01884	6.63e-162	yrkJ	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HFBHIDMB_01885	6.46e-49	yrkI	-	-	O	-	-	-	Belongs to the sulfur carrier protein TusA family
HFBHIDMB_01886	9.59e-269	yrkH	-	-	P	-	-	-	Rhodanese Homology Domain
HFBHIDMB_01887	0.000112	perX	-	-	S	-	-	-	DsrE/DsrF-like family
HFBHIDMB_01888	4.61e-126	yrkF	-	-	OP	-	-	-	Belongs to the sulfur carrier protein TusA family
HFBHIDMB_01889	6.83e-109	yrkE	-	-	O	-	-	-	DsrE/DsrF/DrsH-like family
HFBHIDMB_01890	4.38e-52	yrkD	-	-	S	-	-	-	protein conserved in bacteria
HFBHIDMB_01891	3.32e-28	-	-	-	-	-	-	-	-
HFBHIDMB_01892	1.28e-137	yrkC	-	-	G	-	-	-	Cupin domain
HFBHIDMB_01893	4.42e-185	bltR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HFBHIDMB_01894	2.17e-268	blt	-	-	EGP	ko:K08153,ko:K19578	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
HFBHIDMB_01895	2.16e-108	bltD	2.3.1.57	-	K	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	FR47-like protein
HFBHIDMB_01896	7.69e-293	yrkA	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HFBHIDMB_01897	2.45e-23	-	-	-	S	-	-	-	YrzO-like protein
HFBHIDMB_01898	2.84e-215	yrdR	-	-	EG	-	-	-	EamA-like transporter family
HFBHIDMB_01899	1.15e-202	-	-	-	K	-	-	-	Transcriptional regulator
HFBHIDMB_01900	1.23e-253	trkA	-	-	P	ko:K07222	-	ko00000	Oxidoreductase
HFBHIDMB_01901	6e-213	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	COG1230 Co Zn Cd efflux system component
HFBHIDMB_01903	2.03e-291	brnQ	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HFBHIDMB_01904	1.97e-66	azlD	-	-	E	-	-	-	Branched-chain amino acid transport protein (AzlD)
HFBHIDMB_01905	6.57e-176	azlC	-	-	E	-	-	-	AzlC protein
HFBHIDMB_01906	4.82e-103	bkdR	-	-	K	-	-	-	helix_turn_helix ASNC type
HFBHIDMB_01907	7.91e-55	yrdF	-	-	K	ko:K03623	-	ko00000	ribonuclease inhibitor
HFBHIDMB_01908	3.11e-289	cypA	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
HFBHIDMB_01910	2.11e-130	yrdC	-	-	Q	-	-	-	Isochorismatase family
HFBHIDMB_01911	1.04e-71	-	-	-	S	-	-	-	Protein of unknown function (DUF2568)
HFBHIDMB_01912	2.01e-118	yrdA	-	-	S	-	-	-	DinB family
HFBHIDMB_01913	8.54e-212	aadK	-	-	G	ko:K05593	-	ko00000,ko01000,ko01504	Streptomycin adenylyltransferase
HFBHIDMB_01914	4.23e-246	npd	1.13.12.16	-	S	ko:K00459	ko00910,map00910	ko00000,ko00001,ko01000	COG2070 Dioxygenases related to 2-nitropropane dioxygenase
HFBHIDMB_01915	1.56e-184	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HFBHIDMB_01916	2.39e-162	yrpD	-	-	S	-	-	-	Domain of unknown function, YrpD
HFBHIDMB_01917	2.34e-128	-	-	-	K	ko:K05799	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HFBHIDMB_01919	2.76e-266	-	-	-	P	-	-	-	Major Facilitator Superfamily
HFBHIDMB_01920	3.43e-145	-	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HFBHIDMB_01921	2.91e-192	-	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transketolase, pyrimidine binding domain
HFBHIDMB_01922	5.45e-176	-	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	COG3959 Transketolase, N-terminal subunit
HFBHIDMB_01924	7.88e-281	yfjF	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily
HFBHIDMB_01925	1.51e-85	napB	-	-	K	-	-	-	MarR family transcriptional regulator
HFBHIDMB_01926	7.31e-167	zinT	-	-	S	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
HFBHIDMB_01927	2.92e-120	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HFBHIDMB_01928	5.96e-240	yrpG	-	-	C	-	-	-	Aldo/keto reductase family
HFBHIDMB_01929	5.31e-286	yraO	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
HFBHIDMB_01930	2.97e-210	yraN	-	-	K	-	-	-	Transcriptional regulator
HFBHIDMB_01931	5.95e-263	yraM	-	-	S	-	-	-	PrpF protein
HFBHIDMB_01932	3.87e-200	csn	3.2.1.132	-	M	ko:K01233	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
HFBHIDMB_01933	1.45e-55	yraL	-	-	S	-	-	-	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HFBHIDMB_01934	6.66e-192	-	-	-	S	-	-	-	Alpha beta hydrolase
HFBHIDMB_01935	7.73e-79	-	-	-	T	-	-	-	sh3 domain protein
HFBHIDMB_01936	1.44e-79	-	-	-	T	-	-	-	sh3 domain protein
HFBHIDMB_01937	3.15e-85	-	-	-	E	-	-	-	Glyoxalase-like domain
HFBHIDMB_01938	4.19e-50	yraG	-	-	-	ko:K06440	-	ko00000	-
HFBHIDMB_01939	9.61e-84	yraF	-	-	M	-	-	-	Spore coat protein
HFBHIDMB_01940	4.84e-279	adhB	1.1.1.1, 1.1.1.284, 1.2.1.46	-	E	ko:K00121,ko:K00148	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HFBHIDMB_01941	1.23e-35	yraE	-	-	-	ko:K06440	-	ko00000	-
HFBHIDMB_01942	7.23e-66	yraD	-	-	M	ko:K06439	-	ko00000	Spore coat protein
HFBHIDMB_01943	1.83e-67	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
HFBHIDMB_01944	2.9e-10	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	peroxiredoxin activity
HFBHIDMB_01945	4.81e-253	adhA	-	-	C	ko:K13979	-	ko00000,ko01000	alcohol dehydrogenase
HFBHIDMB_01946	2.25e-116	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
HFBHIDMB_01947	0.0	sacC	3.2.1.80	-	G	ko:K03332	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
HFBHIDMB_01948	1.39e-192	levG	-	-	G	ko:K02771,ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
HFBHIDMB_01949	6.11e-168	levF	-	-	G	ko:K02746,ko:K02795,ko:K11196	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
HFBHIDMB_01950	7.63e-107	ptnA	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11195	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system mannose fructose sorbose family
HFBHIDMB_01951	5.36e-97	levD	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11194	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HFBHIDMB_01952	0.0	levR	-	-	K	-	-	-	PTS system fructose IIA component
HFBHIDMB_01953	0.0	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
HFBHIDMB_01954	4.63e-136	yrhP	-	-	E	-	-	-	LysE type translocator
HFBHIDMB_01955	5.9e-194	yrhO	-	-	K	-	-	-	Archaeal transcriptional regulator TrmB
HFBHIDMB_01956	5.77e-113	sigV	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HFBHIDMB_01957	1.12e-187	rsiV	-	-	S	-	-	-	Protein of unknown function (DUF3298)
HFBHIDMB_01958	0.0	oatA	-	-	I	-	-	-	Acyltransferase family
HFBHIDMB_01959	6.32e-59	yrhK	-	-	S	-	-	-	YrhK-like protein
HFBHIDMB_01960	0.0	yrhJ	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
HFBHIDMB_01961	2.26e-135	-	-	-	K	ko:K22106	-	ko00000,ko03000	Tetracycline repressor, C-terminal all-alpha domain
HFBHIDMB_01962	8.67e-124	yrhH	-	-	Q	-	-	-	methyltransferase
HFBHIDMB_01963	9.39e-08	-	-	-	S	-	-	-	Probable sporulation protein (Bac_small_yrzI)
HFBHIDMB_01964	1.38e-183	yrhG	-	-	P	ko:K21993	-	ko00000,ko02000	Formate nitrite
HFBHIDMB_01965	4.41e-80	yrhF	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
HFBHIDMB_01966	0.0	yjgC	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase (NAD+) activity
HFBHIDMB_01967	6.05e-103	yrhD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
HFBHIDMB_01968	6.93e-49	yrhC	-	-	S	-	-	-	YrhC-like protein
HFBHIDMB_01969	8.55e-269	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HFBHIDMB_01970	1.66e-216	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Cysteine synthase
HFBHIDMB_01971	1.97e-161	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HFBHIDMB_01972	3.44e-153	yrrT	-	-	Q	ko:K17462	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Could be a S-adenosyl-L-methionine-dependent methyltransferase
HFBHIDMB_01973	4.94e-36	yrzA	-	-	S	-	-	-	Protein of unknown function (DUF2536)
HFBHIDMB_01974	1.42e-102	yrrS	-	-	S	-	-	-	Protein of unknown function (DUF1510)
HFBHIDMB_01975	0.0	pbpI	-	-	M	ko:K21468	-	ko00000,ko01011	Penicillin-binding Protein
HFBHIDMB_01976	1.14e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HFBHIDMB_01977	4.51e-148	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HFBHIDMB_01978	4.62e-313	yrrO	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	COG0826 Collagenase and related proteases
HFBHIDMB_01979	6.3e-222	yrrN	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
HFBHIDMB_01980	1.98e-154	yrrM	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-methyltransferase
HFBHIDMB_01981	7.51e-242	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HFBHIDMB_01982	2.94e-60	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HFBHIDMB_01983	5.49e-93	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HFBHIDMB_01984	2.22e-55	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HFBHIDMB_01985	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HFBHIDMB_01986	1.25e-241	yrrI	-	-	S	-	-	-	AI-2E family transporter
HFBHIDMB_01987	2.21e-168	glnQ	-	-	E	ko:K09972,ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
HFBHIDMB_01988	1.01e-184	glnH	-	-	ET	ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HFBHIDMB_01989	3.24e-139	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HFBHIDMB_01990	9.26e-140	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HFBHIDMB_01991	5.38e-12	-	-	-	S	-	-	-	Protein of unknown function (DUF3918)
HFBHIDMB_01992	8.4e-42	yrzR	-	-	-	-	-	-	-
HFBHIDMB_01993	1.44e-107	yrrD	-	-	S	-	-	-	protein conserved in bacteria
HFBHIDMB_01994	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HFBHIDMB_01995	1.02e-38	yrrB	-	-	S	-	-	-	COG0457 FOG TPR repeat
HFBHIDMB_01996	5.64e-279	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HFBHIDMB_01997	2.98e-269	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
HFBHIDMB_01998	8.12e-93	cymR	-	-	K	ko:K17472	-	ko00000,ko03000	Transcriptional regulator
HFBHIDMB_01999	6.69e-301	rarA	-	-	L	ko:K07478	-	ko00000	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HFBHIDMB_02000	2.29e-176	yrvM	-	-	H	ko:K22132	-	ko00000,ko03016	COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HFBHIDMB_02001	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HFBHIDMB_02002	7.06e-309	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HFBHIDMB_02004	0.0	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	COG3103 SH3 domain protein
HFBHIDMB_02005	1.36e-90	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HFBHIDMB_02006	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HFBHIDMB_02007	2.53e-118	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HFBHIDMB_02008	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HFBHIDMB_02009	1.07e-64	yrvD	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
HFBHIDMB_02010	2.65e-113	trkA1	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
HFBHIDMB_02011	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HFBHIDMB_02012	5.53e-65	yrzD	-	-	S	-	-	-	Post-transcriptional regulator
HFBHIDMB_02013	0.0	spoVB	-	-	S	ko:K06409	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HFBHIDMB_02014	5.83e-143	yrbG	-	-	S	-	-	-	membrane
HFBHIDMB_02015	1.46e-96	yrzE	-	-	S	-	-	-	Protein of unknown function (DUF3792)
HFBHIDMB_02016	1.24e-52	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit YajC
HFBHIDMB_02017	4.74e-292	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HFBHIDMB_02018	6.03e-248	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HFBHIDMB_02019	2.91e-30	yrzS	-	-	S	-	-	-	Protein of unknown function (DUF2905)
HFBHIDMB_02020	9.14e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HFBHIDMB_02021	2.84e-137	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HFBHIDMB_02022	1.85e-120	bofC	-	-	S	ko:K06318	-	ko00000	BofC C-terminal domain
HFBHIDMB_02023	0.0	csbX	-	-	EGP	-	-	-	the major facilitator superfamily
HFBHIDMB_02024	4.59e-247	idhA	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
HFBHIDMB_02025	1.91e-151	yrzF	-	-	T	-	-	-	serine threonine protein kinase
HFBHIDMB_02027	6.26e-68	-	-	-	S	-	-	-	Family of unknown function (DUF5412)
HFBHIDMB_02028	0.0	yrbD	-	-	E	ko:K03310	-	ko00000	Sodium alanine symporter
HFBHIDMB_02029	8.63e-165	yebC	-	-	K	-	-	-	transcriptional regulatory protein
HFBHIDMB_02030	2.55e-70	-	-	-	S	ko:K06345	-	ko00000	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HFBHIDMB_02031	2.43e-217	safA	-	-	M	ko:K06370	-	ko00000	spore coat assembly protein SafA
HFBHIDMB_02032	1.32e-271	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HFBHIDMB_02033	8.4e-201	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NadC ModD family
HFBHIDMB_02034	0.0	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
HFBHIDMB_02035	2.36e-290	nifS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
HFBHIDMB_02036	5.02e-123	yrxA	-	-	S	ko:K07105	-	ko00000	small molecule binding protein (contains 3H domain)
HFBHIDMB_02037	2.53e-149	-	-	GH19	M	ko:K03791	-	ko00000	Lysin motif
HFBHIDMB_02038	4.12e-73	-	-	-	-	-	-	-	-
HFBHIDMB_02039	1.46e-267	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HFBHIDMB_02040	6.86e-228	mpr	-	-	M	-	-	-	Belongs to the peptidase S1B family
HFBHIDMB_02042	5.56e-214	-	-	-	S	-	-	-	Alpha/beta hydrolase family
HFBHIDMB_02043	2.81e-123	pssA	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HFBHIDMB_02044	7.07e-112	ybfM	-	-	S	-	-	-	SNARE associated Golgi protein
HFBHIDMB_02045	2.06e-188	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
HFBHIDMB_02046	1.58e-59	ybfN	-	-	-	-	-	-	-
HFBHIDMB_02047	0.0	-	-	-	S	ko:K06880	-	ko00000,ko01000,ko01504	Erythromycin esterase
HFBHIDMB_02048	6.73e-244	ybfQ	-	-	S	ko:K07146	-	ko00000	Belongs to the UPF0176 family
HFBHIDMB_02049	4.25e-273	gltP	-	-	C	ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HFBHIDMB_02050	0.0	ptsG	2.7.1.199	-	G	ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HFBHIDMB_02051	3.52e-173	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HFBHIDMB_02052	2.91e-165	-	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
HFBHIDMB_02054	3.44e-256	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HFBHIDMB_02055	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HFBHIDMB_02056	1.29e-233	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine
HFBHIDMB_02057	0.0	agcS	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
HFBHIDMB_02058	5.08e-237	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HFBHIDMB_02059	3.55e-294	glnJ	2.7.13.3	-	T	ko:K07717	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HFBHIDMB_02060	9.96e-217	glnL	-	-	T	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Regulator
HFBHIDMB_02061	4.1e-222	ycbC	4.2.1.41	-	EM	ko:K01707	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	5-dehydro-4-deoxyglucarate dehydratase activity
HFBHIDMB_02062	0.0	ycbD	-	-	C	ko:K22187	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HFBHIDMB_02063	0.0	gudP	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HFBHIDMB_02064	0.0	gudD	4.2.1.40	-	M	ko:K01706	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
HFBHIDMB_02065	2.3e-161	ycbG	-	-	K	ko:K05799	-	ko00000,ko03000	FCD
HFBHIDMB_02066	0.0	garD	4.2.1.42, 4.2.1.7	-	G	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
HFBHIDMB_02067	1.74e-222	ycbJ	-	-	S	ko:K06979	-	br01600,ko00000,ko00002,ko01504	Macrolide 2'-phosphotransferase
HFBHIDMB_02068	8.73e-33	rtpA	-	-	K	-	-	-	Tryptophan RNA-binding attenuator protein inhibitory protein
HFBHIDMB_02069	9.95e-216	eamA1	-	-	EG	-	-	-	spore germination
HFBHIDMB_02070	2.61e-160	ycbL	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HFBHIDMB_02071	6.21e-214	ycbM	-	-	T	-	-	-	Histidine kinase
HFBHIDMB_02072	5.32e-213	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFBHIDMB_02073	4.25e-150	-	-	-	S	-	-	-	ABC-2 family transporter protein
HFBHIDMB_02074	1.82e-75	ycbP	-	-	S	-	-	-	Protein of unknown function (DUF2512)
HFBHIDMB_02075	4.29e-101	cwlJ	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell wall
HFBHIDMB_02076	3.68e-172	ycbR	-	-	T	-	-	-	vWA found in TerF C terminus
HFBHIDMB_02077	0.0	phoD	3.1.3.1	-	P	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG3540 Phosphodiesterase alkaline phosphatase D
HFBHIDMB_02078	3.12e-38	tatAD	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HFBHIDMB_02079	7.6e-160	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HFBHIDMB_02080	6.93e-154	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HFBHIDMB_02081	4.86e-259	ycbU	-	-	E	-	-	-	Selenocysteine lyase
HFBHIDMB_02082	1.24e-302	lmrB	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	the major facilitator superfamily
HFBHIDMB_02083	1.54e-130	lmrA	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
HFBHIDMB_02084	1.69e-257	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HFBHIDMB_02085	6.64e-146	-	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HFBHIDMB_02086	8.72e-78	-	-	-	S	-	-	-	RDD family
HFBHIDMB_02087	1.01e-254	yccF	-	-	K	ko:K07039	-	ko00000	SEC-C motif
HFBHIDMB_02088	1.98e-209	natK	2.7.13.3	-	T	ko:K11640	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HFBHIDMB_02089	2.3e-161	natR	-	-	T	ko:K02477,ko:K11641	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HFBHIDMB_02090	2.2e-170	natA	3.6.3.7	-	CP	ko:K01990,ko:K09697	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HFBHIDMB_02091	2.19e-119	-	-	-	CP	ko:K09696	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HFBHIDMB_02092	1.39e-113	-	-	-	CP	ko:K09696	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HFBHIDMB_02093	1.13e-220	yccK	-	-	C	-	-	-	Aldo keto reductase
HFBHIDMB_02094	1.35e-241	ycdA	-	-	S	-	-	-	Domain of unknown function (DUF5105)
HFBHIDMB_02095	0.0	ycdB	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HFBHIDMB_02096	0.0	ycdC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HFBHIDMB_02097	1.06e-77	-	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
HFBHIDMB_02098	1.16e-247	rapJ	-	-	S	ko:K06368	-	ko00000,ko01000	Response regulator aspartate phosphatase
HFBHIDMB_02099	6.85e-180	-	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
HFBHIDMB_02100	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
HFBHIDMB_02101	5.58e-221	adcA	-	-	P	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HFBHIDMB_02102	2.32e-169	adcC	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HFBHIDMB_02103	4.63e-173	adcB	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HFBHIDMB_02104	3.44e-237	yceB	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HFBHIDMB_02105	3.75e-141	yceC	3.5.4.33	-	T	ko:K11991	-	ko00000,ko01000,ko03016	proteins involved in stress response, homologs of TerZ and
HFBHIDMB_02106	8.9e-137	yceD	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
HFBHIDMB_02107	4.97e-138	yceE	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
HFBHIDMB_02108	4.1e-176	yceF	-	-	P	ko:K05794	-	ko00000	Protein of unknown function (DUF475)
HFBHIDMB_02109	0.0	yceG	-	-	S	-	-	-	Putative component of 'biosynthetic module'
HFBHIDMB_02110	2.96e-245	yceH	-	-	P	-	-	-	Belongs to the TelA family
HFBHIDMB_02111	1.9e-278	yceI	-	-	P	ko:K08369	-	ko00000,ko02000	Uncharacterised MFS-type transporter YbfB
HFBHIDMB_02112	1.42e-204	-	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
HFBHIDMB_02113	2.79e-60	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HFBHIDMB_02114	8.99e-293	opuAA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
HFBHIDMB_02115	2.1e-186	opuAB	-	-	P	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
HFBHIDMB_02116	1.65e-209	opuAC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
HFBHIDMB_02117	1.69e-277	amhX	-	-	S	ko:K14665	-	ko00000,ko01000,ko01002	amidohydrolase
HFBHIDMB_02118	0.0	ycgA	-	-	S	-	-	-	Membrane
HFBHIDMB_02119	1.25e-127	ycgB	-	-	-	-	-	-	-
HFBHIDMB_02120	0.0	amyE	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	alpha-amylase
HFBHIDMB_02121	1.19e-232	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HFBHIDMB_02122	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HFBHIDMB_02123	0.0	mdr	-	-	EGP	-	-	-	the major facilitator superfamily
HFBHIDMB_02124	3.7e-101	ycgE	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HFBHIDMB_02125	6.42e-147	ycgF	-	-	E	-	-	-	Lysine exporter protein LysE YggA
HFBHIDMB_02126	1.85e-195	yqcI	-	-	S	ko:K09190	-	ko00000	YqcI/YcgG family
HFBHIDMB_02127	0.0	ycgH	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
HFBHIDMB_02128	7.6e-145	ycgI	-	-	S	ko:K09967	-	ko00000	Domain of unknown function (DUF1989)
HFBHIDMB_02129	1.83e-191	nadE	6.3.1.5	-	H	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HFBHIDMB_02130	1.31e-140	tmrB	-	-	S	-	-	-	AAA domain
HFBHIDMB_02131	1.05e-136	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HFBHIDMB_02132	3.05e-185	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
HFBHIDMB_02133	5.4e-226	ycgK	-	-	K	ko:K04761	ko02026,map02026	ko00000,ko00001,ko03000	LysR substrate binding domain
HFBHIDMB_02134	1.29e-230	cah	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	Acetyl xylan esterase (AXE1)
HFBHIDMB_02135	4.49e-186	ycgL	-	-	S	ko:K07074	-	ko00000	Predicted nucleotidyltransferase
HFBHIDMB_02136	3.63e-218	ycgM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
HFBHIDMB_02137	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
HFBHIDMB_02138	2.64e-316	putP	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HFBHIDMB_02139	3.92e-288	ycgP	-	-	QT	-	-	-	COG2508 Regulator of polyketide synthase expression
HFBHIDMB_02140	3.82e-195	ycgQ	-	-	S	ko:K08986	-	ko00000	membrane
HFBHIDMB_02141	3.19e-187	ycgR	-	-	S	ko:K07089	-	ko00000	permeases
HFBHIDMB_02142	1.27e-55	ycgS	-	-	I	-	-	-	alpha/beta hydrolase fold
HFBHIDMB_02143	1.72e-92	ycgS	-	-	I	-	-	-	alpha/beta hydrolase fold
HFBHIDMB_02144	1.58e-240	ycgT	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HFBHIDMB_02145	0.0	nasF	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
HFBHIDMB_02146	1.2e-74	nasE	1.7.1.15	-	P	ko:K00363	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Nitrite reductase
HFBHIDMB_02147	0.0	nasD	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HFBHIDMB_02148	0.0	nasC	-	-	C	ko:K00372	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HFBHIDMB_02149	0.0	nasB	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Assimilatory nitrate reductase (electron transfer subunit)
HFBHIDMB_02150	5.51e-283	nasA	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
HFBHIDMB_02151	2.76e-218	folE2	3.5.4.16	-	S	ko:K09007	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Converts GTP to 7,8-dihydroneopterin triphosphate
HFBHIDMB_02152	2.1e-140	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HFBHIDMB_02153	6.78e-291	yciC	-	-	S	-	-	-	GTPases (G3E family)
HFBHIDMB_02154	2.99e-149	yckA	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
HFBHIDMB_02155	3.09e-186	yckB	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
HFBHIDMB_02157	1.38e-47	yckC	-	-	S	-	-	-	membrane
HFBHIDMB_02158	4.82e-67	yckD	-	-	S	-	-	-	Protein of unknown function (DUF2680)
HFBHIDMB_02159	7.43e-58	-	-	-	K	-	-	-	MarR family
HFBHIDMB_02160	9e-32	-	-	-	-	-	-	-	-
HFBHIDMB_02161	1.16e-154	-	-	-	S	-	-	-	AAA domain
HFBHIDMB_02162	0.0	yckE	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HFBHIDMB_02163	4.78e-91	nin	-	-	S	-	-	-	Competence protein J (ComJ)
HFBHIDMB_02164	3.23e-99	nucA	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
HFBHIDMB_02165	1.52e-267	tlpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HFBHIDMB_02166	1.13e-126	hxlB	5.3.1.27	-	G	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	SIS domain
HFBHIDMB_02167	5.63e-137	hxlA	4.1.2.43	-	G	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	3-hexulose-6-phosphate synthase
HFBHIDMB_02168	6.05e-86	hxlR	-	-	K	-	-	-	transcriptional
HFBHIDMB_02169	0.0	srfAA	-	-	Q	ko:K15654,ko:K15655,ko:K16119	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HFBHIDMB_02171	6.8e-280	srfAB	-	-	Q	ko:K15654,ko:K15655,ko:K16120	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HFBHIDMB_02172	0.0	srfAC	-	-	Q	ko:K15656,ko:K16121	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	COG1020 Non-ribosomal peptide synthetase modules and related proteins
HFBHIDMB_02173	2.71e-178	srfAD	-	-	Q	ko:K15657	ko02024,map02024	ko00000,ko00001,ko01008	thioesterase
HFBHIDMB_02174	2.18e-288	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HFBHIDMB_02175	1.88e-125	-	-	-	S	-	-	-	YcxB-like protein
HFBHIDMB_02176	1.39e-206	ycxC	-	-	EG	-	-	-	EamA-like transporter family
HFBHIDMB_02177	6.85e-123	ycxD	-	-	K	-	-	-	GntR family transcriptional regulator
HFBHIDMB_02178	4.77e-176	ycxD	-	-	K	-	-	-	GntR family transcriptional regulator
HFBHIDMB_02179	4.76e-145	sfp	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
HFBHIDMB_02180	6.13e-148	yczE	-	-	S	ko:K07149	-	ko00000	membrane
HFBHIDMB_02181	7.11e-172	tcyC	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
HFBHIDMB_02182	4.6e-157	tcyB	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
HFBHIDMB_02183	3.03e-188	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HFBHIDMB_02184	5.32e-209	yclA	-	-	K	ko:K21755	-	ko00000,ko03000	LysR substrate binding domain
HFBHIDMB_02185	2.24e-140	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HFBHIDMB_02186	0.0	yclC	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
HFBHIDMB_02187	9.86e-53	-	4.1.1.61	-	S	ko:K21759	ko00627,ko01120,ko01220,map00627,map01120,map01220	ko00000,ko00001,ko01000	response to toxic substance
HFBHIDMB_02188	2.32e-104	yclD	-	-	-	-	-	-	-
HFBHIDMB_02189	5.5e-202	yclE	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Alpha beta hydrolase
HFBHIDMB_02190	0.0	dtpT	-	-	E	ko:K03305	-	ko00000	amino acid peptide transporter
HFBHIDMB_02191	0.0	yclG	-	-	M	-	-	-	Pectate lyase superfamily protein
HFBHIDMB_02193	0.0	gerKA	-	-	EG	ko:K06295,ko:K06307	-	ko00000	Spore germination protein
HFBHIDMB_02194	1.97e-295	gerKC	-	-	S	ko:K06297	-	ko00000	spore germination
HFBHIDMB_02195	1.33e-253	gerKB	-	-	F	ko:K06296	-	ko00000,ko02000	Spore germination protein
HFBHIDMB_02196	5.87e-156	yclH	-	-	P	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HFBHIDMB_02197	6.2e-277	yclI	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease) YclI
HFBHIDMB_02198	4.22e-164	yclJ	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HFBHIDMB_02199	0.0	yclK	-	-	T	-	-	-	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HFBHIDMB_02200	2.18e-97	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
HFBHIDMB_02202	1.58e-05	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
HFBHIDMB_02203	7.93e-06	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
HFBHIDMB_02204	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HFBHIDMB_02205	1.09e-205	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HFBHIDMB_02206	3.16e-209	yclO	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HFBHIDMB_02207	2.29e-175	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HFBHIDMB_02208	5.72e-213	yclQ	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4607 ABC-type enterochelin transport system, periplasmic component
HFBHIDMB_02209	0.0	ycnB	-	-	EGP	-	-	-	the major facilitator superfamily
HFBHIDMB_02210	2.91e-198	ycnC	-	-	K	-	-	-	Transcriptional regulator
HFBHIDMB_02211	8.65e-174	-	1.5.1.39	-	C	ko:K10678,ko:K19286	ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120	ko00000,ko00001,ko01000	Oxidoreductase
HFBHIDMB_02212	1.68e-60	ycnE	-	-	S	-	-	-	Monooxygenase
HFBHIDMB_02213	6.51e-69	yczG	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HFBHIDMB_02214	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HFBHIDMB_02215	9.35e-311	gabT	2.6.1.19, 2.6.1.22	-	E	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HFBHIDMB_02216	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HFBHIDMB_02217	1.67e-190	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	Glucose uptake
HFBHIDMB_02218	5.9e-187	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HFBHIDMB_02219	8.06e-134	ycnI	-	-	S	-	-	-	protein conserved in bacteria
HFBHIDMB_02220	0.0	ycnJ	-	-	P	ko:K14166	-	ko00000,ko02000	protein, homolog of Cu resistance protein CopC
HFBHIDMB_02221	4.98e-137	ycnK	-	-	K	ko:K21601	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
HFBHIDMB_02222	9.44e-75	-	-	-	-	-	-	-	-
HFBHIDMB_02223	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG2213 Phosphotransferase system, mannitol-specific IIBC component
HFBHIDMB_02224	8.3e-95	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
HFBHIDMB_02225	1.21e-265	mtlD	1.1.1.17	-	G	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	COG0246 Mannitol-1-phosphate altronate dehydrogenases
HFBHIDMB_02226	1.01e-256	ycsA	1.1.1.83, 1.1.1.93, 4.1.1.73	-	CE	ko:K07246	ko00630,ko00650,map00630,map00650	ko00000,ko00001,ko01000	Tartrate dehydrogenase
HFBHIDMB_02228	1.25e-96	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HFBHIDMB_02229	3.32e-141	-	-	-	Q	-	-	-	COG0412 Dienelactone hydrolase and related enzymes
HFBHIDMB_02230	1.89e-87	ycsD	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
HFBHIDMB_02232	1.9e-177	ycsE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
HFBHIDMB_02233	3.14e-180	ycsF	-	-	S	ko:K07160	-	ko00000	Belongs to the UPF0271 (lamB) family
HFBHIDMB_02234	1.32e-271	ycsG	-	-	P	-	-	-	COG1914 Mn2 and Fe2 transporters of the NRAMP family
HFBHIDMB_02235	2.01e-189	ycsI	-	-	S	-	-	-	Belongs to the D-glutamate cyclase family
HFBHIDMB_02236	2.05e-172	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
HFBHIDMB_02237	1.91e-236	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
HFBHIDMB_02238	3.8e-171	kipR	-	-	K	-	-	-	Transcriptional regulator
HFBHIDMB_02239	1.91e-150	ycsK	-	-	E	-	-	-	anatomical structure formation involved in morphogenesis
HFBHIDMB_02241	8.97e-65	yczJ	-	-	S	-	-	-	biosynthesis
HFBHIDMB_02242	0.0	pbpC	3.4.16.4	-	M	ko:K02545,ko:K21467	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	Penicillin-binding Protein
HFBHIDMB_02243	2.57e-221	ycsN	-	-	S	-	-	-	Oxidoreductase
HFBHIDMB_02244	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	transcriptional regulator, MtlR
HFBHIDMB_02245	0.0	ydaB	-	-	IQ	-	-	-	acyl-CoA ligase
HFBHIDMB_02246	6.78e-126	ydaC	-	-	Q	-	-	-	Methyltransferase domain
HFBHIDMB_02247	3.74e-207	ydaD	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HFBHIDMB_02248	2.36e-126	ydaE	5.3.1.15	-	S	ko:K09988	ko00040,map00040	ko00000,ko00001,ko01000	Cupin 2, conserved barrel domain protein
HFBHIDMB_02249	2.58e-131	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HFBHIDMB_02250	5.24e-101	ydaG	-	-	S	-	-	-	general stress protein
HFBHIDMB_02251	1.87e-178	amj	-	-	U	-	-	-	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HFBHIDMB_02252	3.12e-61	ydzA	-	-	EGP	-	-	-	Domain of unknown function (DUF3817)
HFBHIDMB_02253	3.95e-98	lrpC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
HFBHIDMB_02254	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HFBHIDMB_02255	9.49e-262	ydaJ	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HFBHIDMB_02256	6.34e-193	ydaK	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
HFBHIDMB_02257	0.0	ydaL	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2334)
HFBHIDMB_02258	1.12e-303	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
HFBHIDMB_02259	6.94e-143	ydaN	-	-	S	-	-	-	Bacterial cellulose synthase subunit
HFBHIDMB_02260	1.45e-307	ydaN	-	-	S	-	-	-	Bacterial cellulose synthase subunit
HFBHIDMB_02261	0.0	ydaO	-	-	E	-	-	-	amino acid
HFBHIDMB_02262	1.79e-101	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
HFBHIDMB_02263	0.0	ydaP	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HFBHIDMB_02265	1.84e-34	-	-	-	-	-	-	-	-
HFBHIDMB_02266	2.18e-90	sdpB	-	-	S	-	-	-	Protein conserved in bacteria
HFBHIDMB_02268	2.14e-53	-	-	-	-	-	-	-	-
HFBHIDMB_02269	1.59e-285	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HFBHIDMB_02270	1.67e-42	ydaS	-	-	S	-	-	-	membrane
HFBHIDMB_02271	2.25e-100	ydaT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
HFBHIDMB_02272	2.49e-189	ydbA	-	-	P	-	-	-	EcsC protein family
HFBHIDMB_02273	1.75e-10	gsiB	-	-	S	ko:K06884	-	ko00000	general stress protein
HFBHIDMB_02274	1.25e-74	ydbB	-	-	G	-	-	-	Cupin domain
HFBHIDMB_02275	3.53e-80	ydbC	-	-	S	-	-	-	Domain of unknown function (DUF4937
HFBHIDMB_02276	2.24e-197	ydbD	-	-	P	ko:K07217	-	ko00000	Catalase
HFBHIDMB_02277	3.66e-253	dctB	-	-	G	-	-	-	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HFBHIDMB_02278	1.5e-31	dctS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
HFBHIDMB_02279	0.0	dctS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
HFBHIDMB_02280	3.39e-155	dctR	-	-	T	ko:K02475,ko:K11692	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
HFBHIDMB_02281	1.27e-289	dctA	-	-	U	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HFBHIDMB_02282	1.32e-230	ydbI	-	-	S	-	-	-	AI-2E family transporter
HFBHIDMB_02283	2.28e-219	ydbJ	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFBHIDMB_02284	7.34e-160	ydbK	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HFBHIDMB_02285	9.32e-70	ydbL	-	-	-	-	-	-	-
HFBHIDMB_02286	1.83e-280	ydbM	-	-	I	-	-	-	acyl-CoA dehydrogenase
HFBHIDMB_02287	1.49e-26	-	-	-	S	-	-	-	Fur-regulated basic protein B
HFBHIDMB_02289	1.91e-202	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HFBHIDMB_02290	4.19e-75	ydbP	-	-	CO	-	-	-	Thioredoxin
HFBHIDMB_02291	3.07e-258	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HFBHIDMB_02292	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HFBHIDMB_02293	0.0	cshA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HFBHIDMB_02294	2.12e-107	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
HFBHIDMB_02295	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Membrane
HFBHIDMB_02296	2.53e-139	ydcA	-	-	S	-	-	-	membrane protein (homolog of Drosophila rhomboid)
HFBHIDMB_02297	1.95e-78	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HFBHIDMB_02298	4.66e-234	ydcC	-	-	M	-	-	-	COG2834 Outer membrane lipoprotein-sorting protein
HFBHIDMB_02299	5.29e-284	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HFBHIDMB_02300	9.49e-57	ndoAI	-	-	K	ko:K07723	-	ko00000,ko02048,ko03000	transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HFBHIDMB_02301	4.34e-75	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HFBHIDMB_02302	8.58e-184	rsbR	-	-	T	ko:K17763	-	ko00000,ko03021	Positive regulator of sigma-B
HFBHIDMB_02303	7.34e-74	rsbS	-	-	T	ko:K17762	-	ko00000,ko03021	antagonist
HFBHIDMB_02304	8.56e-90	rsbT	2.7.11.1	-	T	ko:K17752	-	ko00000,ko01000,ko01001,ko03021	COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HFBHIDMB_02305	1.31e-243	rsbU	3.1.3.3	-	KT	ko:K07315	-	ko00000,ko01000,ko03021	phosphatase
HFBHIDMB_02306	1.97e-70	rsbV	-	-	T	ko:K04749	-	ko00000,ko03021	Belongs to the anti-sigma-factor antagonist family
HFBHIDMB_02307	2.48e-111	rsbW	2.7.11.1	-	F	ko:K04757	-	ko00000,ko01000,ko01001,ko03021	Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HFBHIDMB_02308	1.55e-178	sigB	-	-	K	ko:K03090	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HFBHIDMB_02309	4.38e-140	rsbX	3.1.3.3	-	KT	ko:K05518	-	ko00000,ko01000,ko03021	Sigma factor PP2C-like phosphatases
HFBHIDMB_02312	1.32e-106	ydcG	-	-	S	-	-	-	EVE domain
HFBHIDMB_02313	1.04e-99	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HFBHIDMB_02314	0.0	tex	-	-	K	ko:K06959	-	ko00000	COG2183 Transcriptional accessory protein
HFBHIDMB_02315	1.53e-107	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HFBHIDMB_02323	2.97e-268	ydcL	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HFBHIDMB_02324	1.65e-118	-	-	-	E	-	-	-	IrrE N-terminal-like domain
HFBHIDMB_02325	1.91e-81	-	-	-	K	-	-	-	Transcriptional
HFBHIDMB_02326	8.96e-24	-	-	-	-	-	-	-	-
HFBHIDMB_02327	1.35e-55	-	-	-	-	-	-	-	-
HFBHIDMB_02329	1.84e-83	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF961)
HFBHIDMB_02330	0.0	ydcQ	-	-	D	ko:K03466	-	ko00000,ko03036	Ftsk spoiiie family protein
HFBHIDMB_02331	1.63e-257	nicK	-	-	L	ko:K07467	-	ko00000	Replication initiation factor
HFBHIDMB_02332	3.97e-49	-	-	-	-	-	-	-	-
HFBHIDMB_02334	8.25e-63	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
HFBHIDMB_02335	2.33e-57	-	-	-	-	-	-	-	-
HFBHIDMB_02336	1.51e-49	-	-	-	S	ko:K21493	-	ko00000,ko01000,ko02048	LXG domain of WXG superfamily
HFBHIDMB_02337	1.68e-82	-	-	-	M	-	-	-	nucleic acid phosphodiester bond hydrolysis
HFBHIDMB_02339	4.75e-245	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
HFBHIDMB_02340	4.22e-41	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
HFBHIDMB_02341	1.45e-102	ydeB	-	-	K	ko:K07736	-	ko00000,ko03000	Transcription factor
HFBHIDMB_02342	6.72e-41	ydzE	-	-	EG	-	-	-	spore germination
HFBHIDMB_02343	1.08e-209	-	-	-	K	-	-	-	AraC-like ligand binding domain
HFBHIDMB_02344	3.37e-222	ydeD	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HFBHIDMB_02345	9.2e-210	ydeE	-	-	K	ko:K13653	-	ko00000,ko03000	AraC family transcriptional regulator
HFBHIDMB_02346	0.0	-	-	-	K	-	-	-	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HFBHIDMB_02347	1.27e-275	ydeG	-	-	EGP	-	-	-	Major facilitator superfamily
HFBHIDMB_02348	3.21e-70	ydeH	-	-	-	-	-	-	-
HFBHIDMB_02349	5.52e-133	ydeI	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
HFBHIDMB_02350	2.67e-144	-	-	-	-	-	-	-	-
HFBHIDMB_02351	1.28e-194	ydeK	-	-	EG	-	-	-	-transporter
HFBHIDMB_02352	0.0	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HFBHIDMB_02353	3.68e-97	ydeM1	-	-	I	-	-	-	N-terminal half of MaoC dehydratase
HFBHIDMB_02354	1.56e-131	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
HFBHIDMB_02355	1.02e-72	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HFBHIDMB_02356	6.56e-194	ydeO	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HFBHIDMB_02357	3e-75	arsR	-	-	K	ko:K03892,ko:K22043	-	ko00000,ko03000	transcriptional
HFBHIDMB_02358	7.13e-294	arsB	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HFBHIDMB_02359	5.44e-189	-	-	-	J	-	-	-	GNAT acetyltransferase
HFBHIDMB_02360	1.45e-205	-	-	-	EG	-	-	-	EamA-like transporter family
HFBHIDMB_02361	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HFBHIDMB_02362	1.54e-232	-	4.1.1.86	-	E	ko:K13745	ko00260,ko01120,map00260,map01120	ko00000,ko00001,ko01000	Pyridoxal-dependent decarboxylase conserved domain
HFBHIDMB_02363	4.04e-149	ydfE	-	-	S	-	-	-	Flavin reductase like domain
HFBHIDMB_02364	1.23e-157	ydfF	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HFBHIDMB_02365	3.92e-104	-	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HFBHIDMB_02366	2.77e-251	ydfH	2.7.13.3	-	T	ko:K11623	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HFBHIDMB_02367	2.3e-142	ydfI	-	-	K	ko:K11624	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HFBHIDMB_02368	0.0	ydfJ	-	-	S	ko:K06994,ko:K11625	ko02020,map02020	ko00000,ko00001	drug exporters of the RND superfamily
HFBHIDMB_02369	8.25e-218	-	-	-	S	-	-	-	Alpha/beta hydrolase family
HFBHIDMB_02370	3.77e-149	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HFBHIDMB_02371	3.54e-188	-	-	-	K	-	-	-	Bacterial transcription activator, effector binding domain
HFBHIDMB_02372	5.22e-199	ydfM	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HFBHIDMB_02373	4.7e-143	ydfN	-	-	C	ko:K15976	-	ko00000,ko01000	nitroreductase
HFBHIDMB_02374	1.11e-237	ydfO	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
HFBHIDMB_02375	8.02e-84	ydfP	-	-	S	ko:K15977	-	ko00000	DoxX
HFBHIDMB_02376	3.78e-74	ydfQ	-	-	CO	-	-	-	Thioredoxin
HFBHIDMB_02377	2.4e-21	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
HFBHIDMB_02378	5.33e-39	-	-	-	-	-	-	-	-
HFBHIDMB_02380	6.08e-153	ydfR	-	-	S	-	-	-	Protein of unknown function (DUF421)
HFBHIDMB_02381	4.44e-160	ydfS	-	-	S	-	-	-	Protein of unknown function (DUF421)
HFBHIDMB_02382	3.13e-99	cotP	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HFBHIDMB_02383	2.74e-50	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
HFBHIDMB_02384	2.19e-56	ydgB	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
HFBHIDMB_02385	2.85e-126	ydgC	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HFBHIDMB_02386	5.76e-70	-	-	-	S	-	-	-	DoxX-like family
HFBHIDMB_02387	1.82e-109	yycN	-	-	K	-	-	-	Acetyltransferase
HFBHIDMB_02388	0.0	expZ	-	-	S	ko:K18231	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ABC transporter
HFBHIDMB_02389	0.0	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
HFBHIDMB_02390	1.16e-107	-	-	-	S	-	-	-	DinB family
HFBHIDMB_02391	3.87e-102	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HFBHIDMB_02392	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	drug exporters of the RND superfamily
HFBHIDMB_02393	6.42e-147	ydgI	-	-	C	-	-	-	nitroreductase
HFBHIDMB_02394	3.29e-90	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HFBHIDMB_02395	9.89e-266	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
HFBHIDMB_02396	1.02e-154	ydhB	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HFBHIDMB_02397	4.31e-157	ydhC	-	-	K	-	-	-	FCD
HFBHIDMB_02398	5.16e-309	ydhD	-	-	M	-	-	-	Glycosyl hydrolase
HFBHIDMB_02399	3.91e-289	ydhE	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HFBHIDMB_02400	1.43e-161	-	-	-	-	-	-	-	-
HFBHIDMB_02401	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
HFBHIDMB_02402	2.74e-88	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
HFBHIDMB_02404	7.65e-108	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HFBHIDMB_02405	1.56e-230	ydhJ	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HFBHIDMB_02406	3.84e-126	ydhK	-	-	M	-	-	-	Protein of unknown function (DUF1541)
HFBHIDMB_02407	2.56e-254	ydhL	-	-	EGP	ko:K18567	-	ko00000,ko02000	COG2814 Arabinose efflux permease
HFBHIDMB_02408	1.88e-63	ydhM	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HFBHIDMB_02409	3.39e-67	ydhN3	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HFBHIDMB_02410	3.76e-304	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFBHIDMB_02411	0.0	ydhP	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HFBHIDMB_02412	7.75e-171	ydhQ	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
HFBHIDMB_02413	1.65e-212	gmuE	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	COG1940 Transcriptional regulator sugar kinase
HFBHIDMB_02414	3.44e-238	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HFBHIDMB_02415	2.64e-268	ydhT1	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 26 family
HFBHIDMB_02416	4.79e-100	ydhU	-	-	P	ko:K07217	-	ko00000	Catalase
HFBHIDMB_02417	7.94e-22	ydhU	-	-	P	ko:K07217	-	ko00000	Manganese containing catalase
HFBHIDMB_02420	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
HFBHIDMB_02421	1.46e-117	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HFBHIDMB_02422	2.14e-148	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HFBHIDMB_02423	5.48e-31	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HFBHIDMB_02424	8.73e-162	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HFBHIDMB_02425	3.2e-37	ydiK	-	-	S	-	-	-	Domain of unknown function (DUF4305)
HFBHIDMB_02426	3e-167	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HFBHIDMB_02427	2.14e-58	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HFBHIDMB_02428	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HFBHIDMB_02429	1.56e-181	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HFBHIDMB_02430	1.35e-61	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
HFBHIDMB_02431	2.92e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF4064)
HFBHIDMB_02432	4.37e-84	-	-	-	-	-	-	-	-
HFBHIDMB_02434	1.01e-21	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HFBHIDMB_02435	3e-05	-	-	-	K	-	-	-	Helix-turn-helix domain
HFBHIDMB_02436	9.71e-48	-	-	-	-	-	-	-	-
HFBHIDMB_02437	5.93e-93	-	-	-	K	ko:K07741	-	ko00000	BRO family, N-terminal domain
HFBHIDMB_02438	4.65e-112	-	-	-	-	-	-	-	-
HFBHIDMB_02443	1.09e-192	yqaJ	-	-	L	-	-	-	YqaJ-like viral recombinase domain
HFBHIDMB_02444	2.54e-171	recT	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
HFBHIDMB_02445	1.23e-43	yqaL	-	-	L	-	-	-	DnaD domain protein
HFBHIDMB_02446	5.09e-164	yqaM	-	-	L	-	-	-	IstB-like ATP binding protein
HFBHIDMB_02448	6.29e-13	-	-	-	S	-	-	-	YopX protein
HFBHIDMB_02449	1.83e-70	-	-	-	S	-	-	-	Protein of unknown function (DUF1064)
HFBHIDMB_02451	2.97e-26	yqaO	-	-	S	-	-	-	Phage-like element PBSX protein XtrA
HFBHIDMB_02457	4.33e-90	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HFBHIDMB_02459	8.99e-20	-	-	-	K	-	-	-	Transcriptional regulator
HFBHIDMB_02462	7.14e-113	yqaS	-	-	L	-	-	-	DNA packaging
HFBHIDMB_02463	5.15e-233	-	-	-	S	-	-	-	Terminase-like family
HFBHIDMB_02464	1.61e-192	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
HFBHIDMB_02466	4.59e-77	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
HFBHIDMB_02467	8.27e-157	-	-	-	S	-	-	-	Phage capsid family
HFBHIDMB_02469	1.04e-39	-	-	-	S	-	-	-	Phage Mu protein F like protein
HFBHIDMB_02471	2.44e-61	-	-	-	-	-	-	-	-
HFBHIDMB_02473	6.84e-40	-	-	-	-	-	-	-	-
HFBHIDMB_02474	4.59e-128	-	-	-	S	-	-	-	Protein of unknown function (DUF3383)
HFBHIDMB_02475	8.46e-46	-	-	-	-	-	-	-	-
HFBHIDMB_02476	1.59e-10	-	-	-	-	-	-	-	-
HFBHIDMB_02477	2.41e-161	-	-	-	N	-	-	-	phage tail tape measure protein
HFBHIDMB_02478	6.22e-47	-	-	-	M	-	-	-	LysM domain
HFBHIDMB_02479	1.13e-41	-	-	-	-	-	-	-	-
HFBHIDMB_02480	3.69e-111	-	-	-	-	-	-	-	-
HFBHIDMB_02482	6.43e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF2634)
HFBHIDMB_02483	1.84e-130	-	-	-	S	-	-	-	homolog of phage Mu protein gp47
HFBHIDMB_02484	1.22e-78	-	-	-	-	-	-	-	-
HFBHIDMB_02485	2.68e-22	-	-	-	-	-	-	-	-
HFBHIDMB_02486	4.39e-12	-	-	-	-	-	-	-	-
HFBHIDMB_02488	4.24e-122	-	3.1.4.46, 5.4.2.11	-	C	ko:K01126,ko:K01834	ko00010,ko00260,ko00564,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00564,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	glycerophosphoryl diester phosphodiesterase
HFBHIDMB_02489	7.72e-37	xhlA	-	-	S	-	-	-	Haemolysin XhlA
HFBHIDMB_02490	1.25e-38	xhlB	-	-	S	-	-	-	SPP1 phage holin
HFBHIDMB_02491	2.05e-158	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
HFBHIDMB_02492	4.72e-51	-	-	-	S	-	-	-	protein domain associated with
HFBHIDMB_02494	7.9e-37	-	-	-	K	-	-	-	Helix-turn-helix domain
HFBHIDMB_02495	6.6e-49	-	-	-	-	-	-	-	-
HFBHIDMB_02497	2.91e-40	-	-	-	U	ko:K03071	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03110	Preprotein translocase subunit SecB
HFBHIDMB_02498	5.41e-20	-	-	-	-	-	-	-	-
HFBHIDMB_02500	1.93e-53	-	-	-	-	-	-	-	-
HFBHIDMB_02501	2.47e-293	-	-	-	S	-	-	-	Bacterial EndoU nuclease
HFBHIDMB_02504	4.31e-82	yozB	-	-	S	ko:K08976	-	ko00000	Membrane
HFBHIDMB_02505	1.19e-30	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HFBHIDMB_02506	0.0	gutR	-	-	K	ko:K16247	-	ko00000,ko03000	NB-ARC domain
HFBHIDMB_02507	1.51e-258	gutB	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
HFBHIDMB_02508	0.0	gutP	-	-	G	ko:K03292,ko:K16248	-	ko00000,ko02000	MFS/sugar transport protein
HFBHIDMB_02509	1.73e-220	ydjE	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
HFBHIDMB_02510	3.1e-147	pspA	-	-	KT	ko:K03969	-	ko00000	Phage shock protein A
HFBHIDMB_02511	4.25e-227	ydjG	-	-	L	-	-	-	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HFBHIDMB_02512	8.23e-170	ydjH	-	-	S	ko:K06872	-	ko00000	COG1512 Beta-propeller domains of methanol dehydrogenase type
HFBHIDMB_02513	4.21e-202	ydjI	-	-	S	-	-	-	virion core protein (lumpy skin disease virus)
HFBHIDMB_02514	5.58e-248	-	-	-	S	-	-	-	Ion transport 2 domain protein
HFBHIDMB_02515	0.0	iolT	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HFBHIDMB_02516	3.5e-249	ydjL	1.1.1.264, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00098	ko00650,map00650	ko00000,ko00001,ko01000	Dehydrogenase
HFBHIDMB_02517	1.79e-84	ydjM	-	-	M	-	-	-	Lytic transglycolase
HFBHIDMB_02518	2.81e-208	ydjN	-	-	U	-	-	-	Involved in the tonB-independent uptake of proteins
HFBHIDMB_02520	8.2e-48	ydjO	-	-	S	-	-	-	Cold-inducible protein YdjO
HFBHIDMB_02521	1.78e-202	-	-	-	I	-	-	-	Alpha/beta hydrolase family
HFBHIDMB_02522	1.54e-225	yeaA	-	-	S	-	-	-	Protein of unknown function (DUF4003)
HFBHIDMB_02523	0.0	cotA	1.16.3.3	-	Q	ko:K06324	-	ko00000,ko01000	multicopper oxidases
HFBHIDMB_02524	0.0	gabP	-	-	E	ko:K11735	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
HFBHIDMB_02525	1.76e-198	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HFBHIDMB_02526	3.25e-225	yeaC	-	-	S	ko:K03924	-	ko00000,ko01000	COG0714 MoxR-like ATPases
HFBHIDMB_02527	5.31e-284	yeaD	-	-	S	-	-	-	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
HFBHIDMB_02528	0.0	yebA	-	-	E	-	-	-	COG1305 Transglutaminase-like enzymes
HFBHIDMB_02529	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HFBHIDMB_02530	1.05e-109	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HFBHIDMB_02531	3.15e-312	-	-	-	S	-	-	-	Domain of unknown function (DUF4179)
HFBHIDMB_02532	1.2e-283	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HFBHIDMB_02533	1.44e-165	yebC	-	-	M	-	-	-	Membrane
HFBHIDMB_02535	2.66e-120	yebE	-	-	S	-	-	-	UPF0316 protein
HFBHIDMB_02536	3.13e-38	yebG	-	-	S	-	-	-	NETI protein
HFBHIDMB_02537	2.28e-108	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HFBHIDMB_02538	9.39e-278	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HFBHIDMB_02539	6.85e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HFBHIDMB_02540	1.06e-170	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HFBHIDMB_02541	3.79e-52	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HFBHIDMB_02542	1.15e-167	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HFBHIDMB_02543	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HFBHIDMB_02544	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HFBHIDMB_02545	9.88e-240	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HFBHIDMB_02546	7.3e-137	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HFBHIDMB_02547	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HFBHIDMB_02548	1.63e-297	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HFBHIDMB_02549	1.06e-95	-	-	-	K	-	-	-	helix_turn_helix ASNC type
HFBHIDMB_02550	1.67e-291	-	-	-	E	ko:K16263	-	ko00000,ko02000	Amino acid permease
HFBHIDMB_02551	3.45e-37	-	-	-	S	-	-	-	Protein of unknown function (DUF2892)
HFBHIDMB_02552	0.0	yerA	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	adenine deaminase
HFBHIDMB_02553	9.58e-244	yerB	-	-	S	-	-	-	Protein of unknown function (DUF3048) C-terminal domain
HFBHIDMB_02554	7.62e-68	yerC	-	-	S	-	-	-	protein conserved in bacteria
HFBHIDMB_02555	0.0	yerD	1.4.7.1	-	E	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	ko00000,ko00001,ko01000	Belongs to the glutamate synthase family
HFBHIDMB_02557	9.04e-161	pcrB	-	-	I	ko:K07094	-	ko00000,ko01000	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HFBHIDMB_02558	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HFBHIDMB_02559	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HFBHIDMB_02560	1.77e-281	camS	-	-	S	-	-	-	COG4851 Protein involved in sex pheromone biosynthesis
HFBHIDMB_02561	9.99e-250	yerI	-	-	S	-	-	-	homoserine kinase type II (protein kinase fold)
HFBHIDMB_02562	2.29e-160	sapB	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
HFBHIDMB_02563	0.0	putP	-	-	E	ko:K03307,ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HFBHIDMB_02564	7.37e-61	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HFBHIDMB_02566	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HFBHIDMB_02567	4.91e-189	yerO	-	-	K	-	-	-	Transcriptional regulator
HFBHIDMB_02568	0.0	swrC	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HFBHIDMB_02569	1.8e-218	dagK	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HFBHIDMB_02570	0.0	rlmCD	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HFBHIDMB_02571	8.51e-06	-	-	-	-	-	-	-	-
HFBHIDMB_02572	2.52e-102	-	-	-	S	-	-	-	Protein of unknown function, DUF600
HFBHIDMB_02573	2.39e-68	-	-	-	S	-	-	-	Protein of unknown function, DUF600
HFBHIDMB_02574	2.48e-66	-	-	-	S	-	-	-	Protein of unknown function, DUF600
HFBHIDMB_02575	0.0	-	-	-	L	-	-	-	nucleic acid phosphodiester bond hydrolysis
HFBHIDMB_02577	8.06e-126	-	-	-	L	-	-	-	endonuclease activity
HFBHIDMB_02578	4.98e-15	-	-	-	S	-	-	-	Lysozyme inhibitor LprI
HFBHIDMB_02579	2.57e-273	rapH	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Tetratricopeptide repeat
HFBHIDMB_02581	6.29e-162	yeeN	-	-	K	-	-	-	transcriptional regulatory protein
HFBHIDMB_02583	2.44e-130	dhaR3	-	-	K	ko:K16137	-	ko00000,ko03000	Transcriptional regulator
HFBHIDMB_02584	4.95e-107	yesE	-	-	S	ko:K06893	-	ko00000	SnoaL-like domain
HFBHIDMB_02585	5.83e-194	yesF	-	-	GM	-	-	-	NAD(P)H-binding
HFBHIDMB_02586	3.8e-60	cotJA	-	-	S	ko:K06332	-	ko00000	Spore coat associated protein JA (CotJA)
HFBHIDMB_02587	2.31e-61	cotJB	-	-	S	ko:K06333	-	ko00000	CotJB protein
HFBHIDMB_02588	1.04e-133	cotJC	-	-	P	ko:K06334	-	ko00000	Spore Coat
HFBHIDMB_02589	9.78e-130	yesJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HFBHIDMB_02591	1.95e-132	yesL	-	-	S	-	-	-	Protein of unknown function, DUF624
HFBHIDMB_02592	0.0	yesM	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HFBHIDMB_02593	2.93e-259	-	-	-	K	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
HFBHIDMB_02594	4.13e-314	yesO	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HFBHIDMB_02595	4.76e-217	yesP	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HFBHIDMB_02596	5.33e-212	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HFBHIDMB_02597	3.26e-253	-	3.2.1.172	GH105	S	ko:K15532	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
HFBHIDMB_02598	0.0	yesS	-	-	K	-	-	-	Transcriptional regulator
HFBHIDMB_02599	1.19e-169	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HFBHIDMB_02600	1.25e-163	yesU	-	-	S	-	-	-	Domain of unknown function (DUF1961)
HFBHIDMB_02601	4.02e-145	-	-	-	S	-	-	-	Protein of unknown function, DUF624
HFBHIDMB_02602	0.0	-	4.2.2.23, 4.2.2.24	PL11	E	ko:K18197,ko:K18198	-	ko00000,ko01000	cell wall organization
HFBHIDMB_02603	0.0	yesX	4.2.2.23, 4.2.2.24	PL11	E	ko:K18197,ko:K18198	-	ko00000,ko01000	cell wall organization
HFBHIDMB_02604	7.51e-159	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HFBHIDMB_02605	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase activity
HFBHIDMB_02606	0.0	yetA	-	-	-	-	-	-	-
HFBHIDMB_02607	0.0	lplA	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HFBHIDMB_02608	2.78e-225	lplB	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4209 ABC-type polysaccharide transport system, permease component
HFBHIDMB_02609	7.85e-209	-	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HFBHIDMB_02610	0.0	-	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
HFBHIDMB_02611	1.81e-157	yetF	-	-	S	-	-	-	membrane
HFBHIDMB_02612	4.67e-73	yetG	1.14.99.48	-	S	ko:K07145	ko00860,ko01110,map00860,map01110	ko00000,ko00001,ko01000	Antibiotic biosynthesis monooxygenase
HFBHIDMB_02613	2.47e-85	yetH	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HFBHIDMB_02614	1.75e-44	-	-	-	-	-	-	-	-
HFBHIDMB_02615	7.23e-184	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HFBHIDMB_02616	4.46e-27	yezD	-	-	S	-	-	-	Uncharacterized small protein (DUF2292)
HFBHIDMB_02617	2.55e-135	yetJ	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HFBHIDMB_02618	1.42e-200	-	-	-	EG	-	-	-	EamA-like transporter family
HFBHIDMB_02619	1.86e-114	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HFBHIDMB_02620	2.43e-263	yetM	-	-	CH	-	-	-	FAD binding domain
HFBHIDMB_02621	2.55e-65	-	-	-	-	-	-	-	-
HFBHIDMB_02622	2.02e-250	yetN	-	-	S	-	-	-	Protein of unknown function (DUF3900)
HFBHIDMB_02623	0.0	cypD	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
HFBHIDMB_02624	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
HFBHIDMB_02625	9.83e-187	yfnH	2.7.7.33	-	JM	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	ko00000,ko00001,ko01000	Nucleotidyl transferase
HFBHIDMB_02626	1.37e-219	yfnG	4.2.1.45, 4.2.1.46	-	M	ko:K01709,ko:K01710	ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	dehydratase
HFBHIDMB_02627	3.99e-231	yfnF	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
HFBHIDMB_02628	2.44e-286	yfnE	-	-	S	-	-	-	Glycosyltransferase like family 2
HFBHIDMB_02629	3.88e-242	yfnD	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
HFBHIDMB_02630	6.21e-268	fsr	-	-	P	ko:K08223	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HFBHIDMB_02631	4.31e-167	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HFBHIDMB_02632	2.4e-312	yfnA	-	-	E	ko:K03294	-	ko00000	amino acid
HFBHIDMB_02633	0.0	yfmT	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HFBHIDMB_02634	5.14e-161	yfmS	-	-	NT	-	-	-	chemotaxis protein
HFBHIDMB_02635	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HFBHIDMB_02636	1.31e-98	yfmQ	-	-	S	-	-	-	Uncharacterised protein from bacillus cereus group
HFBHIDMB_02637	3.54e-90	yfmP	-	-	K	ko:K21902	-	ko00000,ko03000	transcriptional
HFBHIDMB_02638	7.24e-265	yfmO	-	-	EGP	ko:K08221	-	ko00000,ko02000	Major facilitator superfamily
HFBHIDMB_02639	5.23e-35	-	-	-	-	-	-	-	-
HFBHIDMB_02640	0.0	yheS_1	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HFBHIDMB_02641	4.19e-263	yfmL	-	-	L	-	-	-	COG0513 Superfamily II DNA and RNA helicases
HFBHIDMB_02642	1.53e-97	yfmK	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	acetyltransferase
HFBHIDMB_02643	9.5e-239	yfmJ	-	-	S	ko:K07119	-	ko00000	N-terminal domain of oxidoreductase
HFBHIDMB_02644	1.4e-192	fhuC	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HFBHIDMB_02645	2.01e-221	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HFBHIDMB_02646	8.17e-221	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HFBHIDMB_02647	1.17e-220	yfmC	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
HFBHIDMB_02648	1.06e-31	-	-	-	S	-	-	-	Protein of unknown function (DUF3212)
HFBHIDMB_02649	1.71e-76	yflT	-	-	S	-	-	-	Heat induced stress protein YflT
HFBHIDMB_02650	2.45e-307	pel	4.2.2.2	-	G	ko:K01728	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectate lyase
HFBHIDMB_02651	0.0	yflS	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HFBHIDMB_02652	0.0	citS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
HFBHIDMB_02653	2.2e-151	citT	-	-	T	ko:K11638	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HFBHIDMB_02654	1.62e-229	yflP	-	-	S	-	-	-	Tripartite tricarboxylate transporter family receptor
HFBHIDMB_02655	5.35e-288	citM	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
HFBHIDMB_02656	1.7e-192	yflN	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
HFBHIDMB_02657	5.59e-275	nos	1.14.14.47	-	C	ko:K00491	ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HFBHIDMB_02658	2.97e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HFBHIDMB_02659	3.42e-157	yflK	-	-	S	-	-	-	protein conserved in bacteria
HFBHIDMB_02660	3.16e-25	yflJ	-	-	S	-	-	-	Protein of unknown function (DUF2639)
HFBHIDMB_02661	6.9e-27	yflI	-	-	-	-	-	-	-
HFBHIDMB_02662	1.48e-65	yflH	-	-	S	-	-	-	Protein of unknown function (DUF3243)
HFBHIDMB_02663	1.14e-178	yflG	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
HFBHIDMB_02664	0.0	nagE	2.7.1.193, 2.7.1.199	-	G	ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HFBHIDMB_02665	0.0	yflE	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
HFBHIDMB_02666	1.89e-87	ydhN1	-	-	S	-	-	-	Domain of unknown function (DUF1992)
HFBHIDMB_02667	0.0	yflA	-	-	E	ko:K03310	-	ko00000	Sodium alanine symporter
HFBHIDMB_02668	1.36e-32	yfkQ	-	-	EG	ko:K06295,ko:K06307	-	ko00000	Spore germination protein
HFBHIDMB_02669	0.0	treP	2.7.1.201	-	G	ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HFBHIDMB_02670	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
HFBHIDMB_02671	1.24e-172	treR	-	-	K	ko:K03486	-	ko00000,ko03000	transcriptional
HFBHIDMB_02672	6.16e-160	frp	-	-	C	-	-	-	nitroreductase
HFBHIDMB_02673	0.0	yfkN	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HFBHIDMB_02674	2.23e-113	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
HFBHIDMB_02675	6.21e-266	ydiN3	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HFBHIDMB_02676	5.99e-41	yfkK	-	-	S	-	-	-	Belongs to the UPF0435 family
HFBHIDMB_02677	9.78e-107	yfkJ	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HFBHIDMB_02678	1.03e-66	yfkI	-	-	S	-	-	-	gas vesicle protein
HFBHIDMB_02679	9.64e-184	yihY	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HFBHIDMB_02680	1.64e-12	-	-	-	-	-	-	-	-
HFBHIDMB_02681	1.9e-278	yfkF	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HFBHIDMB_02682	1.34e-235	cax	-	-	P	ko:K07300	-	ko00000,ko02000	COG0387 Ca2 H antiporter
HFBHIDMB_02683	3.69e-189	yfkD	-	-	S	-	-	-	YfkD-like protein
HFBHIDMB_02684	4.44e-191	yfkC	-	-	M	-	-	-	Mechanosensitive ion channel
HFBHIDMB_02685	1.19e-281	yfkA	-	-	S	-	-	-	YfkB-like domain
HFBHIDMB_02686	3.26e-36	yfjT	-	-	-	-	-	-	-
HFBHIDMB_02687	4.19e-197	pdaA	-	-	G	ko:K01567	-	ko00000,ko01000	deacetylase
HFBHIDMB_02688	4.43e-190	yfjR	-	-	I	-	-	-	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HFBHIDMB_02689	7.8e-237	corA	-	-	P	ko:K03284	-	ko00000,ko02000	Mediates influx of magnesium ions
HFBHIDMB_02690	7.91e-214	yfjP	3.2.2.21	-	L	ko:K01247	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HFBHIDMB_02691	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HFBHIDMB_02692	3.04e-59	-	-	-	S	-	-	-	YfzA-like protein
HFBHIDMB_02693	9.53e-241	yfjN	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HFBHIDMB_02694	2.53e-106	yfjM	-	-	S	-	-	-	Psort location Cytoplasmic, score
HFBHIDMB_02696	1.36e-244	acoA	-	-	C	ko:K21416	-	ko00000,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HFBHIDMB_02697	6.47e-243	acoB	-	-	C	ko:K21417	-	ko00000,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HFBHIDMB_02698	2.22e-260	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HFBHIDMB_02699	0.0	acoL	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HFBHIDMB_02700	0.0	acoR	-	-	KQ	ko:K21405	-	ko00000,ko03000	COG3284 Transcriptional activator of acetoin glycerol metabolism
HFBHIDMB_02701	8.16e-36	sspH	-	-	S	ko:K06425	-	ko00000	Belongs to the SspH family
HFBHIDMB_02702	1.05e-74	yfjF	-	-	S	ko:K09771	-	ko00000,ko02000	UPF0060 membrane protein
HFBHIDMB_02703	1.07e-100	-	-	-	S	-	-	-	Family of unknown function (DUF5381)
HFBHIDMB_02704	1.49e-131	yfjD	-	-	S	-	-	-	Family of unknown function (DUF5381)
HFBHIDMB_02705	2.5e-185	yfjC	-	-	-	-	-	-	-
HFBHIDMB_02706	2.26e-269	yfjB	-	-	-	-	-	-	-
HFBHIDMB_02707	5.59e-61	yfjA	-	-	S	-	-	-	Belongs to the WXG100 family
HFBHIDMB_02710	6.81e-25	-	-	-	S	-	-	-	protein conserved in bacteria
HFBHIDMB_02712	4.94e-88	-	-	-	S	-	-	-	LXG domain of WXG superfamily
HFBHIDMB_02715	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HFBHIDMB_02716	8.69e-181	-	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
HFBHIDMB_02717	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HFBHIDMB_02718	0.0	yobO	-	-	M	-	-	-	COG5434 Endopolygalacturonase
HFBHIDMB_02719	0.0	yfiB3	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HFBHIDMB_02720	0.0	yfiC3	-	-	V	ko:K06147	-	ko00000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HFBHIDMB_02721	2.01e-84	yfiD3	-	-	S	-	-	-	DoxX
HFBHIDMB_02722	2e-206	yfiE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
HFBHIDMB_02723	4.15e-240	baeS	-	-	T	-	-	-	Histidine kinase
HFBHIDMB_02724	1.01e-144	yfiK	-	-	KT	ko:K02479	-	ko00000,ko02022	LuxR family transcriptional regulator
HFBHIDMB_02725	5.1e-213	drrA	-	-	V	ko:K01990,ko:K09695	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HFBHIDMB_02726	1.78e-265	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HFBHIDMB_02727	4.19e-263	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
HFBHIDMB_02728	1.89e-128	padR	-	-	K	-	-	-	transcriptional
HFBHIDMB_02729	7.87e-128	lip	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HFBHIDMB_02730	9.34e-253	yfiQ	-	-	G	ko:K21462	-	ko00000	COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HFBHIDMB_02731	1.34e-137	yfiR	-	-	K	-	-	-	Transcriptional regulator
HFBHIDMB_02732	2.54e-271	yfiS	-	-	EGP	-	-	-	Major facilitator superfamily
HFBHIDMB_02733	1.15e-127	yfiT	-	-	S	-	-	-	Belongs to the metal hydrolase YfiT family
HFBHIDMB_02734	0.0	yfiU	-	-	EGP	-	-	-	the major facilitator superfamily
HFBHIDMB_02735	2.11e-103	yfiV	-	-	K	-	-	-	transcriptional
HFBHIDMB_02736	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HFBHIDMB_02737	3.83e-231	yfiY	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HFBHIDMB_02738	8.91e-225	yfiZ	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HFBHIDMB_02739	7.36e-229	yfhA	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HFBHIDMB_02740	1.58e-207	yfhB	-	-	S	-	-	-	PhzF family
HFBHIDMB_02741	1.66e-137	yfhC	-	-	C	-	-	-	nitroreductase
HFBHIDMB_02742	8.86e-35	yfhD	-	-	S	-	-	-	YfhD-like protein
HFBHIDMB_02744	8.92e-219	yfhF	-	-	S	ko:K07071	-	ko00000	nucleoside-diphosphate sugar epimerase
HFBHIDMB_02745	9.32e-181	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
HFBHIDMB_02746	4.58e-69	yfhH	-	-	S	-	-	-	Protein of unknown function (DUF1811)
HFBHIDMB_02748	2.45e-268	yfhI	-	-	EGP	-	-	-	-transporter
HFBHIDMB_02749	2.25e-27	sspK	-	-	S	ko:K06428	-	ko00000	reproduction
HFBHIDMB_02750	8.95e-60	yfhJ	-	-	S	-	-	-	WVELL protein
HFBHIDMB_02751	1.99e-116	yfhK	-	-	T	-	-	-	Bacterial SH3 domain homologues
HFBHIDMB_02752	1.66e-62	yfhL	-	-	S	-	-	-	SdpI/YhfL protein family
HFBHIDMB_02753	9.27e-217	yfhM	3.8.1.5	-	S	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Alpha beta hydrolase
HFBHIDMB_02754	3.43e-236	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
HFBHIDMB_02755	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HFBHIDMB_02756	2.07e-236	yfhP	-	-	S	ko:K07038	-	ko00000	membrane-bound metal-dependent
HFBHIDMB_02757	1.31e-265	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific
HFBHIDMB_02758	1.73e-48	yfhS	-	-	-	-	-	-	-
HFBHIDMB_02759	3.13e-172	fabL	1.3.1.104	-	IQ	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HFBHIDMB_02760	2.35e-14	sspE	-	-	S	ko:K06422	-	ko00000	Small, acid-soluble spore protein, gamma-type
HFBHIDMB_02761	8.19e-49	ygaB	-	-	S	-	-	-	YgaB-like protein
HFBHIDMB_02762	8.1e-136	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
HFBHIDMB_02763	0.0	ygaD	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
HFBHIDMB_02764	1.87e-238	ygaE	-	-	S	-	-	-	Membrane
HFBHIDMB_02765	1.33e-311	gsaB	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
HFBHIDMB_02766	2.92e-113	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Peroxiredoxin
HFBHIDMB_02767	2.37e-104	perR	-	-	P	ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HFBHIDMB_02768	3.38e-73	ygzB	-	-	S	-	-	-	UPF0295 protein
HFBHIDMB_02769	8.23e-215	ygxA	-	-	S	-	-	-	Nucleotidyltransferase-like
HFBHIDMB_02787	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HFBHIDMB_02788	8.49e-265	glgC	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HFBHIDMB_02789	3.72e-238	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Glucose-1-phosphate adenylyltransferase, GlgD subunit
HFBHIDMB_02790	0.0	glgA	2.4.1.21	GT5	G	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
HFBHIDMB_02791	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HFBHIDMB_02792	8.04e-101	ytaB	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	membrane
HFBHIDMB_02793	2.59e-260	cotI	-	-	S	ko:K06331	-	ko00000	Spore coat protein
HFBHIDMB_02794	1.75e-276	cotSA	-	-	M	ko:K06338	-	ko00000	Glycosyl transferases group 1
HFBHIDMB_02795	2.82e-262	cotS	-	-	S	ko:K06337	-	ko00000	Seems to be required for the assembly of the CotSA protein in spores
HFBHIDMB_02797	6.86e-296	-	-	-	M	ko:K06338	-	ko00000	Glycosyltransferase Family 4
HFBHIDMB_02798	5.23e-229	ytcB	-	-	M	-	-	-	NAD-dependent epimerase dehydratase
HFBHIDMB_02799	1.32e-306	ytcA	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HFBHIDMB_02800	1.7e-196	ytdA	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
HFBHIDMB_02801	1.01e-167	yteA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
HFBHIDMB_02802	0.0	menF	5.4.4.2	-	HQ	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
HFBHIDMB_02803	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HFBHIDMB_02804	6.65e-195	menH	4.2.99.20	-	S	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
HFBHIDMB_02805	3.45e-200	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HFBHIDMB_02806	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HFBHIDMB_02807	5.81e-272	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HFBHIDMB_02808	1.79e-215	troA	-	-	P	ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HFBHIDMB_02809	1.97e-175	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K11710,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HFBHIDMB_02810	4.31e-295	mntC	-	-	P	ko:K11705,ko:K11708,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HFBHIDMB_02811	9.24e-192	mntD	-	-	P	ko:K11709,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
HFBHIDMB_02812	2.43e-34	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1540)
HFBHIDMB_02813	1.15e-238	ythB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG1294 Cytochrome bd-type quinol oxidase, subunit 2
HFBHIDMB_02814	1.03e-315	ythA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
HFBHIDMB_02815	5.02e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HFBHIDMB_02816	8.96e-134	ytiB	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
HFBHIDMB_02817	8.36e-113	luxS	4.4.1.21	-	T	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HFBHIDMB_02818	4.78e-95	ytkA	-	-	S	-	-	-	YtkA-like
HFBHIDMB_02820	1.8e-99	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HFBHIDMB_02821	3.2e-81	ytkC	-	-	S	-	-	-	Bacteriophage holin family
HFBHIDMB_02822	4.47e-113	ytkD	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
HFBHIDMB_02823	1.32e-183	ytlD	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HFBHIDMB_02824	1.5e-184	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HFBHIDMB_02825	1.87e-240	ytlA	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HFBHIDMB_02826	5.48e-190	ytmA	-	-	E	-	-	-	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HFBHIDMB_02827	2.85e-52	ytmB	-	-	S	-	-	-	Protein of unknown function (DUF2584)
HFBHIDMB_02828	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HFBHIDMB_02829	2.26e-286	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HFBHIDMB_02830	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HFBHIDMB_02831	0.0	ytnA	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
HFBHIDMB_02832	8.35e-88	ytoA	-	-	S	-	-	-	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HFBHIDMB_02833	4.7e-192	ytpA	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Alpha beta hydrolase
HFBHIDMB_02834	4.81e-276	ytpB	4.2.3.130	-	S	ko:K16188	-	ko00000,ko01000	Tetraprenyl-beta-curcumene synthase
HFBHIDMB_02835	1.17e-133	ytqB	-	-	J	-	-	-	Putative rRNA methylase
HFBHIDMB_02836	2.35e-244	ytqA	-	-	S	ko:K07139	-	ko00000	Fe-S oxidoreductase
HFBHIDMB_02837	1.27e-55	ytzC	-	-	S	-	-	-	Protein of unknown function (DUF2524)
HFBHIDMB_02839	2.68e-87	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	GntR family transcriptional regulator
HFBHIDMB_02840	5.96e-207	ytrB	-	-	P	ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HFBHIDMB_02841	1.98e-214	-	-	-	P	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HFBHIDMB_02842	4.77e-193	-	-	-	-	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	-
HFBHIDMB_02843	5.88e-163	ytrE	-	-	V	ko:K16920	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HFBHIDMB_02844	6.15e-155	ytrF	-	-	V	ko:K02004,ko:K16918	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
HFBHIDMB_02845	1.09e-129	ytrF	-	-	V	ko:K02004,ko:K16918	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
HFBHIDMB_02846	1.7e-165	graR	-	-	T	ko:K11630,ko:K19078	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01504,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HFBHIDMB_02847	1.77e-236	bceS	2.7.13.3	-	T	ko:K11629,ko:K19077	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	His Kinase A (phosphoacceptor) domain
HFBHIDMB_02848	3.83e-179	bceA	-	-	V	ko:K02003,ko:K11631,ko:K19079	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter, ATP-binding protein
HFBHIDMB_02849	0.0	bceB	-	-	V	ko:K11632,ko:K19080	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter (permease)
HFBHIDMB_02850	5.75e-78	yttA	-	-	S	-	-	-	Pfam Transposase IS66
HFBHIDMB_02851	1.72e-268	yttB	-	-	EGP	-	-	-	Major facilitator superfamily
HFBHIDMB_02852	3.82e-183	pfyP	-	-	T	-	-	-	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
HFBHIDMB_02853	3.63e-72	ytvB	-	-	S	-	-	-	Protein of unknown function (DUF4257)
HFBHIDMB_02854	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HFBHIDMB_02855	4.98e-68	ytwF	-	-	P	-	-	-	Sulfurtransferase
HFBHIDMB_02856	0.0	melA	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
HFBHIDMB_02857	7.65e-186	amyC	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
HFBHIDMB_02858	1.66e-214	amyD	-	-	P	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HFBHIDMB_02859	8.99e-313	msmE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HFBHIDMB_02860	1.31e-243	msmR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HFBHIDMB_02861	2.66e-218	-	-	-	S	-	-	-	Acetyl xylan esterase (AXE1)
HFBHIDMB_02862	7.51e-178	bioW	6.2.1.14	-	H	ko:K01906	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
HFBHIDMB_02863	0.0	bioA	2.6.1.105, 2.6.1.62	-	H	ko:K00833,ko:K19563	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
HFBHIDMB_02864	2.58e-275	bioF	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HFBHIDMB_02865	2.68e-159	bioD	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HFBHIDMB_02866	2.53e-241	bioB	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HFBHIDMB_02867	1.06e-277	bioI	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
HFBHIDMB_02868	7.41e-177	ytbQ	1.1.1.203, 1.1.1.388	-	GM	ko:K18981,ko:K19243	ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	NAD dependent epimerase/dehydratase family
HFBHIDMB_02869	1.02e-191	ytcP	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
HFBHIDMB_02870	0.0	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
HFBHIDMB_02871	0.0	ytdP	-	-	K	-	-	-	Transcriptional regulator
HFBHIDMB_02872	1.31e-220	lplB13	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4209 ABC-type polysaccharide transport system, permease component
HFBHIDMB_02873	1.18e-278	yteR	3.2.1.172	GH105	G	ko:K15532	-	ko00000,ko01000	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HFBHIDMB_02874	6.78e-94	yteS	-	-	G	-	-	-	transport
HFBHIDMB_02875	0.0	yteT	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
HFBHIDMB_02876	3.13e-149	yteU	-	-	S	-	-	-	Integral membrane protein
HFBHIDMB_02877	2.14e-36	yteV	-	-	S	-	-	-	Sporulation protein Cse60
HFBHIDMB_02878	0.0	opuD	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
HFBHIDMB_02879	5.74e-293	ytfP	-	-	S	ko:K07007	-	ko00000	HI0933-like protein
HFBHIDMB_02880	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HFBHIDMB_02881	2.49e-168	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HFBHIDMB_02882	4.46e-46	ytzE	-	-	K	-	-	-	COG1349 Transcriptional regulators of sugar metabolism
HFBHIDMB_02883	2.8e-168	ythP	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HFBHIDMB_02884	4.99e-255	ythQ	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Bacterial ABC transporter protein EcsB
HFBHIDMB_02885	7.02e-288	pbuO	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HFBHIDMB_02886	0.0	ytjP	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Dipeptidase
HFBHIDMB_02887	3e-221	ytkP	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HFBHIDMB_02888	2.04e-128	ytlP	3.1.4.58	-	J	ko:K01975	-	ko00000,ko01000,ko03016	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HFBHIDMB_02889	8.15e-211	ytlQ	-	-	-	-	-	-	-
HFBHIDMB_02890	2.22e-231	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HFBHIDMB_02891	0.0	amyX	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HFBHIDMB_02892	3.02e-192	ytmP	-	-	M	-	-	-	Phosphotransferase
HFBHIDMB_02893	9.51e-61	ytzH	-	-	S	-	-	-	YtzH-like protein
HFBHIDMB_02894	8.79e-156	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HFBHIDMB_02895	1.3e-191	ytnP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
HFBHIDMB_02896	0.0	malS	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
HFBHIDMB_02897	3.34e-67	ytzB	-	-	S	-	-	-	small secreted protein
HFBHIDMB_02898	3.71e-261	pepA	3.4.11.7	-	G	ko:K01261,ko:K01269	-	ko00000,ko01000,ko01002	COG1363 Cellulase M and related proteins
HFBHIDMB_02899	7.02e-103	ytoQ	-	-	S	-	-	-	Nucleoside 2-deoxyribosyltransferase YtoQ
HFBHIDMB_02900	3.17e-75	ytpP	-	-	CO	-	-	-	Thioredoxin
HFBHIDMB_02901	1.02e-191	ytpQ	-	-	S	-	-	-	Belongs to the UPF0354 family
HFBHIDMB_02902	4.2e-139	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HFBHIDMB_02903	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HFBHIDMB_02904	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HFBHIDMB_02905	1.67e-63	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HFBHIDMB_02906	3.17e-30	ytxH	-	-	S	-	-	-	COG4980 Gas vesicle protein
HFBHIDMB_02907	2.23e-71	ytxJ	-	-	O	-	-	-	Protein of unknown function (DUF2847)
HFBHIDMB_02908	7.64e-250	aroA	2.5.1.54, 5.4.99.5	-	E	ko:K03856,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
HFBHIDMB_02909	4.16e-235	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HFBHIDMB_02910	6.84e-187	motP	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
HFBHIDMB_02911	1.6e-161	ytxE	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
HFBHIDMB_02912	1.81e-290	acuC	-	-	BQ	ko:K04768	-	ko00000	histone deacetylase
HFBHIDMB_02913	6.16e-152	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
HFBHIDMB_02914	2.43e-156	acuA	-	-	K	ko:K04766	-	ko00000,ko01000	Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
HFBHIDMB_02915	0.0	acsA	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HFBHIDMB_02916	5.31e-303	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HFBHIDMB_02918	2.01e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HFBHIDMB_02919	0.0	ytrP	-	-	T	-	-	-	COG2199 FOG GGDEF domain
HFBHIDMB_02920	3.24e-113	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
HFBHIDMB_02921	4.87e-141	yttP	-	-	K	-	-	-	Transcriptional regulator
HFBHIDMB_02922	5.29e-198	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	COG1387 Histidinol phosphatase and related hydrolases of the PHP family
HFBHIDMB_02923	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HFBHIDMB_02924	8.23e-305	braB	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HFBHIDMB_02925	1.3e-264	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
HFBHIDMB_02926	6.26e-289	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HFBHIDMB_02927	2.12e-40	-	-	-	S	ko:K06418,ko:K06419,ko:K06420	-	ko00000	spore protein
HFBHIDMB_02928	0.0	ytcI	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HFBHIDMB_02929	0.0	ytcJ	-	-	S	-	-	-	amidohydrolase
HFBHIDMB_02930	2.4e-189	nadK2	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HFBHIDMB_02931	8.34e-231	sppA	-	-	OU	ko:K04773	-	ko00000,ko01000,ko01002	signal peptide peptidase SppA
HFBHIDMB_02932	1.37e-110	yteJ	-	-	S	-	-	-	RDD family
HFBHIDMB_02933	8.34e-149	ytfI	-	-	S	-	-	-	Protein of unknown function (DUF2953)
HFBHIDMB_02934	1.06e-94	ytfJ	-	-	S	-	-	-	Sporulation protein YtfJ
HFBHIDMB_02935	1.93e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HFBHIDMB_02936	1.08e-223	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
HFBHIDMB_02937	4.69e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HFBHIDMB_02938	3.31e-114	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
HFBHIDMB_02939	1.06e-297	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HFBHIDMB_02940	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HFBHIDMB_02942	1.07e-61	ytkK	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HFBHIDMB_02943	9.65e-111	ytkK	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HFBHIDMB_02944	1.91e-166	ytkL	-	-	S	-	-	-	Belongs to the UPF0173 family
HFBHIDMB_02945	1.13e-308	ytoI	-	-	K	-	-	-	transcriptional regulator containing CBS domains
HFBHIDMB_02946	2.15e-63	ytpI	-	-	S	-	-	-	YtpI-like protein
HFBHIDMB_02947	1.24e-230	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	COG0618 Exopolyphosphatase-related proteins
HFBHIDMB_02948	1.15e-39	-	-	-	-	-	-	-	-
HFBHIDMB_02949	5.12e-112	ytrI	-	-	-	-	-	-	-
HFBHIDMB_02950	2.45e-75	ytrH	-	-	S	-	-	-	Sporulation protein YtrH
HFBHIDMB_02951	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HFBHIDMB_02952	8.53e-287	ytsJ	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
HFBHIDMB_02953	8.83e-208	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HFBHIDMB_02954	9.82e-234	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HFBHIDMB_02955	1.62e-229	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HFBHIDMB_02956	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HFBHIDMB_02957	3.16e-80	fxsA	-	-	S	ko:K07113	-	ko00000	COG3030 Protein affecting phage T7 exclusion by the F plasmid
HFBHIDMB_02958	2.73e-245	ytvI	-	-	S	-	-	-	sporulation integral membrane protein YtvI
HFBHIDMB_02959	9.38e-95	ytwI	-	-	S	-	-	-	membrane
HFBHIDMB_02960	1.17e-267	citZ	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
HFBHIDMB_02961	9.27e-309	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	isocitrate
HFBHIDMB_02962	1.04e-217	mdh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible oxidation of malate to oxaloacetate
HFBHIDMB_02963	1.62e-169	phoP	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HFBHIDMB_02964	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase
HFBHIDMB_02965	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HFBHIDMB_02966	1.77e-198	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HFBHIDMB_02967	1.68e-138	ytaF	-	-	P	-	-	-	Probably functions as a manganese efflux pump
HFBHIDMB_02968	3.84e-124	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HFBHIDMB_02969	4.54e-205	ytbE	-	-	S	-	-	-	reductase
HFBHIDMB_02970	5.2e-258	ytbD	-	-	EGP	ko:K19577	-	ko00000,ko02000	-transporter
HFBHIDMB_02971	1.15e-86	ytcD	-	-	K	-	-	-	Transcriptional regulator
HFBHIDMB_02972	1.22e-246	gapB	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HFBHIDMB_02973	2.42e-88	speH	4.1.1.50	-	E	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HFBHIDMB_02974	2.42e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HFBHIDMB_02975	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	Membrane attachment protein
HFBHIDMB_02976	1e-219	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HFBHIDMB_02977	1.33e-141	ytxB	-	-	S	-	-	-	SNARE associated Golgi protein
HFBHIDMB_02978	3.46e-205	ytxC	-	-	S	-	-	-	YtxC-like family
HFBHIDMB_02980	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HFBHIDMB_02981	1.98e-189	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
HFBHIDMB_02982	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HFBHIDMB_02983	1.96e-166	lytT	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
HFBHIDMB_02984	8.47e-85	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HFBHIDMB_02985	5.34e-150	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HFBHIDMB_02987	1.81e-111	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HFBHIDMB_02988	3.93e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HFBHIDMB_02989	3.26e-76	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HFBHIDMB_02990	3.65e-59	ysdA	-	-	S	-	-	-	Membrane
HFBHIDMB_02991	3.26e-88	ysdB	-	-	S	-	-	-	Sigma-w pathway protein YsdB
HFBHIDMB_02992	4.35e-262	ysdC	-	-	G	-	-	-	COG1363 Cellulase M and related proteins
HFBHIDMB_02993	9.92e-242	-	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
HFBHIDMB_02994	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
HFBHIDMB_02995	0.0	araB	2.7.1.16	-	C	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Belongs to the ribulokinase family
HFBHIDMB_02996	1.7e-170	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HFBHIDMB_02997	1.67e-184	araL	-	-	G	ko:K02101	-	ko00000	Haloacid dehalogenase-like hydrolase
HFBHIDMB_02998	7.5e-282	araM	1.1.1.261	-	I	ko:K00096	ko00564,map00564	ko00000,ko00001,ko01000	Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
HFBHIDMB_02999	0.0	araN	-	-	G	ko:K17234	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
HFBHIDMB_03000	1.59e-217	araP	-	-	G	ko:K17235	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
HFBHIDMB_03001	6.34e-192	araQ	-	-	G	ko:K17236	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport system permease
HFBHIDMB_03002	0.0	abfA	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	alpha-L-arabinofuranosidase activity
HFBHIDMB_03003	0.0	cstA	-	-	T	ko:K06200	-	ko00000	Carbon starvation protein
HFBHIDMB_03004	2.07e-69	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase-like domain
HFBHIDMB_03005	0.0	glcF	-	-	C	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	Glycolate oxidase
HFBHIDMB_03006	0.0	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Glycolate oxidase subunit
HFBHIDMB_03007	1.45e-259	cdaR_1	-	-	KT	ko:K02647	-	ko00000,ko03000	regulator
HFBHIDMB_03008	4.37e-43	sspI	-	-	S	ko:K06426	-	ko00000	Belongs to the SspI family
HFBHIDMB_03009	1.81e-170	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HFBHIDMB_03010	1.22e-248	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HFBHIDMB_03011	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HFBHIDMB_03012	8.48e-215	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HFBHIDMB_03013	1.04e-54	zapA	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HFBHIDMB_03014	1.09e-111	yshB	-	-	S	-	-	-	membrane protein, required for colicin V production
HFBHIDMB_03015	0.0	polX	-	-	L	ko:K02347	-	ko00000,ko03400	COG1796 DNA polymerase IV (family X)
HFBHIDMB_03016	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HFBHIDMB_03017	3.76e-89	yshE	-	-	S	ko:K08989	-	ko00000	membrane
HFBHIDMB_03018	0.0	lcfA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HFBHIDMB_03019	5.74e-129	fadR	-	-	K	ko:K13770	-	ko00000,ko03000	Transcriptional regulator
HFBHIDMB_03020	1.81e-175	fadB	4.2.1.17	-	I	ko:K13767	ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the enoyl-CoA hydratase isomerase family
HFBHIDMB_03021	2.58e-179	etfB	-	-	C	ko:K03521	-	ko00000	Electron transfer flavoprotein
HFBHIDMB_03022	3.02e-228	etfA	-	-	C	ko:K03522	-	ko00000,ko04147	Electron transfer flavoprotein
HFBHIDMB_03023	0.0	xsa	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
HFBHIDMB_03024	1.12e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HFBHIDMB_03025	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HFBHIDMB_03026	6.56e-274	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HFBHIDMB_03027	8.53e-104	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HFBHIDMB_03028	1.35e-140	sdhC	-	-	C	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	succinate dehydrogenase
HFBHIDMB_03029	0.0	sdhA	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
HFBHIDMB_03030	1.15e-189	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
HFBHIDMB_03031	2.65e-102	ysmA	-	-	S	ko:K07107	-	ko00000,ko01000	thioesterase
HFBHIDMB_03032	1.81e-41	gerE	-	-	K	ko:K01994	-	ko00000,ko03000	Transcriptional regulator
HFBHIDMB_03033	1.42e-49	ysmB	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HFBHIDMB_03034	4.49e-194	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HFBHIDMB_03035	8.03e-256	gerM	-	-	S	ko:K06298	-	ko00000	COG5401 Spore germination protein
HFBHIDMB_03036	3.53e-171	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HFBHIDMB_03037	7.86e-132	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HFBHIDMB_03038	1.65e-118	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HFBHIDMB_03040	6.77e-181	ysnF	-	-	S	-	-	-	protein conserved in bacteria
HFBHIDMB_03041	1.55e-44	ysnE	-	-	K	ko:K03829	-	ko00000,ko01000	acetyltransferase
HFBHIDMB_03043	0.0	ilvB	2.2.1.6	-	E	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
HFBHIDMB_03044	5.05e-110	ilvN	2.2.1.6	-	E	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
HFBHIDMB_03045	9.59e-245	ilvC	1.1.1.86	-	EH	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HFBHIDMB_03046	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HFBHIDMB_03047	8.67e-255	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HFBHIDMB_03048	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HFBHIDMB_03049	4.4e-149	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HFBHIDMB_03050	3.19e-239	ysoA	-	-	H	-	-	-	Tetratricopeptide repeat
HFBHIDMB_03051	2.54e-286	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HFBHIDMB_03052	1.15e-296	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HFBHIDMB_03053	0.0	lonB	3.4.21.53	-	LO	ko:K04076	-	ko00000,ko01000,ko01002	Belongs to the peptidase S16 family
HFBHIDMB_03054	0.0	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HFBHIDMB_03055	7.6e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HFBHIDMB_03056	4.77e-116	ysxD	-	-	-	-	-	-	-
HFBHIDMB_03057	6.39e-316	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HFBHIDMB_03058	6.56e-187	hemX	-	-	O	ko:K02497	-	ko00000	cytochrome C
HFBHIDMB_03059	8.91e-220	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HFBHIDMB_03060	1.23e-184	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
HFBHIDMB_03061	3.7e-233	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the ALAD family
HFBHIDMB_03062	3.53e-312	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
HFBHIDMB_03063	0.0	spoVID	-	-	M	ko:K06417	-	ko00000	stage VI sporulation protein D
HFBHIDMB_03064	2.79e-251	ysxE	-	-	S	-	-	-	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HFBHIDMB_03065	1.53e-35	-	-	-	-	-	-	-	-
HFBHIDMB_03066	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HFBHIDMB_03067	1.83e-314	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HFBHIDMB_03068	1.28e-108	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HFBHIDMB_03069	3.91e-207	spoIIB	-	-	S	ko:K06380	-	ko00000	Sporulation related domain
HFBHIDMB_03070	1.66e-130	maf	-	-	D	ko:K06287	-	ko00000	septum formation protein Maf
HFBHIDMB_03071	1.39e-161	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
HFBHIDMB_03072	5.26e-235	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein MreB
HFBHIDMB_03073	7.78e-202	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HFBHIDMB_03074	8.72e-111	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	shape-determining protein
HFBHIDMB_03075	4.3e-158	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HFBHIDMB_03076	2.91e-186	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
HFBHIDMB_03077	1.23e-185	spoIVFA	-	-	M	ko:K06401	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
HFBHIDMB_03078	3.74e-208	spoIVFB	-	-	S	ko:K06402	-	ko00000,ko01000,ko01002	Stage IV sporulation protein
HFBHIDMB_03079	6.34e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HFBHIDMB_03080	2.66e-74	ysxB	-	-	J	ko:K07584	-	ko00000	ribosomal protein
HFBHIDMB_03081	2.7e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HFBHIDMB_03082	4.25e-139	spo0B	-	-	T	ko:K06375	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01000	Sporulation initiation phospho-transferase B, C-terminal
HFBHIDMB_03083	5.59e-308	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HFBHIDMB_03084	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HFBHIDMB_03085	0.0	-	-	-	Q	ko:K15665	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HFBHIDMB_03087	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HFBHIDMB_03088	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HFBHIDMB_03089	0.0	-	6.3.2.14	-	Q	ko:K02364,ko:K15656,ko:K15668	ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024	ko00000,ko00001,ko01000,ko01008	amino acid activation for nonribosomal peptide biosynthetic process
HFBHIDMB_03090	2.48e-83	yngL	-	-	S	-	-	-	Protein of unknown function (DUF1360)
HFBHIDMB_03091	0.0	yngK	-	-	T	-	-	-	Glycosyl hydrolase-like 10
HFBHIDMB_03092	3.09e-267	yngJ	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
HFBHIDMB_03093	0.0	yngI	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HFBHIDMB_03094	2.81e-316	yngH	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase
HFBHIDMB_03095	8.37e-42	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin carboxyl carrier protein
HFBHIDMB_03096	9.56e-212	yngG	4.1.3.4	-	E	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA lyase
HFBHIDMB_03097	6.03e-175	yngF	-	-	I	-	-	-	Belongs to the enoyl-CoA hydratase isomerase family
HFBHIDMB_03098	0.0	yngE	-	-	I	-	-	-	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HFBHIDMB_03099	7.39e-296	yngD	-	-	S	ko:K07097	-	ko00000	phosphohydrolase (DHH superfamily)
HFBHIDMB_03100	2.01e-134	yngC	-	-	S	-	-	-	membrane-associated protein
HFBHIDMB_03101	5.53e-210	yngB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HFBHIDMB_03102	9.97e-103	yngA	-	-	S	-	-	-	membrane
HFBHIDMB_03103	0.0	xynD	3.2.1.55	CBM6,GH43	G	ko:K15921	ko00520,map00520	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
HFBHIDMB_03104	9.85e-317	ynfF	3.2.1.136	GH5	M	ko:K15924	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 30 family
HFBHIDMB_03106	0.0	bglC5	3.2.1.4	GH5,GH9	G	ko:K01179	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	PFAM glycoside hydrolase family 5
HFBHIDMB_03107	0.0	alsT	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
HFBHIDMB_03108	8.74e-75	ynfC	-	-	-	-	-	-	-
HFBHIDMB_03109	7.45e-18	-	-	-	-	-	-	-	-
HFBHIDMB_03110	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HFBHIDMB_03111	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HFBHIDMB_03112	1.72e-90	yneT	-	-	S	ko:K06929	-	ko00000	CoA-binding protein
HFBHIDMB_03113	5.48e-122	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HFBHIDMB_03114	8.97e-65	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
HFBHIDMB_03115	5.48e-70	yneQ	-	-	-	-	-	-	-
HFBHIDMB_03116	2.72e-93	yneP	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
HFBHIDMB_03117	2.22e-46	tlp	-	-	S	ko:K06434	-	ko00000	Belongs to the Tlp family
HFBHIDMB_03119	9.26e-10	-	-	-	S	-	-	-	Fur-regulated basic protein B
HFBHIDMB_03120	3.74e-120	yneN	-	-	CO	-	-	-	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HFBHIDMB_03121	0.0	citB	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HFBHIDMB_03122	3.75e-21	sspO	-	-	S	ko:K06432	-	ko00000	Belongs to the SspO family
HFBHIDMB_03123	5.65e-27	sspP	-	-	S	ko:K06433	-	ko00000	Belongs to the SspP family
HFBHIDMB_03124	5.77e-85	cotM	-	-	O	ko:K06335	-	ko00000	Spore coat protein
HFBHIDMB_03125	3.97e-97	yneK	-	-	S	-	-	-	Protein of unknown function (DUF2621)
HFBHIDMB_03126	2.51e-98	yneJ	-	-	O	-	-	-	COG4846 Membrane protein involved in cytochrome C biogenesis
HFBHIDMB_03127	7.38e-78	ccdB	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
HFBHIDMB_03128	1.68e-164	ccdA	-	-	O	ko:K06196	-	ko00000,ko02000	cytochrome c biogenesis protein
HFBHIDMB_03129	4.59e-21	ynzD	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
HFBHIDMB_03130	4.36e-39	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
HFBHIDMB_03131	2.18e-106	yneE	-	-	S	-	-	-	Sporulation inhibitor of replication protein sirA
HFBHIDMB_03132	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HFBHIDMB_03133	1.15e-43	ynzC	-	-	S	-	-	-	UPF0291 protein
HFBHIDMB_03134	2.29e-144	yneB	-	-	L	-	-	-	resolvase
HFBHIDMB_03135	2.44e-64	yneA	-	-	D	-	-	-	Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
HFBHIDMB_03136	7.22e-142	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HFBHIDMB_03137	2.47e-101	fosB	-	-	H	ko:K11210,ko:K21252	-	ko00000,ko01000,ko01504	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
HFBHIDMB_03138	3.79e-96	yndM	-	-	S	-	-	-	Protein of unknown function (DUF2512)
HFBHIDMB_03139	2.57e-172	yndL	-	-	S	-	-	-	Replication protein
HFBHIDMB_03141	0.0	yndJ	-	-	S	-	-	-	YndJ-like protein
HFBHIDMB_03142	1.21e-149	-	-	-	S	-	-	-	Domain of unknown function (DUF4166)
HFBHIDMB_03143	1.2e-194	yndG	-	-	S	-	-	-	DoxX-like family
HFBHIDMB_03144	5.12e-285	-	-	-	S	ko:K06293,ko:K06312	-	ko00000	Spore germination protein
HFBHIDMB_03145	9.26e-249	yndE7	-	-	U	ko:K06311	-	ko00000,ko02000	Spore germination
HFBHIDMB_03146	0.0	yndD1	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
HFBHIDMB_03149	1.81e-103	yndB	-	-	S	-	-	-	Activator of Hsp90 ATPase homolog 1-like protein
HFBHIDMB_03150	1.04e-94	-	-	-	-	-	-	-	-
HFBHIDMB_03151	2.37e-34	tatA	-	-	U	ko:K03116,ko:K03117,ko:K03646	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02000,ko02044	protein secretion
HFBHIDMB_03154	8.59e-170	-	-	-	S	-	-	-	Domain of unknown function, YrpD
HFBHIDMB_03156	1.12e-209	-	-	-	S	-	-	-	Thymidylate synthase
HFBHIDMB_03159	3.01e-102	yncF	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Deoxyuridine 5'-triphosphate
HFBHIDMB_03160	9.48e-108	-	-	-	S	-	-	-	Protein of unknown function (DUF2691)
HFBHIDMB_03162	5.91e-279	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HFBHIDMB_03163	0.0	-	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HFBHIDMB_03164	7.18e-145	yokF	3.1.31.1	-	L	ko:K01174	-	ko00000,ko01000	RNA catabolic process
HFBHIDMB_03165	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	xylulose kinase
HFBHIDMB_03166	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
HFBHIDMB_03167	5.23e-277	xylR	-	-	GK	-	-	-	ROK family
HFBHIDMB_03168	0.0	xynB	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
HFBHIDMB_03169	0.0	xynP	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
HFBHIDMB_03170	1.56e-103	-	-	-	E	-	-	-	phosphoribosylanthranilate isomerase activity
HFBHIDMB_03171	9.53e-160	-	-	-	S	-	-	-	Domain of unknown function (DUF3885)
HFBHIDMB_03172	5.75e-124	ynaD	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HFBHIDMB_03173	6.63e-122	-	-	-	G	-	-	-	SMI1-KNR4 cell-wall
HFBHIDMB_03174	4.15e-49	-	-	-	-	-	-	-	-
HFBHIDMB_03175	2.44e-155	-	-	-	-	-	-	-	-
HFBHIDMB_03177	2.16e-14	-	-	-	-	-	-	-	-
HFBHIDMB_03179	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HFBHIDMB_03180	4.05e-89	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	transcriptional
HFBHIDMB_03181	1.67e-310	ynbB	-	-	P	-	-	-	COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HFBHIDMB_03182	2.29e-226	spoVK	-	-	O	ko:K06413	-	ko00000	stage V sporulation protein K
HFBHIDMB_03183	2.72e-148	cwlC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
HFBHIDMB_03184	1.76e-138	-	-	-	-	-	-	-	-
HFBHIDMB_03185	6.73e-243	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HFBHIDMB_03186	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HFBHIDMB_03187	5.01e-66	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
HFBHIDMB_03188	1.2e-30	ymzA	-	-	-	-	-	-	-
HFBHIDMB_03189	1.63e-31	-	-	-	-	-	-	-	-
HFBHIDMB_03190	1.28e-45	hfq	-	-	J	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	ko00000,ko00001,ko03019,ko03036	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HFBHIDMB_03191	1.38e-223	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HFBHIDMB_03192	5.41e-76	ymaF	-	-	S	-	-	-	YmaF family
HFBHIDMB_03194	2.02e-66	ebrA	-	-	P	ko:K11814	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
HFBHIDMB_03195	2.23e-73	ebrB	-	-	P	ko:K03297,ko:K11814,ko:K11815	-	ko00000,ko00002,ko02000	COG2076 Membrane transporters of cations and cationic drugs
HFBHIDMB_03196	5.98e-105	ymaD	-	-	O	-	-	-	redox protein, regulator of disulfide bond formation
HFBHIDMB_03197	3.96e-163	ymaC	-	-	S	-	-	-	Replication protein
HFBHIDMB_03199	0.0	aprX	-	-	O	ko:K17734	-	ko00000,ko01000,ko01002	Belongs to the peptidase S8 family
HFBHIDMB_03200	2.67e-207	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HFBHIDMB_03201	8.03e-81	ymzB	-	-	-	-	-	-	-
HFBHIDMB_03202	1.24e-135	pksA	-	-	K	-	-	-	Transcriptional regulator
HFBHIDMB_03203	2.67e-125	ymcC	-	-	S	-	-	-	Membrane
HFBHIDMB_03205	1.91e-91	-	-	-	S	-	-	-	Regulatory protein YrvL
HFBHIDMB_03206	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HFBHIDMB_03207	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HFBHIDMB_03208	1.74e-119	cotE	-	-	S	ko:K06328	-	ko00000	Spore coat protein
HFBHIDMB_03209	1.27e-89	ymcA	3.6.3.21	-	S	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	Belongs to the UPF0342 family
HFBHIDMB_03210	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HFBHIDMB_03211	1.55e-273	kbl	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HFBHIDMB_03212	8.31e-253	tdh	1.1.1.103	-	C	ko:K00060	ko00260,map00260	ko00000,ko00001,ko01000	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
HFBHIDMB_03213	2.44e-49	spoVS	-	-	S	ko:K06416	-	ko00000	Stage V sporulation protein S
HFBHIDMB_03214	6.18e-195	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	protein conserved in bacteria
HFBHIDMB_03215	4.25e-306	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HFBHIDMB_03216	1.82e-276	pbpX	-	-	V	-	-	-	Beta-lactamase
HFBHIDMB_03217	4.7e-239	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HFBHIDMB_03218	3.71e-300	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HFBHIDMB_03219	3.34e-132	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HFBHIDMB_03220	8.75e-177	ymfM	-	-	S	ko:K15539	-	ko00000	protein conserved in bacteria
HFBHIDMB_03221	3.91e-183	ymfK	-	-	S	-	-	-	Protein of unknown function (DUF3388)
HFBHIDMB_03222	5.13e-55	ymfJ	-	-	S	-	-	-	Protein of unknown function (DUF3243)
HFBHIDMB_03223	3.01e-166	ymfI	1.1.1.100	-	S	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
HFBHIDMB_03224	3.37e-309	ymfH	-	-	S	-	-	-	zinc protease
HFBHIDMB_03225	4.5e-297	albE	-	-	S	-	-	-	Peptidase M16
HFBHIDMB_03226	5.1e-266	ymfD	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HFBHIDMB_03227	1.28e-171	ymfC	-	-	K	ko:K03710	-	ko00000,ko03000	Transcriptional regulator
HFBHIDMB_03228	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HFBHIDMB_03229	4.94e-44	-	-	-	S	-	-	-	YlzJ-like protein
HFBHIDMB_03230	5.01e-171	tepA	-	-	OU	-	-	-	COG0740 Protease subunit of ATP-dependent Clp proteases
HFBHIDMB_03231	0.0	rnjB	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HFBHIDMB_03232	6.39e-201	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HFBHIDMB_03233	4.9e-283	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HFBHIDMB_03234	5.56e-246	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HFBHIDMB_03235	8.17e-141	spoVFB	-	-	H	ko:K06411	-	ko00000	Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HFBHIDMB_03236	1.52e-207	dpaA	-	-	CH	ko:K06410	-	ko00000	Dipicolinate synthase subunit A
HFBHIDMB_03237	1.53e-56	ymxH	-	-	S	-	-	-	YlmC YmxH family
HFBHIDMB_03238	1.62e-295	mlpA	-	-	S	-	-	-	Belongs to the peptidase M16 family
HFBHIDMB_03239	2.4e-231	ylxY	-	-	G	-	-	-	Sporulation protein, polysaccharide deacetylase
HFBHIDMB_03240	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HFBHIDMB_03241	7.11e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HFBHIDMB_03242	2.22e-230	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HFBHIDMB_03243	6.04e-220	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HFBHIDMB_03244	3.29e-75	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HFBHIDMB_03245	1.11e-59	ylxP	-	-	S	ko:K09764	-	ko00000	protein conserved in bacteria
HFBHIDMB_03246	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HFBHIDMB_03247	6.16e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
HFBHIDMB_03248	1.66e-56	ylxR	-	-	K	ko:K07742	-	ko00000	nucleic-acid-binding protein implicated in transcription termination
HFBHIDMB_03249	5.49e-261	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HFBHIDMB_03250	1.34e-104	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HFBHIDMB_03251	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HFBHIDMB_03252	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HFBHIDMB_03253	4.72e-285	rasP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HFBHIDMB_03254	1.39e-276	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HFBHIDMB_03255	5.77e-179	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HFBHIDMB_03256	3.84e-187	uppS	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HFBHIDMB_03257	9.6e-119	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HFBHIDMB_03258	5.82e-163	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HFBHIDMB_03259	9.82e-202	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HFBHIDMB_03260	1.49e-168	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HFBHIDMB_03261	2.07e-69	ylxL	-	-	-	-	-	-	-
HFBHIDMB_03262	1.12e-13	ylxL	-	-	-	-	-	-	-
HFBHIDMB_03263	1.33e-175	sigD	-	-	K	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	ko00000,ko00001,ko02035,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HFBHIDMB_03264	3.34e-112	cheD	3.5.1.44	-	NT	ko:K03411	ko02030,map02030	ko00000,ko00001,ko01000,ko02035	Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HFBHIDMB_03265	5.06e-144	cheC	-	-	NT	ko:K03410	ko02030,map02030	ko00000,ko00001,ko02035	COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HFBHIDMB_03266	1.56e-103	cheW	-	-	NT	ko:K03408	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	COG0835 Chemotaxis signal transduction protein
HFBHIDMB_03267	0.0	cheA	2.7.13.3	-	NT	ko:K03407	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	COG0643 Chemotaxis protein histidine kinase and related kinases
HFBHIDMB_03268	1.81e-252	cheB	3.1.1.61, 3.5.1.44	-	NT	ko:K03412	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HFBHIDMB_03269	4.46e-200	ylxH	-	-	D	ko:K04562	-	ko00000,ko02035	Belongs to the ParA family
HFBHIDMB_03270	5.42e-254	flhF	-	-	N	ko:K02404	-	ko00000,ko02035	Flagellar biosynthesis regulator FlhF
HFBHIDMB_03271	0.0	flhA	-	-	N	ko:K02400	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HFBHIDMB_03272	3.89e-244	flhB	-	-	N	ko:K02401	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HFBHIDMB_03273	1.47e-170	fliR	-	-	N	ko:K02421	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthetic protein FliR
HFBHIDMB_03274	5.23e-50	fliQ	-	-	N	ko:K02420	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Role in flagellar biosynthesis
HFBHIDMB_03275	1.21e-141	fliP	-	-	N	ko:K02419	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Plays a role in the flagellum-specific transport system
HFBHIDMB_03276	7.87e-137	fliZ	-	-	N	ko:K02418	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthesis protein, FliO
HFBHIDMB_03277	1.22e-76	cheY	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	response regulator
HFBHIDMB_03278	1.38e-253	fliY	-	-	N	ko:K02417	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035,ko02044	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HFBHIDMB_03279	5.02e-220	fliM	-	-	N	ko:K02416	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HFBHIDMB_03280	5.59e-78	fliL	-	-	N	ko:K02415	-	ko00000,ko02035	Controls the rotational direction of flagella during chemotaxis
HFBHIDMB_03281	1.09e-179	flgG	-	-	N	ko:K02390	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod
HFBHIDMB_03282	2.81e-96	flgD	-	-	N	ko:K02389	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod modification protein
HFBHIDMB_03283	2.61e-304	fliK	-	-	N	ko:K02414	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-length control protein
HFBHIDMB_03284	1.51e-78	ylxF	-	-	S	-	-	-	MgtE intracellular N domain
HFBHIDMB_03285	1.79e-91	fliJ	-	-	N	ko:K02413	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar biosynthesis chaperone
HFBHIDMB_03286	1e-306	fliI	3.6.3.14	-	NU	ko:K02412	ko02040,map02040	ko00000,ko00001,ko01000,ko02035,ko02044	COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HFBHIDMB_03287	1.92e-144	fliH	-	-	NU	ko:K02411	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	COG1317 Flagellar biosynthesis type III secretory pathway protein
HFBHIDMB_03288	6.08e-230	fliG	-	-	N	ko:K02410	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HFBHIDMB_03289	0.0	fliF	-	-	N	ko:K02409	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	The M ring may be actively involved in energy transduction
HFBHIDMB_03290	5.5e-53	fliE	-	-	N	ko:K02408	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-basal body
HFBHIDMB_03291	8.81e-98	flgC	-	-	N	ko:K02388	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the flagella basal body rod proteins family
HFBHIDMB_03292	1.62e-83	flgB	-	-	N	ko:K02387	ko02040,map02040	ko00000,ko00001,ko02035	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HFBHIDMB_03293	1.95e-175	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HFBHIDMB_03294	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HFBHIDMB_03295	3.01e-120	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HFBHIDMB_03296	1.13e-217	xerC	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	tyrosine recombinase XerC
HFBHIDMB_03297	2.59e-312	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HFBHIDMB_03298	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HFBHIDMB_03299	3.62e-215	dprA	-	-	LU	ko:K04096	-	ko00000	Rossmann fold nucleotide-binding protein involved in DNA uptake
HFBHIDMB_03300	1.53e-213	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HFBHIDMB_03301	6.77e-269	sucC	6.2.1.5	-	C	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HFBHIDMB_03302	1.7e-59	ylqH	-	-	S	ko:K04061	-	ko00000,ko02044	homolog of the cytoplasmic domain of flagellar protein FhlB
HFBHIDMB_03303	0.0	ylqG	-	-	-	-	-	-	-
HFBHIDMB_03304	5.83e-175	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HFBHIDMB_03305	2.83e-200	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HFBHIDMB_03306	8.14e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HFBHIDMB_03307	2.41e-177	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HFBHIDMB_03308	1.84e-122	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HFBHIDMB_03309	9.77e-80	ylqD	-	-	S	-	-	-	YlqD protein
HFBHIDMB_03310	1.2e-49	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HFBHIDMB_03311	1.13e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HFBHIDMB_03312	3.95e-308	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HFBHIDMB_03313	8.01e-66	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HFBHIDMB_03314	1.67e-114	-	-	-	-	-	-	-	-
HFBHIDMB_03315	3.38e-227	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HFBHIDMB_03316	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HFBHIDMB_03317	2.12e-174	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HFBHIDMB_03318	1.15e-43	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HFBHIDMB_03319	3.5e-167	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HFBHIDMB_03320	4.39e-217	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
HFBHIDMB_03321	3.39e-229	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HFBHIDMB_03322	6.22e-121	fapR	-	-	K	-	-	-	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HFBHIDMB_03323	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HFBHIDMB_03324	1.19e-201	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
HFBHIDMB_03325	1.45e-153	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
HFBHIDMB_03326	0.0	yloV	-	-	S	ko:K07030	-	ko00000	kinase related to dihydroxyacetone kinase
HFBHIDMB_03327	3.65e-78	yloU	-	-	S	-	-	-	protein conserved in bacteria
HFBHIDMB_03328	7.06e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HFBHIDMB_03329	8.13e-157	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HFBHIDMB_03330	9.44e-153	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HFBHIDMB_03331	4.57e-214	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HFBHIDMB_03332	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HFBHIDMB_03333	2.05e-179	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HFBHIDMB_03334	3.07e-263	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HFBHIDMB_03335	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HFBHIDMB_03336	1.05e-224	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HFBHIDMB_03337	4.8e-109	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HFBHIDMB_03338	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HFBHIDMB_03339	4.21e-285	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HFBHIDMB_03340	6.21e-39	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HFBHIDMB_03341	5.73e-143	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HFBHIDMB_03342	3.97e-54	ylzA	-	-	S	ko:K09777	-	ko00000	Belongs to the UPF0296 family
HFBHIDMB_03343	8.41e-202	yloC	-	-	S	-	-	-	stress-induced protein
HFBHIDMB_03344	0.0	yloB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	COG0474 Cation transport ATPase
HFBHIDMB_03345	0.0	FbpA	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
HFBHIDMB_03346	5.37e-107	sirC	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Siroheme synthase
HFBHIDMB_03347	2.5e-188	sirB	4.99.1.4	-	S	ko:K03794	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sirohydrochlorin ferrochelatase
HFBHIDMB_03348	4.85e-184	cobA	2.1.1.107	-	H	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
HFBHIDMB_03349	1.59e-141	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
HFBHIDMB_03350	2.62e-285	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
HFBHIDMB_03351	1.41e-227	cysP	-	-	P	ko:K16331	-	ko00000,ko02000	phosphate transporter
HFBHIDMB_03352	5.95e-182	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
HFBHIDMB_03354	8.96e-149	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HFBHIDMB_03355	2.67e-163	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HFBHIDMB_03356	2.46e-220	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HFBHIDMB_03357	4.31e-182	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HFBHIDMB_03358	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarB family
HFBHIDMB_03359	1.31e-269	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HFBHIDMB_03360	0.0	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HFBHIDMB_03361	2.97e-213	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HFBHIDMB_03362	2.24e-295	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Xanthine uracil
HFBHIDMB_03363	4.45e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HFBHIDMB_03364	8.3e-224	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HFBHIDMB_03365	2.71e-103	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HFBHIDMB_03366	2.63e-82	ylyA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
HFBHIDMB_03367	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HFBHIDMB_03368	6.44e-100	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	Cell division initiation protein
HFBHIDMB_03369	1.74e-177	ylmH	-	-	S	-	-	-	conserved protein, contains S4-like domain
HFBHIDMB_03370	1.22e-53	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	membrane
HFBHIDMB_03371	1.28e-86	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HFBHIDMB_03372	1.28e-161	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HFBHIDMB_03373	9.17e-204	ylmD	-	-	S	ko:K05810	-	ko00000,ko01000	Belongs to the multicopper oxidase YfiH RL5 family
HFBHIDMB_03374	3.58e-51	ylmC	-	-	S	-	-	-	sporulation protein
HFBHIDMB_03375	0.0	argE	-	-	E	ko:K20895	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Acetylornithine deacetylase
HFBHIDMB_03376	1.83e-187	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HFBHIDMB_03377	7.99e-180	sigG	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HFBHIDMB_03378	1.48e-160	sigE	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HFBHIDMB_03379	2.05e-218	spoIIGA	-	-	M	ko:K06383	-	ko00000,ko01000,ko01002	aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HFBHIDMB_03380	0.0	bpr	-	-	O	ko:K13276	-	ko00000,ko01000,ko01002,ko03110	COG1404 Subtilisin-like serine proteases
HFBHIDMB_03381	4.18e-103	bpr	-	-	O	ko:K13276	-	ko00000,ko01000,ko01002,ko03110	COG1404 Subtilisin-like serine proteases
HFBHIDMB_03382	1.84e-260	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HFBHIDMB_03383	4.88e-299	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HFBHIDMB_03384	5.37e-76	sbp	-	-	S	-	-	-	small basic protein
HFBHIDMB_03385	1.5e-132	ylxX	-	-	S	-	-	-	protein conserved in bacteria
HFBHIDMB_03386	1.35e-143	ylxW	-	-	S	-	-	-	protein conserved in bacteria
HFBHIDMB_03387	3.37e-178	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HFBHIDMB_03388	3.74e-211	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	cell wall formation
HFBHIDMB_03389	1.82e-255	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HFBHIDMB_03390	6.64e-237	spoVE	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HFBHIDMB_03391	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HFBHIDMB_03392	9.59e-220	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HFBHIDMB_03393	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HFBHIDMB_03394	0.0	spoVD	-	-	M	ko:K08384	ko00550,map00550	ko00000,ko00001,ko01011	stage V sporulation protein D
HFBHIDMB_03395	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HFBHIDMB_03396	3.42e-68	ftsL	-	-	D	-	-	-	Essential cell division protein
HFBHIDMB_03397	1.66e-218	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HFBHIDMB_03398	9.82e-102	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HFBHIDMB_03399	0.0	bshC	-	-	S	ko:K22136	-	ko00000	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HFBHIDMB_03400	5.34e-213	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HFBHIDMB_03401	1.33e-115	ylbP	-	-	K	-	-	-	n-acetyltransferase
HFBHIDMB_03402	4.72e-107	ylbO	-	-	S	ko:K06314	-	ko00000,ko03000	SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HFBHIDMB_03403	1.71e-37	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HFBHIDMB_03404	6.94e-117	ylbN	-	-	S	ko:K07040	-	ko00000	metal-binding, possibly nucleic acid-binding protein
HFBHIDMB_03406	7.11e-293	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HFBHIDMB_03407	2.24e-238	ylbL	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HFBHIDMB_03408	2.56e-176	ylbK	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
HFBHIDMB_03409	9.11e-281	ylbJ	-	-	S	-	-	-	Sporulation integral membrane protein YlbJ
HFBHIDMB_03410	3.8e-111	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HFBHIDMB_03411	6.07e-126	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Methyltransferase
HFBHIDMB_03412	4.36e-52	ylbG	-	-	S	-	-	-	UPF0298 protein
HFBHIDMB_03413	2.34e-97	ylbF	-	-	S	-	-	-	Belongs to the UPF0342 family
HFBHIDMB_03414	1.73e-48	ylbE	-	-	S	-	-	-	YlbE-like protein
HFBHIDMB_03415	9.28e-89	ylbD	-	-	S	-	-	-	Putative coat protein
HFBHIDMB_03416	4.39e-256	ylbC	-	-	S	-	-	-	protein with SCP PR1 domains
HFBHIDMB_03417	1.08e-97	ylbB	-	-	T	-	-	-	COG0517 FOG CBS domain
HFBHIDMB_03418	1.61e-81	ylbA	-	-	S	-	-	-	YugN-like family
HFBHIDMB_03419	1.21e-213	ctaG	-	-	S	ko:K02862	-	ko00000	cytochrome c oxidase
HFBHIDMB_03420	6.09e-70	ctaF	1.9.3.1	-	C	ko:K02277	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HFBHIDMB_03421	1.84e-145	ctaE	1.9.3.1	-	C	ko:K02276	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HFBHIDMB_03422	0.0	ctaD	1.9.3.1	-	C	ko:K02274	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HFBHIDMB_03423	2.38e-252	ctaC	1.9.3.1	-	C	ko:K02275	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HFBHIDMB_03424	1.7e-208	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HFBHIDMB_03425	2.85e-212	ctaA	-	-	O	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	ko00000,ko00001,ko00002,ko03029	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HFBHIDMB_03426	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HFBHIDMB_03427	7.05e-271	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HFBHIDMB_03428	6.94e-59	ylaN	-	-	S	-	-	-	Belongs to the UPF0358 family
HFBHIDMB_03429	2.87e-218	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HFBHIDMB_03430	9.32e-112	ylaL	-	-	S	-	-	-	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HFBHIDMB_03431	3.76e-316	ylaK	-	-	T	ko:K07175	-	ko00000	ATPase related to phosphate starvation-inducible protein PhoH
HFBHIDMB_03432	2.97e-127	ylaJ	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HFBHIDMB_03433	8.92e-44	ylaI	-	-	S	-	-	-	protein conserved in bacteria
HFBHIDMB_03434	4.4e-63	ylaH	-	-	S	-	-	-	YlaH-like protein
HFBHIDMB_03435	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HFBHIDMB_03436	2.21e-30	-	-	-	S	-	-	-	Family of unknown function (DUF5325)
HFBHIDMB_03437	1.74e-57	ylaE	-	-	-	-	-	-	-
HFBHIDMB_03439	3.56e-115	ylaC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HFBHIDMB_03440	1.44e-56	ylaB	-	-	-	-	-	-	-
HFBHIDMB_03441	0.0	ylaA	-	-	-	-	-	-	-
HFBHIDMB_03442	0.0	mpl	3.4.24.28, 3.4.24.29	-	E	ko:K01400,ko:K01401,ko:K19351	ko01503,ko05150,map01503,map05150	ko00000,ko00001,ko01000,ko01002	Peptidase M4
HFBHIDMB_03443	7.08e-221	-	-	-	Q	-	-	-	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HFBHIDMB_03444	2.45e-99	ykzC	-	-	S	-	-	-	Acetyltransferase (GNAT) family
HFBHIDMB_03445	9.48e-195	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase
HFBHIDMB_03446	4.48e-35	ykzI	-	-	-	-	-	-	-
HFBHIDMB_03447	1.25e-150	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
HFBHIDMB_03448	1.34e-56	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
HFBHIDMB_03449	0.0	speA	4.1.1.17, 4.1.1.19	-	E	ko:K01581,ko:K01585	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Arginine
HFBHIDMB_03450	4.55e-83	slp	-	-	CO	-	-	-	COG0526, thiol-disulfide isomerase and thioredoxins
HFBHIDMB_03451	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HFBHIDMB_03452	7.26e-299	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HFBHIDMB_03453	3.52e-227	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HFBHIDMB_03454	1.06e-258	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HFBHIDMB_03455	6.82e-149	ykyA	-	-	L	-	-	-	Putative cell-wall binding lipoprotein
HFBHIDMB_03456	2.24e-19	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
HFBHIDMB_03457	1.14e-130	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HFBHIDMB_03458	4.79e-186	ykrA	-	-	S	-	-	-	hydrolases of the HAD superfamily
HFBHIDMB_03459	8.98e-42	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HFBHIDMB_03460	0.0	rnjA	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HFBHIDMB_03461	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HFBHIDMB_03462	1.68e-148	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
HFBHIDMB_03463	2.41e-198	ykqA	-	-	P	-	-	-	Gamma-glutamyl cyclotransferase, AIG2-like
HFBHIDMB_03464	2.65e-306	kinC	2.7.13.3	-	T	ko:K07698	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
HFBHIDMB_03465	2.63e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	of stationary sporulation gene expression
HFBHIDMB_03466	6.17e-234	mreBH	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod-share determining protein MreBH
HFBHIDMB_03467	6.35e-18	-	-	-	S	-	-	-	Uncharacterized protein YkpC
HFBHIDMB_03468	2.07e-303	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	COG2309 Leucyl aminopeptidase (aminopeptidase T)
HFBHIDMB_03469	5.54e-213	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HFBHIDMB_03470	0.0	ykpA	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HFBHIDMB_03471	5.43e-52	ykoA	-	-	-	-	-	-	-
HFBHIDMB_03472	1.72e-134	sipT	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HFBHIDMB_03473	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HFBHIDMB_03474	4.07e-215	pfkB	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family
HFBHIDMB_03475	7.41e-176	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	Transcriptional regulator
HFBHIDMB_03476	1.11e-264	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
HFBHIDMB_03477	6.1e-160	yknY	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFBHIDMB_03478	1.16e-233	yknX	-	-	M	ko:K02005,ko:K13888	-	ko00000,ko00002,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HFBHIDMB_03479	5.97e-147	yknW	-	-	S	-	-	-	Yip1 domain
HFBHIDMB_03480	0.0	yknV	-	-	V	ko:K02021,ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HFBHIDMB_03481	0.0	yknU	-	-	V	ko:K06147,ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HFBHIDMB_03482	2.82e-44	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HFBHIDMB_03483	6.61e-110	moaE	2.8.1.12	-	H	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	COG0314 Molybdopterin converting factor, large subunit
HFBHIDMB_03484	1.99e-121	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
HFBHIDMB_03485	4.29e-313	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	molybdopterin
HFBHIDMB_03486	2.54e-243	moeB	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HFBHIDMB_03487	2.17e-140	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HFBHIDMB_03488	3.3e-198	yknT	-	-	-	ko:K06437	-	ko00000	-
HFBHIDMB_03489	1.78e-120	rok	-	-	K	-	-	-	Repressor of ComK
HFBHIDMB_03490	6.01e-104	ykuV	-	-	CO	-	-	-	thiol-disulfide
HFBHIDMB_03491	9.78e-130	ykuU	-	-	O	-	-	-	Alkyl hydroperoxide reductase
HFBHIDMB_03492	4.1e-181	ykuT	-	-	M	ko:K22044	-	ko00000,ko02000	Mechanosensitive ion channel
HFBHIDMB_03493	7.23e-51	ykuS	-	-	S	-	-	-	Belongs to the UPF0180 family
HFBHIDMB_03494	1.27e-272	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HFBHIDMB_03495	1.31e-125	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HFBHIDMB_03496	1.2e-100	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HFBHIDMB_03497	1.18e-220	ykuO	-	-	-	-	-	-	-
HFBHIDMB_03498	1.44e-109	-	-	-	C	ko:K03839	-	ko00000	Flavodoxin domain
HFBHIDMB_03499	6.52e-216	ccpC	-	-	K	-	-	-	Transcriptional regulator
HFBHIDMB_03500	5.15e-100	ykuL	-	-	S	-	-	-	CBS domain
HFBHIDMB_03501	7.83e-38	ykzF	-	-	S	-	-	-	Antirepressor AbbA
HFBHIDMB_03502	6.44e-122	-	-	-	S	ko:K09776	-	ko00000	Ribonuclease H-like
HFBHIDMB_03503	5.16e-50	ykuJ	-	-	S	-	-	-	protein conserved in bacteria
HFBHIDMB_03504	7.16e-298	ykuI	-	-	T	-	-	-	Diguanylate phosphodiesterase
HFBHIDMB_03505	1.06e-181	fadH	1.3.1.34	-	IQ	ko:K00219	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HFBHIDMB_03506	3.48e-212	ykuE	-	-	S	ko:K07098	-	ko00000	Metallophosphoesterase
HFBHIDMB_03507	5.84e-115	ykuD	-	-	S	-	-	-	protein conserved in bacteria
HFBHIDMB_03508	1.04e-304	ykuC	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HFBHIDMB_03509	2.15e-109	ykyB	-	-	S	-	-	-	YkyB-like protein
HFBHIDMB_03510	4.95e-216	cheV	-	-	T	ko:K03408,ko:K03415	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	Chemotaxis protein CheV
HFBHIDMB_03511	1.05e-22	-	-	-	-	-	-	-	-
HFBHIDMB_03512	3.44e-282	patA	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HFBHIDMB_03513	0.0	kinA	2.7.13.3	-	T	ko:K02491	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HFBHIDMB_03514	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HFBHIDMB_03515	1.04e-169	ykwD	-	-	J	-	-	-	protein with SCP PR1 domains
HFBHIDMB_03516	1.68e-17	vgb	-	-	H	ko:K18235	-	ko00000,ko01000,ko01504	Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid
HFBHIDMB_03517	1.4e-203	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HFBHIDMB_03518	0.0	mcpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HFBHIDMB_03519	4.2e-160	ykwB	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HFBHIDMB_03520	2.49e-256	splB	4.1.99.14	-	L	ko:K03716	-	ko00000,ko01000	Spore photoproduct lyase
HFBHIDMB_03521	1.54e-51	splA	-	-	S	ko:K06315	-	ko00000,ko03000	Transcriptional regulator
HFBHIDMB_03522	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HFBHIDMB_03523	1.51e-53	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPr
HFBHIDMB_03524	0.0	ptsG	2.7.1.199	-	G	ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HFBHIDMB_03525	6.87e-168	glcT	-	-	K	ko:K03480,ko:K03488	-	ko00000,ko03000	antiterminator
HFBHIDMB_03527	5.43e-229	ykvZ	-	-	K	-	-	-	Transcriptional regulator
HFBHIDMB_03529	1.93e-264	ykvY	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
HFBHIDMB_03530	3.99e-09	-	-	-	-	-	-	-	-
HFBHIDMB_03531	0.0	zosA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
HFBHIDMB_03532	5.79e-117	stoA	-	-	CO	-	-	-	thiol-disulfide
HFBHIDMB_03533	9.18e-302	ykvU	-	-	S	-	-	-	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HFBHIDMB_03534	9.09e-142	ykvT	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell Wall Hydrolase
HFBHIDMB_03535	2.5e-39	-	-	-	-	-	-	-	-
HFBHIDMB_03536	5.43e-35	ykvS	-	-	S	-	-	-	protein conserved in bacteria
HFBHIDMB_03537	2.67e-62	ykvR	-	-	S	-	-	-	Protein of unknown function (DUF3219)
HFBHIDMB_03538	7.68e-172	ykvO	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HFBHIDMB_03539	2.8e-81	ykvN	-	-	K	-	-	-	Transcriptional regulator
HFBHIDMB_03540	2.36e-125	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HFBHIDMB_03541	3.56e-179	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HFBHIDMB_03542	6.96e-105	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	synthase
HFBHIDMB_03543	6.42e-161	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HFBHIDMB_03544	3.35e-227	ykvI	-	-	S	-	-	-	membrane
HFBHIDMB_03545	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HFBHIDMB_03546	1.65e-177	motA	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
HFBHIDMB_03547	1.64e-168	motB	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
HFBHIDMB_03548	5.17e-99	ykvE	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
HFBHIDMB_03549	0.0	kinD	2.7.13.3	-	T	ko:K13532	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
HFBHIDMB_03550	5.84e-95	eag	-	-	-	-	-	-	-
HFBHIDMB_03552	8.82e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF1232)
HFBHIDMB_03553	8.7e-123	mtnD	1.13.11.53, 1.13.11.54	-	S	ko:K08967	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HFBHIDMB_03554	4.34e-145	mtnB	4.2.1.109	-	E	ko:K08964	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
HFBHIDMB_03555	1.77e-175	mtnX	3.1.3.87	-	E	ko:K08966	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
HFBHIDMB_03556	9.72e-295	mtnW	5.3.2.5	-	G	ko:K08965	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
HFBHIDMB_03557	1.96e-295	mtnE	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HFBHIDMB_03558	4.7e-192	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HFBHIDMB_03559	1.43e-292	mtnK	2.7.1.100	-	F	ko:K00899	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HFBHIDMB_03560	3.8e-252	mtnA	5.3.1.23	-	E	ko:K08963	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HFBHIDMB_03562	4.58e-114	ogt	2.1.1.63	-	L	ko:K00567,ko:K13531	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HFBHIDMB_03563	0.0	kinE	2.7.13.3	-	T	ko:K13533	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HFBHIDMB_03564	3.34e-244	ykrP	-	-	G	-	-	-	COG3594 Fucose 4-O-acetylase and related acetyltransferases
HFBHIDMB_03565	1.77e-28	ykzE	-	-	-	-	-	-	-
HFBHIDMB_03567	2.58e-310	ktrD	-	-	P	-	-	-	COG0168 Trk-type K transport systems, membrane components
HFBHIDMB_03568	3.97e-199	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HFBHIDMB_03569	1.55e-159	ykrK	-	-	S	-	-	-	Domain of unknown function (DUF1836)
HFBHIDMB_03570	1.4e-36	sspD	-	-	S	ko:K06421	-	ko00000	small acid-soluble spore protein
HFBHIDMB_03571	9.93e-200	rsgI	-	-	S	-	-	-	Anti-sigma factor N-terminus
HFBHIDMB_03572	1.8e-167	sigI	-	-	K	ko:K03093	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HFBHIDMB_03573	4.63e-227	ykoY	-	-	P	-	-	-	COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HFBHIDMB_03574	1.71e-143	ykoX	-	-	S	-	-	-	membrane-associated protein
HFBHIDMB_03575	0.0	ykoW	2.7.7.65	-	T	ko:K21023	ko02025,map02025	ko00000,ko00001,ko01000	Diguanylate cyclase
HFBHIDMB_03576	5.94e-203	ku	-	-	L	ko:K10979	ko03450,map03450	ko00000,ko00001,ko03400	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HFBHIDMB_03577	0.0	ligD	6.5.1.1	-	L	ko:K01971	ko03450,map03450	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA ligase
HFBHIDMB_03578	8.13e-239	ykoT	-	-	M	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
HFBHIDMB_03579	0.0	ykoS	-	-	-	-	-	-	-
HFBHIDMB_03580	2.42e-195	ykoQ	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
HFBHIDMB_03581	2.38e-127	ykoP	-	-	G	-	-	-	polysaccharide deacetylase
HFBHIDMB_03582	3.68e-275	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
HFBHIDMB_03583	9.83e-106	ykoM	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
HFBHIDMB_03584	2.51e-35	ykoL	-	-	-	-	-	-	-
HFBHIDMB_03585	3.3e-25	-	-	-	-	-	-	-	-
HFBHIDMB_03586	1.49e-70	tnrA	-	-	K	-	-	-	transcriptional
HFBHIDMB_03587	9.86e-300	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
HFBHIDMB_03589	1.45e-08	-	-	-	-	-	-	-	-
HFBHIDMB_03590	5.28e-111	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HFBHIDMB_03591	9.6e-146	ykoI	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HFBHIDMB_03592	1.42e-305	ykoH	-	-	T	-	-	-	Histidine kinase
HFBHIDMB_03593	1.01e-157	ykoG	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HFBHIDMB_03594	2.97e-143	ykoF	-	-	S	-	-	-	YKOF-related Family
HFBHIDMB_03595	1.39e-127	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HFBHIDMB_03596	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HFBHIDMB_03597	3.12e-174	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HFBHIDMB_03598	8.04e-193	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HFBHIDMB_03599	1.49e-225	isp	-	-	O	ko:K13275	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HFBHIDMB_03600	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HFBHIDMB_03601	5.67e-115	guaD	3.5.4.3	-	FJ	ko:K01487	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	COG0590 Cytosine adenosine deaminases
HFBHIDMB_03602	8.15e-94	ohrB	-	-	O	-	-	-	Organic hydroperoxide resistance protein
HFBHIDMB_03603	1.42e-97	ohrR	-	-	K	-	-	-	COG1846 Transcriptional regulators
HFBHIDMB_03604	9.38e-91	ohrA	-	-	O	-	-	-	Organic hydroperoxide resistance protein
HFBHIDMB_03605	1.87e-288	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HFBHIDMB_03606	1.5e-255	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HFBHIDMB_03607	1.66e-217	purU	3.5.1.10	-	F	ko:K01433	ko00630,ko00670,map00630,map00670	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HFBHIDMB_03608	1.36e-66	ykkD	-	-	P	ko:K18925	-	ko00000,ko00002,ko02000	Multidrug resistance protein
HFBHIDMB_03609	7.34e-72	ykkC	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Multidrug resistance protein
HFBHIDMB_03610	2.43e-126	ykkB	-	-	J	-	-	-	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HFBHIDMB_03611	6.42e-128	ykkA	-	-	S	-	-	-	Protein of unknown function (DUF664)
HFBHIDMB_03612	3.95e-167	ykjA	-	-	S	-	-	-	Protein of unknown function (DUF421)
HFBHIDMB_03613	2.11e-16	-	-	-	-	-	-	-	-
HFBHIDMB_03614	1.26e-287	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HFBHIDMB_03615	1.55e-119	ykhA	-	-	I	-	-	-	Acyl-CoA hydrolase
HFBHIDMB_03616	2.53e-205	ykgA	-	-	E	-	-	-	Amidinotransferase
HFBHIDMB_03617	5.69e-261	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconolactonase
HFBHIDMB_03618	2.42e-236	ykfD	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HFBHIDMB_03619	1.78e-210	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HFBHIDMB_03620	1.55e-253	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
HFBHIDMB_03621	2.64e-222	ykfA	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
HFBHIDMB_03623	0.0	dppE	-	-	E	ko:K16199	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HFBHIDMB_03624	2.43e-239	dppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HFBHIDMB_03625	3.02e-224	dppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HFBHIDMB_03626	5.61e-203	dppB	-	-	P	ko:K16200	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HFBHIDMB_03627	3.29e-195	dppA	-	-	E	ko:K16203	-	ko00000,ko01000,ko01002	D-aminopeptidase
HFBHIDMB_03628	3.2e-176	proG	1.5.1.2	-	E	ko:K00286,ko:K02239	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko02044	Pyrroline-5-carboxylate reductase
HFBHIDMB_03629	1.39e-283	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HFBHIDMB_03631	2.21e-229	ykcC	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
HFBHIDMB_03632	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HFBHIDMB_03634	1.63e-232	ykcA	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
HFBHIDMB_03635	1.09e-310	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HFBHIDMB_03636	1.85e-144	ykaA	-	-	P	ko:K07220	-	ko00000	COG1392 Phosphate transport regulator (distant homolog of PhoU)
HFBHIDMB_03637	1.54e-225	pit	-	-	P	ko:K03306	-	ko00000	phosphate transporter
HFBHIDMB_03638	1.19e-175	spoIISA	-	-	S	ko:K06388	-	ko00000	Toxin SpoIISA, type II toxin-antitoxin system
HFBHIDMB_03639	1.78e-31	spoIISB	-	-	S	ko:K06389	-	ko00000	Stage II sporulation protein SB
HFBHIDMB_03640	5.76e-212	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
HFBHIDMB_03641	8.12e-53	xhlB	-	-	S	-	-	-	SPP1 phage holin
HFBHIDMB_03642	7.71e-52	xhlA	-	-	S	-	-	-	Haemolysin XhlA
HFBHIDMB_03643	6.16e-198	xepA	-	-	-	-	-	-	-
HFBHIDMB_03644	1.1e-31	xkdX	-	-	-	-	-	-	-
HFBHIDMB_03645	5.66e-70	xkdW	-	-	S	-	-	-	XkdW protein
HFBHIDMB_03646	0.0	-	-	-	-	-	-	-	-
HFBHIDMB_03647	4.43e-56	-	-	-	-	-	-	-	-
HFBHIDMB_03648	6.51e-134	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2313)
HFBHIDMB_03649	1.26e-243	-	-	-	S	-	-	-	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HFBHIDMB_03650	3.82e-90	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
HFBHIDMB_03651	1.45e-51	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
HFBHIDMB_03652	2.31e-232	xkdQ	-	-	G	-	-	-	NLP P60 protein
HFBHIDMB_03653	4.25e-152	xkdP	-	-	S	-	-	-	Lysin motif
HFBHIDMB_03654	0.0	xkdO	-	-	L	-	-	-	Transglycosylase SLT domain
HFBHIDMB_03655	9.21e-99	-	-	-	S	-	-	-	Phage XkdN-like tail assembly chaperone protein, TAC
HFBHIDMB_03656	6.01e-99	xkdM	-	-	S	-	-	-	Phage tail tube protein
HFBHIDMB_03657	0.0	xkdK	-	-	S	-	-	-	Phage tail sheath C-terminal domain
HFBHIDMB_03658	2.87e-101	xkdJ	-	-	-	-	-	-	-
HFBHIDMB_03659	2.38e-114	xkdI	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
HFBHIDMB_03660	2.91e-83	yqbH	-	-	S	-	-	-	Domain of unknown function (DUF3599)
HFBHIDMB_03661	6.64e-82	yqbG	-	-	S	-	-	-	Protein of unknown function (DUF3199)
HFBHIDMB_03662	3.91e-217	xkdG	-	-	S	-	-	-	Phage capsid family
HFBHIDMB_03663	1.4e-176	xkdF3	-	-	L	-	-	-	Putative phage serine protease XkdF
HFBHIDMB_03664	0.0	yqbA	-	-	S	-	-	-	portal protein
HFBHIDMB_03665	0.0	xtmB	-	-	S	ko:K06909	-	ko00000	phage terminase, large subunit
HFBHIDMB_03666	4.58e-177	xtmA	-	-	L	ko:K07474	-	ko00000	phage terminase small subunit
HFBHIDMB_03667	8.12e-110	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HFBHIDMB_03671	7.48e-153	xkdC	-	-	L	-	-	-	Bacterial dnaA protein
HFBHIDMB_03672	3.73e-203	xkdB	-	-	K	-	-	-	sequence-specific DNA binding
HFBHIDMB_03674	2.01e-74	xre	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HFBHIDMB_03675	1.53e-144	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
HFBHIDMB_03676	4.54e-204	yjqC	-	-	P	ko:K07217	-	ko00000	Catalase
HFBHIDMB_03677	1.3e-137	yjqB	-	-	S	-	-	-	Pfam:DUF867
HFBHIDMB_03678	1.35e-80	yjqA	-	-	S	-	-	-	Bacterial PH domain
HFBHIDMB_03679	5.34e-218	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
HFBHIDMB_03680	1.79e-55	-	-	-	S	-	-	-	YCII-related domain
HFBHIDMB_03682	7.06e-271	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
HFBHIDMB_03683	1.23e-313	VCP	-	-	O	-	-	-	AAA domain (dynein-related subfamily)
HFBHIDMB_03684	2.71e-103	yjoA	-	-	S	-	-	-	DinB family
HFBHIDMB_03685	1.31e-166	yjnA	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HFBHIDMB_03686	0.0	uxaA	4.2.1.42, 4.2.1.7	-	G	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
HFBHIDMB_03687	0.0	uxaB	1.1.1.58	-	G	ko:K00041	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	tagaturonate reductase activity
HFBHIDMB_03688	9.87e-238	exuR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
HFBHIDMB_03689	3.93e-289	exuT	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	Sugar (and other) transporter
HFBHIDMB_03690	2.23e-195	yjmF	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HFBHIDMB_03691	1.08e-270	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
HFBHIDMB_03692	1.86e-245	yjmD	1.1.1.380	-	E	ko:K08322	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
HFBHIDMB_03693	1.2e-240	allD	1.1.1.350	-	C	ko:K00073	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000	Belongs to the LDH2 MDH2 oxidoreductase family
HFBHIDMB_03694	1.19e-311	-	-	-	G	ko:K03292	-	ko00000	symporter YjmB
HFBHIDMB_03695	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
HFBHIDMB_03696	4.33e-280	yjlD	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HFBHIDMB_03697	1.39e-87	yjlC	-	-	S	-	-	-	Protein of unknown function (DUF1641)
HFBHIDMB_03698	2.36e-116	yjlB	-	-	S	-	-	-	Cupin domain
HFBHIDMB_03699	8.95e-225	yjlA	-	-	EG	-	-	-	Putative multidrug resistance efflux transporter
HFBHIDMB_03700	2.79e-175	yjkB	-	-	P	ko:K02068	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HFBHIDMB_03701	9.04e-156	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	transport system, permease component
HFBHIDMB_03702	8.69e-189	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
HFBHIDMB_03703	1.11e-41	-	-	-	-	-	-	-	-
HFBHIDMB_03704	1.19e-277	yjiC	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HFBHIDMB_03705	1.16e-286	yjiB	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
HFBHIDMB_03707	1.45e-144	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HFBHIDMB_03709	1.6e-122	yjgD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
HFBHIDMB_03710	0.0	yjgC	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase (NAD+) activity
HFBHIDMB_03711	4.96e-133	yjgB	-	-	S	-	-	-	Domain of unknown function (DUF4309)
HFBHIDMB_03712	3.78e-45	yjgA	-	-	T	-	-	-	Protein of unknown function (DUF2809)
HFBHIDMB_03713	4.5e-61	yjfC	-	-	O	-	-	-	Predicted Zn-dependent protease (DUF2268)
HFBHIDMB_03714	1.27e-133	yjfC	-	-	O	-	-	-	Predicted Zn-dependent protease (DUF2268)
HFBHIDMB_03715	1.13e-29	yjfB	-	-	S	-	-	-	Putative motility protein
HFBHIDMB_03716	8.68e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF2690)
HFBHIDMB_03717	0.0	yjeA	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
HFBHIDMB_03719	5.08e-222	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HFBHIDMB_03720	2.31e-69	yjdJ	-	-	S	-	-	-	Domain of unknown function (DUF4306)
HFBHIDMB_03721	6.12e-40	-	-	-	S	-	-	-	Domain of unknown function (DUF4177)
HFBHIDMB_03722	8.3e-105	ebsC	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HFBHIDMB_03724	1.47e-116	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HFBHIDMB_03725	7.58e-75	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
HFBHIDMB_03726	3.58e-240	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HFBHIDMB_03727	0.0	manP	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HFBHIDMB_03728	0.0	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	transcriptional antiterminator
HFBHIDMB_03729	8.47e-59	yjcN	-	-	-	-	-	-	-
HFBHIDMB_03730	2.59e-22	yjcS	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HFBHIDMB_03731	4.48e-23	yjcS	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HFBHIDMB_03732	2.49e-07	-	-	-	-	-	-	-	-
HFBHIDMB_03733	2.28e-25	-	-	-	-	-	-	-	-
HFBHIDMB_03734	1.92e-47	-	-	-	-	-	-	-	-
HFBHIDMB_03738	2.51e-19	-	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
HFBHIDMB_03740	6.79e-11	-	-	-	S	-	-	-	Family of unknown function (DUF5316)
HFBHIDMB_03742	1.8e-87	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
HFBHIDMB_03743	0.0	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HFBHIDMB_03744	4.49e-136	rapK	-	-	S	ko:K06369	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
HFBHIDMB_03750	4.34e-94	-	-	-	S	-	-	-	peptidoglycan catabolic process
HFBHIDMB_03751	5.35e-61	-	-	-	K	-	-	-	Helix-turn-helix domain
HFBHIDMB_03752	8.18e-07	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HFBHIDMB_03753	3.71e-96	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HFBHIDMB_03754	7.5e-80	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
HFBHIDMB_03755	1.38e-66	-	-	-	L	-	-	-	COG2963 Transposase and inactivated derivatives
HFBHIDMB_03756	4.17e-103	-	-	-	-	-	-	-	-
HFBHIDMB_03757	7.6e-12	-	-	-	S	-	-	-	Helix-turn-helix domain
HFBHIDMB_03758	4.48e-21	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HFBHIDMB_03759	1.31e-57	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HFBHIDMB_03760	2.65e-85	-	-	-	-	-	-	-	-
HFBHIDMB_03761	1.19e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF4064)
HFBHIDMB_03762	1.74e-09	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
HFBHIDMB_03763	1.4e-42	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
HFBHIDMB_03764	1.11e-22	int7	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HFBHIDMB_03765	8.66e-49	int7	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HFBHIDMB_03768	7.08e-272	yjcL	-	-	S	-	-	-	Protein of unknown function (DUF819)
HFBHIDMB_03769	3.47e-64	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Alanine acetyltransferase
HFBHIDMB_03770	3.96e-45	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Alanine acetyltransferase
HFBHIDMB_03771	1.84e-280	metC	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HFBHIDMB_03772	4.65e-272	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HFBHIDMB_03773	4.68e-178	yjcH	-	-	P	ko:K07214	-	ko00000	COG2382 Enterochelin esterase and related enzymes
HFBHIDMB_03774	1.2e-121	yjcG	-	-	J	-	-	-	Belongs to the 2H phosphoesterase superfamily. YjcG family
HFBHIDMB_03775	7.75e-94	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HFBHIDMB_03776	6.31e-51	-	-	-	-	-	-	-	-
HFBHIDMB_03777	0.0	yjcD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HFBHIDMB_03778	1.88e-52	spoVIF	-	-	S	-	-	-	Stage VI sporulation protein F
HFBHIDMB_03781	3.03e-76	yjcA	-	-	S	-	-	-	Protein of unknown function (DUF1360)
HFBHIDMB_03782	1.44e-72	cotV	-	-	S	ko:K06340	-	ko00000	Spore Coat Protein X and V domain
HFBHIDMB_03783	1.08e-54	cotW	-	-	-	ko:K06341	-	ko00000	-
HFBHIDMB_03784	2.38e-71	cotX	-	-	S	ko:K06342	-	ko00000	Spore Coat Protein X and V domain
HFBHIDMB_03785	3.12e-124	cotY	-	-	S	ko:K06343	-	ko00000	Spore coat protein Z
HFBHIDMB_03786	4.57e-108	cotZ	-	-	S	ko:K06344	-	ko00000	Spore coat protein
HFBHIDMB_03787	1.47e-103	yjbX	-	-	S	-	-	-	Spore coat protein
HFBHIDMB_03788	1.23e-182	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
HFBHIDMB_03789	8.38e-192	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HFBHIDMB_03790	1.52e-238	thiF	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HFBHIDMB_03791	6.78e-174	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HFBHIDMB_03792	1.8e-40	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	thiamine diphosphate biosynthetic process
HFBHIDMB_03793	4.44e-275	thiO	1.4.3.19, 1.4.5.1	-	E	ko:K00285,ko:K03153	ko00360,ko00730,ko01100,map00360,map00730,map01100	ko00000,ko00001,ko01000	Glycine oxidase
HFBHIDMB_03794	5.47e-137	tenI	5.3.99.10	-	H	ko:K10810	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Transcriptional regulator TenI
HFBHIDMB_03795	1.64e-176	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HFBHIDMB_03796	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HFBHIDMB_03797	8.09e-181	prpE	3.1.3.16, 3.6.1.41	-	T	ko:K01090,ko:K01525	ko00230,map00230	ko00000,ko00001,ko01000	Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
HFBHIDMB_03798	9.01e-204	rluD	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HFBHIDMB_03799	2.94e-194	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HFBHIDMB_03800	5.06e-145	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	GTP pyrophosphokinase
HFBHIDMB_03801	1.87e-81	yjbL	-	-	S	-	-	-	Belongs to the UPF0738 family
HFBHIDMB_03802	1.72e-128	yjbK	-	-	S	-	-	-	protein conserved in bacteria
HFBHIDMB_03803	6.89e-127	yjbJ	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HFBHIDMB_03804	8.58e-94	yjbI	-	-	S	ko:K06886	-	ko00000	Bacterial-like globin
HFBHIDMB_03805	1.32e-218	yjbH	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
HFBHIDMB_03807	2.68e-28	-	-	-	-	-	-	-	-
HFBHIDMB_03808	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
HFBHIDMB_03809	1.71e-279	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HFBHIDMB_03810	4.65e-149	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HFBHIDMB_03811	7.1e-144	yjbE	-	-	P	-	-	-	Integral membrane protein TerC family
HFBHIDMB_03812	1.01e-87	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HFBHIDMB_03813	8.88e-132	yjbC	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HFBHIDMB_03814	3.35e-260	yjbB	-	-	EGP	-	-	-	Major Facilitator Superfamily
HFBHIDMB_03815	1.27e-219	oppF	-	-	E	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HFBHIDMB_03816	1.37e-249	oppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HFBHIDMB_03817	7.55e-212	oppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HFBHIDMB_03818	1.03e-212	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HFBHIDMB_03819	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HFBHIDMB_03820	6.15e-235	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
HFBHIDMB_03821	7.51e-189	yjbA	-	-	S	-	-	-	Belongs to the UPF0736 family
HFBHIDMB_03822	1.03e-208	appC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HFBHIDMB_03823	3.73e-213	appB	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HFBHIDMB_03824	0.0	appA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
HFBHIDMB_03825	1.99e-235	appF	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HFBHIDMB_03826	6.15e-234	appD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HFBHIDMB_03827	9.48e-193	yjaZ	-	-	O	-	-	-	Zn-dependent protease
HFBHIDMB_03828	3.06e-302	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HFBHIDMB_03829	1.61e-221	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HFBHIDMB_03830	2.67e-38	yjzB	-	-	-	-	-	-	-
HFBHIDMB_03831	1.07e-35	comZ	-	-	S	ko:K02254	-	ko00000,ko02044	ComZ
HFBHIDMB_03832	6.4e-235	med	-	-	S	ko:K05519,ko:K07335	-	ko00000,ko03000	Transcriptional activator protein med
HFBHIDMB_03833	5.41e-134	yjaV	-	-	-	-	-	-	-
HFBHIDMB_03834	2.42e-182	yjaU	-	-	I	-	-	-	carboxylic ester hydrolase activity
HFBHIDMB_03835	2.17e-23	yjzD	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HFBHIDMB_03836	2.51e-39	yjzC	-	-	S	-	-	-	YjzC-like protein
HFBHIDMB_03837	1.49e-225	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HFBHIDMB_03838	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase ammonia chain
HFBHIDMB_03839	1.4e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HFBHIDMB_03840	1.69e-278	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
HFBHIDMB_03841	3.12e-176	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
HFBHIDMB_03842	7.4e-295	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HFBHIDMB_03843	7.41e-255	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HFBHIDMB_03844	3.24e-114	yitZ	-	-	G	-	-	-	Major Facilitator Superfamily
HFBHIDMB_03845	0.0	yitY	-	-	C	-	-	-	D-arabinono-1,4-lactone oxidase
HFBHIDMB_03846	1.74e-31	-	-	-	S	-	-	-	Proteolipid membrane potential modulator
HFBHIDMB_03847	3.26e-68	yitW	-	-	S	-	-	-	metal-sulfur cluster biosynthetic enzyme
HFBHIDMB_03848	5.05e-185	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
HFBHIDMB_03849	3.19e-200	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
HFBHIDMB_03850	1.92e-08	-	-	-	-	-	-	-	-
HFBHIDMB_03851	4.11e-25	-	-	-	S	-	-	-	Protein of unknown function (DUF3813)
HFBHIDMB_03852	9.69e-94	ipi	-	-	S	-	-	-	Intracellular proteinase inhibitor
HFBHIDMB_03853	2.29e-189	yitT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HFBHIDMB_03854	6.16e-200	yitS	-	-	S	-	-	-	protein conserved in bacteria
HFBHIDMB_03855	0.0	nprB	3.4.24.28	-	E	ko:K01400,ko:K08777	ko02024,map02024	ko00000,ko00001,ko01000,ko01002	Peptidase M4
HFBHIDMB_03856	5.37e-58	yitR	-	-	S	-	-	-	Domain of unknown function (DUF3784)
HFBHIDMB_03857	6.83e-117	-	-	-	-	-	-	-	-
HFBHIDMB_03858	2.08e-77	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HFBHIDMB_03859	3.29e-127	-	-	-	S	-	-	-	Sporulation delaying protein SdpA
HFBHIDMB_03860	4.76e-217	-	-	-	-	-	-	-	-
HFBHIDMB_03861	4.16e-122	-	-	-	-	-	-	-	-
HFBHIDMB_03862	2.75e-204	yitL	-	-	S	ko:K00243	-	ko00000	protein conserved in bacteria
HFBHIDMB_03863	1.75e-76	yitK	-	-	S	ko:K09767	-	ko00000	Belongs to the UPF0234 family
HFBHIDMB_03864	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HFBHIDMB_03865	8.44e-91	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HFBHIDMB_03866	2.39e-192	yitH	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HFBHIDMB_03867	8.28e-291	yitG	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HFBHIDMB_03868	6.13e-283	yitF	5.5.1.27	-	M	ko:K18983	ko00053,map00053	ko00000,ko00001,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
HFBHIDMB_03869	6.77e-145	yitE	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HFBHIDMB_03870	4.31e-180	yitD	4.4.1.19	-	S	ko:K08097	ko00680,ko01120,map00680,map01120	ko00000,ko00001,ko00002,ko01000	synthase
HFBHIDMB_03871	3.84e-162	-	3.1.3.71	-	H	ko:K05979	ko00680,ko01120,map00680,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the ComB family
HFBHIDMB_03872	9.51e-185	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
HFBHIDMB_03873	1.37e-295	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
HFBHIDMB_03874	4.06e-145	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
HFBHIDMB_03875	2.25e-199	yisY	1.11.1.10	-	I	ko:K00433	-	ko00000,ko01000	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HFBHIDMB_03876	2.15e-96	yisX	-	-	S	-	-	-	Pentapeptide repeats (9 copies)
HFBHIDMB_03877	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HFBHIDMB_03878	5.19e-138	argO	-	-	S	ko:K06895	-	ko00000,ko02000	Lysine exporter protein LysE YggA
HFBHIDMB_03879	1.72e-120	yisT	-	-	S	-	-	-	DinB family
HFBHIDMB_03880	1.73e-247	yisS	1.1.1.18, 1.1.1.369, 1.1.1.370	-	S	ko:K00010,ko:K16043	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
HFBHIDMB_03881	3.04e-234	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HFBHIDMB_03882	1.41e-207	yisR	-	-	K	-	-	-	Transcriptional regulator
HFBHIDMB_03883	2.91e-310	yisQ	-	-	V	-	-	-	Mate efflux family protein
HFBHIDMB_03884	8.91e-189	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	phytoene
HFBHIDMB_03885	1.07e-114	yizA	-	-	S	-	-	-	Damage-inducible protein DinB
HFBHIDMB_03886	0.0	asnO	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HFBHIDMB_03887	2.49e-130	yisN	-	-	S	-	-	-	Protein of unknown function (DUF2777)
HFBHIDMB_03888	0.0	wprA	-	-	O	ko:K13274	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HFBHIDMB_03889	1.02e-74	yisL	-	-	S	-	-	-	UPF0344 protein
HFBHIDMB_03890	2.66e-219	yisK	-	-	Q	-	-	-	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HFBHIDMB_03891	2.11e-219	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
HFBHIDMB_03892	1.52e-32	yisI	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
HFBHIDMB_03893	1.82e-45	gerPA	-	-	S	ko:K06299	-	ko00000	Spore germination protein
HFBHIDMB_03894	1.76e-47	gerPB	-	-	S	ko:K06300	-	ko00000	cell differentiation
HFBHIDMB_03895	3.34e-92	gerPC	-	-	S	ko:K06301	-	ko00000	Spore germination protein
HFBHIDMB_03896	1.49e-33	gerPD	-	-	S	ko:K06302	-	ko00000	Spore germination protein
HFBHIDMB_03897	4.58e-85	gerPE	-	-	S	ko:K06303	-	ko00000	Spore germination protein GerPE
HFBHIDMB_03898	3.3e-43	gerPF	-	-	S	ko:K06299,ko:K06304	-	ko00000	Spore germination protein gerPA/gerPF
HFBHIDMB_03899	1.84e-64	yisB	-	-	V	-	-	-	COG1403 Restriction endonuclease
HFBHIDMB_03900	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	COG0419 ATPase involved in DNA repair
HFBHIDMB_03901	1.4e-280	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HFBHIDMB_03902	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HFBHIDMB_03903	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	ATP-dependent helicase deoxyribonuclease subunit B
HFBHIDMB_03904	9.3e-102	yhjR	-	-	S	-	-	-	Rubrerythrin
HFBHIDMB_03905	0.0	-	-	-	S	-	-	-	Sugar transport-related sRNA regulator N-term
HFBHIDMB_03906	3.34e-268	-	-	-	EGP	-	-	-	Transmembrane secretion effector
HFBHIDMB_03907	1.02e-258	yhjN	-	-	S	ko:K07120	-	ko00000	membrane
HFBHIDMB_03908	3.58e-238	yhjM	-	-	K	-	-	-	Transcriptional regulator
HFBHIDMB_03909	0.0	-	2.6.1.104	-	E	ko:K18653	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
HFBHIDMB_03910	5.31e-205	ntdB	3.1.3.24, 3.1.3.92	-	S	ko:K07024,ko:K18654	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose-6F-phosphate phosphohydrolase
HFBHIDMB_03911	1.14e-256	-	1.1.1.18, 1.1.1.361, 1.1.1.369	-	S	ko:K00010,ko:K18652	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
HFBHIDMB_03912	1.42e-269	glcP	-	-	G	ko:K08174	-	ko00000,ko02000	Major Facilitator Superfamily
HFBHIDMB_03913	3.85e-120	yhjH	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HFBHIDMB_03914	0.0	yhjG	-	-	CH	-	-	-	FAD binding domain
HFBHIDMB_03915	5.12e-117	spsB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HFBHIDMB_03916	4.87e-141	yhjE	-	-	S	-	-	-	SNARE associated Golgi protein
HFBHIDMB_03917	2.12e-77	yhjD	-	-	-	-	-	-	-
HFBHIDMB_03918	1.61e-36	yhjC	-	-	S	-	-	-	Protein of unknown function (DUF3311)
HFBHIDMB_03919	0.0	yhjB	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HFBHIDMB_03920	2.04e-56	yhjA	-	-	S	-	-	-	Excalibur calcium-binding domain
HFBHIDMB_03921	1.04e-215	yhxD	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HFBHIDMB_03922	6.29e-141	comK	-	-	K	ko:K02250	ko02024,map02024	ko00000,ko00001,ko02044,ko03000	Competence transcription factor
HFBHIDMB_03923	9.84e-45	yhzC	-	-	S	-	-	-	IDEAL
HFBHIDMB_03924	2.24e-203	yhxC	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HFBHIDMB_03925	0.0	yhfW	-	-	CE	-	-	-	COG0665 Glycine D-amino acid oxidases (deaminating)
HFBHIDMB_03926	1.85e-260	hemAT	-	-	NT	ko:K06595	-	ko00000,ko02035	chemotaxis protein
HFBHIDMB_03927	1.47e-118	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HFBHIDMB_03928	0.0	vraA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
HFBHIDMB_03929	1.39e-255	yhfS	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
HFBHIDMB_03930	1.95e-140	yhfR	5.4.2.12	-	G	ko:K15634,ko:K15640	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphoglycerate mutase family
HFBHIDMB_03931	6.52e-222	yhfQ	-	-	M	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HFBHIDMB_03932	1.97e-231	yhfP	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Quinone oxidoreductase
HFBHIDMB_03933	1.47e-100	-	-	-	K	-	-	-	acetyltransferase
HFBHIDMB_03934	6.91e-260	aprE	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HFBHIDMB_03935	1.08e-304	yhfN	-	-	O	-	-	-	Peptidase M48
HFBHIDMB_03936	2.28e-84	yhfM	-	-	-	-	-	-	-
HFBHIDMB_03937	0.0	yhfL	6.2.1.3	-	IQ	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
HFBHIDMB_03938	2.48e-142	yhfK	-	-	GM	-	-	-	NmrA-like family
HFBHIDMB_03939	3.34e-244	lplJ	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HFBHIDMB_03940	5.93e-183	yhfI	-	-	S	-	-	-	COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
HFBHIDMB_03941	4.77e-289	gltT	-	-	C	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HFBHIDMB_03942	1.53e-93	-	-	-	S	-	-	-	ASCH
HFBHIDMB_03943	1.55e-252	yhfE	-	-	G	-	-	-	peptidase M42
HFBHIDMB_03944	3.8e-177	yhfC	-	-	S	-	-	-	Putative membrane peptidase family (DUF2324)
HFBHIDMB_03945	8.77e-237	fabHB	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HFBHIDMB_03946	0.0	yhgE	-	-	S	ko:K01421	-	ko00000	YhgE Pip N-terminal domain protein
HFBHIDMB_03947	5.79e-132	yhgD	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
HFBHIDMB_03948	0.0	hemY	1.3.3.15, 1.3.3.4	-	H	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HFBHIDMB_03949	3.99e-230	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
HFBHIDMB_03950	1.29e-259	hemE	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HFBHIDMB_03951	0.0	pbpF	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HFBHIDMB_03952	1.31e-118	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
HFBHIDMB_03953	2.72e-44	-	-	-	C	-	-	-	Rubrerythrin
HFBHIDMB_03954	7.73e-312	yhfA	-	-	C	-	-	-	membrane
HFBHIDMB_03955	6.27e-291	yhaA	-	-	E	ko:K01436	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HFBHIDMB_03956	7.62e-157	ecsC	-	-	S	-	-	-	EcsC protein family
HFBHIDMB_03957	2.55e-271	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HFBHIDMB_03958	1.28e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	transporter (ATP-binding protein)
HFBHIDMB_03959	3.5e-106	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HFBHIDMB_03960	2.15e-261	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HFBHIDMB_03961	6.32e-104	trpP	-	-	S	-	-	-	Tryptophan transporter TrpP
HFBHIDMB_03962	1.74e-54	yhaH	-	-	S	-	-	-	YtxH-like protein
HFBHIDMB_03963	4.92e-148	hpr	-	-	K	ko:K09682	-	ko00000,ko03000	Negative regulator of protease production and sporulation
HFBHIDMB_03964	8.48e-73	yhaI	-	-	S	-	-	-	Protein of unknown function (DUF1878)
HFBHIDMB_03965	3.3e-115	yhaK	-	-	S	-	-	-	Putative zincin peptidase
HFBHIDMB_03966	2.33e-161	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HFBHIDMB_03967	1.88e-39	yhaL	-	-	S	-	-	-	Sporulation protein YhaL
HFBHIDMB_03968	5.22e-228	yhaM	-	-	L	ko:K03698	-	ko00000,ko01000,ko03019	Shows a 3'-5' exoribonuclease activity
HFBHIDMB_03969	0.0	yhaN	-	-	L	-	-	-	AAA domain
HFBHIDMB_03970	9.44e-301	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	DNA repair exonuclease
HFBHIDMB_03971	5.14e-272	yhaP	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	COG1668 ABC-type Na efflux pump, permease component
HFBHIDMB_03972	4.57e-214	yhaQ	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFBHIDMB_03973	9.36e-36	-	-	-	S	-	-	-	YhzD-like protein
HFBHIDMB_03974	8.52e-168	yhaR	-	-	I	-	-	-	enoyl-CoA hydratase
HFBHIDMB_03976	6.51e-114	-	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
HFBHIDMB_03977	1.85e-267	yhaU	-	-	P	ko:K03455	-	ko00000	COG0475 Kef-type K transport systems, membrane components
HFBHIDMB_03978	0.0	hemZ	-	-	H	-	-	-	coproporphyrinogen III oxidase
HFBHIDMB_03979	8.7e-198	yhaX	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HFBHIDMB_03980	1.29e-261	yhaZ	-	-	L	-	-	-	DNA alkylation repair enzyme
HFBHIDMB_03981	7.46e-72	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HFBHIDMB_03982	7.19e-260	yheB	-	-	S	-	-	-	Belongs to the UPF0754 family
HFBHIDMB_03983	1.32e-273	yheC	-	-	HJ	-	-	-	YheC/D like ATP-grasp
HFBHIDMB_03984	0.0	yheD	-	-	HJ	-	-	-	YheC/D like ATP-grasp
HFBHIDMB_03985	2.27e-49	yheE	-	-	S	-	-	-	Family of unknown function (DUF5342)
HFBHIDMB_03986	1.25e-38	sspB	-	-	S	ko:K06418,ko:K06419,ko:K06420	-	ko00000	spore protein
HFBHIDMB_03987	1.29e-140	yheG	-	-	GM	-	-	-	NAD(P)H-binding
HFBHIDMB_03988	0.0	yheH	-	-	V	ko:K06147,ko:K18217,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HFBHIDMB_03989	0.0	yheI	-	-	V	ko:K18216,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HFBHIDMB_03990	3.6e-107	nhaX	-	-	T	-	-	-	Belongs to the universal stress protein A family
HFBHIDMB_03991	3.45e-301	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
HFBHIDMB_03992	9.07e-197	dat	2.6.1.21	-	E	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HFBHIDMB_03993	1.18e-192	nodB1	-	-	G	-	-	-	deacetylase
HFBHIDMB_03994	2.7e-176	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HFBHIDMB_03995	1.06e-258	yhdY	-	-	M	ko:K16052	-	ko00000,ko02000	Mechanosensitive ion channel
HFBHIDMB_03996	3.7e-09	yhdX	-	-	S	-	-	-	Uncharacterized protein YhdX
HFBHIDMB_03997	1.05e-171	yhdW	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HFBHIDMB_03998	1.38e-85	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HFBHIDMB_03999	2.48e-66	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HFBHIDMB_04000	0.0	yhdT	-	-	P	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HFBHIDMB_04001	5.1e-284	yhdR	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HFBHIDMB_04002	3.44e-97	cueR	-	-	K	ko:K11923	-	ko00000,ko03000	transcriptional
HFBHIDMB_04003	2.18e-304	yhdP	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HFBHIDMB_04004	3.9e-143	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HFBHIDMB_04005	2.74e-243	yhdN	-	-	C	-	-	-	Aldo keto reductase
HFBHIDMB_04006	3.24e-113	sigM	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HFBHIDMB_04007	6.13e-258	yhdL	-	-	S	-	-	-	Sigma factor regulator N-terminal
HFBHIDMB_04008	4.27e-59	yhdK	-	-	S	-	-	-	Sigma-M inhibitor protein
HFBHIDMB_04009	1.75e-100	-	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HFBHIDMB_04010	0.0	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HFBHIDMB_04011	5e-309	yhdH	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HFBHIDMB_04012	1.8e-291	yhdG	-	-	E	ko:K03294	-	ko00000	amino acid
HFBHIDMB_04013	1.84e-204	yhdF	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HFBHIDMB_04014	1.19e-257	citA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
HFBHIDMB_04015	2.01e-209	citR	-	-	K	ko:K19242	-	ko00000,ko03000	Transcriptional regulator
HFBHIDMB_04016	1.45e-203	lytE	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
HFBHIDMB_04017	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
HFBHIDMB_04018	0.0	spoVR	-	-	S	ko:K06415	-	ko00000	Stage V sporulation protein R
HFBHIDMB_04019	5.29e-307	ygxB	-	-	M	-	-	-	Conserved TM helix
HFBHIDMB_04020	1.37e-99	nsrR	-	-	K	ko:K13771	ko05132,map05132	ko00000,ko00001,ko03000	Transcriptional regulator
HFBHIDMB_04021	4.84e-275	lytF	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
HFBHIDMB_04022	1.02e-71	yhdC	-	-	S	-	-	-	Protein of unknown function (DUF3889)
HFBHIDMB_04023	1.65e-51	yhdB	-	-	S	-	-	-	YhdB-like protein
HFBHIDMB_04024	1.1e-114	yhdA	1.7.1.6	-	S	ko:K03206	-	ko00000,ko01000	NADPH-dependent FMN reductase
HFBHIDMB_04025	5.44e-144	yhcZ	-	-	K	ko:K02479	-	ko00000,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HFBHIDMB_04026	8.92e-271	yhcY	2.7.13.3	-	T	ko:K02480	-	ko00000,ko01000,ko01001,ko02022	Histidine kinase
HFBHIDMB_04027	0.0	pgcA	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase
HFBHIDMB_04028	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HFBHIDMB_04029	0.0	glpK	2.7.1.30	-	C	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HFBHIDMB_04030	5.7e-196	glpF	-	-	G	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HFBHIDMB_04031	5.35e-135	glpP	-	-	K	ko:K02443	-	ko00000,ko03000	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HFBHIDMB_04032	0.0	yhxA	-	-	E	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HFBHIDMB_04033	0.0	yhcX	-	-	K	-	-	-	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HFBHIDMB_04034	2.5e-154	yhcW	-	-	S	ko:K07025	-	ko00000	hydrolase
HFBHIDMB_04035	1.76e-90	yhcV	-	-	S	-	-	-	COG0517 FOG CBS domain
HFBHIDMB_04036	4.27e-89	yhcU	-	-	S	-	-	-	Family of unknown function (DUF5365)
HFBHIDMB_04037	4.78e-218	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HFBHIDMB_04038	5.1e-134	yhcS	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
HFBHIDMB_04039	0.0	yhcR	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01081,ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HFBHIDMB_04040	1.68e-146	yhcQ	-	-	M	-	-	-	Spore coat protein
HFBHIDMB_04041	1.09e-224	yhcP	-	-	-	-	-	-	-
HFBHIDMB_04042	3.47e-103	yhcN	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HFBHIDMB_04043	3.63e-60	yhcM	-	-	-	-	-	-	-
HFBHIDMB_04044	3.22e-65	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HFBHIDMB_04045	1.69e-114	-	-	-	S	-	-	-	Protein of unknown function (DUF2812)
HFBHIDMB_04046	2.62e-301	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HFBHIDMB_04047	3.36e-249	yhcK	2.7.7.65	-	T	ko:K18967	-	ko00000,ko01000,ko02000	COG2199 FOG GGDEF domain
HFBHIDMB_04048	9.06e-194	metQ_3	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HFBHIDMB_04049	1.91e-42	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
HFBHIDMB_04050	1.99e-211	yhcI	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HFBHIDMB_04051	3.59e-210	yhcH	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFBHIDMB_04052	3.24e-156	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFBHIDMB_04053	1.67e-79	yhcF	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator
HFBHIDMB_04054	4.14e-69	-	-	-	-	-	-	-	-
HFBHIDMB_04055	3.95e-59	yhcC	-	-	-	-	-	-	-
HFBHIDMB_04056	4.87e-128	yhcB	1.6.5.2	-	S	ko:K03809	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	Belongs to the WrbA family
HFBHIDMB_04057	0.0	yhcA	-	-	EGP	ko:K03446	-	ko00000,ko00002,ko02000	the major facilitator superfamily
HFBHIDMB_04058	2.67e-133	yhbJ	-	-	V	-	-	-	COG1566 Multidrug resistance efflux pump
HFBHIDMB_04059	1.29e-101	yhbI	-	-	K	ko:K15973	-	ko00000,ko03000	DNA-binding transcription factor activity
HFBHIDMB_04060	1.21e-286	yhbH	-	-	S	ko:K09786	-	ko00000	Belongs to the UPF0229 family
HFBHIDMB_04061	0.0	prkA	-	-	T	ko:K07180	-	ko00000	Ser protein kinase
HFBHIDMB_04062	4.28e-105	yhbF	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
HFBHIDMB_04063	2.66e-95	yhbE	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
HFBHIDMB_04064	3.4e-143	yhbD	-	-	K	-	-	-	Protein of unknown function (DUF4004)
HFBHIDMB_04065	6.53e-113	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HFBHIDMB_04066	2.77e-225	yhbB	-	-	S	-	-	-	Putative amidase domain
HFBHIDMB_04067	1.2e-283	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HFBHIDMB_04068	6.43e-146	yhzB	-	-	S	-	-	-	B3/4 domain
HFBHIDMB_04070	1.48e-39	-	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional regulator
HFBHIDMB_04071	5.19e-98	ygaO	-	-	-	-	-	-	-
HFBHIDMB_04072	4.82e-55	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HFBHIDMB_04074	9.35e-276	ssuD	1.14.14.28, 1.14.14.5	-	C	ko:K04091,ko:K20938	ko00920,map00920	ko00000,ko00001,ko01000	Catalyzes the desulfonation of aliphatic sulfonates
HFBHIDMB_04075	8.33e-190	ssuC	-	-	P	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HFBHIDMB_04076	8.45e-218	ssuA	-	-	M	ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Sulfonate ABC transporter
HFBHIDMB_04077	9.01e-179	ssuB	-	-	P	ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HFBHIDMB_04078	0.0	katA	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
HFBHIDMB_04080	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HFBHIDMB_04081	3.56e-166	ygaJ	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
HFBHIDMB_04082	1.58e-36	-	-	-	-	-	-	-	-
HFBHIDMB_04083	6.37e-185	spo0M	-	-	S	ko:K06377	-	ko00000	COG4326 Sporulation control protein
HFBHIDMB_04100	0.0	ybaR	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
HFBHIDMB_04102	4.71e-203	ybaS	-	-	S	-	-	-	Na -dependent transporter
HFBHIDMB_04103	1.89e-173	ybbA	-	-	S	ko:K07017	-	ko00000	Putative esterase
HFBHIDMB_04104	8.27e-227	feuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HFBHIDMB_04105	4.09e-226	feuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HFBHIDMB_04106	1.26e-216	feuA	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Iron-uptake system-binding protein
HFBHIDMB_04107	0.0	ybbB	-	-	K	ko:K21701	-	ko00000,ko03000	COG2207 AraC-type DNA-binding domain-containing proteins
HFBHIDMB_04108	6.68e-302	ybbC	-	-	S	-	-	-	protein conserved in bacteria
HFBHIDMB_04109	0.0	ybbD	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 3 family
HFBHIDMB_04110	0.0	ybbE	3.4.16.4	-	V	ko:K21469	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the UPF0214 family
HFBHIDMB_04111	8.5e-303	ybbF	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HFBHIDMB_04112	5.43e-194	ybbH	-	-	K	-	-	-	transcriptional
HFBHIDMB_04113	1.35e-209	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HFBHIDMB_04114	8.99e-114	ybbJ	-	-	J	-	-	-	acetyltransferase
HFBHIDMB_04115	2.43e-100	ybbK	-	-	S	-	-	-	Protein of unknown function (DUF523)
HFBHIDMB_04121	4.59e-127	sigW	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HFBHIDMB_04122	6.45e-151	rsiW	-	-	K	-	-	-	Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HFBHIDMB_04123	5.43e-189	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HFBHIDMB_04124	3.55e-291	ybbR	-	-	S	-	-	-	protein conserved in bacteria
HFBHIDMB_04125	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HFBHIDMB_04126	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HFBHIDMB_04127	2.87e-70	alkA	3.2.2.21	-	L	ko:K01247,ko:K13529	ko03410,map03410	ko00000,ko00001,ko01000,ko03000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HFBHIDMB_04128	1.27e-138	alkA	3.2.2.21	-	L	ko:K01247,ko:K13529	ko03410,map03410	ko00000,ko00001,ko01000,ko03000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HFBHIDMB_04129	3.98e-76	adaA	-	-	K	ko:K13530	-	ko00000,ko01000,ko03000,ko03400	Transcriptional regulator
HFBHIDMB_04130	4.32e-126	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HFBHIDMB_04131	0.0	ndhF	1.6.5.3	-	CP	ko:K05577	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HFBHIDMB_04132	0.0	ybcC	-	-	S	ko:K09822	-	ko00000	Belongs to the UPF0753 family
HFBHIDMB_04133	2.32e-119	ybcF	-	-	P	-	-	-	carbonic anhydrase
HFBHIDMB_04135	1.6e-63	-	-	-	-	-	-	-	-
HFBHIDMB_04136	7.26e-80	ybcI	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
HFBHIDMB_04137	3.85e-66	-	-	-	K	-	-	-	Helix-turn-helix domain
HFBHIDMB_04138	6.59e-258	ybcL	-	-	EGP	ko:K08164	-	ko00000,ko02000	COG2814 Arabinose efflux permease
HFBHIDMB_04139	9.98e-75	-	-	-	-	-	-	-	-
HFBHIDMB_04141	3.4e-179	ybdM	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
HFBHIDMB_04142	3.67e-193	ybdN	-	-	-	-	-	-	-
HFBHIDMB_04143	3.27e-276	ybdO	-	-	S	-	-	-	Domain of unknown function (DUF4885)
HFBHIDMB_04144	0.0	ybxG	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
HFBHIDMB_04145	5.46e-51	csgA	-	-	S	-	-	-	Sigma-G-dependent sporulation-specific SASP protein
HFBHIDMB_04146	6.92e-41	ybxH	-	-	S	-	-	-	Family of unknown function (DUF5370)
HFBHIDMB_04147	3.86e-195	ybxI	3.5.2.6	-	V	ko:K17838	ko01501,map01501	ko00000,ko00001,ko01000	beta-lactamase
HFBHIDMB_04148	7.67e-314	cypC	1.11.2.4	-	Q	ko:K15629	-	ko00000,ko00199,ko01000	Cytochrome P450
HFBHIDMB_04149	1.11e-54	ybyB	-	-	-	-	-	-	-
HFBHIDMB_04150	0.0	ybeC	-	-	E	-	-	-	amino acid
HFBHIDMB_04151	1.72e-211	glpQ	3.1.3.1, 3.1.4.46	-	C	ko:K01113,ko:K01126	ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	glycerophosphoryl diester phosphodiesterase
HFBHIDMB_04152	0.0	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	-transporter
HFBHIDMB_04153	1.02e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2651)
HFBHIDMB_04154	7.04e-217	ybfA	-	-	K	-	-	-	FR47-like protein
HFBHIDMB_04155	2.63e-284	ybfB	-	-	G	-	-	-	COG0477 Permeases of the major facilitator superfamily
HFBHIDMB_04158	0.0	ybfG	-	-	M	-	-	-	Domain of unknown function (DUF1906)
HFBHIDMB_04159	3.56e-206	ybfH	-	-	EG	-	-	-	EamA-like transporter family
HFBHIDMB_04160	7.39e-188	ybfI	-	-	K	-	-	-	AraC-like ligand binding domain
HFBHIDMB_04161	1.27e-43	-	-	-	K	-	-	-	sigma factor activity
HFBHIDMB_04162	2.73e-28	xhlB	-	-	S	-	-	-	SPP1 phage holin
HFBHIDMB_04163	2.12e-86	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HFBHIDMB_04164	8.93e-192	ypuA	-	-	S	-	-	-	Secreted protein
HFBHIDMB_04165	4.66e-41	ppiB	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HFBHIDMB_04166	8.64e-97	ppiB	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HFBHIDMB_04171	7.27e-26	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HFBHIDMB_04173	7.72e-57	-	-	-	-	-	-	-	-
HFBHIDMB_04174	1.63e-302	-	-	-	I	-	-	-	Pfam Lipase (class 3)
HFBHIDMB_04175	1.62e-37	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
HFBHIDMB_04177	3.29e-104	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
HFBHIDMB_04178	2.23e-136	rapK	-	-	S	ko:K06369	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
HFBHIDMB_04182	1.87e-107	-	-	-	S	-	-	-	Protein of unknown function (DUF3800)
HFBHIDMB_04183	1.73e-13	-	-	-	-	-	-	-	-
HFBHIDMB_04184	3.96e-84	-	-	-	O	-	-	-	Papain family cysteine protease
HFBHIDMB_04186	1.22e-29	-	-	-	L	ko:K01173	ko04210,map04210	ko00000,ko00001,ko03029	DNA/RNA non-specific endonuclease
HFBHIDMB_04187	3.82e-37	-	-	-	-	-	-	-	-
HFBHIDMB_04189	8.28e-56	ppiB	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HFBHIDMB_04191	6.74e-30	ypzJ	-	-	S	ko:K07069	-	ko00000	nucleic-acid-binding protein containing a Zn-ribbon domain
HFBHIDMB_04193	2.66e-122	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HFBHIDMB_04194	5.98e-72	ypuD	-	-	-	-	-	-	-
HFBHIDMB_04195	1.39e-258	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HFBHIDMB_04196	2.5e-147	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
HFBHIDMB_04197	2.1e-290	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HFBHIDMB_04198	3.43e-106	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HFBHIDMB_04199	1.12e-83	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HFBHIDMB_04200	1.19e-118	ypuF	-	-	S	ko:K09763	-	ko00000	Domain of unknown function (DUF309)
HFBHIDMB_04201	3.82e-167	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HFBHIDMB_04202	2e-135	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HFBHIDMB_04203	2.92e-126	ypuI	-	-	S	-	-	-	Protein of unknown function (DUF3907)
HFBHIDMB_04204	9.67e-272	dacB	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HFBHIDMB_04205	7.57e-135	spmA	-	-	S	ko:K06373	-	ko00000	Spore maturation protein
HFBHIDMB_04206	3.51e-113	spmB	-	-	S	ko:K06374	-	ko00000	Spore maturation protein
HFBHIDMB_04207	4.45e-169	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HFBHIDMB_04208	8.71e-128	resA	-	-	CO	-	-	-	Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HFBHIDMB_04209	0.0	resB	-	-	O	ko:K07399	-	ko00000	COG1333 ResB protein required for cytochrome c biosynthesis
HFBHIDMB_04210	4.67e-279	resC	-	-	O	-	-	-	'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HFBHIDMB_04211	1.69e-171	resD	-	-	T	ko:K07775	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HFBHIDMB_04212	0.0	resE	2.7.13.3	-	T	ko:K07651	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HFBHIDMB_04213	1.08e-133	sigX	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HFBHIDMB_04214	1.95e-236	rsiX	-	-	-	-	-	-	-
HFBHIDMB_04215	4.79e-174	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HFBHIDMB_04216	0.0	serA	1.1.1.399, 1.1.1.95	-	E	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFBHIDMB_04217	3.07e-122	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HFBHIDMB_04218	8.35e-55	fer	-	-	C	ko:K05337	-	ko00000	Ferredoxin
HFBHIDMB_04219	4.47e-255	ypbB	5.1.3.1	-	S	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	protein conserved in bacteria
HFBHIDMB_04220	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
HFBHIDMB_04221	3.55e-128	ypbD	-	-	S	ko:K07052	-	ko00000	metal-dependent membrane protease
HFBHIDMB_04222	8.27e-143	ypbE	-	-	M	-	-	-	Lysin motif
HFBHIDMB_04223	4.08e-106	ypbF	-	-	S	-	-	-	Protein of unknown function (DUF2663)
HFBHIDMB_04224	6.15e-188	ypbG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
HFBHIDMB_04225	5.56e-136	mecB	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HFBHIDMB_04226	4.08e-308	gudB	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HFBHIDMB_04227	6.04e-223	ypdA	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	COG0492 Thioredoxin reductase
HFBHIDMB_04228	1.76e-153	prsW	-	-	S	-	-	-	Involved in the degradation of specific anti-sigma factors
HFBHIDMB_04229	1.1e-204	sleB	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Spore cortex-lytic enzyme
HFBHIDMB_04230	0.0	ypeB	-	-	H	ko:K06313	-	ko00000	sporulation protein
HFBHIDMB_04231	8.95e-142	ypfA	-	-	M	-	-	-	Flagellar protein YcgR
HFBHIDMB_04232	2.48e-32	-	-	-	S	-	-	-	Family of unknown function (DUF5359)
HFBHIDMB_04233	3.91e-144	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HFBHIDMB_04234	7.8e-262	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HFBHIDMB_04235	5.43e-234	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HFBHIDMB_04236	1.13e-11	-	-	-	S	-	-	-	YpzI-like protein
HFBHIDMB_04237	3.87e-134	yphA	-	-	-	-	-	-	-
HFBHIDMB_04238	4.35e-207	yphB	-	-	S	ko:K05739	-	ko00000	YIEGIA protein
HFBHIDMB_04239	2.06e-38	ypzH	-	-	-	-	-	-	-
HFBHIDMB_04240	1.72e-315	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HFBHIDMB_04241	2.01e-243	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HFBHIDMB_04242	7.09e-27	yphE	-	-	S	-	-	-	Protein of unknown function (DUF2768)
HFBHIDMB_04243	4.31e-176	yphF	-	-	-	-	-	-	-
HFBHIDMB_04244	0.0	spoIVA	-	-	S	ko:K06398	-	ko00000	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HFBHIDMB_04245	1.07e-57	hbs	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HFBHIDMB_04246	2.55e-130	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
HFBHIDMB_04247	5.13e-46	mtrB	-	-	K	ko:K06285	-	ko00000,ko03000	Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
HFBHIDMB_04248	7.17e-177	hepS	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
HFBHIDMB_04249	1.34e-169	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HFBHIDMB_04250	4.09e-249	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HFBHIDMB_04251	2.17e-104	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HFBHIDMB_04252	2.13e-182	cheR	2.1.1.80	-	NT	ko:K00575	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko01000,ko02035	COG1352 Methylase of chemotaxis methyl-accepting proteins
HFBHIDMB_04253	5.88e-277	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HFBHIDMB_04254	5.72e-263	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HFBHIDMB_04255	9.82e-84	aroH	5.4.99.5	-	E	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
HFBHIDMB_04256	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HFBHIDMB_04257	8.47e-221	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HFBHIDMB_04258	4.18e-145	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
HFBHIDMB_04259	8.71e-148	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
HFBHIDMB_04260	1.81e-292	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HFBHIDMB_04261	3.82e-186	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HFBHIDMB_04262	3.7e-258	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HFBHIDMB_04263	1.21e-264	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
HFBHIDMB_04264	1.64e-300	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HFBHIDMB_04265	3.56e-297	ypiA	-	-	S	-	-	-	COG0457 FOG TPR repeat
HFBHIDMB_04266	1.83e-129	ypiB	-	-	S	-	-	-	Belongs to the UPF0302 family
HFBHIDMB_04267	5.55e-100	ypiF	-	-	S	-	-	-	Protein of unknown function (DUF2487)
HFBHIDMB_04268	3.35e-126	qcrA	-	-	C	ko:K03886	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Menaquinol-cytochrome c reductase
HFBHIDMB_04269	8.76e-166	qcrB	-	-	C	ko:K03887	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	COG1290 Cytochrome b subunit of the bc complex
HFBHIDMB_04270	5.71e-191	qcrC	-	-	C	ko:K03888	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Menaquinol-cytochrome c reductase cytochrome b c subunit
HFBHIDMB_04271	6.63e-125	ypjA	-	-	S	-	-	-	membrane
HFBHIDMB_04272	2.79e-182	ypjB	-	-	S	-	-	-	sporulation protein
HFBHIDMB_04273	3.7e-200	ypjC	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)